CN106853149A - 一种可有效治疗肾阳虚衰及气虚血亏的新型中药组合物 - Google Patents

一种可有效治疗肾阳虚衰及气虚血亏的新型中药组合物 Download PDF

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CN106853149A
CN106853149A CN201710085619.0A CN201710085619A CN106853149A CN 106853149 A CN106853149 A CN 106853149A CN 201710085619 A CN201710085619 A CN 201710085619A CN 106853149 A CN106853149 A CN 106853149A
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kidney
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罗兴兰
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Sichuan Shuangxin Biological Technology Co Ltd
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Abstract

本发明属于中药制剂领域,目的是根据中医治疗肾阳虚衰及气虚血亏的认识机理而提供的一种可有效治疗肾阳虚衰及气虚血亏的新型中药组合物,所述中药组合物的各个组分及其质量份比如下:人参95g、杜仲140g、枸杞子190g、肉桂80g、山药270g、淫羊藿80g、锁阳120g、茯苓230g、肉苁蓉120g、附子70g、牡丹皮95g、菟丝子120g、熟地黄280g、山茱萸95g、泽泻120g、仙茅80g、韭菜子80g、黄芪280g、当归120g、鹿鞭120g、鱼鳔280g、五味子50g、牛膝140g、海龙95g、海马95g、蛤蚧60g、阿胶120g、龟甲胶80g、冬虫夏草95g、车前子140g;本发明提供的药物是一个很好的中药组方。

Description

一种可有效治疗肾阳虚衰及气虚血亏的新型中药组合物
技术领域
本发明属于中药制剂领域,具体涉及一种可有效治疗肾阳虚衰及气虚血亏的新型中药组合物,特别是供肾阳虚衰及气虚血亏患者使用的新型中药组合物的领域。
背景技术
肾阳虚为中医名词术语。由于肾阳虚衰,温煦失职,气化失权所表现的一类虚寒证候,称为肾阳虚证。多由素体阳虚,或年老肾亏,或久病伤肾,以及房劳过度等因素引起的。
中医又认为,肾主水,肾阳对水液有气化蒸腾作用,若肾阳不足,蒸腾气化无力,则出现小便清长等表现,故肾阳虚证存在着肾脏的病理改变。肾虚多为长期积累成疾,切不可以急于求成而用大补之药进补,或者用成份不明的补肾壮阳药物,而应慢慢调理。肾阳亦称为元阳、真阳、真火,十二经之根,先天之本在于肾。肾与命门本同一气,为人身阴阳消长之枢纽。肾阳主一身之阳气,火衰其本则阳虚之证迭出。
肾阳虚与现代医学的神经内分泌免疫系统(NEIS)有关,肾阳虚证在下丘脑-垂体-靶腺(肾上腺皮质、甲状腺、性腺、胸腺)轴均有不同环节、不同程度的功能紊乱,且主要的发病环节在下丘脑(或更高级中枢)的调节功能紊乱。
气虚,为中医名词术语。是指由于元气不足引起的一系列病理变化及证候。所谓气,是人体最基本的物质,由肾中的精气、脾胃吸收运化水谷之气和肺吸入的清气共同结合而成。气虚,泛指身体虚弱、面色苍白、呼吸短促、四肢乏力、头晕、动则汗出、语声低微等。包括元气、宗气、卫气的虚损,以及气的推动、温煦、防御、固摄和气化功能的减退,从而导致机体的某些功能活动低下或衰退,抗病能力下降等衰弱的现象。人的生命活动从根本上讲,就是元气升降出入的运动。气虚是一种多发证,多因先天不足、营养不良、年老虚弱、久病未愈、手术后及疲劳过度。在临床上,气虚还包括肺气虚、心气虚、脾气虚、肾气虚诸证。
血亏,指血液亏虚,脏腑、经络、形体失养,以面色淡白或萎黄,唇舌爪甲色淡,头晕眼花,心悸多梦,手足发麻,妇女月经量少、色淡、后期或经闭,脉细等为常见证候。
那么,就如何找到一种可有效治疗肾阳虚衰及气虚血亏的中药组合物,是本领域技术人员亟待要解决的问题。
发明内容
随着我国中医中药学的不断发展,在治疗肾阳虚衰及气虚血亏上,人们逐渐意识到了中医治疗肾阳虚衰及气虚血亏的优点,且在治疗过程中疗效好、见效快、毒副作用小等优势,针对现有西医治疗肾阳虚衰及气虚血亏的现状,本发明的目的是在于提供一种可有效治疗肾阳虚衰及气虚血亏的新型中药组合物,以解决肾阳虚衰及气虚血亏患者早日恢复健康的问题。该药物是以常见的中药为原料,通过选择合理的药物及质量份比,可有效治疗上述肾阳虚衰及气虚血亏。
为达到上述发明的目的,本发明所采用的技术方案为:提供一种可有效治疗肾阳虚衰及气虚血亏的新型中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
人参30~120g、杜仲60~180g、枸杞子100~250g、肉桂30~100g、山药150~350g、淫羊藿30~100g、锁阳50~160g、茯苓150~300g、肉苁蓉100~160g、附子30~90g、牡丹皮60~120g、菟丝子60~160g、熟地黄100~380g、山茱萸50~120g、泽泻60~160g、仙茅30~100g、韭菜子30~100g、黄芪150~350g、当归80~160g、鹿鞭60~160g、鱼鳔100~350g、五味子30~70g、牛膝50~180g、海龙30~120g、海马30~120g、蛤蚧30~80g、阿胶50~160g、龟甲胶30~100g、冬虫夏草50~120g、车前子100~180g。
一种可有效治疗肾阳虚衰及气虚血亏的新型中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
人参38~105g、杜仲70~160g、枸杞子115~220g、肉桂38~90g、山药170~310g、淫羊藿38~90g、锁阳60~140g、茯苓170~260g、肉苁蓉115~140g、附子38~80g、牡丹皮70~105g、菟丝子70~140g、熟地黄115~320g、山茱萸60~105g、泽泻70~140g、仙茅38~90g、韭菜子38~90g、黄芪180~310g、当归90~140g、鹿鞭70~140g、鱼鳔115~310g、五味子38~60g、牛膝60~160g、海龙38~105g、海马38~105g、蛤蚧38~70g、阿胶60~140g、龟甲胶38~90g、冬虫夏草58~105g、车前子115~160g。
一种可有效治疗肾阳虚衰及气虚血亏的新型中药组合物,其特征在于,所述“最佳方案”的中药组合物的各个组分及其质量份比如下所示:
人参95g、杜仲140g、枸杞子190g、肉桂80g、山药270g、淫羊藿80g、锁阳120g、茯苓230g、肉苁蓉120g、附子70g、牡丹皮95g、菟丝子120g、熟地黄280g、山茱萸95g、泽泻120g、仙茅80g、韭菜子80g、黄芪280g、当归120g、鹿鞭120g、鱼鳔280g、五味子50g、牛膝140g、海龙95g、海马95g、蛤蚧60g、阿胶120g、龟甲胶80g、冬虫夏草95g、车前子140g。
一种可有效治疗肾阳虚衰及气虚血亏的新型中药组合物,其特征在于,所述方法包括如下步骤制备而成:
A、将上述原料中药拣去杂质、粉尘及干燥后,按照质量份比共研为极细末待用;
B、按照传统的常规工艺及辅料制备中药胶囊剂的方法,将研磨好的极细末药物过筛后,和辅料一并放入药器中混合均匀,然后制备成胶囊剂(其胶囊锁合后总长度为23.3mm,药粉容量0.4~0.5g/粒),进而消毒、分装,密封即可。
一种可有效治疗肾阳虚衰及气虚血亏的新型中药组合物,其特征在于,所述服用方法为:将制备好的胶囊剂药物以每日三次服用,早中晚各服一次,给药量2.5g(5粒)/次,温开水送服。服药21~35天,症状逐渐消失,并痊愈。
本发明组方中的各原料中药在中国药典、中国辞典以及中华本草中均有详细的记载。本发明选用其中最常见的中药为原料,充分发挥各组分的药理功效:
人参,性味:味苦、微苦、性微温,具有大补元气、补脾益肺、生津止渴、安神益短之功效,用于治疗劳伤虚损、食少、倦怠、反胃吐食、大便滑泄、虚咳喘促、自汗暴脱、惊悸、健忘、眩晕头痛、阳萎、尿频、消渴、妇女崩漏、小儿慢惊、久虚不复、气血津液不足之证等症;
杜仲,性味:甘、微辛、性温,具有补肝肾、强筋骨、安胎之功效,用于治疗腰脊酸疼、阳痿、尿频、小便余沥、风湿痹痛、胎动不安、习惯性流产等症;
枸杞子,性味:味甘、性平,具有养肝、滋肾、润肺之功效,用于治疗肝肾亏虚、头晕目眩、目视一清、腰膝酸软、阳痿贵精、虚劳咳嗽、消渴引饮等症;
肉桂,性味:辛、甘、热,具有补火助阳、引火归源、散寒止痛、温经通脉之功效,用于治疗肾阳不足、命门火畏寒肢冷、腰膝酸软、阳痿遗精、小便不利或频数、短气喘促、浮肿尿少诸证、命门火衰、火不归源、戴阳、格阳、及上热下寒、面赤足冷、头晕耳鸣、口舌糜破、脾肾虚寒、脘腹冷痛、食减便溏、肾虚腰痛、寒湿痹痛、寒疝疼痛、宫冷不孕、痛经经闭、产后瘀滞腹痛、阴疽流注或虚寒痈疡脓成不溃或溃后不敛等;
山药,性味:甘、平,具有补脾、养肺、固肾、益精之功效,用于治疗脾虚泄泻、食少浮肿、肺虚咳喘、消渴、遗精、带下、肾虚尿频,外用治痈肿、瘰疬等症;
淫羊藿,性味:味辛,甘,性温,具有补肾壮阳,祛风除湿,强筋键骨之功效,用于治疗阳痿遗精,虚冷不育,尿频失楚,肾虚喘咳,腰膝酸软,风湿痹痛,半身不遂,四肢不仁等症;
锁阳,性味:味甘、性温,具有补肾壮阳、益肠通便之功效,用于治疗肾虚阳痿、遗精早泄、下肢痿软、虚人便秘等症;
茯苓,性味:甘、淡、平,具有渗湿利水、健脾和胃、宁心安神之功效,用于治疗小便不利、水肿胀满、痰饮咳逆、呕吐、脾虚食少、泄泻、心悸不安、失眠健忘、遗精白浊;
肉苁蓉,性味:味甘、咸、性温,具有补肾阳、益精血、润肠道之功效,用于治疗肾阳虚衰、精血不足之阳痿、遗精、白浊、尿频余沥、腰痛脚弱、耳鸣目花、月经衍期、宫寒不孕、肠燥便秘;
附子,性味:辛、甘、性热,有毒,具有回阳救逆、补火助阳、散寒除湿之功效,用于治疗亡阳欲脱、肢冷脉微、阳痿宫冷、心腹冷痛、虚寒吐泻久痢、阴寒水肿、阳虚外感、风寒湿痹、阴疽疮疡;
牡丹皮,性味:辛苦、凉、微寒,具有清热、活血散瘀之功效,用于治疗温热病热入血分、发斑、吐衄、热泪盈眶病菌后期热伏阴分发热、阴虚骨蒸潮热、血滞经闭、痛经、痈肿疮毒、跌扑伤痛、风湿热痹;
菟丝子,性味:辛甘、平,具有补肾益精、养肝明目、固胎止泄之功效,用于治疗腰膝酸痛、遗精、阳痿、早泄、不育、消渴、淋浊、遗尿、目昏耳鸣、胎动不安、流产、泄泻等症;
熟地黄,性味:味甘、性温,具有补血滋润、益精填髓之功效,用于治疗血虎萎黄、眩晕心悸、月经不调、崩不止、肝肾阴亏、潮热盗汗、遗精阳痿、不育不孕、腰膝酸软、耳鸣耳聋、头目昏花、须发早白、消渴、便秘、肾虚喘促等症;
山茱萸,性味:味酸、性微温,具有补益肝肾、收敛固脱之功效,用于治疗腰头晕目眩、耳聋耳鸣、腰膝酸软、跹精滑精、小便频数、虚汗不止、妇女崩漏等症;
泽泻,性味:味甘、淡、性寒,具有利水渗湿、泄热通淋之功效,用于治疗小便不利、热淋涩痛、水肿胀满、泄泻、痰饮眩晕、遗精等症;
仙茅,性味:辛、温,有毒,具有温肾阳壮、祛除寒湿之功效,用于治疗阳萎精冷、小便失禁、脘腹冷痛、腰膝酸痛、筋骨软弱、下肢拘挛、更年期综合征等症;
韭菜子,性味:辛、甘、温,具有温补肝肾、壮阳固精之功效,用于治疗阳痿遗精、腰膝酸痛、遗尿尿频、白浊带下等症;
黄芪,性味:甘、微温,具有补齐固表、托疮生肌之功效,用于治疗体虚自汗、久泻、脱肛、子宫脱垂、慢性肾炎、体虚浮肿、慢性溃疡、疮口久不愈合等症;
当归,性味:性温、味甘辛, 具有补血和血、调经止痛、润燥滑肠之功效,用于治疗血虚、面色萎黄、眩晕心悸、血虚、或兼有瘀滞的月经不调、经闭、痛经、虚寒性腹痛、冠心病心绞痛、风湿痹痛、跌打损伤;
鹿鞭,性味:味甘、咸、性温,具有补肾精、壮肾阳、益精、强腰膝之功效,用于治疗肾虚劳损、腰膝酸痛、耳聋耳鸣、阳痿、遗精、早泄、宫冷不孕、带下清稀;
鱼鳔,性味:味甘、性平,具有补肝肾、养血止血、散瘀消肿之功效,用于治疗肾虚遗精、腰膝无力、腰痛、眩晕耳鸣、白带、习惯性流产、血虚筋挛、产后风痉、破伤风、癫痫、再生障碍性贫血、吐血、尿血、崩漏、外伤出血、阴疽、瘘管、慢性溃疡、皲裂、痛风、痔疮等症;
五味子,性味:味酸、性温,具有收敛固涩、益气生津、宁心安神之功效,用于治疗咳嗽虚喘、梦遗滑精、尿颇遗尿、久泻不止、自汗盗汗、津伤口渴、心悸失眠;
牛膝,性味:苦、酸、性平,具有补肝肾、强筋骨、活血通经、引敌国(火)下行、利尿通淋之功效,用于治疗腰膝酸痛、下肢痿软、血滞经闭、痛经、产后血瘀腹痛、徵瘕、胞衣不下、热淋、血淋、跌打损伤、痈肿恶疮、咽喉肿痛;
海龙,性味:味甘、咸、性温,具有补肾壮阳、散结消肿之功效,用于治疗阳痿、遗精、不育、肾虚作喘、癥瘕积聚、瘰疬瘿瘤、跌打损伤、痈肿疔疮;
海马,性味:味甘、咸、性温,具有补肾壮阳、散结消肿之功效,用于治疗肾虚阳痿、宫冷不孕遗尿、虚喘、症瘕积聚、跌打损伤、痈疮肿毒;
蛤蚧,性味:味咸、性平,具有益肾补肺、定喘止嗽之功效,用于治疗肺肾两虚气喘咳嗽、虚劳咳嗽、咯血、肾虚阳痿、遗精、小便频数、消渴等症;
阿胶,性味:甘、平,具有补血、止血、滋阴润燥之功效,用于治疗血虚萎黄、眩晕、心悸、多种出血证、阴虚证及燥证、温燥伤肺、干咳无痰等症;
龟甲胶,性味:咸、甘、凉,具有滋阴、养血、止血之功效,用于治疗阴虚潮热、骨蒸盗汗、腰膝酸软、血虚萎黄、崩漏带下;
冬虫夏草,性味:甘、温、香,具有保肺气、实腠理、补肾益精之功效,用于治疗肺虚咳喘、劳嗽痰血、自汗、盗汗、肾亏阳痿、遗精、腰膝酸痛;
车前子,性味:甘、微寒,具有清热利尿、渗湿通淋、明目、祛痰之功效,用于治疗水肿胀满、热淋涩痛、暑湿泄泻、目赤肿痛、痰热咳嗽。
本发明药物是基于中医治疗肾阳虚衰及气虚血亏的原则,从依据肾阳虚衰及气虚血亏的病理机制及药理作用认为:就肾阳虚衰及气虚血亏,本发明所提供的药物中的各原料中药药效共奏,对上述疾病有很好的治疗效果。
具体实施方式
本发明就是针对上述肾阳虚衰及气虚血亏的治疗而提出的一种中药配方,采用该配方制备的药物药效好,见效快,是一个标本兼治的中药组方,特别适合临床使用。下面结合本发明的具体实施方式作进一步详细的描述:
实施例1:
一种可有效治疗肾阳虚衰及气虚血亏的新型中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
人参95g、杜仲140g、枸杞子190g、肉桂80g、山药270g、淫羊藿80g、锁阳120g、茯苓230g、肉苁蓉120g、附子70g、牡丹皮95g、菟丝子120g、熟地黄280g、山茱萸95g、泽泻120g、仙茅80g、韭菜子80g、黄芪280g、当归120g、鹿鞭120g、鱼鳔280g、五味子50g、牛膝140g、海龙95g、海马95g、蛤蚧60g、阿胶120g、龟甲胶80g、冬虫夏草95g、车前子140g。
实施例2:
一种可有效治疗肾阳虚衰及气虚血亏的新型中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
人参105g、杜仲160g、枸杞子220g、肉桂90g、山药310g、淫羊藿90g、锁阳140g、茯苓260g、肉苁蓉140g、附子80g、牡丹皮105g、菟丝子140g、熟地黄320g、山茱萸105g、泽泻140g、仙茅90g、韭菜子90g、黄芪310g、当归140g、鹿鞭140g、鱼鳔310g、五味子60g、牛膝160g、海龙105g、海马105g、蛤蚧70g、阿胶140g、龟甲胶90g、冬虫夏草105g、车前子160g。
实施例3:
一种可有效治疗肾阳虚衰及气虚血亏的新型中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
人参120g、杜仲180g、枸杞子250g、肉桂100g、山药350g、淫羊藿100g、锁阳160g、茯苓300g、肉苁蓉160g、附子90g、牡丹皮120g、菟丝子160g、熟地黄380g、山茱萸120g、泽泻160g、仙茅100g、韭菜子100g、黄芪350g、当归160g、鹿鞭160g、鱼鳔350g、五味子70g、牛膝180g、海龙120g、海马120g、蛤蚧80g、阿胶160g、龟甲胶100g、冬虫夏草120g、车前子180g。
典型病例
经临床诊断治疗肾阳虚衰及气虚血亏病患者共2100例,年龄为38岁以上的1225例,只有875例为38岁以下。2100例患者痊愈的1925例,有效的175例,总有效率达100%。

Claims (3)

1.一种可有效治疗肾阳虚衰及气虚血亏的新型中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
人参30~120g、杜仲60~180g、枸杞子100~250g、肉桂30~100g、山药150~350g、淫羊藿30~100g、锁阳50~160g、茯苓150~300g、肉苁蓉100~160g、附子30~90g、牡丹皮60~120g、菟丝子60~160g、熟地黄100~380g、山茱萸50~120g、泽泻60~160g、仙茅30~100g、韭菜子30~100g、黄芪150~350g、当归80~160g、鹿鞭60~160g、鱼鳔100~350g、五味子30~70g、牛膝50~180g、海龙30~120g、海马30~120g、蛤蚧30~80g、阿胶50~160g、龟甲胶30~100g、冬虫夏草50~120g、车前子100~180g。
2.根据权利要求1所述的可有效治疗肾阳虚衰及气虚血亏的新型中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
人参38~105g、杜仲70~160g、枸杞子115~220g、肉桂38~90g、山药170~310g、淫羊藿38~90g、锁阳60~140g、茯苓170~260g、肉苁蓉115~140g、附子38~80g、牡丹皮70~105g、菟丝子70~140g、熟地黄115~320g、山茱萸60~105g、泽泻70~140g、仙茅38~90g、韭菜子38~90g、黄芪180~310g、当归90~140g、鹿鞭70~140g、鱼鳔115~310g、五味子38~60g、牛膝60~160g、海龙38~105g、海马38~105g、蛤蚧38~70g、阿胶60~140g、龟甲胶38~90g、冬虫夏草58~105g、车前子115~160g。
3.根据权利要求1至2所述的可有效治疗肾阳虚衰及气虚血亏的新型中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
人参95g、杜仲140g、枸杞子190g、肉桂80g、山药270g、淫羊藿80g、锁阳120g、茯苓230g、肉苁蓉120g、附子70g、牡丹皮95g、菟丝子120g、熟地黄280g、山茱萸95g、泽泻120g、仙茅80g、韭菜子80g、黄芪280g、当归120g、鹿鞭120g、鱼鳔280g、五味子50g、牛膝140g、海龙95g、海马95g、蛤蚧60g、阿胶120g、龟甲胶80g、冬虫夏草95g、车前子140g。
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CN108014289A (zh) * 2017-12-26 2018-05-11 慈中华 用于调理阳虚体质的中药膏方及其加工方法
CN108102865A (zh) * 2018-03-09 2018-06-01 童国柱 一种壮阳醉虾酒
CN108310201A (zh) * 2018-04-09 2018-07-24 北京科泰健业企业管理有限公司 一种固本养元中药及其喷剂、药膏的制备方法
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CN110638967A (zh) * 2019-09-20 2020-01-03 四川省众生缘农业科技开发有限公司 一种益气、补肾、健脾、活血、通络的中药
CN112755113A (zh) * 2021-03-18 2021-05-07 盛常斌 具有育阴潜阳的药物及其制备方法
CN112755113B (zh) * 2021-03-18 2022-04-22 盛常斌 具有育阴潜阳的药物及其制备方法
CN113230352A (zh) * 2021-06-28 2021-08-10 李亚娜 一种滋阴养肾保健中药及其制备方法

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