CN107536756A - One kind is dispelled miliaria cold cream and preparation method thereof - Google Patents

One kind is dispelled miliaria cold cream and preparation method thereof Download PDF

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Publication number
CN107536756A
CN107536756A CN201710799299.5A CN201710799299A CN107536756A CN 107536756 A CN107536756 A CN 107536756A CN 201710799299 A CN201710799299 A CN 201710799299A CN 107536756 A CN107536756 A CN 107536756A
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miliaria
cold cream
extractive liquid
xanthan gum
emulsifying agent
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CN201710799299.5A
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CN107536756B (en
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黄冰燃
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Pingyu Iceking Biological Engineering Co.,Ltd.
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Pingyu Maya Biological Engineering Co Ltd
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Abstract

Dispel miliaria cold cream the invention discloses one kind, be made up of the raw material of following weight percentage:More bore deformation starch 15 ~ 25%, chrysanthemum indicum extract solution 2 ~ 6%, Radix Sophorae Flavescentis extractive liquid 2 ~ 6%, Folium Artemisiae Argyi extractive liquid 2 ~ 6%, glycerine 3 ~ 5%, propane diols 3 ~ 5%, shea butter 0.5 ~ 1.5%, hyaluronic acid 0.1 ~ 0.2%, menthanol lactic acid ester 0.2 ~ 0.4%, stearic acid 0.5 ~ 1.0%, cetostearyl alcohol 0.5 ~ 1.0%, xanthan gum 0.2 ~ 0.4%, DMDMH 0.3 ~ 0.4%, essence 0.05 ~ 0.1%, emulsifying agent 1.5 ~ 3.0%, surplus are deionized water;The invention also discloses the preparation method of the miliaria cold cream of dispelling.It is of the invention to absorb skin surface sweat using porous converted starch, skin is kept dry and comfortable, the shallow property of table, inflammatory dermatoses effectively caused by suppression and pre- high temperature-proof, there is good removing miliaria and relieving itching effect.

Description

One kind is dispelled miliaria cold cream and preparation method thereof
Technical field
The invention belongs to small stores technical field, and in particular to one kind is dispelled miliaria cold cream and preparation method thereof.
Background technology
In recent years, inevitably destroyed along with growth in the living standard, natural environment, greenhouse effects generate Improve constantly to whole natural environment temperature, infant is in the shallow property of table caused by summer high temperature, inflammatory dermatoses(It is commonly called as miliaria Son)More and more common generation, because under the sultry environment of high temperature, substantial amounts of sweat is not easy to evaporate, cuticula is set to impregnate swelling, sweat Gland conduit narrows or blocked, and causes sweat retention, sweat extravasation surrounding tissue, forms papule, blister or warts.
Miliaria product of dispelling currently on the market is roughly divided into talcum powder, prickly-heat powder, silty dispel miliaria product containing chemical composition compared with It is more, and silty dispels miliaria product when in use, easily causes dust from flying, portioned product enters nose eye and the breathing of infant Road, easily cause allergy.The defects of traditional prickly-heat powder, is more and more found, and in the market is badly in need of a kind of safely and effectively new Type preparation substitutes traditional prickly-heat powder.
The content of the invention
Based on the deficiencies in the prior art, object of the present invention is to provide the miliaria skin care of dispelling that a kind of suitable infant uses Cream, it is safe and effective, easy to use.
The invention also discloses the preparation method of the miliaria cold cream of dispelling.
To achieve these goals, the technical solution adopted by the present invention is:
One kind is dispelled miliaria cold cream, is made up of the raw material of following weight percentage:More bore deformation starch 15 ~ 25%, chrysanthemum indicum extract solution 2 ~ 6%, Radix Sophorae Flavescentis extractive liquid 2 ~ 6%, Folium Artemisiae Argyi extractive liquid 2 ~ 6%, glycerine 3 ~ 5%, propane diols 3 ~ 5%, shea butter 0.5 ~ 1.5%, transparent Matter acid 0.1 ~ 0.2%, menthanol lactic acid ester 0.2 ~ 0.4%, stearic acid 0.5 ~ 1.0%, cetostearyl alcohol 0.5 ~ 1.0%, xanthan gum 0.2 ~ 0.4%, DMDM hydantoins 0.3 ~ 0.4%, essence 0.05 ~ 0.1%, emulsifying agent 1.5-3.0%, surplus are deionized water.
Preferably, the miliaria cold cream of dispelling, is made up of the raw material of following weight percentage:More bore deformation starch 20%, mother chrysanthemum Flower extract solution 4%, Radix Sophorae Flavescentis extractive liquid 4%, Folium Artemisiae Argyi extractive liquid 4%, glycerine 4%, propane diols 4%, shea butter 1.0%, hyaluronic acid 0.1%th, menthanol lactic acid ester 0.3%, stearic acid 1%, cetostearyl alcohol 1%, xanthan gum 0.3%, DMDM hydantoins 0.4%, essence 0.05%th, emulsifying agent 2.0%, surplus are deionized water.
Further, the emulsifying agent is liquid crystal type emulsifying agent Lipomulse Luxe(Contain cetostearyl alcohol, glyceryl stearate Acid esters, PEG-40 stearates and ceteareth -20).
The preparation method of above-mentioned miliaria cold cream of dispelling, it is characterised in that comprise the following steps:
(1)Each raw material is weighed by weight percentage;Take appropriate deionized water to dissolve hyaluronic acid, obtain the water of hyaluronic acid Solution;Xanthan gum is scattered in propane diols, obtains the dispersion liquid of xanthan gum;
(2)Under agitation, by step(1)The dispersion liquid of gained xanthan gum, chrysanthemum indicum extract solution, Radix Sophorae Flavescentis extractive liquid, folium artemisiae argyi Extract solution is added in the deionized water of surplus, is heated to 75 ~ 85 DEG C, is mixed, and obtains aqueous phase stock;
(3)Under agitation, glycerine, shea butter, stearic acid, cetostearyl alcohol, menthanol lactic acid ester and emulsifying agent are added Heat mixes to 80 ~ 90 DEG C, obtains oil phase stock;
(4)Under agitation, by step(2)Gained aqueous phase stock adds step(3)Gained oil phase is stocked up, and is cooled to 45 ~ 55 DEG C, add DMDM hydantoins, essence, step(1)The aqueous solution of gained hyaluronic acid, treat that temperature is down to less than 45 DEG C, then add Enter more bore deformation starch, mix and be cooled to room temperature, produce.
Above-mentioned raw materials are ordinary commercial products.
The chrysanthemum indicum extract solution has anti-inflammatory, anti-oxidant, Repercusion analgesia activity.The Radix Sophorae Flavescentis extractive liquid has heat-clearing dry Wet, the effect of desinsection, and desinsection is antipruritic, there is good mitigation to pruitus, additionally it is possible to Bergamot Mint Extract, dredging And pore is restrained, skin endotoxin contamination is removed, promotes the growth and reparation of damaged blood vessels nerve cell, recovers subcutaneous blood capillary Solencyte vigor, skin, which reappears, to compact fine and smooth, plays a part of beauty and skin care.The Folium Artemisiae Argyi extractive liquid, which has, promotes skin collagen Albumen generation, active effect that is anti-oxidant, removing free radical, also with moisturizing, antiallergy and other effects.The shea butter has The effect of promoting cytothesis and repairing skin moisture film, can be with tender, skin of releiving.
The present invention is using porous converted starch addition chrysanthemum indicum extract solution, Radix Sophorae Flavescentis extractive liquid, Folium Artemisiae Argyi extractive liquid, the wooden fruit of breast The compositions such as oil, hyaluronic acid, menthanol lactic acid ester, it is gentle pure and fresh, using the high oil absorption water absorption character of more space-variant starch, absorb The sweat of skin surface, infant's skin is set to keep dry and comfortable, the shallow property of table, inflammatory skin effectively caused by suppression and pre- high temperature-proof Disease(It is commonly called as prickly heat), have good removing miliaria and relieving itching effect, also there is good effect to bite by mosquitos.
Embodiment
In order that the technical purpose of the present invention, technical scheme and beneficial effect are clearer, with reference to specific embodiment Technical scheme is further illustrated, but the embodiment is intended to explain the present invention, and it is not intended that right The limitation of the present invention, in the examples where no specific technique or condition is specified, according to the technology described by document in the art or Condition is carried out according to product description.
More bore deformation starch described in following embodiments believe Chemical Co., Ltd. purchased from Guangzhou Coe;The chrysanthemum indicum extraction Liquid, Radix Sophorae Flavescentis extractive liquid and Folium Artemisiae Argyi extractive liquid are purchased from Huzhou Zhenlu Biological Products Co., Ltd.;The shea butter and hyalomitome Acid is purchased from Shanghai Heng Cui Investment Co., Ltd;The menthanol lactic acid ester Guangzhou Ding Du Chemical Co., Ltd.s;Stearic acid is purchased from Shanghai Xian En scientific & trading Co., Ltd.s;Cetostearyl alcohol is purchased from upper marine Dehua work Co., Ltd(16 ~ 18 alcohol);Xanthan gum is purchased from upper Hai Fang steps on Chemical Co., Ltd.(Xanthan gum H);DMDM hydantoins is purchased from Jiu Heng scientific & trading Co., Ltd.s of Beijing Cigna(GPL);Breast Agent is purchased from Jiu Heng scientific & trading Co., Ltd.s of Beijing Cigna(Lipomulse Luxe).
Embodiment 1
One kind is dispelled miliaria cold cream, is made up of the raw material of following weight percentage:Porous converted starch 20%, chrysanthemum indicum extract solution 4%, Radix Sophorae Flavescentis extractive liquid 4%, Folium Artemisiae Argyi extractive liquid 4%, glycerine 4%, propane diols 4%, shea butter 1.0%, hyaluronic acid 0.1%, menthol breast Acid esters 0.3%, stearic acid 1%, cetostearyl alcohol 1%, xanthan gum 0.3%, DMDM hydantoins 0.4%, essence 0.05%, emulsifying agent (Lipomulse Luxe)2.0%, surplus is deionized water.
Embodiment 2
One kind is dispelled miliaria cold cream, is made up of the raw material of following weight percentage:Porous converted starch 15%, chrysanthemum indicum extract solution 2%, Radix Sophorae Flavescentis extractive liquid 2%, Folium Artemisiae Argyi extractive liquid 2%, glycerine 3%, propane diols 3%, shea butter 0.5%, hyaluronic acid 0.1%, menthol breast Acid esters 0.2%, stearic acid 1%, cetostearyl alcohol 1%, xanthan gum 0.2%, DMDM hydantoins 0.4%, essence 0.05%, emulsifying agent (Lipomulse Luxe)1.5%, surplus is deionized water.
Embodiment 3
One kind is dispelled miliaria cold cream, is made up of the raw material of following weight percentage:Porous converted starch 25%, chrysanthemum indicum extract solution 6%, Radix Sophorae Flavescentis extractive liquid 6%, Folium Artemisiae Argyi extractive liquid 6%, glycerine 5%, propane diols 5%, shea butter 1.5%, hyaluronic acid 0.1%, menthol breast Acid esters 0.4%, stearic acid 1%, cetostearyl alcohol 1%, xanthan gum 0.4%, DMDM hydantoins 0.4%, essence 0.05%, emulsifying agent (Lipomulse Luxe)3.0%, surplus is deionized water.
Miliaria cold cream of being dispelled described in embodiment 1 ~ 3 is prepared using following steps:
(1)Each raw material is weighed by weight percentage;Take appropriate deionized water to dissolve hyaluronic acid, obtain the water of hyaluronic acid Solution;Xanthan gum is scattered in propane diols, obtains the dispersion liquid of xanthan gum;
(2)Under agitation, by step(1)The dispersion liquid of gained xanthan gum, chrysanthemum indicum extract solution, Radix Sophorae Flavescentis extractive liquid, folium artemisiae argyi The deionized water of extract solution and surplus is added in kettle, is heated to 80 DEG C, is mixed, and obtains aqueous phase stock;
(3)Under agitation, by glycerine, shea butter, stearic acid, cetostearyl alcohol, menthanol lactic acid ester and emulsifying agent (Lipomulse Luxe)Add in oil cauldron, be heated to 85 DEG C, mix, obtain oil phase stock;
(4)By step(2)Gained oil phase stock is pumped into emulsification pot, under agitation, adds step(1)Gained aqueous phase is standby Material, 50 DEG C are cooled to, add DMDM hydantoins, essence, step(1)The aqueous solution of gained hyaluronic acid, treat that temperature is down to 45 Below DEG C, more bore deformation starch are added, mixes and is cooled to room temperature, produce.
Effect experiment
1. removing miliaria and relieving itching is tested
50 volunteers for suffering from prickly heat of selection, at 1 years old ~ 5 years old age, are tested using the embodiment of the present invention 1.
Assay method:Miliaria cold cream of being dispelled obtained by embodiment 1 is uniformly applied to affected part, twice daily, is used continuously five days, Investigate using effect.
As a result:Use in first day can be substantially antipruritic, alleviates prickly heat;There are within 3rd day 43 volunteers to dispel completely miliaria, the 5th day The miliaria so volunteer dispels completely.
2. safety evaluatio
Miliaria cold cream of being dispelled described in Example 1 ~ 3 carries out Skin Irritation Test, sensitivity test and acute eye irritation test, knot Fruit is as follows:(1)Skin irritation test:Subject in above-mentioned removing miliaria and relieving itching experiment is nonirritant during experiment, It there are no whole body or local adverse reaction.(2)Skin allergy test:The people of healthy infants volunteer 30 is selected, the age was at 2 ~ 4 years old Between, it is divided into 3 groups, every group of 10 people, is tested after using according to regulations miliaria cold cream of being dispelled described in embodiment 1 ~ 3, the cycle is one Month, as a result prove the present invention to human body skin substantially without sensitization.(3)Acute eye irritation test:Carry out according to the pertinent regulations of state Family's small white mouse animal experiment, miliaria cold cream of as a result being dispelled described in proof embodiment 1 ~ 3 are non-stimulated to eyes.As can be seen here, this hair Bright offer dispels that miliaria cold cream is non-stimulated to human body, and its is safe, and adult and infant can be used.
3. stability test
The long-term interior of miliaria cold cream of being dispelled described in Example 1 ~ 3 progress keeps sample to test tests with heat storage stability, in 20 DEG C, humidity It is still unchanged without color change, cream matter after being placed 36 months under conditions of 55 ± 5%;Under conditions of 45 DEG C, humidity 55 ± 5% Place 10 months it is unchanged without color change, cream matter.

Claims (4)

  1. The miliaria cold cream 1. one kind is dispelled, it is characterised in that be made up of the raw material of following weight percentage:More bore deformation starch 15 ~ 25%th, chrysanthemum indicum extract solution 2 ~ 6%, Radix Sophorae Flavescentis extractive liquid 2 ~ 6%, Folium Artemisiae Argyi extractive liquid 2 ~ 6%, glycerine 3 ~ 5%, propane diols 3 ~ 5%, the wooden fruit of breast Oil 0.5 ~ 1.5%, hyaluronic acid 0.1 ~ 0.2%, menthanol lactic acid ester 0.2 ~ 0.4%, stearic acid 0.5 ~ 1.0%, cetostearyl alcohol 0.5 ~ 1.0%, xanthan gum 0.2 ~ 0.4%, DMDM hydantoins 0.3 ~ 0.4%, essence 0.05 ~ 0.1%, emulsifying agent 1.5 ~ 3.0%, surplus For deionized water.
  2. 2. miliaria cold cream according to claim 1 of dispelling, it is characterised in that be made up of the raw material of following weight percentage:It is more Bore deformation starch 20%, chrysanthemum indicum extract solution 4%, Radix Sophorae Flavescentis extractive liquid 4%, Folium Artemisiae Argyi extractive liquid 4%, glycerine 4%, propane diols 4%, the wooden fruit of breast Oil 1.0%, hyaluronic acid 0.1%, menthanol lactic acid ester 0.3%, stearic acid 1%, cetostearyl alcohol 1%, xanthan gum 0.3%, DMDM second Interior uride 0.4%, essence 0.05%, emulsifying agent 2.0%, surplus are deionized water.
  3. 3. miliaria cold cream according to claim 1 or 2 of dispelling, it is characterised in that:The emulsifying agent is liquid crystal type emulsifying agent Lipomulse Luxe。
  4. 4. the preparation method for miliaria cold cream of being dispelled described in claim 3, it is characterised in that comprise the following steps:
    (1)Each raw material is weighed by weight percentage;Take appropriate deionized water to dissolve hyaluronic acid, obtain the water of hyaluronic acid Solution;Xanthan gum is scattered in propane diols, obtains the dispersion liquid of xanthan gum;
    (2)Under agitation, by step(1)The dispersion liquid of gained xanthan gum, chrysanthemum indicum extract solution, Radix Sophorae Flavescentis extractive liquid, folium artemisiae argyi Extract solution is added in the deionized water of surplus, is heated to 75 ~ 85 DEG C, is mixed, and obtains aqueous phase stock;
    (3)Under agitation, glycerine, shea butter, stearic acid, cetostearyl alcohol, menthanol lactic acid ester and emulsifying agent are added Heat mixes to 80 ~ 90 DEG C, obtains oil phase stock;
    (4)Under agitation, by step(2)Gained aqueous phase stock adds step(3)Gained oil phase is stocked up, and is cooled to 45 ~ 55 DEG C, add DMDM hydantoins, essence, step(1)The aqueous solution of gained hyaluronic acid, treat that temperature is down to less than 45 DEG C, then add Enter more bore deformation starch, mix and be cooled to room temperature, produce.
CN201710799299.5A 2017-09-07 2017-09-07 Prickly heat removing skin care cream and preparation method thereof Active CN107536756B (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108403575A (en) * 2018-06-11 2018-08-17 广州三亮科技有限公司 A kind of baby's treasured cold cream
CN110960454A (en) * 2019-11-29 2020-04-07 苏州克劳丽化妆品有限公司 Chrysanthemum morifolium extract liposome and preparation method and application thereof

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CN102406555A (en) * 2011-09-13 2012-04-11 海南建科药业有限公司 Microporous starch talcum powder
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CN105395593A (en) * 2015-12-09 2016-03-16 广州赛莱拉生物基因工程有限公司 Itching relieving ointment containing folium artemisiae argyi extract and preparation method thereof

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Cited By (3)

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Publication number Priority date Publication date Assignee Title
CN108403575A (en) * 2018-06-11 2018-08-17 广州三亮科技有限公司 A kind of baby's treasured cold cream
CN110960454A (en) * 2019-11-29 2020-04-07 苏州克劳丽化妆品有限公司 Chrysanthemum morifolium extract liposome and preparation method and application thereof
CN110960454B (en) * 2019-11-29 2022-03-18 克劳丽化妆品股份有限公司 Chrysanthemum morifolium extract liposome and preparation method and application thereof

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