CN106729054A - A kind of Chinese herbal feed additive for preventing and treating sheep endoparasite and preparation method thereof - Google Patents
A kind of Chinese herbal feed additive for preventing and treating sheep endoparasite and preparation method thereof Download PDFInfo
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- CN106729054A CN106729054A CN201611188780.2A CN201611188780A CN106729054A CN 106729054 A CN106729054 A CN 106729054A CN 201611188780 A CN201611188780 A CN 201611188780A CN 106729054 A CN106729054 A CN 106729054A
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Abstract
The present invention provides a kind of Chinese herbal feed additive for preventing and treating sheep endoparasite and preparation method thereof, is related to field of feed, and the Chinese herbal feed additive is mainly made up of following raw material：Betelnut extract, the fruit of Rangoon creeper, pumpkin seeds, thinleaf loosestrife, G1ycosmis Pentaphylla (Retz) Correa. (G1ycosmis arborea (Roxb.)DC.), aloe, Chinese torreyanut, folium sennae, saline cistanche, gemma agrimoninae, rhizome of cyrtomium, rhizoma imperatae, dried lacquer, asafoetide, black ugly and Radix Glycyrrhizae.The processing method that the present invention also provides said herbal medicine feed addictive, comprises the following steps：(1) weigh；(2) medicine puree is prepared；(3) mixed-powder is prepared；(4) admixing medical solutions A is prepared；(5) admixing medical solutions B is prepared；(6) Chinese herbal feed additive is prepared.Feed addictive tool desinsection, effect of expelling parasite that the present invention is provided, while focusing on reducing fever and causing diuresis, function of spleen and stomach regulating, its drug effect is gentle, reach it is ill cure the disease, the effect of disease-free diseases prevention, in addition, the constitution of sheep can be improved using the present invention, survival rate is improved, market efficiency is increased.
Description
【Technical field】
The present invention relates to field of feed, and in particular to a kind of to add for preventing and treating the Chinese herbal feed of sheep endoparasite
Plus agent and preparation method thereof.
【Background technology】
In modern sheep raising industry, sheep parasite disease is to cause the price of deed and a bad weight of plant's economic benefit
Factor is wanted, without the enough attention that can cause producer, sheep parasite is divided into be posted in vivo for many times harm of parasite
The infested and major class of vermin two, endoparasite mainly has roundworm, pinworm, tapeworm, whipworm, oesophagostome etc., and this is several
Harm of the parasite to sheep body is big, and adult fights for nutritional ingredient with sheep, and migratory larvae destroys the intestinal wall of sheep, liver and lungs group
Structure and physiological function are knitted, causes the daily gain of sheep to reduce, the problems such as premunition decline；Vermin mainly have mite,
Louse, flea, mosquitos and flies etc., these parasites not only disturb the normal life of sheep, reduce the price of deed, influence the growth speed of sheep
Degree, serious loss is caused to sheep husbandry.
At present, the medicine of western medical treatment parasitic disease mainly has：Ivermectin, AVM, albendazole, toluene miaow
Azoles, levamisol, citric acid send a series of insecticide such as piperazine, but have certain limitation, and current anthelmintic can only
It is effective for one or two kinds of parasite, and have certain side effect, it is unfavorable for the growth of sheep.
The traditional Chinese medical science thinks that parasitic disease is primarily referred to as the food that is polluted by parasitic ovum of feed, or Human Water Contact, epidemic disease soil etc.
And the disease for causing.The drawbacks of Chinese traditional treatment sheep parasite disease can not only overcome western medical treatment, and diagnosis and treatment, plan as a whole simultaneous
Turn round and look at, focus of going directly, therapeutic effect significantly, and has no toxic side effect, not the only effect of expelling parasite, moreover it is possible to strengthen the immunity of sheep, promote
Enter the growth of sheep, effectively improve the survival rate of sick sheep, increase economic efficiency.
【The content of the invention】
In view of this, add for preventing and treating the Chinese herbal feed of sheep endoparasite object of the present invention is to provide a kind of
Plus agent and preparation method thereof, feed addictive tool desinsection, effect of expelling parasite that the present invention is provided, while focusing on reducing fever and causing diuresis, adjusting
Reason taste, and its drug effect is gentle, reach it is ill cure the disease, the effect of disease-free diseases prevention does not have any side-effects, and cures mainly sheep parasite
Disease, good effect, instant effect, the effect of desinsection can not only be played, and can also lead to intestines lead it is stagnant, polypide is excluded it is external, in addition, making
The constitution of sheep can be improved with feed addictive of the invention, strengthen the immunity of its own, improve survival rate, increase market effect
Benefit.
In order to solve the above-mentioned technical problem, present invention employs following technical scheme：
A kind of Chinese herbal feed additive for preventing and treating sheep endoparasite, the Chinese herbal feed additive is by following heavy
The raw material for measuring part is made：Betelnut extract 20-35 parts, fruit of Rangoon creeper 10-15 parts, pumpkin seeds 20-35 parts, thinleaf loosestrife 20-
35 parts, G1ycosmis Pentaphylla (Retz) Correa. (G1ycosmis arborea (Roxb.)DC.) 20-35 parts, aloe 10-25 parts, Chinese torreyanut 10-25 parts, folium sennae 10-25 parts, saline cistanche 10-25 parts, crane
Careless bud 8-12 parts, rhizome of cyrtomium 8-12 parts, rhizoma imperatae 8-12 parts, dried lacquer 8-12 parts, asafoetide 8-12 parts, black ugly 8-12 parts and Radix Glycyrrhizae 5-10
Part.
Further, the Chinese herbal feed additive is made up of the raw material of following weight portion：28 parts of betelnut extract, make monarch
12 parts of son, 28 parts of pumpkin seeds, 28 parts of thinleaf loosestrife, 28 parts of G1ycosmis Pentaphylla (Retz) Correa. (G1ycosmis arborea (Roxb.)DC.), 18 parts of aloe, 18 parts of Chinese torreyanut, folium sennae 18
Part, 18 parts of saline cistanche, 10 parts of gemma agrimoninae, 10 parts of rhizome of cyrtomium, 10 parts of rhizoma imperatae, 10 parts of dried lacquer, 10 parts of asafoetide, black ugly 10 parts and Radix Glycyrrhizae
7 parts.
Further, the raw material composition also includes 6-18 parts of the cellulase aqueous solution；The cellulase aqueous solution
It is by the cellulase and pure water in mass ratio 1 of 20,000-15 ten thousand u/g：50-80 is prepared and obtained.
Further, the aqueous areca nut extract is obtained by the following method：In the environment of being 45-50 DEG C in temperature by betel nut
Dry or dry, then carry out removal of impurities, crush, soak 2-3 in the ethanol water of 70-85wt% at room temperature afterwards
My god, then to be filtered, collection filtrate is standby, and filter residue is repeated into immersion 2-3 times, merging filtrate, at 40 DEG C in the same way
Under be concentrated under reduced pressure into density for 1.20-1.30g/ml, obtain extract medicinal extract；Extract medicinal extract is done with spray dryer
It is dry, obtain betelnut extract.
Further, the EAT of the spray dryer is 170-180 DEG C, and leaving air temp is 70-85 DEG C, charging speed
It is 7-11ml/min to spend, and feeding temperature is 40-50 DEG C.
The present invention also provides the preparation method of said herbal medicine feed addictive, specifically includes following steps：
(1) weigh：Each bulk drug is weighed by weight；
(2) medicine puree is prepared：Length is each cut into after aloe, the fruit of Rangoon creeper, G1ycosmis Pentaphylla (Retz) Correa. (G1ycosmis arborea (Roxb.)DC.) and thinleaf loosestrife are cleaned
Fragment less than 2cm, is then mixed with pumpkin seeds and is put into Steam by water bath 40-60min in pot, is subsequently poured into mixer and crushes
Stir into medicine puree standby；
(3) mixed-powder is prepared：Broken section of length less than 2cm is cut into after Chinese torreyanut, folium sennae and saline cistanche are cleaned, then
It is put into together in drying baker and dries, taking-up is placed on the place of drying and naturally cools to and pour into mechanical crushing in powder beater again after room temperature and be
The mixed-powder of 30 mesh standard sieves is standby；
(4) admixing medical solutions A is prepared：The mixed-powder of the medicine puree of step (2), step (3) is mixed, cellulase water is added
Solution soaks 3-4h to dipped medicinal material surface 1-2cm after stirring evenly, and obtains mixed soaking solution, is boiled to water is added in mixed soaking solution
30-40min is endured slowly with slow fire after boiling, its filtrate is filtered and take, and obtains the weight of admixing medical solutions A, the mixed soaking solution and water
Than being 3:1；
(5) admixing medical solutions B is prepared：Gemma agrimoninae, rhizome of cyrtomium, rhizoma imperatae, dried lacquer, asafoetide and black ugly mixing are put into gauze bag,
Then following treatment is carried out：A. once extract：Mixing medicinal material is put into Chinese medicine extracting tank, toward the interior injection mixing medicine of extractor
The water of 10-15 times of material weight, extracts 2-3 hours, and Extracting temperature is 70-80 DEG C, after having extracted, the mixture in tank is consolidated
Liquid is separated, and discharges an extract solution；B. second extraction：The solid mixt material obtained after once extracting is put into extractor,
Again toward the water of 2-5 times of injection solid mixt material weight in extractor, extract 1-2 hours, Extracting temperature is 70-80 DEG C, is extracted
After complete, by the mixed material separation of solid and liquid in tank, secondary raffinate is obtained；C. an extract solution and secondary raffinate are merged,
Filtering obtains admixing medical solutions B after going the removal of impurity；
(6) Chinese herbal feed additive is prepared：By step (4) gained admixing medical solutions A, step (5) gained admixing medical solutions B with
And aqueous areca nut extract is mixed, stirred, the relative density of solution is then concentrated into for 1.20-1.25, obtain Chinese herbal feed
Additive, the condition determination of relative density is room temperature, obtains Chinese herbal feed additive.
Further, the drying temperature of drying baker is 100-120 DEG C in the step (3), and drying time is 8-10h.
Part material correlation properties of the present invention are now done into following brief introduction：
Betel nut：Bitter, pungent, warm in nature, returns spleen, stomach, large intestine channel.With expelling parasite, disperse accumulations, lower gas, water-filling, detumescence, preventing malaria
Effect, cure mainly malnutrition due to parasitic infestation infantile malnutrition due to digestive disturbances or intestinalparasites disease, food stagnation do not disappear, abdominal distention, weight after rush down dysentery, constipation, hernia, tinea pedis, oedema, malaria.Its
Contained arecaline has paralysis taenia ovis, teniarhynchosis, dwarf tapeworm to act on, and polypide is produced flaccid paralysis, and taenia ovis is acted on
It is more powerful, each portion of polypide can be made to paralyse.
The fruit of Rangoon creeper：Its is sweet, warm in nature, enters spleen, stomach, large intestine channel.With desinsection, disperse accumulations, roundworm stomachache, children are controlled in invigorating the spleen
The effect of infantile malnutrition due to digestive disturbances or intestinalparasites, breast food stagnation, abdominal distension, rush down dysentery, it is mainly used in roundworm, enterobiasis, abdominal pain due to enterositosis, infantile malnutrition.
Pumpkin seeds：Its is sweet, mild-natured.Returning stomach, large intestine channel has tonifying middle-Jiao and Qi, and anti-inflammatory analgetic, removing toxic substances desinsection, hypoglycemic quenches the thirst
Effect；Cure mainly the illness such as the prolonged illness deficiency of vital energy, weakness of the spleen and the stomach, shortness of breath and lassitude, loose stool, diabetes, roundworm.
Thinleaf loosestrife：Leaf from dicotyledon medicine Ofthe Primulaceae, its bitter is cold in nature, enters Liver Channel.Tool
There is expelling parasite disinsection efficiency, be a kind of medicine for curing mainly roundworm and heating.
G1ycosmis Pentaphylla (Retz) Correa. (G1ycosmis arborea (Roxb.)DC.)：Its taste is pungent, puckery, cold in nature, Return liver, small intestine two are passed through.G1ycosmis Pentaphylla (Retz) Correa. (G1ycosmis arborea (Roxb.)DC.) is dicotyledon medicine rue
The leaf of section's plant G1ycosmis Pentaphylla (Retz) Correa. (G1ycosmis arborea (Roxb.)DC.), rich in the small tangerine glucoside in mountain, salicoside, tan acid anhydride, carbohydrate and tannin, with clearing heat and detoxicating, desinsection
Effect, be mainly used in the damp-warm diseases initial stage heating, jaundice with damp-heat pathogen, eczema, ulcer sores, Enterozoa, roundworm disease, hookworm disease,
Enterobiasis.
Aloe：Its bitter and puckery flavor, it is cold in nature, return stomach, large intestine channel.With purging intense heat, stimulate the menstrual flow, desinsection the effect of removing toxic substances, can be used to control
Gonorrhoea, hematuria, women's Amenorrhea under band, pediatric epilepsy scared, infantile malnutrition due to digestive disturbances or intestinalparasites are scalded, hemorrhoid, scabies, carbuncle swells etc..Contain substantial amounts of ammonia in aloe
Base acid, vitamin, polysaccharide compound, various enzymes and mineral matter, with bactericidal antiphlogistic, strengthen immunologic function, remove endotoxin
With the effect of free radical, constipation, prevention colitis can be released, improve blood circulation, acne-removing, skin-nourishing promotes whole body health.Due to
Organic acid contained by aloe is the intermediate product of fat and protein metabolism, is to carry out carbohydrate, fat and protein three
The important step of person's metabolism contact.
Chinese torreyanut：It is sweet, it is mild-natured, return large intestine channel.There are killing insect and eliminating accumulation, moistening dryness for relaxing bowels to effect.Be mainly used in hookworm, roundworm,
Taeniasis, abdominal pain due to enterositosis, infantile malnutrition, constipation.
Folium sennae：Sweet, hardship, it is cold in nature, return large intestine channel.There are stagnant disperse accumulations, defaecation Li Shui, antibacterial and detoxicating.Cure mainly：Heat
Knot is stagnant, fullness and oppression of chest and abdomen, suffers from constipation, the disease such as gastrorrhagia, can promote intestines peristalsis, cleaning intestine, protection liver.
Saline cistanche：It is sweet, salty, it is warm in nature, return kidney, large intestine channel.Energy kidney-replenishing, benefiting essence-blood relaxes bowel.For intestinal dryness just
The secret, insufficiency of the kidney yang, essence and blood void are lost, impotence or infertile, soreness and weakness of waist and knees, and muscles and bones is powerless to wait disease, moreover it is possible to effectively improve immunity.
Gemma agrimoninae：It is bitter, puckery, it is cool in nature.Return liver, small intestine, large intestine channel.Bitter cool drop-down, is apt to kill tapeworm, simultaneous to rush down lower and be beneficial to worm
Body is discharged, to control the key medicine of taeniasis.
Rhizome of cyrtomium：Bitter, is slightly cold, Return liver, the spleen channel.Effect：It is clearing heat and detoxicating, hemostasis, desinsection.Be usually used in anemopyretic cold,
Warm macula hematemesis, uterine bleeding is had blood in stool and various intestinal parasitical diseases.
Rhizoma imperatae：It is sweet, it is cold in nature.Return lung, stomach, bladder warp.The effect of having cooling blood and hemostasis, reducing fever and causing diuresis.For treating heat
Sick polydipsia, spits blood, and bleeding from five sense organs or subcutaneous tissue, lung heat breathes heavily urgency, stomach energy hiccup, gonorrhoea, difficult urination, oedema, jaundice etc..
Dried lacquer：Taste is pungent, hardship, warm in nature, enter liver, spleen two are passed through.Energy desinsection dissipates, and by stomach, all are tangible stagnant, and stomach was both
Clearly, then the five internal organs are pacified certainly, the slow numbness knot self-regulated of impotence.
Asafoetide：Taste is pungent, mild-natured, returns spleen warp, stomach.Category qi-regulating drug, with disperse accumulations, changes lump in the abdomen, the effect of dissipate ruffian, desinsection.
It is black ugly：Bitter, cold in nature, return lung warp, kidney channel, large intestine channel.With under rushing down, diuresis, detumescence, expelling parasite the effects such as, cure mainly
The diseases such as edema of limbs and trunks, nephritic dropsy, cirrhotic ascites.
Radix Glycyrrhizae：Its is sweet, mild-natured, return 12 warps.There are removing toxic substances, eliminating the phlegm, analgesic, spasmolysis so that the pharmacological action such as anticancer.
In the traditional Chinese medical science, Radix Glycyrrhizae is invigorated the spleen and benefited qi, and moistening lung, emergency removing toxic substances, hundred medicines of mediation are coughed in taste.It is raw with curing mainly abscess of throat, pain subcutaneous ulcer sore, stomach and intestine
Road ulcer and antidote poison, food poisoning etc.；Honey is processed and cures mainly spleen and stomach function and go down, and big loose stool is thin, weak heating and cough, the heart
Throb with fear.
Chinese herbal feed additive of the invention with desinsection expelling parasite as principle, and led with clearing heat and detoxicating, logical intestines it is stagnant, in preventing and treating
While sheep parasite disease, moreover it is possible to improve its immunity, additive of the invention takes into full account the Chinese medicine of eighteen incompatibilities and nineteen counteraction
Learn from other's strong points to offset one's weaknesses between combination principle, each component, mutually collaboration, wherein：
Betel nut, the fruit of Rangoon creeper, pumpkin seeds, gemma agrimoninae, thinleaf loosestrife and G1ycosmis Pentaphylla (Retz) Correa. (G1ycosmis arborea (Roxb.)DC.) multi-flavor match, can desinsection disappear
Various parasites are had good disinsection efficiency by product；Aloe, Chinese torreyanut, folium sennae and several tastes of saline cistanche match, cleaning intestine,
Moistening dryness for relaxing bowels, polypide can be excreted and liver is played a protective role；Gemma agrimoninae, rhizome of cyrtomium, rhizoma imperatae, dried lacquer, asafoetide and
It is black it is ugly with purging intense heat and detonicating, inducing diuresis to remove edema, dispersing stagnated hepatoqi the effect of, Radix Glycyrrhizae can be invigorated the spleen and benefited qi, and moistening lung is coughed in taste, emergency removing toxic substances, be adjusted
With hundred medicines.All medicines share in side, Quan Fangcong integrally sets out, and diagnosis and treatment, compatibility is rigorous.
In sum, by adopting the above-described technical solution, the beneficial effects of the invention are as follows：
1. Chinese herbal feed additive manufacturing process rigorous and scientific of the invention, is carried out after material mixing with cellulase
Immersion, because the present invention is made up of the cell membrane of Chinese herbal medicine a large amount of celluloses, and cellulose directly cannot be disappeared by sheep
Change, it can be the glucose that can be digested and assimilated by sheep by cellulose decomposition to be soaked with cellulase, reduce crude fibre to sheep stomach and intestine
Injury.
2. the Chinese medicine composition is according to assistant and guide formula principle, is strengthened the body resistance to consolidate the constitution with monarch drug in a prescription, killing insect and eliminating accumulation；Ministerial drug with
Relax bowel, discharge polypide；Assistant is allowed to medicine with clearing heat and detoxicating, dispersing swelling and dissipating binds, inducing diuresis for treating strangurtia, function of spleen and stomach regulating；Wherein, betel nut paralysis
Polypide, the fruit of Rangoon creeper, thinleaf loosestrife killing insect and eliminating accumulation, pumpkin seeds removing toxic substances desinsection, tonifying middle-Jiao and Qi, G1ycosmis Pentaphylla (Retz) Correa. (G1ycosmis arborea (Roxb.)DC.) is clearing heat and detoxicating,
Drive away polypide, be monarch with five, killing insect and eliminating accumulation is strengthened the body resistance to consolidate the constitution；Ministerial drug in side：Aloe, Chinese torreyanut, folium sennae and saline cistanche, play altogether
Bactericidal antiphlogistic, relax bowel, cleaning intestine the effect of；Adjutant in side：Gemma agrimoninae, rhizome of cyrtomium, rhizoma imperatae, dried lacquer, asafoetide and black ugly,
The clearing heat and detoxicating, inducing diuresis to remove edema of row, the duty of function of spleen and stomach regulating；Make medicine：It is equipped with Radix Glycyrrhizae, clearing heat and cooling blood, coordinating the drug actions of a prescription, to strengthen each medicine work(
Effect；Ingeniously matched somebody with somebody with all medicine phases of monarch, negative and positive are mutually taken, mutual assistance in table, so as to reach killing insect and eliminating accumulation, clearing heat and detoxicating, tonifying middle-Jiao and Qi,
The effect of building up resistance, to sheep endoparasite therapeutic effect significantly, and gentle safety, has no toxic side effect, with Radix Glycyrrhizae to make
Medicine, is invigorated the spleen and benefited qi, and moistening lung, emergency removing toxic substances, hundred medicines of mediation are coughed in taste.
3. the Chinese herbal feed additive of present invention treatment sheep endoparasite is formed by 16 taste Chinese herbal medicine reasonable preparations,
Added in feed the additive assign feed desinsection effect, and its can not only kill adult in sheep body can lead to again intestines lead it is stagnant,
The polypide of kill is excreted, while focus on reducing fever and causing diuresis, function of spleen and stomach regulating, and its drug effect is gentle, no drug residue, when drug effect continues
Between it is long, be difficult after drug withdrawal recurrence, reach it is ill cure the disease, the effect of disease-free diseases prevention does not have any side-effects, and cures mainly sheep parasite
Disease, good effect, instant effect the effect of can not only play desinsection, can improve the constitution of sheep in addition, strengthen the immunity of its own,
Survival rate is improved, market efficiency is increased.
【Specific embodiment】
The following examples can help those skilled in the art that the present invention is more fully understood, but cannot be with any
Mode limits the present invention.
First, formulation Example
Embodiment 1
The feed addictive that the present embodiment is produced is made up of the raw material of following weight portion：20 parts of betelnut extract, make monarch
10 parts of son, 20 parts of pumpkin seeds, 20 parts of thinleaf loosestrife, 20 parts of G1ycosmis Pentaphylla (Retz) Correa. (G1ycosmis arborea (Roxb.)DC.), 10 parts of aloe, 10 parts of Chinese torreyanut, folium sennae 10
Part, 10 parts of saline cistanche, 8 parts of gemma agrimoninae, 8 parts of rhizome of cyrtomium, 8 parts of rhizoma imperatae, 8 parts of dried lacquer, 8 parts of asafoetide, black ugly 8 parts, 5 parts of Radix Glycyrrhizae and fibre
Plain 6 parts of the enzyme aqueous solution of dimension；
In above-mentioned formula, aqueous areca nut extract is obtained by the following method：Dried in the environment of being 45 DEG C in temperature by betel nut
Or dry, then carry out removal of impurities, crush, soaked 2 days in the ethanol water of 70wt% at room temperature afterwards, then by it
Filtering, collection filtrate is standby, and filter residue is repeated into immersion 2 times in the same way, and merging filtrate is concentrated under reduced pressure into close at 40 DEG C
It is 1.20g/ml to spend, and obtains extract medicinal extract；Extract medicinal extract is dried with spray dryer, the air intake of spray dryer
Temperature is 170 DEG C, and leaving air temp is 70 DEG C, and charging rate is 7ml/min, and feeding temperature is 40 DEG C, obtains betelnut extract；
The cellulase aqueous solution is by the cellulase and pure water in mass ratio 1 of 20,000 u/g：50 preparations are obtained.
Embodiment 2
The feed addictive that the present embodiment is produced is made up of the raw material of following weight portion：28 parts of betelnut extract, make monarch
12 parts of son, 28 parts of pumpkin seeds, 28 parts of thinleaf loosestrife, 28 parts of G1ycosmis Pentaphylla (Retz) Correa. (G1ycosmis arborea (Roxb.)DC.), 18 parts of aloe, 18 parts of Chinese torreyanut, folium sennae 18
Part, 18 parts of saline cistanche, 10 parts of gemma agrimoninae, 10 parts of rhizome of cyrtomium, 10 parts of rhizoma imperatae, 10 parts of dried lacquer, 10 parts of asafoetide, black ugly 10 parts, Radix Glycyrrhizae 7
10 parts of part and the cellulase aqueous solution；
In above-mentioned formula, aqueous areca nut extract is obtained by the following method：Dried in the environment of being 47 DEG C in temperature by betel nut
Or dry, then carry out removal of impurities, crush, soaked 2 days in the ethanol water of 78wt% at room temperature afterwards, then by it
Filtering, collection filtrate is standby, and filter residue is repeated into immersion 2 times in the same way, and merging filtrate is concentrated under reduced pressure into close at 40 DEG C
It is 1.25g/ml to spend, and obtains extract medicinal extract；Extract medicinal extract is dried with spray dryer, the air intake of spray dryer
Temperature is 175 DEG C, and leaving air temp is 77 DEG C, and charging rate is 10ml/min, and feeding temperature is 45 DEG C, obtains betelnut extract；
The cellulase aqueous solution is by the cellulase and pure water in mass ratio 1 of 80,000 u/g：70 preparations are obtained.
Embodiment 3
The feed addictive that the present embodiment is produced is made up of the raw material of following weight portion：35 parts of betelnut extract, make monarch
15 parts of son, 35 parts of pumpkin seeds, 35 parts of thinleaf loosestrife, 35 parts of G1ycosmis Pentaphylla (Retz) Correa. (G1ycosmis arborea (Roxb.)DC.), 25 parts of aloe, 25 parts of Chinese torreyanut, folium sennae 25
Part, 25 parts of saline cistanche, 12 parts of gemma agrimoninae, 12 parts of rhizome of cyrtomium, 12 parts of rhizoma imperatae, 12 parts of dried lacquer, 12 parts of asafoetide, black ugly 12 parts, Radix Glycyrrhizae
10 parts and 18 parts of the cellulase aqueous solution；
In above-mentioned formula, aqueous areca nut extract is obtained by the following method：Dried in the environment of being 50 DEG C in temperature by betel nut
Or dry, then carry out removal of impurities, crush, soaked 3 days in the ethanol water of 85wt% at room temperature afterwards, then by it
Filtering, collection filtrate is standby, and filter residue is repeated into immersion 3 times in the same way, and merging filtrate is concentrated under reduced pressure into close at 40 DEG C
It is 1.30g/ml to spend, and obtains extract medicinal extract；Extract medicinal extract is dried with spray dryer, the air intake of spray dryer
Temperature is 180 DEG C, and leaving air temp is 85 DEG C, and charging rate is 11ml/min, and feeding temperature is 50 DEG C, obtains betelnut extract；
The cellulase aqueous solution is by the cellulase and pure water in mass ratio 1 of 150,000 u/g：80 preparations are obtained.
2nd, Chinese herbal feed additive prepares embodiment
Embodiment 4
According to the formula of embodiment 1, a kind of preparation side for preventing and treating the Chinese herbal feed additive of sheep endoparasite
Method, comprises the following steps：
(1) weigh：Each bulk drug is weighed by weight；
(2) medicine puree is prepared：Length is each cut into after aloe, the fruit of Rangoon creeper, G1ycosmis Pentaphylla (Retz) Correa. (G1ycosmis arborea (Roxb.)DC.) and thinleaf loosestrife are cleaned
Fragment less than 2cm, is then mixed with pumpkin seeds and is put into Steam by water bath 40min in pot, is subsequently poured into crush in mixer and stirs
Mix medicine puree standby；
(3) mixed-powder is prepared：Broken section of length less than 2cm is cut into after Chinese torreyanut, folium sennae and saline cistanche are cleaned, then
Drying in drying baker is put into together, and the drying temperature of drying baker is 100 DEG C, and drying time is 8h, and taking-up is placed on nature at dry
It is cooled to after room temperature that to pour into the mixed-powder that mechanical crushing in powder beater was 30 mesh standard sieves again standby；
(4) admixing medical solutions A is prepared：The mixed-powder of the medicine puree of step (2), step (3) is mixed, cellulase water is added
Solution soaks 3h to dipped medicinal material surface 1cm after stirring evenly, and obtains mixed soaking solution, after adding water to boil in mixed soaking solution
30min is endured slowly with slow fire, its filtrate is filtered and take, admixing medical solutions A is obtained, and the mixed soaking solution is 3 with the weight ratio of water:1；
(5) admixing medical solutions B is prepared：Gemma agrimoninae, rhizome of cyrtomium, rhizoma imperatae, dried lacquer, asafoetide and black ugly mixing are put into gauze bag,
Then following treatment is carried out：A. once extract：Mixing medicinal material is put into Chinese medicine extracting tank, toward the interior injection mixing medicine of extractor
The water that 10 times of material weight, extracts 2 hours, and Extracting temperature is 70 DEG C, after having extracted, the mixture in tank is carried out into separation of solid and liquid,
Extract solution of discharge；B. second extraction：The solid mixt material obtained after once extracting is put into extractor, then past extraction
The water of 2 times of solid mixt material weight is injected in tank, is extracted 1 hour, Extracting temperature is 70 DEG C, after having extracted, will be mixed in tank
Compound material separation of solid and liquid, obtains secondary raffinate；C. an extract solution and secondary raffinate are merged, filtering is obtained after going the removal of impurity
To admixing medical solutions B；
(6) Chinese herbal feed additive is prepared：By step (4) gained admixing medical solutions A, step (5) gained admixing medical solutions B with
And aqueous areca nut extract is mixed, stirred, the relative density of solution is then concentrated into for 1.20 obtain Chinese herbal feed additive,
The condition determination of relative density is room temperature, obtains Chinese herbal feed additive.
Embodiment 5
According to the formula of embodiment 2, a kind of preparation side for preventing and treating the Chinese herbal feed additive of sheep endoparasite
Method, comprises the following steps：
(1) weigh：Each bulk drug is weighed by weight；
(2) medicine puree is prepared：Length is each cut into after aloe, the fruit of Rangoon creeper, G1ycosmis Pentaphylla (Retz) Correa. (G1ycosmis arborea (Roxb.)DC.) and thinleaf loosestrife are cleaned
Fragment less than 2cm, is then mixed with pumpkin seeds and is put into Steam by water bath 50min in pot, is subsequently poured into crush in mixer and stirs
Mix medicine puree standby；
(3) mixed-powder is prepared：Broken section of length less than 2cm is cut into after Chinese torreyanut, folium sennae and saline cistanche are cleaned, then
Drying in drying baker is put into together, and the drying temperature of drying baker is 110 DEG C, and drying time is 9h, and taking-up is placed on nature at dry
It is cooled to after room temperature that to pour into the mixed-powder that mechanical crushing in powder beater was 30 mesh standard sieves again standby；
(4) admixing medical solutions A is prepared：The mixed-powder of the medicine puree of step (2), step (3) is mixed, cellulase water is added
Solution soaks 3h to dipped medicinal material surface 1.5cm after stirring evenly, and obtains mixed soaking solution, is boiled to water is added in mixed soaking solution
35min is endured slowly with slow fire afterwards, its filtrate is filtered and take, admixing medical solutions A is obtained, and the mixed soaking solution is 3 with the weight ratio of water:
1；
(5) admixing medical solutions B is prepared：Gemma agrimoninae, rhizome of cyrtomium, rhizoma imperatae, dried lacquer, asafoetide and black ugly mixing are put into gauze bag,
Then following treatment is carried out：A. once extract：Mixing medicinal material is put into Chinese medicine extracting tank, toward the interior injection mixing medicine of extractor
The water that 12 times of material weight, extracts 2.5 hours, and Extracting temperature is 75 DEG C, after having extracted, the mixture in tank is carried out into solid-liquid point
From extract solution of discharge；B. second extraction：The solid mixt material obtained after once extracting is put into extractor, then past
The water of 3 times of solid mixt material weight is injected in extractor, is extracted 1.5 hours, Extracting temperature is 75 DEG C, after having extracted, by tank
Interior mixed material separation of solid and liquid, obtains secondary raffinate；C. an extract solution and secondary raffinate are merged, removal of impurities is gone in filtering
Admixing medical solutions B is obtained after matter；
(6) Chinese herbal feed additive is prepared：By step (4) gained admixing medical solutions A, step (5) gained admixing medical solutions B with
And aqueous areca nut extract is mixed, stirred, it is 1.22 to be then concentrated into the relative density of solution, obtains Chinese herbal feed addition
Agent, the condition determination of relative density is room temperature, obtains Chinese herbal feed additive.
Embodiment 6
According to the formula of embodiment 3, a kind of preparation side for preventing and treating the Chinese herbal feed additive of sheep endoparasite
Method, comprises the following steps：
(1) weigh：Each bulk drug is weighed by weight；
(2) medicine puree is prepared：Length is each cut into after aloe, the fruit of Rangoon creeper, G1ycosmis Pentaphylla (Retz) Correa. (G1ycosmis arborea (Roxb.)DC.) and thinleaf loosestrife are cleaned
Fragment less than 2cm, is then mixed with pumpkin seeds and is put into Steam by water bath 60min in pot, is subsequently poured into crush in mixer and stirs
Mix medicine puree standby；
(3) mixed-powder is prepared：Broken section of length less than 2cm is cut into after Chinese torreyanut, folium sennae and saline cistanche are cleaned, then
Drying in drying baker is put into together, and the drying temperature of drying baker is 120 DEG C, and drying time is 10h, and taking-up is placed on nature at dry
It is cooled to after room temperature that to pour into the mixed-powder that mechanical crushing in powder beater was 30 mesh standard sieves again standby；
(4) admixing medical solutions A is prepared：The mixed-powder of the medicine puree of step (2), step (3) is mixed, cellulase water is added
Solution soaks 4h to dipped medicinal material surface 2cm after stirring evenly, and obtains mixed soaking solution, after adding water to boil in mixed soaking solution
40min is endured slowly with slow fire, its filtrate is filtered and take, admixing medical solutions A is obtained, and the mixed soaking solution is 3 with the weight ratio of water:1；
(5) admixing medical solutions B is prepared：Gemma agrimoninae, rhizome of cyrtomium, rhizoma imperatae, dried lacquer, asafoetide and black ugly mixing are put into gauze bag,
Then following treatment is carried out：A. once extract：Mixing medicinal material is put into Chinese medicine extracting tank, toward the interior injection mixing medicine of extractor
The water that 15 times of material weight, extracts 3 hours, and Extracting temperature is 80 DEG C, after having extracted, the mixture in tank is carried out into separation of solid and liquid,
Extract solution of discharge；B. second extraction：The solid mixt material obtained after once extracting is put into extractor, then past extraction
The water of 5 times of solid mixt material weight is injected in tank, is extracted 2 hours, Extracting temperature is 80 DEG C, after having extracted, will be mixed in tank
Compound material separation of solid and liquid, obtains secondary raffinate；C. an extract solution and secondary raffinate are merged, filtering is obtained after going the removal of impurity
To admixing medical solutions B；
(6) Chinese herbal feed additive is prepared：By step (4) gained admixing medical solutions A, step (5) gained admixing medical solutions B with
And aqueous areca nut extract is mixed, stirred, it is 1.25 to be then concentrated into the relative density of solution, obtains Chinese herbal feed addition
Agent, the condition determination of relative density is room temperature, obtains Chinese herbal feed additive.
3rd, sheep feed prepares embodiment
Embodiment 7
The gained Chinese herbal feed additive of embodiment 4 is mixed with basic sheep feed, makes ratio of the additive in sheep feed
Example is 2wt%, obtains sheep feed.
Embodiment 8
The gained Chinese herbal feed additive of embodiment 5 is mixed with basic sheep feed, makes ratio of the additive in sheep feed
Example is 3wt%, obtains sheep feed.
Embodiment 9
The gained Chinese herbal feed additive of embodiment 6 is mixed with basic sheep feed, makes ratio of the additive in sheep feed
Example is 4wt%, obtains sheep feed.
Comparative example 1
It is supplied to sheep to eat basic sheep feed, basic sheep feed such as following table：
The basic sheep feed of table 1
| Type | Mass fraction |
| Corn | 59 |
| Dregs of beans | 27.5 |
| Bone meal | 5 |
| Rice bran | 6.5 |
| Calcium monohydrogen phosphate | 1 |
| Premix | 1 |
| Amount to | 100 |
Comparative example 2
Commercially available parasite medicine is coordinated to be supplied to sheep to eat basic sheep feed；
Selection commercially available parasite medicine be：The Guangxi Yi Muyuan biology ball peaceful oral liquids of good fortune.
Experimental example
In order to further illustrate the application value of method for breeding of the present invention, implement people the sheep son of 500 just births is average
Be divided into 5 groups, experimental period be from sheep date of birth to day is delivered for sale, be contrast experiment：
Contrast experiment 1：
The symptom that sheep occurs is situations below, observes and records under above-mentioned five groups of method for breeding and conditions occurs, such as the institute of table 2
Show, symptom is summarized as follows：
Symptom explanation：Suffer from lean and haggard sheep, hobby of eating unusual thing, stomachache, lose the appetite, performance is had the fidgets, activity is poor；Through
, there is number containing worm's ovum (EPG, unit in every gram that suffers from sheep excrement of these symptoms in diagnosis：Individual/g) 403, including：Roundworm,
The parasites such as whipworm, oesophagostome, kidney nematode, balantidium Coli.
Table 2
As known from Table 2：The sheep for being added with the formula of three groups of embodiments of the invention in five groups in feed does not go down with, into
Length is more healthy, and survival rate is high.
Contrast test 2：
The feeds that the raw sheep production process of 50 easy excessive internal heats, stool odor weight and poor appetite is fed are tested, divides 5
Group carries out contrast test, every group 10：
Through Analysis-Test Research Center, Guangxi Zhuang Autonomous Region's sampling inspection, assay is as follows：
After one week of feed of edible embodiment 7-8, interior thermal phenomenon has disappeared the sheep of present invention group, one month
Afterwards, interior thermal phenomenon disappears substantially, and sheep feed is active, and sheep stool odor is light；And after the feed of edible comparative example 1, above-mentioned symptom
It is not eased or has aggravated, is detected through excrement, number containing worm's ovum (EPG, unit in every gram of excrement of sheep in the group：Individual/g)
95, including：The parasites such as roundworm, whipworm, oesophagostome, kidney nematode, balantidium Coli, every gram of excrement of sheep of the invention
Just (EPG, unit of number containing worm's ovum in：Individual/g) 1；After the feed of edible comparative example 2, thermal phenomenon has disappeared in sheep, after one month,
Interior thermal phenomenon disappears substantially, but sheep feed is inactive, and feed mouthfeel is not liked.
Test result indicate that, feed addictive tool desinsection, effect of expelling parasite that the present invention is provided, while focusing on heat-clearing profit
Urine, function of spleen and stomach regulating, and its drug effect is gentle, reach it is ill cure the disease, the effect of disease-free diseases prevention does not have any side-effects, and cures mainly sheep
Parasitic disease, good effect, instant effect, the effect of desinsection can not only be played, and can also lead to intestines lead it is stagnant, polypide is excluded it is external,
In addition, the constitution of sheep can be improved using feed addictive of the invention, promote the appetite of sheep, strengthen the immunity of its own, carry
High-survival rate, increases market efficiency.
Although above the present invention is described in detail with a general description of the specific embodiments,
On the basis of the present invention, it can be made some modifications or improvements, this will be apparent to those skilled in the art.Cause
This, these modifications or improvements, belong to the scope of protection of present invention without departing from theon the basis of the spirit of the present invention.
Claims (7)
1. a kind of Chinese herbal feed additive for preventing and treating sheep endoparasite, it is characterised in that the Chinese herbal feed is added
Agent is made up of the raw material of following weight portion：Betelnut extract 20-35 parts, fruit of Rangoon creeper 10-15 parts, pumpkin seeds 20-35 parts, sharp leaf
Anthelmintic 20-35 parts, G1ycosmis Pentaphylla (Retz) Correa. (G1ycosmis arborea (Roxb.)DC.) 20-35 parts, aloe 10-25 parts, Chinese torreyanut 10-25 parts, folium sennae 10-25 parts, saline cistanche
10-25 parts, gemma agrimoninae 8-12 parts, rhizome of cyrtomium 8-12 parts, rhizoma imperatae 8-12 parts, dried lacquer 8-12 parts, asafoetide 8-12 parts, it is black ugly 8-12 parts
With Radix Glycyrrhizae 5-10 parts.
2. a kind of Chinese herbal feed additive for preventing and treating sheep endoparasite according to claim 1, its feature exists
In the Chinese herbal feed additive is made up of the raw material of following weight portion：28 parts of betelnut extract, 12 parts of the fruit of Rangoon creeper, pumpkin seeds
28 parts, 28 parts of thinleaf loosestrife, 28 parts of G1ycosmis Pentaphylla (Retz) Correa. (G1ycosmis arborea (Roxb.)DC.), 18 parts of aloe, 18 parts of Chinese torreyanut, 18 parts of folium sennae, 18 parts of saline cistanche,
10 parts of gemma agrimoninae, 10 parts of rhizome of cyrtomium, 10 parts of rhizoma imperatae, 10 parts of dried lacquer, 10 parts of asafoetide, black ugly 10 parts and 7 parts of Radix Glycyrrhizae.
3. a kind of Chinese herbal feed additive for preventing and treating sheep endoparasite according to claim 1, its feature exists
In the raw material composition also includes 6-18 parts of the cellulase aqueous solution；The cellulase aqueous solution is by 20,000-15 ten thousand u/g
Cellulase and pure water in mass ratio 1：50-80 is prepared and obtained.
4. a kind of Chinese herbal feed additive for preventing and treating sheep endoparasite according to claim 1, its feature exists
In the aqueous areca nut extract is obtained by the following method：Dry or dry in the environment of being 45-50 DEG C in temperature by betel nut,
Then carry out removal of impurities, crush, soaked 2-3 days in the ethanol water of 70-85wt% at room temperature afterwards, then by its mistake
Filter, collection filtrate is standby, and filter residue is repeated into immersion 2-3 times in the same way, and merging filtrate is concentrated under reduced pressure into close at 40 DEG C
It is 1.20-1.30g/ml to spend, and obtains extract medicinal extract；Extract medicinal extract is dried with spray dryer, betel nut is obtained and is carried
Take thing.
5. a kind of Chinese herbal feed additive for preventing and treating sheep endoparasite according to claim 4, its feature exists
In the EAT of the spray dryer is 170-180 DEG C, and leaving air temp is 70-85 DEG C, and charging rate is 7-11ml/
Min, feeding temperature is 40-50 DEG C.
6. a kind of for preventing and treating the Chinese herbal feed additive of sheep endoparasite according to claim any one of 1-5
Preparation method, it is characterised in that the preparation method comprises the following steps：
(1) weigh：Each bulk drug is weighed by weight；
(2) medicine puree is prepared：Length is each cut into after aloe, the fruit of Rangoon creeper, G1ycosmis Pentaphylla (Retz) Correa. (G1ycosmis arborea (Roxb.)DC.) and thinleaf loosestrife are cleaned to be less than
The fragment of 2cm, is then mixed with pumpkin seeds and is put into Steam by water bath 40-60min in pot, is subsequently poured into broken stirring in mixer
It is standby into medicine puree；
(3) mixed-powder is prepared：Broken section of length less than 2cm is cut into after Chinese torreyanut, folium sennae and saline cistanche are cleaned, then together
It is put into drying baker and dries, taking-up is placed on the place of drying and to naturally cool to that pour into mechanical crushing in powder beater again after room temperature be 30 mesh
The mixed-powder of standard screen is standby；
(4) admixing medical solutions A is prepared：The mixed-powder of the medicine puree of step (2), step (3) is mixed, the cellulase aqueous solution is added
To dipped medicinal material surface 1-2cm, 3-4h is soaked after stirring evenly, obtain mixed soaking solution, after adding water to boil in mixed soaking solution
30-40min is endured slowly with slow fire, its filtrate is filtered and take, admixing medical solutions A is obtained, and the mixed soaking solution is with the weight ratio of water
3:1；
(5) admixing medical solutions B is prepared：Gemma agrimoninae, rhizome of cyrtomium, rhizoma imperatae, dried lacquer, asafoetide and black ugly mixing are put into gauze bag, then
Carry out following treatment：A. once extract：Mixing medicinal material is put into Chinese medicine extracting tank, toward the interior injection mixing medicinal material weight of extractor
The water of 10-15 times of amount, extracts 2-3 hours, and Extracting temperature is 70-80 DEG C, after having extracted, the mixture in tank is carried out into solid-liquid point
From extract solution of discharge；B. second extraction：The solid mixt material obtained after once extracting is put into extractor, then past
The water of 2-5 times of solid mixt material weight is injected in extractor, is extracted 1-2 hours, Extracting temperature is 70-80 DEG C, after having extracted,
By the mixed material separation of solid and liquid in tank, secondary raffinate is obtained；C. an extract solution and secondary raffinate are merged, crosses and filter off
Admixing medical solutions B is obtained after the removal of impurity；
(6) Chinese herbal feed additive is prepared：By step (4) gained admixing medical solutions A, step (5) gained admixing medical solutions B and Bin
Bulky extract solution is mixed, is stirred, and is then concentrated into the relative density of solution for 1.20-1.25, obtains Chinese herbal feed addition
Agent, the condition determination of relative density is room temperature, obtains Chinese herbal feed additive.
7. a kind of preparation side for preventing and treating the Chinese herbal feed additive of sheep endoparasite according to claim 6
Method, it is characterised in that the drying temperature of drying baker is 100-120 DEG C in the step (3), and drying time is 8-10h.
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Cited By (5)
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| CN108813173A (en) * | 2018-06-28 | 2018-11-16 | 大新县科学技术情报研究所 | Mutton sheep ecologic breeding feed and preparation method thereof |
| CN108813174A (en) * | 2018-06-28 | 2018-11-16 | 大新县科学技术情报研究所 | Promote to digest and assimilate disease-resistant type feed addictive and its application |
| CN109287667A (en) * | 2018-11-09 | 2019-02-01 | 常宁市代发生态农业有限公司 | A kind of farm's disinfectant and preparation method thereof |
| CN111631305A (en) * | 2020-06-11 | 2020-09-08 | 南京农业大学 | Feed additive for improving ewe production and lamb growth performance |
| CN112843165A (en) * | 2019-11-28 | 2021-05-28 | 重庆琅烽生物科技(集团)有限公司 | Traditional Chinese medicine biological feed additive for treating toxoplasma gondii in animal body |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108813173A (en) * | 2018-06-28 | 2018-11-16 | 大新县科学技术情报研究所 | Mutton sheep ecologic breeding feed and preparation method thereof |
| CN108813174A (en) * | 2018-06-28 | 2018-11-16 | 大新县科学技术情报研究所 | Promote to digest and assimilate disease-resistant type feed addictive and its application |
| CN109287667A (en) * | 2018-11-09 | 2019-02-01 | 常宁市代发生态农业有限公司 | A kind of farm's disinfectant and preparation method thereof |
| CN112843165A (en) * | 2019-11-28 | 2021-05-28 | 重庆琅烽生物科技(集团)有限公司 | Traditional Chinese medicine biological feed additive for treating toxoplasma gondii in animal body |
| CN111631305A (en) * | 2020-06-11 | 2020-09-08 | 南京农业大学 | Feed additive for improving ewe production and lamb growth performance |
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Application publication date: 20170531 |