CN105310934B - A kind of black fruit fructus lycii combination facial mask and application thereof - Google Patents
A kind of black fruit fructus lycii combination facial mask and application thereof Download PDFInfo
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- CN105310934B CN105310934B CN201510759872.0A CN201510759872A CN105310934B CN 105310934 B CN105310934 B CN 105310934B CN 201510759872 A CN201510759872 A CN 201510759872A CN 105310934 B CN105310934 B CN 105310934B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8129—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal or ketal radical; Compositions of hydrolysed polymers or esters of unsaturated alcohols with saturated carboxylic acids; Compositions of derivatives of such polymers, e.g. polyvinylmethylether
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/007—Preparations for dry skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/30—Characterized by the absence of a particular group of ingredients
- A61K2800/34—Free of silicones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
- A61K2800/522—Antioxidants; Radical scavengers
Abstract
The present invention provides a kind of black fruit fructus lyciis to combine facial mask, and facial mask essence forms made of it is configured by face paper and following raw material：10~25 parts of black fruit fructus lycii Aqueous extracts, 10~16 parts of sea-buckthorn Aqueous extracts, 5~10 parts of licorice water extract, 8~12 parts of hyaluronic acid, 8~12 parts of glycerine, 4005~10 parts of polyethylene glycol PEG, 3~5 parts of elastin hydrolysis, 10~25 parts of deionized water.Black fruit fructus lycii, sea-buckthorn and Radix Glycyrrhizae are added in combination in facial mask essence by the present invention, with use black fruit fructus lycii, sea-buckthorn, Radix Glycyrrhizae the group of compatibility two-by-two compared with, the beauty functions that the present invention combines facial mask greatly improve, and illustrate that black fruit fructus lycii, sea-buckthorn and Radix Glycyrrhizae compatible use have been played synergistic function by the present invention；Meanwhile the facial mask is mildly non-stimulated, does not generate side effect, and splendid to the skin care effect of dry skin, has good market prospects.
Description
Technical field
The present invention relates to a kind of black fruit fructus lyciis to combine facial mask and application thereof.
Background technology
Presently commercially available facial mask is dazzling, is divided into whitening, moisturizing, cleaning, Sage Extract, anti-ageing according to different efficacies
Always, it releives, the facial mask that compacts etc., lead, mercury, benzene in most products, phenol content are exceeded, although temporarily skin can be made to present
Glossy soft state, but it is used for a long time that cuticula can be made to fall off is thinning, lead to red swelling of the skin, forms color spot, be unfavorable for skin
Health.
Black fruit fructus lycii and sea-buckthorn are distributed across the characteristic berry in northwest China area, they are grown in salinization wasteland, salinization
In the salination ambient soil such as sand ground, growth conditions is arduous, and vitality is extremely strong, drought-enduring, the cold-resistant, high temperature resistant of energy, very precious.It is black
Fruit Chinese wolfberry fruit is rich in anthocyanidin, being capable of anti-aging, beautifying face and moistering lotion.Vitamin C content is high in sea buckthorn fruit, skin can be made to be full of
Vigor.Two kinds of berries all can be used as skin care item, also edible.
It is combined currently on the market still without using black fruit fructus lycii and sea-buckthorn, the facial mask for being used as main skin care ingredient occurs.
Invention content
In order to increase the added value of product of black fruit fructus lycii, sea-buckthorn, the present invention plans the two and is applied in combination to prepare skin care item,
However, only whether both above-mentioned combination can reach good skin care effect, someone's research yet there are no.Before inventor
Phase experiment is found, if only by the compatible use of both black fruit fructus lycii and sea-buckthorn, although also there is certain skin care effect, in different skins
Show different in matter, especially not ideal enough to the whitening and anti-aging of dry skin and other effects, target user's range is relatively narrow.For
This, inventor passes through a large amount of experiment screening, final to confirm, only on the basis of black fruit fructus lycii, sea-buckthorn, add Radix Glycyrrhizae into
Row compatibility can play the skin care effect of each raw material to the maximum extent in the case of minimum raw material type.
For these reasons, the present invention is practical provides a kind of black fruit fructus lycii combination facial mask, it is by face paper and as follows
Facial mask essence forms made of raw material configuration：
10~25 parts of black fruit fructus lycii Aqueous extracts, 10~16 parts of sea-buckthorn Aqueous extracts, 5~10 parts of licorice water extract, hyaluronic acid 8
~12 parts, 8~12 parts of glycerine, polyethylene glycol PEG-4005~10 part, 3~5 parts of elastin hydrolysis, deionized water 10~25
Part.
In a specific implementation mode of the invention, facial mask essence used is configured by the raw material of following parts by weight：
10 parts of black fruit fructus lycii Aqueous extracts, 10 parts of sea-buckthorn Aqueous extracts, 5 parts of licorice water extract, 8 parts of hyaluronic acid, 8 parts of glycerine,
PEG-4005 parts of polyethylene glycol, 3 parts of elastin hydrolysis, 10 parts of deionized water.
Wherein, the black fruit fructus lycii Aqueous extracts are prepared by the following method：
Fresh black fruit fructus lycii is taken, appropriate antioxidant, grinding or crushing is added；Deionized water is added to be uniformly mixed, filtering
Or centrifugation, this step carry out 1~3 time, merge supernatant, are concentrated under reduced pressure into 1.5~2.2g/mL, preferably 2g/mL is to get black
Fruit matrimony vine Aqueous extracts.
Wherein, the use of antioxidant is to protect the anthocyanidin isoreactivity ingredient in black fruit fructus lycii, and antioxidant can
To select the composition of one or more of vitamin C, glutathione, lipoic acid or uric acid.
In a specific implementation mode of the invention, antioxidant selects vitamin C；Further, ascorbic dosage is
10%~50%w/w of fresh black fruit fructus lycii weight, preferably 40%w/w.
Wherein, the sea-buckthorn Aqueous extracts are prepared by the following method：
Fresh sea-buckthorn is taken, the extraction of deionization water temperature is added to take, extracting solution filtering or centrifugation, supernatant are concentrated under reduced pressure into 1.5
~2.2g/mL, preferably 2g/mL are to get sea-buckthorn Aqueous extracts.
Wherein, the temperature that temperature extraction takes is 50~70 DEG C, is further 55~65 DEG C, a specific implementation mode of the invention
It is middle to select temperature for 60 ± 2 DEG C.
Wherein, the licorice water extract is prepared by the following method：Extracting liquorice medicine materical crude slice, adds water to cook extraction, filtering or
Centrifugation, supernatant are concentrated under reduced pressure into 1.0~2.0g/mL, and preferably 1.5g/mL is to get licorice water extract.
The present invention also provides the preparation methods of above-mentioned facial mask, it includes following operating procedure：
(1) take facial mask essence raw material by weight ratio, by after raw material mixing to get facial mask essence；
(2) face paper is taken, after being impregnated in facial mask essence, takes out packaging.
The present invention also provides a kind of facial mask essences, it is configured by the raw material of following parts by weight：
10~25 parts of black fruit fructus lycii Aqueous extracts, 10~16 parts of sea-buckthorn Aqueous extracts, 5~10 parts of licorice water extract, hyaluronic acid 8
~12 parts, 8~12 parts of glycerine, polyethylene glycol PEG-4005~10 part, 3~5 parts of elastin hydrolysis, deionized water 10~25
Part.
The present invention also provides use of the above-mentioned facial mask in preparing the skin care item with whitening and anti-aging or moisture-keeping efficacy
On the way.
The present invention the study found that the skin care item have good skin effect for dryness, neutrality or Oily, but
It is that, if compared with the facial mask of other material combinations, product of the present invention is even more ideal to the skin care effect of dry skin, more suitable for
The use of dry skin.
Black fruit fructus lycii, sea-buckthorn and Radix Glycyrrhizae are added in combination in facial mask essence by the present invention, with use black fruit fructus lycii, sea-buckthorn,
The group of compatibility two-by-two of Radix Glycyrrhizae is compared, and the beauty functions that the present invention combines facial mask greatly improve, and illustrates the present invention by black fruit fructus lycii, sand
Spine and Radix Glycyrrhizae compatible use have played synergistic function；Meanwhile the facial mask is mildly non-stimulated, does not generate side effect, and to dry
Property skin skin care effect it is splendid, have good market prospects.
Heretofore described face paper can select standard compliant general face paper on the market, also not have to its material
It is restricted, can be silk, cotton, terylene, blended, tencel, biological fiber etc..
Specific implementation mode
Specific embodiments of the present invention are described in detail below：
1 each embodiment Essence of table matches
Preparation method：Essence is uniformly mixed, is sterilized, then face paper is impregnated 20~25 minutes in Essence, most
Vacuum Package is to get facial mask of the present invention afterwards.
In the present invention, black fruit fructus lycii Aqueous extracts are to prepare in the following manner：The fresh black fruit fructus lyciis of 10g accurately are weighed,
To keep the stability of anthocyanidin in black fruit fructus lycii, addition 4g vitamin Cs are broken with mortar grinder, obtain black fruit fructus lycii pulp,
100mL deionized waters are added to stir evenly, filter, residue adds 100mL deionized waters again, filters, and merges supernatant twice, decompression
2g/mL is concentrated into get black fruit fructus lycii Aqueous extracts.
The preparation method of sea-buckthorn Aqueous extracts：Precision weighs the fresh sea-buckthorns of 10g, 200mL deionized waters is added, in 60 DEG C of water
2h is extracted in bath, has extracted and extracting solution 3000r/mim is centrifuged into 5min, and supernatant reduction vaporization is concentrated into 2g/mL to get sand
Spine Aqueous extracts.
Licorice water extract preparation method：Licorice piece 10g is weighed, be soaked in water 30min, heating and refluxing extraction 1h, filtering,
Supernatant is concentrated under reduced pressure into 1.5g/mL to get licorice water extract.
Concentration in the present invention after extract concentration is calculated by the following formula：
Quality (g)/volume (mL) of concentration (g/mL)=concentrate.
Concentration of the present invention measures at room temperature.
In order to verify whether product of the present invention meets hygienic practice, the sample prepared by Examples 1 to 4 is sent to third party
Testing agency, detection product whether meet corresponding hygienic practice, third party testing agency by being detected to indices,
The result shows that meeting corresponding specification, finally judge that the sample prepared by Examples 1 to 4 meets《Facial mask》(QB/T2872-
2007) limitation requirement.
In order to test the whitening anti-aging effect of facial mask of the present invention, choose the dry skin of areal, Oily, in
Property each 40 people of skin volunteer, being divided into four groups, (every group respectively includes 10 dry skins, 10 neutral skins, 10 oiliness skins
Skin tries out volunteer), utility efficiency experiment has been carried out to A, B, C, D product respectively：
1. test period：28 days
2. Evaluation product：
A products are the black fruit fructus lycii sea-buckthorn facial masks prepared with the embodiment of the present invention 1.
B products are the facial masks that the preparation of sea-buckthorn extracting solution is not added with the embodiment of the present invention 1, and the weight point of sea-buckthorn extracting solution is by black
Fruit fructus lycii extracted solution：Licorice extract=2：1 replaces, and other compositions are identical as A.
C products are the facial mask that the preparation of black fruit fructus lycii extracting solution is not added with the embodiment of the present invention 1, the weight of black fruit fructus lycii extracting solution
Amount point is by sea-buckthorn extracting solution：Licorice extract=2：1 replaces, and other compositions are identical as A.
D products are the facial masks that licorice extract preparation is not added with the embodiment of the present invention 1, and the weight point of licorice extract is by black
Fruit fructus lycii extracted solution：Sea-buckthorn extracting solution=1：1 replaces, and other compositions are identical as A.
3. test method：After each group tries out volunteer's cleaning face, A, B, C, D product are spread on into facial 15min respectively, often
It is primary, using 28 days, observes and investigates trial effect；
4. it is as follows to test effect statistics：
2 A product service conditions of table are fed back
3 B product service conditions of table are fed back
4 C product service conditions of table are fed back
5 D product service conditions of table are fed back
5. feeding back conclusion：
(1) using no after four kinds of products the allergic phenomenas such as red and swollen, husking occur for volunteer, illustrate above-mentioned facial mask safety
Property is good.
(2) first groups of triers indicate that A product whitening anti-aging moistening effects are fine, and skin quality is bright after a week for continuous use
Aobvious to improve, microgroove is reduced, and skin restores elastic and glossy.Second group of trier indicates that B products have certain wrinkle resistant moisturizing effect
Fruit, facial lines are reduced, but whitening effect unobvious, and most triers improve unobvious using rear skin lightening degree.
Third group trier indicates that C products have certain skin whitening, moisturizing effect, but goes wrinkle effect unobvious, uses front and back facial lines
It has no and significantly reduces.4th group of trier indicates that D products have certain skin whitening, moisturizing effect and go wrinkle effect, but not as good as A groups are imitated
Fruit is apparent.
By first group and other three groups relatively from the point of view of, for the skin care effect of dry skin volunteer, the effect of A products is bright
It is aobvious more preferable, illustrate A products compared with other 3 kinds of compatibility products more suitable for dry skin, this makes the target user of the present invention more
Comprehensively.
In conclusion with use black fruit fructus lycii, sea-buckthorn, Radix Glycyrrhizae the group of compatibility two-by-two compared with, the present invention is by black fruit fructus lycii, sand
Spine and Radix Glycyrrhizae are added in combination in facial mask essence, and the beauty functions for combining facial mask greatly improve, illustrate the present invention by black fruit fructus lycii,
Sea-buckthorn and Radix Glycyrrhizae compatible use have played synergistic function；Meanwhile the facial mask is mildly non-stimulated, does not generate side effect, and right
The skin care effect of dry skin is splendid, has good market prospects.
Claims (17)
1. a kind of black fruit fructus lycii combines facial mask, it is characterised in that：It is made of face paper and the configuration of following raw material
Facial mask essence forms：
10~25 parts of black fruit fructus lycii Aqueous extracts, 10~16 parts of sea-buckthorn Aqueous extracts, 5~10 parts of licorice water extract, hyaluronic acid 8~12
Part, 8~12 parts of glycerine, 5~10 parts of polyethylene glycol PEG-400,3~5 parts of elastin hydrolysis, 10~25 parts of deionized water.
2. facial mask according to claim 1, it is characterised in that：Its facial mask essence by following parts by weight raw material configuration and
At：
10 parts of black fruit fructus lycii Aqueous extracts, 10 parts of sea-buckthorn Aqueous extracts, 5 parts of licorice water extract, 8 parts of hyaluronic acid, 8 parts of glycerine, poly- second
5 parts of glycol PEG-400,3 parts of elastin hydrolysis, 10 parts of deionized water.
3. facial mask according to claim 1 or 2, it is characterised in that：The black fruit fructus lycii Aqueous extracts are prepared by the following method
It obtains：
Fresh black fruit fructus lycii is taken, appropriate antioxidant, grinding or crushing is added；Be added deionized water be uniformly mixed, filtering or from
The heart, this step carry out 1~3 time, merge supernatant, are concentrated under reduced pressure into 1.5~2.2 g/mL to get black fruit fructus lycii Aqueous extracts.
4. facial mask according to claim 3, it is characterised in that：It is concentrated under reduced pressure into 2g/mL.
5. facial mask according to claim 3, it is characterised in that：The antioxidant is selected from vitamin C, glutathione, sulphur
The composition of one or more of octanoic acid, uric acid.
6. facial mask according to claim 5, it is characterised in that：The antioxidant is selected from vitamin C.
7. facial mask according to claim 6, it is characterised in that：Ascorbic dosage is the 10% of fresh black fruit fructus lycii weight
~50%w/w。
8. facial mask according to claim 6, it is characterised in that：Ascorbic dosage is the 40% of fresh black fruit fructus lycii weight
w/w。
9. facial mask according to claim 1 or 2, it is characterised in that：The sea-buckthorn Aqueous extracts are prepared by the following method：
Fresh sea-buckthorn is taken, the extraction of deionization water temperature is added to take, extracting solution filtering or centrifugation, supernatant are concentrated under reduced pressure into 1.5 ~ 2.2g/
ML is to get sea-buckthorn Aqueous extracts.
10. facial mask according to claim 9, it is characterised in that：Supernatant is concentrated under reduced pressure into 2g/mL.
11. facial mask according to claim 9, it is characterised in that：The temperature that temperature extraction takes is 50 ~ 70 DEG C.
12. facial mask according to claim 11, it is characterised in that：The temperature that temperature extraction takes is 55 ~ 65 DEG C.
13. facial mask according to claim 11, it is characterised in that：The temperature that temperature extraction takes is 60 ± 2 DEG C.
14. facial mask according to claim 1 or 2, it is characterised in that：The licorice water extract is prepared by the following method
It arrives：Extracting liquorice medicine materical crude slice, adds water to cook extraction, and filtering or centrifugation, supernatant are concentrated under reduced pressure into 1.0 ~ 2.0g/mL to get liquorice beverage
Extract.
15. facial mask according to claim 14, it is characterised in that：Supernatant is concentrated under reduced pressure into 1.5g/mL.
16. facial mask described in claim 1 ~ 8 any one is in preparing the skin care item with whitening and anti-aging or moisture-keeping efficacy
Purposes.
17. purposes according to claim 16, it is characterised in that：The skin care item are the skin cares that dry skin crowd uses
Product.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510759872.0A CN105310934B (en) | 2015-11-10 | 2015-11-10 | A kind of black fruit fructus lycii combination facial mask and application thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510759872.0A CN105310934B (en) | 2015-11-10 | 2015-11-10 | A kind of black fruit fructus lycii combination facial mask and application thereof |
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|---|---|
| CN105310934A CN105310934A (en) | 2016-02-10 |
| CN105310934B true CN105310934B (en) | 2018-09-21 |
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Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105832616A (en) * | 2016-05-20 | 2016-08-10 | 郑凯峰 | Thermal spring intensive moisturizing and skin-tendering mask and preparation method thereof |
| CN107224417B (en) * | 2017-07-04 | 2021-05-04 | 李湘宁 | Chlorella facial mask and preparation method and application thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1799533A (en) * | 2005-01-07 | 2006-07-12 | 张善领 | Spot-removing and whitening essence liquid |
| CN103565699A (en) * | 2013-11-06 | 2014-02-12 | 中国科学院西北高原生物研究所 | Lycium ruthenicum mill freckle-removing and whitening anti-aging essence and preparation method of essence |
| CN104434741A (en) * | 2014-12-23 | 2015-03-25 | 吴辰 | Black wolfberry facial mask |
-
2015
- 2015-11-10 CN CN201510759872.0A patent/CN105310934B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1799533A (en) * | 2005-01-07 | 2006-07-12 | 张善领 | Spot-removing and whitening essence liquid |
| CN103565699A (en) * | 2013-11-06 | 2014-02-12 | 中国科学院西北高原生物研究所 | Lycium ruthenicum mill freckle-removing and whitening anti-aging essence and preparation method of essence |
| CN104434741A (en) * | 2014-12-23 | 2015-03-25 | 吴辰 | Black wolfberry facial mask |
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|---|---|
| CN105310934A (en) | 2016-02-10 |
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