CN105688146A - Healthcare capsule for improving sleeping quality - Google Patents

Healthcare capsule for improving sleeping quality Download PDF

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Publication number
CN105688146A
CN105688146A CN201610119676.1A CN201610119676A CN105688146A CN 105688146 A CN105688146 A CN 105688146A CN 201610119676 A CN201610119676 A CN 201610119676A CN 105688146 A CN105688146 A CN 105688146A
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caprae seu
seu ovis
placenta caprae
capsule
unqualified
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CN201610119676.1A
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许五妮
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Individual
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48Reproductive organs
    • A61K35/50Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/60Fish, e.g. seahorses; Fish eggs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02Algae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/39Convolvulaceae (Morning-glory family), e.g. bindweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/40Cornaceae (Dogwood family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/538Schizonepeta
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/58Meliaceae (Chinaberry or Mahogany family), e.g. Azadirachta (neem)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/82Theaceae (Tea family), e.g. camellia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/87Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8962Allium, e.g. garden onion, leek, garlic or chives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Abstract

The invention provides a healthcare capsule for improving sleeping quality. The healthcare capsule is prepared from, by weight, 50 g of banana skin, 60 g of arabian jasmine flowers, 30 g of chinese toon leaves, 60 g of rape flowers, 100 g of figs, 40 g of sheep placenta powder, 20 g of pulp of dogwood fruit, 20 g of eel bone, 10 g of fresh ginger, 10 g of wild grape leaves, 10 g of wild rice shoot leaves, 10 g of herba schizonepetae, 10 g of peanut sprouts, 10 g of white tea, 10 g of seaweed, 8 g of water spinach, 8 g of bitter gourd, 10 g of black fungus, 8 g of onion flower, 10 g of broccoli and 10 g of glutinous rice roots. Aiming at the clinical manifestation of people with subhealth and chronic fatigue syndrome, with determination of etiologic factors based on differentiation and syndrome differentiation and treatment as principles, essence of traditional chinese medicinal materials is adopted to supplement liver and kidney deficiency and tonify heart and lung qi, and the healthcare capsule can eliminate body fatigue, improve sleeping quality and enable people to keep abundant energy in high-speed life of modern cities.

Description

A kind of health-caring capsule improving sleep quality
Technical field
The present invention relates to health product technology field, be specifically related to a kind of health-caring capsule improving sleep quality。
Background technology
Along with the quickening of people's rhythm of life, and the pressure from aspects such as society, families, make people be in the fatigue state of a kind of anxiety within and mentally, in the course of time, arise that insomnia, dizziness, headache, the symptom such as forgetful, weak。The life of patient, work, study and inter personal contact are all produced impact by these symptoms, so that vicious cycle, secondary anxiety, depression, hypochondriasis and fear etc., bring the misery on huge body & mind to patient。
Adopting some Western medicine tranquilizer clinically now, such as treatment insomnias such as stable, chlorpromazine, secobarbitals, along with course of disease prolongation, dose is also continuously increased, or needs to change the calm medicine that effect is higher more。The control of Western medicine opioid therapy insomnia simply removing food stagnancy or pressure sleep, it is impossible to improve sleep quality, and toxic and side effects neural, internal organs are that people have common recognition morning by chemistry tranquilizer。Also having some Chinese patent medicines clinically now, such as BUXIN DAN, Pill of Magnetitum and Cinnabari, Cinnabar Sedative Pill etc., but they obtain gratifying effect in curative effect。
Summary of the invention
The technical problem to be solved is in that to provide a kind of health-caring capsule improving sleep quality, it is possible to eliminate physical fatigue, health invigorating, makes people keep abundant energy in the high-speed domestic of modern city。
The technical problem to be solved realizes by the following technical solutions:
A kind of health-caring capsule improving sleep quality, is made up of the component of following weight: Pericarpium Musae 50g, Flos Jasmini Sambac 60g, Folium toonae sinensis 30g, rape flower 60g, Fructus Fici 100g, Placenta caprae seu ovis powder 40g, Fructus Corni 20g, Os Monopteri albi 20g, ocean Rhizoma Zingiberis Recens 10g, Radix vitis romanetii leaf 10g, cane shoots leaves 10g, Herba Schizonepetae 10g, peanut sprout 10g, Ramulus et Folium Mussaendae Pubescentis 10g, Sargassum 10g, water spinach 8g, Fructus Momordicae charantiae 8g, Auricularia 10g, Bulbus Allii Cepae 8g, Caulis et Folium Brassicae capitatae 10g, Radix Oryzae Glutinosae 10g;
The preparation method of above-mentioned capsule is as follows:
(1) weighing raw material by component proportion, the classification of all raw materials sent in parcher in batches, the parch time, parch was to parching completely according to the humid control of different component at about 5-20 minute;
(2) raw material after parch in step (1) is sent into pulverizer, be broken into smalls, be uniformly mixed so as to obtain medicamental pulverata;
(3) medicamental pulverata after step (2) mix homogeneously adds dextrin adjuvant and make soft material, in oscillating granulator, then make granule, in 80 DEG C of freeze-day with constant temperature to moisture weight lower than 5%;
(4) step (3) is produced particles filled enter capsule, pack warehouse-in after testing afterwards。
The preparation method of above-mentioned Placenta caprae seu ovis powder is as follows:
(1) after fresh Placenta caprae seu ovis sorting, foreign material are removed, put in cleanout fluid or pure water and be carried out, keep the temperature of cleanout fluid at 35-45 DEG C, first soak 35-40 minute, then pull out after cleaning up and drain surface moisture and put into temperature and be 6-8 DEG C, humidity be 78-82% fresh-keeping warehouse at least preserve more than 4 hours;
(2) Placenta caprae seu ovis in step (1) fresh-keeping warehouse is taken out, put in warm water and soak 10 minutes, then take out feeding tumbler and carry out tumbling process, during tumbling every 5-8 minute evacuation once, exhaust tumbling 5-10 minute after vacuum, then vacuum pumping, so circulation 2-4 time every time, make Placenta caprae seu ovis can reach to breathe the effect of massage in tumbling procedure, improve the activity of inner material;
While tumbling, add corn peptide 5g, curcumin 5g, Chinese liquor 20ml and soybean lecithin 50g by each Placenta Hominis, play sterilizing effect;
(3) being pulled out by the Placenta caprae seu ovis in step (2) and put into stainless cylinder of steel, adding water in rustless steel heating tank covers Placenta caprae seu ovis, is then closed by rustless steel heating tank, and heating is to 75-80 DEG C, and keeps 15-18 minute;
(4) Placenta caprae seu ovis in step (3) is put into meat grinder, pulverize with the sieve plate of Φ 8-12mm, obtain Placenta caprae seu ovis unqualified;
(5) by unqualified for the Placenta caprae seu ovis in step (4) cold preservation 3-8 hour under the environment of 4-6 DEG C, then uninterrupted microwave process is carried out to Placenta caprae seu ovis is unqualified, intermittent processing number of times is 4~10 times, and each break time is 40 seconds, and microwave treatment temperature is less than 100 DEG C;
(6) join unqualified for the Placenta caprae seu ovis after microwave treatment in step (5) in pure water, and be heated to 45 DEG C, add xylanase and stir and maintain the temperature at 45~60 DEG C of lixiviates 2~4 hours, obtain extracting solution;
Wherein Placenta caprae seu ovis is unqualified, the adding proportion of xylanase and pure water is the addition unqualified 0.6-0.7kg of Placenta caprae seu ovis, xylanase 0.03kg in every 1kg pure water;
(7) extracting solution in step (6) is heated to 100 DEG C, keep 30 minutes, after cooling, utilize the multiplex vacuum pump of circulating water type to carry out vacuum filtration, obtain the feed liquid after sucking filtration, feed liquid is carried out spray drying, collects dried object, be crushed to and namely obtain Placenta caprae seu ovis powder without bigger reunion。
The preparation method of Placenta caprae seu ovis powder of the present invention, well solves sheep placental extract in prior art and extracts existing technical problem。Production technology overcomes single Physical, chemical method or enzyme process and all removes the halfway technical barrier of precipitation, modern food new technique and traditional method are combined, microwave and enzyme extraction technology are applied in sheep placental extract production, effectively eliminate precipitation, it is ensured that the quality of product。
Capsule of the present invention is with Pericarpium Musae, rape flower, Fructus Fici, Placenta caprae seu ovis for primary raw material, through modern biotechnology, extracts medicine essence, the modern healthy product of exquisiteness。Capsule by monarch, minister, help, make prescription rigorous, clinical manifestation for subhealth state and chronic fatigue syndrome crowd, identification of etiology according to differenciation of symptoms and signs, determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs is principle, adopting the elite of Chinese crude drug, invigorating the liver and kidney is lost, the gas of benefit cardiopulmonary, it is possible to eliminate physical fatigue, health invigorating, makes people keep abundant energy in the high-speed domestic of modern city。
Capsule of the present invention is by applicant on the Clinical Basis of its many decades, in conjunction with traditional Chinese medicine theory, and the resisting fatigue meticulously developed, the product improving body energy。Rich in nutrients such as various trace elements, aminoacid, polysaccharide, nucleoside in the weary capsule of the present invention, effectively supplement the nutrients, regain one's strength, strengthen memory。Capsule of the present invention can remove the kenotoxin of tired generation, including lactic acid, oxyradical etc., and health function damage when removing tired, increase human body anti-disease ability。
Capsule of the present invention is through the detection of drug-testing center of country, and gram weary capsule is without any hormone, safe and reliable。This product has become the good merchantable brand that Athletes recovers。Strictly press GMP standard production, it is ensured that the quality of product。
Usage and consumption:
The dosage of capsule of the present invention depends on the factors such as concrete dosage form, and the age of patient, body weight, health status。Instruction: each 2, every day 3 times, the morning, noon and afternoon take, and a course for the treatment of is 1 month。
The present composition has carried out a large amount of clinical trials of substantial amounts of animal acute toxicity test, long-term toxicity test for animals and treatment disease, and the use link that this medicine puts into treatment disease provides science and objective foundation。Its test method and result of the test are as follows respectively:
(1) capsule prepared by the present invention carries out animal acute toxicity test:
Medicine: the crude drug used in the present invention is commercially available from common Chinese shop, its specification meets country's Chinese crude drug standard。
Experimental animal: white mice, body weight is at about 50g, and male and female randomly choose, market buy。
Method and result: taking white mice 30, hungry 20 hours, fill several times by every every day and feed 50g, feed one week continuously, observe 10 days, mice is movable normal, non-toxic reaction, without dead。Show that oral liquid is without acute toxicity, clinical medicine dose safety。
(2) capsule prepared by the present invention carries out long-term toxicity test for animals:
Experimental animal: rat, body weight is at 120-130g, and male and female randomly choose, market buy。
Method and result: take rat 20, it is divided into 2 groups, often group 10, wherein the 1st group as administration group, fill several times by every every day and feed 40-50g, 2nd group of diet is as a control group, once a day, fill continuously and feed 90 days, survey body weight, in latter 24 hours sacrificed by decapitation of last administration, survey blood, routine urinalysis, liver function, renal function, core, the internal organs such as kidney, the change of tissues observed form, observe the effect of dosage, observe diet, movable change, experiment proves that administration group compares without notable change with matched group, equal non-toxic reaction, it is a kind of safe drugs。
The invention has the beneficial effects as follows: the present invention is directed to subhealth state and the clinical manifestation of chronic fatigue syndrome crowd, identification of etiology according to differenciation of symptoms and signs, determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs is principle, adopt the elite of Chinese crude drug, invigorating the liver and kidney is lost, the gas of benefit cardiopulmonary, physical fatigue can be eliminated, improve sleep quality, make people keep abundant energy in the high-speed domestic of modern city。
Detailed description of the invention
For the technological means making the present invention realize, creation characteristic, reach purpose and effect and be easy to understand, below in conjunction with specific embodiment, the present invention is expanded on further。
Embodiment 1
A kind of health-caring capsule improving sleep quality, is made up of the component of following weight: Pericarpium Musae 50g, Flos Jasmini Sambac 60g, Folium toonae sinensis 30g, rape flower 60g, Fructus Fici 100g, Placenta caprae seu ovis powder 40g, Fructus Corni 20g, Os Monopteri albi 20g, ocean Rhizoma Zingiberis Recens 10g, Radix vitis romanetii leaf 10g, cane shoots leaves 10g, Herba Schizonepetae 10g, peanut sprout 10g, Ramulus et Folium Mussaendae Pubescentis 10g, Sargassum 10g, water spinach 8g, Fructus Momordicae charantiae 8g, Auricularia 10g, Bulbus Allii Cepae 8g, Caulis et Folium Brassicae capitatae 10g, Radix Oryzae Glutinosae 10g;
The preparation method of above-mentioned capsule is as follows:
(1) weighing raw material by component proportion, the classification of all raw materials sent in parcher in batches, the parch time, parch was to parching completely according to the humid control of different component at about 5-20 minute;
(2) raw material after parch in step (1) is sent into pulverizer, be broken into smalls, be uniformly mixed so as to obtain medicamental pulverata;
(3) medicamental pulverata after step (2) mix homogeneously adds dextrin adjuvant and make soft material, in oscillating granulator, then make granule, in 80 DEG C of freeze-day with constant temperature to moisture weight lower than 5%;
(4) step (3) is produced particles filled enter capsule, pack warehouse-in after testing afterwards。
The preparation method of above-mentioned Placenta caprae seu ovis powder is as follows:
(1) after fresh Placenta caprae seu ovis sorting, foreign material are removed, put in cleanout fluid or pure water and be carried out, keep the temperature of cleanout fluid at 35-45 DEG C, first soak 35-40 minute, then pull out after cleaning up and drain surface moisture and put into temperature and be 6-8 DEG C, humidity be 78-82% fresh-keeping warehouse at least preserve more than 4 hours;
(2) Placenta caprae seu ovis in step (1) fresh-keeping warehouse is taken out, put in warm water and soak 10 minutes, then take out feeding tumbler and carry out tumbling process, during tumbling every 5-8 minute evacuation once, exhaust tumbling 5-10 minute after vacuum, then vacuum pumping, so circulation 2-4 time every time, make Placenta caprae seu ovis can reach to breathe the effect of massage in tumbling procedure, improve the activity of inner material;
While tumbling, add corn peptide 5g, curcumin 5g, Chinese liquor 20ml and soybean lecithin 50g by each Placenta Hominis, play sterilizing effect;
(3) being pulled out by the Placenta caprae seu ovis in step (2) and put into stainless cylinder of steel, adding water in rustless steel heating tank covers Placenta caprae seu ovis, is then closed by rustless steel heating tank, and heating is to 75-80 DEG C, and keeps 15-18 minute;
(4) Placenta caprae seu ovis in step (3) is put into meat grinder, pulverize with the sieve plate of Φ 8-12mm, obtain Placenta caprae seu ovis unqualified;
(5) by unqualified for the Placenta caprae seu ovis in step (4) cold preservation 3-8 hour under the environment of 4-6 DEG C, then uninterrupted microwave process is carried out to Placenta caprae seu ovis is unqualified, intermittent processing number of times is 4~10 times, and each break time is 40 seconds, and microwave treatment temperature is less than 100 DEG C;
(6) join unqualified for the Placenta caprae seu ovis after microwave treatment in step (5) in pure water, and be heated to 45 DEG C, add xylanase and stir and maintain the temperature at 45~60 DEG C of lixiviates 2~4 hours, obtain extracting solution;
Wherein Placenta caprae seu ovis is unqualified, the adding proportion of xylanase and pure water is the addition unqualified 0.6-0.7kg of Placenta caprae seu ovis, xylanase 0.03kg in every 1kg pure water;
(7) extracting solution in step (6) is heated to 100 DEG C, keep 30 minutes, after cooling, utilize the multiplex vacuum pump of circulating water type to carry out vacuum filtration, obtain the feed liquid after sucking filtration, feed liquid is carried out spray drying, collects dried object, be crushed to and namely obtain Placenta caprae seu ovis powder without bigger reunion。
Model case is as follows:
Zhang, female, 36 years old, people from Jieshou City, Anhui Province。Have a sleepless night nearly 1 year, it is difficult to fall asleep, fall asleep and be prone to after the meeting wake up with a start, have a dream, sensation malaise, weak, dizzy, take the embodiment of the present invention 1 capsule continuously after 30 days, insomnia is wholly absent, and follows up a case by regular visits to 1 year without recurring。
Just so-and-so, male, 30 years old, people from Jieshou City, Anhui Province。Comparatively tired at ordinary times, pressure is big, presents interim insomnia, sometimes can only fall asleep 2-3 hour every night, and not sinking of sleeping。Rear layman starts under leading to take capsule of the present invention, takes medicine of the present invention continuously after 60 days, and the length of one's sleep was up to 6 hours every night, follows up a case by regular visits to 1 year without recurrence。
The ultimate principle of the present invention and principal character and advantages of the present invention have more than been shown and described。Skilled person will appreciate that of the industry; the present invention is not restricted to the described embodiments; described in above-described embodiment and description is that principles of the invention is described; without departing from the spirit and scope of the present invention; the present invention also has various changes and modifications, and these changes and improvements both fall within the claimed scope of the invention。Claimed scope is defined by appending claims and equivalent thereof。

Claims (3)

1. the health-caring capsule improving sleep quality, it is characterized in that, be made up of the component of following weight: Pericarpium Musae 50g, Flos Jasmini Sambac 60g, Folium toonae sinensis 30g, rape flower 60g, Fructus Fici 100g, Placenta caprae seu ovis powder 40g, Fructus Corni 20g, Os Monopteri albi 20g, ocean Rhizoma Zingiberis Recens 10g, Radix vitis romanetii leaf 10g, cane shoots leaves 10g, Herba Schizonepetae 10g, peanut sprout 10g, Ramulus et Folium Mussaendae Pubescentis 10g, Sargassum 10g, water spinach 8g, Fructus Momordicae charantiae 8g, Auricularia 10g, Bulbus Allii Cepae 8g, Caulis et Folium Brassicae capitatae 10g, Radix Oryzae Glutinosae 10g。
2. the method preparing capsule described in claim 1, it is characterised in that step is as follows:
(1) weighing raw material by component proportion, the classification of all raw materials sent in parcher in batches, the parch time, parch was to parching completely according to the humid control of different component at 5-20 minute;
(2) raw material after parch in step (1) is sent into pulverizer, be broken into smalls, be uniformly mixed so as to obtain medicamental pulverata;
(3) medicamental pulverata after step (2) mix homogeneously adds dextrin adjuvant and make soft material, in oscillating granulator, then make granule, in 80 DEG C of freeze-day with constant temperature to moisture weight lower than 5%;
(4) step (3) is produced particles filled enter capsule, pack warehouse-in after testing afterwards。
3. a kind of health-caring capsule improving sleep quality according to claim 1, it is characterised in that the preparation method of above-mentioned Placenta caprae seu ovis powder is as follows:
(1) after fresh Placenta caprae seu ovis sorting, foreign material are removed, put in cleanout fluid or pure water and be carried out, keep the temperature of cleanout fluid at 35-45 DEG C, first soak 35-40 minute, then pull out after cleaning up and drain surface moisture and put into temperature and be 6-8 DEG C, humidity be 78-82% fresh-keeping warehouse at least preserve more than 4 hours;
(2) Placenta caprae seu ovis in step (1) fresh-keeping warehouse is taken out, put in warm water and soak 10 minutes, then take out feeding tumbler and carry out tumbling process, during tumbling every 5-8 minute evacuation once, exhaust tumbling 5-10 minute after vacuum, then vacuum pumping, so circulation 2-4 time every time;
Corn peptide 5g, curcumin 5g, Chinese liquor 20ml and soybean lecithin 50g is added by each Placenta Hominis while tumbling;
(3) being pulled out by the Placenta caprae seu ovis in step (2) and put into stainless cylinder of steel, adding water in rustless steel heating tank covers Placenta caprae seu ovis, is then closed by rustless steel heating tank, and heating is to 75-80 DEG C, and keeps 15-18 minute;
(4) Placenta caprae seu ovis in step (3) is put into meat grinder, pulverize with the sieve plate of Φ 8-12mm, obtain Placenta caprae seu ovis unqualified;
(5) by unqualified for the Placenta caprae seu ovis in step (4) cold preservation 3-8 hour under the environment of 4-6 DEG C, then uninterrupted microwave process is carried out to Placenta caprae seu ovis is unqualified, intermittent processing number of times is 4~10 times, and each break time is 40 seconds, and microwave treatment temperature is less than 100 DEG C;
(6) join unqualified for the Placenta caprae seu ovis after microwave treatment in step (5) in pure water, and be heated to 45 DEG C, add xylanase and stir and maintain the temperature at 45~60 DEG C of lixiviates 2~4 hours, obtain extracting solution;
Wherein Placenta caprae seu ovis is unqualified, the adding proportion of xylanase and pure water is the addition unqualified 0.6-0.7kg of Placenta caprae seu ovis, xylanase 0.03kg in every 1kg pure water;
(7) extracting solution in step (6) is heated to 100 DEG C, keep 30 minutes, after cooling, utilize the multiplex vacuum pump of circulating water type to carry out vacuum filtration, obtain the feed liquid after sucking filtration, feed liquid is carried out spray drying, collects dried object, be crushed to and namely obtain Placenta caprae seu ovis powder without bigger reunion。
CN201610119676.1A 2016-03-02 2016-03-02 Healthcare capsule for improving sleeping quality Withdrawn CN105688146A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108452107A (en) * 2017-02-10 2018-08-28 百岳特生物科技(上海)有限公司 Application of banana peel extract in regulation and control of TPH1, DDC and/or AANAT gene expression
CN113678915A (en) * 2021-07-30 2021-11-23 珠海无糖无恙健康管理有限公司 Food helpful for sleeping and preparation device thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104758686A (en) * 2015-04-02 2015-07-08 王永帮 Traditional Chinese medicine preparation for treating poor sleep quality
CN105343128A (en) * 2015-11-19 2016-02-24 界首市菁华科技信息咨询服务有限公司 Processing method of sheep placenta instant powder

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104758686A (en) * 2015-04-02 2015-07-08 王永帮 Traditional Chinese medicine preparation for treating poor sleep quality
CN105343128A (en) * 2015-11-19 2016-02-24 界首市菁华科技信息咨询服务有限公司 Processing method of sheep placenta instant powder

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108452107A (en) * 2017-02-10 2018-08-28 百岳特生物科技(上海)有限公司 Application of banana peel extract in regulation and control of TPH1, DDC and/or AANAT gene expression
CN113678915A (en) * 2021-07-30 2021-11-23 珠海无糖无恙健康管理有限公司 Food helpful for sleeping and preparation device thereof

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Application publication date: 20160622