CN107753389A - A kind of recombined collagen foaming pectin facial mask and preparation method thereof - Google Patents

A kind of recombined collagen foaming pectin facial mask and preparation method thereof Download PDF

Info

Publication number
CN107753389A
CN107753389A CN201611076705.7A CN201611076705A CN107753389A CN 107753389 A CN107753389 A CN 107753389A CN 201611076705 A CN201611076705 A CN 201611076705A CN 107753389 A CN107753389 A CN 107753389A
Authority
CN
China
Prior art keywords
parts
facial mask
acid
collagen
pectin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201611076705.7A
Other languages
Chinese (zh)
Inventor
钱松
丁文贺
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jiangsu Chuang Ming Medical Instrument Co Ltd
Original Assignee
Jiangsu Chuang Ming Medical Instrument Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jiangsu Chuang Ming Medical Instrument Co Ltd filed Critical Jiangsu Chuang Ming Medical Instrument Co Ltd
Priority to CN201611076705.7A priority Critical patent/CN107753389A/en
Publication of CN107753389A publication Critical patent/CN107753389A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • A61K8/988Honey; Royal jelly, Propolis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Zoology (AREA)
  • Cosmetics (AREA)

Abstract

The invention belongs to cosmetic technical field, is related to a kind of recombined collagen foaming pectin facial mask.Recombined collagen foaming pectin facial mask of the present invention is by humanization genetic recombination collagen, deionized water, glycerine, citric acid, xanthans, sodium citrate, 1,2 pentanediol, the laurate of polyglycereol 10,1,3 propane diols, tamarind seed glue, sodium acid carbonate, ferment honey, micromolecule hyaluronic acid, plant extract solution and hydrolysis royal jelly albumen composition;The plant extract solution includes radix cynanchi atrati flower extract, honeysuckle leaf extract, shamrock extract.Recombined collagen foaming pectin facial mask of the present invention uses two seed pod gelatinised matrix, organic acid is substantially dissolved in matrix and then is fully reacted, colloid acid-base value is reached consistent, solve the problems, such as the inconsistent skin brought of carbonic acid facial mask acid-base value.

Description

A kind of recombined collagen foaming pectin facial mask and preparation method thereof
Technical field
The invention belongs to cosmetic technical field, and in particular to a kind of recombined collagen foaming pectin facial mask and its preparation Method.
Background technology
With the development of science and technology with the continuous improvement of living standards of the people, cosmetics are in people live in occupation of more Carry out more consequence, this has also driven the continuous development of cosmetic chemistry.In recent years, the kind of cosmetics is on the increase, its Feature is also more and more stronger.One of the mainstream product of facial mask as cosmetics, has also obtained significant progress.
Carbonic acid facial mask is to mix gel and powder, and so as to which caused carbon dioxide is deep into skin, it is dense to improve blood Degree, inject oxygen to skin.Promote skin blood circulation and skin cell metabolism, waste is effectively excluded, so as to obtain Smooth fine and smooth skin as baby.Existing market carbonic acid facial mask is in stirring at normal temperature by No.1 powdered substrate and No. two gel-type vehicles Lower hybrid reaction and obtain.No.1 powdered substrate is slant acidity matrix, and powder reacts generation carbon dioxide under agitation with gel, and Powder is not easy quickly to dissolve at normal temperatures, No.1 matrix and No. two matrix is occurred the local acid of colloid after reaction during the course of the reaction Basicity is inconsistent and destroys skin protective barrier, and moisturizing water lock ability reduces, intensely dark pool, the skin problem such as easy sensitivity.
So develop a kind of carbonic acid facial mask substitute, there is provided a kind of consistent facial mask of colloid acid-base value has important meaning Justice.
The content of the invention
The purpose of the present invention is to overcome existing carbonic acid facial mask mesostroma colloid part acid-base value is inconsistent during the course of the reaction And skin protective barrier is destroyed, moisturizing water lock ability reduces, the intensely dark pool of skin, the skin problem such as easy sensitivity, there is provided a kind of Humanization genetic recombination collagen foaming pectin facial mask.Humanization genetic recombination collagen foaming pectin facial mask of the present invention is adopted With two seed pod gelatinised matrix, organic acid is substantially dissolved in matrix and then is fully reacted, colloid acid-base value is reached consistent, solve The inconsistent skin problem brought of carbonic acid facial mask acid-base value of having determined.
According to the first aspect of the invention, the invention provides a kind of humanization genetic recombination collagen foaming pectin Facial mask, the humanization genetic recombination collagen foaming pectin facial mask is by humanization genetic recombination collagen, deionization Water, glycerine, citric acid, xanthans, sodium citrate, 1,2- pentanediol, Natrulon H-10 laurate, 1,3-PD, tamarind seed Glue, sodium acid carbonate, ferment honey, micromolecule hyaluronic acid, plant extract solution and hydrolysis royal jelly albumen composition, the plant Thing extract solution includes radix cynanchi atrati flower extract, honeysuckle leaf extract, shamrock extract.
The humanization genetic recombination collagen is the humanization obtained according to the teaching in ZL201310033299.6 Genetic recombination collagen, it is made up of water-soluble glue former peptide, the characteristic structural with collagen:G-X-Y repetitive structures, G represents glycine (Glycine), and Y is based on proline (Proline).Recombinant collagen forms a thin layer collagen in skin surface Protein film mechanism is covered in outside skin cuticula absorbs moisture from air, prevents in cuticula that moisture outwardly evaporates and plays Moisturizing water lock, improve horn cell water content.With the extension of residence time, outside environmental elements (ultraviolet, heat radiation, Oxidative environment dusty gas etc.) and various interior environmental factors (free radical, enzyme, mechanical force, microorganism etc.) collective effect Under, macromolecular collagen peptide starts to be disintegrated, and along corneocyte gap, sweat gland, hair follicle, sebaceous glands hole to skin deep layer Gradually permeate, the molecular weight of humanization genetic recombination collagen albumen, which reduces, in process of osmosis turns into small molecule active collagen Peptide, reach skin corium space between cells and fill damaged part together with cell secretion self collagen, these small molecule collagen peptides play Its biological activity, promote the raising of skin corium fibroblast quantity and vigor, synthesize more self collagens to reach Skin barrier is repaired, bright color, anti-wrinkle of compacting, moisturizing and nourishing, whitening spot-removing is sun-proof, antiallergic and other effects.
Described fermentation honey pH value is 3.0, is made by peach blossom ferment spontaneous fermentation honey, the glucose containing high concentration Acid, the activity changed with water concentration of skin tissue's protease can be improved, accelerating cuticula metabolism makes skin calmness pigment And dyeing disappears and improves skin brightness and reach and highlight shining skin effect.
The hydrolysis royal jelly albumen by weight percentage, is made up of following components:Isoleucine 5.16%, valine 6.13%, leucine 5.81%, histidine 5.16%, lysine 8.71%, arginine 5.15%, methionine 0.81%, the third ammonia Acid 3.55%, cystine 1.77%, aspartic acid 20.65%, phenylalanine 4.19%, glutamic acid 9.68%, tyrosine 5.16%, glycine 2.42%, threonine 3.87%, proline-4 .84%, tryptophan 1.13%, serine 5.81%.This hair Bright hydrolysis royal jelly albumen can increase skin collagen caused by skin collagen content containment UV ray or other external causes The quantitative change or qualitative change of albumen, prevent cutis laxa from keeping skin health, not by outside stimulus, bring silk to slide tender sense to skin.
The aqueous solution of the micromolecule hyaluronic acid 0.5%wt, pH=5.0~8.5 is measured at 25 DEG C, measured under 280nm Light transmittance >=99.0% is measured under absorbance≤0.25,550nm;It is transparent by weight percentage in the micromolecule hyaluronic acid Matter acid sodium >=92.0%, protein≤0.1%;Glucuronic acid percentage by weight >=44.5% in the Sodium Hyaluronate;This Invention small molecular hyaluronic acid can enter hypodermis with rapid osmotic, quickly establish the water profit of epidermis, corium, hypodermis Environment, " subcutaneous reservoir " and epidermis " water storage ", UNICOM's mechanism of " water delivery " are established, Skin Cell is become water profit, it is shown that Strong deep water supplement effect;Take the molecular weight hyaluronic acid of quality in the present invention can be with humanization genetic recombination collagen egg White cooperation uses in cosmetics, can accelerate building for " subcutaneous reservoir " (the water storage network that collagen is woven into sodium hyaluronate) It is vertical, it is suppressed that free radical triggers the occurrence probability of melanin, desalinates pigment, makes the increase of cell transparency, forms significant whitening Effect and light spot effect;Can stimulating endothelial cell identification injury, so as to carry out initial protection to injury and repair It is multiple, promote wound healing effect, capillary can be effectively facilitated and formed, improve skin colour jaundice, for eliminating red blood silk, resist Wrinkle, anti-ageing positive effect.
The plant extract solution includes radix cynanchi atrati flower extract, honeysuckle leaf extract, shamrock extract;Specific institute Plant extract solution is stated by weight percentage by 50% butanediol, and 48.5% water, 0.5% radix cynanchi atrati flower extract, 0.5% bears Winter leaf extract, the mixed liquor of 0.5% shamrock extract composition;The plant extracts outward appearance is faint yellow, nonirritant gas Taste, pH value 4.0-6.5, proportion 0.980-1.100, mercury≤1ppm, lead≤40ppm, arsenic≤10ppm;Plant extract in the present invention Thing mixing liquid energy inhibits inflammatory factor prostaglandin E2, tumor necrosis factor-alpha, nitric oxide, the generation of interleukin-11, regulation The key factor of damaged tissues, it helps to recover impaired skin and alleviates skin irritatin caused by chemical composition in cosmetics And the problems such as aging.
According to another aspect of the present invention, present invention also offers a kind of system of recombined collagen foaming pectin facial mask Preparation Method, the humanization genetic recombination collagen foaming pectin facial mask hydrolyze honeybee by humanization genetic recombination collagen Royal jelly protein, ferment honey, and micromolecule hyaluronic acid, radix cynanchi atrati flower extract, honeysuckle leaf extract and shamrock extract are to carbon Sour foam mask is modified gained, comprises the following steps:
(1) No.1 pectic matrix is made
In terms of parts by weight, by the deionized water of 10-30 parts, the glycerine of 30-70 parts, the citric acid of 1-5 parts, 0.5-2 parts Sodium citrate, 1, the 2- pentanediols of 1-5 parts, the Natrulon H-10 laurate of 0.5-2 parts, the xanthans of 0.3-2 parts adds successively Enter, be heated to 85 DEG C of stirring and dissolvings and be incubated 30 minutes, be cooled to 45 DEG C;
(2) No. two pectic matrix are made
In terms of weight fraction, by the deionized water of 50-80 parts, the 1,3-PD of 3-5 parts, the tamarind seed glue of 1-5 parts, 2- 4 parts of sodium acid carbonate, 1, the 2- pentanediols of 1-3 parts, the micromolecule hyaluronic acid of 0.1-1 parts sequentially add, be heated to 85 DEG C it is molten Solution insulation 30 minutes, is cooled to the mixed liquor that 1-5 parts are sequentially added after 45 DEG C, the humanization genetic recombination collagen egg of 1-10 parts In vain, the hydrolysis royal jelly albumen of 3-5 parts, the fermentation honey dissolving of 1-5 parts;
(3) it is 1 by weight by No.1 pectic matrix and No. two pectic matrix:1 ratio is added in container and quickly stirred Obtain humanization genetic recombination collagen foaming pectin facial mask.
According to a further aspect of the invention, the invention provides a kind of humanization genetic recombination collagen foaming pectin The application method of facial mask:It is first that skin or facial cleansing is clean before face mask film;By No.1 matrix and No. two matrix by weight Than for 1:1 ratio is added in container and was stirred with scraper plate within 1 minute, two kinds of matrix is fully reacted;Facial mask is coagulated Glue is applied to skin or face (avoiding eyes) about 1-2mm is thick, is peeled off slowly with slow with one's hands after keeping 15 minutes freezing films, Use is later without cleaning face.
The present invention uses two seed pod gelatinised matrix in the synthesis of matrix, organic acid is substantially dissolved in matrix and then fills Divide reaction, colloid acid-base value is reached consistent.Add humanization genetic recombination collagen albumen and fermentation honey maintenance skin Barrier, shine skin bright color;Adding micromolecule hyaluronic acid being capable of hypersynchronous moisturizing water lock;Shamrock extract is added, in vain Common vetch flower extract, honeysuckle leaf extract help skin to resist outside stimulus, recover damaged skin and suppress inflammatory factor generation;Addition Hydrolysis royal jelly albumen can highly resist skin external irritant and promote collagen generation.
Compared with prior art, the invention has the advantages that:
The present invention solves the skin sensitivity that two kinds of substrate reactions are not exclusively brought in prior art carbonic acid facial mask, moisture stream Lose, dark yellow matt problem;The present invention uses recombined collagen respectively, hydrolyzes royal jelly albumen, and ferment honey, and small molecule is transparent Matter acid, radix cynanchi atrati flower extract, honeysuckle leaf extract, shamrock extract are modified carbonic acid facial mask, humanization base by certain proportioning Because of recombined collagen first extracellular small-molecular peptides and amino acid resolved into, enter back into blood circulation through collagen enzyme effects, It is then that the tropocollagen molecule first effect through enzyme is broken into the fragment of appropriate molecular size range and is phagocytized by cells in the cell, in cell Micromolecule polypeptide and amino acid are inside further broken down into so as to nutrition needed for skin supplement;Secondly collagen with small point Increase collagen content and the metabolism of hypodermis under the interaction of sub- hyaluronic acid, reach deep layer cleaning, moisturizing water lock Effect;Improve the skin problem that the reaction of carbonic acid facial mask is not exclusively brought.
Embodiment
To make the object, technical solutions and advantages of the present invention of greater clarity, with reference to embodiment, to this Invention is further described.It should be understood that these descriptions are merely illustrative, and it is not intended to limit the scope of the present invention.
Raw materials used middle humanization genetic recombination collagen purchase is limited from the Xi'an glad biotechnology of benefit power in the present invention Company, remaining is commercially available conventional cosmetic rank raw material.
Embodiment
Recombined collagen foaming pectin making face mask method
(1) No.1 pectic matrix is made
In terms of parts by weight, by the deionized water of 10-30 parts, the glycerine of 30-70 parts, the citric acid of 1-5 parts, 0.5-2 parts Sodium citrate, 1, the 2- pentanediols of 1-5 parts, the Natrulon H-10 laurate of 0.5-2 parts, the xanthans of 0.3-2 parts adds successively Enter, be heated to 85 DEG C of stirring and dissolvings and be incubated 30 minutes, be cooled to 45 DEG C;
(2) No. two pectic matrix are made
In terms of weight fraction, by the deionized water of 50-80 parts, the 1,3-PD of 3-5 parts, the tamarind seed glue of 1-5 parts, 2- 4 parts of sodium acid carbonate, 1, the 2- pentanediols of 1-3 parts, the micromolecule hyaluronic acid of 0.1-1 parts sequentially add, be heated to 85 DEG C it is molten Solution insulation 30 minutes, is cooled to the mixed liquor that 1-5 parts are sequentially added after 45 DEG C, the humanization genetic recombination collagen egg of 1-10 parts In vain, the hydrolysis royal jelly albumen of 3-5 parts, the fermentation honey dissolving of 1-5 parts;
(3) it is 1 by weight by No.1 pectic matrix and No. two pectic matrix:1 ratio is added in container and quickly stirred Obtain recombined collagen foaming pectin facial mask.
It is first that skin or facial cleansing is clean before face mask film;It is 1 by weight by No.1 matrix and No. two matrix:1 Ratio add container in be stirred with scraper plate within 1 minute, two kinds of matrix is fully reacted;Facial mask gel is applied to Skin or face (avoiding eyes) about 1-2mm are thick, are peeled off slowly with slow with one's hands after keeping 15 minutes freezing films, after use Without cleaning face.
Described fermentation honey pH value is 3.0, is made by peach blossom ferment spontaneous fermentation honey.
The hydrolysis royal jelly albumen by weight percentage, is made up of following components:Isoleucine 5.16%, valine 6.13%, leucine 5.81%, histidine 5.16%, lysine 8.71%, arginine 5.15%, methionine 0.81%, the third ammonia Acid 3.55%, cystine 1.77%, aspartic acid 20.65%, phenylalanine 4.19%, glutamic acid 9.68%, tyrosine 5.16%, glycine 2.42%, threonine 3.87%, proline-4 .84%, tryptophan 1.13%, serine 5.81%.
The aqueous solution of the micromolecule hyaluronic acid 0.5%wt, pH=5.0~8.5 is measured at 25 DEG C, measured under 280nm Light transmittance >=99.0% is measured under absorbance≤0.25,550nm;It is transparent by weight percentage in the micromolecule hyaluronic acid Matter acid sodium >=92.0%, protein≤0.1%;Glucuronic acid percentage by weight >=44.5% in the Sodium Hyaluronate.
The plant extract solution includes radix cynanchi atrati flower extract, honeysuckle leaf extract, shamrock extract;Specific institute Plant extract solution is stated by weight percentage by 50% butanediol, and 48.5% water, 0.5% radix cynanchi atrati flower extract, 0.5% bears Winter leaf extract, the mixed liquor of 0.5% shamrock extract composition;The plant extracts outward appearance is faint yellow, nonirritant gas Taste, pH value 4.0-6.5, proportion 0.980-1.100, mercury≤1ppm, lead≤40ppm, arsenic≤10ppm.
The recombined collagen foaming pectin facial mask prepared to the embodiment of the present invention carries out clinical effectiveness test:
First, the experiment of cutin-softening layer is repaired to skin moisture-keeping
Patient:33 years old women, skin face is partially dry, difficult cleaning of skin after surfactant cleaning be present.Make Foregoing application method is pressed with recombined collagen foaming pectin facial mask, skin moisture-keeping after being used 7 days using one-time continuous daily The obvious increase of degree, the obvious frivolous ventilative of cuticula, makes skin plentiful flexible, solves skin cleaning problems from inside.Illustrate this Invention recombined collagen foaming pectin facial mask has the effect of repairing cutin and maintaining cutin complete.
2nd, skin collagen is lost in, the experiment of sluggish metabolism, allergic problem
48 years old women, skin senescence, wrinkle increase, sluggish metabolism, allergic skin be present.Use restructuring glue Former albumen foams pectin facial mask, daily using one-time continuous using adding skin collagen content after 10 days, hence it is evident that improve The wrinkle of skin more than 50% is reduced, solves the problems, such as skin hypersensitivity skin.Illustrate the present invention have promote keratinocyte differentiation and Worked in terms of skin renewal.
3rd, to facial whelk, the experiment of acne print
Small pox, acne print problem be present in 18 years old males, puberty face.According to making for recombined collagen foaming pectin facial mask With method, substantially mitigated using 1 day whelk, continuous use solves the problems, such as facial small pox in 2 days;It is obvious that 7 days acne prints are used continuously Shoal, continuous use easily solves the problems, such as facial acne print in 15 days.
4th, to eye livid ring around eye, the experiment of pouch
65 years old women, to eye livid ring around eye, pouch problem according to recombined collagen foam pectin facial mask application method, Livid ring around eye, pouch problem were obviously improved using 1 day, being used continuously 3 days easily improves 90% livid ring around eye problem, and 80% pouch is asked Topic.
Effect proves through clinical usage, recombined collagen foaming pectin facial mask prepared by the present invention have repair cutin and The effect of maintaining cutin complete, good moisturizing effect, it can promote to work in terms of keratinocyte differentiation and skin renewal, And play facilitation in terms of being able to maintain that skin normal function.
Although embodiments of the present invention are described in detail, it should be understood that, without departing from the present invention's In the case of spirit and scope, embodiments of the present invention can be made with various changes, replacement and change.

Claims (7)

  1. The pectin facial mask 1. a kind of recombined collagen foams, the recombined collagen foaming pectin facial mask is by humanization gene Recombined collagen, deionized water, glycerine, citric acid, xanthans, sodium citrate, 1,2- pentanediol, Natrulon H-10 laurate Ester, 1,3-PD, tamarind seed glue, sodium acid carbonate, ferment honey, micromolecule hyaluronic acid, plant extract solution and hydrolysis Royal jelly albumen forms;The plant extract solution includes radix cynanchi atrati flower extract, honeysuckle leaf extract, shamrock extract.
  2. The pectin facial mask 2. recombined collagen according to claim 1 foams, it is characterised in that:Described fermentation honey pH Be worth for 3.0, it is made by peach blossom ferment spontaneous fermentation honey.
  3. The pectin facial mask 3. recombined collagen according to claim 1 foams, it is characterised in that:The hydrolysis royal jelly egg In vain by weight percentage, it is made up of following components:Isoleucine 5.16%, valine 6.13%, leucine 5.81%, organize ammonia Acid 5.16%, lysine 8.71%, arginine 5.15%, methionine 0.81%, alanine 3.55%, cystine 1.77%, day Winter propylhomoserin 20.65%, phenylalanine 4.19%, glutamic acid 9.68%, tyrosinase 15 .16%, glycine 2.42%, threonine 3.87%, proline-4 .84%, tryptophan 1.13%, serine 5.81%.
  4. The pectin facial mask 4. recombined collagen according to claim 1 foams, it is characterised in that:The small molecule hyalomitome The sour 0.5%wt aqueous solution, pH=5.0~8.5 is measured at 25 DEG C, measure under 280nm and measured under absorbance≤0.25,550nm Light transmittance >=99.0%;Sodium Hyaluronate >=92.0% by weight percentage in the micromolecule hyaluronic acid, protein≤ 0.1%;Glucuronic acid percentage by weight >=44.5% in the Sodium Hyaluronate.
  5. The pectin facial mask 5. recombined collagen according to claim 1 foams, it is characterised in that:The plant extracts is molten Liquid is by weight percentage by 50% butanediol, 48.5% water, 0.5% radix cynanchi atrati flower extract, 0.5% honeysuckle leaf extract, The mixed liquor of 0.5% shamrock extract composition.
  6. The pectin facial mask 6. recombined collagen according to claim 1 foams, it is characterised in that:The plant extracts is molten Liquid outward appearance is faint yellow, has no irritating odor, pH value 4.0-6.5, proportion 0.980-1.100, and mercury in plant extract solution≤ 1ppm, lead≤40ppm, arsenic≤10ppm.
  7. 7. a kind of preparation method of the recombined collagen foaming pectin facial mask described in any one of claim 1-6, including it is following Step:
    (1) No.1 pectic matrix is made
    In terms of parts by weight, by the deionized water of 10-30 parts, the glycerine of 30-70 parts, the citric acid of 1-5 parts, the lemon of 0.5-2 parts Lemon acid sodium, 1, the 2- pentanediols of 1-5 parts, the Natrulon H-10 laurate of 0.5-2 parts, the xanthans of 0.3-2 parts sequentially add, It is heated to 85 DEG C of stirring and dissolvings and is incubated 30 minutes, is cooled to 45 DEG C;
    (2) No. two pectic matrix are made
    In terms of weight fraction, by the deionized water of 50-80 parts, the 1,3-PD of 3-5 parts, the tamarind seed glue of 1-5 parts, 2-4 parts Sodium acid carbonate, 1, the 2- pentanediols of 1-3 parts, the micromolecule hyaluronic acid of 0.1-1 parts sequentially adds, and is heated to 85 DEG C of dissolvings and protects Temperature 30 minutes, is cooled to the plant extract solution that 1-5 parts are sequentially added after 45 DEG C, the humanization genetic recombination collagen of 1-10 parts Albumen, the hydrolysis royal jelly albumen of 3-5 parts, the fermentation honey dissolving of 1-5 parts;
    (3) it is 1 by weight by No.1 pectic matrix and No. two pectic matrix:1 ratio adds quick stirring in container and obtained Recombined collagen foaming pectin facial mask.
CN201611076705.7A 2016-11-30 2016-11-30 A kind of recombined collagen foaming pectin facial mask and preparation method thereof Pending CN107753389A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201611076705.7A CN107753389A (en) 2016-11-30 2016-11-30 A kind of recombined collagen foaming pectin facial mask and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201611076705.7A CN107753389A (en) 2016-11-30 2016-11-30 A kind of recombined collagen foaming pectin facial mask and preparation method thereof

Publications (1)

Publication Number Publication Date
CN107753389A true CN107753389A (en) 2018-03-06

Family

ID=61263722

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201611076705.7A Pending CN107753389A (en) 2016-11-30 2016-11-30 A kind of recombined collagen foaming pectin facial mask and preparation method thereof

Country Status (1)

Country Link
CN (1) CN107753389A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109010083A (en) * 2018-09-07 2018-12-18 广州华玺生物科技有限公司 A kind of carbon dioxide composite facial mask composition of layered structure and preparation method thereof constituted with amphiphilic substance
CN113520899A (en) * 2021-03-25 2021-10-22 甘肃天际生物科技有限公司 Recombinant collagen product for skin photodamage repair
CN114796594A (en) * 2022-04-08 2022-07-29 湖南有美生物科技有限公司 Preparation method and application of yeast recombinant collagen liquid dressing
CN115998636A (en) * 2023-03-24 2023-04-25 江苏亨瑞生物医药科技有限公司 Gel mask containing recombinant humanized collagen and preparation method thereof

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101530456A (en) * 2009-03-04 2009-09-16 河北医科大学 Method for extracting antioxidant active substance in clover
CN102309437A (en) * 2010-06-29 2012-01-11 森图容有限公司 Carbon dioxide-containing viscous cosmetic composition
CN103102407A (en) * 2013-01-29 2013-05-15 西安益力欣生物科技有限公司 Genetic recombinant human-like collagen
CN103860388A (en) * 2014-03-25 2014-06-18 佛山圣婕妮生物科技有限公司 Effervescent facial mask powder, as well as preparation method and facial mask thereof
CN104490703A (en) * 2014-12-24 2015-04-08 广州丹奇日用化工厂有限公司 Moisture retention and skin whitening cosmetic composition and preparation method thereof
CN104721099A (en) * 2015-04-17 2015-06-24 广州市德蓓化妆品有限公司 Deep-purification black facial mask capable of generating bubbles and production method thereof
CN105769625A (en) * 2016-05-08 2016-07-20 杭州氧泡泡生物科技有限公司 Carbonic acid-oxygen bubble cleansing mask

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101530456A (en) * 2009-03-04 2009-09-16 河北医科大学 Method for extracting antioxidant active substance in clover
CN102309437A (en) * 2010-06-29 2012-01-11 森图容有限公司 Carbon dioxide-containing viscous cosmetic composition
CN103102407A (en) * 2013-01-29 2013-05-15 西安益力欣生物科技有限公司 Genetic recombinant human-like collagen
CN103860388A (en) * 2014-03-25 2014-06-18 佛山圣婕妮生物科技有限公司 Effervescent facial mask powder, as well as preparation method and facial mask thereof
CN104490703A (en) * 2014-12-24 2015-04-08 广州丹奇日用化工厂有限公司 Moisture retention and skin whitening cosmetic composition and preparation method thereof
CN104721099A (en) * 2015-04-17 2015-06-24 广州市德蓓化妆品有限公司 Deep-purification black facial mask capable of generating bubbles and production method thereof
CN105769625A (en) * 2016-05-08 2016-07-20 杭州氧泡泡生物科技有限公司 Carbonic acid-oxygen bubble cleansing mask

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
佚名: "Beauty bubble 碳酸泡泡面膜", 《COSDNA》 *
佚名: "Biotherm White D-Tox Cellular Cellular regenerating intensive moisture white mask深海源萃白清肌面膜", 《COSDNA》 *
佚名: "本原装进口iN-BE+V CARBO-GEL-PACK高浓度碳酸CO2面膜", 《COSDNA》 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109010083A (en) * 2018-09-07 2018-12-18 广州华玺生物科技有限公司 A kind of carbon dioxide composite facial mask composition of layered structure and preparation method thereof constituted with amphiphilic substance
CN109010083B (en) * 2018-09-07 2021-11-02 广州华玺生物科技有限公司 Carbon dioxide composite facial mask composition with layered structure composed of amphiphilic substances and preparation method thereof
CN113520899A (en) * 2021-03-25 2021-10-22 甘肃天际生物科技有限公司 Recombinant collagen product for skin photodamage repair
CN114796594A (en) * 2022-04-08 2022-07-29 湖南有美生物科技有限公司 Preparation method and application of yeast recombinant collagen liquid dressing
CN115998636A (en) * 2023-03-24 2023-04-25 江苏亨瑞生物医药科技有限公司 Gel mask containing recombinant humanized collagen and preparation method thereof

Similar Documents

Publication Publication Date Title
CN107753389A (en) A kind of recombined collagen foaming pectin facial mask and preparation method thereof
WO2020244167A1 (en) Cellular energy repair composition
CN102125512A (en) Composition with whitening and freckle-dispelling functions
CN111166690A (en) Skin anti-aging oligopeptide composition and preparation method thereof
CN112426401A (en) Essence capable of tightening, tendering and brightening eyes and preparation method thereof
CN103705428A (en) Non-ionic composition used for removing keratin and preparation method of non-ionic composition
CN109044946A (en) A kind of whitening and moisturizing facial mask liquid and its preparation process
CN109758402A (en) It is a kind of it is living can life stoste and preparation method thereof
CN111870540A (en) Medical repairing facial mask and preparation method thereof
CN111568797A (en) Composition for quickly removing fine lines and application thereof
CN114983856A (en) Blue copper peptide solution with permeation promoting system and preparation method and application thereof
CN107714631A (en) A kind of collagen peptide facial mask liquid and preparation method thereof
CN101130067A (en) Preparation for replenishing collagen and method of preparing the same
CN112120956A (en) Polypeptide composition for repairing damaged skin
CN111419785A (en) Production process of miracle water essence for skin care product
CN116509750A (en) Composite fish collagen mask liquid and preparation method thereof
CN110522694A (en) A kind of bright face frost of net skin and preparation method thereof
CN109481332A (en) A kind of polypeptide replenishing water and preserving moisture skin lightening facial mask and preparation method thereof
JP5985795B2 (en) Method for producing sericin peptide
CN108186438A (en) A kind of after-sun gel containing Porcine HGF and preparation method thereof
CN114306204A (en) Pure natural spirulina polypeptide mask and preparation method thereof
WO2022198771A1 (en) Composition containing animal placental exosomes, preparation method therefor and use thereof
CN111481476A (en) Potato facial mask with multiple skin care effects and preparation method thereof
WO2022088285A1 (en) Preparation method for silk fibroin facial mask solution
KR102331133B1 (en) Amino Bio-Solution and Method of Manufacturing the Same

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20180306