CN1064268A - 制备含有喹啉盐的药物组合物的方法 - Google Patents

制备含有喹啉盐的药物组合物的方法 Download PDF

Info

Publication number
CN1064268A
CN1064268A CN92101029A CN92101029A CN1064268A CN 1064268 A CN1064268 A CN 1064268A CN 92101029 A CN92101029 A CN 92101029A CN 92101029 A CN92101029 A CN 92101029A CN 1064268 A CN1064268 A CN 1064268A
Authority
CN
China
Prior art keywords
salt
quinolinium
oxethyl
hydroxyl
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN92101029A
Other languages
English (en)
Chinese (zh)
Inventor
R·J·艾夫
C·A·利奇
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Smithkl Ine Beecham
SmithKline Beecham Corp
Original Assignee
Smithkl Ine Beecham
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB919101919A external-priority patent/GB9101919D0/en
Priority claimed from GB919101918A external-priority patent/GB9101918D0/en
Application filed by Smithkl Ine Beecham filed Critical Smithkl Ine Beecham
Publication of CN1064268A publication Critical patent/CN1064268A/zh
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38Nitrogen atoms
    • C07D215/42Nitrogen atoms attached in position 4
    • C07D215/44Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CN92101029A 1991-01-29 1992-01-28 制备含有喹啉盐的药物组合物的方法 Pending CN1064268A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB919101919A GB9101919D0 (en) 1991-01-29 1991-01-29 Compound
GB919101918A GB9101918D0 (en) 1991-01-29 1991-01-29 Compound
GB9101919.0 1991-01-29
GB9101918.2 1991-01-29

Publications (1)

Publication Number Publication Date
CN1064268A true CN1064268A (zh) 1992-09-09

Family

ID=26298350

Family Applications (1)

Application Number Title Priority Date Filing Date
CN92101029A Pending CN1064268A (zh) 1991-01-29 1992-01-28 制备含有喹啉盐的药物组合物的方法

Country Status (18)

Country Link
EP (1) EP0569396A1 (ja)
JP (1) JPH06504541A (ja)
CN (1) CN1064268A (ja)
AP (1) AP337A (ja)
AU (1) AU652028B2 (ja)
CA (1) CA2099117A1 (ja)
CZ (1) CZ153293A3 (ja)
FI (1) FI933376A (ja)
HU (1) HUT67609A (ja)
IE (1) IE920267A1 (ja)
IL (1) IL100791A0 (ja)
MA (1) MA22401A1 (ja)
MX (1) MX9200338A (ja)
NO (1) NO932722D0 (ja)
NZ (1) NZ241408A (ja)
PT (1) PT100056A (ja)
SK (1) SK70993A3 (ja)
WO (1) WO1992012969A1 (ja)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9126438D0 (en) * 1991-12-12 1992-02-12 Smithkline Beecham Intercredit New quinoline derivatives
IS4164A (is) * 1993-06-11 1994-12-12 Ab Astra Efnasambönd sem hindra flæði magasýru
US5556863A (en) * 1993-06-11 1996-09-17 Astra Aktiebolag Compound for gastric acid secretion inhibition
USRE43932E1 (en) 1997-07-18 2013-01-15 Novartis Ag Crystal modification of a N-phenyl-2-pyrimidineamine derivative, processes for its manufacture and its use
US6852739B1 (en) 1999-02-26 2005-02-08 Nitromed Inc. Methods using proton pump inhibitors and nitric oxide donors
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
AU2002342917A1 (en) * 2001-11-19 2003-06-10 Altana Pharma Ag Reversible proton pump inhibitors for the treatment of airway disorders
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
CA2493618A1 (en) 2002-08-01 2004-02-12 Nitromed, Inc. Nitrosated proton pump inhibitors, compositions and methods of use
AU2004285394B2 (en) 2003-11-03 2009-01-08 Astrazeneca Ab Imidazo (1,2-A) pyridine derivatives for the treatment of silent gastro-esophageal reflux

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8804444D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds

Also Published As

Publication number Publication date
HUT67609A (en) 1995-04-28
IE920267A1 (en) 1992-07-29
FI933376A0 (fi) 1993-07-28
SK70993A3 (en) 1994-01-12
AP9200352A0 (en) 1992-01-31
AU652028B2 (en) 1994-08-11
NZ241408A (en) 1994-05-26
AU1179992A (en) 1992-08-27
CA2099117A1 (en) 1992-07-30
NO932722L (no) 1993-07-28
HU9302201D0 (en) 1993-10-28
MA22401A1 (fr) 1992-10-01
FI933376A (fi) 1993-07-28
PT100056A (pt) 1993-03-31
AP337A (en) 1994-04-08
WO1992012969A1 (en) 1992-08-06
EP0569396A1 (en) 1993-11-18
CZ153293A3 (en) 1993-12-15
MX9200338A (es) 1992-12-01
NO932722D0 (no) 1993-07-28
IL100791A0 (en) 1992-09-06
JPH06504541A (ja) 1994-05-26

Similar Documents

Publication Publication Date Title
US4636499A (en) Sulphenamides
CN1226292C (zh) 二氮杂环庚烷衍生物或其盐
CN1064268A (zh) 制备含有喹啉盐的药物组合物的方法
LT3914B (en) Compound with gastric acid inhibitory effect and process for its preparation
EP1861391B1 (en) Methods for preparing substituted sulfoxide compounds
JPS63501151A (ja) 新規な薬理活性化合物
CN109641884B (zh) 哌嗪衍生物、其药物组合物及其使用方法
CN1226236A (zh) 新化合物
EP1334971A1 (en) Benzimidazole compounds, process for producing the same and use thereof
CN1215399A (zh) 作为乙酰胆碱酯酶抑制剂及止痛药的靛红衍生物
PT89789B (pt) Processo de preparacao de novos derivados substituidos da quinolina e de composicoes farmaceuticas contendo tais derivados
JPH02503316A (ja) 化合物
MXPA05001168A (es) Sal de (s)-pantoprazol y sus hidratos.
JP2006500428A (ja) S−(−)−アムロジピンニコチネート及びその製造方法
IE81057B1 (en) Method of improving sleep
JPH01261374A (ja) 置換キノリン誘導体
EP0357403A2 (en) Substituted beta-diketones
HU211466A9 (en) Therapeutic benzazepine compounds
CN1617883A (zh) 苯并氮杂环庚三烯化合物的固体盐及其在制备药物化合物中的应用
JPH0692406B2 (ja) キサンチン誘導体、その製造方法およびそれらの医薬としての用途
CN1045207C (zh) 法呢基:蛋白质转移酶抑制剂作为抗癌剂
CH656382A5 (de) Sulfoxide, verfahren zu ihrer herstellung und ihre verwendung.
CA2147762A1 (en) Circulatory disorder improving agent
CS223895B2 (en) Method of making the n-l-allyl-2-pyrolidineylmethyl/-2-methoxy-4-amino-5-methylsulphamoylbenzenamides
JPH01261373A (ja) 置換キノリン誘導体

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C01 Deemed withdrawal of patent application (patent law 1993)
WD01 Invention patent application deemed withdrawn after publication