CN106860088A - A kind of whitening is dispelled scar skin care item and preparation method thereof - Google Patents
A kind of whitening is dispelled scar skin care item and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
Abstract
Dispelled scar skin care item, including following component in percentage by weight the invention discloses a kind of whitening：3 o ethylascorbyls 0.01 5%；Tranexamic acid 0.01 5%；Carnosine 0.001 4%；Fructus Schisandrae Sphenantherae extract 0.001 3%；Salicylic acid 0.001 1%；Allantoin 0.1 1%；Retinyl palmitate 0.001 1%；Absolute ethyl alcohol 0.01 10%；Five-leaved chaste tree extract 0.001 2%；Auxiliary material, surplus.The compound has moisturizing, reparation, crease-resistant, whitening, the yellow, multiple efficacies such as red, scar eliminating of dispelling of dispelling.Dispelled the invention also discloses the whitening preparation method of scar skin care item, step is few, safety simple to operate, low cost.The present invention discloses a kind of face whitening and comforts trace face cream, multiple-protection isolation elite and net white mildy wash, and their preparation method again.
Description
Technical field
The present invention relates to cosmetic technical field, more particularly to a kind of whitening is dispelled scar skin care item and preparation method thereof.
Background technology
Skin plays the effect of important barrier in human body, and it can protect human body not encroached on by extraneous factor.This screen
Barrier function be a kind of function of protectiveness, it can protect human body be subject to various external irritants (such as chemicals, atmosphere pollution,
Dry environment and ultraviolet, physical injury), and can prevent excessive moisture from passing through skin from loss in vivo.
When skin runs into stimulation, the physical damnification in the external world, skin barrier is destroyed, the various physical and chemical indexs of skin
Abnormal, such as moisture of skin reduction will occur, dry, some inflammatory reactions, atopic dermatitis, contact dermatitis occur；Skin
Melanin abnormal deposition, skin is obscure, and dermal elastin, collagen are lost in, and final skin surface can form color spot, erythema
Inflammatory reaction, cutin dyskeratosis is aging.When the impairments are severe, skin can produce inflammatory factor and a large amount of free radicals, cause skin
The deposition of skin melanin, can finally generate the scar of mulberry, influence attractive in appearance.
Scar is that the skin histology of human body is subject to after extraneous various wounds, due to the damage of the factors such as physics, biology, chemistry
Evil acts on human body skin soft tissue, causes the major injury of skin soft tissue and completely voluntarily normal can not repair, and turns by fibre
Dimensional tissue is substituted to be repaired.Around skin fiber connective tissue proliferation filling, connection, support, protection in place of wound healing just
Often organize and formed.
The appearance classification of scar and performance：
1st, the dermal layer of the skin defect that depressed scar is caused mainly due to reasons such as acne, infection, wound, operations.
Visible worm-eaten sample, the recessed scar of ice piton sample after heavier acne, the visible recessed scar of pockmark sample after smallpox, varicella.
2nd, raised scars be mostly burn and scald, wound, operation or after repeated infection in dermal layer of the skin into fiber finer
The proliferative lesion of born of the same parents.It can be seen that have red protuberance, quality is hard, surface is smooth, can be with pain of itching, keloid can also be in crab foot
Sample is expanded outwardly.Have in raised scars abundant blood supply and having be higher by more than 2 times of normal skin oxygen radical and
The fibroblast of active proliferation.
3rd, it refers to a kind of scar in skin superficial layer to calm down scars, more because of skin minor abrasions or superficial high dermis
Caused by burn and scald.The performance of this scar is rough surface or has pigment change such as erythema, hickie or pigmentation, typically
Nonfunctional obstacle, but this kind of scar influences visual appearance very much.
Conventional several treating acne methods include at present：The noninvasive suture of excision scar, soft tissue expander's expansion are normal
Drug injection, scar attrition etc. in scar, scar are repaired after skin, the above method can alleviate scar hyperplasia, improve outward appearance,
But can not completely repair scar.
The content of the invention
In order to overcome the deficiencies in the prior art, first purpose of the invention is to provide a kind of whitening to dispel scar skin care item,
The compound has moisturizing, reparation, crease-resistant, whitening, the yellow, multiple efficacies such as red, scar eliminating of dispelling of dispelling.
Second object of the present invention is to provide the preparation method that scar skin care item are dispelled in a kind of whitening, and step is few, operation letter
Single safety, low cost.
Third object of the present invention is to provide a kind of multiple face whitening to comfort trace face cream, and moisturizing, whitening, yellow effect of dispelling are good,
Skin is set to be repaired well.
Fourth object of the present invention is to provide the preparation method that trace face cream is comforted in a kind of multiple face whitening, and step is few, flow
Simply, safe operation, low cost.
5th purpose of the invention is to provide a kind of multiple-protection isolation elite, can effectively prevent ultraviolet to skin
Skin is damaged, and moisturizing is ventilative, does not block pore, will not cause acne.
6th purpose of the invention is to provide the preparation method that a kind of multiple-protection isolates elite, and step is few, flow
Simply, safe operation, low cost.
7th purpose of the invention is to provide a kind of net white mildy wash, can deep enough pore, thoroughly cleaning grease and
Dirty, not tight after, moisturizing whitening effect is excellent.
8th purpose of the invention is to provide a kind of preparation method of net white mildy wash, and step is few, and flow is simple, behaviour
Make safety, low cost.
First purpose of the invention is realized using following technical scheme：
A kind of whitening is dispelled scar skin care item, including following component in percentage by weight：
Preferably, the auxiliary material is in water, NMF, surfactant, emollient, sun-screening agent, thickener and preservative
One kind or any combination.
Preferably, the NMF includes polyalcohols NMF and polysaccharide NMF；The polyalcohols NMF
It is glycerine, two glycerine, butanediol, propane diols, dipropylene glycol, sorbierite, allantoin, PEG-4000 and PPG-10 methyl Portugal
One kind or any combination in sugar ether；The polysaccharide NMF is hyaluronic acid, Sodium Hyaluronate, pulullan, trehalose
With the one kind or any combination in tamarind seed extract；The surfactant is Glyceryl stearate citrate, poly- sorb
One kind or any combination in alcohol ester -60 and fatty acid soaps；The emollient is jojoba oil, isononyl isononanoate, carbonic acid two
One kind or any combination in Octyl Nitrite, shea butter, vitamin e acetate, octyl group polymethyl siloxane and bisabolol；
The sun-screening agent be ethylhexyl methoxy cinnamate, Uvinul T 150, BEMT,
Uvinul A Plus, butylmethoxydibenzoylmethane, phenyl dibenzimidazole tetrasulfonic acid ester
Disodium, MBBT, Terephthalidene Dicamphor Sulfonic Acid, zinc oxide, titanium dioxide,
One kind or any combination in octyl salicylate, Homosalate and Octocrilene；The thickener is Carbomer, acrylic acid
One kind in (ester) class/C10-30 alkylol acrylamide acid esters cross-linked polymers and AVC or
Any combination；The preservative includes one kind or any group in benzoic acid, benzoate, Phenoxyethanol and Sensiva SC50
Close.
Whitening provided by the present invention is dispelled scar skin care item, and the mutually coordinated effect of each component can be produced and dispel cutaneous scars, is promoted
Enter skin wound healing, desalinate the effect of scar.Except scar method is as follows：
The first step：Decompose, remove, substitute aging, fibrosis non-functional scar tissue；
Second step：The ecological environment of normal skin is set up, promotes cytothesis function, promote wound healing, increase collagen
The synthesis of albumen, repairs skin barrier；
3rd step：Stimulate circulation, suppress pigment anomaly deposition, recover normal skin tone, reduce skin health state.
Second object of the present invention is realized using following technical scheme：
A kind of whitening is dispelled the preparation method of scar skin care item, when the auxiliary material is water, is comprised the following steps：
1) A phases are prepared：At normal temperatures, by the 3-o- ethylascorbyls of formula ratio, allantoin, tranexamic acid, carnosine, south five
Taste seed extract and five-leaved chaste tree extract are placed in the first container, are subsequently adding the water of formula ratio, and stirring and dissolving obtains A phases；
2) B phases are prepared：At normal temperatures, the retinyl palmitate and salicylic acid of formula ratio are placed in second container, so
The ethanol of formula ratio is added afterwards, and stirring and dissolving obtains B phases；
3) mix：The temperature of A phases and B phases is adjusted to 25-35 DEG C, is then mixed, stirred, obtained final product.
Third object of the present invention is realized using following technical scheme：
Trace face cream is comforted in a kind of multiple face whitening, and it includes the following composition based on weight/mass percentage composition：
Main component：
Auxiliary material：
Preferably, trace face cream is comforted in the multiple face whitening includes the following composition based on weight/mass percentage composition：
Main component：
Auxiliary material：
Fourth object of the present invention is realized using following technical scheme：
The preparation method of trace face cream is comforted in a kind of multiple face whitening, is comprised the following steps：
1) prefabricated solution A is prepared：In the first container, vitamin e acetate, bisabolol and the retinol of formula ratio are added
Palmitate, stirring and dissolving obtains prefabricated solution A；
2) prefabricated solution B is prepared：In second container, the salicylic acid and absolute ethyl alcohol of formula ratio are added, stirring and dissolving is obtained
Prefabricated solution B；
3) prefabricated solution C is prepared：It is two parts the moisture of formula ratio, Part I water and Part II water is designated as respectively；
In the 3rd container, 3-o- ethylascorbyls, tranexamic acid, carnosine, Fructus Schisandrae Sphenantherae extract and the five-leaved chaste tree of formula ratio is added to carry
Thing, and Part I water are taken, stirring and dissolving obtains prefabricated solution C；
4) oil phase is prepared：In the 4th container, jojoba oil, isononyl isononanoate, the carbonic acid diethyl of formula ratio are added
Own ester, shea butter, octyl group polymethyl siloxane and Glyceryl stearate citrate, are heated to 80-85 DEG C, stirring and dissolving,
Obtain oil phase；
5) water phase is prepared：In the 5th container, allantoin, Sodium Hyaluronate and the 1,3-BDO of formula ratio are added, with
And Part II water, 80-85 DEG C is heated to, stirring and dissolving obtains water phase；
6) emulsify：In the oil phase addition water phase, homogeneous stirs 8-12min, and sets temperature for 50-55 DEG C；
The AVC of formula ratio is subsequently adding, homogeneous stirring is thickened, when temperature reaches 50-55 DEG C,
The prefabricated solution A, homogeneous is added to stir；When cooling to 40-45 DEG C, the prefabricated solution B and prefabricated solution C, Yi Jipei are added
Phenoxyethanol, Sensiva SC50 and essence that side measures, stir, and when temperature is down to 30-35 DEG C, obtain final product the multiple face beautiful
Comfort trace face cream in vain.
5th purpose of the invention is realized using following technical scheme：
A kind of multiple-protection isolates elite, and it includes the following composition based on weight/mass percentage composition：
Main component：
Auxiliary material：
Preferably, the multiple-protection isolation elite includes the following composition based on weight/mass percentage composition：
Main component：
Auxiliary material：
6th purpose of the invention is realized using following technical scheme：
A kind of multiple-protection isolates the preparation method of elite, comprises the following steps：
1) prefabricated solution A is prepared：In the first container, the vitamin e acetate and retinyl palmitate of formula ratio are added,
Stirring and dissolving, obtains prefabricated solution A；
2) prefabricated solution B is prepared：In second container, the salicylic acid and absolute ethyl alcohol of formula ratio are added, stirring and dissolving is obtained
Prefabricated solution B；
3) prefabricated solution C is prepared：Be three parts the moisture of formula ratio, be designated as respectively Part I water, Part II water and
Part III water；In the 3rd container, 3-o- ethylascorbyls, tranexamic acid, carnosine, the kadsura longepedunculata extraction of formula ratio are added
Thing and five-leaved chaste tree extract, and Part I water, stirring and dissolving obtain prefabricated solution C；
4) prefabricated solution D is prepared：In the 4th container, the arginine of formula ratio, and Part II water are added, stirred molten
Solution, obtains prefabricated solution D；
5) oil phase is prepared：In the 5th container, ethylhexyl methoxy cinnamate, the ethylhexyl triazine of formula ratio are added
Ketone, BEMT, Uvinul A Plus and polysorbate -60, plus
To 80-85 DEG C, stirring and dissolving obtains oil phase to heat；
6) water phase is prepared：In the 6th container, the allantoin of formula ratio, Sodium Hyaluronate, 1,3-BDO and sweet are added
Oil, and Part III water, are heated to 80-85 DEG C, and stirring and dissolving adds acrylic acid (ester) class/C10-30 alkanols of formula ratio
Acrylate crosspolymers, dispersing and dissolving obtains water phase；
7) emulsify：In the oil phase addition water phase, homogeneous stirring 8-12min sets temperature for 50-55 DEG C；So
The AVC of formula ratio, homogeneous stirring thickening are added afterwards；When 50-55 DEG C of temperature arrival, plus
Enter the prefabricated solution A and prefabricated solution D, homogeneous stirs；When cooling to 40-45 DEG C, the prefabricated solution B and prefabricated solution C is added,
And the Phenoxyethanol of formula ratio, Sensiva SC50 and essence, stir, when temperature is down to 30-35 DEG C, obtain final product described
Multiple-protection isolates elite.
7th purpose of the invention is realized using following technical scheme：
A kind of net white mildy wash, it includes the following composition based on weight/mass percentage composition：
Main component：
Auxiliary material：
Preferably, the net white mildy wash includes the following composition based on weight/mass percentage composition：
Main component：
Auxiliary material：
8th purpose of the invention is realized using following technical scheme：
A kind of preparation method of net white mildy wash, comprises the following steps：
1) prefabricated solution A is prepared：In the first container, the vitamin e acetate and retinyl palmitate of formula ratio are added,
Stirring and dissolving, obtains prefabricated solution A；
2) prefabricated solution B is prepared：In second container, the salicylic acid and absolute ethyl alcohol of formula ratio are added, stirring and dissolving is obtained
Prefabricated solution B；
3) prefabricated solution C is prepared：It is two parts the moisture of formula ratio, Part I water and Part II water is designated as respectively；
In the 3rd container, 3-o- ethylascorbyls, tranexamic acid, carnosine, Fructus Schisandrae Sphenantherae extract and the five-leaved chaste tree of formula ratio is added to carry
Thing, and Part I water are taken, stirring and dissolving obtains prefabricated solution C；
4) oil phase is prepared：In the 4th container, laurate, myristic acid, stearic acid and the palmitic acid of formula ratio are added, plus
Heat of solution, obtains oil phase；
5) water phase is prepared：In the 5th container, add formula ratio allantoin, glycerine, 1,3-BDO, EDTA-2Na and
Potassium hydroxide, and Part II water, stirring and dissolving obtain water phase；
6) saponification：In the oil phase addition water phase, homogeneous, until soap group opens, stirs cooling, when temperature is down to
At 55-60 DEG C, the prefabricated solution A, prefabricated solution B and prefabricated solution C are added, stirring and dissolving when being cooled to 30-35 DEG C, is obtained final product described
Net white mildy wash.
Compared to existing technology, the beneficial effects of the present invention are：
(1) whitening provided by the present invention is dispelled scar skin care item, and altogether including 8 kinds of active components, each composition of this 8 kinds of activity can be each
From play effect, while also mutually collaboration play a role, reach make skin moisturizing, reparations, crease-resistant, whitening, dispel Huang, dispel it is red, dispel
The multiple effects such as scar.Whitening scar skin care item of dispelling can effectively repair skin barrier, promote blood microcirculation, improve the colour of skin dark
Heavy, the general phenomenon such as red, prevents the environmental stimulis such as inflammation, ultraviolet from causing melanin abnormal deposition, so that the drawbacks of forming scar,
And promote wound healing, promote the generation of the collagen, elastin laminin of skin, recover the normal physiological function of skin.
(2) whitening provided by the present invention is dispelled scar skin care item, with white-skinned face function, can reduce melanin from different approaches
Formation；Skin water loss can be prevented, skin barrier is repaired, moisturizing water lock makes skin be in the full state of a health；
The compound moisturizing water lock, can stimulate the synthesis of skin collagen while repairing skin, strengthen cell mitogen, improve
The activity of enzyme, keeps normal keratinization, improves epithelium generation；Skin can be reduced to be injured by light, mitigate skin reality
Matter light aging feature is for example coarse, wrinkle and extensive abnormal pigmentation, also improves beauty, and such as skin texture is more smooth, color and luster
More homogeneous and microgroove is reduced；Skin can be dispelled dark yellow, reply skin net white；The mutually coordinated effect of each component, can produce and dispel
Except cutaneous scars, promote skin wound healing, desalinate the effect of scar.
(3) whitening provided by the present invention is dispelled scar skin care item, can be applied to skin care, sun-proof, face cleaning as active component, be washed one's hair
Bath, etc. in all kinds of cosmetics, have wide range of applications, it is practical.
(4) whitening provided by the present invention is dispelled scar skin care item, and the working mechanism of its scar of dispelling is as follows：
1st, soften, decompose, remove, substitute aging, fibrosis non-functional scar tissue：Salicylic acid (Salicylic
Acid the degree of adhesion between keratinocyte) can be reduced, so that the Skin Cell of death is peeled off, cutin-softening layer, and
And play the role of bactericidal, prevent bacterium infection.
2nd, the ecological environment of normal skin is set up, promotes cytothesis function, promote wound healing, increase collagen
Synthesis, repairs skin barrier：Retinyl palmitate (Retinyl Palmitate)-vitamin A derivatives, can stimulate collagen
The synthesis of albumen, improves epithelium generation, keeps the normal keratinization of skin, and vitamin A can be by increasing granulation tissue shape
Promote wound healing into fibroblast mitosis is stimulated；Allantoin (Allantoin) can stimulate epithelial growth, increase
The ability of strong keratinocyte combination water, improves skin moisture-keeping power, strengthens skin barrier, allantoin collaboration Alphalin (retinol palm fibre
Glycerin monostearate), greatly strengthen the ability of skin repair；Five-leaved chaste tree extract (Vitex Negundo Extract) can stimulate day
Right DNA repair systems, activated dna reparation increases to oxidative pressure and resists and prevent cell death, increases the conjunction of protein
Into reparation skin barrier.
3rd, stimulate circulation, suppress pigment anomaly deposition, recover normal skin tone, reduce skin health state：Kadsura longepedunculata
Extract (Schisandra Sphenanthera Extract) can improve blood vessel microcirculation, suppress inflammatory factor, skin of releiving
It is the stimulation of skin tissue, rubescent, while can suppress because of melanin deposition caused by inflammation, cause color spot, scar, the colour of skin uneven；It is solidifying
Hematic acid (Tranexamic Acid) can prevent the activity of inflammatory protease (fibrinoclase), it is suppressed that blackspot portion
The confusion of the epidermal cell function of position, makes excited melanocyte return to normal condition, and the melanin for suppressing inflammation-induced sinks
Product, suppresses the pigment deposition that scar causes；3-o- ethylascorbyls (3-O-ethyl ascorbic acid), its molecule
Amount is small, and skin penetration power is good, with outstanding oxidation resistance, can remove free radical, reduces melanin, suppresses tyrosinase
Activity, prevents the generation of melanin and continues to deposit, and the black to having generated have whitening function, recovers normal skin face
Color；Carnosine (carnosine) can suppress protein-crosslinking, suppress glycosylation, and expeling skin is dark yellow, and can stimulate collagen
The synthesis of albumen, skin is dispelled dark yellow, is replied net white.
Brief description of the drawings
Fig. 1 is dispelled scar test design sketch by whitening that trace face cream is comforted in multiple face whitening that the embodiment of the present invention 1 is provided；
Fig. 2 tests design sketch by the performance of keeping humidity of the multiple-protection isolation elite that the embodiment of the present invention 2 is provided；
Fig. 3 tests design sketch by the whitening of the multiple-protection isolation elite that the embodiment of the present invention 2 is provided；
Fig. 4 tests design sketch by the whitening of the net white mildy wash of multiple-effect that the embodiment of the present invention 3 is provided.
Specific embodiment
Below, with reference to specific embodiment, the present invention is described further：
A kind of whitening is dispelled scar skin care item, including following component in percentage by weight：
As preferred scheme, the auxiliary material be water, NMF, surfactant, emollient, sun-screening agent, thickener and
One kind or any combination in preservative.
Used as preferred scheme, the NMF includes polyalcohols NMF and polysaccharide NMF；The polyalcohol
Class NMF is glycerine, two glycerine, butanediol, propane diols, dipropylene glycol, sorbierite, allantoin, PEG-4000 and PPG-
One kind or any combination in 10 methyl ethers；The polysaccharide NMF is hyaluronic acid, Sodium Hyaluronate, Propiram
One kind or any combination in the plant mucopolysaccharide NMFs such as sugar, trehalose and tamarind seed extract；The surfactant
It is Glyceryl stearate citrate, polysorbate -60 and fatty acid soaps (with laurate, myristic acid, stearic acid, palm
Acid with potassium hydroxide in and gained) in one kind or any combination；The emollient is jojoba oil, isononyl isononanoate, carbon
One kind or any in sour ethylhexyl, shea butter, vitamin e acetate, octyl group polymethyl siloxane and bisabolol
Combination；The sun-screening agent is ethylhexyl methoxy cinnamate, Uvinul T 150, double-ethyl hexyl oxy phenol anisyl
Triazine, Uvinul A Plus, butylmethoxydibenzoylmethane, the sulphur of phenyl dibenzimidazole four
Acid esters disodium, MBBT, Terephthalidene Dicamphor Sulfonic Acid, zinc oxide, titanium dioxide
One kind or any combination in titanium, octyl salicylate, Homosalate and Octocrilene；The thickener is Carbomer, propylene
One kind in sour (ester) class/C10-30 alkylol acrylamide acid esters cross-linked polymers and AVC
Or any combination；The preservative includes the one kind or any in benzoic acid, benzoate, Phenoxyethanol and Sensiva SC50
Combination.
Wherein, acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross-linked polymers (Acrylates C10-30Alkyl
Acrylate Cross Polymer) it is a kind of film forming agent, it is often used in keeping dispersing morphology to avoid condensing in water, is formed
Film can also give product provide water lock function.
AVC is also known as ammonium acryloyldime-thyltaurate/vinyl pyrrolidone
Copolymer, belongs to high molecular surfactant-acrylic polymer；Its outward appearance is in solid powder, or colourless to slightly yellow liquid
Body；Water-soluble, stabilization is degradable, with excellent emulsification, dispersion, thickening, film forming ability.
Scar skin care item are dispelled in the whitening being capable of restraining and sterilizing bacteria：Salicylic acid (Salicylic Acid) is initially sent out in willow bark
Existing, it is just used as a kind of keratolytic, is widely used in the treatment of various skin problems.Salicylic acid energy
The degree of adhesion between keratinocyte is enough reduced, so that the Skin Cell of death is peeled off, cutin-softening layer, and have sterilization
Antibacterial effect, prevents bacterium infection.
The whitening is dispelled scar skin care item, with white-skinned face function, goes to reduce the formation of melanin from different approaches：Tranexamic acid
(Tranexamic Acid) educational circles is also referred to as disconnected blood inflammation, tranxamic acid, Trenaxmine etc., belongs to fibrinolysis depressant
In a class, by the lysine-binding site on reversible plasminogen molecule, it is fibre to cause plasminogen to forward
Lyase, so as to effectively suppress fibrinolysis, produce anastalsis.Diagnosis and treatment process has been surprisingly found that the work for making skin turn white
With so in chloasma hepaticum treatment and the pharmaceutical formula label of melanin deposition.In recent years, tranexamic acid is that one kind has been obtained on skin care products
With the whitening composition of economic rights, it is a kind of protease inhibitors that clinical research for many years has proven to Trenaxmine, can prevent inflammatory
The activity of protease (fibrinoclase), it is suppressed that the confusion of the epidermal cell function at blackspot position, makes excited melanocyte
Cell returns to normal condition, suppresses the melanin deposition of inflammation-induced, can the whitening of quick-acting ground and Kohakuhi, reparation skin screen
Barrier, makes skin that pale soft and moist, bright brilliant saturating perfect skin quality is presented.
Meanwhile, 3-o- ethylascorbyls (3-O-ethyl ascorbic acid) are very wide in the application of cosmetics
Model, its molecular weight is small, skin penetration power is good, can remove free radical, reduces melanin, from and the few blackspots of Minus, reduce melanin
Precipitation, the brilliant white colour of skin.In addition, can also stimulation collagen life, recovery skin elasticity.
Scar skin care item are dispelled in the whitening being capable of moisturizing water lock, the synthesis of stimulation skin collagen：Allantoin (Allantoin)
Most early in local treatment wound is had been used to 16th century, surgeon has found that allantoin can stimulate epithelial growth, strengthens angle
Change the ability of cell combination water, improve skin moisture-keeping power, strengthen skin barrier, moisturizing is repaired because of daily life and extraneous ring simultaneously
Border pressure, stimulation, caused dry skin are damaged, and allantoin is ranged I type Derma-Guard by U.S. FDA.And cooperate with dimension
He orders A (retinyl palmitate), and the ability of its skin repair is stronger.
Whitening scar skin care item of dispelling can reduce skin and be injured by light：The long-term skin being excessively exposed under daylight
Skin, epidermis and dermal connective tissue occur slow and cumulative bad is damaged.Research is thought that only UVB radiation is harmful to skin, recently
Research shows that UVA also results in major injury.Two kinds of wavelength can cause erythema, inflammation, proteoglycan and GAG
Increase, collagen is damaged, elastic fibrosis, the final wrinkle of skin that increases increases, and skin elasticity declines, skin senescence.The present invention
Compound in contain vitamin A derivatives, retinyl palmitate (Retinyl Palmitate), many controls are faced
Bed research have rated effect of the vitamin A to people's photoaging skin.Vitamin A not only mitigates skin substance light aging feature
Such as coarse, wrinkle and extensive abnormal pigmentation, also improve beauty, such as skin texture is more smooth, color and luster is more homogeneous and microgroove subtracts
It is few.
The whitening is dispelled, and can to dispel skin dark yellow for scar skin care item, replys skin net white：With age, glucose is not
Disconnected and protein binding, can form AGEs (candy base dead end product), and candy baseization can cause protein-crosslinking, cell to lose splitting ability
It is one of artifacts of candy base.Skin gradually shows as brown color, and toughness reduction, and this process is referred to as Mei Lade
Reaction.Carnosine (carnosine) natural equivalent is present in the alanyl-L-Histidine in human body, can suppress protein-crosslinking,
Suppress glycosylation, drive away that skin is dark yellow, and can stimulation collagen synthesis, skin is dispelled dark yellow, is replied net white.
Whitening scar skin care item of dispelling can suppress rubescent：Fructus Schisandrae Sphenantherae extract (Schisandra Sphenanthera
Extract) the schisandra chinensis wild acinus collected in 3000 meters of eminences of height above sea level, the outward appearance of berry is similar with blackcurrant, passes through
The extract that the continuable extraction process of green is obtained.Suppress inflammatory factor, reduce capilary diastole, improve microcirculation, prevent
The formation of red blood silk, dispels rubefaction.
A kind of whitening is dispelled the preparation method of scar skin care item, when the auxiliary material is water, is comprised the following steps：
1) A phases are prepared：At normal temperatures, by the 3-o- ethylascorbyls of formula ratio, allantoin, tranexamic acid, carnosine, south five
Taste seed extract and five-leaved chaste tree extract are placed in the first container, are subsequently adding the water of formula ratio, and stirring and dissolving obtains A phases；
2) B phases are prepared：At normal temperatures, the retinyl palmitate and salicylic acid of formula ratio are placed in second container, so
The ethanol of formula ratio is added afterwards, and stirring and dissolving obtains B phases；
3) mix：The temperature of A phases and B phases is adjusted to 25-35 DEG C, is then mixed, stirred, obtained final product.
Embodiment 1
Trace face cream, including following component in percentage by weight are comforted in a kind of multiple face whitening：
Main component：
Auxiliary material：
The preparation method that trace face cream is comforted in above-mentioned multiple face whitening is comprised the following steps successively：
1) prefabricated solution A is prepared：In the first container, vitamin e acetate, bisabolol and the retinol of formula ratio are added
Palmitate, stirring and dissolving obtains prefabricated solution A；
2) prefabricated solution B is prepared：In second container, the salicylic acid and absolute ethyl alcohol of formula ratio are added, stirring and dissolving is obtained
Prefabricated solution B；
3) prefabricated solution C is prepared：It is two parts the moisture of formula ratio, Part I water and Part II water is designated as respectively；
In the 3rd container, 3-o- ethylascorbyls, tranexamic acid, carnosine, Fructus Schisandrae Sphenantherae extract and the five-leaved chaste tree of formula ratio is added to carry
Thing, and Part I water are taken, stirring and dissolving obtains prefabricated solution C；
4) oil phase is prepared：In the 4th container, jojoba oil, isononyl isononanoate, the carbonic acid diethyl of formula ratio are added
Own ester, shea butter, octyl group polymethyl siloxane and Glyceryl stearate citrate, are heated to 80-85 DEG C, stirring and dissolving,
Obtain oil phase；
5) water phase is prepared：In the 5th container, allantoin, Sodium Hyaluronate and the 1,3-BDO of formula ratio are added, with
And Part II water, 80-85 DEG C is heated to, stirring and dissolving obtains water phase；
6) emulsify：In the oil phase addition water phase, homogeneous stirs 8-12min, and sets temperature for 50-55 DEG C；
The AVC of formula ratio is subsequently adding, homogeneous stirring is thickened, when temperature reaches 50-55 DEG C,
The prefabricated solution A, homogeneous is added to stir；When cooling to 40-45 DEG C, the prefabricated solution B and prefabricated solution C, Yi Jipei are added
Phenoxyethanol, Sensiva SC50 and essence that side measures, stir, and when temperature is down to 30-35 DEG C, obtain final product the multiple face beautiful
Comfort trace face cream in vain.
Test case 1
Whitening is dispelled scar method of testing：
Experimental principle：Using human body skinanalysis apparatus MAP580, before and after using product by testing volunteer, skin at scar
Whitening of the variable quantity of skin melanin to assess product is dispelled scar effect.
Experimental subjects：6 triers, arm has obvious scar, wherein 4 males, 2 women, the age is 25-35 year
Between.
Experimental technique：Arm scar fix region, using same amount embodiment 1 acquired in multiple face whitening comfort
Trace face cream, consumption is all 2mg/cm2, Morning Afternoon Evening is used 3 times daily, continuous to use 28 days, is surveyed using human body skin tester
Examination volunteer the 0th day, the 7th day, the 14th day, the 21st day, the 28th day scarred skin melanin content and blank dermal melanin
Content, and averaging, the whitening for assessing product is dispelled scar effect.Test effect see the table below 1, meanwhile, provide test effect curve
Figure, is shown in accompanying drawing 1.
The scar effect recording table of dispelling of trace face cream is comforted in the multiple face whitening of 1 embodiment of table 1
From upper table 1 and accompanying drawing 1 as can be seen that the multiple face whitening that continuous embodiment 1 on probation is provided comforts trace face cream 28 days, can
The melanin content of skin at scar is reduced, makes skin reply the normal colour of skin of health, to eliminating scar pigment, skin whitening has
Obvious effect.
Embodiment 2
A kind of multiple-protection isolates elite, including following component in percentage by weight：
Main component：
Auxiliary material：
The preparation method of above-mentioned multiple-protection isolation elite is comprised the following steps successively：
1) prefabricated solution A is prepared：In the first container, the vitamin e acetate and retinyl palmitate of formula ratio are added,
Stirring and dissolving, obtains prefabricated solution A；
2) prefabricated solution B is prepared：In second container, the salicylic acid and absolute ethyl alcohol of formula ratio are added, stirring and dissolving is obtained
Prefabricated solution B；
3) prefabricated solution C is prepared：Be three parts the moisture of formula ratio, be designated as respectively Part I water, Part II water and
Part III water；In the 3rd container, 3-o- ethylascorbyls, tranexamic acid, carnosine, the kadsura longepedunculata extraction of formula ratio are added
Thing and five-leaved chaste tree extract, and Part I water, stirring and dissolving obtain prefabricated solution C；
4) prefabricated solution D is prepared：In the 4th container, the arginine of formula ratio, and Part II water are added, stirred molten
Solution, obtains prefabricated solution D；
5) oil phase is prepared：In the 5th container, ethylhexyl methoxy cinnamate, the ethylhexyl triazine of formula ratio are added
Ketone, BEMT, Uvinul A Plus and polysorbate -60, plus
To 80-85 DEG C, stirring and dissolving obtains oil phase to heat；
6) water phase is prepared：In the 6th container, the allantoin of formula ratio, Sodium Hyaluronate, 1,3-BDO and sweet are added
Oil, and Part III water, are heated to 80-85 DEG C, and stirring and dissolving adds acrylic acid (ester) class/C10-30 alkanols of formula ratio
Acrylate crosspolymers, dispersing and dissolving obtains water phase；
7) emulsify：In the oil phase addition water phase, homogeneous stirring 8-12min sets temperature for 50-55 DEG C；So
The AVC of formula ratio, homogeneous stirring thickening are added afterwards；When 50-55 DEG C of temperature arrival, plus
Enter the prefabricated solution A and prefabricated solution D, homogeneous stirs；When cooling to 40-45 DEG C, the prefabricated solution B and prefabricated solution C is added,
And the Phenoxyethanol of formula ratio, Sensiva SC50 and essence, stir, when temperature is down to 30-35 DEG C, obtain final product described
Multiple-protection isolates elite.
Test case 2
1st, sun-proof test：
Using the sun-proof of the multiple-protection isolation elite acquired in SPF tester (SPF-290S) testing example 2
Ability, be skin support anti-ultraviolet injury, prevent sunburn, it is tanned, prevent skin photoage, prevent the injury due to ultraviolet
And the dry skin that causes is obscure.Multiple-protection isolation elite (in vitro) test result is SPF 32, PA+++.
2nd, moisture of skin barrier test：
Test philosophy：Using human body skinanalysis apparatus MAP580, by testing volunteer using before and after product, skin is aqueous
The moisture-retaining capacity of product is assessed in the change of amount.
Experimental technique：20 volunteers are chosen, the age, the region fixed in two inboard arms used between 25-35 Sui
Multiple-protection isolation elite acquired in the embodiment 2 of same amount, consumption is all 2mg/cm2, using human body skin tester
To test skin moisture content of the volunteer before and after, and average, assess the performance of keeping humidity of product.Test result is as follows
Shown in table 2, meanwhile, the test design sketch of performance of keeping humidity is given, see accompanying drawing 2.
The multiple-protection of 2 embodiment of table 2 isolates the moistening effect record sheet of elite
Be can be seen that from upper table 2 and accompanying drawing 2, the multiple-protection provided using embodiment 2 isolates elite can increase skin
Skin moisture, so as to increase skin barrier ability, makes skin be in a physiological status for health.
3rd, whitening test：
Test philosophy：Using human body skinanalysis apparatus MAP580, before and after using product by testing volunteer, skin black
The variable quantity of element assesses the white-skinned face function of product.
Experimental technique：20 volunteers are chosen, the age between 25-35 Sui, in the region that two inboard arms are fixed, uses
The multiple-protection isolation elite that the embodiment 2 of same amount is provided, consumption is all 2mg/cm2, Morning Afternoon Evening daily use 3 times,
It is continuous to use 28 days, volunteer is tested using human body skin tester the 0th day, the 7th day, the 14th day, the 21st day, the 28th day skin
Skin melanin content and blank dermal melanin content, and average, assess the white-skinned face function of product.Test result sees below
Table 3.
The multiple-protection of 3 embodiment of table 2 isolates the whitening effect record sheet of elite
Data according to the gained of table 3 are further processed, and calculate volunteer and continuously use 28 days, the 7th day, the 14th
My god, the 21st day, the decrement of the 28th day dermal melanin, obtain table 4 below data:
The melanin decrement record sheet of table 4
Data according to the gained of table 4 are further processed, and calculate volunteer and continuously use 28 days, the 7th day, the 14th
My god, the 21st day, the slip of the 28th day dermal melanin, obtain the data of table 5 below, and draw corresponding chart, see accompanying drawing 3.
The melanin slip record sheet of table 5
The multiple-protection that can be seen that continuous embodiment 2 on probation from table 3-5 and Fig. 3 isolates elite 28 days, skin black
Plain slip is up to 24.8%, the brilliant white colour of skin.
Embodiment 3
A kind of net white mildy wash of multiple-effect, including following component in percentage by weight：
Main component：
Auxiliary material：
The preparation method of the net white mildy wash of above-mentioned multiple-effect is comprised the following steps successively：
1) prefabricated solution A is prepared：In the first container, the vitamin e acetate and retinyl palmitate of formula ratio are added,
Stirring and dissolving, obtains prefabricated solution A；
2) prefabricated solution B is prepared：In second container, the salicylic acid and absolute ethyl alcohol of formula ratio are added, stirring and dissolving is obtained
Prefabricated solution B；
3) prefabricated solution C is prepared：It is two parts the moisture of formula ratio, Part I water and Part II water is designated as respectively；
In the 3rd container, 3-o- ethylascorbyls, tranexamic acid, carnosine, Fructus Schisandrae Sphenantherae extract and the five-leaved chaste tree of formula ratio is added to carry
Thing, and Part I water are taken, stirring and dissolving obtains prefabricated solution C；
4) oil phase is prepared：In the 4th container, laurate, myristic acid, stearic acid and the palmitic acid of formula ratio are added, plus
Heat of solution, obtains oil phase；
5) water phase is prepared：In the 5th container, add formula ratio allantoin, glycerine, 1,3-BDO, EDTA-2Na and
Potassium hydroxide, and Part II water, stirring and dissolving obtain water phase；
6) saponification：In the oil phase addition water phase, homogeneous, until soap group opens, stirs cooling, when temperature is down to
At 55-60 DEG C, the prefabricated solution A, prefabricated solution B and prefabricated solution C are added, stirring and dissolving when being cooled to 30-35 DEG C, is obtained final product described
Net white mildy wash.
Test case 3
Whitening is tested：
Test philosophy：Using human body skinanalysis apparatus MAP580, before and after using product by testing volunteer, skin black
Element variable quantity come assess product net contour painting imitate.
Experimental technique：20 volunteers are chosen, the age, test volunteer used the net white of embodiment 3 between 25-35 Sui
Before and after mildy wash cleaning face, the change of facial skin melanin content is tested, and the instant net of net white mildy wash is assessed with this
White effect, is specifically shown in accompanying drawing 4.
From fig. 4, it can be seen that after using the net white mildy wash of multiple-effect, dermal melanin is significantly reduced, and net white effect is notable.
It will be apparent to those skilled in the art that technical scheme that can be as described above and design, make other various
It is corresponding to change and deformation, and all these change and deformation should all belong to the protection domain of the claims in the present invention
Within.
Claims (10)
1. a kind of whitening is dispelled scar skin care item, it is characterised in that including following component in percentage by weight：
2. whitening according to claim 1 is dispelled scar skin care item, it is characterised in that the auxiliary material is that water, NMF, surface are lived
One kind or any combination in property agent, emollient, sun-screening agent, thickener and preservative.
3. whitening according to claim 2 is dispelled scar skin care item, it is characterised in that the NMF includes polyalcohols moisturizing
Agent and polysaccharide NMF；
The polyalcohols NMF is glycerine, two glycerine, butanediol, propane diols, dipropylene glycol, sorbierite, allantoin, poly- second
One kind or any combination in glycol -400 and PPG-10 methyl ethers；
The polysaccharide NMF is in hyaluronic acid, Sodium Hyaluronate, pulullan, trehalose and tamarind seed extract
Plant or be combined；
The surfactant is for the one kind in Glyceryl stearate citrate, polysorbate -60 and fatty acid soaps or appoints
Meaning combination；
The emollient be jojoba oil, isononyl isononanoate, diethyl hexylcarbonate, shea butter, vitamin e acetate,
One kind or any combination in octyl group polymethyl siloxane and bisabolol；
The sun-screening agent is ethylhexyl methoxy cinnamate, Uvinul T 150, double-ethyl hexyl oxy phenol anisyl three
Piperazine, Uvinul A Plus, butylmethoxydibenzoylmethane, phenyl dibenzimidazole tetrasulfonic acid
Ester disodium, MBBT, Terephthalidene Dicamphor Sulfonic Acid, zinc oxide, titanium dioxide
One kind or any combination in titanium, octyl salicylate, Homosalate and Octocrilene；
The thickener is Carbomer, acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross-linked polymers and acryloyl diformazan
One kind or any combination in base taurine ammonium/VP copolymers；
The preservative includes the one kind or any combination in benzoic acid, benzoate, Phenoxyethanol and Sensiva SC50.
4. a kind of whitening as claimed in claim 1 is dispelled the preparation method of scar skin care item, it is characterised in that when the auxiliary material is water
When, comprise the following steps：
1) A phases are prepared：At normal temperatures, by 3-o- ethylascorbyls, allantoin, tranexamic acid, carnosine, the kadsura longepedunculata of formula ratio
Extract and five-leaved chaste tree extract are placed in the first container, are subsequently adding the water of formula ratio, and stirring and dissolving obtains A phases；
2) B phases are prepared：At normal temperatures, the retinyl palmitate and salicylic acid of formula ratio are placed in second container, Ran Houjia
Enter the ethanol of formula ratio, stirring and dissolving obtains B phases；
3) mix：The temperature of A phases and B phases is adjusted to 25-35 DEG C, is then mixed, stirred, obtained final product.
5. whitening according to claim 1 is dispelled scar skin care item, it is characterised in that the cosmetics are comforted for a kind of multiple face whitening
Trace face cream, it includes the following composition based on weight/mass percentage composition：
Main component：
Auxiliary material：
6. the preparation method of trace face cream is comforted in a kind of face whitening again as claimed in claim 5, it is characterised in that including following step
Suddenly：
1) prefabricated solution A is prepared：In the first container, vitamin e acetate, bisabolol and the retinol palm of formula ratio are added
Acid esters, stirring and dissolving obtains prefabricated solution A；
2) prefabricated solution B is prepared：In second container, the salicylic acid and absolute ethyl alcohol of formula ratio are added, stirring and dissolving is obtained prefabricated
Liquid B；
3) prefabricated solution C is prepared：It is two parts the moisture of formula ratio, Part I water and Part II water is designated as respectively；
In three containers, 3-o- ethylascorbyls, tranexamic acid, carnosine, Fructus Schisandrae Sphenantherae extract and the five-leaved chaste tree extract of formula ratio are added,
And Part I water, stirring and dissolving, obtain prefabricated solution C；
4) oil phase is prepared：In the 4th container, add the jojoba oil of formula ratio, isononyl isononanoate, diethyl hexylcarbonate,
Shea butter, octyl group polymethyl siloxane and Glyceryl stearate citrate, are heated to 80-85 DEG C, and stirring and dissolving obtains oil
Phase；
5) water phase is prepared：In the 5th container, allantoin, Sodium Hyaluronate and the 1,3-BDO of formula ratio, Yi Ji are added
Two part water, are heated to 80-85 DEG C, and stirring and dissolving obtains water phase；
6) emulsify：In the oil phase addition water phase, homogeneous stirs 8-12min, and sets temperature for 50-55 DEG C；Then
The AVC of formula ratio is added, homogeneous stirring thickening, when temperature reaches 50-55 DEG C, is added
The prefabricated solution A, homogeneous stirs；When cooling to 40-45 DEG C, the prefabricated solution B and prefabricated solution C, and formula ratio are added
Phenoxyethanol, Sensiva SC50 and essence, stir, when temperature is down to 30-35 DEG C, obtains final product the multiple face whitening and comfort
Trace face cream.
7. whitening according to claim 1 is dispelled scar skin care item, it is characterised in that the cosmetics be a kind of multiple-protection every
From elite, it includes the following composition based on weight/mass percentage composition：
Main component：
Auxiliary material：
8. a kind of multiple-protection as claimed in claim 7 isolates the preparation method of elite, it is characterised in that including following step
Suddenly：
1) prefabricated solution A is prepared：In the first container, the vitamin e acetate and retinyl palmitate of formula ratio, stirring are added
Dissolving, obtains prefabricated solution A；
2) prefabricated solution B is prepared：In second container, the salicylic acid and absolute ethyl alcohol of formula ratio are added, stirring and dissolving is obtained prefabricated
Liquid B；
3) prefabricated solution C is prepared：It is three parts the moisture of formula ratio, Part I water, Part II water and the 3rd is designated as respectively
Part water；In the 3rd container, add the 3-o- ethylascorbyls of formula ratio, tranexamic acid, carnosine, Fructus Schisandrae Sphenantherae extract and
Five-leaved chaste tree extract, and Part I water, stirring and dissolving obtain prefabricated solution C；
4) prefabricated solution D is prepared：In the 4th container, the arginine of formula ratio, and Part II water, stirring and dissolving are added, obtained
Obtain prefabricated solution D；
5) oil phase is prepared：In the 5th container, add the ethylhexyl methoxy cinnamate of formula ratio, Uvinul T 150,
BEMT, Uvinul A Plus and polysorbate -60, heating
To 80-85 DEG C, stirring and dissolving obtains oil phase；
6) water phase is prepared：In the 6th container, allantoin, Sodium Hyaluronate, 1,3-BDO and the glycerine of formula ratio are added, with
And Part III water, 80-85 DEG C is heated to, stirring and dissolving adds acrylic acid (ester) class/C10-30 alkylol acrylamides acid of formula ratio
Ester cross-linked polymer, dispersing and dissolving obtains water phase；
7) emulsify：In the oil phase addition water phase, homogeneous stirring 8-12min sets temperature for 50-55 DEG C；Then plus
Enter the AVC of formula ratio, homogeneous stirring thickening；When temperature reaches 50-55 DEG C, institute is added
Prefabricated solution A and prefabricated solution D is stated, homogeneous stirs；When cooling to 40-45 DEG C, the prefabricated solution B and prefabricated solution C is added, and
The Phenoxyethanol of formula ratio, Sensiva SC50 and essence, stir, and when temperature is down to 30-35 DEG C, obtain final product described multiple
Protection isolation elite.
9. whitening according to claim 1 is dispelled scar skin care item, it is characterised in that the cosmetics are a kind of net white face cleaning
Breast, it includes the following composition based on weight/mass percentage composition：
Main component：
Auxiliary material：
10. a kind of preparation method of mildy wash as claimed in claim 9 net white, it is characterised in that comprise the following steps：
1) prefabricated solution A is prepared：In the first container, the vitamin e acetate and retinyl palmitate of formula ratio, stirring are added
Dissolving, obtains prefabricated solution A；
2) prefabricated solution B is prepared：In second container, the salicylic acid and absolute ethyl alcohol of formula ratio are added, stirring and dissolving is obtained prefabricated
Liquid B；
3) prefabricated solution C is prepared：It is two parts the moisture of formula ratio, Part I water and Part II water is designated as respectively；
In three containers, 3-o- ethylascorbyls, tranexamic acid, carnosine, Fructus Schisandrae Sphenantherae extract and the five-leaved chaste tree extract of formula ratio are added,
And Part I water, stirring and dissolving, obtain prefabricated solution C；
4) oil phase is prepared：In the 4th container, laurate, myristic acid, stearic acid and the palmitic acid of formula ratio are added, heated molten
Solution, obtains oil phase；
5) water phase is prepared：In the 5th container, allantoin, the glycerine of formula ratio, 1,3-BDO, EDTA-2Na and hydrogen-oxygen are added
Change potassium, and Part II water, stirring and dissolving obtains water phase；
6) saponification：In the oil phase addition water phase, homogeneous, until soap group opens, stirs cooling, when temperature is down to 55-
At 60 DEG C, the prefabricated solution A, prefabricated solution B and prefabricated solution C are added, stirring and dissolving when being cooled to 30-35 DEG C, is obtained final product described net white
Mildy wash.
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| CN107441034A (en) * | 2017-09-18 | 2017-12-08 | 广州赛莱拉干细胞科技股份有限公司 | A kind of whitening cosmetics containing five-leaved chaste tree stem cell and preparation method thereof |
| CN109010181A (en) * | 2018-09-26 | 2018-12-18 | 谢佳妤 | A kind of formula of skin care item |
| CN109010195A (en) * | 2018-10-13 | 2018-12-18 | 陈洁珍 | A kind of whitening Wrinkle-and scar-removing repairs face cream and preparation method thereof |
| CN109106681A (en) * | 2018-09-28 | 2019-01-01 | 广东芭薇生物科技股份有限公司 | Micro- solidifying pearl cleawhite over-night essences of one kind and preparation method thereof |
| CN109288781A (en) * | 2018-09-03 | 2019-02-01 | 芜湖凌梦电子商务有限公司 | Whitening and softening skin essence cream and preparation method thereof |
| CN111265463A (en) * | 2020-04-10 | 2020-06-12 | 上海新高姿化妆品有限公司 | Anti-aging cosmetic composition for whitening and brightening skin |
| CN114617787A (en) * | 2021-11-30 | 2022-06-14 | 上海优萃生物科技有限公司 | High-stability composition for protecting whitening agent and application thereof |
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| CN109106681A (en) * | 2018-09-28 | 2019-01-01 | 广东芭薇生物科技股份有限公司 | Micro- solidifying pearl cleawhite over-night essences of one kind and preparation method thereof |
| CN109106681B (en) * | 2018-09-28 | 2021-08-27 | 广东芭薇生物科技股份有限公司 | Micro-bead whitening essence and preparation method thereof |
| CN109010195A (en) * | 2018-10-13 | 2018-12-18 | 陈洁珍 | A kind of whitening Wrinkle-and scar-removing repairs face cream and preparation method thereof |
| CN111265463A (en) * | 2020-04-10 | 2020-06-12 | 上海新高姿化妆品有限公司 | Anti-aging cosmetic composition for whitening and brightening skin |
| CN114617787A (en) * | 2021-11-30 | 2022-06-14 | 上海优萃生物科技有限公司 | High-stability composition for protecting whitening agent and application thereof |
| CN114617787B (en) * | 2021-11-30 | 2023-10-13 | 上海优萃生物科技有限公司 | High-stability composition for protecting whitening agent and application thereof |
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