CN106387904B - A kind of composition and preparation method thereof, preparation and application - Google Patents
A kind of composition and preparation method thereof, preparation and application Download PDFInfo
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- CN106387904B CN106387904B CN201610867778.1A CN201610867778A CN106387904B CN 106387904 B CN106387904 B CN 106387904B CN 201610867778 A CN201610867778 A CN 201610867778A CN 106387904 B CN106387904 B CN 106387904B
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- 244000037364 Cinnamomum aromaticum Species 0.000 claims abstract description 48
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 claims abstract description 48
- 235000011347 Moringa oleifera Nutrition 0.000 claims abstract description 45
- 241001116389 Aloe Species 0.000 claims abstract description 40
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/482—Cassia, e.g. golden shower tree
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/62—Nymphaeaceae (Water-lily family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
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- A—HUMAN NECESSITIES
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/31—Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of composition and preparation method thereof, preparation and application, the composition includes the raw material of following weight percent: leaf of Moringa Ultramicro-powder 29.5% ~ 30.5%, cassia seed extract 29.5% ~ 30.5%, fructus cannabis powder 14.5% ~ 15.5%, emblic fine powder 12.5% ~ 13.5%, lotus leaf powder 6.5% ~ 7.5%, aloe Ultramicro-powder 4.5% ~ 5.5%.The significant effect that of the invention composition toxin expelling defaecation, is replenished the calcium, has the function of heat-clearing, ease constipation, liver improving eyesight of waking up, strengthen immunity while treat constipation, and strong protecting liver is accelerated to be metabolized.
Description
Technical field
The invention belongs to health-oriented products preparation technical fields, and in particular to a kind of composition and preparation method thereof, preparation with
Using.
Background technique
Due to the accelerating rhythm of life, the increase of pressure and undesirable living habit lead to the intracorporal toxin accumulation of body
Excessively, constipation is caused.Detoxicating intestine has become hot topic, and constipation is the natural enemy of modern, us is interfered normally to give birth to
Living, toxin caused by constipation excessively also affects the health of body, causes skin poor, and implication is not pure and fresh, strong influence I
Daily life.Nowadays many people are perplexed by constipation, are especially all women and the elderly.And city white collar women and
The elderly is also the group of people at high risk of calcium loss simultaneously, how to be replenished the calcium while treating constipation, and should study instantly
The problem of.
The product for the treatment of or improvement constipation currently on the market is various, but most of effects are not good enough, or are only " one
Rush down it ", it is palliative, or even have very big side effect, preparation method also has many deficiencies.
Summary of the invention
The first object of the present invention is to provide a kind of composition, and second is designed to provide a kind of preparation side of composition
Method, third are designed to provide a kind of preparation of composition, and the 4th is designed to provide a kind of application of composition.
The first object of the present invention is achieved in that the raw material including following weight percent: leaf of Moringa Ultramicro-powder
29.5% ~ 30.5%, cassia seed extract 29.5% ~ 30.5%, fructus cannabis powder 14.5% ~ 15.5%, emblic fine powder
12.5% ~ 13.5%, lotus leaf powder 6.5% ~ 7.5%, aloe Ultramicro-powder 4.5% ~ 5.5%.
The second object of the present invention is achieved in that the following steps that the preparation method includes:
1) it weighs: weighing leaf of Moringa Ultramicro-powder 29.5% ~ 30.5%, cassia seed extract 29.5% ~ 30.5%, fructus cannabis
Powder 14.5% ~ 15.5%, emblic fine powder 12.5% ~ 13.5%, lotus leaf powder 6.5% ~ 7.5%, aloe Ultramicro-powder 4.5% ~
5.5%, it is spare；
2) it mixes: the material weighed in step 1) is put into double paddle mixing machines, 95% edible wine is sprayed into mixing
Essence mixing 25 ~ 35 minutes, material with 95% edible alcohol weight ratio be 1:0.025, be uniformly mixed discharge, combined
Object.
What the third object of the present invention was realized in, the preparation is to be added pharmaceutically in the composition
The auxiliary material of receiving is prepared into capsule, tablet, powder, granule, liquid preparation, pill.
What the fourth object of the present invention was realized in, the composition is logical in preparation prevention/adjuvant treatment toxin expelling
Just, the application replenished the calcium in similar drug or health food.
Beneficial effects of the present invention:
1, the significant effect that of the invention composition toxin expelling defaecation, is replenished the calcium has the function of heat-clearing, ease constipation, liver improving eyesight of waking up,
Strengthen immunity while treating constipation, strong protecting liver accelerate metabolism.
2, raw material of the invention uses different preprocess methods, and leaf of Moringa and the defaecation of aloe raw material toxin expelling, enhancing are immunized
Power, effective ingredient of replenishing the calcium are high, thermal sensitivity is strong, and processing method of the invention is conducive to improve bioavilability；Cassia seed raw material has
Imitate that composition is low, quality is hard, so extract effective ingredient using alcohol-extracting technology of the invention, enhancing clears liver and improve vision, relax bowel and defecation
Effect；Emblic contains a large amount of fibers, dry difficult, and no matter processing cost, preparation processing Feasible degree etc. are all unfavorable, so adopting
Fine powder is extracted with method of the invention, is conducive to save, is conducive to preparation processing, is conducive to improve bioavilability；Fructus cannabis
Oily purging and intestine lubricating action is very strong, lotus leaf fiber toxin expelling effect is very strong, crushed direct ingredient preparation processing.This technique has
Beauty, flavouring taste conducive to product, enhancing replenish the calcium, promote the production of body fluid to quench thirst, toxin expelling aperient effects, mention product effective component concentration substantially
Height, mouthfeel are more preferable, effect is more significant.
3, effect effect of the leaf of Moringa Ultramicro-powder in this composition in raw material of the present invention: there is hypoglycemic, lipid-loweringing, drop
It presses, is antitumor, anti-oxidant, replenishing the calcium, defaecation, diuresis, improving the effects of sleep；The effect of cassia seed extract in this composition
Effect: have the effects that heat-clearing improving eyesight, toxin expelling defaecation；The effect of fructus cannabis powder effect in this composition: there is very strong profit
Intestines defecating feces excretion；Effect effect of the lotus leaf powder in this composition: it reduces fat, eliminate the effects of constipation, diuresis；Emblic essence
The effect of powder effect in this composition: there is anti-oxidant, liver protection, anti-inflammatory, clearing heat and cooling blood, food digesting stomach fortifying, cough-relieving of promoting the production of body fluid etc. to make
With；The effect of aloe Ultramicro-powder effect in this composition: let out under the anti-inflammatory, stomach invigorating of sterilization, heart tonifying promoting blood circulation, immunity anticancer, removing toxic substances,
The effects of analgesia, so that Moringa blade of the present invention is in good taste, replenish the calcium, promote the production of body fluid to quench thirst, toxin expelling defaecation and capable of enhancing is immunized
Power, while solving the problems, such as to replenish the calcium, toxin expelling defaecation treating both manifestation and root cause of disease.
4, the preparation method of Tablets uses Modern preparations technology, on formula: use poison expelling and beautifying, it is clearing heat and detoxicating,
It clears liver and improve vision, relax bowel and defecation, the raw material prescription collocation let out under stomach invigorating, product is made tablet, makes to process, take, save, carrying pole
For convenience, it is created condition to realize to be mass produced.
5, it between each raw material of the invention, cooperates, complements each other, inventive formulation combinatorial principle: raw material Moringa
Leaf and cassia seed, are toxin expelling defaecation of the present invention, strengthen immunity, the principal ingredients to play a decisive role of replenishing the calcium, but leaf of Moringa
Protein is very high, is easy to induce gout；Raw material cassia seed has the function of liver-nourishing and eyesight-improving enhancing diarrhea, promotes enterocinesia, still
Also the stimulation enteron aisle cold in nature that is easy induces enteritis, matches emblic fine powder and aloe so increasing, and emblic fine powder is mild-natured, has enhancing urine
Acid metabolic prevents pain wind action, the tartaric acid of emblic fine powder can with food digesting stomach fortifying and promote the production of body fluid, fructose can be with additional heat and member
Immunity can be enhanced in gas, natural vitamin C and hepatocuprein, and emblic fine powder not only counteracts the secondary of leaf of Moringa and makees
With, but also have the function of toxin expelling defaecation, anti-aging, anticancer, inhibit hepatitis B；Prebiotics in aloe raw material can be effective
Enteron aisle is protected, the side effect of cassia seed is not only counteracted, but also enterocinesia enhancing effect of ejecting poison can be promoted, promote this product
It absorbs and is conducive to fast onset；The advantageous enteral prods movement of ease constipation function in fructus cannabis；Lotus leaf is conducive to increase stool volume.It adopts
It mended, let out with various raw material effects, moistened, is auxiliary, attacked, is anti-and other effects and be collocated with each other；Extract ingredient and the direct ingredient of raw material combine, structure
At the formula of the invention optimized.
6, Moringa leaf raw material of the present invention replenish the calcium toxin expelling ingredient it is higher；Cassia seed raw material quality is hard, effective component ratio
It is lower, it extracts and is concentrated simultaneously at the extraction, seen off concentration at once after solute dissolution, alcohol is condensed into newly after being evaporated
Fresh solvent fills into extractor at any time, and the quantity of solvent of the amount of liquid and supplement seen off is equal, keeps liquid level equilibrium in tank, extraction process
In, solute is increasing in inspissator, and solute is constantly reduced in extractor, is increased solute dissolution gradient in extractor, is extracted
More complete, speed is faster.In the case that equivalent feeds intake, opposite water proposes much starch dissolution, independent gradation is concentrated again after extracting and needs
Time-consuming 10 hours, total solvent amount need 10 times, coal consumption need 2000 kilograms, power consumption need 600 degree, extract the method that yield only has 5%, originally
Method time-consuming only 5 hours, only 1100 kilograms of coal consumption, only 330 degree of power consumption, extracts yield up to 8% at only 6 times of total solvent amount；Fructus cannabis
The oily purging and intestine lubricating action of raw material is very strong；The wild unfavorable preservation of fresh fruit of fructus phyllanthi, and contain a large amount of fibers, it is dry difficult, no matter plus
Work cost, preparation processing Feasible degree etc. are all unfavorable, and extracting method of the present invention is conducive to save, is conducive to preparation processing, has
Conducive to raising bioavilability；The fiber toxin expelling effect of lotus leaf raw material is very strong, is crushed direct ingredient preparation processing；Aloe is former
Expect that toxin elimination and clot absorbing effect is very strong, extracting method of the invention, which can also promote to absorb, improves bioavilability, prominent product efficacy.
Specific embodiment
Below with reference to embodiment, the present invention is further illustrated, but the present invention is limited in any way,
Based on present invention teach that it is made it is any transform or replace, all belong to the scope of protection of the present invention.
Composition of the present invention, the raw material including following weight percent: leaf of Moringa Ultramicro-powder 29.5% ~
30.5%, cassia seed extract 29.5% ~ 30.5%, fructus cannabis powder 14.5% ~ 15.5%, emblic fine powder 12.5% ~
13.5%, lotus leaf powder 6.5% ~ 7.5%, aloe Ultramicro-powder 4.5% ~ 5.5%.
The preparation method of the leaf of Moringa Ultramicro-powder be leaf of Moringa is crushed with pulverizer, be sieved, obtain granularity be 80 ~
The leaf of Moringa fine powder of 120 mesh, then leaf of Moringa fine powder is added in micronizer in batches, keep revolving speed 200 ~ 300 turns/
Mir, rail pressure power is ground in 2 ~ 2.5kgf/cm2, air quantity is in 900 ~ 1300m3/ h, is pulverized, and obtaining granularity is 200 ~ 250 mesh
Leaf of Moringa Ultramicro-powder.
The extracting method of the cassia seed extract be include:
1) by cassia seed with pulverizer coarse crushing at the particle of 20 ~ 30 mesh, weighing is put into extractor, and 6 ~ 8 times of amounts are added
Concentration be 70 ~ 75% edible alcohol, impregnate 6 ~ 8 hours；
2) condenser and the steam heating for opening extractor, temperature reaches 75 DEG C, has boiled in tank, alcohol in tank to be extracted
When steam condensate is back in tank, the temperature in extractor is maintained at 73 ~ 78 DEG C boils and mention 30 minutes；
3) open the infusion valve between extractor and outer circulation inspissator, make extracting solution in extractor by valve into
Enter outer circulation inspissator, is then turned on the steam heating of outer circulation inspissator, makes the vaporized alcohol in extracting solution and return to extraction
Tank is condensed into liquid reflux to extractor by extractor condenser, while the cassia seed effective ingredient dissolved out in extractor is not
It is disconnected to be extracted in liquid band to outer circulation inspissator；During the extraction process, adjust infusion valve opening be one third at, extractor steam
Vapour heated pressure is maintained at 0.2 ~ 0.25MPa, inspissator steam heated pressure is maintained at 0.08 ~ 0.1MPa, condenser cooling water
Pressure is maintained at 0.3 ~ 0.4MPa, in this case sealing and circulating 3 hours；
4) condenser for opening outer circulation inspissator closes steam heating and the condenser of extractor, will be in extractor
Extracting solution is constantly put into outer circulation inspissator, starts simultaneously at recovered alcohol, and the temperature in outer circulation inspissator is maintained at 73 ~ 78
℃；After the extracting solution in extractor all discharges, the vaporized alcohol remained in cassia seed slag is gone out and recycled, extracting solution is worked as
When alcohol concentration in interior and slag is lower than 40%, stop recovered alcohol；
5) cassia seed slag is discharged, extracting solution is concentrated in vacuo, keep vacuum degree -0.07 ~ -0.075MPa, temperature 60 ~
65 DEG C, being concentrated into specific gravity is 1.2 ~ 1.25, receives cream, condensed cream is uniformly laid on baking tray, baking tray is placed on to the grill of rotation
On, keep vacuum degree -0.07 ~ -0.075MPa, carry out microwave drying under the conditions of 60 ~ 65 DEG C of temperature, it is dry to moisture 5% ~
Rewinding when 5.5%；Then dry condensed cream is crushed with pulverizer, is sieved, obtained the cassia seed that granularity is 80 ~ 120 mesh and mention
Take object.
The preparation method of the fructus cannabis powder be fructus cannabis is crushed with pulverizer, be sieved, obtain granularity be 80 mesh ~
The fructus cannabis powder of 120 mesh.
The preparation method of the emblic fine powder includes:
1) drum-type fruit washing machine is used after wild fresh fruit of fructus phyllanthi being rejected decayed fruit, impurity, cylinder revolving speed is maintained at 15 ~ 20
Rev/min, 5 ~ 10m of water spray flow3/ h, charging rate are maintained at 8 ~ 10 kg/minutes, the fresh fruit cleaned up, institute
The water stated is drinking water；
2) fruit crusher is used, charging rate is maintained at 5 ~ 8 kg/minutes, the fresh fruit cleaned up is broken for grain
Spend the particle of 2 ~ 5mm；
3) fruit pressafiner is used, revolving speed is maintained at 60 ~ 70 revs/min, particle is at the uniform velocity added, and charging rate is protected
It holds in 3 ~ 5 kg/minutes, pomace is discharged, underflow fruit juice is flowed out through strainer from bottom；
4) centrifuge is used, drum speed is maintained at 1000 ~ 1500 revs/min, and the underflow fruit juice that step 3) is obtained is even
Speed is added, and charging rate is maintained at 0.2 ~ 0.5 m3/ minute, the slag discharge isolated obtain fruit juice clear liquid；
5) the resulting fruit juice clear liquid of step 4) being spray-dried, high speed centrifugal atomization device revolving speed is maintained at 6000 ~
6500 revs/min, adjust air-supply and the air flow rate proportioning of air inducing, be maintained at spraying system between 50 ~ 200Pa of negative pressure, tower top into
Mouth temperature is maintained at 230 ~ 240 DEG C, and tower bottom outlet temperature is maintained at 110 ~ 120 DEG C, 10 beats/min of pulse rapping, stablizes screw rod
Feed rate is pumped at 80 ~ 100L/ minutes, is carried out continuously spray drying, obtains the emblic fine powder that granularity is 200 ~ 300 mesh.
The preparation method of the lotus leaf powder is to crush dried waterlily leaf with pulverizer, is sieved, and obtaining granularity is 80 mesh ~ 120
Purpose lotus leaf powder.
The preparation method of the aloe Ultramicro-powder is to crush the dry blade of aloe with pulverizer, is sieved, obtains granularity
For the aloe fine powder of 80 ~ 120 mesh, then aloe fine powder is intermittently added in 13.6KW micronizer, keep revolving speed 200 ~
300 turns/mir, grind rail pressure power in 2 ~ 2.5kgf/cm2, air quantity is in 900 ~ 1300m3/ h, is pulverized, and obtaining granularity is 200
The aloe Ultramicro-powder of ~ 250 mesh.
A kind of preparation method of composition, including following steps:
1) it weighs: weighing leaf of Moringa Ultramicro-powder 29.5% ~ 30.5%, cassia seed extract 29.5% ~ 30.5%, fructus cannabis
Powder 14.5% ~ 15.5%, emblic fine powder 12.5% ~ 13.5%, lotus leaf powder 6.5% ~ 7.5%, aloe Ultramicro-powder 4.5% ~
5.5%, it is spare；
2) it mixes: the material weighed in step 1) is put into double paddle mixing machines, 95% edible wine is sprayed into mixing
The weight ratio of essence mixing 25 ~ 35 minutes, the edible alcohol that straying quatity is material with 95% is 1:0.025, is uniformly mixed and discharges, obtains
To composition.
A kind of preparation of composition, the preparation are that the auxiliary material preparation pharmaceutically received is added in the composition
At capsule, tablet, powder, granule, liquid preparation, pill.
A kind of application of composition, the described application be the composition preparation prevention/adjuvant treatment toxin expelling defaecation,
The application replenished the calcium in similar drug or health food.
Embodiment 1
The preparation of leaf of Moringa Ultramicro-powder: leaf of Moringa is crushed with pulverizer, sieving, and it is thin to obtain the leaf of Moringa that granularity is 80 mesh
Then powder leaf of Moringa fine powder is added in micronizer in batches, keep revolving speed in 200 turns/mir, grind rail pressure power in 2kgf/
cm2, air quantity is in 900m3/ h, is pulverized, and the leaf of Moringa Ultramicro-powder that granularity is 200 mesh is obtained.
The preparation of cassia seed extract:
1) by cassia seed with pulverizer coarse crushing at the particle of 20 mesh, weighing is put into extractor, and the concentration of 6 times of amounts are added
For 70% edible alcohol, impregnate 8 hours；
2) condenser and the steam heating for opening extractor, temperature reaches 75 DEG C, has boiled in tank, alcohol in tank to be extracted
When steam condensate is back in tank, the temperature in extractor is maintained at 73 ~ 78 DEG C boils and mention 30 minutes；
3) open the infusion valve between extractor and outer circulation inspissator, make extracting solution in extractor by valve into
Enter outer circulation inspissator, is then turned on the steam heating of outer circulation inspissator, makes the vaporized alcohol in extracting solution and return to extraction
Tank is condensed into liquid reflux to extractor by extractor condenser, while the cassia seed effective ingredient dissolved out in extractor is not
It is disconnected to be extracted in liquid band to outer circulation inspissator；During the extraction process, adjust infusion valve opening be one third at, extractor steam
Vapour heated pressure is maintained at 0.2MPa, inspissator steam heated pressure is maintained at 0.08MPa, condenser cooling water pressure is maintained at
0.3MPa, makes in extractor that material is all flooded by alcohol liquid during the extraction process, inspissator liquid level is maintained at visor two and divides
One of place, steam heating amount the vapor-liquid equilibrium such as do not increase, sealing and circulating 3 hours in this case；
4) condenser for opening outer circulation inspissator closes steam heating and the condenser of extractor, will be in extractor
Extracting solution is constantly put into outer circulation inspissator, starts simultaneously at recovered alcohol, and the temperature in outer circulation inspissator is maintained at 73 ~ 78
℃；After the extracting solution in extractor all discharges, the vaporized alcohol remained in cassia seed slag is gone out and recycled, extracting solution is worked as
When alcohol concentration in interior and slag is lower than 40%, stop recovered alcohol；
5) cassia seed slag is discharged, extracting solution is concentrated in vacuo, keep vacuum degree in -0.07MPa, temperature 60 C, concentration
It is 1.2 to specific gravity, receives cream, condensed cream is uniformly laid on baking tray, baking tray is placed on the grill of rotation, keeps vacuum degree-
Carry out microwave drying under the conditions of 0.07MPa, temperature 60 C, it is dry to moisture 5% when rewinding；Then by dry condensed cream powder
Broken machine crushes, sieving, obtains the cassia seed extract that granularity is 80 mesh.
The preparation of fructus cannabis powder: fructus cannabis is crushed with pulverizer, sieving, obtains the fructus cannabis powder that granularity is 80 mesh.
The preparation of emblic fine powder:
1) drum-type fruit washing machine is used after wild fresh fruit of fructus phyllanthi being rejected decayed fruit, impurity, cylinder revolving speed is maintained at 15 revs/min
Clock, water spray flow 5m3/ h, charging rate are maintained at 8 kg/minutes, the fresh fruit cleaned up, and the water is to drink
Water；
2) fruit crusher is used, charging rate is maintained at 5 kg/minutes, the fresh fruit cleaned up is broken for granularity
The particle of 2mm；
3) fruit pressafiner is used, revolving speed is maintained at 60 revs/min, particle is at the uniform velocity added, and charging rate is kept
In 3 kg/minutes, pomace is discharged, underflow fruit juice is flowed out through strainer from bottom；
4) centrifuge is used, drum speed is maintained at 1000 revs/min, the underflow fruit juice that step 3) obtains at the uniform velocity is added
Enter, charging rate is maintained at 0.2m3/ minute, the slag discharge isolated obtain fruit juice clear liquid；
5) the resulting fruit juice clear liquid of step 4) is spray-dried, high speed centrifugal atomization device revolving speed be maintained at 6000 turns/
Minute, the air flow rate proportioning of air-supply with air inducing is adjusted, is maintained at spraying system between negative pressure 50Pa, tower top inlet temperature is maintained at
230 DEG C, tower bottom outlet temperature is maintained at 110 DEG C, 10 beats/min of pulse rapping, stablizes screw pump feed rate at 80L/ minutes,
It is carried out continuously spray drying, obtains the emblic fine powder that granularity is 200 mesh.
The preparation of lotus leaf powder: dried waterlily leaf is crushed with pulverizer, sieving, obtains the lotus leaf powder that granularity is 80 mesh.
The preparation of aloe Ultramicro-powder: the dry blade of aloe is crushed with pulverizer, is sieved, obtains the aloe that granularity is 80 mesh
Then aloe fine powder is intermittently added in 13.6KW micronizer by fine powder, revolving speed is kept to exist in 200 turns/mir, stone roller rail pressure power
2kgf/cm2, air quantity is in 900m3/ h, is pulverized, and the aloe Ultramicro-powder that granularity is 200 mesh is obtained.
The preparation of the tablet of composition:
1) leaf of Moringa Ultramicro-powder 29.5%, cassia seed extract 30.5%, fructus cannabis powder 14.5%, emblic fine powder are taken
13.5%, lotus leaf powder 6.5%, aloe Ultramicro-powder 5.5%, it is spare；2) material weighed in step 1) is put into double paddle mixing machines
Interior, 95% edible alcohol that 2kg is sprayed into mixing mixes 25 minutes, is uniformly mixed discharging, obtains composition；3) by described group
Polymer mixtures material is added in the oscillating granulator of operating, produces wet granular, spare；4) wet granular is baked with sanitation-grade stainless steel
Disk installs, and 2 kilograms of every disk is uniformly paved with disk, is put into vacuum oven, closed chamber door, opens vacuum extremely -0.065MPa,
Steam is slowly opened, temperature is controlled at 60 DEG C, is discharged when being no more than 7% within dry 2 hours to moisture, spare；5) dried object
Expect that particle is added in pelletizing machine, filters out the particle of even particle size, it is spare；6) whole grain good particle rotary pelleting machine pressure
Piece, standard circular piece, slice weight 0.5g, the sieving polishing of piece is to interior packet；7) after the tablet pressed carries out irradiation sterilization, bottling machine is used
Bottling, 100 every bottle.
Case 1: Lee XX, female, 53 years old, frequent constipation, difficult defecation.Lee XX adheres to taking the system of the embodiment of the present invention 1 daily
It is standby to obtain Moringa blade, constipation symptom mitigation after two weeks is taken, constipation symptom disappears after 3 months.
Embodiment 2
Leaf of Moringa Ultramicro-powder: leaf of Moringa is crushed with pulverizer, is sieved, the leaf of Moringa fine powder that granularity is 120 mesh is obtained,
Then leaf of Moringa fine powder is added in micronizer in batches, keeps revolving speed in 300 turns/mir, grinds rail pressure power in 2.5kgf/
cm2, air quantity is in 1300m3/ h, is pulverized, and the leaf of Moringa Ultramicro-powder that granularity is 250 mesh is obtained.
The preparation of cassia seed extract:
1) by cassia seed with pulverizer coarse crushing at the particle of 30 mesh, weighing is put into extractor, and the concentration of 8 times of amounts are added
For 75% edible alcohol, impregnate 8 hours；
2) condenser and the steam heating for opening extractor, temperature reaches 75 DEG C, has boiled in tank, alcohol in tank to be extracted
When steam condensate is back in tank, the temperature in extractor is maintained at 73 ~ 78 DEG C boils and mention 30 minutes；
3) open the infusion valve between extractor and outer circulation inspissator, make extracting solution in extractor by valve into
Enter outer circulation inspissator, is then turned on the steam heating of outer circulation inspissator, makes the vaporized alcohol in extracting solution and return to extraction
Tank is condensed into liquid reflux to extractor by extractor condenser, while the cassia seed effective ingredient dissolved out in extractor is not
It is disconnected to be extracted in liquid band to outer circulation inspissator；During the extraction process, adjust infusion valve opening be one third at, extractor steam
Vapour heated pressure is maintained at 0.25MPa, inspissator steam heated pressure is maintained at 0.1MPa, condenser cooling water pressure is maintained at
0.4MPa, makes in extractor that material is all flooded by alcohol liquid during the extraction process, inspissator liquid level is maintained at visor two and divides
One of place, steam heating amount the vapor-liquid equilibrium such as do not increase, sealing and circulating 3 hours in this case；
4) condenser for opening outer circulation inspissator closes steam heating and the condenser of extractor, will be in extractor
Extracting solution is constantly put into outer circulation inspissator, starts simultaneously at recovered alcohol, and the temperature in outer circulation inspissator is maintained at 73 ~ 78
℃；After the extracting solution in extractor all discharges, the vaporized alcohol remained in cassia seed slag is gone out and recycled, extracting solution is worked as
When alcohol concentration in interior and slag is lower than 40%, stop recovered alcohol；
5) cassia seed slag is discharged, extracting solution is concentrated in vacuo, keep vacuum degree in 65 DEG C of -0.075MPa, temperature, concentration
It is 1.25 to specific gravity, receives cream, condensed cream is uniformly laid on baking tray, baking tray is placed on the grill of rotation, keeps vacuum degree-
0.075MPa, carry out microwave drying under the conditions of 65 DEG C of temperature, it is dry to moisture 5.5% when rewinding；Then by dry condensed cream
It is crushed, is sieved with pulverizer, obtain the cassia seed extract that granularity is 120 mesh.
The preparation of fructus cannabis powder: fructus cannabis is crushed with pulverizer, sieving, obtains the fructus cannabis powder that granularity is 120 mesh.
The preparation of emblic fine powder:
1) drum-type fruit washing machine is used after wild fresh fruit of fructus phyllanthi being rejected decayed fruit, impurity, cylinder revolving speed is maintained at 20 revs/min
Clock, water spray flow 10m3/ h, charging rate are maintained at 10 kg/minutes, the fresh fruit cleaned up, and the water is drink
Use water；
2) fruit crusher is used, charging rate is maintained at 8 kg/minutes, the fresh fruit cleaned up is broken for granularity
The particle of 5mm；
3) fruit pressafiner is used, revolving speed is maintained at 70 revs/min, particle is at the uniform velocity added, and charging rate is kept
In 5 kg/minutes, pomace is discharged, underflow fruit juice is flowed out through strainer from bottom；
4) centrifuge is used, drum speed is maintained at 1500 revs/min, the underflow fruit juice that step 3) obtains at the uniform velocity is added
Enter, charging rate is maintained at 0.5 m3/ minute, the slag discharge isolated obtain fruit juice clear liquid；
5) the resulting fruit juice clear liquid of step 4) is spray-dried, high speed centrifugal atomization device revolving speed be maintained at 6500 turns/
Minute, the air flow rate proportioning of air-supply with air inducing is adjusted, is maintained at spraying system between negative pressure 200Pa, tower top inlet temperature is kept
At 240 DEG C, tower bottom outlet temperature is maintained at 120 DEG C, 10 beats/min of pulse rapping, stablizes screw pump feed rate at 100L/ points
Clock is carried out continuously spray drying, obtains the emblic fine powder that granularity is 300 mesh.
The preparation of lotus leaf powder: dried waterlily leaf is crushed with pulverizer, sieving, obtains the lotus leaf powder that granularity is 120 mesh.
The preparation of aloe Ultramicro-powder: the dry blade of aloe is crushed with pulverizer, is sieved, obtains the reed that granularity is 120 mesh
Then aloe fine powder is intermittently added in 13.6KW micronizer by luxuriant growth fine powder, keep revolving speed in 300 turns/mir, grind rail pressure power
In 2.5kgf/cm2, air quantity is in 1300m3/ h, is pulverized, and the aloe Ultramicro-powder that granularity is 250 mesh is obtained.
The preparation method of the tablet of composition:
1) leaf of Moringa Ultramicro-powder 30.5%, cassia seed extract 29.5%, fructus cannabis powder 15.5%, emblic fine powder are taken
12.5%, lotus leaf powder 7.5%, aloe Ultramicro-powder 4.5%, it is spare；2) material weighed in step 1) is put into double paddle mixing machines
It is interior, while mixing while sprays into 95% edible alcohol mix 35 minutes, material and 95% edible alcohol weight ratio be 1:
0.025, it is uniformly mixed discharging, obtains composition；3) the composition mixture material is added in the oscillating granulator of operating, system
Wet granular out, it is spare；4) wet granular is installed with sanitation-grade stainless steel baking tray, 2 kilograms of every disk is uniformly paved with disk, is put into true
In empty drying box, closed chamber door opens vacuum to -0.075MPa, slowly opens steam, temperature is controlled at 65 DEG C, and dry 2.5 is small
When, drying to moisture discharges when being no more than 7%, spare；5) dried material particles are added in pelletizing machine, and it is big to filter out particle
Small uniform particle, it is spare；6) whole grain good particle rotary pelleting machine tabletting, standard circular piece, slice weight 0.5g, the sieving of piece
Polishing is to interior packet；7) it after the tablet pressed carries out irradiation sterilization, is bottled with bottling machine, 100 every bottle.
Case 2: Lee XX, male, 72 years old, retired professor was perplexed by the problem of constipation always.Lee XX adheres to taking this hair daily
Bright embodiment 2 is prepared 5, Moringa blade, and constipation problem is substantially improved, health.
Embodiment 3
The preparation of leaf of Moringa Ultramicro-powder: the outsourcing leaf of Moringa dried object of quality inspection qualification is weighed, omnipotent with 5.5KW stainless steel
Pulverizer crushing sieves with 100 mesh sieve, and obtains the leaf of Moringa fine powder that granularity is 100 mesh, is then intermittently added leaf of Moringa fine powder
In the pulverizing chamber of 13.6KW micronizer, keeps revolving speed in 250 turns/mir, grinds rail pressure power in 2.2kgf/cm2, air quantity exists
1000m3Ultramicro grinding operation is carried out under/h condition, receives powder with powder collector splicing bucket, obtains the leaf of Moringa ultra micro that granularity is 220 mesh
Powder.
The preparation of cassia seed extract: by the outsourcing cassia seed raw material of quality inspection qualification with the coarse crushing of 5.5KW pulverizer at 25 mesh
Particle, weighing put into extractor, be added 6 times amount concentration be 70% edible alcohol, impregnate 8 hours.It opens and extracts
Tank condenser recirculated cooling water opens the heating of extractor steam, reaches 75 DEG C to temperature, has boiled in tank, alcohol steam condensation
When liquid is back in tank, temperature is maintained at 73-78 DEG C of independent boil and mentions 30 minutes.Open extractor connection outer circulation inspissator infusion
Valve, while the valve of outer circulation inspissator boil-off gas connection extractor condenser is opened, open the heating of outer circulation inspissator
Steam, the vaporized alcohol in alcohol extract for carrying out extractor conveying pass through extractor condenser at steam to extractor condenser
It is condensed into liquid reflux to extractor；The pueraria lobata effective ingredient dissolved out in extractor is constantly brought by alcohol liquid to concentration in time
In device.Adjust infusion valve opening, extractor and inspissator steam heating amount, cooling water inflow, it is ensured that material is extracting in extractor
It is all flooded by alcohol liquid in the process, the vapour such as inspissator liquid level is maintained at visor half, steam heating amount does not increase
Liquid balances, in this case closed dynamic circulation 3 hours.Then it opens outer circulation concentration condenser connecting valve and outer circulation is dense
Contracting condenser recirculated cooling water closes extractor steam and connection extractor condenser valve, by the extracting solution one in extractor
It is temporary to be partially placed into storage tank, another part is constantly put into outer circulation inspissator, opens gas steam heating recovery alcohol, and temperature is maintained at
73-78 DEG C, tapping and recovered alcohol carry out simultaneously.After the liquid in extractor all discharges, opens bottom in extractor and steam
Vapour 2 hours, temperature was maintained at 73-78 DEG C, will remain in the vaporized alcohol in cassia seed slag and goes out to after extracting condenser condensation to return
It receives, the recycling of alcohol carries out simultaneously in alcohol and extracting solution in cassia seed slag.It is low with the alcohol concentration recycled in slag in extracting solution
When 40%, stop recovered alcohol, slag discharge.Extracting solution starts to be concentrated in vacuo, and keeps vacuum degree in -0.072MPa, temperature 62
DEG C, after liquid all adds, being concentrated into specific gravity is 1.2, receives cream.Condensed cream is uniformly laid on baking tray, and it is public that each baking tray is laid with 4
Jin, each baking tray is placed on the grill of rotation, keeps vacuum degree -0.072MPa, carries out microwave drying under the conditions of 62 DEG C of temperature, does
It is dry to moisture 5% when rewinding.Dry cassia seed alcohol cream is crushed with 5.5KW stainless steel Universalpulverizer, sieves with 100 mesh sieve, obtain
It is the cassia seed extract of 100 mesh to granularity.
The preparation of fructus cannabis powder: fructus cannabis is crushed with pulverizer, sieving, and obtaining granularity is 80 mesh ~ 120 mesh fructus cannabis
Powder.
The preparation of emblic fine powder:
Addition stainless steel high position hopper is weighed after the wild fresh fruit of fructus phyllanthi of the outsourcing of quality inspection qualification is rejected decayed fruit, impurity
In, 5KW drum-type fruit washing machine is opened, water sprinkler system is drunk in unlatching, and after working well, cylinder revolving speed is maintained at 18 revs/min, water
Spray flow 8m3/ h fresh fruit of fructus phyllanthi at the uniform velocity fruit be continuously added to rotation, spray water fruit washing machine helix drum in, a side continuously into
Material, another party's continuous discharge, charging rate are maintained at 9 kg/minutes, and the fresh fruit of wash clean is promoted by conveyer belt to stainless steel
It is stored in high-order hopper；Start 5.5KW fruit crusher, the fresh fruit cleaned up is at the uniform velocity added, and charging rate is maintained at 6 public affairs
Fresh fruit is broken for the particle of granularity 4mm by jin/minute, is promoted by conveyer belt into stainless steel high position hopper and is stored；Starting
7.5KW fruit pressafiner, revolving speed are maintained at 65 revs/min, particle are at the uniform velocity added, charging rate is maintained at 4 kilograms/point
Clock, pomace discharge from the other end and discharge, and fruit juice is flowed out through strainer from bottom, are pumped into the storage of stainless steel head tank through food-grade underflow
It deposits；Start 10KW automatic discharge centrifuge, drum speed is maintained at 1200 revs/min, underflow fruit juice is at the uniform velocity added, charging speed
Degree is maintained at 0.4 m3/ minute, the slag discharge isolated, it is temporary that fruit juice clear liquid fruit juice pump is delivered to stainless steel storage tank；Successively
Start the systems such as the air-supply of 120KW spray drying tower, air inducing, heating, pulse rapping, high speed centrifugation atomization, drinking water is through screw pump
It is sent into high speed centrifugal atomization device, debugs each parameter of spraying system, it is ensured that high speed centrifugal atomization device revolving speed is maintained at 6200 revs/min
Clock adjusts the air flow rate proportionings such as air-supply, air inducing, is maintained at spraying system between negative pressure 100Pa, tower top inlet temperature is maintained at
235 DEG C, tower bottom outlet temperature is maintained at 115 DEG C, 10 beats/min of pulse rapping, stablizes screw pump feed rate at 90L/ minutes,
Ensure that water spraying atomization all can be steam raising 30 minutes, changes water inlet into charging fruit juice by spraying and be sprayed, under the above conditions continuously
Fruit juice spray drying is carried out, it is primary in clean area powder collector rewinding per hour, obtain the emblic fine powder that granularity is 250 mesh.
The preparation method of lotus leaf powder is to crush dried waterlily leaf with pulverizer, is sieved, and the lotus leaf powder that granularity is 100 mesh is obtained.
The preparation method of aloe Ultramicro-powder is to weigh the aloe dried object of quality inspection qualification, with the omnipotent powder of 5.5KW stainless steel
Broken machine crushes, and sieves with 100 mesh sieve, and obtaining granularity is then aloe fine powder is intermittently added 13.6KW ultramicro grinding by 100 targeted fine powders
In the pulverizing chamber of machine, keeps revolving speed in 250 turns/mir, grinds rail pressure power in 2.2kgf/cm2, air quantity is in 1000m3It is carried out under/h condition
Operation is pulverized, receives powder with powder collector splicing bucket, obtains the aloe Ultramicro-powder that granularity is 220 mesh.
The preparation of composition
1) it weighs: weighing leaf of Moringa Ultramicro-powder 30%, cassia seed extract 30%, fructus cannabis powder 15%, emblic fine powder
13%, lotus leaf powder 7%, aloe Ultramicro-powder 5%, it is spare；
2) it mixes: the material weighed in step 1) is put into double paddle mixing machines, 95% edible wine is sprayed into mixing
The weight ratio of essence mixing 30 minutes, the edible alcohol that straying quatity is material with 95% is 1:0.025, is uniformly mixed and discharges, obtains
Composition.
The auxiliary material pharmaceutically received is added in the composition and is prepared into tablet.
Case 3: Zhao XX, female, 23 years old, body immunity was low, liable to illness.Zhao XX adheres to taking the embodiment of the present invention daily
3 are prepared 5, Moringa blade, continuously take 3 months, and immunity significantly improves, and sick number substantially reduces, and body is strong
Health feels energetic.
Embodiment 4
1) it weighs: weighing leaf of Moringa Ultramicro-powder 29.5%, cassia seed extract 29.5%, fructus cannabis powder 14.5%, emblic
Sub- fine powder 13.5%, lotus leaf powder 7.5%, aloe Ultramicro-powder 5.5%, it is spare；
2) it mixes: the material weighed in step 1) is put into double paddle mixing machines, 95% edible wine is sprayed into mixing
The weight ratio of essence mixing 28 minutes, the edible alcohol that straying quatity is material with 95% is 1:0.025, is uniformly mixed and discharges, obtains
Composition.
The auxiliary material pharmaceutically received is added in the composition and is prepared into capsule.
The composition can answer in preparation prevention/adjuvant treatment toxin expelling defaecation, replenish the calcium similar drug or health food
With.
Embodiment 5
1) it weighs: weighing leaf of Moringa Ultramicro-powder 30.5%, cassia seed extract 30.5%, fructus cannabis powder 15.5%, emblic
Sub- fine powder 12.5%, lotus leaf powder 6.5%, aloe Ultramicro-powder 4.5%, it is spare；
2) it mixes: the material weighed in step 1) is put into double paddle mixing machines, 95% edible wine is sprayed into mixing
The weight ratio of essence mixing 32 minutes, the edible alcohol that straying quatity is material with 95% is 1:0.025, is uniformly mixed and discharges, obtains
Composition.
The auxiliary material pharmaceutically received is added in the composition and is prepared into pill.
The composition can answer in preparation prevention/adjuvant treatment toxin expelling defaecation, replenish the calcium similar drug or health food
With.
Claims (8)
1. a kind of composition, it is characterised in that composition for toxin expelling defaecation, replenish the calcium, composition by following weight percent original
Material is made: leaf of Moringa Ultramicro-powder 29.5% ~ 30.5%, cassia seed extract 29.5% ~ 30.5%, fructus cannabis powder 14.5% ~ 15.5%, remaining
Sweet sub- fine powder 12.5% ~ 13.5%, lotus leaf powder 6.5% ~ 7.5%, aloe Ultramicro-powder 4.5% ~ 5.5%；
The preparation method of the leaf of Moringa Ultramicro-powder is to crush leaf of Moringa with pulverizer, is sieved, and obtaining granularity is 80 ~ 120 mesh
Leaf of Moringa fine powder, then leaf of Moringa fine powder is added in micronizer in batches, keep revolving speed 200 ~ 300 turns/min,
Rail pressure power is ground in 2 ~ 2.5kgf/cm2, air quantity is in 900 ~ 1300m3/ h, is pulverized, and obtaining granularity is that 200 ~ 250 purposes are peppery
The wooden leaf Ultramicro-powder；
The preparation method of the cassia seed extract includes:
1) by cassia seed with pulverizer coarse crushing at the particle of 20 ~ 30 mesh, weighing is put into extractor, and the dense of 6 ~ 8 times of amounts is added
The edible alcohol that degree is 70 ~ 75% impregnates 6 ~ 8 hours；
2) condenser and the steam heating for opening extractor, temperature reaches 75 DEG C, has boiled in tank, alcohol steam in tank to be extracted
When condensate liquid is back in tank, the temperature in extractor is maintained at 73 ~ 78 DEG C boils and mention 30 minutes；
3) the infusion valve between extractor and outer circulation inspissator is opened, enters the extracting solution in extractor by valve outer
Inspissator is recycled, the steam heating of outer circulation inspissator is then turned on, makes the vaporized alcohol in extracting solution and return to extractor, lead to
It crosses extractor condenser and is condensed into liquid reflux to extractor, while the cassia seed effective ingredient dissolved out in extractor is constantly mentioned
It takes in liquid band to outer circulation inspissator；During the extraction process, adjust infusion valve opening be one third at, extractor steam heating
Pressure is maintained at 0.2 ~ 0.25MPa, inspissator steam heated pressure is maintained at 0.08 ~ 0.1MPa, condenser cooling water pressure is kept
In 0.3 ~ 0.4MPa, sealing and circulating 3 hours in this case；
4) condenser for opening outer circulation inspissator closes steam heating and the condenser of extractor, by the extraction in extractor
Liquid is constantly put into outer circulation inspissator, starts simultaneously at recovered alcohol, and the temperature in outer circulation inspissator is maintained at 73 ~ 78 DEG C；
After the extracting solution in extractor all discharges, the vaporized alcohol remained in cassia seed slag is gone out and recycled, when in extracting solution
When being lower than 40% with the alcohol concentration in slag, stop recovered alcohol；
5) cassia seed slag is discharged, extracting solution is concentrated in vacuo, keep vacuum degree in -0.07 ~ -0.075MPa, temperature 60 ~ 65
DEG C, being concentrated into specific gravity is 1.2 ~ 1.25, cream is received, condensed cream is uniformly laid on baking tray, baking tray is placed on the grill of rotation,
Keep vacuum degree -0.07 ~ -0.075MPa, carry out microwave drying under the conditions of 60 ~ 65 DEG C of temperature, it is dry to moisture 5% ~ 5.5% when receive
Material；Then dry condensed cream is crushed with pulverizer, is sieved, obtain the cassia seed extract that granularity is 80 ~ 120 mesh.
2. composition according to claim 1, it is characterised in that the preparation method of the fructus cannabis powder is to use fructus cannabis
Pulverizer crushes, sieving, and obtaining granularity is 80 mesh ~ 120 mesh fructus cannabis powder.
3. composition according to claim 1, it is characterised in that the preparation method of the emblic fine powder includes:
1) drum-type fruit washing machine is used after wild fresh fruit of fructus phyllanthi being rejected decayed fruit, impurity, cylinder revolving speed is maintained at 15 ~ 20 revs/min
Clock, 5 ~ 10m of water spray flow3/ h, charging rate are maintained at 8 ~ 10 kg/minutes, the fresh fruit cleaned up, the water
For drinking water；
2) use fruit crusher, charging rate is maintained at 5 ~ 8 kg/minutes, by the fresh fruit cleaned up be broken for granularity 2 ~
The particle of 5mm；
3) fruit pressafiner is used, revolving speed is maintained at 60 ~ 70 revs/min, particle is at the uniform velocity added, charging rate is maintained at
3 ~ 5 kg/minutes, pomace is discharged, and underflow fruit juice is flowed out through strainer from bottom；
4) centrifuge is used, drum speed is maintained at 1000 ~ 1500 revs/min, the underflow fruit juice that step 3) obtains at the uniform velocity is added
Enter, charging rate is maintained at 0.2 ~ 0.5m3/ minute, the slag discharge isolated obtain fruit juice clear liquid；
5) the resulting fruit juice clear liquid of step 4) is spray-dried, high speed centrifugal atomization device revolving speed be maintained at 6000 ~ 6500 turns/
Minute, the air flow rate proportioning of air-supply with air inducing is adjusted, so that spraying system is maintained at 50 ~ 200Pa of negative pressure, tower top inlet temperature is maintained at
230 ~ 240 DEG C, tower bottom outlet temperature is maintained at 110 ~ 120 DEG C, 10 beats/min of pulse rapping, stablizes screw pump feed rate and exists
80 ~ 100L/ minutes, it is carried out continuously spray drying, obtains the emblic fine powder that granularity is 200 ~ 300 mesh.
4. composition according to claim 1, it is characterised in that the preparation method of the lotus leaf powder is by dried waterlily leaf powder
Broken machine crushes, sieving, and obtaining granularity is 80 mesh ~ 120 mesh lotus leaf powder.
5. composition according to claim 1, it is characterised in that the preparation method of the aloe Ultramicro-powder is to do aloe
Dry blade is crushed with pulverizer, sieving, is obtained the aloe fine powder that granularity is 80 ~ 120 mesh, is then intermittently added aloe fine powder super
In atomizer, keeps revolving speed in 200 ~ 300 turns/min, grinds rail pressure power in 2 ~ 2.5kgf/cm2, air quantity is in 900 ~ 1300m3/ h,
It is pulverized, obtains the aloe Ultramicro-powder that granularity is 200 ~ 250 mesh.
6. a kind of preparation method of the composition any according to claim 1 ~ 5, it is characterised in that the preparation method includes
Following steps:
1) weigh: weigh leaf of Moringa Ultramicro-powder 29.5% ~ 30.5%, cassia seed extract 29.5% ~ 30.5%, fructus cannabis powder 14.5% ~
15.5%, emblic fine powder 12.5% ~ 13.5%, lotus leaf powder 6.5% ~ 7.5%, aloe Ultramicro-powder 4.5% ~ 5.5%, it is spare；
2) it mixes: the material weighed in step 1) is put into double paddle mixing machines, 95% edible alcohol mixing is sprayed into mixing
25 ~ 35 minutes, material and 95% edible alcohol weight ratio be 1:0.025, be uniformly mixed discharging, obtain composition.
7. a kind of preparation of the composition any according to claim 1 ~ 5, it is characterised in that medicine is added in the composition
The auxiliary material received on is prepared into capsule, tablet, powder, granule, liquid preparation or pill.
8. a kind of composition any according to claim 1 ~ 5 is in preparation prevention or adjuvant treatment toxin expelling defaecation, class of replenishing the calcium medicine
Application in product or health food.
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| CN112353850A (en) * | 2020-07-28 | 2021-02-12 | 深圳市老年医学研究所 | Medicated diet food product composition for hyperlipidemia and fatty liver and preparation method thereof |
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| CN102217758A (en) * | 2011-04-30 | 2011-10-19 | 楚雄州百草岭药业发展有限公司 | Emblic leafflower fruit capsule and preparation method thereof |
| CN102835664A (en) * | 2012-09-29 | 2012-12-26 | 楚雄州百草岭药业发展有限公司 | Phyllanthus emblica fine powder containing high-activity superoxide dismutase and preparation method |
| CN103535811B (en) * | 2013-10-23 | 2015-04-08 | 桂林丰润莱生物科技有限公司 | Stasis removing, collaterals dredging and breast beautifying drink and preparation method thereof |
| CN104547045B (en) * | 2014-12-25 | 2017-07-04 | 福州嘉佑化学科技有限公司 | A kind of leaf of Moringa compound granules and preparation method thereof |
| CN104643085A (en) * | 2015-03-11 | 2015-05-27 | 桓仁满族自治县益仁堂中药材有限公司 | Multivitamin granules containing cordyceps sinensis |
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