CN107485695A - A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of lophatherum gracile - Google Patents
A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of lophatherum gracile Download PDFInfo
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- CN107485695A CN107485695A CN201710738890.XA CN201710738890A CN107485695A CN 107485695 A CN107485695 A CN 107485695A CN 201710738890 A CN201710738890 A CN 201710738890A CN 107485695 A CN107485695 A CN 107485695A
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- Prior art keywords
- lophatherum gracile
- squeezing
- vacuum drying
- fresh
- concoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/13—Preparation or pretreatment of starting material involving cleaning, e.g. washing or peeling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/31—Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
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- Medical Informatics (AREA)
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- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of lophatherum gracile.The technique is cleaned, eluted after the harvesting of lophatherum gracile medicinal material, and takes advantage of fresh squeezing, leaching concoction.The dregs of a decoction add water stirring, filtering squeezing.Gained concoction is concentrated under reduced pressure after merging, and is dried in vacuo, is vacuum-packed after crushing.Lophatherum Herb medicine materical crude slice prepared by this method, remains the polarity in medicinal material and nonpolar active ingredient to greatest extent.Medicine materical crude slice is beneficial to accumulating, and convenient to adjust, quality controllable, curative effect is reliable, to ensureing that tcm clinical curative effect has great importance.The promotion and implementation of this law, will there are significant social effect and economic benefit.
Description
Technical field
The invention belongs to Chinese medicine manufacture field, more particularly to the processing technology of Chinese medicine lophatherum gracile medicine materical crude slice.
Background technology
Chinese medicine lophatherum gracile is grass family lophatherum gracile category herbaceos perennial, there is refrigerant, antipyretic, diuresis and the effect hastened parturition.
Clinic cures mainly：In the heart disease heat, cough with dyspnea, haematemesis, heat toxin wind, only quench one's thirst, press borax poison, dissolving phlegm, control it is fanatical unhappiness, apoplexy mistake
Sound in silence, pain intermittent headache, stop palpitate with fear etc..
The processing mode of conventional lophatherum gracile medicine materical crude slice is：After harvesting, impurity is removed, is dried, directly packing storage and transport.
These dry lophatherum gracile Hygienic Indexes can not be up to standard, easily occur medicinal material go mouldy, so as to cause the decline of medical material quanlity and
The reduction of clinical efficacy.Such prepared herbal medicine in small pieces ready for decoction, it is bulky, easily occur it is rotten and contaminated, quality it is difficult to ensure that, be unfavorable for adjusting
Agent prescription and ensure its clinical efficacy.
At present, in the market also has the manufactured granule pieces sale after extraction of lophatherum gracile medicinal material.The preparation of granule pieces
Process, extraction not only time consumption and energy consumption, and do solvent because commonly using substantial amounts of water, the nonpolar active ingredient in medicinal material is difficult to be carried
Take out.Further, since the lophatherum gracile medicinal material of extraction is also to dry and by storage for a long time, therefore, active ingredient
Loss is also very big.In order to ensure lophatherum gracile medicinal material clinic effectively, steady quality, a kind of new lophatherum gracile medicine materical crude slice and its
Preparation technology urgently develops.
The content of the invention
The invention discloses " a kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of lophatherum gracile ".This technique can be most
The polarity and the nonpolar active ingredient that retain in lophatherum gracile medicinal material of limits, avoid medicinal material from being processed and accumulating in existing medicine materical crude slice
During the loss of caused active ingredient and the decline of medical material quanlity, reduce medicinal material by mould etc. pollution, to ensuring henon bamboo
The steady quality and clinical safety of leaf medicine materical crude slice effectively have great importance.
To achieve these goals, the technical scheme is that：
Its herb is gathered in lophatherum gracile picking time, is cleaned, after washing, takes advantage of fresh squeezing.In the dregs of a decoction after squeezing, 1 ~ 5 times of amount is added
Water, stir 5 ~ 30min, take juice with plate and frame filter press press filtration.The remaining dregs of a decoction press extracting juice again.Merge concoction three times, with 40 ~
120 mesh screens, obtain lophatherum gracile concoction.Obtained lophatherum gracile concoction is concentrated under reduced pressure into relative density under the conditions of 40 ~ 75 DEG C
For 1.05 ~ 1.30 medicinal extract, and it be crushed into 60 ~ 120 mesh sieves after 4 ~ 8 hours in 40 ~ 70 DEG C of vacuum drying, is vacuum-packed,
Produce fresh squeeze of lophatherum gracile and be dried in vacuo powder decoction pieces.
On the label of product packaging bags, the name of an article in printing, medicinal part, planting site, medicine materical crude slice manufacturer, the date of manufacture,
The information such as Contents of Main Components, meridian distribution of property and flavor, major function, usage and dosage, toxic side effect and contraindication.Lophatherum gracile is enclosed in bag
Thin layer differentiate collection of illustrative plates and/or efficient liquid phase characteristic spectrum, " identity card " as product.In addition, in the packaging bag of product,
Quick Response Code is printed on, can be linked by scanning and obtain the former plant photo of product, medicinal material photo, medicine materical crude slice photo, character and micro-
The information such as diagnostic characteristics.
The present invention is advantageous in that：
The lophatherum gracile medicinal material of fresh collection, clean and directly squeezed after washing, filter, be concentrated under reduced pressure, being dried in vacuo, resulting powder
Last medicine materical crude slice, the active ingredient in medicinal material can be retained to greatest extent.This medicine materical crude slice volume compared to traditional medicine materical crude slice volume significantly
Ground reduces, vacuum packaging so that prepared slice quality is more stable, is adjusted beneficial to accumulating and clinic, and there is very significant society to anticipate
Justice and economic implications.
Embodiment
Embodiment 1
By the lophatherum gracile medicinal material of fresh collection, clean, silt is washed with water, take advantage of using fresh herb squeezer pressure extracting juice.The gained dregs of a decoction add 3
The drinking water of amount again, stir 20min, plate and frame filter press pressure extracting juice.The remaining dregs of a decoction press extracting juice with squeezer again.Will be above-mentioned
3 times concoction merges, with 100 mesh sieve net filtrations.Filtrate decompression concentrates, and temperature is set as 65 DEG C.It is relatively close in medicinal extract obtained by concentration
Spend for 1.15 when, be transferred in vacuum drying chamber, in 60 DEG C dry 8 hours, low-temperature grinding, moisture be not higher than 12%.
Embodiment 2
By the lophatherum gracile medicinal material of fresh collection, clean, silt is washed with water, take advantage of using fresh herb squeezer pressure extracting juice.The gained dregs of a decoction add 5
The drinking water of amount again, stir 30min, plate and frame filter press pressure extracting juice.The remaining dregs of a decoction press extracting juice with squeezer again.Will be above-mentioned
3 times concoction merges, with 80 mesh sieve net filtrations.Filtrate decompression concentrates, and temperature is set as 70 DEG C.In medicinal extract relative density obtained by concentration
For 1.10 when, be transferred in vacuum drying chamber, in 65 DEG C dry 6 hours, low-temperature grinding, moisture be not higher than 12%.
Above example, only illustrate the technological thought of this invention, it is impossible to it is all whereby to limit protection scope of the present invention
It is any change for being done on the basis of technical scheme according to technological thought proposed by the present invention, each falls within what the present invention protected
Within the scope of.
Claims (2)
- A kind of 1. fresh preparation technology for squeezing vacuum drying powder decoction pieces of lophatherum gracile, it is characterised in that：Gathered in lophatherum gracile picking time Its herb, is cleaned, and after washing, takes advantage of fresh squeezing, the dregs of a decoction add the water of 1 ~ 5 times of amount, stir 5 ~ 30min, and plate and frame filter press press filtration takes Juice, the remaining dregs of a decoction press extracting juice again, merge concoction three times, 40 ~ 120 mesh screens, obtain lophatherum gracile concoction.
- A kind of 2. fresh preparation technology for squeezing vacuum drying powder decoction pieces of lophatherum gracile according to claim 1, it is characterised in that： By obtained lophatherum gracile concoction be concentrated under reduced pressure under the conditions of 40 ~ 75 DEG C relative density be 1.05 ~ 1.30 medicinal extract, and by its in 40 ~ 70 DEG C vacuum drying 4 ~ 8 hours after crushed 60 ~ 120 mesh sieves, be vacuum-packed, produce lophatherum gracile it is fresh squeeze vacuum drying powder Medicine materical crude slice.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710738890.XA CN107485695A (en) | 2017-08-25 | 2017-08-25 | A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of lophatherum gracile |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710738890.XA CN107485695A (en) | 2017-08-25 | 2017-08-25 | A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of lophatherum gracile |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107485695A true CN107485695A (en) | 2017-12-19 |
Family
ID=60646744
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710738890.XA Pending CN107485695A (en) | 2017-08-25 | 2017-08-25 | A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of lophatherum gracile |
Country Status (1)
| Country | Link |
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| CN (1) | CN107485695A (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105520987A (en) * | 2016-02-11 | 2016-04-27 | 徐自升 | Folium artemisiae argyi fresh juice vacuum-dried decoction powder and preparation process thereof |
| CN105596417A (en) * | 2016-02-11 | 2016-05-25 | 徐自升 | Freshly squeezed herba periliae vacuum-dried powder decoction pieces and preparation technology thereof |
| CN105998133A (en) * | 2016-07-23 | 2016-10-12 | 徐漫 | Chinese lobelia freshly-squeezed vacuum drying powder decoction tablets and preparation process thereof |
| CN106074687A (en) * | 2016-07-31 | 2016-11-09 | 徐漫 | A kind of Rabdosia rubescens is fresh squeezes vacuum drying powder decoction pieces and preparation technology thereof |
-
2017
- 2017-08-25 CN CN201710738890.XA patent/CN107485695A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105520987A (en) * | 2016-02-11 | 2016-04-27 | 徐自升 | Folium artemisiae argyi fresh juice vacuum-dried decoction powder and preparation process thereof |
| CN105596417A (en) * | 2016-02-11 | 2016-05-25 | 徐自升 | Freshly squeezed herba periliae vacuum-dried powder decoction pieces and preparation technology thereof |
| CN105998133A (en) * | 2016-07-23 | 2016-10-12 | 徐漫 | Chinese lobelia freshly-squeezed vacuum drying powder decoction tablets and preparation process thereof |
| CN106074687A (en) * | 2016-07-31 | 2016-11-09 | 徐漫 | A kind of Rabdosia rubescens is fresh squeezes vacuum drying powder decoction pieces and preparation technology thereof |
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| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20171219 |