CN108113932A - Ms's anticreep shampoo - Google Patents

Abstract

The present invention relates to one kind to educate hair class special cosmetics, and in particular to a kind of Ms's anticreep shampoo includes the raw material of following mass component：Water, laureth sulfuric ester ammonium, bay alcohol sulfuric ester ammonium, sodium lauroyl sarcosine, Cocoamidopropyl betaine, glycol distearate, guar hydroxypropyltrimonium chloride, sodium chloride, hydrolyzed wheat protein, essence, panthenol, cetostearyl alcohol, citric acid, EDETATE SODIUM, methyl hydroxybenzoate, methylisothiazolinone, the agent of hair anticreep, antioxidant.Ms's anticreep shampoo of the present invention; using natural plant formula; contain the ingredients such as Cacumen Platycladi extract, fleece-flower root root extract, Fructus Viticis extract, gadol extract and Black Ganoderma extract; cleanable scalp dirt, correct leatherware have preferable bacteriostasis, nutrition scalp; contribute to the growing environment of improvement hair; the toughness of hair is improved, reduces alopecia, disconnected hair, there is protective effect to the hair of damage.

Description

Ms's anticreep shampoo

Technical field

The invention belongs to washing product fields, and in particular to a kind of Ms's anticreep shampoo.

Background technology

Present people’s lives pressure is increasing, and alopecia has no longer been the disease of the elderly Chang get, and young man also faces Alopecia, alopecia areata or even the danger for letting out top.Many people receive puzzlement due to alopecia, and there are many reason for causing alopecia, cause alopecia Factor may be to lack protein or vitamin isoreactivity substance in vivo, the missing of these nutritional ingredients interferes the strong of hair Kang Shengchang, it is popular in recent years to the contaminating of hair, scald, roll up, these can also damage hair, and hair can be made to become more and more rare. Existing anti-hair loss products mainly add the chemicals with hair follicle stimulating effect of deoiling, and can clear up scalp in a short time, stimulate Hair follicle hair tonic, but long-time service can play reaction, and the shampoo of some pure Chinese medicine galenicals, hair growth accelerating act on but It is not obvious.Application for a patent for invention CN 106606458 discloses a kind of anticreep strengthen the hair nutrition hair-washing water, the anticreep strengthen the hair battalion Shampoo is supported to be prepared by following raw materials：Dodecyl polyoxyethylene ether sodium sulphate, cocinic acid diethanol phthalein amine, small particle Silicone emulsion, Wu Sima grass, fennelflower seed, the fleece-flower root, ginger, Qamgur you and deionized water, the invention use pure natural plant Object extract, and shampoo reduces chemical addition agent dosage in the invention, can effective hair growing, prevent epilation, pierce Swash head blood circulation, activate hair follicle, nutrition scalp.

The content of the invention

The technical problems to be solved by the invention are to provide a kind of Ms's anticreep shampoo.

A kind of Ms's anticreep shampoo includes the raw material of following mass component：Water, laureth sulfuric ester ammonium, bay Alcohol sulfuric ester ammonium, sodium lauroyl sarcosine, Cocoamidopropyl betaine, glycol distearate, melon glue hydroxypropyl three Ammonio methacrylate, sodium chloride, hydrolyzed wheat protein, essence, panthenol, cetostearyl alcohol, citric acid, EDETATE SODIUM, methyl hydroxybenzoate, Methylisothiazolinone, hair anticreep agent.

Preferably, a kind of Ms's anticreep shampoo includes the raw material of following mass component：Water, laureth sulfuric ester Ammonium, bay alcohol sulfuric ester ammonium, sodium lauroyl sarcosine, Cocoamidopropyl betaine, glycol distearate, melon glue hydroxyl Hydroxypropyltrimonium chloride, sodium chloride, hydrolyzed wheat protein, essence, panthenol, cetostearyl alcohol, citric acid, EDETATE SODIUM, hydroxyl Benzene methyl, methylisothiazolinone, the agent of hair anticreep, antioxidant.

Specifically, a kind of Ms's anticreep shampoo, is made of the raw material of following components by weight percent：Laureth sulfuric ester ammonium 4-10wt%, bay alcohol sulfuric ester ammonium 4-10wt%, sodium lauroyl sarcosine 1-4wt%, Cocoamidopropyl betaine 0.5- 2.5wt%, glycol distearate 0.4-2wt%, guar hydroxypropyltrimonium chloride 0.5-1.5wt%, sodium chloride 0.3-1.2wt%, hydrolyzed wheat protein 0.2-0.8wt%, essence 0.2-0.6wt%, panthenol 0.2-0.4wt%, cetearyl alcohol Alcohol 0.2-0.4wt%, citric acid 0.05-0.25wt%, EDETATE SODIUM 0.02-0.18wt%, methyl hydroxybenzoate 0.05- 0.12wt%, methylisothiazolinone 0.005-0.01wt%, hair anticreep agent 1-5wt%, antioxidant 0.5-1.5wt%, Surplus is water.

The hair anticreep agent is Cacumen Platycladi extract, fleece-flower root root extract, one kind in Fructus Viticis extract or more Kind.

Fructus viticis, Chinese medicine name.Alias：Wild pepper reality, Jing Zi, FRUCTUS VITICIS, turnip, wild pepper, white back fungus, small sword bean rattan, White leeward, white back of the body grass.Source is Verbenaceae Vitex rotundifolia or the dry mature fruit of wild pepper.Main product in Shandong, Jiangxi, The provinces such as Zhejiang, Fujian.Acrid flavour, hardship, cold nature.Return lung, bladder, Liver Channel.Its primary efficacy is dispelling wind and heat from the body, and head clearing removes Wet place joint.It is usually used in exogenous headache, polarization intermittent headache, the mesh that swoons is dark, many tear of red eyes, and pain, gingivitis, arthritis with fixed pain caused by dampness are arrested in mesh eyeball Contraction.

The antioxidant is gadol extract and/or Black Ganoderma extract.

The Cacumen Platycladi extract is prepared by the following method to obtain：Arbor-vitae leaf raw material is taken, cleans and is added to the water after drying It decocts 2-4 times, each decocting time is 45-160min, and the quality of each decoction plus water is 8-10 times of arbor-vitae leaf raw material, then By being concentrated under reduced pressure, being dried to obtain Cacumen Platycladi extract.

The fleece-flower root root extract why Polygonum Multiflorum root impalpable powder and/or fleece-flower root root enzymatic hydrolyzed extract.

The preparation process of the fleece-flower root root impalpable powder is：After fleece-flower root root is taken to clean, 20-40 mesh is crushed to, is then put It is superfine to obtain the fleece-flower root root that Average Particle Diameters are 8-14 μm by the ultramicro grinding 20-70min under conditions of subzero 5-20 DEG C Powder.

The preparation method of the fleece-flower root root enzymatic hydrolyzed extract comprises the following steps：

I, is weighed to dry after fleece-flower root root is cleaned and crushed, and the water of 1-4 times of quality is added in into fleece-flower root root powder, 10-20min is stirred with 150-350r/min rotating speeds at a temperature of 25-35 DEG C, obtains fleece-flower root root powder suspension；

The above-mentioned fleece-flower root root powder suspension homogeneous 4-9min, homogenization pressure 100-110MPa are obtained the fleece-flower root by II, Mixed liquor then adds in the complex enzyme agent of 0.2-0.5% fleece-flower root root mixed liquor quality in the fleece-flower root mixed liquor after homogeneous, It is 1 in mass ratio by neutral proteinase and cellulase that wherein complex enzyme agent, which is,：(1-3) is mixed, then is with concentration 0.5mo1/L acetums adjust pH to 4.0-5.0, are then placed into drying box the sealing enzymolysis 60- at 35-45 DEG C 80min obtains enzymolysis liquid；

Above-mentioned enzymolysis liquid is separated by filtration by III, is removed filter residue, is carried out under conditions of then acquired solution is placed in 20-30 DEG C Ultrafiltration collects filtrate, obtains the filtrate after ultrafiltration；

IV, is by the filtrate after above-mentioned ultrafiltration and absolute ethyl alcohol by volume 1:(1-3) is mixed, then in ultrasonic power Ultrasonic extraction 10-30min under the conditions of 400-600W, 35-55 DEG C, then at 360-600W Microwave Extraction 5-15min, after the completion of alcohol extracting Mixed liquor at 40-60 DEG C of temperature is rotated into 1-3h, recycles absolute ethyl alcohol, concentration is until mixeding liquid volume becomes former mixing liquid Long-pending 1/8-1/6, obtains concentrate；

V, by above-mentioned concentrate in subzero 40 DEG C-it is 30 DEG C subzero at a temperature of be freeze-dried 30-40min, be then ground to Powder simultaneously crosses 150-250 mesh standard sieves to get fleece-flower root root enzymatic hydrolyzed extract.

The Fructus Viticis extract is prepared by the following method to obtain：By fresh fructus viticis natural air drying, 20-60 is crushed to Mesh, by 1:(20-80) weight ratio adds in boiling water and carries out 3 decoctions, and decocting time 30-70min decocts hydration simultaneously every time, decompression It concentrates as 40-70 times of wild pepper protonatomic mass, adds in the absolute ethyl alcohol of 1-3 times of quality, 4-8h, centrifugation removal are refrigerated at 2-8 DEG C Precipitation, is then recovered under reduced pressure ethyl alcohol, is concentrated into no alcohol taste, is dried at 50-90 DEG C to constant weight, obtains Fructus Viticis extract.

The gadol extract is prepared by the following method to obtain：Rhodiola root raw material is taken, cleans and adds in 50- after drying 80wt% alcohol refluxs extract 1-3 times, and extraction time 65-85min, each Extracting temperature is 40-60 DEG C, every time during extraction The rate of charge of rhodiola root raw material and ethyl alcohol is 1：(5-12) (g/ml) is filtered after the completion of extraction, is then combined with extracting solution, and decompression is dense It is dried after contracting to constant weight, obtains gadol extract.

The preparation method of the Black Ganoderma extract comprises the following steps：

I, is dried after Black Ganoderma fructification is cut into slices, and is then crushed to 30-60 mesh, is obtained Black Ganoderma powder；

II, adds in the extractant of 6-14 times of quality into above-mentioned Black Ganoderma powder, and 1-3h is extracted at 90-98 DEG C, filtering Filtrate is collected, filter residue extracts again with condition, merges filtrate twice, obtains Black Ganoderma extracting solution；

Above-mentioned Black Ganoderma extracting solution is dried 2-10h by III, obtains the Black Ganoderma extract.

In the preparation method of the Black Ganoderma extract, the extractant is the one or more in ethyl alcohol, ammonium hydroxide or water； The drying mode of the Black Ganoderma extracting solution is the one or more in heated-air drying, freeze-drying and vacuum drying.

A kind of production technology of Ms's anticreep shampoo, comprises the following steps：

I, weighs each component raw material by formula；

II, by 80-90wt% water, laureth sulfuric ester ammonium, bay alcohol sulfuric ester ammonium, sodium lauroyl sarcosine, EDETATE SODIUM is added in homogenizer, homogeneous 10-20min, 80-85 DEG C of whipping temp；

III, will add in glycol distearate, cetostearyl alcohol, methyl hydroxybenzoate, keep temperature, stir 10-30min；

IV, is cooled to 65-75 DEG C, adds in Cocoamidopropyl betaine, sodium chloride, melon glue Hydroxyproyl Trimethyl chlorination Ammonium, panthenol, citric acid, stir evenly；

V, is cooled to 45-60 DEG C, adds in remaining water, the agent of hair anticreep, antioxidant, stirs evenly；

VI, is cooled to 30-40 DEG C, adds in hydrolyzed wheat protein, essence, methylisothiazolinone, stirs evenly；

VIII, is stood, defoaming and quality inspection, after quality inspection qualifications, is transported to bottling department, is carried out by specified amount filling, obtains Ms Anticreep shampoo.

The raw material described in the present invention：

Laureth sulfuric ester ammonium, No. CAS：1335-72-4 is a kind of bay 01 derivatives, often makees in cosmetics Remover, foaming agent have good foaming characteristic, are usually used in personal cleanliness's articles for use, particularly the product of low ph value, this ingredient Irritation is relatively low after ethoxylation.

Bay alcohol sulfuric ester ammonium, No. CAS：68955-19-1 belongs to strong detergent ingredient, has stronger cleaning energy Power, while there is foaming, detergent is used as in cosmetics, the foaming agent being suitable for use as in toothpaste, shampoo, hair washing Foaming and cleaning ingredients in cream, bubble bath.

Sodium lauroyl sarcosine, No. CAS：137-16-6, is a kind of foaming agent and surfactant, it is by creatine or coffee Coffee belongs to modified fat acids because of Hamposyl L salt made of decomposition.It frequently appears in shampoo, shower cream, face cleaning It is used as foaming agent, surfactant and hair conditioner in breast and Shaving Products.Sodium lauroyl sarcosine can be soft by improving Soft and glossiness promotes the perception of hair, particularly those hairs for being subject to chemical damage.The ingredient can be used for cleaning Skin and hair mix oil and spot and are easier to rinse out.It is considered as often a kind of penetration-assisting agent, thus it is possible to vary skin knot Structure helps other chemical penetrations to skin depths.

Cocoamidopropyl betaine, No. CAS：61789-40-0 is a kind of amphoteric surfactant, is had good clear It washes, blister, opsonic action, good with anion, cation and nonionic surfactant compatibility, this product irritation is small, performance Mildly, foam is fine and smooth and stablizes, and suitable for configuration shampoo, shower cream, facial cleanser etc., can enhance the flexibility to hair, skin, When this product is with appropriate anion surfactant compatibility, there is apparent thickening effect, also act as conditioner, wetting agent, sterilization Agent, antistatic agent etc., use in the present invention as detergent.

Glycol distearate, No. CAS：111-55-7 often makees emollients, emulsifier and pearling agent and uses, the ingredient It can provide product pearlescent gloss, increase product viscosity, also with skin care, anlistatig effect, with other types Surfactant compatibility it is preferable, and stablize, and the ingredient is non-stimulated to skin, in the present invention as pearling agent.

Guar hydroxypropyltrimonium chloride, No. CAS：65497-29-2 is a kind of high molecular weight water soluble polymer, is It is raw material using natural guars, is made with the reaction of dehydration contracting glycerin ether trimethyl ammonia chloride ammonia, makees antistatic agent in cosmetics It uses with film forming agent, is used in this product as conditioner for hair.

Hydrolyzed wheat protein, No. CAS：70084-87-6, containing abundant Cystine, Hydrolyzed Protein, antioxidation and Softness refinement skin, has special Safflower Oil that can help improve wrinkle, is used in this product as conditioner for hair.

Panthenol, No. CAS：81-13-0 is mainly used as moisturizer and skin conditioning agent, is used together with vitamin B6, percutaneously Skin can increase hyaluronic acid contents in skin after absorbing, promote the metabolism of human body protein, fat, carbohydrate, protect skin and stick Film prevents small wrinkle, and inflammation, solarization are not glutinous greasy moisturizing ingredients, have potent moistening effect, and with skin sebum film phase Closely, it is easy to the cuticula for absorbing infiltration and infiltration skin surface, makes skin soft, effectively prevent the coarse phenomenon of skin, reach flesh The effect of skin moisturizing and tissue repair, gives skin gloss.

Cetostearyl alcohol, No. CAS：67762-27-0 belongs to fatty alcohol, and appearance is White waxy object, can provide butyrous Quality is used frequently as emollients, emulsifier, thickener, can be artificial synthesized, can also be extracted from coconut fatty alcohol.The ingredient Product can be helped to be easier in penetrating to the skin, moreover it is possible to be used as emulsifier, make product more easy to apply, be used as in the present invention Emollient.

Citric acid, No. CAS：77-92-9, belongs to one kind of tartaric acid, and main function is to speed up cutin update, is usually used in breast Liquid, creams, shampoo, whitening articles for use, anti-aging articles for use, Acne etc..The update of cutin contributes to the middle black of skin The peeling of element, the receipts of pore are thin, dissolving of blackhead etc..It is combined with sodium acid carbonate can make foaming bath foam, they are generated Carbon dioxide, and pleasant bubble is createed, it is used in this product as pH adjusting agent.

Methyl hydroxybenzoate, No. CAS：99-76-3 for parabens preservative, is widely used in cosmetics, nipalgin The preservative of esters is stronger to the antibacterial action of yeast and mold, slightly worse to the effect of bacterium, mainly by destroying microorganism Cell membrane, make intracellular protein denaturation, and inhibit cellular respiration enzyme and transfer enzyme system activity and play antibacterial work With concentration is 0.14% when European Union's regulation propylben in 2014, butyl hydroxybenzoate and its esters are used alone, and is permitted with other Perhaps total concentration must not exceed 0.8% when the paraben esters used mix together.

Methylisothiazolinone, abbreviation MIT, No. CAS：2682-20-4 is a kind of not chloride preservative, can inhibit The growth of bacterium, fungi and mould just can effectively kill various bacteria at low concentrations, therefore extensive as efficient antiseptic For in cosmetics and personal-care supplies, ministry of Health of China to provide that its maximum acceptable concentration in cosmetics is 0.01%.

A kind of Ms's anticreep shampoo of the present invention, using natural plant formula, contains Cacumen Platycladi extract, the fleece-flower root The plant components such as root extract, Fructus Viticis extract, gadol extract and Black Ganoderma extract, cleanable scalp dirt are right Scalp has preferable bacteriostasis, while nutrition scalp, helps to improve the growing environment of hair, improves the toughness of hair, subtract Few alopecia, disconnected hair have protective effect to the hair of damage, in addition also mild non-stimulated, safe and healthy.

Specific embodiment

The foregoing invention content of the present invention is described in further detail With reference to embodiment, but should not be incited somebody to action This scope for being interpreted as the above-mentioned theme of the present invention is only limitted to following embodiments.In the present invention, if not refering in particular to, all devices It is bought from market or for industry commonly used equipment；Experimental method in embodiment is this field routine side unless otherwise instructed Method.

Disintegrating apparatus uses the 20B type pulverizers of Guangzhou Lai Ang mechanical equipments Co., Ltd production.

Spray drying device rubs (Shanghai) Electronic Science and Technology Co., Ltd. purchased from fine jade, model QIMO-8000T.

The model LWF6-BI of oscillatory type drug micronizer is provided by Jinan Long Wei pharmaceutical equipments Co., Ltd.

Ultrafiltration apparatus uses the HX type ultrafiltration systems of Heng Xin environmental protection equipments Co., Ltd of Jingjiang City manufacture.

Ultrasonic device is BK-600B type supersonic wave cleaning machines, purchased from Bakr Ultrasonic Technology (Group) Co., Ltd..

The model 101-2-BS of electric heating constant-temperature blowing drying box, purchased from Shanghai leap Medical Devices Co., Ltd.

Vacuum freeze drier is the SCIENTZ-12N type vacuum provided by NingBo XinZhi Biology Science Co., Ltd Freeze drier.

The model DZF of vacuum drying chamber, purchased from upper sea otter jump experimental instruments and equipment limited

Homogenizer uses RHG type high-shear emulsifying tanks, is provided by Wenzhou Machinery Co., Ltd. of New School.

Embodiment 1

A kind of Ms's anticreep shampoo, is made of the raw material of following components by weight percent：Laureth sulfuric ester ammonium 7wt%, Bay alcohol sulfuric ester ammonium 7wt%, sodium lauroyl sarcosine 2.5wt%, Cocoamidopropyl betaine 1.5wt%, ethylene glycol two Stearate 1.2wt%, guar hydroxypropyltrimonium chloride 1wt%, sodium chloride 0.75wt%, hydrolyzed wheat protein 0.5wt%, essence 0.4wt%, panthenol 0.3wt%, cetostearyl alcohol 0.3wt%, citric acid 0.15wt%, EDETATE SODIUM 0.1wt%, methyl hydroxybenzoate 0.06wt%, methylisothiazolinone 0.006wt%, Cacumen Platycladi extract 1wt%, fleece-flower root root carry It is water to take object 1wt%, Fructus Viticis extract 1wt%, antioxidant 1wt%, surplus.

The Cacumen Platycladi extract is prepared by the following method to obtain：Arbor-vitae leaf raw material is taken, cleans and is added to the water after drying It decocts 3 times, first time decocting time is 160min, and second of decocting time is 90min, and third time decocting time is 45min, often Secondary to decoct add the weight of water for arbor-vitae leaf raw material 10 times, it is 1.21 that relative density is then concentrated under reduced pressure at a temperature of 50 DEG C Concentrate is dried with spray drying process, and inlet air temperature and leaving air temp are respectively 160 DEG C, 70 DEG C, and obtaining cacumen biotae after dry carries Take object.

The fleece-flower root root extract why Polygonum Multiflorum root enzymatic hydrolyzed extract, the preparation side of the fleece-flower root root enzymatic hydrolyzed extract Method comprises the following steps：

I, is weighed to dry after fleece-flower root root is cleaned and crushed, and the water of 2 times of quality is added in into fleece-flower root root powder, 30 15min is stirred with 200r/min rotating speeds at a temperature of DEG C, obtains fleece-flower root root powder suspension；

Fleece-flower root root powder suspension obtained above is moved into homogenizer, homogeneous 7min by II, and homogenization pressure is 100MPa adds in the 0.3wt% complex enzyme agent of fleece-flower root root mixed liquor quality in the fleece-flower root mixed liquor after homogeneous, wherein compound It is 1 in mass ratio by neutral proteinase and cellulase that enzyme agent, which is,：2, then with concentration be 0.5mo1/L acetums adjust pH to 4.5, the sealing enzymolysis 70min at 40 DEG C is then placed in drying box；

Removal filter residue is separated by filtration after the completion of III, enzymolysis, obtains enzymolysis liquid, will be surpassed under conditions of 25 DEG C of enzymolysis liquid Filtrate is collected in filter；

Filtrate after above-mentioned ultrafiltration and absolute ethyl alcohol are 1 by volume by IV,:1 is mixed, then in ultrasonic power Then at 480W Microwave Extraction 10min, rotation is put into after the completion of alcohol extracting by 600W, ultrasonic extraction 20min under the conditions of 45 DEG C for mixed liquor Evaporator rotates 1.5h at a temperature of 50 DEG C, recycles absolute ethyl alcohol, and concentration is until mixeding liquid volume becomes former mixeding liquid volume 1/8, obtain concentrate；

Above-mentioned concentrate is freeze-dried 35min by V, at a temperature of subzero 35 DEG C, is pulverized after dry and is crossed 200 Mesh standard sieve is to get fleece-flower root root enzymatic hydrolyzed extract.

The Fructus Viticis extract is prepared by the following method to obtain：By fresh fructus viticis natural air drying, 40 mesh are crushed to, By 1:60 weight ratios add in boiling water and carry out 3 decoctions, and decocting time difference 50min decocts hydration simultaneously every time, is concentrated under reduced pressure to be climing 60 times of chaste tree protonatomic mass add in the absolute ethyl alcohol of 2 times of quality, and 6h is refrigerated at 2-8 DEG C, and centrifugation removal precipitation then depressurizes back Ethyl alcohol is received, is concentrated into no alcohol taste, is dried at a temperature of 80 DEG C to constant weight, obtains Fructus Viticis extract.

The antioxidant is gadol extract and Black Ganoderma extract, wherein gadol extract and Black Ganoderma extraction Amount of substance ratio is 1：1.

The gadol extract is prepared by the following method to obtain：Rhodiola root raw material is taken, cleans and is added in after drying 65wt% alcohol refluxs extract 3 times, extraction time 75min, and each Extracting temperature is 50 DEG C, and rhodiola root is former during extraction every time The rate of charge of material and ethyl alcohol is 1：8 (g/ml) are filtered after the completion of extraction, are then combined with extracting solution, nothing is concentrated into after being concentrated under reduced pressure Alcohol taste is dried to constant weight at a temperature of 65 DEG C, obtains gadol extract.

The preparation method of the Black Ganoderma extract comprises the following steps：

I, is put into baking oven after Black Ganoderma fructification is cut into slices and dries, and then puts into pulverizer and carries out fine crushing, powder 40 mesh are broken to, gained Black Ganoderma powder are put into the 95wt% ethanol solutions of 10 times of quality, 12h is impregnated at 30 DEG C, are filtered It is placed at shady and cool ventilation and air-dries again afterwards；

II, adds in the 1wt% ammonia spirits of 10 times of quality, extracts 2h at 95 DEG C, filtrate, the same condition of filter residue is collected by filtration It extracts again, merges filtrate twice；

Above-mentioned filtrate is placed in progress pre-freeze 40min, the condenser temperature of vacuum freeze drying in vacuum freeze drier by III, For subzero 55 DEG C, vacuum degree 0.19Pa, dry 7h obtains the Black Ganoderma extract.

A kind of production technology of Ms's anticreep shampoo, comprises the following steps：

I, weighs each component raw material by formula；

II, is by 85wt% water, laureth sulfuric ester ammonium, bay alcohol sulfuric ester ammonium, sodium lauroyl sarcosine, EDTA bis- Sodium is added in homogenizer, and 15min is stirred under conditions of rotating speed 240r/min, 80 DEG C of temperature；

III, continue into homogenizer add in glycol distearate, cetostearyl alcohol, methyl hydroxybenzoate, keep temperature and Rotating speed is constant, stirs 20min；

IV, is cooled to 70 DEG C, add in Cocoamidopropyl betaine, sodium chloride, guar hydroxypropyltrimonium chloride, Panthenol, citric acid stir 20min with the rotating speed of 200r/min；

V, is down to 50 DEG C when temperature, and adding in remaining water, Cacumen Platycladi extract, fleece-flower root root to above-mentioned mixed solution carries Object, Fructus Viticis extract, antioxidant are taken, 20min is stirred with the rotating speed of 200r/min, makes its fully dispersed homogenizing；

VI, adds in hydrolyzed wheat protein, essence, methylisothiazolinone to above-mentioned homogenizer when temperature is 35 DEG C In, 6min is stirred with the rotating speed of 100r/min, is cooled down while stirring, when being cooled to 27 DEG C, stops stirring；

VIII, is stood, defoaming and quality inspection, after quality inspection qualification, is transported to bottling department, is carried out by specified amount filling, obtains Ms Anticreep shampoo.

Embodiment 2

A kind of Ms's anticreep shampoo, is made of the raw material of following components by weight percent：Laureth sulfuric ester ammonium 7wt%, Bay alcohol sulfuric ester ammonium 7wt%, sodium lauroyl sarcosine 2.5wt%, Cocoamidopropyl betaine 1.5wt%, ethylene glycol two Stearate 1.2wt%, guar hydroxypropyltrimonium chloride 1wt%, sodium chloride 0.75wt%, hydrolyzed wheat protein 0.5wt%, essence 0.4wt%, panthenol 0.3wt%, cetostearyl alcohol 0.3wt%, citric acid 0.15wt%, EDETATE SODIUM 0.1wt%, methyl hydroxybenzoate 0.06wt%, methylisothiazolinone 0.006wt%, Cacumen Platycladi extract 1.5wt%, fleece-flower root root Extract 1.5wt%, antioxidant 1wt%, surplus are water.

The Cacumen Platycladi extract is prepared by the following method to obtain：Arbor-vitae leaf raw material is taken, cleans and is added to the water after drying It decocts 3 times, first time decocting time is 160min, and second of decocting time is 90min, and third time decocting time is 45min, often Secondary to decoct add the weight of water for arbor-vitae leaf raw material 10 times, it is 1.21 that relative density is then concentrated under reduced pressure at a temperature of 50 DEG C Concentrate is dried with spray drying process, and inlet air temperature and leaving air temp are respectively 160 DEG C, 70 DEG C, and obtaining cacumen biotae after dry carries Take object.

The fleece-flower root root extract why Polygonum Multiflorum root enzymatic hydrolyzed extract, the preparation side of the fleece-flower root root enzymatic hydrolyzed extract Method comprises the following steps：

I, is weighed to dry after fleece-flower root root is cleaned and crushed, and the water of 2 times of quality is added in into fleece-flower root root powder, 30 15min is stirred with 200r/min rotating speeds at a temperature of DEG C, obtains fleece-flower root root powder suspension；

Fleece-flower root root powder suspension obtained above is moved into homogenizer, homogeneous 7min by II, and homogenization pressure is 100MPa adds in the 0.3wt% complex enzyme agent of fleece-flower root root mixed liquor quality in the fleece-flower root mixed liquor after homogeneous, wherein compound It is 1 in mass ratio by neutral proteinase and cellulase that enzyme agent, which is,：2, then with concentration be 0.5mo1/L acetums adjust pH to 4.5, the sealing enzymolysis 70min at 40 DEG C is then placed in drying box；

Removal filter residue is separated by filtration after the completion of III, enzymolysis, obtains enzymolysis liquid, will be surpassed under conditions of 25 DEG C of enzymolysis liquid Filtrate is collected in filter；

Filtrate after above-mentioned ultrafiltration and absolute ethyl alcohol are 1 by volume by IV,:1 is mixed, then in ultrasonic power Then at 480W Microwave Extraction 10min, rotation is put into after the completion of alcohol extracting by 600W, ultrasonic extraction 20min under the conditions of 45 DEG C for mixed liquor Evaporator rotates 1.5h at a temperature of 50 DEG C, recycles absolute ethyl alcohol, and concentration is until mixeding liquid volume becomes former mixeding liquid volume 1/8, obtain concentrate；

Above-mentioned concentrate is freeze-dried 35min by V, at a temperature of subzero 35 DEG C, is pulverized after dry and is crossed 200 Mesh standard sieve is to get fleece-flower root root enzymatic hydrolyzed extract.

The antioxidant is gadol extract and Black Ganoderma extract, wherein gadol extract and Black Ganoderma extraction Amount of substance ratio is 1：1.

The gadol extract is prepared by the following method to obtain：Rhodiola root raw material is taken, cleans and is added in after drying 65wt% alcohol refluxs extract 3 times, extraction time 75min, and each Extracting temperature is 50 DEG C, and rhodiola root is former during extraction every time The rate of charge of material and ethyl alcohol is 1：8 (g/ml) are filtered after the completion of extraction, are then combined with extracting solution, nothing is concentrated into after being concentrated under reduced pressure Alcohol taste is dried to constant weight at a temperature of 65 DEG C, obtains gadol extract.

The preparation method of the Black Ganoderma extract comprises the following steps：

I, is put into baking oven after Black Ganoderma fructification is cut into slices and dries, and then puts into pulverizer and carries out fine crushing, powder 40 mesh are broken to, gained Black Ganoderma powder are put into the 95wt% ethanol solutions of 10 times of quality, 12h is impregnated at 30 DEG C, are filtered It is placed at shady and cool ventilation and air-dries again afterwards；

II, adds in the 1wt% ammonia spirits of 10 times of quality, extracts 2h at 95 DEG C, filtrate, the same condition of filter residue is collected by filtration It extracts again, merges filtrate twice；

Above-mentioned filtrate is placed in progress pre-freeze 40min, the condenser temperature of vacuum freeze drying in vacuum freeze drier by III, For subzero 55 DEG C, vacuum degree 0.19Pa, dry 7h obtains the Black Ganoderma extract.

A kind of production technology of Ms's anticreep shampoo, comprises the following steps：

I, weighs each component raw material by formula；

II, is by 85wt% water, laureth sulfuric ester ammonium, bay alcohol sulfuric ester ammonium, sodium lauroyl sarcosine, EDTA bis- Sodium is added in homogenizer, and 15min is stirred under conditions of rotating speed 240r/min, 80 DEG C of temperature；

III, continue into homogenizer add in glycol distearate, cetostearyl alcohol, methyl hydroxybenzoate, keep temperature and Rotating speed is constant, stirs 20min；

IV, is cooled to 70 DEG C, add in Cocoamidopropyl betaine, sodium chloride, guar hydroxypropyltrimonium chloride, Panthenol, citric acid stir 20min with the rotating speed of 200r/min；

V, is down to 50 DEG C when temperature, and adding in remaining water, Cacumen Platycladi extract, fleece-flower root root to above-mentioned mixed solution carries Object, antioxidant are taken, 20min is stirred with the rotating speed of 200r/min, makes its fully dispersed homogenizing；

VI, adds in hydrolyzed wheat protein, essence, methylisothiazolinone to above-mentioned homogenizer when temperature is 35 DEG C In, 6min is stirred with the rotating speed of 100r/min, is cooled down while stirring, when being cooled to 27 DEG C, stops stirring；

VIII, is stood, defoaming and quality inspection, after quality inspection qualification, is transported to bottling department, is carried out by specified amount filling, obtains Ms Anticreep shampoo.

Embodiment 3

A kind of Ms's anticreep shampoo, is made of the raw material of following components by weight percent：Laureth sulfuric ester ammonium 7wt%, Bay alcohol sulfuric ester ammonium 7wt%, sodium lauroyl sarcosine 2.5wt%, Cocoamidopropyl betaine 1.5wt%, ethylene glycol two Stearate 1.2wt%, guar hydroxypropyltrimonium chloride 1wt%, sodium chloride 0.75wt%, hydrolyzed wheat protein 0.5wt%, essence 0.4wt%, panthenol 0.3wt%, cetostearyl alcohol 0.3wt%, citric acid 0.15wt%, EDETATE SODIUM 0.1wt%, methyl hydroxybenzoate 0.06wt%, methylisothiazolinone 0.006wt%, fleece-flower root root extract 1.5wt%, fructus viticis Extract 1.5wt%, antioxidant 1wt%, surplus are water.

The fleece-flower root root extract why Polygonum Multiflorum root enzymatic hydrolyzed extract, the preparation side of the fleece-flower root root enzymatic hydrolyzed extract Method comprises the following steps：

I, is weighed to dry after fleece-flower root root is cleaned and crushed, and the water of 2 times of quality is added in into fleece-flower root root powder, 30 15min is stirred with 200r/min rotating speeds at a temperature of DEG C, obtains fleece-flower root root powder suspension；

Fleece-flower root root powder suspension obtained above is moved into homogenizer, homogeneous 7min by II, and homogenization pressure is 100MPa adds in the 0.3wt% complex enzyme agent of fleece-flower root root mixed liquor quality in the fleece-flower root mixed liquor after homogeneous, wherein compound It is 1 in mass ratio by neutral proteinase and cellulase that enzyme agent, which is,：2, then with concentration be 0.5mo1/L acetums adjust pH to 4.5, the sealing enzymolysis 70min at 40 DEG C is then placed in drying box；

Removal filter residue is separated by filtration after the completion of III, enzymolysis, obtains enzymolysis liquid, will be surpassed under conditions of 25 DEG C of enzymolysis liquid Filtrate is collected in filter；

Filtrate after above-mentioned ultrafiltration and absolute ethyl alcohol are 1 by volume by IV,:1 is mixed, then in ultrasonic power Then at 480W Microwave Extraction 10min, rotation is put into after the completion of alcohol extracting by 600W, ultrasonic extraction 20min under the conditions of 45 DEG C for mixed liquor Evaporator rotates 1.5h at a temperature of 50 DEG C, recycles absolute ethyl alcohol, and concentration is until mixeding liquid volume becomes former mixeding liquid volume 1/8, obtain concentrate；

Above-mentioned concentrate is freeze-dried 35min by V, at a temperature of subzero 35 DEG C, is pulverized after dry and is crossed 200 Mesh standard sieve is to get fleece-flower root root enzymatic hydrolyzed extract.

The Fructus Viticis extract is prepared by the following method to obtain：By fresh fructus viticis natural air drying, 40 mesh are crushed to, By 1:60 weight ratios add in boiling water and carry out 3 decoctions, and decocting time difference 50min decocts hydration simultaneously every time, is concentrated under reduced pressure to be climing 60 times of chaste tree protonatomic mass add in the absolute ethyl alcohol of 2 times of quality, and 6h is refrigerated at 2-8 DEG C, and centrifugation removal precipitation then depressurizes back Ethyl alcohol is received, is concentrated into no alcohol taste, is dried at a temperature of 80 DEG C to constant weight, obtains Fructus Viticis extract.

The antioxidant is gadol extract and Black Ganoderma extract, wherein gadol extract and Black Ganoderma extraction Amount of substance ratio is 1：1.

The gadol extract is prepared by the following method to obtain：Rhodiola root raw material is taken, cleans and is added in after drying 65wt% alcohol refluxs extract 3 times, extraction time 75min, and each Extracting temperature is 50 DEG C, and rhodiola root is former during extraction every time The rate of charge of material and ethyl alcohol is 1：8 (g/ml) are filtered after the completion of extraction, are then combined with extracting solution, nothing is concentrated into after being concentrated under reduced pressure Alcohol taste is dried to constant weight at a temperature of 65 DEG C, obtains gadol extract.

The preparation method of the Black Ganoderma extract comprises the following steps：

I, is put into baking oven after Black Ganoderma fructification is cut into slices and dries, and then puts into pulverizer and carries out fine crushing, powder 40 mesh are broken to, gained Black Ganoderma powder are put into the 95wt% ethanol solutions of 10 times of quality, 12h is impregnated at 30 DEG C, are filtered It is placed at shady and cool ventilation and air-dries again afterwards；

II, adds in the 1wt% ammonia spirits of 10 times of quality, extracts 2h, filtrate is collected by filtration, filter residue carries again with condition It takes, merges filtrate twice；

Above-mentioned filtrate is placed in progress pre-freeze 40min, the condenser temperature of vacuum freeze drying in vacuum freeze drier by III, For subzero 55 DEG C, vacuum degree 0.19Pa, dry 7h obtains the Black Ganoderma extract.

A kind of production technology of Ms's anticreep shampoo, comprises the following steps：

I, weighs each component raw material by formula；

II, is by 85wt% water, laureth sulfuric ester ammonium, bay alcohol sulfuric ester ammonium, sodium lauroyl sarcosine, EDTA bis- Sodium is added in homogenizer, and 15min is stirred under conditions of rotating speed 240r/min, 80 DEG C of temperature；

III, continue into homogenizer add in glycol distearate, cetostearyl alcohol, methyl hydroxybenzoate, keep temperature and Rotating speed is constant, stirs 20min；

IV, is cooled to 70 DEG C, add in Cocoamidopropyl betaine, sodium chloride, guar hydroxypropyltrimonium chloride, Panthenol, citric acid stir 20min with the rotating speed of 200r/min；

V, is down to 50 DEG C when temperature, and adding in remaining water, fleece-flower root root extract, fructus viticis to above-mentioned mixed solution carries Object, antioxidant are taken, 20min is stirred with the rotating speed of 200r/min, makes its fully dispersed homogenizing；

VI, adds in hydrolyzed wheat protein, essence, methylisothiazolinone to above-mentioned homogenizer when temperature is 35 DEG C In, 6min is stirred with the rotating speed of 100r/min, is cooled down while stirring, when being cooled to 27 DEG C, stops stirring；

VIII, is stood, defoaming and quality inspection, after quality inspection qualification, is transported to bottling department, is carried out by specified amount filling, obtains Ms Anticreep shampoo.

Embodiment 4

A kind of Ms's anticreep shampoo, is made of the raw material of following components by weight percent：Laureth sulfuric ester ammonium 7wt%, Bay alcohol sulfuric ester ammonium 7wt%, sodium lauroyl sarcosine 2.5wt%, Cocoamidopropyl betaine 1.5wt%, ethylene glycol two Stearate 1.2wt%, guar hydroxypropyltrimonium chloride 1wt%, sodium chloride 0.75wt%, hydrolyzed wheat protein 0.5wt%, essence 0.4wt%, panthenol 0.3wt%, cetostearyl alcohol 0.3wt%, citric acid 0.15wt%, EDETATE SODIUM 0.1wt%, methyl hydroxybenzoate 0.06wt%, methylisothiazolinone 0.006wt%, Cacumen Platycladi extract 1.5wt%, fructus viticis carry It is water to take object 1.5wt%, antioxidant 1wt%, surplus.

The Cacumen Platycladi extract is prepared by the following method to obtain：Arbor-vitae leaf raw material is taken, cleans and is added to the water after drying It decocts 3 times, first time decocting time is 160min, and second of decocting time is 90min, and third time decocting time is 45min, often Secondary to decoct add the weight of water for arbor-vitae leaf raw material 10 times, it is 1.21 that relative density is then concentrated under reduced pressure at a temperature of 50 DEG C Concentrate is dried with spray drying process, and inlet air temperature and leaving air temp are respectively 160 DEG C, 70 DEG C, and obtaining cacumen biotae after dry carries Take object.

The Fructus Viticis extract is prepared by the following method to obtain：By fresh fructus viticis natural air drying, 40 mesh are crushed to, By 1:60 weight ratios add in boiling water and carry out 3 decoctions, and decocting time difference 50min decocts hydration simultaneously every time, is concentrated under reduced pressure to be climing 60 times of chaste tree protonatomic mass add in the absolute ethyl alcohol of 2 times of quality, and 6h is refrigerated at 2-8 DEG C, and centrifugation removal precipitation then depressurizes back Ethyl alcohol is received, is concentrated into no alcohol taste, is dried at a temperature of 80 DEG C to constant weight, obtains Fructus Viticis extract.

The antioxidant is gadol extract and Black Ganoderma extract, wherein gadol extract and Black Ganoderma extraction Amount of substance ratio is 1：1.

The gadol extract is prepared by the following method to obtain：Rhodiola root raw material is taken, cleans and is added in after drying 65wt% alcohol refluxs extract 3 times, extraction time 75min, and each Extracting temperature is 50 DEG C, and rhodiola root is former during extraction every time The rate of charge of material and ethyl alcohol is 1：8 (g/ml) are filtered after the completion of extraction, are then combined with extracting solution, nothing is concentrated into after being concentrated under reduced pressure Alcohol taste is dried to constant weight at a temperature of 65 DEG C, obtains gadol extract.

The preparation method of the Black Ganoderma extract comprises the following steps：

I, is put into baking oven after Black Ganoderma fructification is cut into slices and dries, and then puts into pulverizer and carries out fine crushing, powder 40 mesh are broken to, gained Black Ganoderma powder are put into the 95wt% ethanol solutions of 10 times of quality, 12h is impregnated at 30 DEG C, are filtered It is placed at shady and cool ventilation and air-dries again afterwards；

II, adds in the 1wt% ammonia spirits of 10 times of quality, extracts 2h at 95 DEG C, filtrate, the same condition of filter residue is collected by filtration It extracts again, merges filtrate twice；

Above-mentioned filtrate is placed in progress pre-freeze 40min, the condenser temperature of vacuum freeze drying in vacuum freeze drier by III, For subzero 55 DEG C, vacuum degree 0.19Pa, dry 7h obtains the Black Ganoderma extract.

A kind of production technology of Ms's anticreep shampoo, comprises the following steps：

I, weighs each component raw material by formula；

II, is by 85wt% water, laureth sulfuric ester ammonium, bay alcohol sulfuric ester ammonium, sodium lauroyl sarcosine, EDTA bis- Sodium is added in homogenizer, and 15min is stirred under conditions of rotating speed 240r/min, 80 DEG C of temperature；

III, continue into homogenizer add in glycol distearate, cetostearyl alcohol, methyl hydroxybenzoate, keep temperature and Rotating speed is constant, stirs 20min；

IV, is cooled to 70 DEG C, add in Cocoamidopropyl betaine, sodium chloride, guar hydroxypropyltrimonium chloride, Panthenol, citric acid stir 20min with the rotating speed of 200r/min；

V, is down to 50 DEG C when temperature, and adding in remaining water, Cacumen Platycladi extract, fructus viticis to above-mentioned mixed solution extracts Object, antioxidant stir 20min with the rotating speed of 200r/min, make its fully dispersed homogenizing；

VI, adds in hydrolyzed wheat protein, essence, methylisothiazolinone to above-mentioned homogenizer when temperature is 35 DEG C In, 6min is stirred with the rotating speed of 100r/min, is cooled down while stirring, when being cooled to 27 DEG C, stops stirring；

VIII, is stood, defoaming and quality inspection, after quality inspection qualification, is transported to bottling department, is carried out by specified amount filling, obtains Ms Anticreep shampoo.

Comparative example 1

A kind of Ms's anticreep shampoo, is made of the raw material of following components by weight percent：Laureth sulfuric ester ammonium 7wt%, Bay alcohol sulfuric ester ammonium 7wt%, sodium lauroyl sarcosine 2.5wt%, Cocoamidopropyl betaine 1.5wt%, ethylene glycol two Stearate 1.2wt%, guar hydroxypropyltrimonium chloride 1wt%, sodium chloride 0.75wt%, hydrolyzed wheat protein 0.5wt%, essence 0.4wt%, panthenol 0.3wt%, cetostearyl alcohol 0.3wt%, citric acid 0.15wt%, EDETATE SODIUM 0.1wt%, methyl hydroxybenzoate 0.06wt%, methylisothiazolinone 0.006wt%, antioxidant 1wt%, surplus are water.

The antioxidant is gadol extract and Black Ganoderma extract, wherein gadol extract and Black Ganoderma extraction Amount of substance ratio is 1：1.

The gadol extract is prepared by the following method to obtain：Rhodiola root raw material is taken, cleans and is added in after drying 65wt% alcohol refluxs extract 3 times, extraction time 75min, and each Extracting temperature is 50 DEG C, and rhodiola root is former during extraction every time The rate of charge of material and ethyl alcohol is 1：8 (g/ml) are filtered after the completion of extraction, are then combined with extracting solution, nothing is concentrated into after being concentrated under reduced pressure Alcohol taste is dried to constant weight at a temperature of 65 DEG C, obtains gadol extract.

The preparation method of the Black Ganoderma extract comprises the following steps：

I, is put into baking oven after Black Ganoderma fructification is cut into slices and dries, and then puts into pulverizer and carries out fine crushing, powder 40 mesh are broken to, gained Black Ganoderma powder are put into the 95wt% ethanol solutions of 10 times of quality, 12h is impregnated at 30 DEG C, are filtered It is placed at shady and cool ventilation and air-dries again afterwards；

II, adds in the 1wt% ammonia spirits of 10 times of quality, extracts 2h at 95 DEG C, filtrate, the same condition of filter residue is collected by filtration It extracts again, merges filtrate twice；

Above-mentioned filtrate is placed in progress pre-freeze 40min, the condenser temperature of vacuum freeze drying in vacuum freeze drier by III, For subzero 55 DEG C, vacuum degree 0.19Pa, dry 7h obtains the Black Ganoderma extract.

A kind of production technology of Ms's anticreep shampoo, comprises the following steps：

I, weighs each component raw material by formula；

II, is by 85wt% water, laureth sulfuric ester ammonium, bay alcohol sulfuric ester ammonium, sodium lauroyl sarcosine, EDTA bis- Sodium is added in homogenizer, and 15min is stirred under conditions of rotating speed 240r/min, 80 DEG C of temperature；

III, continue into homogenizer add in glycol distearate, cetostearyl alcohol, methyl hydroxybenzoate, keep temperature and Rotating speed is constant, stirs 20min；

IV, is cooled to 70 DEG C, add in Cocoamidopropyl betaine, sodium chloride, guar hydroxypropyltrimonium chloride, Panthenol, citric acid stir 20min with the rotating speed of 200r/min；

V, is down to 50 DEG C when temperature, and remaining water, antioxidant are added in above-mentioned mixed solution, with turning for 200r/min Speed stirring 20min, makes its fully dispersed homogenizing；

VI, adds in hydrolyzed wheat protein, essence, methylisothiazolinone to above-mentioned homogenizer when temperature is 35 DEG C In, 6min is stirred with the rotating speed of 100r/min, is cooled down while stirring, when being cooled to 27 DEG C, stops stirring；

VIII, is stood, defoaming and quality inspection, after quality inspection qualification, is transported to bottling department, is carried out by specified amount filling, obtains Ms Anticreep shampoo.

Embodiment 5

It is substantially the same manner as Example 1, it differs only in：The fleece-flower root root extract why Polygonum Multiflorum root impalpable powder, institute The preparation process for stating fleece-flower root root impalpable powder is：After fleece-flower root root is taken to clean, 20 mesh are crushed to, oscillatory type drug is subsequently placed in and surpasses In atomizer under conditions of subzero 10 DEG C ultramicro grinding 45min, it is 12 μm of fleece-flower root root impalpable powder to obtain average grain diameter.

Embodiment 6

It is substantially the same manner as Example 1, it differs only in：The preparation method of the fleece-flower root root enzymatic hydrolyzed extract include with Lower step：

I, is weighed to dry after fleece-flower root root is cleaned and crushed, and the water of 2 times of quality is added in into fleece-flower root root powder, 30 15min is stirred with 200r/min rotating speeds at a temperature of DEG C, obtains fleece-flower root root powder suspension；

Fleece-flower root root powder suspension obtained above is moved into homogenizer, homogeneous 7min by II, and homogenization pressure is 100MPa adds in the 0.3wt% complex enzyme agent of fleece-flower root root mixed liquor quality in the fleece-flower root mixed liquor after homogeneous, wherein compound It is 1 in mass ratio by neutral proteinase and cellulase that enzyme agent, which is,：2, then with concentration be 0.5mo1/L acetums adjust pH to 4.5, the sealing enzymolysis 70min at 40 DEG C is then placed in drying box；

Removal filter residue is separated by filtration after the completion of III, enzymolysis, obtains enzymolysis liquid, will be surpassed under conditions of 25 DEG C of enzymolysis liquid Filtrate is collected in filter；

Above-mentioned filtrate is put into rotary evaporator by IV, and 1.5h is rotated at a temperature of 50 DEG C, recycles absolute ethyl alcohol, and concentration is straight Become the 1/8 of original volume to mixeding liquid volume, obtain concentrate；

Above-mentioned concentrate is freeze-dried 35min by V, at a temperature of subzero 35 DEG C, is pulverized after dry and is crossed 200 Mesh standard sieve is to get fleece-flower root root enzymatic hydrolyzed extract.

Embodiment 7

It is substantially the same manner as Example 1, it differs only in：The antioxidant be gadol extract, the rhodiola root Extract is prepared by the following method to obtain：Rhodiola root raw material is taken, cleans and 65wt% alcohol refluxs extraction 3 times is added in after drying, Extraction time is 75min, and each Extracting temperature is 50 DEG C, and the rate of charge of rhodiola root raw material and ethyl alcohol is 1 during extraction every time：8 (g/ml), filtered after the completion of extraction, be then combined with extracting solution, no alcohol taste is concentrated into after being concentrated under reduced pressure, it is dry at a temperature of 65 DEG C To constant weight, gadol extract is obtained.

Embodiment 8

It is substantially the same manner as Example 1, it differs only in：The antioxidant be Black Ganoderma extract, the Black Ganoderma The preparation method of extract comprises the following steps：

I, is put into baking oven after Black Ganoderma fructification is cut into slices and dries, and then puts into pulverizer and carries out fine crushing, powder 40 mesh are broken to, gained Black Ganoderma powder are put into the 95wt% ethanol solutions of 10 times of quality, 12h is impregnated at 30 DEG C, are filtered It is placed at shady and cool ventilation and air-dries again afterwards；

II, adds in the 1wt% ammonia spirits of 10 times of quality, extracts 2h at 95 DEG C, filtrate, the same condition of filter residue is collected by filtration It extracts again, merges filtrate twice；

Above-mentioned filtrate is placed in progress pre-freeze 40min, the condenser temperature of vacuum freeze drying in vacuum freeze drier by III, For subzero 55 DEG C, vacuum degree 0.19Pa, dry 7h obtains the Black Ganoderma extract.

The gadol extract is prepared by the following method to obtain：Rhodiola root raw material is taken, cleans and is added in after drying 65wt% alcohol refluxs extract 3 times, extraction time 75min, and each Extracting temperature is 50 DEG C, and rhodiola root is former during extraction every time The rate of charge of material and ethyl alcohol is 1：8 (g/ml) are filtered after the completion of extraction, are then combined with extracting solution, nothing is concentrated into after being concentrated under reduced pressure Alcohol taste is dried to constant weight at a temperature of 65 DEG C, obtains gadol extract.

Comparative example 2

A kind of Ms's anticreep shampoo, is made of the raw material of following components by weight percent：Laureth sulfuric ester ammonium 7wt%, Bay alcohol sulfuric ester ammonium 7wt%, sodium lauroyl sarcosine 2.5wt%, Cocoamidopropyl betaine 1.5wt%, ethylene glycol two Stearate 1.2wt%, guar hydroxypropyltrimonium chloride 1wt%, sodium chloride 0.75wt%, hydrolyzed wheat protein 0.5wt%, essence 0.4wt%, panthenol 0.3wt%, cetostearyl alcohol 0.3wt%, citric acid 0.15wt%, EDETATE SODIUM 0.1wt%, methyl hydroxybenzoate 0.06wt%, methylisothiazolinone 0.006wt%, Cacumen Platycladi extract 1wt%, fleece-flower root root carry It is water to take object 1wt%, Fructus Viticis extract 1wt%, surplus.

The Cacumen Platycladi extract is prepared by the following method to obtain：Arbor-vitae leaf raw material is taken, cleans and is added to the water after drying It decocts 3 times, first time decocting time is 160min, and second of decocting time is 90min, and third time decocting time is 45min, often Secondary to decoct add the weight of water for arbor-vitae leaf raw material 10 times, it is 1.21 that relative density is then concentrated under reduced pressure at a temperature of 50 DEG C Concentrate is dried with spray drying process, and inlet air temperature and leaving air temp are respectively 160 DEG C, 70 DEG C, and obtaining cacumen biotae after dry carries Take object.

The fleece-flower root root extract why Polygonum Multiflorum root enzymatic hydrolyzed extract, the preparation side of the fleece-flower root root enzymatic hydrolyzed extract Method comprises the following steps：

I, is weighed to dry after fleece-flower root root is cleaned and crushed, and the water of 2 times of quality is added in into fleece-flower root root powder, 30 15min is stirred with 200r/min rotating speeds at a temperature of DEG C, obtains fleece-flower root root powder suspension；

Fleece-flower root root powder suspension obtained above is moved into homogenizer, homogeneous 7min by II, and homogenization pressure is 100MPa adds in the 0.3wt% complex enzyme agent of fleece-flower root root mixed liquor quality in the fleece-flower root mixed liquor after homogeneous, wherein compound It is 1 in mass ratio by neutral proteinase and cellulase that enzyme agent, which is,：2, then with concentration be 0.5mo1/L acetums adjust pH to 4.5, the sealing enzymolysis 70min at 40 DEG C is then placed in drying box；

Removal filter residue is separated by filtration after the completion of III, enzymolysis, obtains enzymolysis liquid, will be surpassed under conditions of 25 DEG C of enzymolysis liquid Filtrate is collected in filter；

Filtrate after above-mentioned ultrafiltration and absolute ethyl alcohol are 1 by volume by IV,:1 is mixed, then in ultrasonic power Then at 480W Microwave Extraction 10min, rotation is put into after the completion of alcohol extracting by 600W, ultrasonic extraction 20min under the conditions of 45 DEG C for mixed liquor Evaporator rotates 1.5h at a temperature of 50 DEG C, recycles absolute ethyl alcohol, and concentration is until mixeding liquid volume becomes former mixeding liquid volume 1/8, obtain concentrate；

Above-mentioned concentrate is freeze-dried 35min by V, at a temperature of subzero 35 DEG C, is pulverized after dry and is crossed 200 Mesh standard sieve is to get fleece-flower root root enzymatic hydrolyzed extract.

The Fructus Viticis extract is prepared by the following method to obtain：By fresh fructus viticis natural air drying, 40 mesh are crushed to, By 1:60 weight ratios add in boiling water and carry out 3 decoctions, and decocting time difference 50min decocts hydration simultaneously every time, is concentrated under reduced pressure to be climing 60 times of chaste tree protonatomic mass add in the absolute ethyl alcohol of 2 times of quality, and 6h is refrigerated at 2-8 DEG C, and centrifugation removal precipitation then depressurizes back Ethyl alcohol is received, is concentrated into no alcohol taste, is dried at a temperature of 80 DEG C to constant weight, obtains Fructus Viticis extract.

A kind of production technology of Ms's anticreep shampoo, comprises the following steps：

I, weighs each component raw material by formula；

II, is by 85wt% water, laureth sulfuric ester ammonium, bay alcohol sulfuric ester ammonium, sodium lauroyl sarcosine, EDTA bis- Sodium is added in homogenizer, and 15min is stirred under conditions of rotating speed 240r/min, 80 DEG C of temperature；

III, continue into homogenizer add in glycol distearate, cetostearyl alcohol, methyl hydroxybenzoate, keep temperature and Rotating speed is constant, stirs 20min；

IV, is cooled to 70 DEG C, add in Cocoamidopropyl betaine, sodium chloride, guar hydroxypropyltrimonium chloride, Panthenol, citric acid stir 20min with the rotating speed of 200r/min；

V, is down to 50 DEG C when temperature, and adding in remaining water, Cacumen Platycladi extract, fleece-flower root root to above-mentioned mixed solution carries Object, Fructus Viticis extract are taken, 20min is stirred with the rotating speed of 200r/min, makes its fully dispersed homogenizing；

VI, adds in hydrolyzed wheat protein, essence, methylisothiazolinone to above-mentioned homogenizer when temperature is 35 DEG C In, 6min is stirred with the rotating speed of 100r/min, is cooled down while stirring, when being cooled to 27 DEG C, stops stirring；

VIII, is stood, defoaming and quality inspection, after quality inspection qualification, is transported to bottling department, is carried out by specified amount filling, obtains Ms Anticreep shampoo.

Test case 1

The measure of Stibene-glucoside, emodin content：The fleece-flower root also known as knotweed, purple black rattan, Polygonum multiflower knotweed etc. are spent more, be polygonaceae The fleece-flower root is added in washing product the telangiectasis that can make head, prevents hair from bleaching, can increase by knotweed race liana Add the nutrition of hair, improve the toughness of hair, reduce alopecia, disconnected hair, there is protective effect to the hair of damage, because the fleece-flower root Active ingredient in Stibene-glucoside, dissociated anthraquinone (such as rheum emodin), lecithin.With reference to the journal of writings of Chen Qingtang《He Shou The changes of contents of 5 kinds of chemical compositions in black concocting process》In 2 section in experimental method have one's hair wash to Ms's anticreep in embodiment 1-8 Stibene-glucoside, the emodin content of dew are measured.

Table 1：The measure of Stibene-glucoside, emodin content

	Stibene-glucoside (mg/g)	Rheum emodin (mg/g)
			Embodiment 1	0.16	0.037
Embodiment 4	0	0
			Embodiment 5	0.04	0.015
Embodiment 6	0.08	0.021

As shown in Table 1, embodiment 1 (fleece-flower root root extract is prepared by enzymolysis, ultrasonic microwave collaboration extraction) In per Mrs g anticreep shampoo in containing 0.12mg Stibene-glucosides, 0.037mg rheum emodins, all higher than the 5 (fleece-flower root of embodiment Root is directly ground to impalpable powder),

Embodiment 6 (fleece-flower root root extract is only prepared by enzymolysis) and embodiment 4 (are extracted without fleece-flower root root Object), this is probably due in fleece-flower root root impalpable powder without separation, purification process, and macromolecular substances and other impurity are more, And fleece-flower root root is purified by processes such as enzymolysis, ultrasonic microwave collaboration extractions, has efficiently extracted active component content, is obtained The fleece-flower root root extract of higher purity.

Test case 2

Anticreep efficacy test：In order to verify the anticreep effect of Ms's anticreep shampoo obtained by the present invention, select human body direct Mode on probation carries out contrast test.450 female volunteers are screened, at 18-50 Sui, there is apparent hair loss phenomenon at the age, Average daily hair loss 100-300 roots.Using single blind test form, 450 volunteers are randomly divided into 9 groups, each group 50 people, respectively using present invention Mrs's gained anticreep shampoo (embodiment 1-8 and comparative example 1), hair washing daily is once.Experimental period Between without using any other cosmetics influential on result, drug and health products；It can coordinate very well by the requirement of testing program Experiment, can keep regularity in one's life during research.Using follow-up is carried out after 1 month one by one, hair loss situation, specific feelings are counted Condition is shown in Table 3：

SS：" effective ", after one month, hair loss phenomenon has certain alleviation, and hair loss weight ratio reduces；" nothing Effect ", after one month, hair loss phenomenon is without any alleviation or even hair loss more serious situation occurs.Effective percentage calculates public Formula：

Effective percentage=efficiently individual quantity/total number of persons × 100%.

Table 2：Anticreep effect situation

	Effective percentage/%
		Embodiment 1	85
Embodiment 2	72
		Embodiment 3	71
Embodiment 4	73
		Embodiment 5	78
Embodiment 6	79
		Embodiment 7	82
Embodiment 8	81
		Comparative example 1	65

Can be obtained from 2 interpretation of result of table, using 1 Ms's anticreep shampoo of embodiment in the present invention using Cacumen Platycladi extract, Fleece-flower root root extract, the hair anticreep agent of Fructus Viticis extract combination, alopecia cure rate highest reaches 85%, and uses Embodiment 2-4 (agent of hair anticreep is by Cacumen Platycladi extract, the arbitrary two kinds of combinations of fleece-flower root root extract, Fructus Viticis extract) and The cure rate of comparative example 1 (agent of hair anticreep is not used) Ms's anticreep shampoo is respectively 72%, 71%, 73%, 64%, it is clear that The anticreep effect of Ms's anticreep shampoo is more notable in the embodiment of the present invention 1.

Test case 3

Stability, bactericidal properties detection：Stability to the obtained Ms's anticreep shampoo of embodiment 1-8 and comparative example 2, Bactericidal property is detected.Stability test：With reference to the journal of writings of Cao Yingfen《The double gel-type emulsion of emulsifier-free are being made up Application in product》The stability of Ms's anticreep shampoo is surveyed in the Detection of Stability method present invention in middle 2.2.2.2 sections It is fixed, the hair washing of Ms's anticreep is placed in -15 DEG C of refrigerators for 24 hours, taking-up is placed in room temperature for 24 hours again, for 1 Xun Huan.Continuous detection 3 follows Ring.Whether it is layered by visual observations product first, then observes whether product is stablized by viscosity measurements.Sterilization test：Foundation GBl5979-2002 after the Ms's anticreep shampoo prepared is placed 20min at room temperature, tests its sterilizing rate, is tested Main microorganism is Escherichia coli (ATCC 25922) and staphylococcus aureus (ATCC 6538).

The bactericidal effect of Ms's anticreep shampoo of embodiment 1-8 and comparative example 2 is tested.Concrete outcome is shown in Table 3。

Table 3：The sterilizing rate test result table of Ms's anticreep shampoo

As shown in Table 3, stability is preferable in Ms's anticreep shampoo of the present invention.Comparing embodiment 1,7-8 and comparative example 2 Sterilizing rate understand that 1 Ms's anticreep shampoo of embodiment is anti-oxidant using gadol extract and Black Ganoderma extract combination Agent, bactericidal effect, which is better than in embodiment 7-8, to be used alone gadol extract or Black Ganoderma extract and is not added with resisting The bactericidal effect of the comparative example 2 of oxidant.

Claims (10)

1. a kind of Ms's anticreep shampoo, which is characterized in that including following raw material：Water, laureth sulfuric ester ammonium, laruyl alcohol Sulfuric ester ammonium, sodium lauroyl sarcosine, Cocoamidopropyl betaine, glycol distearate, melon glue hydroxypropyl trimethylammonium Ammonium chloride, sodium chloride, hydrolyzed wheat protein, essence, panthenol, cetostearyl alcohol, citric acid, EDETATE SODIUM, methyl hydroxybenzoate, first Base isothiazolinone, the agent of hair anticreep, antioxidant.

2. a kind of Ms's anticreep shampoo, which is characterized in that be made of the raw material of following parts by weight：Laureth sulfuric ester ammonium 4-10wt%, bay alcohol sulfuric ester ammonium 4-10wt%, sodium lauroyl sarcosine 1-4wt%, Cocoamidopropyl betaine 0.5- 2.5wt%, glycol distearate 0.4-2wt%, guar hydroxypropyltrimonium chloride 0.5-1.5wt%, sodium chloride 0.3-1.2wt%, hydrolyzed wheat protein 0.2-0.8wt%, essence 0.2-0.6wt%, panthenol 0.2-0.4wt%, cetearyl alcohol Alcohol 0.2-0.4wt%, citric acid 0.05-0.25wt%, EDETATE SODIUM 0.02-0.18wt%, methyl hydroxybenzoate 0.05- 0.12wt%, methylisothiazolinone 0.005-0.01wt%, hair anticreep agent 1-5wt%, antioxidant 0.5-1.5wt%, Surplus is water.

3. a kind of Ms's anticreep shampoo according to claim 2, which is characterized in that the hair anticreep agent is cacumen biotae One or more in extract, fleece-flower root root extract, Fructus Viticis extract.

4. a kind of Ms's anticreep shampoo according to claim 2, which is characterized in that the antioxidant carries for rhodiola root Take object and/or Black Ganoderma extract.

5. a kind of Ms's anticreep shampoo according to claim 3, which is characterized in why is the fleece-flower root root extract Polygonum Multiflorum root impalpable powder and/or fleece-flower root root enzymatic hydrolyzed extract.

A kind of 6. Ms's anticreep shampoo according to claim 5, which is characterized in that the system of the fleece-flower root root impalpable powder It is for process：After fleece-flower root root is taken to clean, 20-40 mesh is crushed to, ultramicro grinding 20- under conditions of being subsequently placed in subzero 5-20 DEG C 70min obtains the fleece-flower root root impalpable powder that Average Particle Diameters are 8-14 μm.

A kind of 7. Ms's anticreep shampoo according to claim 5, which is characterized in that the fleece-flower root root enzymatic hydrolyzed extract Preparation method comprise the following steps：

I, is weighed to dry after fleece-flower root root is cleaned and crushed, and the water of 1-4 times of quality is added in into fleece-flower root root powder, in 25- 10-20min is stirred with 150-350r/min rotating speeds at a temperature of 35 DEG C, obtains fleece-flower root root powder suspension；

The above-mentioned fleece-flower root root powder suspension homogeneous 4-9min, homogenization pressure 100-110MPa are obtained fleece-flower root mixing by II, Liquid then adds in the complex enzyme agent of 0.2-0.5% fleece-flower root root mixed liquor quality in the fleece-flower root mixed liquor after homogeneous, wherein It is 1 in mass ratio by neutral proteinase and cellulase that complex enzyme agent, which is,：(1-3) is mixed, then adjusts pH to 4.0-5.0, The sealing enzymolysis 60-80min at 35-45 DEG C is then placed into drying box, obtains enzymolysis liquid；

Above-mentioned enzymolysis liquid is separated by filtration by III, is removed filter residue, is surpassed under conditions of gained filtrate then is placed in 20-30 DEG C Filter collects filtrate, obtains the filtrate after ultrafiltration；

IV, is by the filtrate after above-mentioned ultrafiltration and absolute ethyl alcohol by volume 1:(1-3) is mixed, then in ultrasonic power 400- Ultrasonic extraction 10-30min under the conditions of 600W, 35-55 DEG C, will be mixed after the completion of 360-600W Microwave Extraction 5-15min, alcohol extracting It closes liquid and 1-3h is rotated at 40-60 DEG C of temperature, recycle absolute ethyl alcohol, concentration is until mixeding liquid volume becomes former mixeding liquid volume 1/8-1/6 obtains concentrate；

V, by above-mentioned concentrate in subzero 40 DEG C-it is 30 DEG C subzero at a temperature of be freeze-dried 30-40min, be then ground to powder simultaneously 150-250 mesh standard sieves are crossed to get fleece-flower root root enzymatic hydrolyzed extract.

A kind of 8. Ms's anticreep shampoo according to claim 4, which is characterized in that the preparation of the Black Ganoderma extract Method comprises the following steps：

I, is dried after Black Ganoderma fructification is cut into slices, and is then crushed to 30-60 mesh, is obtained Black Ganoderma powder；

II, adds in the extractant of 6-14 times of quality into above-mentioned Black Ganoderma powder, extracts 1-3h at 90-98 DEG C, is collected by filtration Filtrate, filter residue extract again with condition, merge filtrate twice, obtain Black Ganoderma extracting solution；

Above-mentioned Black Ganoderma extracting solution is dried 2-10h by III, obtains the Black Ganoderma extract.

A kind of 9. Ms's anticreep shampoo according to claim 8, which is characterized in that the preparation of the Black Ganoderma extract In method, the extractant is the one or more in ethyl alcohol, ammonium hydroxide or water；The drying mode of the Black Ganoderma extracting solution is heat Air-dry the one or more in dry, freeze-drying and vacuum drying.

10. the production technology of Ms's anticreep shampoo according to any one of claim 2-9, which is characterized in that including Following steps：

I, weighs each component raw material by formula；

II, is by 80-90wt% water, laureth sulfuric ester ammonium, bay alcohol sulfuric ester ammonium, sodium lauroyl sarcosine, EDTA bis- Sodium is added in homogenizer, homogeneous 10-20min, 80-85 DEG C of whipping temp；

III, will add in glycol distearate, cetostearyl alcohol, methyl hydroxybenzoate, keep temperature, stir 10-30min；

IV, is cooled to 65-75 DEG C, add in Cocoamidopropyl betaine, sodium chloride, guar hydroxypropyltrimonium chloride, Panthenol, citric acid, stir evenly；

V, is cooled to 45-60 DEG C, adds in remaining water, the agent of hair anticreep, antioxidant, stirs evenly；

VI, is cooled to 30-40 DEG C, adds in hydrolyzed wheat protein, essence, methylisothiazolinone, stirs evenly；

VIII, is stood, defoaming and quality inspection, after quality inspection qualification, is transported to bottling department, is carried out by specified amount filling, obtains Ms's anticreep Shampoo.