KR101363029B1 - The cosmetic composition for anti-oxident and anti-aging of the skin comprising the Gelidium amansii, Undaria pinnatifida, wheat bud and Monarda horsemint - Google Patents

Abstract

The present invention relates to an antioxidant and anti-aging cosmetic composition containing aspen extract, wakame extract, wheat germ extract and bergamot extract as an active ingredient, the cosmetic composition according to the present invention has a radical scavenging ability compared to the case of using each component alone This excellent, excellent wrinkle improvement effect, can be usefully used as a cosmetic composition for anti-aging and wrinkle improvement.

Description

The cosmetic composition for anti-oxident and anti-aging of the skin comprising the Gelidium amansii, Undaria pinnatifida, wheat bud and Monarda horsemint}

The present invention relates to an antioxidant composition, and more particularly, to a cosmetic composition for preventing aging comprising an extract of barley, wakame, wheat germ and bergamot having a antioxidant effect and an anti-aging effect and a mixed extract thereof.

Human skin is changed by a number of internal and external factors as it ages. That is, internally, the secretion of various hormones that regulate metabolism decreases, and the function of immune cells and the activity of cells decreases, thereby reducing the biosynthesis of immune proteins and constituent proteins necessary for living organisms. Due to the increase in the amount of ultraviolet rays reaching the surface of the sun's rays and further increase environmental pollution, free radicals and free radicals, such as free radicals, skin thickness, wrinkles, elasticity is reduced only In addition, the color of the skin becomes dull, skin problems frequently occur, and blemishes, freckles, and mushrooms are also increasing.

As aging progresses, symptoms such as changes and decreases in the content and arrangement of collagen, elastin, hyaluronic acid, and glycoproteins constituting the skin appear, and are subjected to oxidative stress caused by free radicals and active harmful oxygen. As skin ages or the skin is exposed to ultraviolet light, cyclooxygenase-2 (Cox-2), an enzyme that produces proinflammatory cytokine, known to cause inflammation in most of the cells that make up skin, , the biosynthesis of cyclooxygenase increases, the biosynthesis of matrix metalloproteinase (MMP), an enzyme that breaks down skin tissues by these inflammatory factors, increases NO (nitric oxide) by inducible nitric oxide synthase (iNOS) Production is known to increase. In other words, the biosynthesis of the substrate material is reduced by the reduction of cellular activity and micro-inflammation due to naturally occurring endogenous aging, and by external factors such as the increase of stress caused by various harmful environments and the increase of reactive oxygen species caused by sunlight. As a result, the decomposition and degeneration of the matrix material are accelerated, and the skin matrix is destroyed and thinned, resulting in various symptoms of skin aging. Therefore, it is a reality that many researches have been conducted on active ingredients that can prevent and improve such aging phenomena.

On the other hand, Gelidium amansii is a red algae of the red algae plant, which consists mostly of fiber and agar, and contains natural pigments, minerals and vitamins. Korean Unexamined Patent Publication No. 10-2003-0033480 has been disclosed for processed foods containing wild herbs.

Seaweed (Undaria pinnatifida) is also brown seaweed with brown seaweed kelp. It is rich in dietary fiber, potassium, calcium and iodine and widely used in food.

Wheat germ is also a flowering and monocotyledonous plant. Grain sprouts, such as wheat germ, wheat and barley, are reported to have nutrients such as vegetables before they grow into stems and have completely different grains and ingredients. In addition, wheat germ is reported to contain various vitamins, 82 minerals, 30 yeasts, and 17 amino acids.

In addition, bergamot is an evergreen shrub with dicotyledonous leafy rats. Bergamot essential oil is a colorless liquid, a citrus oil with a fresh, tangy scent that helps to stabilize the mind, help breathing, and release tension muscles caused by mental stress.

The present inventors have completed the present invention by discovering a natural product that is harmless to the human body and has excellent synergistic effect on the antioxidant effect and wrinkle improvement effect among the natural extracts widely used in foods and the like.

It is an object of the present invention to provide a cosmetic composition having an antioxidant activity containing a mixed extract of wormwood, wakame and wheat germ.

It is another object of the present invention to provide a cosmetic composition for improving wrinkles containing a mixed extract of radish, wakame and wheat germ.

In order to achieve the above object, one embodiment of the present invention is to provide a cosmetic composition having an antioxidant activity containing aspen extract, wakame extract and wheat germ extract as an active ingredient.

In order to obtain the woodworm extract of the present invention, although it can be extracted by any seaweed extraction method known in the art at the time, the dry woodfish can be extracted by immersion in the extraction solvent after grinding. The extraction solvent may be water, alcohol, or a mixture thereof, and the alcohol may be a C ₁ to C ₃ lower alcohol, ethanol or methanol, but is not limited thereto. The extracting solvent may be extracted by adding 2 to 10 times to the total amount of loot, and may be extracted by adding 3 to 8 times, but is not limited thereto. In addition, the extraction temperature may be 30 ~ 100 ℃, may be 40 ~ 80 ℃, but is not limited thereto. This is because the maintenance of the temperature is effective for the prevention of rot, discoloration and odor. In addition, the extraction time may be 5 to 20 hours, may be 10 to 15 hours, but is not limited thereto. In addition, the number of extraction may be repeatedly extracted 1 to 5 times, it may be extracted repeatedly 2 to 3 times, but is not limited thereto. Extraction method of the loot can be any conventional extraction method in the art, such as hot water extraction, bath extraction, ultrasonic extraction, Soxhlet extraction and reflux cooling extraction method can be used.

In order to obtain the wakame and wheat germ extract of the present invention can be extracted by the same method as the wood starfish.

The loot, seaweed and wheat germ may be contained in a composition having antioxidant activity at a weight ratio of 1 to 10: 1 to 10: 1 to 10, respectively. Preferably it may be contained in a composition having antioxidant activity in a weight ratio of 2 to 8: 2 to 8: 2 to 8, most preferably in the same weight ratio. However, the content ratio may be mixed in various weight ratios according to the characteristics of the product.

The wormwood extract, wakame extract and wheat germ extract have very good radical scavenging ability similar to vitamin C in terms of DPPH radical scavenging activity, as well as a superoxide dismutase which plays an important role in removing free radicals in vivo. SOD) and catalase were confirmed to have an active protective effect (Tables 2 to 4 and FIGS. 1 to 3).

In addition, one embodiment of the present invention provides a cosmetic composition having an antioxidant activity containing loot, wakame, wheat germ and bergamot as an active ingredient.

The wormwood, seaweed, wheat germ and bergamot may be contained in a composition having antioxidant activity in a weight ratio of 1 to 10: 1 to 10: 1 to 10: 1 to 10, respectively. Preferably it may be contained in a composition having antioxidant activity in a weight ratio of 2 to 8: 2 to 8: 2 to 8: 2 to 8, most preferably in the same weight ratio. However, the content ratio may be mixed in various weight ratios according to the characteristics of the product.

In addition, one embodiment of the present invention provides a cosmetic composition for improving wrinkles containing loot, wakame and wheat germ as active ingredients. In addition, the cosmetic composition for improving wrinkles may additionally contain bergamot.

In order to obtain the wakame extract of the present invention can be extracted by the same method as the above.

The wormwood, seaweed and wheat germ extract may be contained in the cosmetic composition for improving wrinkles at a weight ratio of 1 to 10: 1 to 10: 1 to 10, respectively. Preferably it may be contained in a composition having antioxidant activity in a weight ratio of 2 to 8: 2 to 8: 2 to 8.

In addition, the wormwood, seaweed, wheat germ and bergamot extract may be contained in the cosmetic composition for improving wrinkles at a weight ratio of 1 to 10: 1 to 10: 1 to 10: 1 to 10, respectively. Preferably it may be contained in a composition having antioxidant activity in a weight ratio of 2 to 8: 2 to 8: 2 to 8: 2 to 8, most preferably in the same weight ratio. However, the content ratio may be mixed in various weight ratios according to the characteristics of the product.

In addition, one embodiment of the present invention provides an anti-aging and anti-wrinkle cosmetics containing a mixed extract of wormwood, seaweed, wheat germ and bergamot extract. The mixed extract may be contained in an total weight ratio of 1 to 30% by weight, may be contained in 5 to 20% by weight.

In addition, the cosmetic composition comprising the extract of the present invention may include, in addition to the extract, conventional adjuvants and carriers such as antioxidants, stabilizers, solubilizers, vitamins, pigments and flavorings, and may be formulated with a carrier. . Cosmetic compositions of the invention can be prepared in any formulation conventionally prepared in the art and include, for example, solutions, suspensions, emulsions, pastes, gels, creams, lotions, powders, soaps, surfactant-containing It may be formulated as a cleansing, oil, powder foundation, emulsion foundation, wax foundation, spray, and the like, but is not limited thereto. More specifically, it may be prepared in the form of a flexible lotion, nutrition lotion, nutrition cream, massage cream, essence, eye cream, hair tonic, shampoo, rinse, cleansing cream, cleansing foam, cleansing water, pack, spray and powder .

When the formulation of the present invention is a paste, cream or gel, animal carriers, vegetable oils, waxes, paraffins, starches, trachants, cellulose derivatives, polyethylene glycols, silicones, bentonites, silicas, talc or zinc oxide may be used as carrier components. Can be.

In the case where the formulation of the present invention is a powder or a spray, lactose, talc, silica, aluminum hydroxide, calcium silicate or polyamide powder may be used as a carrier component. Especially, in the case of a spray, a mixture of chlorofluorohydrocarbons, propane / Propane or dimethyl ether.

When the formulation of the present invention is a solution or emulsion, a solvent, solubilizer or emulsifier is used as the carrier component, such as water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, propylene glycol, 1 Fatty acid esters of, 3-butylglycol, glycerol aliphatic ester, polyethylene glycol or sorbitan.

When the formulation of the present invention is a suspension, liquid carrier diluents such as water, ethanol or propylene glycol, suspending agents such as ethoxylated isostearyl alcohol, polyoxyethylene sorbitol esters and polyoxyethylene sorbitan esters, and microcrystals are used as carrier components. Castle cellulose, aluminum metahydroxy, bentonite, agar or tracant and the like can be used.

When the formulation of the present invention is a surfactant-containing cleansing, the carrier component is an aliphatic alcohol sulfate, an aliphatic alcohol ether sulfate, a sulfosuccinic acid monoester, isethionate, an imidazolinium derivative, methyltaurate, sarcosinate, fatty acid amide. Ether sulfates, alkylamidobetaines, aliphatic alcohols, fatty acid glycerides, fatty acid diethanolamides, vegetable oils, lanolin derivatives or ethoxylated glycerol fatty acid esters and the like can be used.

The cosmetic composition containing a mixture of wormwood extract, wakame extract, wheat germ extract and bergamot extract according to the present invention not only has an excellent radical scavenging effect, but also protects enzyme activity such as SOD or catalase, which plays an important role in the antioxidant system. effective. In addition, since it is effective in improving skin wrinkles, it can be used not only as an antioxidant cosmetic composition and a cosmetic composition for improving wrinkles, but also useful as an anti-aging cosmetic composition.

Figure 1 shows the DPPH radical scavenging activity of extracts of Locust, Wakame, Wheat Germ and Bergamot, respectively, and mixtures thereof.
Figure 2 shows the protective effect of SOD activity of the extracts of Locust, wakame, wheat germ and bergamot, respectively, and mixtures thereof.
Figure 3 illustrates the catalase protective effect of extracts of Locust, Wakame, Wheat Germ and Bergamot, respectively, and mixtures thereof.
Figure 4 shows the effect of improving the wrinkles of the extracts of Locust, seaweed, wheat germ and bergamot and mixtures thereof.

Hereinafter, the present invention will be described in more detail with reference to the following examples. However, the following examples are only for illustrating the present invention, and the scope of the present invention is not limited thereto.

< Example  1> Preparation of Buttercup Extract

1 kg of dried woodfish was chopped to an appropriate size and placed in an extraction tank, and 5 L of distilled water was added thereto, heated at 70 to 75 ° C. for 3 hours, extracted three times, filtered through a 400 mesh filter cloth, and filtered with a filter of 0.45 μm. The filtrate was concentrated using a distillation under reduced pressure (EYELA, JP / N-1000) and then lyophilized to obtain 112 g of Locust fern extract.

< Example  2> Preparation of Seaweed Extract

1 kg of dried wakame was chopped to an appropriate size and added to the extraction tank, and 5 L of distilled water was added thereto, heated at 70 to 75 ° C. for 3 hours, extracted three times, filtered through a 400 mesh filter cloth, and filtered through a 0.45 μm filter. The filtrate was concentrated using a distillation under reduced pressure (EYELA, JP / N-1000) and then lyophilized to obtain 103 g of seaweed extract.

< Example  3> Preparation of Wheat Germ Extract

To 500 g of dried wheat germ, 5 liters of distilled water was added, heated at 70 to 75 ° C. for 3 hours, extracted three times, filtered through a 400 mesh filter cloth, and filtered using a 0.45 μm filter. The filtrate was dried under reduced pressure (EYELA, JP / N). -1000) was concentrated and freeze-dried to obtain 90 g of wheat germ extract.

< Example  4> Bergamot  Preparation of extract

The dried bergamot leaves were pulverized, 500 g of pulverized bergamot was added to 5 L of tertiary distilled water, and heated in a bath at 75 ° C for 24 hours. This was filtered through a paper filter Watman # 2 to remove solids, and the filtrate was dried under reduced pressure using a vacuum distillation machine (EYELA, JP / N-1000) to obtain 38 g of bergamot extract.

< Example  5-12> Locust, seaweed, wheat germ and Bergamot  Preparation of extract

A mixed extract obtained by mixing each extract of Locust, seaweed, wheat germ and bergamot in a weight ratio as shown in Table 1 below. Specifically, each extract obtained in Examples 1 to 4 was dissolved in distilled water at a concentration of 10 mg / ml, and then mixed extracts were prepared by mixing the respective extract aqueous solutions so that the weight ratio of each extract was Table 1.

Weight ratio of each extract component in mixed extract Example Mugwort Seaweed Wheat germ Bergamot 5 50 50 0 0 6 50 0 50 0 7 50 00 0 50 8 0 50 50 0 9 0 50 0 50 10 35 35 30 0 11 35 35 0 30 12 25 25 25 25

< Experimental Example 1 > Starfish, seaweed, wheat germ and Bergamot  Extract Radical Scatters  Measure

Antioxidation was performed by performing the DPPH (1,1-diphenyl-2-picryl-hydrazyl) method to confirm the antioxidant activity of the woodworm, wakame, wheat germ and bergamot extracts prepared in the above-described method and the extract of bergamot and mixed extract thereof. Activity was measured (Taco, T et al., Biosci. Biotech. Biochem. 58: 1780-1783, 1994; Na, M. K et al., Nat Prod. Sic. 8: 26-29, 2002). DPPH is a relatively stable free radical, which exhibits a maximum absorbance at 517 nm when present in the radical state, and loses absorbance when it is eliminated.

Specifically, woodworm, wakame, wheat germ and bergamot extract and mixed extracts thereof were diluted in a 10 well step at a concentration of 500 μg / ml in a 96 well plate using 70% ethanol solution, and then prepared as a 100 μM ethanol solution. DPPH (1,1-diphenyl-2-picryl-hydrazyl) was added to adjust the total volume of the solution to 200 μl. After, 37 ℃ in then reacted for 30 minutes for the control group was not added to the sample by measuring the absorbance in 520nm ELISA reader were calculated according to equation 1, IC of the sample the concentration of which clear the DPPH radical 50% ₅₀ ( inhibitory Concentration) (Table 2 and Figure 1).

Starfish, seaweed, wheat germ and Bergamot  Extract Radical Scatters ( IC ₅₀ Unit μg / ml) IC ₅₀ (占 퐂 / ml) Example 1 8.45 Example 2 7.46 Example 3 4.51 Example 4 5.21 Example 5 7.23 Example 6 3.56 Example 7 4.98 Example 8 3.77 Example 9 5.11 Example 10 2.21 Example 11 2.87 Example 12 1.34 Vitamin C 2.24

< Experimental Example 2 > Starfish, Seaweed, Wheat Germ and Bergamot  Mixed extract Human skin cell line  About Antioxidant system  Protective effect measurement

In this experiment, as a cell line, Dr. Human keratinocytes HaCaT cell line (Human keratinocytes HaCaT cell line) sold from Fusenig was used. After dispensing the cell lines into 6.0 X 10 ⁶ cells in a 150 X 150 culture plate and incubating for 1 day, the cells were cultured with DMEM (Dulbeco's modified eagle's medium, GIBCO BRL, Life Technologues) containing fetal bovine serum (FBS). Inoculate each medium into 1 μg / ml, 10 μg / ml and 50 μg / ml concentrations of Locust, wakame, wheat germ and bergamot mixed extract in the medium, at 37 ° C. and 5% CO ₂ . Incubated for 1 day. 1X phosphate buffer solution (PBS, phosphate buffered saline, Sigma, Inc., St. Louis, MO, USA) was used for washing after incubation. After incubation, UV light was treated with an intensity of 30 mJ / cm 2 using an ultraviolet B (UVB) lamp (Model: F15T8, UVB 15W, Sankyo Dennki Co., Japan), and at 37 ° C., 5% CO ₂ . After culturing for 1 day, the harvest was harvested and used to measure antioxidant defenses. Vitamin C was used as a positive control to compare the results, the concentration of vitamin C was 10 ㎍ / ㎖.

Superoxide dismutase (SOD) and catalase were measured as antioxidant defense factors, respectively. Superoxide dismutase is described by McCord's method [J. Biol. Chem. (1969) 244: 6049-6055] and catalase was determined by Budhuin's method [Biochem. J. (1964) 92: 179-184].

The activity of the intracellular antioxidant system was expressed as the activity compared to this value in terms of the activity of the control group not irradiated with UVB was calculated by the following equation 2, the results are shown in Table 3.

A: activity of control group

B: activity of UVB control group and each experimental group

SOD  And Catalase  Protective effect Experimental group Superoxide Dismutase Catalase Content (µg / mL) One 10 50 One 10 50 Control group 100 100 100 100 100 100 UVB 48.2 48.2 48.2 61.4 61.4 61.4 Vitamin C 84.5 86.8 Example 1 60.2 65.7 67.3 65.3 67.2 71.4 Example 2 61.2 68.2 71.2 60.2 66.7 69.2 Example 3 70.2 72.3 75.4 63.2 70.1 74.8 Example 4 63.8 68.4 69.8 65.2 67.1 68.2 Example 5 63.4 69.4 72.4 63.2 67.8 73.2 Example 6 75.8 82.3 83.2 68.5 79.2 82.1 Example 7 62.8 72.8 74.3 66.2 68.1 71.3 Example 8 76.2 80.1 81.4 69.7 76.4 82.4 Example 9 65.2 70.4 73.2 64.2 68.8 72.1 Example 10 80.7 83.4 87.4 75.4 82.8 86.4 Example 11 70.3 76.4 82.4 68.2 75.4 80.2 Example 12 82.4 85.2 89.4 84.3 97.3 91.2

* The data is the average value measured three times.

In addition, the protective effect of the superoxide dismutase (SOD) on the intracellular antioxidant system of the experimental group treated with extracts and mixed extracts of woodworm, wakame, wheat germ and bergamot compared to the UVB irradiated group It was measured by dividing the effect, the active protective effect of catalase, and the measurement result was expressed by the following formula (3), and the results are shown in Figures 2 and 3 below.

A: activity of the control group

B: activity of UVB treatment group

C: activity of each experimental group

< Experimental Example 3 > Wrinkle improvement

Skin wrinkle improvement effects of Examples 5, 10 and 12 and Comparative Examples 1 and 2 according to the present invention were evaluated in humans. The group of 75 women in their 30s to 40s was divided into 5 groups of 15 people each of the groups of Examples 10 and 12, Comparative Examples 1 and 2, and Example 5, which were considered to have the best effect on the designated eye area for 6 weeks twice daily. The emulsions were each applied. After 6 weeks, the wrinkles around the face were collected with a silicone resin copy (replica) before and after 6 weeks of use, and the skin fine wrinkles and skin image analyzer were used to compare the condition of fine wrinkles. The results are shown in Table 4 below.

Experimental group
Average fine wrinkle depth
Before use  % Reduction in contrast wrinkles
Before use 6 weeks after use Comparative Example 1 No additives 20.4 20.1 1.47 Comparative Example 2 Vitamin C 5.0 wt% 20.6 16.8 18.45 Example 5 Starfish and Wakame Extract 5.0 wt% 20.5 17.8 13.17 Example 10 5.0% by weight of starfish, seaweed and wheat germ 20.7 16.5 20.29 Example 12 Loach, seaweed, wheat germ and bergamot 5.0 wt% 20.7 15.2 26.57

< Formulation example  1> flexible lotion

Butylene glycol, glycerin, polyoxyethylene hydrogenated pirage oil, betaine, citric acid, sodium citrate, and preservatives were added to the purified water, followed by stirring and dissolving. To the mixture was added to the mixed extract of wormwood, wakame seaweed, wheat germ and bergamot according to the present invention and sufficiently stirred to prepare a flexible lotion containing the mixed extract according to the present invention. The content of each component is shown in Table 6 below.

ingredient Content (% by weight) Loach, Seaweed, Wheat Germ and Bergamot
Mixed extract 4.0 Butylene glycol 3.5 glycerin 2.5 Polyoxyethylene hardened castor oil 0.1 ethanol 2.5 Betaine 1.0 Citric acid 0.01 Sodium citrate 0.03 antiseptic a very small amount Spices a very small amount Purified water Balance

< Formulation example  2> nutrition lotion

Loot, seaweed, wheat germ and bergamot mixed extract, butylene glycol, glycerin, carboxyvinyl polymer, arginine, preservative and purified water according to the present invention were heated with stirring at 70 ~ 75 ℃. Squalane, butylene glycol dicaprylate / dicaprate, sorbitan stearate, polysorbate 60, glyceryl stearate, and stearyl glycerate mixture, which were stirred and heated at 75 ° C. to 80 ° C. were added thereto, followed by emulsification. After stirring, by adding a fragrance while cooling to about 45 ℃ while stirring, and then cooled to 30 ℃ and aged to prepare a nutrient lotion containing the mixed extract according to the present invention. Table 7 shows the content of each component.

ingredient Content (% by weight) Loach, Seaweed, Wheat Germ and Bergamot
Mixed extract 6.0 Butylene glycol 8.0 glycerin 5.0 Squalane 4.0 Butylene Glycol Dicaprylate / Dicaprate 5.0 Sorbitan stearate 1.5 Polysorbate 60 1.0 Glyceryl stearate 0.5 Stearyl glycyrrhetinate 0.2 Carboxyvinyl polymer 0.1 Arginine 0.1 antiseptic a very small amount Spices a very small amount Purified water Balance

< Formulation example  3> nutrition essence

Cytocyterol, polyglyceryl-2-oleate, ceramide, ceteareth-4 and cholesterol are stirred and mixed, and then the wormwood, seaweed, wheat germ and bergamot mixed extract according to the present invention, dicetyl phosphate, concentrated glycerin and purified water After the mixture was added and emulsified, the mixture was cooled to 45 ° C. while stirring, and then flavored with addition of agitation, followed by cooling to 30 ° C. for aging. Carboxyvinyl polymer, xanthan gum and preservatives were added thereto, stabilized, and aged to prepare a nutritional essence containing the mixed extract according to the present invention. The content of each component is shown in Table 8 below.

ingredient Content (% by weight) Loach, Seaweed, Wheat Germ and Bergamot
Mixed extract 7.0 Sitosterol 1.7 Polyglyceryl-2-oleate 1.5 Ceramide 0.5 Setares-4 1.2 cholesterol 1.5 Dicetyl phosphate 0.4 Concentrated glycerin 5.0 Carboxyvinyl polymer 0.2 Xanthan gum 0.2 antiseptic a very small amount Spices a very small amount Purified water Balance

< Formulation example  4> nutrition cream

1,3-butylene glycol, glycerine, hydrogenated resin, octyldodecanol, trioctanoin, stearic acid, polysorbate 60, and sorbitan sesquioleate are stirred and mixed, Emulsified by adding a loot, seaweed, wheat germ and bergamot mixed extract according to the invention, triethanolamine, dimethicone, EDTA, glycerin and purified water mixed solution, and when the mixture is cooled to 45 ℃ while stirring, stirring and cooling to 30 ℃ And aged. Xanthan gum and preservatives were added thereto, stabilized, and aged to prepare a nourishing cream containing the mixed extract according to the present invention. Table 9 shows the content of each component.

ingredient Content (% by weight) Loach, Seaweed, Wheat Germ and Bergamot
Mixed extract 10.0 1,3-butylene glycol 3.0 glycerin 3.0 Hydrogenated lecithin 1.0 Octyldodecanol 3.0 Trioctanoin 2.0 Stearic Acid 1.5 Cetostearyl alcohol 2.0 Polysorbate 60 1.5 Sorbitan sesquioleate 2.0 Dimethicone 3.0 Antioxidant 0.3 Xanthan gum 0.2 Triethanolamine 0.1 EDTA 0.1 Purified water Balance

< Formulation example  5> pack

Glycerin, 1,3-butylene glycol, sodium hyaluronate, glycine, and polyacrylamide are stirred and mixed, and then the wormwood, wakame, wheat germ and bergamot mixed extract according to the present invention, squalene, dimethicone, triethanolamine, and After adding EDTA emulsion to emulsify and cooling to 45 degreeC with stirring, it adds fragrance | flavor and stirred, and cooled to 30 degreeC, and aged. Xanthan gum and preservatives were added thereto, stabilized, and then aged to prepare a pack by applying the mixed extract according to the present invention to a nonwoven fabric.

ingredient Content (% by weight) Loach, Seaweed, Wheat Germ and Bergamot
Mixed extract 8.0 glycerin 7.0 1,3-butylene glycol 3.0 Squalene 3.0 Dimethicone 3.0 Sodium hyuronate 0.1 Glycine 2.0 Polyacrylamide 5.0 Antioxidant 0.3 Triethanolamine 0.1 EDTA 0.1 Purified water Balance

Claims (10)

Cosmetic composition having an antioxidant activity containing the wormwood extract, wakame extract and wheat germ extract as an active ingredient. The cosmetic composition of claim 1, wherein the woodworm, wakame extract, and wheat germ extract are each contained in a weight ratio of 1 to 10: 1 to 10: 1 to 10. The cosmetic composition of claim 1 having an antioxidant activity further comprising bergamot extract. The cosmetic composition of claim 1, wherein the woodworm extract, wakame extract, wheat germ extract, and bergamot extract are contained in a weight ratio of 1 to 10: 1 to 10: 1 to 10: 1 to 10, respectively. A cosmetic composition for improving wrinkles, which contains woodworm extract, wakame extract and wheat germ extract as an active ingredient. The cosmetic composition for improving wrinkles according to claim 5, further comprising bergamot extract. The cosmetic composition for improving wrinkles according to claim 6, wherein the woodworm extract, wakame extract, wheat germ extract, and bergamot extract are each contained in a weight ratio of 1 to 10: 1 to 10: 1 to 10: 1 to 10. The cosmetic composition according to any one of claims 1 to 7, wherein the woodworm extract, wakame extract, wheat germ extract, and bergamot extract are extracted with water, C ₁ to C ₃ lower alcohol or a mixture thereof. A cosmetic for improving wrinkles, comprising the composition of claim 1. The cosmetic for wrinkle improvement of claim 9, wherein the cosmetic is any one selected from the group consisting of softening cream, nutrient cream, nutrient essence, nutrition cream, and pack.

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