CN107041862A - A kind of eye cream containing raspberry - Google Patents

A kind of eye cream containing raspberry Download PDF

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Publication number
CN107041862A
CN107041862A CN201710219004.2A CN201710219004A CN107041862A CN 107041862 A CN107041862 A CN 107041862A CN 201710219004 A CN201710219004 A CN 201710219004A CN 107041862 A CN107041862 A CN 107041862A
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CN
China
Prior art keywords
raspberry
extract
eye cream
water
parts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201710219004.2A
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Chinese (zh)
Inventor
索有瑞
王煜伟
栾广祥
王洪伦
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Northwest Institute of Plateau Biology of CAS
Original Assignee
Northwest Institute of Plateau Biology of CAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Northwest Institute of Plateau Biology of CAS filed Critical Northwest Institute of Plateau Biology of CAS
Priority to CN201710219004.2A priority Critical patent/CN107041862A/en
Publication of CN107041862A publication Critical patent/CN107041862A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/342Alcohols having more than seven atoms in an unbroken chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • A61K8/602Glycosides, e.g. rutin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/678Tocopherol, i.e. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention provides a kind of eye cream containing raspberry.The eye cream that will be prepared after raspberry Anthocyanin-rich Extract, raspberry fruit oil and the component compatibility use such as raspberry polysaccharide, the effects such as with good moisturizing, anti-aging.

Description

A kind of eye cream containing raspberry
Technical field
The present invention relates to a kind of eye cream containing raspberry.
Background technology
Raspberry (Rubus idaeus L.) also known as Rubus corchorifolius, raspberry, raspberry etc., belong to rose family rubus.Raspberry master Northern Hemisphere temperate zone and frigid zone are distributed in, its fruit is starches small aggregate fruit more, and taste sweet tea is slightly sour.Raspberry contains fruit oil, organic acid, Huang Ketone, anthocyanidin, the various active composition such as polyphenol, vitamin, mineral element, volatile oil, tannin, with high nutritive value and Medical care effect, is described as " gold fruit ".
At present, it yet there are no the report of the various active components compatibility utilization of raspberry.
The content of the invention
The invention provides a kind of eye cream containing raspberry, it contains the component of following quality proportioning:
Wherein, raspberry Anthocyanin-rich Extract is selected selected from 3.0~5.0 parts, the grease separation of raspberry fruit from 1.0~3.0 parts, raspberry polysaccharide From 5.0~10.0 parts, 1.0~3.0 parts of matrimony vine water extract, 1.0~3.0 parts of rose wate extract.
In an embodiment of the invention, following component proportioning have chosen:
Proportioning one:
Proportioning two:
Proportioning three:
Proportioning four:
Further, raspberry Anthocyanin-rich Extract be selected from 4.0 ± 0.5 parts, the grease separation of raspberry fruit from 2.0 ± 0.5 parts, raspberry it is many Sugar selected from 8.0 ± 0.5 parts, 2.0 ± 0.5 parts of matrimony vine water extract, 2.0 ± 0.5 parts of rose wate extract.The present invention is in actual use During find, if each position of raspberry to be combined and use with Lycium chinense fruit aqueous extract and rose wate extract according to the proportioning, Its skin effect is significantly better than other compatibility relationships.
Wherein, the raspberry is the fruit of rose family rubus plant.
Raspberry Anthocyanin-rich Extract used in the present invention, raspberry fruit oil, raspberry polysaccharide, Lycium chinense fruit aqueous extract and rose Water extract can be bought in commercial goods, can also be prepared according to presently disclosed technology, and the present invention one is specific real Apply in mode, the preparation method of the raspberry Anthocyanin-rich Extract is as follows:Take macroreticular resin on raspberry, extracting in water, water extract Post, is first washed with water removal of impurities, then with 60~80%v/v ethanol elutions, collect alcohol elution, be drying to obtain.
Wherein, the preparation method of the raspberry polysaccharide is as follows:Take after raspberry, petroleum ether or ether defatting, with 75%~ 95%v/v ethanol is extracted, filtering, filter residue extracting in water, after water intaking extract concentration, plus ethanol or hydrous ethanol to alcohol content reach 70%~85%v/v, it is raspberry polysaccharide to take solid content.
Wherein, the preparation method of the raspberry fruit oil is as follows:Raspberry is taken, using supercritical CO2Extraction is extracted, and is extracted Afterwards, then through two-stage decompression separation raspberry fruit oil is obtained;Wherein, extraction conditions is as follows:Extraction kettle pressure is 15~45Mpa, temperature For 30~55 DEG C, CO2Flow is that 20~60L/h, extraction time are 40~120min;Two-stage decompression separation condition is as follows:To press Power be 5~7Mpa, temperature be 40~50 DEG C as one-level decompression separation, by 3~5Mpa of pressure, temperature be 30~40 DEG C as Second depressurized is separated.
Lycium chinense fruit aqueous extract, i.e., be heated to 50~70 DEG C using water and extracted, extract solution is concentrated under reduced pressure, and is drying to obtain.
Rose wate extract, i.e., be heated to 50~70 DEG C using water and extracted, extract solution is concentrated under reduced pressure, and is drying to obtain.
Present invention also offers the preparation method of above-mentioned eye cream, it includes following operating procedure:
(1) raspberry fruit oil, xanthans, tocopherol, cetostearyl alcohol, cetearyl glucose and part water are taken, heating is stirred Mix, be uniformly dispersed;
(2) transition temperature adds raspberry Anthocyanin-rich Extract, raspberry polysaccharide, Lycium chinense fruit aqueous extract, rose to 40~50 DEG C Flower water extract, Sodium Hyaluronate, EDETATE SODIUM and remaining water, homogeneous, cooling down produce eye cream.
Prepared present invention also offers above-mentioned eye cream with replenishing water and preserving moisture, anti-aging, crease-resistant, anti-canthus pigment deposition work( Purposes in the cosmetics or medicine adornment of effect.
Present invention research is found, after the component compatibility uses such as raspberry Anthocyanin-rich Extract, raspberry fruit oil and raspberry polysaccharide The eye cream of preparation, the effects such as with good moisturizing, anti-aging, crease-resistant, anti-canthus pigment deposition.
In addition, some known skin care materials, such as pearl powder, coenzyme can also be added on the basis of the present invention, in eye cream Q10, hydrolyzed wheat protein etc..
In addition, the auxiliary materials such as appropriate natural antiseptic agent, antioxidant can also be added in composition or emulsion.
Embodiment
The preparation of the eye cream of the present invention of embodiment 1 and efficacy study
Technological process:
(1) raspberry fruit oil, xanthans, tocopherol, cetostearyl alcohol, cetearyl glucose and part water are taken, heating is stirred Mix, be uniformly dispersed;
(2) transition temperature adds raspberry Anthocyanin-rich Extract, raspberry polysaccharide, Lycium chinense fruit aqueous extract, rose to 40~50 DEG C Flower water extract, Sodium Hyaluronate, EDETATE SODIUM and remaining water, homogeneous, cooling down produce eye cream.
In order to test the moistening effect of the present invention, investigation experiment on probation has been carried out:
1. respondent:Choose aspiration trier totally 72 people of the different skin quality of areal;
2. control time:Continuous 30 days
Use product:A products:Eye cream prepared by the embodiment of the present invention 1;B products are reference examples eye cream:In reference examples eye cream Only following part is different from embodiment 1:Raspberry Anthocyanin-rich Extract 5.0g, raspberry fruit oil 4.0g, raspberry polysaccharide 5.0g, remaining is same Embodiment 1.
3. method of testing:36 people use A products, and remaining 36 people uses B products, and A product groups drop by the wayside 1, B product groups Drop by the wayside 1.After each group trier cleaning face, product is applied to eye part skin respectively, observes and investigates using effect, Trier does not know each group of composition proportion during use, using once before sleeping every night.
4. test result statistics is as follows:
Table 1
* it is good:Trier thinks that skin improves significantly effect;Typically:Trier's skin has improvement, but feels Effect is not to protrude very much;Without influence:Trier thinks that skin is without any improvement.
5. feed back conclusion:
Trier represents, two kinds of products of A, B suppress canthus pigment deposition, anti-aging, replenishing water and preserving moisture, crease-resistant, Improve eye microgroove, skin near the eyes of releiving makes it moist flexible.
In addition, the effect of A products anti-aging, moisturizing and confrontation pigment deposition is very well, it is continuous to use canthus flesh after one month Skin just occurred in that and has been obviously improved, and microgroove is reduced, and skin is flexible and gloss, and positive rating is up to 90% or so.B products have Certain wrinkle resistant moistening effect, microgroove has been reduced, and positive rating is 70~80% or so, and its effect is not as good as A products.
The preparation of the eye cream of the present invention of embodiment 2 and efficacy study
Preparation method is ibid.
The preparation of the eye cream of the present invention of embodiment 3 and efficacy study
Preparation method is ibid.
The preparation of the eye cream of the present invention of embodiment 4 and efficacy study
Preparation method is ibid.

Claims (9)

1. a kind of eye cream containing raspberry, it is characterised in that:It contains the component of following quality proportioning:
2. the eye cream according to claim 1 containing raspberry, it is characterised in that:Raspberry Anthocyanin-rich Extract be selected from 3.0~ 5.0 parts, the grease separation of raspberry fruit from 1.0~3.0 parts, raspberry polysaccharide be selected from 5.0~10.0 parts, 1.0~3.0 parts of matrimony vine water extract, rose Rare 1.0~3.0 parts of colored water extract.
3. the eye cream according to claim 2 containing raspberry, it is characterised in that:Raspberry Anthocyanin-rich Extract be selected from 4.0 ± 0.5 part, the grease separation of raspberry fruit from 2.0 ± 0.5 parts, raspberry polysaccharide be selected from 8.0 ± 0.5 parts, 2.0 ± 0.5 parts of matrimony vine water extract, rose 2.0 ± 0.5 parts of water extract of flower.
4. the eye cream according to claim 1 containing raspberry, it is characterised in that:The raspberry is planted for rose family rubus The fruit of thing.
5. the eye cream containing raspberry according to Claims 1 to 4 any one, it is characterised in that:The raspberry anthocyanin The preparation method of extract is as follows:
Macroporous resin column on raspberry, extracting in water, water extract is taken, removal of impurities is first washed with water, then with 60~80%v/v ethanol elutions, Alcohol elution is collected, is drying to obtain.
6. the eye cream containing raspberry according to Claims 1 to 4 any one, it is characterised in that:The raspberry polysaccharide Preparation method is as follows:
Take after raspberry, petroleum ether or ether defatting, extracted with 75%~95%v/v ethanol, filtering, filter residue extracting in water, water intaking After extract concentration, plus ethanol or hydrous ethanol to alcohol content reach 70%~85%v/v, and it is raspberry polysaccharide to take solid content.
7. the eye cream containing raspberry according to Claims 1 to 4 any one, it is characterised in that:The raspberry fruit oil Preparation method is as follows:
Raspberry is taken, using supercritical CO2Extraction is extracted, after extraction, then obtains raspberry fruit oil through two-stage decompression separation;Wherein, Extraction conditions is as follows:Extraction kettle pressure is that 15~45Mpa, temperature are 30~55 DEG C, CO2Flow is 20~60L/h, extraction time For 40~120min;Two-stage decompression separation condition is as follows:By 5~7Mpa of pressure, temperature is 40~50 DEG C and depressurized as one-level Separation, by 3~5Mpa of pressure, temperature is 30~40 DEG C and separated as second depressurized.
8. the preparation method of eye cream described in claim 1, it is characterised in that:It includes following operating procedure:
(1) raspberry fruit oil, xanthans, tocopherol, cetostearyl alcohol, cetearyl glucose and part water, heating stirring are taken, is divided Dissipate uniform;
(2) transition temperature adds raspberry Anthocyanin-rich Extract, raspberry polysaccharide, Lycium chinense fruit aqueous extract, rose wate to 40~50 DEG C Extract, Sodium Hyaluronate, EDETATE SODIUM and remaining water, homogeneous, cooling down produce eye cream.
9. eye cream described in claim 1~7 any one sinks in preparation with replenishing water and preserving moisture, anti-aging, crease-resistant, anti-canthus pigment Purposes in the cosmetics or medicine adornment of product effect.
CN201710219004.2A 2017-04-05 2017-04-05 A kind of eye cream containing raspberry Pending CN107041862A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710219004.2A CN107041862A (en) 2017-04-05 2017-04-05 A kind of eye cream containing raspberry

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Application Number Priority Date Filing Date Title
CN201710219004.2A CN107041862A (en) 2017-04-05 2017-04-05 A kind of eye cream containing raspberry

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CN107041862A true CN107041862A (en) 2017-08-15

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104862069A (en) * 2015-04-04 2015-08-26 青海瑶池生物科技有限公司 Raspberry fruit oil and application thereof
CN105395443A (en) * 2015-11-18 2016-03-16 关美玲 Anti-aging eye cream and preparation method thereof
CN106265286A (en) * 2016-08-31 2017-01-04 青海新泰行生物科技有限公司 A kind of cosmetic composition containing black Fructus Lycii extract and eye cream
CN106420488A (en) * 2016-11-14 2017-02-22 广州蜜妆生物科技有限公司 Regenerating nourishing anti-wrinkle eye cream

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104862069A (en) * 2015-04-04 2015-08-26 青海瑶池生物科技有限公司 Raspberry fruit oil and application thereof
CN105395443A (en) * 2015-11-18 2016-03-16 关美玲 Anti-aging eye cream and preparation method thereof
CN106265286A (en) * 2016-08-31 2017-01-04 青海新泰行生物科技有限公司 A kind of cosmetic composition containing black Fructus Lycii extract and eye cream
CN106420488A (en) * 2016-11-14 2017-02-22 广州蜜妆生物科技有限公司 Regenerating nourishing anti-wrinkle eye cream

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
周秋丽: "《现代中药基础研究与临床》", 30 June 2012, 天津科技翻译出版公司 *
孙希云等: "红树莓花色甘粗提物抗氧化性能与抑菌作用研究", 《食品工业科技》 *

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Application publication date: 20170815

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