CN107260587A - Thief zone resists camellia compound essential oil of skin aging and preparation method thereof strenuously - Google Patents
Thief zone resists camellia compound essential oil of skin aging and preparation method thereof strenuously Download PDFInfo
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- CN107260587A CN107260587A CN201710517819.9A CN201710517819A CN107260587A CN 107260587 A CN107260587 A CN 107260587A CN 201710517819 A CN201710517819 A CN 201710517819A CN 107260587 A CN107260587 A CN 107260587A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B3/00—Refining fats or fatty oils
- C11B3/001—Refining fats or fatty oils by a combination of two or more of the means hereafter
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B3/00—Refining fats or fatty oils
- C11B3/006—Refining fats or fatty oils by extraction
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B3/00—Refining fats or fatty oils
- C11B3/008—Refining fats or fatty oils by filtration, e.g. including ultra filtration, dialysis
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B3/00—Refining fats or fatty oils
- C11B3/10—Refining fats or fatty oils by adsorption
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B3/00—Refining fats or fatty oils
- C11B3/12—Refining fats or fatty oils by distillation
Abstract
A kind of Thief zone resists the camellia compound essential oil of skin aging strenuously, is uniformly mixed according to mass fraction by following component:4~20 parts of 75~95 parts of small molecule camellia oil, 0.5~3 part of Rose Absolute, 0.5~1 part of functional component and base oil component.Wherein Rose Absolute is uniformly mixed according to mass fraction by 0.1~1 part of cypress essential oil, 0.1~1 part of refined jasmine oil, 0.1~1 part of sandalwood essential oil；Wherein functional component is uniformly mixed according to mass fraction by vitamin E or 0.1~0.3 part of 0.1~0.2 part of its succinate, 0.1~0.3 part of Rosmarinus officinalis extract, Tea Polyphenols or its fatty acid ester；Wherein base oil is uniformly mixed according to mass fraction by 2~8 parts of jojoba oil, 1~5 part of rose-seed oil, 0.5~3 part of natural saualane, 0.5~2 part of Trivent OCG.The camellia compound essential oil is without greasy feeling, and osmotic absorption is good, and anti-skin aging oxidation resistance is strong, can moisten skin deeply.
Description
Technical field
The present invention relates to a kind of essential oil, particularly a kind of Thief zone resists the camellia compound essential oil of skin aging strenuously.
Background technology
In current Cosmetic Market, skin care item are the categories ranked the first, and accounting is close to 30%, and sales volume has nearly 160
Hundred million yuan.Skin care item are primarily referred to as the product maintained for individual's skin, typically have moist, whitening, moisturizing, anti-aging by function point
Deng product, essential oil class product therein, due to its pure plant characteristic, and obvious special efficacy, increasingly disappeared by vast
The concern and accreditation of the person of expense.
Essential oil class product, is generally divided into folk prescription essential oil and compound essential oil.
Folk prescription essential oil, be from a certain position with medication effect of medication plant, it is especially a certain with fragrance taste
Position, the single plant elite of extraction, generally with the botanical name or plant parts name nominating, typically has more strong
This plant scent, and with specific effect and characteristics of personality.
Compound essential oil, is, to reach specific using effect or curative effect, two or more folk prescription essential oils to be mixed, essential oil and essence
Can be mutually coordinated between oil, some also have the effect complemented each other, heightened the effect of a treatment, then add base oil to mix.
Camellia oil, also known as Wild camellia seed oil, tea-seed oil, camellia seed oil, squeeze the seed from tea oil tree.The tradition system of camellia oil
Making process includes shelling, drying, crushing, extracting oil, and filters, overall process is physical method, is fully natural green edible oil.The biography
Erucic acid, cholesterol, aflatoxins and other additives are free of in the tea oil that system technique is pressed, is beneficial to the unsaturated fat of human body
Acid content is up to more than 90%, wherein oleic acid 80-83%, linoleic acid 7-13%, and especially contained linoleic acid, leukotrienes are human bodies
Must and it can not synthesize, rich in vitamin E etc..Camellia oil contains the unrighted acid higher than olive oil and natural dimension
Raw element E, also containing the natural nourishing skin care ingredient such as Tea Polyphenols, squalene, tsubakisaponin and a variety of anti-oxidant, anti-inflammations into
Point, it is the holy product of beauty treatment moisturizing, its beauty functions particularly successive dynasties women population is praised highly, continued to use thousand.
Camellia oil, although with above-mentioned advantage, but because main component is fatty glyceride, viscosity is larger, molecule compared with
When greatly, for skin care item, often show that percutaneous absorption is slow, assimilation effect is poor, skin greasy feeling substantially, the shortcomings of be easily sticky with.
The content of the invention
The purpose of the present invention, is to overcome the deficiencies in the prior art to be answered there is provided the camellia that a kind of Thief zone resists skin aging strenuously
Square essential oil.
The technical scheme is that：
A kind of Thief zone resists the camellia compound essential oil of skin aging strenuously, is uniformly mixed according to mass fraction by following component:
4~20 parts of 75~95 parts of small molecule camellia oil, 0.5~3 part of Rose Absolute, 0.5~1 part of functional component and base oil component.
Described Rose Absolute is according to mass fraction by 0.1~1 part of cypress essential oil, 0.1~1 part of refined jasmine oil, santal essence
0.1~1 part of oil is uniformly mixed.
Described functional component is extracted according to mass fraction by vitamin E or 0.1~0.2 part of its succinate, rosemary
0.1~0.3 part of 0.1~0.3 part of thing, Tea Polyphenols or its fatty acid ester are uniformly mixed.
Described base oil is according to mass fraction by 2~8 parts of jojoba oil, 1~5 part of rose-seed oil, natural saualane 0.5
~3 parts, 0.5~2 part of Trivent OCG is uniformly mixed.
Described small molecule camellia oil, is go glycerine reaction of the camellia oil with ethanol under highly basic existence condition, then through dividing
From, purification, obtained small molecule camellia oil remains the oleic acid for being beneficial to human body in camellia oil, linoleic acid, leukotrienes, also protects
The vitamin E for being beneficial to human body in camellia oil, Tea Polyphenols, sterol, squalene, tsubakisaponin etc. has been stayed naturally to nourish skin care ingredient
And a variety of anti-oxidant, anti-inflammation compositions.
Preferably, small molecule camellia oil is anti-by 75~85 parts of camellia oil, 15~25 parts of food-grade ethanol, highly basic 0.2~1.0
It should form.
Preferably, it can be made up of following processing step：
Step 1: producing small molecule camellia oil crude product
Raw material is weighed by following proportion by weight：75~85 parts of camellia oil, 15~25 parts of food-grade ethanol, highly basic 0.2~1.0
Part；By the camellia oil weighed, 40~60 DEG C are heated to；Load weighted highly basic is added in food-grade ethanol, makes it fully molten
Solution, is made into alcohol aqueous slkali；Alcohol aqueous slkali is slowly added in camellia oil, 40~70 DEG C, constant temperature stirring at low speed 30~60 are heated to
Minute；It is heated to 80~100 DEG C, constant temperature high-speed stirred 1~2 hour；Cooling, stands 3~4 hours, takes edible vegetable oil liquid thereon；Will be upper
Edible vegetable oil liquid is cooled to -5~5 DEG C, stands 3~4 hours, rapid vacuum suction filtration obtains filtrate；In filtrate add proper amount of active carbon and
Atlapulgite, is heated to 80~100 DEG C, constant temperature is stirred 1-3 hours, filters to obtain high penetration small molecule camellia oil crude product；
Step 2: producing cosmetics-stage high penetration small molecule camellia oil
Step one is made into small molecule camellia oil crude product to be separated in short-range molecular distillation device, plate temperature 130~150 is scraped
DEG C, scraper velocity 200-250r/min, 0.04~0.06MPa of vacuum, condensate liquid are collected as small molecule camellia oil, and heavy phase is given up
Liquid is separately collected.
Contained fatty-acid ethyl ester molecule in the small molecule camellia oil is smaller very than contained fatty glyceride in camellia oil
It is many, where this is the reason for its penetration original is higher than camellia oil, in addition, small molecule camellia oil remain camellia oil it is contained beneficial to
Most contents of the unrighted acids such as oleic acid, linoleic acid, the leukotrienes of human body, remain camellia oil contained vitamin E,
The major part that Tea Polyphenols, squalene, Tea Saponin etc. are naturally nourished in skin care ingredient and a variety of anti-oxidant, anti-inflammation compositions contains
Amount, thus, not only percutaneous absorption speed is fast, and maintenance effect is good, and skin does not have greasy feeling substantially, is not easy to be sticky with, and solves mountain
Percutaneous absorption effect that tea oil has is poor, skin greasy feeling is strong, the shortcomings of be easily sticky with.It is harmful on being typically considered to
Alcohol problems, after tested, detection ethanol in end in the small molecule camellia oil, and ethanol Permissible limit is in cosmetics
2000mg/Kg（《Cosmetics health specification》Version in 2007）.
Preferably, in the step one, camellia oil does not add using obtained by camellia seed physical squeezing by further
Work, it is to avoid the unreasonable refining losses of the contained mentioned component beneficial to human body.
Preferably, in the step one, this kind of camellia oil sorting is good, and processing technology is rationally, contained above-mentioned to be beneficial to human body
Composition content it is high.
In the step one, highly basic can be the one or more in sodium hydroxide, potassium hydroxide, caustic alcohol, potassium ethoxide,
It is preferred that sodium hydroxide cheap and easy to get.
Preferably, in the step one, camellia oil conversion ratio is more than 90%.
Preferably, in the step 2, the distillation yield 60~65% of high penetration small molecule camellia oil is controlled, now, is steamed
Distillation unit operating is more steady, and the quality of gained small molecule camellia oil is preferable.
Preferably, the distillation heavy phase waste liquid in the step 2 is reclaimed, and replaces camellia oil raw material, by being similar to step
One method prepares small molecule camellia oil crude product again, then is separated by the method for step 2, and condensate liquid is used as small molecule mountain
Tea oil is collected, and what distillation heavy phase waste liquid was abandoned no longer uses.
Preferably, Rosmarinus officinalis extract is fat-soluble Rosmarinus officinalis extract, the liposoluble in the compound essential oil functional component
Property Rosmarinus officinalis extract in the functional component, resist skin aging camellia compound essential oil strenuously in Thief zone of the present invention in dissolubility
More preferably, disperse more preferable, more stable, be more beneficial for playing its effect.
Thief zone of the present invention resists the preparation method of skin aging camellia compound essential oil strenuously, each component is uniformly mixed and
Into.
Thief zone of the present invention resists the use of skin aging camellia compound essential oil strenuously, generally with semar technique, such as appropriate to smear
In skin, then press lightly on, moderately rub until fully absorbing.
Camellia compound essential oil of the present invention, its preparation technology is simple and reliable, and small molecule camellia oil is remained in camellia oil
It is beneficial to the oleic acid, linoleic acid, leukotrienes of human body, is compounded with other raw materials, can effectively cooperate with each active factors to penetrate into skin, promotees
Enter skin metabolism, and product naturally nourishes skin care ingredient rich in vitamin E, Tea Polyphenols, squalene, Tea Saponin etc. and a variety of anti-
Oxidation, anti-inflammation composition, percutaneous absorption speed is fast, effect is good, and skin does not have greasy feeling substantially, is not easy to be sticky with, solves
Percutaneous absorption effect that camellia oil has is poor, skin greasy feeling is strong, the shortcomings of be easily sticky with.
The camellia compound essential oil, stability is good, non-toxic, nonirritant, without anaphylaxis, superpower osmotic absorption, promotes
Cell mobilization, repairs elastomer, increases skin elasticity.
Primary raw material used in the present invention is described as follows：
Camellia oil：Camellia seed kernel is through cleaning, air-drying（Temperature is less than 100 DEG C）, shelling, seed selection sterilization after, at 20-50 DEG C carry out
Squeezing gained, active material enriches, generally about containing vitamin E 200mg/Kg, sterol 30mg/Kg, squalene 100mg/
Kg。
Jojoba oil：Also known as jojoba seed oil, SIMMONDSIA CHINENSIS SEED OIL（SIMMONDSIA CHINENSIS, No. CAS:61789-91-
1, INCI：SIMMONDSIA CHINENSIS (JOJOBA) SEED OIL）, it is the monounsaturated fatty acids and straight chain of straight chain
Monounsaturated fatty acid alcohol composition fat.Jojoba, is to be grown in South West USA and Mexico northwest one with Arid desert region
A kind of wild plant, the king of Ren Cheng worlds oil plant.Jojoba oil, is to refine and obtain after flash crotons are squeezed through cold pressing, in gold
Yellow, cured containing abundant mineral matter, vitamin, protein, collagen, plant, moisturizing effect is good, tasteless, and oil is relatively light to be slided seemingly
The grease of adipose gland secretion, permeability is good, extremely stablizes, resistance to strong light, high temperature resistant, and holding structure is constant, can hide long.He Heba
The chemical molecular structure of oil is very similar with the sebum of the mankind, is easy to by skin and absorption, is adapted to all skin quality, especially
It is adapted to dry, coarse, dark and gloomy, oiliness, whelk skin quality, there are very significant beauty functions to skin, it is important natural containing skin
Vitamin and collagenic protein, mineral matter containing high nourishing degree, can massage and protect skin, it is to avoid water loss, nourish deep layer
Skin is takeed good care of, makes skin gloss flexible, and relaxes the injury to skin of exposing to the weather；Skin pH balances can be recovered, wrinkle is gone
Line, is effectively improved Oily, nurses one's health smegma function, pore refining, while being also optimal skin moisture-keeping oil.It institute
The oil film of formation is different from mineral oil, can pass through the moisture of evaporation, can also control the loss of moisture, and improves the skin of inflammation,
Eczema, chronic eczema, pimples etc., it has suitable curative effect to allergic skin with releiving, will not produce acne and antigen, is various skins
The base oil that skin property can be used；Absorption and maintenance that hair moistens material to external world can be promoted, and can be impaired to scalp
Keratan cell rise maintenance effect, its gloss that rejuvenates can be made to Dry Hair and dryness wrinkle skin.Substantial amounts of safety
Property and toxicological test confirm, Jojoba Oil be used as cosmetics be foolproof.
Rose-seed oil：English name Rose hip seed Oil, Classification system Rosamosqueta, CAS:84603-93-0,
Chinese name rose hip oil.It is derived from a kind of Fruits of Wild Rosa Rugosa Thunb of South America.Main component includes γ-linolenic acid, unsaturated lipid
Fat acid, palmitic acid, citric acid, vitamin A, C, carotenoid.Suitable for any skin quality, it is particularly suitable for water shortage, maturation, aging
Skin, the skin for spot and sunburn occur, are a kind of vegetable oil particularly advantageous to women.Effect includes：1st, work(is repaired
Energy：Eliminate scar and pit, to caused by acne, operation, burn, varicella, wound and otch skin injury scar it is all effective,
Dissolve blackhead, pore refining, eliminate red and swollen erythema, the strong cytothesis of rose hip oil and wound healing function help to be good for
The growth of health, normal skin, substitutes scar tissue；2nd, Firm smoothing wrinkle function：Skin aging is prevented, can be by promoting epidermal cell
Activity improve skin regeneration and updating ability, so as to stop and reverse the classical symptom such as wrinkle, eye of skin aging generation
Angle wrinkle and relaxation, with the disappearance of aging phenomenon, skin of face will become consolidation and smooth；3rd, whitening function：Mitigate color
Plain calm, it can promote the ability of skin hyperplasia neoblast, and as new cell replaces the cell of aging, pigmentation spot is just
Can gradually it mitigate.Rose hip oil can also mitigate due to pigment caused by gestation, repair sun-damaged skin, desalinate blackspot freckle, recover
Tender fine flour hole；4th, nourishing and moisturizing function：Again the skin that moisturizing is dried, when grease secreted by four or five ten years old skin is more than 20 year old
10 times are reduced, the reduction and the disappearance of moisture-keeping functions secreted due to skin oil and fat may result in the production of drying and dehydrating and wrinkle
It is raw.Rose hip oil can recover the optimum balance between aliphatic acid and moisture, the skin that moisturizing is dried again.
Saualane：English name SQUALANE, CAS:111-01-3, also known as eepwater shark liver oil, are from hydrogenated hydro carbons grease
The squalene of middle extraction is hydrogenated to be made a kind of squalene extracting of excellent performance, colourless, tasteless, nontoxic, chemical inertness, light and
It is transparent；Assign product fabulous and noble feel, feel very abundant after, moisten and non-greasy；The moistness of height and moisturizing
Property；Inoxidizability and excellent heat stability；There is crease-resistant effect, available in anti-wrinkle product；Skin is not stimulated, not sensitization, it is non-
Chang Anquan, it is strongly recommended that in child care products.The hydrocarbons that saualane is made up of six isoprene double bonds, belong to
Polyisoprenoid structure.Do not only exist in shark liver, and be also the internal substance in human body.Courage is participated in vivo because the biology of alcohol is closed
Into and a variety of biochemical reactions, promote the metabolism of biological oxidation and body, improve the defensive enginery of body, stress ability and body
Heart quality, accelerates class because of alcohol hormone sensitive lipase gene, the activity of activated adenyl cyclase causes the Level of Camp of second messenger to increase
Plus.Internal hepatocuprein and lactic acid dehydrogenase activity can be significantly improved, anti-oxidant and anti-skin aging energy is significantly improved
Power.Affinity is strong, can be combined together with the sebum film of mankind itself, in skin surface one layer of natural barrier of formation；Can also
Suppress the peroxidating of skin lipid, can effectively infiltrate through skin, and promote the propagation of skin base cell, it is old to delaying skin
Change, improving and eliminating chloasma has obvious physiologic effect；Can also skin pore be opened, promote blood microcirculation, promoted
Damaged cell is repaired in the metabolism of cell, help.
Trivent OCG：INCI title CAPRYLIC TRIGLYCERIDE, common name：GREOIL GTCC, CAS:
65381-09-1.The derivative of colourless or light yellow clear oily liquids, category palm oil or coconut oil.It is widely used in food
The industries such as product, medicine, cosmetics, and be proved to human body without any excitant.It is easy to be absorbed by the skin, to the equal of cosmetics
It is even and fine it is greasy play good effect, make skin lubrication glossy.Can as moisturizing factor base-material, the stabilizer of cosmetics, prevent
Freeze agent, homogeneous agent.
Cypress essential oil：Also known as Mediterranean pitch, CNIC：Cypress（Cupressus sempervirens）Oil, CAS:
8013-86-3.This product is that cypressCypressus cupressaceae plant cypress tree Fresh leaves and cone distillation are formed.It is colourless or in extremely light yellow,
There is amber taste charming as wooden and face cream.Main component is note alkene（65%, especially beta pinene and terpinol）, cedrol, snow
Loose camphor, number acid and tannin.Greasy, aged skin can be nursed one's health, can be restrained and skin of releiving, fat secretion is adjusted, tightened
Pore, keeps isohydria, controls water loss, quite helpful to adult form skin, also has regulation to hidrosis and oily skin
Effect.Energy dispelling fatigue, angry mood of releiving, alleviate heart anxiety and pressure, purify one's soul simultaneously.
Refined jasmine oil：Also known as jasmine caul-fat, INCI JASMINE（JASMINUM OFFICINALE) OIL, CAS:8022-
96-6.Main component includes benzyl acetate, linalool, benzyl alcohol, indoles, benzyl benzoin ester, jasmone, spiceleaf
Alcohol, methyl（It is adjacent）Aminobenzoate, micro cresols, farnesol, vinyl benzoin ester, eugenol, nerol, rest in peace
Fragrant acid, benzaldehyde, terpineol, neroli oil, phytol etc..It can nurse one's health and dry and sensitive skin, desalination striae of pregnancy and scar,
Increase skin elasticity, delay skin aging effect is notable.
Sandalwood essential oil：Also known as sandalwood oil, INCI SANDALWOOD (SANTALUMALBUM) OIL, CAS:8006-87-9.
With the effect for promoting dermal cell growth, wound or scar can be restored rapidly, and then flexible, deflation effect；It is flat
Weighing apparatus and softening skin, improvement are dried, desalination texture, are particularly suitable for aging, dried the maintenance of water shortage skin and neck.Antibacterial work(
Effect, improvement skin is itched, inflammation, improves pimples, furuncle and infected wound.A few drop sandalwood essential oils are instilled in the hot water of bubble pin, can
To reach the purpose of promoting blood circulation channels and collaterals, moreover it is possible to reach the effect for removing tinea pedis foot odour.
Rosmarinus officinalis extract:INCI ROSEMARY (ROSMARINUS OFFICINALIS) EXTRACT, CAS:
84604-14-8.Rosemary, Labiatae Rosmarinus, shrub is high up to 2 meters.Active ingredient includes carnosic acid, Salvia japonica
Phenol, rosmanol, ursolic acid, Rosmarinic acid, major function is anti-oxidant, can improve activities of antioxidant enzymes in human body, suppresses
Lipid peroxidation, the effect with anti-aging, contained Rosmarinic acid and carnosic acid and skin epidermis compatibility are good, are difficult
Be flush with water loss, so good absorbing effect, antioxidation is strong, can also effective stimulus scalp blood circulation, sterilizing and itch-relieving, extensively
It is general to be used for hair products.
Tea Polyphenols：Also known as tea tannin, tannin, English name Tea Polyphenols, CAS:84650-60-2.With extremely strong
Harmful free radicals Scavenging activity, block lipid peroxidation process, improve the activity of human enzymes, thus play anti-mutation, it is anti-
Effect of cancer；Important role is metabolized to body fat, it is possible to decrease the content of cholesterol, triglycerides etc., removes blood vessel
Inwall fat deposition and atheromatous plaque；LOX and lipid peroxidation in skin mitochondria can be suppressed, so that
With anti-aging effect.Antioxidant is substantially better than vitamin E, and has synergy with injection Vitamin B_6；It is water-soluble substances, energy
The greasy of face is removed, pore is restrained, with sterilization, sterilizing, resisting age of skin, the ultraviolet radiation in daylight is reduced to skin
Damage the effects such as, can stop ultraviolet and remove ultraviolet induction free radical, so as to protect the normal of melanocyte
Function, suppresses the formation of melanin, suppresses lipid oxidation, mitigates pigmentation.
Embodiment
Embodiment 1
The high penetration small molecule camellia oil of embodiment 1, is made up of following processing step：
Step 1: producing high penetration small molecule camellia oil crude product
Camellia oil 7500g, food-grade ethanol 2000g, sodium hydroxide 20g are weighed by mass fraction；Camellia oil is heated to 60 DEG C；
Sodium hydroxide is added in food-grade ethanol, it is fully dissolved, is made into alcohol aqueous slkali；Alcohol aqueous slkali is slowly added to camellia oil
In, it is heated to 70 DEG C, constant temperature stirring at low speed 0.5 hour；It is heated to 80 DEG C, constant temperature high-speed stirred 2 hours；It is quickly cooled to often
Temperature, stands 4 hours, takes edible vegetable oil liquid thereon；Supernatant fluid is cooled fast to -5 DEG C（The temperature stood after the cooling of supernatant fluid）,
Stand 3 hours（The time stood after the cooling of supernatant fluid）, fast vacuum suction filtration obtains filtrate 7434ml（Amount of filtrate）；In filtrate
Middle addition 100g activated carbons（Activated carbon addition in filtrate）With 300g atlapulgites（Atlapulgite addition in filtrate）, heating
To 100 DEG C（Filtrate extraction temperature）, constant temperature stirring 1 hour（Filtrate Refining times）, filter to obtain high penetration small molecule camellia oil
Crude product 6528ml；
Step 2: producing cosmetics-stage high penetration small molecule camellia oil
Step one is made into high penetration small molecule camellia oil crude product to be separated in short-range molecular distillation device, plate temperature is scraped
130 DEG C, scraper velocity 200r/min, vacuum 0.06MPa, condensate liquid are collected as small molecule camellia oil, obtain 4047ml, heavy phase
Waste collection, obtains 2481ml.
Embodiment 2-6
Embodiment 2-6 high penetration small molecule camellia oil, the basic be the same as Example 1 of its preparation process condition, simply reaction raw materials
And the condition such as proportion scale, temperature, time is slightly different, specifically as listed in table 1.
Embodiment 7
Gained heavy phase waste liquid will be separated and collected in embodiment 1-6 medium or short range molecular distillation apparatus, it is every kind of respectively to take 1300g, altogether
7800g, substitution camellia oil adds food-grade ethanol 1000g, other basic be the same as Examples of step of preparation process as reaction raw materials
1, simply the condition such as proportion scale, temperature, time be slightly different, specifically as listed in table 1.
The embodiment 1-7 of table 1 high penetration small molecule camellia oil preparation process condition
Embodiment 8-14
Respectively with embodiment 1-7 high penetration small molecule camellia oil, other raw materials are equipped with, through uniform mixing, reality is obtained successively
The Thief zone for applying a 8-14 resists the camellia compound essential oil of skin aging strenuously, and specific dispensing situation is as listed in table 2.
Comparative example 1
With the raw materials used camellia oil of embodiment 4, replace the high penetration small molecule camellia oil in embodiment 11, other dispensings and ratio
Example be the same as Example 1, is well mixed, obtained Thief zone resists the compound camellia oil of skin aging strenuously, as a comparison case, is specifically listed in table
2。
Comparative example 2
Comparative example 2 eliminates sandalwood essential oil on the basis of embodiment 11, and other are identical with embodiment 11.
Comparative example 3
Comparative example 3 eliminates natural saualane on the basis of embodiment 11, and other are identical with embodiment 11.
The embodiment 8-14 of table 2 and comparative example dispensing situation, unit for gram
Embodiment 8-14 Thief zones resist the camellia compound essential oil of skin aging and the performance feelings of comparative example 1-3 compound camellia oils strenuously
Condition, including viscosity, osmotic absorption speed, performance of keeping humidity, DPPH free radical scavenging activities, antioxidative stabilizer, are specifically listed in table 3.
The embodiment 8-14 of table 3 and comparative example behavior pattern
Used method of testing is as follows in table 3:
(1) Thief zone resists the camellia compound essential oil of skin aging and the viscosity of compound camellia oil strenuously, is determined using capillary tube method；
(2) osmotic absorption speed and performance of keeping humidity one are the impressions after human hand back use；
(3) method of testing of performance of keeping humidity two：
Drying is a key character of ageing skin, and skin can be alleviated significantly experimental results demonstrate the moisture in skin is kept
Aging problem.Therefore the barrier function of skin is repaired, the moisture pinned in skin just turns into an important anti-aging approach.
A sets up experimental model
The skin for simulating people with pigskin allows moisture evaporation in its natural state, regularly claims its quality, calculates protect according to the following formula
Wet rate, evaluates its moistening effect.
Moisturizing rate R=（Hn/Ho）× 100%, Hn is the quality of sample after n hour in formula, and Ho is the initial quality of sample.
B experimental procedures
Thief zone obtained by Example 8-11 resists the camellia compound essential oil of skin aging strenuously, and totally 4 samples, as experimental group, take
As a control group, 6 are handled altogether for 1% glycerine, 1% hyaluronic acid.A smooth pigskin is taken, removes unnecessary grease and cleans dry
Only, pigskin is cut into 3cm × 3cm test sample, 10min is soaked in distilled water, allows pigskin to fully absorb moisture, after taking-up
Stand 24h standby.Camellia compound essential oil, 1% glycerine, each 20ml of 1% hyaluronic acid are taken respectively, are placed in 50ml small beaker.Will
The pigskin prepared is put into the beaker of above-mentioned different disposal respectively, is taken out pigskin after immersion 30min, is drained away the water, claim respectively
Take to be placed on after quality in 20 DEG C of temperature, the environment of relative humidity 78% and allow moisture natural evaporation；Preceding 12h claims 1 inferior quality every 2h,
12h claims 1 inferior quality, record data and the moisturizing rate for calculating each item for disposal every 4h afterwards.
C result statistics and analysis
Table 4 lists the simulation performance of keeping humidity situation that embodiment 8-11 Thief zones resist the camellia compound essential oil of skin aging strenuously, with
1% glycerine, 1% hyaluronic acid are as control, and moisturizing rate unit is %.
The simulation performance of keeping humidity situation of the embodiment 8-11 camellia compound essential oils of table 4（%）
Test result indicates that：The camellia compound essential oil said according to the present invention has excellent performance of keeping humidity, or even significantly exceeds
Conventional NMF（Glycerine, hyaluronic acid）Performance of keeping humidity, for moisturizing and nourishing skin, anti-skin aging keeps skin water
Dividing has important effect.
(4) DPPH free radical scavenging activities method of testing:
According to the free radical theory of aging, excessive free radical can cause body injury to cause aging.Free radical is vital movement
During biochemical reaction intermediate product.Under normal circumstances, the generation and removing of machine interior free yl are flat in dynamic
Among weighing apparatus, if but it produce in vivo it is excessive or removed it is slow, will be in molecular level, cellular level and organ level to machine
Body causes damage, and can accelerate the aging course of body.Therefore removing excessive free radical turns into the important means of resistance aging.
The Biological Free Radicals relevant with life aging are mainly some oxygen containing free radicals, such as active oxygen radical
(O2 -), Both peroxyl radical (HO2), hydroxyl radical free radical (OH) etc..Antioxidant can provide proton to peroxidating
Thing free radical, it is thus possible to suppress the autoxidizable chain reaction of lipid.(DPPH+AH (antioxidant) → DPPH
+ HA) examine antioxidant to put forward protogenic ability usually using DPPH (C18H12N6O5).DPP
H is a kind of very stable free radical, and its ethanol solution has an extremely strong absorbance at 517nm, but when being oxidized agent (AH)
Or during free radical (R) reduction, its absorbance can be reduced or disappeared.Thus, it can be sentenced using absorbance of the product at 517nm
Whether fixed output quota product have the ability for removing free radical, so as to judge whether with anti-aging oxidation resistant effect.
DPPH is the stabilized radical containing odd electron, and the principle of this method is can in 517nm using its ethanol solution
Seeing has extremely strong absorbance under light, but when it is combined or reduced by antioxidant with any free radical, its absorbance can under
Drop；Absorbance is lower, represents that sample removing DPPH ability is stronger, specific method of testing is as follows:
Take 0.2ml testing samples, 3.8ml ethanol, 1ml (2 × 10-4Mol/L) DPPH free radicals ethanol solution, is mixed, and is stood
After 30min, with absorbance at spectrophotometric measurement 517nm, and its free radical scavenging activity, free radical scavenging activity are calculated with formula
(%)=[(Ac-As)/Ac] × 100%, wherein, absorbance when As is containing testing sample, when Ac is without testing sample
Absorbance, absorbance is lower, represent sample remove DPPH ability it is stronger.
(5) antioxidative stabilizer method of testing：
Test objective：When oxidation of the camellia compound essential oil of Observe and measure embodiments of the invention under different high-temperature conditions is induced
Between calculate that oxidation stability is fixed and shelf life, be that the Thief zone of embodiments of the invention resists the camellia compound essential oil of skin aging strenuously
Product stability foundation is provided.
Test apparatus：Oil oxidative stability analyzer（743 types are led in Switzerland ten thousand）
Experimental procedure：Randomly select the 8-11 embodiments of the present invention camellia compound essential oil weigh respectively it is appropriate in 100,110,
120th, oxidation induction time is determined at 130 DEG C, export shelf life by system plug-in is also carried out to comparative example 1-3 simultaneously
Determine.
Result of the test is shown in Table 5.
Table 5
Conclusion (of pressure testing)：The camellia compound essential oil that the Thief zone of various embodiments of the present invention resists skin aging strenuously has significant oxidation
Stability.
Result listed by table 3,4,5 illustrates that Thief zone of the present invention resists the camellia compound essential oil of skin aging strenuously, and viscosity is low, oozes
Saturating power is strong, easily absorbs, and DPPH free radical scavenging activities are high, and antioxidative stabilizer is good, and performance is better than compound camellia oil, with excellent
Performance of keeping humidity, in addition containing multiple beneficial composition as described above, can play holding skin moisture, moisturizing and nourishing skin, anti-flesh
Skin aging etc. acts on and reaches preferable maintenance effect.
In addition, the Thief zone obtained by embodiment 8-14 to be resisted to the camellia compound essential oil of skin aging strenuously, by examining micro- life
Thing index, sanitary index《Cosmetics health specification》（Version in 2007）, obtain the testing result shown in table 6 below：
Table 6
Thief zone of the present invention resists the camellia compound essential oil toxicology test of skin aging strenuously：Skin irritation test（Multiple skin
Irritation test）.
Test objective：Observe rabbit intact skin long-time multiple-contact tested material（The camellia of embodiments of the invention is answered
Square essential oil）Produced skin irritation reaction afterwards, is that the Thief zone of embodiments of the invention is resisted the camellia of skin aging strenuously and answered
Square essential oil provides security foundation.
Test basis：《Cosmetics health specification》Version in 2007.
Test method：From white New Zealand rabbits 8,2 groups, every group 4 are randomly divided into.A groups:Intact skin group, B groups:
Olive sunflower oil control group.24h cuts family's rabbit back backbone both sides hair before experiment, not injured skin surface in cropping, goes
Hair scope is 3cm × 3cm, and application area is 2.5cm × 2.5cm., high penetration of the tested material group to various embodiments of the present invention
The camellia compound essential oil of anti-skin aging, takes tested material 0.5ml to be coated directly on the side of back backbone, and opposite side applies 0.5ml pairs
According to a group olive sunflower oil, smear 1 time daily, continuously smear 14d.Since second day, olive sunflower was used in cropping when smearing every time
Oil removes residual tested material.Result is observed after one hour, according to《Cosmetics health specification》The skin irritation of version in 2007
Table scoring is tested, check plot and trial zone are equally handled.
Evaluation of result：Every rabbit average integral daily is calculated according to the following formula, is pierced by specification list deciding rabbit skin
Swash intensity, and observe other toxic actions in addition to excitant.
Result of the test：Tested material was carried out in the multiple skin irritation test observation period, gave the height of various embodiments of the present invention
Infiltration is resisted strenuously after the camellia compound essential oil of skin aging, and rabbit has no erythema, oedema.Have no systemic toxicity profiles performance and dead feelings
Condition, the weight of animals increase, on breathing, circulation, central nervous system, four limbs activity etc. without influence.
Conclusion (of pressure testing)：The Thief zone of various embodiments of the present invention resists the camellia compound essential oil of skin aging strenuously to white new west
Blue rabbit intact skin is nonirritant.
Claims (10)
1. a kind of Thief zone resists the camellia compound essential oil of skin aging strenuously, it is made up according to mass fraction of following component:Thief zone
4~20 parts of 75~95 parts of power small molecule camellia oil, 0.5~3 part of Rose Absolute, 0.5~1 part of functional component and base oil component.
2. Thief zone resists the camellia compound essential oil of skin aging strenuously according to claim 1, it is characterised in that：The described fragrance of a flower
Essential oil is according to mass fraction by 0.1~1 part of cypress essential oil, 0.1~1 part of refined jasmine oil, the uniform mixing of 0.1~1 part of sandalwood essential oil
Form.
3. Thief zone resists the camellia compound essential oil of skin aging strenuously according to claim 1, it is characterised in that：Described function
Composition is according to mass fraction by vitamin E or 0.1~0.2 part of its succinate, 0.1~0.3 part of Rosmarinus officinalis extract, Tea Polyphenols
Or 0.1~0.3 part of its fatty acid ester is uniformly mixed.
4. resist the camellia compound essential oil of skin aging strenuously according to any Thief zones of claim 1-3, it is characterised in that：It is described
Base oil according to mass fraction by 2~8 parts of jojoba oil, 1~5 part of rose-seed oil, 0.5~3 part of natural saualane, octanoic acid it is sweet
Oily 0.5~2 part of three ester is uniformly mixed.
5. Thief zone resists the camellia compound essential oil of skin aging strenuously according to claim 1, it is characterised in that：Described height
Penetration small molecule camellia oil, is made via following processing step：
Step 1: producing high penetration small molecule camellia oil crude product
Raw material is weighed by following proportion by weight：75~85 parts of camellia oil, 15~25 parts of food-grade ethanol, highly basic 0.2~1.0
Part；By the camellia oil weighed, 50~60 DEG C are heated to；Load weighted highly basic is added in food-grade ethanol, makes it fully molten
Solution, is made into alcohol aqueous slkali；Alcohol aqueous slkali is slowly added in camellia oil, 60~70 DEG C, constant temperature stirring at low speed 30~60 are heated to
Minute；It is then heated to 80~100 DEG C, constant temperature high-speed stirred 1~2 hour；Cooling, stands 3~4 hours, takes edible vegetable oil liquid thereon；
Supernatant fluid is cooled to -5~5 DEG C, 3~4 hours are stood, rapid vacuum suction filtration obtains filtrate；Appropriate activity is added in filtrate
Charcoal and atlapulgite, are heated to 80~100 DEG C, constant temperature is stirred 1-3 hours, filters to obtain high penetration small molecule camellia oil crude product；
Step 2: producing cosmetics-stage high penetration small molecule camellia oil
Step one is made into high penetration small molecule camellia oil crude product to be separated in short-range molecular distillation device, plate temperature is scraped
130~150 DEG C, scraper velocity 200-250r/min, 0.04~0.06MPa of vacuum, condensate liquid is used as high penetration small molecule
Camellia oil is collected, and heavy phase waste liquid is separately collected.
6. Thief zone resists the camellia compound essential oil of skin aging strenuously according to claim 5, it is characterised in that：The step one
In, camellia oil is using crude oil obtained by physical squeezing.
7. Thief zone resists the camellia compound essential oil of skin aging strenuously according to claim 5, it is characterised in that：The step one
In, highly basic is the one or more in sodium hydroxide, potassium hydroxide, caustic alcohol, potassium ethoxide.
8. Thief zone resists the camellia compound essential oil of skin aging strenuously according to claim 5, it is characterised in that：The step 2
In heavy phase waste liquid reclaimed, replace camellia oil raw material, prepare small point of high penetration again by the method for being similar to step one
Sub- camellia oil crude product, then separated by the method for step 2, condensate liquid is high penetration small molecule camellia oil, and distillation heavy phase is given up
Liquid abandons it.
9. Thief zone resists the camellia compound essential oil of skin aging strenuously according to claim 3, it is characterised in that：The rosemary
Extract is fat-soluble Rosmarinus officinalis extract.
10. Thief zone resists the preparation method of skin aging camellia compound essential oil strenuously according to claim 1, it is characterised in that will
Each component is uniformly mixed.
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| CN110484353A (en) * | 2019-08-23 | 2019-11-22 | 福建师范大学 | A kind of preparation method of water solubility camellia oil |
| CN111184653A (en) * | 2019-12-17 | 2020-05-22 | 杭州千岛湖天鑫有限公司 | Vegetable oil skin care composition and preparation method thereof |
| CN114288213A (en) * | 2021-12-27 | 2022-04-08 | 伊犁紫苏丽人生物科技有限公司 | Novel natural composite tea oil foot soaking gel bead and preparation method thereof |
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| CN104434643A (en) * | 2014-11-14 | 2015-03-25 | 浙江久晟茶业发展有限公司 | Camellia soothing oil and preparation method thereof |
| CN104983607A (en) * | 2015-07-14 | 2015-10-21 | 华南理工大学 | Massage essential oil, preparation method thereof and application thereof |
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| CN101717691A (en) * | 2009-10-30 | 2010-06-02 | 华南理工大学 | Method for refining cosmetic camellia oil by adopting short-path distillation |
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| CN110484353A (en) * | 2019-08-23 | 2019-11-22 | 福建师范大学 | A kind of preparation method of water solubility camellia oil |
| CN111184653A (en) * | 2019-12-17 | 2020-05-22 | 杭州千岛湖天鑫有限公司 | Vegetable oil skin care composition and preparation method thereof |
| CN114288213A (en) * | 2021-12-27 | 2022-04-08 | 伊犁紫苏丽人生物科技有限公司 | Novel natural composite tea oil foot soaking gel bead and preparation method thereof |
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