CN107208047B - 靶向b-细胞成熟抗原的嵌合抗原受体及其用途 - Google Patents
靶向b-细胞成熟抗原的嵌合抗原受体及其用途 Download PDFInfo
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111021056.1A CN113603795A (zh) | 2014-12-05 | 2015-12-04 | 靶向b-细胞成熟抗原的嵌合抗原受体及其用途 |
| CN202111021055.7A CN113698497A (zh) | 2014-12-05 | 2015-12-04 | 靶向b-细胞成熟抗原的嵌合抗原受体及其用途 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462088309P | 2014-12-05 | 2014-12-05 | |
| US62/088,309 | 2014-12-05 | ||
| PCT/US2015/064112 WO2016090320A1 (en) | 2014-12-05 | 2015-12-04 | Chimeric antigen receptors targeting b-cell maturation antigen and uses thereof |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202111021055.7A Division CN113698497A (zh) | 2014-12-05 | 2015-12-04 | 靶向b-细胞成熟抗原的嵌合抗原受体及其用途 |
| CN202111021056.1A Division CN113603795A (zh) | 2014-12-05 | 2015-12-04 | 靶向b-细胞成熟抗原的嵌合抗原受体及其用途 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN107208047A CN107208047A (zh) | 2017-09-26 |
| CN107208047B true CN107208047B (zh) | 2021-09-21 |
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| CN202111021056.1A Pending CN113603795A (zh) | 2014-12-05 | 2015-12-04 | 靶向b-细胞成熟抗原的嵌合抗原受体及其用途 |
| CN202111021055.7A Pending CN113698497A (zh) | 2014-12-05 | 2015-12-04 | 靶向b-细胞成熟抗原的嵌合抗原受体及其用途 |
| CN201580075540.9A Active CN107208047B (zh) | 2014-12-05 | 2015-12-04 | 靶向b-细胞成熟抗原的嵌合抗原受体及其用途 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202111021056.1A Pending CN113603795A (zh) | 2014-12-05 | 2015-12-04 | 靶向b-细胞成熟抗原的嵌合抗原受体及其用途 |
| CN202111021055.7A Pending CN113698497A (zh) | 2014-12-05 | 2015-12-04 | 靶向b-细胞成熟抗原的嵌合抗原受体及其用途 |
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| JP6197039B2 (ja) | 2012-08-24 | 2017-09-13 | イェール ユニバーシティーYale University | ハイスループット多重検出用システム、装置及び方法 |
| US10126301B2 (en) | 2013-02-08 | 2018-11-13 | Institute For Myeloma & Bone Cancer Research | Diagnostic, prognostic, and monitoring methods for multiple myeloma, chronic lymphocytic leukemia, and B-cell non-hodgkin lymphoma |
| CN106659757B (zh) | 2014-04-24 | 2022-01-28 | 利兰斯坦福初级大学董事会 | 白介素2的超级激动剂、部分激动剂和拮抗剂 |
| JP7054622B2 (ja) | 2014-07-21 | 2022-04-14 | ノバルティス アーゲー | ヒト化抗bcmaキメラ抗原受容体を使用した癌の処置 |
| WO2016090148A1 (en) | 2014-12-03 | 2016-06-09 | IsoPlexis Corporation | Analysis and screening of cell secretion profiles |
| KR102701479B1 (ko) | 2014-12-05 | 2024-09-03 | 메모리얼 슬로안 케터링 캔서 센터 | B-세포 성숙화 항원을 표적화하는 항체 및 사용 방법 |
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| EP3227432B1 (en) | 2014-12-05 | 2023-10-11 | Memorial Sloan Kettering Cancer Center | Chimeric antigen receptors targeting b-cell maturation antigen and uses thereof |
| US11353448B2 (en) | 2015-02-13 | 2022-06-07 | California Institute Of Technology | Methods and compositions for quantifying metabolites and proteins from single cells |
| SG11201707089WA (en) | 2015-04-13 | 2017-10-30 | Pfizer | Chimeric antigen receptors targeting b-cell maturation antigen |
| DK3298033T4 (da) | 2015-05-18 | 2023-10-02 | Tcr2 Therapeutics Inc | Sammensætninger og medicinske anvendelser til tcr-reprogrammering under anvendelse af fusionsproteiner |
| ES2898329T3 (es) | 2016-01-12 | 2022-03-07 | Oncotracker Inc | Métodos mejorados para supervisar el estado inmunitario de un sujeto |
| AR108067A1 (es) | 2016-04-01 | 2018-07-11 | Kite Pharma Inc | Moléculas de unión y métodos de uso de los mismos |
| JP7109789B2 (ja) | 2016-08-02 | 2022-08-01 | ティーシーアール2 セラピューティクス インク. | 融合タンパク質を使用したtcrの再プログラム化のための組成物及び方法 |
| WO2018049418A1 (en) * | 2016-09-12 | 2018-03-15 | IsoPlexis Corporation | System and methods for multiplexed analysis of cellular and other immunotherapeutics |
| CA3036745A1 (en) | 2016-10-07 | 2018-04-12 | TCR2 Therapeutics Inc. | Compositions and methods for t-cell receptors reprogramming using fusion proteins |
| EP4036578A1 (en) | 2016-11-11 | 2022-08-03 | Isoplexis Corporation | Compositions and methods for the simultaneous genomic, transcriptomic and proteomic analysis of single cells |
| US11525783B2 (en) | 2016-11-22 | 2022-12-13 | IsoPlexis Corporation | Systems, devices and methods for cell capture and methods of manufacture thereof |
| CA3044593A1 (en) | 2016-11-22 | 2018-05-31 | TCR2 Therapeutics Inc. | Compositions and methods for tcr reprogramming using fusion proteins |
| EP3567049A4 (en) | 2016-12-28 | 2020-08-26 | Green Cross Lab Cell Corporation | CHEMERICAL ANTIGENIC RECEPTOR AND NATURAL KILLER CELLS EXPRESSING THE SAME |
| WO2018144535A1 (en) | 2017-01-31 | 2018-08-09 | Novartis Ag | Treatment of cancer using chimeric t cell receptor proteins having multiple specificities |
| WO2018151836A1 (en) | 2017-02-17 | 2018-08-23 | Fred Hutchinson Cancer Research Center | Combination therapies for treatment of bcma-related cancers and autoimmune disorders |
| IL310182A (en) | 2017-04-26 | 2024-03-01 | Eureka Therapeutics Inc ׂ A Delaware Corp | Structures of chimeric antibody/T-cell receptor and uses thereof |
| EP3615055A1 (en) | 2017-04-28 | 2020-03-04 | Novartis AG | Cells expressing a bcma-targeting chimeric antigen receptor, and combination therapy with a gamma secretase inhibitor |
| US20200179511A1 (en) | 2017-04-28 | 2020-06-11 | Novartis Ag | Bcma-targeting agent, and combination therapy with a gamma secretase inhibitor |
| PT3618842T (pt) | 2017-05-01 | 2024-01-12 | Juno Therapeutics Inc | Combinação de uma terapia celular e de um composto imunomodulador |
| EP3621981A2 (en) | 2017-05-12 | 2020-03-18 | CRISPR Therapeutics AG | Materials and methods for engineering cells and uses thereof in immuno-oncology |
| US11166985B2 (en) | 2017-05-12 | 2021-11-09 | Crispr Therapeutics Ag | Materials and methods for engineering cells and uses thereof in immuno-oncology |
| WO2018231944A1 (en) * | 2017-06-13 | 2018-12-20 | Berenson James R | Diagnostic, prognostic, and monitoring methods for solid tumor cancers |
| US11542312B2 (en) * | 2017-06-19 | 2023-01-03 | Medicenna Therapeutics, Inc. | IL-2 superagonists in combination with anti-PD-1 antibodies |
| ES2992909T3 (en) | 2017-08-09 | 2024-12-19 | Juno Therapeutics Inc | Methods and compositions for preparing genetically engineered cells |
| MA49979A (fr) | 2017-08-09 | 2020-06-17 | Juno Therapeutics Inc | Procédés de production de compositions de cellules génétiquement modifiées et compositions associées |
| WO2019051335A1 (en) | 2017-09-07 | 2019-03-14 | Juno Therapeutics, Inc. | METHODS OF IDENTIFYING CELLULAR CHARACTERISTICS RELATED TO RESPONSES ASSOCIATED WITH CELL THERAPY |
| EP3692066A2 (en) | 2017-09-14 | 2020-08-12 | GlaxoSmithKline Intellectual Property Development Limited | Combination treatment for cancer |
| BR112020005079A2 (pt) | 2017-09-14 | 2020-09-15 | Glaxosmithkline Intellectual Property Development Limited | tratamento de combinação para câncer |
| US20200254093A1 (en) | 2017-09-14 | 2020-08-13 | Glaxosmithkline Intellectual Property Development Limited | Combination treatment for cancer |
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| US12031975B2 (en) | 2017-11-01 | 2024-07-09 | Juno Therapeutics, Inc. | Methods of assessing or monitoring a response to a cell therapy |
| US11564946B2 (en) | 2017-11-01 | 2023-01-31 | Juno Therapeutics, Inc. | Methods associated with tumor burden for assessing response to a cell therapy |
| PL3703750T3 (pl) | 2017-11-01 | 2025-04-07 | Juno Therapeutics, Inc. | Chimeryczne receptory antygenowe specyficzne dla antygenu dojrzewania komórek b i kodujące polinukleotydy |
| CN107557342A (zh) * | 2017-11-02 | 2018-01-09 | 广东万海细胞生物科技有限公司 | 一种CAR‑Treg 细胞的制备方法及其应用 |
| MX2020004568A (es) | 2017-11-06 | 2020-10-05 | Juno Therapeutics Inc | Combinación de una terapia celular y un inhibidor de gamma secretasa. |
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