CN107074854A - 咪唑并[4,5‑c]吡啶衍生的SSAO抑制剂 - Google Patents
咪唑并[4,5‑c]吡啶衍生的SSAO抑制剂 Download PDFInfo
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- CN107074854A CN107074854A CN201580056357.4A CN201580056357A CN107074854A CN 107074854 A CN107074854 A CN 107074854A CN 201580056357 A CN201580056357 A CN 201580056357A CN 107074854 A CN107074854 A CN 107074854A
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- pyridine
- imidazos
- disease
- picoline
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Abstract
Description
化合物 | hERG IC50 |
10 | A |
12 | A |
15 | A |
17 | A |
18 | A |
19 | A |
21 | A |
Claims (7)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1416446.1A GB201416446D0 (en) | 2014-09-17 | 2014-09-17 | New enzyme inhibitor compounds |
GB1416446.1 | 2014-09-17 | ||
PCT/GB2015/052690 WO2016042331A1 (en) | 2014-09-17 | 2015-09-17 | Imidazo[4,5-c]pyridine derived ssao inhibitors |
Publications (2)
Publication Number | Publication Date |
---|---|
CN107074854A true CN107074854A (zh) | 2017-08-18 |
CN107074854B CN107074854B (zh) | 2019-07-19 |
Family
ID=51869761
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201580056357.4A Expired - Fee Related CN107074854B (zh) | 2014-09-17 | 2015-09-17 | 咪唑并[4,5-c]吡啶衍生的SSAO抑制剂 |
Country Status (15)
Country | Link |
---|---|
US (1) | US10065954B2 (zh) |
EP (1) | EP3194388B1 (zh) |
JP (1) | JP6556838B2 (zh) |
CN (1) | CN107074854B (zh) |
AU (1) | AU2015316610B2 (zh) |
BR (1) | BR112017005314A2 (zh) |
CA (1) | CA2961422A1 (zh) |
DK (1) | DK3194388T3 (zh) |
ES (1) | ES2745824T3 (zh) |
GB (1) | GB201416446D0 (zh) |
HU (1) | HUE045626T2 (zh) |
IL (1) | IL251164B (zh) |
PL (1) | PL3194388T3 (zh) |
PT (1) | PT3194388T (zh) |
WO (1) | WO2016042331A1 (zh) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB201304526D0 (en) * | 2013-03-13 | 2013-04-24 | Proximagen Ltd | New compounds |
GB201416444D0 (en) | 2014-09-17 | 2014-10-29 | Proximagen Ltd | New compounds |
GB201416446D0 (en) * | 2014-09-17 | 2014-10-29 | Proximagen Ltd | New enzyme inhibitor compounds |
CN107936026A (zh) * | 2017-12-23 | 2018-04-20 | 广东赛博科技有限公司 | 三唑类ssao抑制剂、制备方法及其用途 |
CN107936028A (zh) * | 2017-12-23 | 2018-04-20 | 广东赛博科技有限公司 | 一种哌嗪三唑类化合物、制备方法及其用途 |
CN108003169A (zh) * | 2017-12-23 | 2018-05-08 | 广东赛博科技有限公司 | 一种含吗啉和哌嗪三唑类化合物及其用途 |
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US10065954B2 (en) | 2018-09-04 |
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IL251164B (en) | 2020-10-29 |
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ES2745824T3 (es) | 2020-03-03 |
DK3194388T3 (da) | 2019-09-23 |
JP6556838B2 (ja) | 2019-08-07 |
HUE045626T2 (hu) | 2020-01-28 |
BR112017005314A2 (pt) | 2017-12-05 |
IL251164A0 (en) | 2017-04-30 |
CN107074854B (zh) | 2019-07-19 |
CA2961422A1 (en) | 2016-03-24 |
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