SG11201400277VA - New enzyme inhibitor compounds - Google Patents

New enzyme inhibitor compounds

Info

Publication number
SG11201400277VA
SG11201400277VA SG11201400277VA SG11201400277VA SG11201400277VA SG 11201400277V A SG11201400277V A SG 11201400277VA SG 11201400277V A SG11201400277V A SG 11201400277VA SG 11201400277V A SG11201400277V A SG 11201400277VA SG 11201400277V A SG11201400277V A SG 11201400277VA
Authority
SG
Singapore
Prior art keywords
enzyme inhibitor
inhibitor compounds
new enzyme
new
compounds
Prior art date
Application number
SG11201400277VA
Inventor
David Evans
Allison Carley
Alison Stewart
Michael Higginbottom
Edward Savory
Iain Simpson
Marianne Nilsson
Martin Haraldsson
Erik Nordling
Tobias Koolmeister
Original Assignee
Proximagen Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Proximagen Ltd filed Critical Proximagen Ltd
Publication of SG11201400277VA publication Critical patent/SG11201400277VA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
SG11201400277VA 2011-09-14 2011-09-14 New enzyme inhibitor compounds SG11201400277VA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2011/065967 WO2013037411A1 (en) 2011-09-14 2011-09-14 New enzyme inhibitor compounds

Publications (1)

Publication Number Publication Date
SG11201400277VA true SG11201400277VA (en) 2014-05-29

Family

ID=44677871

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201400277VA SG11201400277VA (en) 2011-09-14 2011-09-14 New enzyme inhibitor compounds

Country Status (12)

Country Link
US (1) US9150574B2 (en)
EP (1) EP2755974A1 (en)
JP (1) JP5796130B2 (en)
CN (1) CN103889983B (en)
AU (1) AU2011376717A1 (en)
BR (1) BR112014005793A2 (en)
CA (1) CA2847193A1 (en)
EA (1) EA201490451A1 (en)
IL (1) IL231353A0 (en)
IN (1) IN2014DN01883A (en)
SG (1) SG11201400277VA (en)
WO (1) WO2013037411A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201304527D0 (en) 2013-03-13 2013-04-24 Proximagen Ltd New compounds
GB201304526D0 (en) * 2013-03-13 2013-04-24 Proximagen Ltd New compounds
WO2014199171A1 (en) 2013-06-12 2014-12-18 Proximagen Limited New therapeutic uses of enzyme inhibitors
GB201416444D0 (en) 2014-09-17 2014-10-29 Proximagen Ltd New compounds
GB201416446D0 (en) 2014-09-17 2014-10-29 Proximagen Ltd New enzyme inhibitor compounds
GB201507031D0 (en) * 2015-04-24 2015-06-10 Proximagen Ltd New pharmaceutical salt forms
US20180360808A1 (en) 2015-12-07 2018-12-20 Benevolentai Cambridge Limited Vap-1 inhibitors for treating pain
JP2020505333A (en) * 2017-01-09 2020-02-20 アルデリックス, インコーポレイテッド Inhibitors of NHE-mediated antiport
US20210330646A1 (en) * 2018-08-27 2021-10-28 Spinogenix, Inc. Fascin binding compounds for spinogenesis
BR112021023843A2 (en) 2019-05-29 2022-01-04 Syngenta Crop Protection Ag microbiocidal derivatives
AU2022286467A1 (en) 2021-06-01 2024-01-25 Janssen Pharmaceutica Nv SUBSTITUTED PHENYL-1H-PYRROLO[2, 3-c]PYRIDINE DERIVATIVES
WO2023193790A1 (en) * 2022-04-08 2023-10-12 Janssen Pharmaceutica Nv Crystalline forms of an inhibitor of the menin/mll interaction

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6143749A (en) * 1995-06-07 2000-11-07 Abbott Laboratories Heterocyclic substituted cyclopentane compounds
DE19649460A1 (en) 1996-11-26 1998-05-28 Bayer Ag New substituted pyrazole derivatives
EA200200356A1 (en) 1999-09-14 2002-10-31 Авентис Фармасьютикалз Инк. BENZOZAZOZOLYL, PYRIDOISOXAZOZYL- AND BENZYINENYLPHENOXY DERIVATIVES USED AS ANTAGONISTS OF RECEPTOR D4
AU2002214505A1 (en) 2000-11-09 2002-05-21 Biovitrum Ab New use of 4, 5, 6, 7-tetrahydroimidazo-(4,5-c)pyridine derivatives
US6982286B2 (en) 2001-07-12 2006-01-03 Biotie Therapies Corp. Carbocyclic hydrazino inhibitors of copper-containing amine oxidases
ES2309206T3 (en) * 2001-10-02 2008-12-16 Smithkline Beecham Corporation CHEMICAL COMPOUNDS.
US7456169B2 (en) 2003-02-27 2008-11-25 Abbott Laboratories Inc. Heterocyclic kinase inhibitors
JP2007501802A (en) 2003-08-08 2007-02-01 ラ ホヤ ファーマシューティカル カンパニー Semicarbazide-sensitive amine oxidase (SSAO) and inhibitors of VAP-1-mediated adhesion useful for the treatment of disease
EA200801812A1 (en) 2003-09-17 2009-06-30 Янссен Фармацевтика Н.В. CONJUGATED HETEROCYCLIC COMPOUNDS
WO2005074603A2 (en) 2004-02-03 2005-08-18 Abbott Laboratories Aminobenzoxazoles as therapeutic agents
TW200538453A (en) 2004-04-26 2005-12-01 Bristol Myers Squibb Co Bicyclic heterocycles as kinase inhibitors
ATE524467T1 (en) 2005-04-25 2011-09-15 Merck Patent Gmbh NOVEL AZA HETEROCYCLES AS KINASE INHIBITORS
PT1906965E (en) 2005-06-22 2015-09-03 Chemocentryx Inc Azaindazole compounds and methods of use
WO2007120528A2 (en) 2006-03-31 2007-10-25 La Jolla Pharmaceutical Company Inhibitors of semicarbazide-sensitive amine oxidase (ssao) and vap-1 mediated adhesion useful for treatment and prevention of diseases
RU2461557C2 (en) 2006-04-04 2012-09-20 Файброджен, Инк. Pyrrolo- and thiazolopyridine compounds (versions) and based pharmaceutical composition
GB0610242D0 (en) 2006-05-23 2006-07-05 Novartis Ag Organic compounds
EP2124568A1 (en) 2007-01-17 2009-12-02 Merck & Co., Inc. Decahydroquinoline analogs as cb2 receptor modulators
JP2010525032A (en) 2007-05-02 2010-07-22 ノバルティス アーゲー Heterocyclic compounds and their use as pesticides
GB0725103D0 (en) 2007-12-21 2008-01-30 Glaxo Group Ltd Novel compounds
PT2240482E (en) 2008-01-31 2013-09-06 Sanofi Sa Cyclic azaindole-3-carboxamides, their preparation and their use as pharmaceuticals
WO2009108551A2 (en) * 2008-02-25 2009-09-03 H. Lundbeck A/S Heteroaryl amide analogues
EP2328895B1 (en) * 2008-09-16 2013-03-27 Proximagen Limited Pyrazolo[4,3-c]pyridine compounds and their use as inhibitors of SSAO
ES2440279T3 (en) 2008-09-16 2014-01-28 Proximagen Limited 4,5,6,7-tetrahydroimidazo [4,5-c] pyridine compounds as SSAO inhibitors
JP2012510983A (en) 2008-12-04 2012-05-17 プロキシマジェン エルティーディー Imidazopyridine compounds
JP2012211085A (en) 2009-08-12 2012-11-01 Kyowa Hakko Kirin Co Ltd Hedgehog signal inhibitor
GB201004311D0 (en) * 2010-03-15 2010-04-28 Proximagen Ltd New enzyme inhibitor compounds
GB201115853D0 (en) 2011-09-14 2011-10-26 Proximagen Ltd New enzyme inhibitor compounds

Also Published As

Publication number Publication date
CN103889983A (en) 2014-06-25
IL231353A0 (en) 2014-04-30
US9150574B2 (en) 2015-10-06
CA2847193A1 (en) 2013-03-21
JP5796130B2 (en) 2015-10-21
EP2755974A1 (en) 2014-07-23
EA201490451A1 (en) 2014-12-30
BR112014005793A2 (en) 2017-03-28
WO2013037411A1 (en) 2013-03-21
AU2011376717A1 (en) 2014-03-20
JP2015502913A (en) 2015-01-29
US20140357623A1 (en) 2014-12-04
CN103889983B (en) 2015-12-09
IN2014DN01883A (en) 2015-05-15

Similar Documents

Publication Publication Date Title
HK1257823A1 (en) Metalloenzyme inhibitor compounds
HK1198163A1 (en) Metalloenzyme inhibitor compounds
HK1198651A1 (en) Metalloenzyme inhibitor compounds
GB201004311D0 (en) New enzyme inhibitor compounds
ZA201309561B (en) Novel inhibitor compounds of phosphodiestarase type 10a
EP2723730A4 (en) Metalloenzyme inhibitor compounds
EP2683693A4 (en) Rorgammat inhibitors
ZA201306580B (en) Cyclopropylamines as lsd1 inhibitors
IL231352A0 (en) New enzyme inhibitor compounds
IL231353A0 (en) New enzyme inhibitor compounds
HK1200840A1 (en) Dpp-4 inhibitor dpp-4
HK1199252A1 (en) Inhibitors of nedd8-activating enzyme nedd8-
ZA201307496B (en) Novel rock inhibitors
HK1197057A1 (en) New lipogenesis inhibitor compounds
HK1191327A1 (en) Azaspirodecanone compounds as hsl inhibitors hsl
EP2751117A4 (en) Metalloenzyme inhibitor compounds
GB201114854D0 (en) Novel rock inhibitors
GB201114751D0 (en) Enzyme inhibition
GB201114748D0 (en) Enzyme inhibition
GB201104399D0 (en) Novel inhibitors
GB201120474D0 (en) Inhibitors
GB201004308D0 (en) New inhibitor compounds
GB201004309D0 (en) New enzyme inhibitors
GB201102030D0 (en) Trans-sialidase inhibitors
GB201109623D0 (en) Antibacterial enzyme inhibitors