CN107536756B - Prickly heat removing skin care cream and preparation method thereof - Google Patents

Prickly heat removing skin care cream and preparation method thereof Download PDF

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CN107536756B
CN107536756B CN201710799299.5A CN201710799299A CN107536756B CN 107536756 B CN107536756 B CN 107536756B CN 201710799299 A CN201710799299 A CN 201710799299A CN 107536756 B CN107536756 B CN 107536756B
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care cream
removing skin
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hyaluronic acid
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CN107536756A (en
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黄冰燃
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Pingyu Iceking Biological Engineering Co.,Ltd.
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Pingyu Maya Bioengineering Co ltd
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Abstract

The invention discloses prickly heat removing skin care cream which is prepared from the following raw materials in percentage by weight: 15-25% of porous modified starch, 2-6% of wild chrysanthemum flower extract, 2-6% of radix sophorae flavescentis extract, 2-6% of folium artemisiae argyi extract, 3-5% of glycerol, 3-5% of propylene glycol, 0.5-1.5% of shea butter, 0.1-0.2% of hyaluronic acid, 0.2-0.4% of menthol lactate, 0.5-1.0% of stearic acid, 0.5-1.0% of cetearyl alcohol, 0.2-0.4% of xanthan gum, 0.3-0.4% of DMDM hydantoin, 0.05-0.1% of essence, 1.5-3.0% of emulsifier and the balance of deionized water; the invention also discloses a preparation method of the miliaria-removing skin-care cream. The invention utilizes the porous modified starch to absorb sweat on the surface of the skin, keeps the skin dry and comfortable, effectively inhibits and prevents superficial and inflammatory dermatosis caused by high temperature, and has good miliaria-removing and itching-relieving effects.

Description

Prickly heat removing skin care cream and preparation method thereof
Technical Field
The invention belongs to the technical field of daily necessities, and particularly relates to miliaria-removing skin-care cream and a preparation method thereof.
Background
In recent years, with the improvement of living standard, the natural environment is inevitably destroyed, the temperature of the whole natural environment is continuously increased due to greenhouse effect, superficial and inflammatory skin diseases (commonly called miliaria) caused by high temperature of infants in summer are more and more commonly generated, and a large amount of sweat is not easy to evaporate in a high-temperature muggy environment, so that the cuticle is soaked and swollen, a sweat gland duct is narrowed or blocked, the sweat is retained, the sweat infiltrates peripheral tissues, and papules, blisters or pustules are formed.
The prickly heat removing products in the market are mainly divided into talcum powder and prickly heat powder, the powdery prickly heat removing product contains more chemical components, dust is easy to fly when the powdery prickly heat removing product is used, and part of the powdery prickly heat removing product enters the nose and eyes and respiratory tracts of infants to easily cause allergy. The defects of the traditional prickly heat powder are more and more discovered, and a safe and effective novel preparation is urgently needed to replace the traditional prickly heat powder in the market.
Disclosure of Invention
Based on the defects of the prior art, the invention aims to provide the prickly heat removing skin care cream which is suitable for infants, safe, effective and convenient to use.
The invention also discloses a preparation method of the miliaria-removing skin-care cream.
In order to achieve the purpose, the invention adopts the technical scheme that:
the miliaria-removing skin-care cream is prepared from the following raw materials in percentage by weight: 15-25% of porous modified starch, 2-6% of wild chrysanthemum flower extract, 2-6% of radix sophorae flavescentis extract, 2-6% of folium artemisiae argyi extract, 3-5% of glycerol, 3-5% of propylene glycol, 0.5-1.5% of shea butter, 0.1-0.2% of hyaluronic acid, 0.2-0.4% of menthol lactate, 0.5-1.0% of stearic acid, 0.5-1.0% of cetearyl alcohol, 0.2-0.4% of xanthan gum, 0.3-0.4% of DMDM hydantoin, 0.05-0.1% of essence, 1.5-3.0% of emulsifier and the balance of deionized water.
Preferably, the miliaria-removing skin-care cream is prepared from the following raw materials in percentage by weight: 20% of porous modified starch, 4% of wild chrysanthemum flower extract, 4% of radix sophorae flavescentis extract, 4% of folium artemisiae argyi extract, 4% of glycerol, 4% of propylene glycol, 1.0% of shea butter, 0.1% of hyaluronic acid, 0.3% of menthol lactate, 1% of stearic acid, 1% of cetearyl alcohol, 0.3% of xanthan gum, 0.4% of DMDM hydantoin, 0.05% of essence, 2.0% of emulsifier and the balance of deionized water.
Further, the emulsifier is liquid crystal emulsifier Lipomulse Luxe (containing cetearyl alcohol, glyceryl stearate, PEG-40 stearate and ceteareth-20).
The preparation method of the miliaria-removing skin-care cream is characterized by comprising the following steps:
(1) weighing the raw materials according to the weight percentage; dissolving hyaluronic acid in a proper amount of deionized water to obtain a hyaluronic acid aqueous solution; dispersing xanthan gum in propylene glycol to obtain dispersion of xanthan gum;
(2) adding the dispersion liquid of xanthan gum, the wild chrysanthemum flower extracting solution, the radix sophorae flavescentis extracting solution and the folium artemisiae argyi extracting solution obtained in the step (1) into the balance of deionized water under the stirring condition, heating to 75-85 ℃, and uniformly mixing to obtain a water phase material;
(3) heating glycerin, shea butter, stearic acid, cetostearyl alcohol, menthol lactate and an emulsifier to 80-90 ℃ under the condition of stirring, and uniformly mixing to obtain an oil phase material;
(4) and (3) adding the water phase prepared material obtained in the step (2) into the oil phase prepared material obtained in the step (3) under the condition of stirring, cooling to 45-55 ℃, adding DMDM hydantoin, essence and the hyaluronic acid aqueous solution obtained in the step (1), cooling to below 45 ℃, adding porous modified starch, uniformly mixing, and cooling to room temperature to obtain the hyaluronic acid.
The raw materials are all common commercial products.
The flos Chrysanthemi Indici extractive solution has antiinflammatory, antioxidant, detumescence and analgesic effects. The radix sophorae flavescentis extracting solution has the effects of clearing heat, drying dampness and killing insects, can kill insects and relieve itching, has a good relieving effect on skin pruritus, can balance grease secretion, dredge and astringe pores, remove toxin impurities in skin, promote growth and repair of damaged vascular nerve cells, recover activity of subcutaneous capillary cells, and enable skin to be compact, fine and smooth, thereby playing a role in beautifying and protecting skin. The folium artemisiae argyi extract has the active effects of promoting skin collagen generation, resisting oxidation and removing free radicals, and also has the effects of moisturizing, resisting allergy and the like. The shea butter has effects of promoting cell regeneration and repairing skin water membrane, and can soften and relieve skin.
The infant skin care liquid adopts the porous modified starch to add the components of the wild chrysanthemum flower extract, the radix sophorae flavescentis extract, the folium artemisiae argyi extract, the shea butter, the hyaluronic acid, the menthol lactate and the like, is mild and fresh, absorbs sweat on the surface of the skin by utilizing the high oil absorption and water absorption characteristics of the porous modified starch, keeps the skin of an infant dry and comfortable, effectively inhibits and prevents superficial and inflammatory skin diseases (commonly called miliaria) caused by high temperature, has good miliaria-removing and itching-relieving effects, and also has good effect on mosquito bites.
Detailed Description
In order to make the technical purpose, technical solutions and advantages of the present invention clearer, the technical solutions of the present invention are further described with reference to specific examples, which are intended to explain the present invention and are not to be construed as limiting the present invention, and those who do not specify a specific technique or condition in the examples follow the techniques or conditions described in the literature in the art or follow the product specification.
The porous modified starches described in the examples below were purchased from chemical industries, Inc., Koixin, Guangzhou; the wild chrysanthemum flower extract, the radix sophorae flavescentis extract and the folium artemisiae argyi extract are all purchased from Huzhou Zhenlu biological products, Inc.; the shea butter and the hyaluronic acid are purchased from Shanghai Hengzhi investment company Limited; the menthol lactate, Guangzhou Density chemical Co., Ltd; stearic acid was purchased from Shanghai xian Kemao Co., Ltd; cetearyl alcohol was purchased from Dermax corporation, supra (16-18 alcohols); xanthan gum was purchased from shanghai kuntgen chemical ltd (xanthan gum H); DMDM hydantoin was purchased from kyoto benuojie constant scientific trade, ltd (GPL); emulsifiers were purchased from Xinnao Jiujiuxing Komao, Beijing (Lipomulse Luxe).
Example 1
The miliaria-removing skin-care cream is prepared from the following raw materials in percentage by weight: 20% of porous modified starch, 4% of wild chrysanthemum flower extracting solution, 4% of radix sophorae flavescentis extracting solution, 4% of folium artemisiae argyi extracting solution, 4% of glycerol, 4% of propylene glycol, 1.0% of shea butter, 0.1% of hyaluronic acid, 0.3% of menthol lactate, 1% of stearic acid, 1% of cetostearyl alcohol, 0.3% of xanthan gum, 0.4% of DMDM hydantoin, 0.05% of essence, 2.0% of emulsifier (Lipomule Luxe), and the balance of deionized water.
Example 2
The miliaria-removing skin-care cream is prepared from the following raw materials in percentage by weight: 15% of porous modified starch, 2% of wild chrysanthemum flower extract, 2% of radix sophorae flavescentis extract, 2% of folium artemisiae argyi extract, 3% of glycerol, 3% of propylene glycol, 0.5% of shea butter, 0.1% of hyaluronic acid, 0.2% of menthol lactate, 1% of stearic acid, 1% of cetostearyl alcohol, 0.2% of xanthan gum, 0.4% of DMDM hydantoin, 0.05% of essence, 1.5% of emulsifier (Lipomule Luxe), and the balance of deionized water.
Example 3
The miliaria-removing skin-care cream is prepared from the following raw materials in percentage by weight: 25% of porous modified starch, 6% of wild chrysanthemum flower extracting solution, 6% of radix sophorae flavescentis extracting solution, 6% of folium artemisiae argyi extracting solution, 5% of glycerol, 5% of propylene glycol, 1.5% of shea butter, 0.1% of hyaluronic acid, 0.4% of menthol lactate, 1% of stearic acid, 1% of cetostearyl alcohol, 0.4% of xanthan gum, 0.4% of DMDM hydantoin, 0.05% of essence, 3.0% of emulsifier (Lipomule Luxe), and the balance of deionized water.
The miliaria-removing skin care cream disclosed in the embodiment 1-3 is prepared by the following steps:
(1) weighing the raw materials according to the weight percentage; dissolving hyaluronic acid in a proper amount of deionized water to obtain a hyaluronic acid aqueous solution; dispersing xanthan gum in propylene glycol to obtain dispersion of xanthan gum;
(2) adding the dispersion liquid of xanthan gum obtained in the step (1), the wild chrysanthemum flower extracting solution, the radix sophorae flavescentis extracting solution, the folium artemisiae argyi extracting solution and the balance of deionized water into a water pot under the condition of stirring, heating to 80 ℃, and uniformly mixing to obtain a water phase material;
(3) adding glycerol, shea butter, stearic acid, cetostearyl alcohol, menthol lactate and emulsifier (Lipomulse Luxe) into an oil pan under stirring, heating to 85 deg.C, and mixing to obtain oil phase;
(4) pumping the oil phase prepared material obtained in the step (2) into an emulsifying pot, adding the water phase prepared material obtained in the step (1) under the stirring condition, cooling to 50 ℃, adding DMDM hydantoin, essence and the hyaluronic acid aqueous solution obtained in the step (1), cooling to below 45 ℃, adding porous modified starch, uniformly mixing and cooling to room temperature to obtain the hyaluronic acid.
Effect test
1. Miliaria-removing and itching-relieving test
50 volunteers with miliaria, 1-5 years old, were selected for testing using inventive example 1.
The determination method comprises the following steps: the miliaria-removing skin care cream obtained in example 1 is uniformly applied to an affected part twice a day for five consecutive days, and the using effect is examined.
As a result: the medicine can obviously relieve itching and relieve miliaria when used on the first day; 43 volunteers completely dispel miliaria on the third day, and on the fifth day, the volunteers completely dispel miliaria.
2. Evaluation of safety
The miliaria-removing skin care cream disclosed in the embodiment 1-3 is used for carrying out a skin irritation test, an allergic test and an acute eye irritation test, and the results are as follows: (1) skin irritation test: the subjects in the miliaria-removing and itching-relieving test have no irritation in the test process, and do not have systemic or local adverse reactions. (2) Skin allergy test: 30 healthy children volunteers are selected, the age is 2-4 years, the healthy children volunteers are divided into 3 groups, 10 people in each group are tested after the prickly heat removing skin care cream disclosed in the embodiment 1-3 is used according to the specification, the period is one month, and the result proves that the prickly heat removing skin care cream has no sensitivity to human skin basically. (3) Acute eye irritation test: the results of domestic mouse and animal experiments according to relevant national regulations prove that the miliaria-removing skin care cream disclosed in the examples 1-3 has no stimulation to eyes. Therefore, the miliaria-removing skin care cream provided by the invention has no stimulation to a human body, is high in safety, and can be used by adults and infants.
3. Stability test
The miliaria-removing skin care cream disclosed by the embodiment 1-3 is subjected to a long-term indoor sample retention test and a heat storage stability test, and still has no color change and no change of cream quality after being placed for 36 months under the conditions of 20 ℃ and humidity of 55 +/-5%; the color and the paste quality are not changed after the paste is placed for 10 months under the conditions of 45 ℃ and the humidity of 55 +/-5 percent.

Claims (3)

1. The preparation method of the miliaria-removing skin-care cream is characterized in that the miliaria-removing skin-care cream is prepared from the following raw materials in percentage by weight: 15-25% of porous modified starch, 2-6% of wild chrysanthemum flower extract, 2-6% of radix sophorae flavescentis extract, 2-6% of folium artemisiae argyi extract, 3-5% of glycerol, 3-5% of propylene glycol, 0.5-1.5% of shea butter, 0.1-0.2% of hyaluronic acid, 0.2-0.4% of menthol lactate, 0.5-1.0% of stearic acid, 0.5-1.0% of cetearyl alcohol, 0.2-0.4% of xanthan gum, 0.3-0.4% of DMDM hydantoin, 0.05-0.1% of essence, 1.5-3.0% of emulsifier and the balance of deionized water;
the preparation method of the miliaria-removing skin-care cream comprises the following steps:
(1) weighing the raw materials according to the weight percentage; dissolving hyaluronic acid in a proper amount of deionized water to obtain a hyaluronic acid aqueous solution; dispersing xanthan gum in propylene glycol to obtain dispersion of xanthan gum;
(2) adding the dispersion liquid of xanthan gum, the wild chrysanthemum flower extracting solution, the radix sophorae flavescentis extracting solution and the folium artemisiae argyi extracting solution obtained in the step (1) into the balance of deionized water under the stirring condition, heating to 75-85 ℃, and uniformly mixing to obtain a water phase material;
(3) heating glycerin, shea butter, stearic acid, cetostearyl alcohol, menthol lactate and an emulsifier to 80-90 ℃ under the condition of stirring, and uniformly mixing to obtain an oil phase material;
(4) and (3) adding the water phase prepared material obtained in the step (2) into the oil phase prepared material obtained in the step (3) under the condition of stirring, cooling to 45-55 ℃, adding DMDM hydantoin, essence and the hyaluronic acid aqueous solution obtained in the step (1), cooling to below 45 ℃, adding porous modified starch, uniformly mixing, and cooling to room temperature to obtain the hyaluronic acid.
2. The preparation method of the miliaria-removing skin care cream according to claim 1, wherein the miliaria-removing skin care cream is prepared from the following raw materials in percentage by weight: 20% of porous modified starch, 4% of wild chrysanthemum flower extract, 4% of radix sophorae flavescentis extract, 4% of folium artemisiae argyi extract, 4% of glycerol, 4% of propylene glycol, 1.0% of shea butter, 0.1% of hyaluronic acid, 0.3% of menthol lactate, 1% of stearic acid, 1% of cetearyl alcohol, 0.3% of xanthan gum, 0.4% of DMDM hydantoin, 0.05% of essence, 2.0% of emulsifier and the balance of deionized water.
3. The preparation method of the miliaria-removing skin care cream according to claim 1 or 2, wherein the prickly heat-removing skin care cream comprises the following steps: the emulsifier is a liquid crystal emulsifier Lipomulse Luxe.
CN201710799299.5A 2017-09-07 2017-09-07 Prickly heat removing skin care cream and preparation method thereof Active CN107536756B (en)

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CN108403575A (en) * 2018-06-11 2018-08-17 广州三亮科技有限公司 A kind of baby's treasured cold cream
CN110960454B (en) * 2019-11-29 2022-03-18 克劳丽化妆品股份有限公司 Chrysanthemum morifolium extract liposome and preparation method and application thereof

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