CN107496823A - A kind of radix polygonati officinalis rhizoma polygonati cream and preparation method thereof - Google Patents
A kind of radix polygonati officinalis rhizoma polygonati cream and preparation method thereof Download PDFInfo
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- CN107496823A CN107496823A CN201710945132.5A CN201710945132A CN107496823A CN 107496823 A CN107496823 A CN 107496823A CN 201710945132 A CN201710945132 A CN 201710945132A CN 107496823 A CN107496823 A CN 107496823A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8969—Polygonatum (Solomon's seal)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9064—Amomum, e.g. round cardamom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Abstract
The invention discloses a kind of radix polygonati officinalis rhizoma polygonati cream and preparation method thereof, the raw material of the radix polygonati officinalis rhizoma polygonati cream includes by weight：90~110 parts of radix polygonati officinalis, steam 90~110 parts of sealwort, 140~160 parts of Chinese yam, 140~160 parts of jujube, 90~110 parts of the fruit of Chinese wolfberry, 90~110 parts of Poria cocos, 90~110 parts of mulberry fruit, 90~110 parts of black soybean, 40~60 parts of fructus amomi, 40~60 parts of donkey-hide gelatin, 100~140 parts of xylitol, 200~280 parts of oligoisomaltose, 0.4~0.6 part of potassium sorbate, 0.1~0.14 part of tartaric acid.The radix polygonati officinalis rhizoma polygonati cream of the present invention has no toxic side effect and adverse reaction, and can replenish qi to invigorate the spleen blood-nourishing, filling liver kidney, cures women Qi and blood deficiency, the deficiency of liver-yin and kidney-yin.
Description
Technical field
The present invention relates to field of traditional Chinese, and in particular to a kind of radix polygonati officinalis rhizoma polygonati cream and preparation method thereof.
Background technology
The deficiency of vital energy, refer in poor health, pale complexion, short of breath, limbs fatigue, dizziness, dynamic then sweating, faint low voice
Deng, it includes vigour, pectoral qi, defends the deficient of gas, and the promotion of gas, warm, defence, takes the photograph decline with gasification function admittedly, from
And cause some functional activities of body low or fail, the weak phenomenons such as resistance against diseases declines.The vital movement of people is from root
Say to be exactly that vigour lifts the motion to come in and go out in sheet.The deficiency of vital energy is that one kind is issued licence more, more because inadequate natural endowment, malnutrition, it is old weak,
Prolonged illness is not cured, after major operation and excessive fatigue.
The deficiency of blood refers to the pathological phenomenon of cloudy anemia damage in vivo, can be consumed by excessive blood loss, or prolonged illness the moon deficiency of blood, or spleen and stomach function loses
Often, essence of water and grain is unable to caused by metaplasia blood etc..Because gas and blood have a substantial connection, therefore the deficiency of blood easily causes the deficiency of vital energy, and the deficiency of vital energy
Metaplasia blood is unable to, is a factor for forming the deficiency of blood again.
Modern female operating pressure is increasing, busy plus housework, and life is irregular, lacks motion etc. causes modern female
The problems such as easily there is Qi and blood deficiency and causes the deficiency of liver-yin and kidney-yin, visual impairment in property.Chemicals side effect in the market and
Erious adverse reaction, and it is ineffective, therefore need a kind of blood-nourishing that replenishes qi to invigorate the spleen of research and development, the Chinese drugs agentia of filling liver kidney badly.
The content of the invention
The main object of the present invention is to provide a kind of radix polygonati officinalis rhizoma polygonati cream and preparation method thereof, it is intended to solves women Qi and blood deficiency
The problem of.
To achieve the above object, the present invention proposes a kind of radix polygonati officinalis rhizoma polygonati cream, and the raw material of the radix polygonati officinalis rhizoma polygonati cream is by weight
Meter includes：90~110 parts of radix polygonati officinalis, 90~110 parts of sealwort of steaming, 140~160 parts of Chinese yam, 140~160 parts of jujube, the fruit of Chinese wolfberry 90~
110 parts, 90~110 parts of Poria cocos, 90~110 parts of mulberry fruit, 90~110 parts of black soybean, 40~60 parts of fructus amomi, 40~60 parts of donkey-hide gelatin,
100~140 parts of xylitol, 200~280 parts of oligoisomaltose, 0.4~0.6 part of potassium sorbate, 0.1~0.14 part of tartaric acid.
In addition, the present invention also provides a kind of preparation method of radix polygonati officinalis rhizoma polygonati cream, the raw material of the radix polygonati officinalis rhizoma polygonati cream is by weight
Part meter, the preparation method comprise the following steps：
Prepare donkey-hide gelatin solution：40~60 parts of donkey-hide gelatin are crushed, molten, obtain the donkey-hide gelatin solution；
Prepare clear cream：Following raw material is added in extractor：90~110 portions of radix polygonati officinalis, 90~110 parts of steaming sealworts,
140~160 portions of Chinese yams, 140~160 portions of jujubes, 90~110 portions of fruits of Chinese wolfberry, 90~110 parts of Poria cocos, 90~110 portions of mulberry fruits, 90
~110 portions of black soybean, 40~60 parts of fructus amomis, the water immersion of 700~900 parts by weight is added, Dynamic Extraction is heated, filtering, obtains
500~700 parts by weight water are added to the first filtrate, then by filter residue, Dynamic Extraction is heated, filtering, obtains the second filtrate, merge the
One filtrate and the second filtrate, are concentrated under reduced pressure to give concentrate, the concentrate are filtrated to get into the clear cream；
Prepare xylitol solution：Take 100~140 parts by weight xylitols, 200~280 parts by weight oligoisomaltoses, 210
~300 parts by weight water, 0.1~0.14 parts by weight tartaric acid, dissolve by heating and keep micro-boiling, are stirred continuously uniformly, obtain described
Xylitol solution；
Receive cream：Take 0.4~0.6 parts by weight potassium sorbate to be dissolved in 15~25 parts by weight water, potassium sorbate solution is made,
The clear cream is poured into open-top receptacle, is heated to micro-boiling, and the xylitol solution is poured into the clear cream, adds sorbic acid
Potassium solution, micro-boiling is kept, be eventually adding the donkey-hide gelatin solution, agitating and heating, obtain cream taste, the radix polygonati officinalis sealwort is obtained after cooling
Cream.
Preferably, it is described to prepare concretely comprising the following steps for molten described in donkey-hide gelatin solution step：Donkey-hide gelatin after crushing is added
Yellow rice wine soaks, heating water bath to whole dissolvings.
Preferably, the time of the step reclaimed water immersion for preparing clear cream is 1~1.5 hour；The heating Dynamic Extraction
Heating-up temperature be 100~110 DEG C, the time be 1.5~2 hours.
Preferably, the filter cloth filtered in described the step of preparing clear cream is 80~120 mesh；The temperature that is concentrated under reduced pressure is
60~70 DEG C, vacuum is -0.06~-0.08MPa.
Preferably, the time that micro-boiling is dissolved by heating and kept in described the step of preparing xylitol solution is 1~3h.
Preferably, it is heated to be steam heating in the step of receipts cream；After the xylitol solution is poured into the clear cream,
Material cumulative volume is the 1/2~2/3 of open-top receptacle volume.
Preferably, the temperature of agitating and heating is 100~105 DEG C in described the step of receiving cream, treats that the liquid-tight degree of the cream is
During 1.26~1.27g/ml, stop heating.
Preferably, the preparation method also includes：The radix polygonati officinalis rhizoma polygonati cream is sub-packed in packing container, it is hermetically sealed.
In technical solution of the present invention, Chinese yam and jujube tonifying middle-Jiao and Qi, strengthening spleen and nourishing blood are all monarch drug in a prescription；It is aided with Poria cocos invigorating the spleen to ooze
It is wet；The fruit of Chinese wolfberry, mulberry fruit, radix polygonati officinalis, black soya bean nourishing Yin and moistening dryness, the moon to tonify the liver and kidney；Donkey-hide gelatin, black soya bean are enriched blood enriching yin；With fructus amomi aromatization
It is wet, promoting the circulation of qi appetizing；Full side is to replenish qi to invigorate the spleen, nourishing Yin and moistening dryness, blood-nourishing, dampness elimination appetizing, mend without stagnant.The invention provides a kind of nothing
Toxic side effect and adverse reaction, and can replenish qi to invigorate the spleen blood-nourishing, filling liver kidney, it is yellow to cure women Qi and blood deficiency, the radix polygonati officinalis of the deficiency of liver-yin and kidney-yin
Smart cream；Also, using glycitols and oligosaccharides etc. will not cause in blood glucose value and blood the auxiliary material of the fluctuation of insulin level and
Food additives, avoid because take produced in conventional processes cream grow the auxiliary materials such as applied honey, sugar and caused by hyperglycaemia, hair
The problems such as fat, the glycitols and oligosaccharides auxiliary material that the present invention is used, having makes cream grow relatively low heat, good mouthfeel, regulation
The features such as functions of intestines and stomach.
Embodiment
The technical scheme in the embodiment of the present invention will be clearly and completely described below, it is clear that described implementation
Example is only the part of the embodiment of the present invention, rather than whole embodiments.It is general based on the embodiment in the present invention, this area
The every other embodiment that logical technical staff is obtained under the premise of creative work is not made, belong to what the present invention protected
Scope.
In addition, the technical scheme between each embodiment of the present invention can be combined with each other, but must be general with this area
Logical technical staff can be implemented as basis, will be understood that when the combination appearance of technical scheme is conflicting or can not realize this
The combination of technical scheme is not present, also not within the protection domain of application claims.
The present invention proposes a kind of radix polygonati officinalis rhizoma polygonati cream, and raw material includes by weight：90~110 parts of radix polygonati officinalis, steaming sealwort 90~
110 parts, 140~160 parts of Chinese yam, 140~160 parts of jujube, 90~110 parts of the fruit of Chinese wolfberry, 90~110 parts of Poria cocos, mulberry fruit 90~110
Part, 90~110 parts of black soybean, 40~60 parts of fructus amomi, 40~60 parts of donkey-hide gelatin, 100~140 parts of xylitol, oligoisomaltose 200
~280 parts, 0.4~0.6 part of potassium sorbate, 0.1~0.14 part of tartaric acid.
The product that radix polygonati officinalis category nourishing Yin and keeping spirit is enriched blood, ancients claim flat mend of radix polygonati officinalis and moistened, and have the work(except wind-heat concurrently, therefore the profit that can preserve youthful looks
Skin, eliminate disease and prolong life.Radix polygonati officinalis is mended and oiliness, not cold not dry, thus have " help the five internal organs, nourish qi and blood, flat mend and moisten, it is simultaneous to remove wind-heat " it
Work(, informal dress radix polygonati officinalis can anti-aging, promote longevity.、
Sealwort sweet taste, energy Yin nourishing and lung moistening, invigorates the spleen and benefits qi, Zishen fill fine, cures mainly deficiency of Yin overstrain cough；Xeropulmonary cough；It is insufficiency of the spleen
It is weak；Few dry of food；Quench one's thirst；Deficiency of the kidney soreness and weakness of waist and knees；Impotence and seminal emission；Tinnitus mesh is dark；Poliosis；Physically weak win is thin；Wind favus disease.
Jujube energy invigorating spleen and reinforcing stomach, invigorating qi and benefiting blood, nourishing blood and tranquilization, women anxiety disorder, cry uneasy, have no peace of mind, use is red
Jujube and radix glycyrrhizae, wheat can play nourishing blood and tranquilization with using ＜ ganmai dazao decoction ＞, the effect of liver soothing and depression relief.
Fruit of Chinese wolfberry energy tonifying kidney and benefiting sperm, nourishes the liver to improve visual acuity, and blood-enriching tranquillizing, production of sperm quenches the thirst, and moistens the lung and relieve the cough.Control liver-kidney Yin deficiency, waist and knee
It is aching and limp, have a dizzy spell, the more tears of blurred vision, cough due to consumptive disease.
Poria cocos can invigorating the spleen, and can excreting dampness, for diarrhea caused by insufficiency of the spleen dysfunction of the spleen in transportation and transformation, band under, have sample simultaneous using Poria cocos
The effect of Gu, often with the compatibility such as Radix Codonopsis, the bighead atractylodes rhizome, Chinese yam.Also tonifying lung spleen is can be used as, controls the adjuvant of the deficiency of vital energy.The traditional Chinese medical science thinks that Poria cocos can
For palpitaition, the disease such as insomnia.Poria cocos energy mental-tranquilization, therefore available for the disease such as confused and worried, palpitaition, insomnia, often with ginseng, far
The compatibilities such as will, spina date seed.
Mulberry fruit is sweet, cold in nature, have promote the production of body fluid to quench thirst, nourishing yin and supplementing blood, liver-kidney tonifying, controlling nocturnal emission with astringent drugs are antiabortive, it is black must dark hair, clever ear it is bright
Mesh, anti-aging, nourishing heart of calming the nerves, for dizziness and tinnitus, palpitation and insomnia, poliosis, injury thirst, Heat Diabetes, the deficiency of blood is just
It is secret.
Black soybean enters spleen, kidney channel, for body void yin deficiency, more drinks of quenching one's thirst, frequent urination, the deficiency of liver-yin and kidney-yin, has a dizzy spell, depending on thing
It is dim, or poliosis, tinea pedis oedema.
Fructus amomi acrid flavour is warm-natured, returns spleen, stomach, kidney channel, can dampness elimination appetizing, warming spleen and stopping diarrha, regulating the flow of vital energy antiabortive etc..
Donkey-hide gelatin is used for blood deficiency chlorosis, dizziness, palpitaition etc., for the good merchantable brand enriched blood.Empty, syndrome of blood deficiency person is seen to bleeding, particularly
Suitably.It can be additionally used in the chronic diseases marked by deficiency of vital energy and dry card, can moisten dry, control temperate-dryness and hinder lung, dry cough without phlegm.
Chinese herbal ointment formula (also known as cream taste side), is decocted with herbal mixture, filtering of removing slag, after taking juice to concentrate, with glue or honey etc.
The paste oral preparations that excipient modulation forms.Herbal paste, be called paste, run after fame with its formulation, belong to ball in the traditional Chinese medical science, dissipate, cream,
One of eight kinds of pellet, wine, dew, soup, ingot formulations.According to theory of traditional Chinese medical science, winter be throughout the year in preferably season for nourishing, and winter
Nourish, be optimal more using herbal paste.
The preparation method technique of the present invention is simple, and cost is low, and the radix polygonati officinalis rhizoma polygonati cream prepared is decocted with herbal mixture, contrast
Traditional Western medicine is free of hormone, to body without secondary toxic action；It will not be caused using glycitols and oligosaccharides etc. in blood glucose value and blood
The auxiliary material and food additives of the fluctuation of insulin level, produced in conventional processes cream grow the auxiliary materials such as applied honey, sugar heat
The shortcomings of amount is high, sugar content is high, and long term usage is also easy to produce hyperglycaemia, got fat, and xylitol that the present embodiment is used and oligomeric different wheat
Bud sugar has the characteristics that to make cream grow relatively low heat, good mouthfeel, regulation functions of intestines and stomach.
Embodiment 1
The present embodiment proposes a kind of radix polygonati officinalis rhizoma polygonati cream, and raw material includes as follows：Radix polygonati officinalis 90g, sealwort 90g, Chinese yam 140g are steamed, greatly
Jujube 140g, fruit of Chinese wolfberry 90g, Poria cocos 90g, mulberry fruit 90g, black soybean 90g, fructus amomi 40g, donkey-hide gelatin 40g, xylitol 100g are oligomeric different
Maltose 200g, potassium sorbate 0.4g, tartaric acid 0.1g.
The present embodiment also proposes a kind of preparation method of above-mentioned radix polygonati officinalis rhizoma polygonati cream, specifically includes following steps：By 40g donkey-hide gelatin
Crushed using Ultra-Micro Grinding Equipment, molten：Gelatin powder after crushing is added into yellow rice wine, and (weight of yellow rice wine is the two of donkey-hide gelatin weight
Times) immersion, heating water bath to whole dissolvings, obtain donkey-hide gelatin solution；Donkey-hide gelatin uses yellow rice wine molten, can reduce the fishy smell of donkey-hide gelatin, make
The paste finally given is in good taste；
Prepare clear cream：Following raw material is added in extractor：90g radix polygonati officinalis, 90g steam sealwort, 140g Chinese yams, 140g
Jujube, the 90g fruits of Chinese wolfberry, 90g Poria cocos, 90g mulberry fruits, 90g black soybean, 40g fructus amomis, 40g donkey-hide gelatin, it is small to add the immersion 1 of 700ml water
When, 100 DEG C are heated Dynamic Extraction 1.5 hours, with the filter-cloth filtering of 100 mesh, obtain the first filtrate, then filter residue is added into 500ml
Water, 100 DEG C are heated Dynamic Extraction 1.5 hours, with the filter-cloth filtering of 100 mesh, are obtained the second filtrate, are merged the first filtrate and second
Filtrate, under conditions of 60 DEG C, vacuum are -0.06MPa, concentrate is concentrated under reduced pressure to give, concentrate is filtered with 80 mesh while hot
Cloth is filtrated to get clear cream.
Prepare xylitol solution：Take 100g xylitols, 200g oligoisomaltoses, 210g water, 0.1g tartaric acid (tartaric acid
Quality for xylitol quality 0.1%), dissolve by heating and keep micro-boiling 1 hour, be stirred continuously uniformly, until solution is changed into
Light yellow clear is limpid, obtains xylitol solution；
Receive cream：Take 0.4g potassium sorbates to be dissolved in 15ml water, potassium sorbate solution is made, clear cream is poured into steam-heated
In caldron, micro-boiling is heated to, the xylitol solution of heat is poured slowly into clear cream, makes material cumulative volume for caldron volume
1/2 (situation that cream liquid is sprung up upwards occurs in cream refining mid-term, to prevent from overflowing, therefore can not fill it up with), by potassium sorbate solution plus
Enter and merge refining in caldron, heat while stirring and weaken the duration and degree of heating to keep micro-boiling, control temperature between 100~105 DEG C,
With anti-caking bed coke, when cream liquid is gradually dense, (donkey-hide gelatin adds the time can not be too for the good donkey-hide gelatin solution of half an hour addition molten before receipts cream
It is early, easily gelatinization, therefore select or so half an hour before cream is received to add), and accelerate stirring frequency, treat that the liquid-tight degree of cream is 1.26g/ml
When (100 DEG C) stop heating, cream liquid should instill agglomerating insoluble in cold water, obtain cream taste, radix polygonati officinalis rhizoma polygonati cream is obtained after cooling
800g。
Packaging storage：By the radix polygonati officinalis rhizoma polygonati cream after cooling be quickly sub-packed in clean dried, sterilizing packaging bag in, sealing envelope
Dress.Paste nourishing agent, which preferably seals, to be put at shady and cool dry or is stored in refrigerator.
Embodiment 2
The present embodiment proposes a kind of radix polygonati officinalis rhizoma polygonati cream, and raw material includes as follows：Radix polygonati officinalis 110g, sealwort 110g, Chinese yam 160g are steamed,
Jujube 160g, fruit of Chinese wolfberry 110g, Poria cocos 110g, mulberry fruit 110g, black soybean 110g, fructus amomi 60g, donkey-hide gelatin 60g, xylitol 140g,
Oligoisomaltose 280g, potassium sorbate 0.6g, tartaric acid 0.14g.
The present embodiment also proposes a kind of preparation method of above-mentioned radix polygonati officinalis rhizoma polygonati cream, specifically includes following steps：By 60g donkey-hide gelatin
Crushed using Ultra-Micro Grinding Equipment, molten：Gelatin powder after crushing is added into yellow rice wine, and (weight of yellow rice wine is the two of donkey-hide gelatin weight
Times) immersion, heating water bath to whole dissolvings, obtain donkey-hide gelatin solution；Donkey-hide gelatin uses yellow rice wine molten, can reduce the fishy smell of donkey-hide gelatin, make
The paste finally given is in good taste；
Prepare clear cream：Following raw material is added in extractor：110g radix polygonati officinalis, 110g steaming sealworts, 160g Chinese yams,
160g jujubes, the 110g fruits of Chinese wolfberry, 110g Poria cocos, 110g mulberry fruits, 110g black soybean, 60g fructus amomis, 60g donkey-hide gelatin, add 900ml
Water soaks 1.5 hours, 110 DEG C of heating Dynamic Extractions 2 hours, with the filter-cloth filtering of 120 mesh, obtains the first filtrate, then by filter residue
700ml water is added, 110 DEG C are heated Dynamic Extraction 2 hours, with the filter-cloth filtering of 120 mesh, obtain the second filtrate, merge the first filter
Liquid and the second filtrate, under conditions of 70 DEG C, vacuum are -0.08MPa, concentrate is concentrated under reduced pressure to give, by concentrate while hot
Clear cream is obtained with 80 mesh filter-cloth filterings.
Prepare xylitol solution：Take 140g xylitols, 280g oligoisomaltoses, 290g water, 0.14g tartaric acid (winestones
Acid quality for xylitol quality 0.1%), dissolve by heating and keep micro-boiling 3 hours, be stirred continuously uniformly, until solution become
It is limpid for light yellow clear, obtain xylitol solution；
Receive cream：Take 0.6g potassium sorbates to be dissolved in 25ml water, potassium sorbate solution is made, clear cream is poured into steam-heated
In caldron, micro-boiling is heated to, the xylitol solution of heat is poured slowly into clear cream, makes material cumulative volume for caldron volume
2/3 (situation that cream liquid is sprung up upwards occurs in cream refining mid-term, to prevent from overflowing, therefore can not fill it up with), by potassium sorbate solution plus
Enter and merge refining in caldron, heat while stirring and weaken the duration and degree of heating to keep micro-boiling, control temperature between 100~105 DEG C,
With anti-caking bed coke, when cream liquid is gradually dense, (donkey-hide gelatin adds the time can not be too for the good donkey-hide gelatin solution of half an hour addition molten before receipts cream
It is early, easily gelatinization, therefore select or so half an hour before cream is received to add), and accelerate stirring frequency, treat that the liquid-tight degree of cream is 1.27g/ml
When (100 DEG C) stop heating, cream liquid should instill agglomerating insoluble in cold water, obtain cream taste, radix polygonati officinalis rhizoma polygonati cream is obtained after cooling
980g。
Packaging storage：By the radix polygonati officinalis rhizoma polygonati cream after cooling be quickly sub-packed in clean dried, sterilizing Packaging Bottle in, capping it is close
Envelope encapsulation.Paste nourishing agent, which preferably seals, to be put at shady and cool dry or is stored in refrigerator.
Embodiment 3
The present embodiment proposes a kind of radix polygonati officinalis rhizoma polygonati cream, and raw material includes as follows：Radix polygonati officinalis 100g, sealwort 100g, Chinese yam 150g are steamed,
Jujube 150g, fruit of Chinese wolfberry 100g, Poria cocos 100g, mulberry fruit 100g, black soybean 100g, fructus amomi 50g, donkey-hide gelatin 50g, xylitol 120g,
Oligoisomaltose 240g, potassium sorbate 0.5g, tartaric acid 0.12g.
The present embodiment also proposes a kind of preparation method of above-mentioned radix polygonati officinalis rhizoma polygonati cream, specifically includes following steps：By 50g donkey-hide gelatin
Crushed using Ultra-Micro Grinding Equipment, molten：Gelatin powder after crushing is added into yellow rice wine, and (weight of yellow rice wine is the two of donkey-hide gelatin weight
Times) immersion, heating water bath to whole dissolvings, obtain donkey-hide gelatin solution；Donkey-hide gelatin uses yellow rice wine molten, can reduce the fishy smell of donkey-hide gelatin, make
The paste finally given is in good taste；
Prepare clear cream：Following raw material is added in extractor：100g radix polygonati officinalis, 100g steaming sealworts, 150g Chinese yams,
150g jujubes, the 100g fruits of Chinese wolfberry, 100g Poria cocos, 100g mulberry fruits, 100g black soybean, 50g fructus amomis, 50g donkey-hide gelatin, add 800ml
Water is soaked 1.5 hours, and 105 DEG C are heated Dynamic Extraction 1.8 hours, with the filter-cloth filtering of 100 mesh, obtains the first filtrate, then will filter
Slag adds 600ml water, 105 DEG C of heating Dynamic Extractions 1.8 hours, with the filter-cloth filtering of 100 mesh, obtains the second filtrate, merges the
One filtrate and the second filtrate, under conditions of 65 DEG C, vacuum are -0.07MPa, concentrate is concentrated under reduced pressure to give, by concentrate
While hot clear cream is obtained with 80 mesh filter-cloth filterings.
Prepare xylitol solution：Take 120g xylitols, 240g oligoisomaltoses, 250g water, 0.12g tartaric acid (winestones
Acid quality for xylitol quality 0.1%), dissolve by heating and keep micro-boiling 2 hours, be stirred continuously uniformly, until solution become
It is limpid for light yellow clear, obtain xylitol solution；
Receive cream：Take 0.5g potassium sorbates to be dissolved in 20ml water, potassium sorbate solution is made, clear cream is poured into steam-heated
In caldron, micro-boiling is heated to, the xylitol solution of heat is poured slowly into clear cream, makes material cumulative volume for caldron volume
2/3 (situation that cream liquid is sprung up upwards occurs in cream refining mid-term, to prevent from overflowing, therefore can not fill it up with), by potassium sorbate solution plus
Enter and merge refining in caldron, heat while stirring and weaken the duration and degree of heating to keep micro-boiling, control temperature between 100~105 DEG C,
With anti-caking bed coke, when cream liquid is gradually dense, (donkey-hide gelatin adds the time can not be too for the good donkey-hide gelatin solution of half an hour addition molten before receipts cream
It is early, easily gelatinization, therefore select or so half an hour before cream is received to add), and accelerate stirring frequency, treat that the liquid-tight degree of cream is 1.27g/ml
When (100 DEG C) stop heating, cream liquid should instill agglomerating insoluble in cold water, obtain cream taste, radix polygonati officinalis rhizoma polygonati cream is obtained after cooling
900g。
Packaging storage：By the radix polygonati officinalis rhizoma polygonati cream after cooling be quickly sub-packed in clean dried, sterilizing packing box in, capping it is close
Envelope encapsulation.Paste nourishing agent, which preferably seals, to be put at shady and cool dry or is stored in refrigerator.
The effect of the blood-nourishing that replenishes qi to invigorate the spleen, filling liver kidney can be reached to illustrate radix polygonati officinalis rhizoma polygonati cream of the present invention, with by above-described embodiment 1
Radix polygonati officinalis rhizoma polygonati cream is tested made from method in~3, to prove that it has the effect of replenish qi to invigorate the spleen blood-nourishing, filling liver kidney, but
It can not form any restrictions to the scope of the present invention.
Using radix polygonati officinalis rhizoma polygonati cream of the present invention treatment women Qi and blood deficiency 28, wherein 26~30 years old 7,31~40 years old 13
Example, 41~57 years old 8.The course of disease is 16 within 1 year, 1~2 year 9, more than 2 years 3.Therapeutic effect：Recover 18, improvement 9
Example, effective 1.
Typical treatment case
Field, female, 35 years old, often shortness of breath uncomfortable in chest was dizzy, limbs fatigue, indigestion, and tcm diagnosis is Qi and blood deficiency, liver
Kidney-yin deficiency.The radix polygonati officinalis rhizoma polygonati cream that the embodiment of the present invention 1 is prepared is taken, three times a day, a 15g, one after each meal, takes three
Taken a turn for the better after individual month, continue above symptom after taking three months and disappear.
To certain, female, 42 years old, soreness and weakness of waist and knees, shortness of breath uncomfortable in chest, insomnia and dreamful sleep 1 year, tcm diagnosis was Qi and blood deficiency, liver kidney
The deficiency of Yin.The radix polygonati officinalis rhizoma polygonati cream that the embodiment of the present invention 2 is prepared is taken, three times a day, a 15g, one after each meal, takes half a year
Positive effect afterwards, qi and blood is sufficient after continuing to take half a year, soreness and weakness of waist and knees, the symptom of shortness of breath uncomfortable in chest no longer occurs, sleeps.
Peng, female is 37 years old, dizzy, fatiguability, and mood is difficult to automatic control, and irritability is irritated, and tcm diagnosis is Qi and blood deficiency, liver
Kidney-yin deficiency.The radix polygonati officinalis rhizoma polygonati cream that the embodiment of the present invention 3 is prepared is taken, three times a day, a 15g, one after each meal, takes half
Mood is more gentle after year, and spirit more preferably, continues the symptom of dizziness no longer occur after taking half a year, the state of mind is good, and phychology flattens
With.
Above case shows that radix polygonati officinalis rhizoma polygonati cream provided by the invention has replenish qi to invigorate the spleen blood-nourishing, filling liver kidney and other effects, for
Deficiency of Yin anemia and cause the deficiency of liver-yin and kidney-yin, the crowd of visual impairment has significant curative effect, while radix polygonati officinalis rhizoma polygonati cream provided by the invention
Clinic does not find adverse reaction, and drug safety is reliable.
The preferred embodiments of the present invention are these are only, are not intended to limit the scope of the invention, it is every in the present invention
Design under, the equivalent transformation made using description of the invention, or directly/to be used in other related technical areas indirectly equal
It is included within the scope of the present invention.
Claims (9)
1. a kind of radix polygonati officinalis rhizoma polygonati cream, it is characterised in that the raw material of the radix polygonati officinalis rhizoma polygonati cream includes by weight：Radix polygonati officinalis 90~
110 parts, 90~110 parts of sealwort of steaming, 140~160 parts of Chinese yam, 140~160 parts of jujube, 90~110 parts of the fruit of Chinese wolfberry, Poria cocos 90~
110 parts, 90~110 parts of mulberry fruit, 90~110 parts of black soybean, 40~60 parts of fructus amomi, 40~60 parts of donkey-hide gelatin, xylitol 100~140
Part, 200~280 parts of oligoisomaltose, 0.4~0.6 part of potassium sorbate, 0.1~0.14 part of tartaric acid.
A kind of 2. preparation method of radix polygonati officinalis rhizoma polygonati cream as claimed in claim 1, it is characterised in that the original of the radix polygonati officinalis rhizoma polygonati cream
By weight, the preparation method comprises the following steps material：
Prepare donkey-hide gelatin solution：40~60 parts of donkey-hide gelatin are crushed, molten, obtain the donkey-hide gelatin solution；
Prepare clear cream：Following raw material is added in extractor：90~110 portions of radix polygonati officinalis, 90~110 parts of steaming sealworts, 140~
160 portions of Chinese yams, 140~160 portions of jujubes, 90~110 portions of fruits of Chinese wolfberry, 90~110 parts of Poria cocos, 90~110 portions of mulberry fruits, 90~110
Part black soybean, 40~60 parts of fructus amomis, the water immersion of 700~900 parts by weight is added, Dynamic Extraction is heated, filtering, obtains first
Filtrate, then filter residue is added into 500~700 parts by weight water, Dynamic Extraction is heated, filtering, obtains the second filtrate, merges the first filtrate
With the second filtrate, concentrate is concentrated under reduced pressure to give, the concentrate is filtrated to get the clear cream；
Prepare xylitol solution：Take 100~140 parts by weight xylitols, 200~280 parts by weight oligoisomaltoses, 210~300
Parts by weight water, 0.1~0.14 parts by weight tartaric acid, dissolve by heating and keep micro-boiling, are stirred continuously uniformly, obtain the xylitol
Solution；
Receive cream：Take 0.4~0.6 parts by weight potassium sorbate to be dissolved in 15~25 parts by weight water, potassium sorbate solution is made, described in
Clear cream is poured into open-top receptacle, is heated to micro-boiling, and the xylitol solution is poured into the clear cream, it is molten to add potassium sorbate
Liquid, micro-boiling is kept, be eventually adding the donkey-hide gelatin solution, agitating and heating, obtain cream taste, the radix polygonati officinalis rhizoma polygonati cream is obtained after cooling.
3. preparation method as claimed in claim 2, it is characterised in that the tool for preparing molten described in donkey-hide gelatin solution step
Body step is：Donkey-hide gelatin after crushing is added into yellow rice wine immersion, heating water bath to whole dissolvings.
4. preparation method as claimed in claim 2, it is characterised in that it is described prepare clear cream step reclaimed water immersion time be
1~1.5 hour；The heating-up temperature of the heating Dynamic Extraction is 100~110 DEG C, and the time is 1.5~2 hours.
5. preparation method as claimed in claim 2, it is characterised in that the filter cloth filtered in described the step of preparing clear cream is 80
~120 mesh；The temperature being concentrated under reduced pressure is 60~70 DEG C, and vacuum is -0.06~-0.08MPa.
6. preparation method as claimed in claim 2, it is characterised in that dissolved by heating in described the step of preparing xylitol solution
And it is 1~3h to be kept for time of micro-boiling.
7. preparation method as claimed in claim 2, it is characterised in that be heated to be steam heating in described the step of receiving cream；Will
After the xylitol solution pours into the clear cream, material cumulative volume is the 1/2~2/3 of open-top receptacle volume.
8. the preparation method as any one of claim 2~7, it is characterised in that stirring adds in described the step of receiving cream
The temperature of heat is 100~105 DEG C, when the liquid-tight degree of the cream is 1.26~1.27g/ml, stops heating.
9. the preparation method as any one of claim 2~7, it is characterised in that the preparation method also includes：By institute
Radix polygonati officinalis rhizoma polygonati cream is stated to be sub-packed in packing container, it is hermetically sealed.
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| CN108125233A (en) * | 2018-03-09 | 2018-06-08 | 山东承御堂阿胶有限公司 | A kind of kidney tonifying sealwort draft cream is grown |
| CN108721499A (en) * | 2018-06-19 | 2018-11-02 | 泸州德高生物科技有限公司 | The preparation method of polygonatum Solomon's seal binary paste nourishing agent |
| CN111528476A (en) * | 2020-06-10 | 2020-08-14 | 杭州方回春堂健康科技有限公司 | Compatible composition of ginseng and rhizoma polygonati honey tablets and preparation method |
| CN112890180A (en) * | 2021-03-04 | 2021-06-04 | 北京汉后中医研究院 | Donkey-hide gelatin, sea cucumber and polygonatum odoratum paste and preparation method thereof |
| CN112971122A (en) * | 2021-03-04 | 2021-06-18 | 北京汉后中医研究院 | Donkey-hide gelatin, agastache rugosus and sealwort extract and preparation method thereof |
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| CN115530375A (en) * | 2022-10-21 | 2022-12-30 | 青阳县禅悦食品工贸有限公司 | Polygonatum sibiricum vitality-nourishing paste, preparation method and preparation device |
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| CN108125233A (en) * | 2018-03-09 | 2018-06-08 | 山东承御堂阿胶有限公司 | A kind of kidney tonifying sealwort draft cream is grown |
| CN108721499A (en) * | 2018-06-19 | 2018-11-02 | 泸州德高生物科技有限公司 | The preparation method of polygonatum Solomon's seal binary paste nourishing agent |
| CN111528476A (en) * | 2020-06-10 | 2020-08-14 | 杭州方回春堂健康科技有限公司 | Compatible composition of ginseng and rhizoma polygonati honey tablets and preparation method |
| CN111528476B (en) * | 2020-06-10 | 2023-07-04 | 杭州方回春堂健康科技有限公司 | A composition containing Ginseng radix, rhizoma Polygonati and Mel tablet and its preparation method |
| CN112890180A (en) * | 2021-03-04 | 2021-06-04 | 北京汉后中医研究院 | Donkey-hide gelatin, sea cucumber and polygonatum odoratum paste and preparation method thereof |
| CN112971122A (en) * | 2021-03-04 | 2021-06-18 | 北京汉后中医研究院 | Donkey-hide gelatin, agastache rugosus and sealwort extract and preparation method thereof |
| CN112971123A (en) * | 2021-03-04 | 2021-06-18 | 北京汉后中医研究院 | Donkey-hide gelatin and fingered citron three-flower paste and preparation method thereof |
| CN114190556A (en) * | 2021-12-27 | 2022-03-18 | 华润圣海健康科技有限公司 | Spleen-tonifying and stomach-nourishing food and preparation method thereof |
| CN115530375A (en) * | 2022-10-21 | 2022-12-30 | 青阳县禅悦食品工贸有限公司 | Polygonatum sibiricum vitality-nourishing paste, preparation method and preparation device |
| CN116870086A (en) * | 2023-08-03 | 2023-10-13 | 北京德道堂健康科技有限公司 | Traditional Chinese medicine formula for reinforcing deficiency and strengthening tendons and bones |
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Application publication date: 20171222 |