CN104983607A - Massage essential oil, preparation method thereof and application thereof - Google Patents
Massage essential oil, preparation method thereof and application thereof Download PDFInfo
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Abstract
The invention discloses massage essential oil, a preparation method thereof and application thereof. The massage essential oil consists of the following components in percentage by mass: 10 to 20 percent of plum tree oil, 10 to 20 percent of camellia oil, 2 to 5 percent of grapefruit oil, 2 to 5 percent of orange essential oil, 2 to 5 percent of sweet almond essential oil, 2 to 5 percent of chamomile essential oil, 2 to 5 percent of hackmatack essential oil, 0.1 to 0.5 percent of hyaluronic acid, and the balance of basic oil. The components are uniformly mixed to form the massage essential oil. The massage essential oil is clean and bright in color and luster, transparent and safe, is not irritating, has the effects of removing free radicals and improving skin pruritus, and can be used for preparing skin nursing products to improve skin.
Description
Technical field
The invention belongs to daily-use chemical industry technical field, particularly one massage quintessence oil and preparation method thereof and application.
Background technology
Quintessence oil is made up of some micromolecule, has volatility, enters health, then information is delivered directly to brain by nose breathing road, thus regulates emotion and improve the effects such as skin.Compound essential Oil forms according to the allotment of various plants quintessence oil heterogeneity, uses more convenient, just as preparing the patent medicine of prescription by compound essential Oil according to the modulation of certain ratio.In the compound process of quintessence oil, not only to consider the assimilation effect of quintessence oil, also will consider the compatibility between the smell coordination of quintessence oil and quintessence oil.
The rhythm of life of modern is than very fast, and pressure is comparatively large, some unsound life style in addition, as a long time facing to computer, often to stay up late etc. and makes skin occur the problems such as coarse, fuel-displaced, acne, long pox, xerosis cutis.Not yet there is the essential oil product that can effectively address these problems at present, the present invention massages quintessence oil based on borneol tree oil and Camellia oil, be intended to develop one can improve pachylosis, go out wet goods problem, and can be good at improving the problems such as xerosis cutis, make skin high resilience.
Summary of the invention
Primary and foremost purpose of the present invention is to overcome the deficiencies in the prior art part and defect, provides a kind of function to massage quintessence oil.
Another object of the present invention is to preparation method and range of application that above-mentioned massage quintessence oil is provided.
Object of the present invention is achieved through the following technical solutions: a kind of massage quintessence oil, is grouped into by following one-tenth by mass percentage: borneol sets oily 10-20%, Camellia oil 10-20%, grapefruit essential oil 2-5%, Citrus essential oil 2-5%, Semen pruni armeniacae quintessence oil 2-5%, chamomile essential oil 2-5%, Juniperus rigida Sieb.et Zucc. quintessence oil 2-5%, hyaluronic acid 0.1-0.5%, base oil surplus.
Described massage quintessence oil, is preferably grouped into by following one-tenth by mass percentage: borneol sets oily 10-20%, Camellia oil 10-20%, grapefruit essential oil 2-5%, Citrus essential oil 3.5-5%, Semen pruni armeniacae quintessence oil 2-5%, chamomile essential oil 2-5%, Juniperus rigida Sieb.et Zucc. quintessence oil 2-5%, hyaluronic acid 0.1-0.5%, base oil surplus.Described massage quintessence oil, is more preferably grouped into by following one-tenth by mass percentage: borneol tree oil 20%, Camellia oil 15%, grapefruit essential oil 5%, Citrus essential oil 3.5%, Semen pruni armeniacae oil 2.0%, chamomile essential oil 5.0%, Juniperus rigida Sieb.et Zucc. quintessence oil 2.0%, hyaluronic acid 0.4%, base oil surplus.
The preparation method of described massage quintessence oil, comprises the steps: the mixing of borneol tree oil, Camellia oil, grapefruit essential oil, Citrus essential oil, Semen pruni armeniacae oil, chamomile essential oil and Juniperus rigida Sieb.et Zucc. quintessence oil; Then add hyaluronic acid and base oil, mixing, obtain massaging quintessence oil;
Wherein, the content of each composition is by mass percentage, as follows: borneol sets oily 10-20%, Camellia oil 10-20%, grapefruit essential oil 2-5%, Citrus essential oil 2-5%, Semen pruni armeniacae oil 2-5%, chamomile essential oil 2-5%, Juniperus rigida Sieb.et Zucc. quintessence oil 2-5%, hyaluronic acid 0.1-0.5%, base oil surplus; Be preferably borneol and set oily 10-20%, Camellia oil 10-20%, grapefruit essential oil 2-5%, Citrus essential oil 3.5-5%, Semen pruni armeniacae quintessence oil 2-5%, chamomile essential oil 2-5%, Juniperus rigida Sieb.et Zucc. quintessence oil 2-5%, hyaluronic acid 0.1-0.5%, base oil surplus; Be more preferably borneol tree oil 20%, Camellia oil 15%, grapefruit essential oil 5%, Citrus essential oil 3.5%, Semen pruni armeniacae oil 2.0%, chamomile essential oil 5.0%, Juniperus rigida Sieb.et Zucc. quintessence oil 2.0%, hyaluronic acid 0.4%, base oil surplus.
The mode of described mixing is ultrasound wave mixing.
The condition of described ultrasonic wave concussion is preferably: 1.7MHZ shakes 15min.
Described massage quintessence oil can be used for preparing skin nursing products; Be applied to skin nursing, preferably include following steps: massage quintessence oil is coated skin surface, massages.
Described skin is preferably facial skin.
The time of described massage is preferably 10 minutes.
In formula of the present invention, the various plants essential oils of employing are the plant essences extracted from pure natural plant, are rich in multiple nutritional components with trace element, applied widely.Wherein borneol tree oil is also known as " natural d-borneol ", " natural Broneolum Syntheticum ", and be the crystallization that Dipterocarpaceae aiphyllium borneo camphor tree resin obtains through distillation cooling, its main component is natural d-borneol.Borneol tree oil not only has reducing swelling and alleviating pain, refreshment of having one's ideas straightened out, walks quickly and keeps away the effects such as mosquito, and borneol tree oil is also as a kind of effective penetration enhancer and transdermal enhancer, and Synergistic promotes other smart pick up the oil, thus improves the availability of composite essential oil; Be rich in the unsaturated fatty acids such as 90% oleic acid and linoleic acid in Camellia oil, there is antioxidation and immunity moderation function, also have in addition and improve blood circulation, reduce the effect such as blood fat, hepatoprotective; Grapefruit essential oil can nurse tissue cell, increase muscle power, to releive bronchitis, infection effect, can also resist melancholy, the melancholy especially occurred in winter or the symptom such as drowsy, people can be made to refresh, be the regulator of seasonal psychataxia, be applicable to very much oiliness and acne skin use, the sebum secretion of skin can be adjusted; Citrus essential oil abnormal smells from the patient is gentle, on the one hand can calm nerves, flatly comfort dejected and anxiety, striae gravidarum and cicatrix can be desalinated on the other hand; Semen pruni armeniacae oil abnormal smells from the patient delicate fragrance, skin-friendly is comparatively strong, very easily infiltrates through skin, containing abundant vitamin and fatty acid, effectively can improve xerosis cutis, skin care; The effects such as chamomile essential oil not only has pain relieving, antiallergic, anti-melancholy, anti-inflammatory, antipruritic, antibacterial, also can promote to scab, control wound, improve the symptom such as eczema, chronic eczema, make skin high resilience; Effect in Juniperus rigida Sieb.et Zucc. quintessence oil treatment of arthritis is held in high repute, and the people being applicable to fat-reducing uses, and helps to discharge the toxin piled up in body, is usually used in treatment acne, scytitis, convergence pore, regulates fat secretion, make skin gentle moist; Hyaluronic acid can form the ventilative thin film of one deck at skin surface, makes skin smooth moistening, thus intercepts alien bacteria, dust, ultraviolet intrusion, promote skin-nourishing Absorption, there is stronger wrinkle-chasing function, can skin elasticity be increased, effect of delay skin aging.The carrier oil Jojoba oil selected is the base oil that permeability is the strongest, is very easily absorbed by the skin, and clearly moistens non-greasy, effectively can improve oily skin, the secretory function of conditioning sebaceous gland, and pore refining, nourishes skin; Its skin-friendly is fine, is the excellent carrier of quintessence oil being brought into skin, allows skin better absorb the nutritional labeling of formula, have non-oxidizability free from worldly cares simultaneously, and other quintessence oils collaborative play effect of composite essential oil better.
The present invention has following advantage and effect relative to prior art:
(1) hyaluronic acid that the present invention uses adopts macromole hyaluronic acid, Middle molecule hyaluronic acid, micromolecule hyaluronic acid used in combination with 1:1:1, thus overcomes the skin protection restriction of single transparent matter acid, thus plays its optimal efficacy.
(2) the present invention uses borneol to set the oily effect not only with anti-inflammation, simultaneously or good transdermal enhancer, skin epidermal cells cell membrane is impelled to reset, the collaborative skin that strengthens to the absorption of Camellia oil, grapefruit essential oil, Citrus essential oil, chamomile essential oil, Semen pruni armeniacae oil, Juniperus rigida Sieb.et Zucc. quintessence oil etc., thus improves the availability of each quintessence oil; Massage quintessence oil has significant effect improving in xerosis cutis, skin pruritus etc.
(3) in experimental design procedure of the present invention, the hyaluronic acid of use can not only promote to massage the stable of quintessence oil, and avoiding the volatilization of quintessence oil, and have stronger moisture-retaining capacity, is desirable moisturizing product.
Accompanying drawing explanation
Fig. 1 is the testing result figure of hyaluronic acid to composite essential oil stability influence.
Fig. 2 is the comparative result figure of massage quintessence oil and VE antioxygenic property.
Fig. 3 is the safety evaluatio flow chart of massage quintessence oil.
Detailed description of the invention
Below in conjunction with embodiment and accompanying drawing, the present invention is described in further detail, but embodiments of the present invention are not limited thereto.
Method described in following experiment is conventional method if no special instructions; Described raw material and biological preparation are all obtained by commercial sources without specified otherwise.
Embodiment 1
The preparation of borneol tree oil: take appropriate borneol leaves (about 400g) and put into extraction pot and carry out vapor distillation, by the thick oil that obtains after-5 DEG C of lyophilization crystallizations, put into centrifuge and abandon supernatant in the centrifugal 10min of 1500rpm, obtain the borneol tree oil that purity is about mass percent 65%.
In order to determine optimum process condition of the present invention and proportioning raw materials, inventors performed a large amount of experimentatioies, concrete research contents is as follows:
Get that borneol sets oily 10-20mL, Camellia oil 10-20mL, grapefruit essential oil 2-5mL, Citrus essential oil 2-5mL, Semen pruni armeniacae oil 2-5mL, chamomile essential oil 2-5mL, Juniperus rigida Sieb.et Zucc. quintessence oil 2-5mL composite essential oil put into glass container successively, abundant mixing (1.7MHZ shakes 15min), add hyaluronic acid 0.1-0.5mL again, finally add basic quintessence oil to 100mL.After abundant mixing, its biological activity of sealing detection, thus determine its addition.
One, the modulation of quintessence oil is massaged
1, composite essential oil modulation
Quintessence oil selected by the present invention is respectively and gets borneol tree oil (A) 10-20mL, Camellia oil (B) 10-20mL, grapefruit essential oil (C) 2-5mL, Citrus essential oil (D) 2-5mL, Semen pruni armeniacae oil (E) 2-5mL, chamomile essential oil (F) 2-5mL, Juniperus rigida Sieb.et Zucc. quintessence oil (G) 2-5mL composite essential oil put into glass container, ultrasonic mix homogeneously.Borneol tree oil can promote above-mentioned smart pick up the oil, thus plays effect of each quintessence oil better.This experiment is by carrying out subjective appreciation to composite essential oil thus obtaining the optimum formula of composite essential oil.Its method mainly gets appropriate massage quintessence oil on skin, with finger tip by essential oil dispersion, moves in a circle lightly, fully absorb, then evaluate its effect to quintessence oil with two Lap Time degree per second.Massage quintessence oil sensory evaluation is respectively from outward appearance, abnormal smells from the patient, dispersibility, absorbability, judge by aspects such as rear sensations, and each judgment criteria is divided into Three Estate (as shown in table 1) respectively.L
18(3
7) Orthogonal Experiment and Design mixed preparing basis quintessence oil, often group test repetition 3 times, then by 10 testers the basic quintessence oil sensory test prepared given a mark and average (total score 100 points) range analysis and experimental result in table 2.
Quintessence oil sensory evaluation index massaged by table 1
Table 2 composite essential oil preparation orthogonal test sensory test result
In the process of carrying out orthogonal test, often organize composite essential oil as shown in Table 2 there is good organoleptic properties.By more known, in 8th group of experiment, the antioxygenic property of composite essential oil is obviously better than other each group, and namely borneol sets oily 20mL, Camellia oil 15mL, grapefruit essential oil 5.0mL, Citrus essential oil 3.5mL, Semen pruni armeniacae oil 2.0mL, chamomile essential oil 5.0mL, Juniperus rigida Sieb.et Zucc. quintessence oil 2.0mL.Optimum according to the antioxygenic property of the composite essential oil of this proportions.
2, hyaluronic acid addition
Hyaluronic acid is excellent wetting agent and nutritional labeling penetrating agent, and it can form a kind of hydration shell at skin surface, the horny layer hydration of skin can be made to soften, thus make skin tender smooth, careful bright and new.And hyaluronic acid can affect the stability of massage quintessence oil, this experiment determines hyaluronic optimum addition by the stability measuring massage quintessence oil.
(1) experimental principle: quintessence oil has volatility and unstability because of it, affects its outward appearance and result of use in the process stored.Quintessence oil instability there will be the situations such as its proportion increases, viscosity increases, darken.Therefore this experiment is by adding not commensurability hyaluronic acid, after keeping in Dark Place 7 days, will massage quintessence oil centrifugal treating, and the height of lower clear liquid is less shows that the stability of massaging quintessence oil is better, determines hyaluronic addition with this.
(2) experimental technique: get borneol and set oily 20mL, Camellia oil 15mL, grapefruit essential oil 5.0mL, Citrus essential oil 3.5mL, Semen pruni armeniacae oil 2.0mL, chamomile essential oil 5.0mL and Juniperus rigida Sieb.et Zucc. quintessence oil 2.0mL and fully mix (1.7MHZ shakes 15min), add 0.1mL ~ 0.5mL hyaluronic acid more fully to mix, add base oil (Jojoba oil) again and be diluted to 100mL, mixed liquor is loaded in centrifuge tube, with the height of clear liquid lower in the centrifugal 10min test tube of 3000r/min on centrifuge.Stability (%)=100 × (former mixed liquor height-lower Clear liquid height)/mixed liquor height of mixed liquor.Experimental result as shown in Figure 1.
As shown in Figure 1 when hyaluronic acid addition is 0.4mL, massage quintessence oil stability is best, reaches more than 90%, therefore determines that hyaluronic addition is 0.4mL.
Two, the evaluation of quintessence oil is massaged
1, antioxygen effect alive of quintessence oil is massaged
In above-mentioned massage quintessence oil, borneol is set oily 20mL, Camellia oil 15mL, grapefruit essential oil 5.0mL, Citrus essential oil 3.5mL, Semen pruni armeniacae oil 2.0mL, chamomile essential oil 5.0mL and Juniperus rigida Sieb.et Zucc. quintessence oil 2.0mL and is fully mixed (1.7MHZ shakes 15min), add after hyaluronic acid 0.4mL fully mixes again, add base oil (Jojoba oil) dilution again, the product appearance clarification obtained is weak yellow liquid.The fragrance of this massage quintessence oil is gentle, lasting fragrance, has good absorbent properties.
The detecting step of its antioxygenic property is as follows:
(1) preparation of ABTS radical reaction solution: prepare 5mM ABTS storing solution, with excessive manganese dioxide (MnO with the PBS (PBS used is with identical) of pH 7.4,10mmol/L below herein
2) be the PVDF filtering with microporous membrane of 0.2 μm through aperture after reaction, then to be diluted to 734nm place light absorption value with PBS be 0.70 ± 0.02, obtains ABTS working solution, keep in Dark Place.
(2) preparation of composite essential oil storing solution: accurately measure above-mentioned massage quintessence oil 10 μ L, dilute with DMSO and be settled to 10mL, being made into composite essential oil storing solution, being kept in-20 DEG C of refrigerators.
Experimental procedure: accurately draw above-mentioned composite essential oil storing solution 20 μ L respectively, add the ABTS working solution 180 μ L prepared in advance, fully mix, room temperature lucifuge is reacted, and at 734nm place, microplate reader surveys its absorbance.Every 5min surveys and once surveys its situation of change in 30min, investigates different time to the Scavenging activity of ABTS.The DMSO solution adding equivalent does blank.Often kind of quintessence oil preparation is analyzed sample and is repeated 3 times, asks its meansigma methods.Using VE as positive control: be settled to 10mL after being dissolved by 1.0g vitamin E DMSO, the same with above-mentioned sample step, measure it and remove ABTS free radical antioxidant activity.Formula is as follows:
Suppression ratio (%)=(A
o-A
t) X 100/A
o
In formula, A
ofor adding the absorbance of the ABTS free radical of blank DMSO, A
tfor the absorbance after sample and ABTS radical reaction.
As seen from Figure 2, example reaction system solution removes the prolongation of ability with the response time of ABTS free radical, the Scavenging activity of massage quintessence oil to ABTS strengthens successively, during reaction 30min, it is more than 90% to free radical suppression ratio, higher than the scavenging action of vitamin E to ABTS, illustrate that massage quintessence oil has very strong Scavenging ability, and presentative time dependency relationships.
2, the safety evaluatio of quintessence oil is massaged
According to the regulation of " safety evaluation of cosmetics progresses and methods GB7919 1 ", the present invention has carried out the detection of the following aspects: A, acute oral toxicity test successively; B, acute dermal toxicity are tested; C, Skin Irritation Test; D, eye irritant test.The safety evaluatio flow chart of massage quintessence oil as shown in Figure 3.
Get test mice 20 (SPF level Balb/c mice, purchased from Zhongshan University's Experimental Animal Center, 8-10 week age, 18 ~ 22g) male and female half and half, carry out acute oral toxicity test, acute dermal toxicity test, Skin Irritation Test, eye irritant test (concrete test procedure is shown in GB 7919-1987) respectively.
1. acute oral toxicity test result shows: mice in two weeks without obvious poisoning symptom, every treated animal mouse diet is normal, hair luster, activity freely, limb coordination, skin, eyes and open-minded film are without exception, breathe, circulation, the certainly central nervous system that advocates peace be without exception, without animal dead in 7 days.
2. acute dermal toxicity test finds that fur is glossy, well-grown without died in test mice 7 days, to smear after massaging quintessence oil skin without redness, this product to animal skin without overt toxicity.
3. animal subject smear massage quintessence oil place there is not erythema, edema phenomenon; Skin irritation intensity is nonirritant.
4. animal subject eye gives massage quintessence oil, 2 droplets/day, 1 droplet/time, adhere to 15 days, observing test mice eye has without exception, and result shows: this massage quintessence oil does not have zest to injure to mice eye, there is not redness, the symptom such as fuzzy in test mice eye, therefore secondary cosmetics can relievedly use.
3, quintessence oil treatment skin pruritus effective evaluation is massaged
In above-mentioned massage quintessence oil, borneol is set oily 20mL, Camellia oil 15mL, grapefruit essential oil 5.0mL, Citrus essential oil 3.5mL, Semen pruni armeniacae oil 2.0mL, chamomile essential oil 5.0mL and Juniperus rigida Sieb.et Zucc. quintessence oil 2.0mL and is fully mixed (1.7MHZ shakes 15min), add after hyaluronic acid 0.4mL fully mixes again, add base oil (Jojoba oil) again and be diluted to 100mL, the massage quintessence oil obtained.
Arrange the contrast massage quintessence oil of contrast in addition, composition is with the difference of above-mentioned massage quintessence oil: use 20mL base oil to replace 20mL borneol to set oil, and namely contrast massage quintessence oil is not containing borneol tree oil.
Massage quintessence oil and contrast massage quintessence oil are spread upon patient skin drying place, and adhere to use 30 days, observe the impact on skin, concrete scheme is as follows:
(1) study subject: the age at 18 ~ 65 years old, average 56.2 ± 15.1 years old.Man 25 example, female 25 example; Study subject is that skin exists serious dry or dry patient with sympotoms.
(2) research method: all patients are divided into treatment group 25 example, matched group 25 example.Treatment group uses massage quintessence oil, and matched group adopts contrast massage quintessence oil.Often organize patient clean water xerosis cutis place with warm alkalescence soap and proper temperature under nurse instructs, wipe dry after be evenly coated with massage quintessence oil, massage 5min gently after smearing, every day 1 time.Massage quintessence oil massages the outward appearances such as smart oil packaging, color and luster with contrast completely similar, and tests through the skin protection of ordinary people before use, does not find untoward reaction.Require that patient is at experimental session, does not use other skin care item, evaluates after 30 days.
(3) evaluation index (as table 3 and table 4).
The therapeutic effect of (4) two groups compares (see table 5): known by table 5, and compared to matched group, the therapeutic effect for the treatment of group to xerosis cutis and skin pruritus is more remarkable, and two groups to massage quintessence oil reaction all without exception, can relievedly use.Compared to matched group, treatment group adds the oily treatment that can promote xerosis cutis and skin pruritus of borneol tree, and therefore Synergistic effect of borneol tree oil plays vital effect in this massage quintessence oil.
Table 3 xerosis cutis objective indicator is evaluated
Table 4 xerosis cutis subjective index is evaluated
Compare after table 5 treatment group and treatment of control group
Effect example
One, massage quintessence oil is prepared as follows
(1) borneol is set oily 20mL, grapefruit essential oil 5.0mL, Citrus essential oil 3.5mL, Semen pruni armeniacae oil 2.0mL, chamomile essential oil 5.0mL and Juniperus rigida Sieb.et Zucc. quintessence oil 2.0mL fully to mix (1.7MHZ shakes 15min), add after hyaluronic acid 0.4mL fully mixes again, add base oil (Jojoba oil) dilution again, obtain massage quintessence oil I.
(2) borneol is set oily 20mL, Camellia oil 15mL, Citrus essential oil 3.5mL, Semen pruni armeniacae oil 2.0mL, chamomile essential oil 5.0mL and Juniperus rigida Sieb.et Zucc. quintessence oil 2.0mL fully to mix (1.7MHZ shakes 15min), add after hyaluronic acid 0.4mL fully mixes again, add base oil (Jojoba oil) dilution again, obtain massage quintessence oil II.
(3) borneol is set oily 20mL, Camellia oil 15mL, grapefruit essential oil 5.0mL, Citrus essential oil 3.5mL, chamomile essential oil 5.0mL and Juniperus rigida Sieb.et Zucc. quintessence oil 2.0mL fully to mix (1.7MHZ shakes 15min), add after hyaluronic acid 0.4mL fully mixes again, add base oil (Jojoba oil) dilution again, obtain massage quintessence oil III.
(4) borneol is set oily 20mL, Camellia oil 15mL, grapefruit essential oil 5.0mL, Citrus essential oil 3.5mL, Semen pruni armeniacae oil 2.0mL and Juniperus rigida Sieb.et Zucc. quintessence oil 2.0mL fully to mix (1.7MHZ shakes 15min), add after hyaluronic acid 0.4mL fully mixes again, add base oil (Jojoba oil) dilution again, obtain massage quintessence oil IV.
(5) grapefruit essential oil 5.0mL, Citrus essential oil 3.5mL, Semen pruni armeniacae oil 2.0mL, chamomile essential oil 5.0mL and Juniperus rigida Sieb.et Zucc. quintessence oil 2.0mL are fully mixed (1.7MHZ shakes 15min), add after hyaluronic acid 0.4mL fully mixes again, add base oil (Jojoba oil) dilution again, obtain massaging quintessence oil V.
(6) Camellia oil 15mL, Citrus essential oil 3.5mL, Semen pruni armeniacae oil 2.0mL, chamomile essential oil 5.0mL and Juniperus rigida Sieb.et Zucc. quintessence oil 2.0mL are fully mixed (1.7MHZ shakes 15min), add after hyaluronic acid 0.4mL fully mixes again, add base oil (Jojoba oil) dilution again, obtain massaging quintessence oil VI.
(7) Camellia oil 15mL, grapefruit essential oil 5.0mL, Citrus essential oil 3.5mL, chamomile essential oil 5.0mL and Juniperus rigida Sieb.et Zucc. quintessence oil 2.0mL are fully mixed (1.7MHZ shakes 15min), add after hyaluronic acid 0.4mL fully mixes again, add base oil (Jojoba oil) dilution again, obtain massaging quintessence oil VII.
(8) Camellia oil 15mL, grapefruit essential oil 5.0mL, Citrus essential oil 3.5mL, Semen pruni armeniacae oil 2.0mL and Juniperus rigida Sieb.et Zucc. quintessence oil 2.0mL are fully mixed (1.7MHZ shakes 15min), add after hyaluronic acid 0.4mL fully mixes again, add base oil (Jojoba oil) dilution again, obtain massaging quintessence oil VIII.
(9) borneol is set oily 20mL, Camellia oil 15mL, grapefruit essential oil 5.0mL, Citrus essential oil 3.5mL, Semen pruni armeniacae oil 2.0mL, chamomile essential oil 5.0mL and Juniperus rigida Sieb.et Zucc. quintessence oil 2.0mL fully to mix (1.7MHZ shakes 15min), add after hyaluronic acid 0.4mL fully mixes again, add base oil (Jojoba oil) dilution again, obtain massaging quintessence oil Ⅸ.
Two, detect
Xerosis cutis is divided into moist 0 point, slight dry 1 point (limitation pachylosis), dry 3 points (general pachylosis accompanies desquamation widely) of severe.Skin pruritus adopts behavior scoring method (BRS) namely: without pruritus 0 point, few pruritus but never state 1 point, pruritus causes slight irritated 2 points once in a while, frequent pruritus, more seriously, but does not affect movable and has a rest 3 points, frequent convulsion is itched, impact is had a rest but is not affected movable 4 points, continues pruritus, affects rest activity 5 points.
As above index is adopted to analyze above-mentioned massage quintessence oil, each massage quintessence oil test group is made up of patient 25 example and normal 25 examples, often organize patient clean water xerosis cutis place with warm alkalescence soap and proper temperature under nurse instructs, wipe after doing and be evenly coated with above-mentioned massage quintessence oil, 5min is massaged gently, every day 1 time after smearing.Require that patient is at experimental session, do not use other skin care item, evaluate after 30 days, get its meansigma methods, result is as shown in table 6.
As shown in Table 6, the effect of the present invention (massage quintessence oil IX) is best.From the interpretation of result of massage quintessence oil I ~ VIII, the therapeutic effect of massage quintessence oil I ~ IV to xerosis cutis and skin pruritus having added borneol tree oil all sets oily massage quintessence oil V ~ VIII significantly better than not adding borneol, mainly because borneol tree oil has the effect promoting Transdermal absorption, thus improve the availability of each quintessence oil; In addition, Camellia oil, grapefruit essential oil, chamomile essential oil, Semen pruni armeniacae quintessence oil are all improved the effect of xerosis cutis and pruritus, and the effect of Semen pruni armeniacae quintessence oil is stronger.Visible, the synergistic function that Camellia oil, grapefruit essential oil, chamomile essential oil, Semen pruni armeniacae quintessence oil and borneol set oil makes it more remarkable to the therapeutic effect of xerosis cutis and skin pruritus.
Table 6 massages quintessence oil to xerosis cutis and pruritus effectiveness comparison
Above-described embodiment is the present invention's preferably embodiment; but embodiments of the present invention are not restricted to the described embodiments; change, the modification done under other any does not deviate from spirit of the present invention and principle, substitute, combine, simplify; all should be the substitute mode of equivalence, be included within protection scope of the present invention.
Claims (9)
1. massage a quintessence oil, it is characterized in that being grouped into by following one-tenth by mass percentage: borneol sets oily 10-20%, Camellia oil 10-20%, grapefruit essential oil 2-5%, Citrus essential oil 2-5%, Semen pruni armeniacae quintessence oil 2-5%, chamomile essential oil 2-5%, Juniperus rigida Sieb.et Zucc. quintessence oil 2-5%, hyaluronic acid 0.1-0.5%, base oil surplus.
2. massage quintessence oil according to claim 1, is characterized in that being grouped into by following one-tenth by mass percentage: borneol sets oily 10-20%, Camellia oil 10-20%, grapefruit essential oil 2-5%, Citrus essential oil 3.5-5%, Semen pruni armeniacae quintessence oil 2-5%, chamomile essential oil 2-5%, Juniperus rigida Sieb.et Zucc. quintessence oil 2-5%, hyaluronic acid 0.1-0.5%, base oil surplus.
3. massage quintessence oil according to claim 2, is characterized in that being grouped into by following one-tenth by mass percentage: borneol tree oil 20%, Camellia oil 15%, grapefruit essential oil 5%, Citrus essential oil 3.5%, Semen pruni armeniacae oil 2.0%, chamomile essential oil 5.0%, Juniperus rigida Sieb.et Zucc. quintessence oil 2.0%, hyaluronic acid 0.4%, base oil surplus.
4. the preparation method of the massage quintessence oil described in any one of claims 1 to 3, is characterized in that comprising the steps: the mixing of borneol tree oil, Camellia oil, grapefruit essential oil, Citrus essential oil, Semen pruni armeniacae oil, chamomile essential oil and Juniperus rigida Sieb.et Zucc. quintessence oil; Then add hyaluronic acid and base oil, mixing, obtain massaging quintessence oil.
5. the preparation method of massage quintessence oil according to claim 4, is characterized in that: the mode of described mixing is ultrasound wave mixing.
6. the preparation method of massage quintessence oil according to claim 5, is characterized in that: the condition of described ultrasonic wave concussion is: 1.7MHZ shakes 15min.
7. the massage quintessence oil described in any one of claims 1 to 3 is preparing the application in skin nursing products.
8. the massage quintessence oil application in the treatment of skin described in any one of claims 1 to 3, is characterized in that comprising the steps: massage quintessence oil to coat skin surface, massages.
9. massage quintessence oil according to claim 8 application in the treatment of skin, is characterized in that: the time of described massage is 10 minutes.
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| CN106256340A (en) * | 2016-07-02 | 2016-12-28 | 国家林业局泡桐研究开发中心 | A kind of Prunus armeniaca L.var.ansu Maxim. Cortex Eucommiae massage oil and preparation method thereof |
| CN107260608A (en) * | 2017-06-29 | 2017-10-20 | 湖南大三湘油茶生态产业有限公司 | Slimming camellia massage oil of high penetration and preparation method thereof |
| CN107260587A (en) * | 2017-06-29 | 2017-10-20 | 湖南大三湘油茶生态产业有限公司 | Thief zone resists camellia compound essential oil of skin aging and preparation method thereof strenuously |
| CN107308047A (en) * | 2017-06-29 | 2017-11-03 | 湖南大三湘油茶生态产业有限公司 | Camellia compound essential oil of striae of pregnancy and preparation method thereof is repaired in prevention |
| CN109288977A (en) * | 2018-07-20 | 2019-02-01 | 王芳 | A kind of herbal treatment oil and preparation method thereof |
| CN109223627A (en) * | 2018-11-26 | 2019-01-18 | 张庆 | A kind of grapefruit essential oil massage cream |
| CN109431869A (en) * | 2018-12-22 | 2019-03-08 | 南京益唯森生物科技有限公司 | A kind of cynomorium songaricum massage essential oil and preparation method thereof |
| CN114404349A (en) * | 2021-12-16 | 2022-04-29 | 卡替睿舒(上海)医疗科技有限公司 | Calf blood and centella asiatica derived exosome composition and application thereof in skin repair |
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| CN104983607B (en) | 2018-02-27 |
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