CN105232401B - A kind of black fruit fructus lycii combination Essence and application thereof - Google Patents

A kind of black fruit fructus lycii combination Essence and application thereof Download PDF

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Publication number
CN105232401B
CN105232401B CN201510759927.8A CN201510759927A CN105232401B CN 105232401 B CN105232401 B CN 105232401B CN 201510759927 A CN201510759927 A CN 201510759927A CN 105232401 B CN105232401 B CN 105232401B
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parts
fructus lycii
essence
black fruit
fruit fructus
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CN105232401A (en
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索润德
索元德
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ZHONGKE GUOYUE HUZHOU BIOTECHNOLOGY DEVELOPMENT Co.,Ltd.
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Shanghai Zi Di Laboratory Science And Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/007Preparations for dry skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/008Preparations for oily skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention provides a kind of black fruit fructus lyciis to combine Essence, it is configured by the raw material of following parts by weight:10~25 parts of black black fruit fructus lycii Aqueous extracts, 10~16 parts of sea-buckthorn Aqueous extracts, 5~10 parts of licorice water extract, 8~12 parts of hyaluronic acid, 8~12 parts of glycerine, 4005~10 parts of polyethylene glycol PEG, 3~5 parts of elastin hydrolysis, 3~6 parts of vitamin E, 10~25 parts of deionized water.Essence of the present invention can inhibit the formation of harmful free radicals and melanin, inject nutrition for skin, so as to freckle removing and whitening, anti-aging, replenishing water and preserving moisture, make skin gloss high resilience, and the young state of health is presented.

Description

A kind of black fruit fructus lycii combination Essence and application thereof
Technical field
The present invention relates to a kind of black fruit fructus lyciis to combine Essence and application thereof.
Background technology
Presently commercially available Essence is dazzling, is divided into whitening, moisturizing, cleaning, Sage Extract, anti-ageing according to different efficacies Always, it releives, lead, mercury, benzene in most products, phenol content are exceeded, although it is glossy soft so that skin is presented State, but it is used for a long time that cuticula can be made to fall off is thinning, lead to red swelling of the skin, forms color spot, be unfavorable for skin health.
Black fruit fructus lycii and sea-buckthorn are distributed across the characteristic berry in northwest China area, they are grown in salinization wasteland, salinization In the salination ambient soil such as sand ground, growth conditions is arduous, and vitality is extremely strong, drought-enduring, the cold-resistant, high temperature resistant of energy, very precious.It is black Fruit Chinese wolfberry fruit is rich in anthocyanidin, being capable of anti-aging, beautifying face and moistering lotion.Vitamin C content is high in sea buckthorn fruit, skin can be made to be full of Vigor.Two kinds of berries all can be used as skin care item, also edible.
It is combined currently on the market still without using black fruit fructus lycii and sea-buckthorn, the Essence for being used as main skin care ingredient goes out It is existing.
Invention content
In order to increase the added value of product of black fruit fructus lycii, sea-buckthorn, the present invention plans the two and is applied in combination to prepare skin care item, However, only whether both above-mentioned combination can reach good skin care effect, someone's research yet there are no.Before inventor Phase experiment find, if only by the compatible use of both black fruit fructus lycii and sea-buckthorn, although also there is certain skin care effect, whitening, Anti-aging and other effects is not ideal enough.For this purpose, inventor passes through a large amount of experiment screening, and it is final to confirm, only in black fruit fructus lycii, sand On the basis of spine, adds Radix Glycyrrhizae and carry out compatibility, each original can be played to the maximum extent in the case of minimum raw material type The skin care effect of material.
For these reasons, the present invention is practical provides a kind of black fruit fructus lycii combination Essence, is by following parts by weight Raw material configures:
10~25 parts of black fruit fructus lycii Aqueous extracts, 10~16 parts of sea-buckthorn Aqueous extracts, 5~10 parts of licorice water extract, hyaluronic acid 8 ~12 parts, 8~12 parts of glycerine, polyethylene glycol PEG-4005~10 part, 3~5 parts of elastin hydrolysis, 3~6 parts of vitamin E, 10~25 parts of deionized water.
In a specific implementation mode of the invention, the Essence is configured by the raw material of following parts by weight:
10 parts of black fruit fructus lycii Aqueous extracts, 10 parts of sea-buckthorn Aqueous extracts, 5 parts of licorice water extract, 8 parts of hyaluronic acid, 8 parts of glycerine, PEG-4005 parts of polyethylene glycol, 3 parts of elastin hydrolysis, 3 parts of vitamin E, 10 parts of deionized water.
Wherein, the black fruit fructus lycii Aqueous extracts are prepared by the following method:
Fresh black fruit fructus lycii is taken, appropriate antioxidant, grinding or crushing is added;Deionized water is added to be uniformly mixed, filtering Or centrifugation, this step carry out 1~3 time, merge supernatant, are concentrated under reduced pressure into 1.5~2.2g/mL, preferably 2g/mL is to get black Fruit matrimony vine Aqueous extracts.
Wherein, the use of antioxidant is to protect the anthocyanidin isoreactivity ingredient in black fruit fructus lycii, and antioxidant can To select the composition of one or more of vitamin C, glutathione, lipoic acid or uric acid.
In a specific implementation mode of the invention, antioxidant selects vitamin C;Further, ascorbic dosage is 10%~50%w/w of fresh black fruit fructus lycii weight, preferably 40%w/w.
Wherein, the sea-buckthorn Aqueous extracts are prepared by the following method:
Fresh sea-buckthorn is taken, the extraction of deionization water temperature is added to take, extracting solution filtering or centrifugation, supernatant are concentrated under reduced pressure into 1.5 ~2.2g/mL, preferably 2g/mL are to get sea-buckthorn Aqueous extracts.
Wherein, the temperature that temperature extraction takes is 50~70 DEG C, is further 55~65 DEG C, a specific implementation mode of the invention It is middle to select temperature for 60 ± 2 DEG C.
Wherein, the licorice water extract is prepared by the following method:Extracting liquorice medicine materical crude slice, adds water to cook extraction, filtering or Centrifugation, supernatant are concentrated under reduced pressure into 1.0~2.0g/mL, and preferably 1.5g/mL is to get licorice water extract.
The present invention also provides use of the above-mentioned Essence in preparing the skin care item with whitening and anti-aging or moisture-keeping efficacy On the way.
The present invention is applicable in the study found that the skin care item have good skin effect for dryness, neutrality or Oily It is in extensive range.
The Essence can also be affixed to carry out skin care on other carriers again other than being directly used in skin, such as Facial mask, algae clay etc., use form can diversifications.
Black fruit fructus lycii, sea-buckthorn and Radix Glycyrrhizae are added in combination in Essence by the present invention, and use black fruit fructus lycii, sea-buckthorn, Radix Glycyrrhizae The group of compatibility two-by-two compare, the beauty functions that the present invention combines Essence greatly improve, and illustrate the present invention by black fruit fructus lycii, sea-buckthorn Synergistic function has been played with Radix Glycyrrhizae compatible use;Meanwhile the Essence is mildly non-stimulated, does not generate side effect, and to each The skin care effect of kind skin quality is all fine, has a vast market foreground.
Essence of the present invention can inhibit the formation of harmful free radicals and melanin, nutrition be injected for skin, so as to nti-freckle Whitening, anti-aging, replenishing water and preserving moisture make skin gloss high resilience, and the young state of health is presented.
Specific implementation mode
Specific embodiments of the present invention are described in detail below:
1 each embodiment Essence of table matches
Constituent Embodiment 1 Embodiment 2 Embodiment 3 Embodiment 4
Deionized water 10 parts 15 parts 20 parts 25 parts
Hyaluronic acid 8 parts 9 parts 10 parts 12 parts
Glycerine 8 parts 9 parts 10 parts 12 parts
Polyethylene glycol PEG-400 5 parts 7 parts 9 parts 10 parts
Elastin hydrolysis 3 parts 3 parts 4 parts 5 parts
Black fruit fructus lycii extracting solution 10 parts 15 parts 20 parts 25 parts
Sea-buckthorn extracting solution 10 parts 12 parts 14 parts 16 parts
Licorice extract 5 parts 7 parts 9 parts 10 parts
Vitamin E 3 parts 4 parts 5 parts 6 parts
Preparation method:Above-mentioned each ingredient mixing is packed to get Essence of the present invention.
In the present invention, black fruit fructus lycii Aqueous extracts are to prepare in the following manner:The fresh black fruit fructus lyciis of 10g accurately are weighed, To keep the stability of anthocyanidin in black fruit fructus lycii, addition 4g vitamin Cs are broken with mortar grinder, obtain black fruit fructus lycii pulp, 100mL deionized waters are added to stir evenly, filter, residue adds 100mL deionized waters again, filters, and merges supernatant twice, decompression 2g/mL is concentrated into get black fruit fructus lycii Aqueous extracts.
The preparation method of sea-buckthorn Aqueous extracts:Precision weighs the fresh sea-buckthorns of 10g, 200mL deionized waters is added, in 60 DEG C of water 2h is extracted in bath, has extracted and extracting solution 3000r/mim is centrifuged into 5min, and supernatant reduction vaporization is concentrated into 2g/mL to get sand Spine Aqueous extracts.
Licorice water extract preparation method:Licorice piece 10g is weighed, be soaked in water 30min, heating and refluxing extraction 1h, filtering, Supernatant is concentrated under reduced pressure into 1.5g/mL to get licorice water extract.
Concentration in the present invention after extract concentration is calculated by the following formula:
Quality (g)/volume (mL) of concentration (g/mL)=concentrate.
Concentration of the present invention measures at room temperature.
In order to test the whitening anti-aging effect of Essence of the present invention, choose the dry skin of areal, Oily, Each 40 people of neutral skin volunteer, being divided into four groups, (every group respectively includes 10 dry skins, 10 neutral skins, 10 oiliness Skin tries out volunteer), utility efficiency experiment has been carried out to A, B, C, D product respectively:
1. test period:28 days
2. Evaluation product:
A products are the Essences prepared with the embodiment of the present invention 1.
B products are the Essences that the preparation of sea-buckthorn extracting solution is not added with the embodiment of the present invention 1, the weight of sea-buckthorn extracting solution point by Black fruit fructus lycii extracting solution:Licorice extract=2:1 replaces, and other compositions are identical as A.
C products are the Essences that the preparation of black fruit fructus lycii extracting solution is not added with the embodiment of the present invention 1, black fruit fructus lycii extracting solution Weight point is by sea-buckthorn extracting solution:Licorice extract=2:1 replaces, and other compositions are identical as A.
D products are the Essences that licorice extract preparation is not added with the embodiment of the present invention 1, the weight of licorice extract point by Black fruit fructus lycii extracting solution:Sea-buckthorn extracting solution=1:1 replaces, and other compositions are identical as A.
3. test method:After each group tries out volunteer's cleaning face, A, B, C, D product are spread on into facial 15min respectively, often It is primary, using 28 days, observes and investigates trial effect;
4. it is as follows to test effect statistics:
2 A product service conditions of table are fed back
3 B product service conditions of table are fed back
4 C product service conditions of table are fed back
5 D product service conditions of table are fed back
5. feeding back conclusion:
(1) using no after four kinds of products the allergic phenomenas such as red and swollen, husking occur for volunteer, illustrate above-mentioned Essence peace Full property is good.Essence of the present invention can inhibit the formation of harmful free radicals and melanin, nutrition be injected for skin, so as to nti-freckle Whitening, anti-aging, replenishing water and preserving moisture make skin gloss high resilience, and the young state of health is presented.
(2) first groups of triers indicate that A product whitening anti-aging moistening effects are fine, and skin quality is bright after a week for continuous use Aobvious to improve, microgroove is reduced, and skin restores elastic and glossy.Second group of trier indicates that B products have certain wrinkle resistant moisturizing effect Fruit, facial lines are reduced, but whitening effect unobvious, and most triers improve unobvious using rear skin lightening degree. Third group trier indicates that C products have certain skin whitening, moisturizing effect, but goes wrinkle effect unobvious, uses front and back facial lines It has no and significantly reduces.4th group of trier indicates that D products have certain skin whitening, moisturizing effect and go wrinkle effect, but not as good as A groups are imitated Fruit is apparent.
(3) Essence of the present invention is good to the skin effect of various skin quality, this makes the target user of the present invention more Comprehensively.
In conclusion with use black fruit fructus lycii, sea-buckthorn, Radix Glycyrrhizae the group of compatibility two-by-two compared with, the present invention is by black fruit fructus lycii, sand Spine and Radix Glycyrrhizae are added in combination in Essence, and beauty functions greatly improve, and illustrate the present invention by black fruit fructus lycii, sea-buckthorn and Radix Glycyrrhizae compatibility Using having played synergistic function;Meanwhile the Essence is mildly non-stimulated, does not generate side effect, and to the shield of various skin quality Skin function well, has a vast market foreground.

Claims (16)

1. a kind of black fruit fructus lycii combines Essence, it is characterised in that:It is configured by the raw material of following parts by weight:
10~25 parts of black fruit fructus lycii Aqueous extracts, 10~16 parts of sea-buckthorn Aqueous extracts, 5~10 parts of licorice water extract, hyaluronic acid 8~12 Part, 8~12 parts of glycerine, 5~10 parts of polyethylene glycol PEG-400,3~5 parts of elastin hydrolysis, 3 ~ 6 parts of vitamin E, go from 10 ~ 25 parts of sub- water.
2. Essence according to claim 1, it is characterised in that:Its Essence by following parts by weight raw material configuration and At:
10 parts of black fruit fructus lycii Aqueous extracts, 10 parts of sea-buckthorn Aqueous extracts, 5 parts of licorice water extract, 8 parts of hyaluronic acid, 8 parts of glycerine, poly- second 5 parts of glycol PEG-400,3 parts of elastin hydrolysis, 3 parts of vitamin E, 10 parts of deionized water.
3. Essence according to claim 1 or 2, it is characterised in that:The black fruit fructus lycii Aqueous extracts are made by the following method It is standby to obtain:
Fresh black fruit fructus lycii is taken, appropriate antioxidant, grinding or crushing is added;Be added deionized water be uniformly mixed, filtering or from The heart, this step carry out 1 ~ 3 time, merge supernatant, are concentrated under reduced pressure into 1.5 ~ 2.2g/mL to get black fruit fructus lycii Aqueous extracts.
4. Essence according to claim 3, it is characterised in that:It is concentrated under reduced pressure into 2g/mL.
5. Essence according to claim 3, it is characterised in that:The antioxidant be selected from vitamin C, glutathione, The composition of one or more of lipoic acid, uric acid.
6. Essence according to claim 5, it is characterised in that:The antioxidant is selected from vitamin C.
7. Essence according to claim 6, it is characterised in that:Ascorbic dosage is fresh black fruit fructus lycii weight 10%~50%w/w。
8. Essence according to claim 7, it is characterised in that:Ascorbic dosage is fresh black fruit fructus lycii weight 40%w/w。
9. Essence according to claim 1 or 2, it is characterised in that:The sea-buckthorn Aqueous extracts are prepared by the following method It arrives:
Fresh sea-buckthorn is taken, the extraction of deionization water temperature is added to take, extracting solution filtering or centrifugation, supernatant are concentrated under reduced pressure into 1.5 ~ 2.2g/ ML is to get sea-buckthorn Aqueous extracts.
10. Essence according to claim 9, it is characterised in that:Supernatant is concentrated under reduced pressure into 2g/mL.
11. Essence according to claim 9, it is characterised in that:The temperature that temperature extraction takes is 50 ~ 70 DEG C.
12. Essence according to claim 11, it is characterised in that:The temperature that temperature extraction takes is 55 ~ 65 DEG C.
13. Essence according to claim 11, it is characterised in that:The temperature that temperature extraction takes is 60 ± 2 DEG C.
14. Essence according to claim 1 or 2, it is characterised in that:The licorice water extract is prepared by the following method It arrives:Extracting liquorice medicine materical crude slice, adds water to cook extraction, and filtering or centrifugation, supernatant are concentrated under reduced pressure into 1.0 ~ 2.0g/mL to get liquorice beverage Extract.
15. Essence according to claim 14, it is characterised in that:Supernatant is concentrated under reduced pressure into 1.5g/mL.
16. Essence described in claim 1 ~ 15 any one is preparing the skin care item with whitening and anti-aging or moisture-keeping efficacy In purposes.
CN201510759927.8A 2015-11-10 2015-11-10 A kind of black fruit fructus lycii combination Essence and application thereof Active CN105232401B (en)

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Publication number Priority date Publication date Assignee Title
CN106361629A (en) * 2016-08-31 2017-02-01 青海新泰行生物科技有限公司 Cosmetic composition containing lycium ruthenicum extract and essence
CN106377452A (en) * 2016-08-31 2017-02-08 青海新泰行生物科技有限公司 Cosmetic composition and spray containing lycium ruthenicum extract product
CN106420443B (en) * 2016-08-31 2019-05-14 青海新泰行生物科技有限公司 A kind of cosmetic composition and facial mask containing black fruit fructus lycii extract
CN106924110A (en) * 2017-02-15 2017-07-07 广东华夏友美生物科技有限公司 A kind of preparation of Ganodenna Lucidum P.E and its application process

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1195489C (en) * 1999-01-12 2005-04-06 内蒙古宇航人化妆品有限责任公司 Seabuckthorn essence concentrate
CN103565728B (en) * 2013-11-06 2015-09-30 中国科学院西北高原生物研究所 A kind of black Fructus Lycii whitening skin and preserving moisture toner/smoothing toner and preparation method thereof
CN103565699B (en) * 2013-11-06 2015-09-30 中国科学院西北高原生物研究所 A kind of black Fructus Lycii freckle removing and whitening defying age essence and preparation method thereof
CN104434741A (en) * 2014-12-23 2015-03-25 吴辰 Black wolfberry facial mask

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