CN103719491A

CN103719491A - Rhizoma polygonati health-care tea for invigorating spleen and moistening lung and preparation method thereof

Info

Publication number: CN103719491A
Application number: CN201310749533.5A
Authority: CN
Inventors: 不公告发明人
Original assignee: Qingdao Hengbo Instrument Co Ltd
Current assignee: Jiangsu love Biotechnology Co., Ltd.
Priority date: 2013-12-31
Filing date: 2013-12-31
Publication date: 2014-04-16
Anticipated expiration: 2033-12-31
Also published as: CN103719491B

Abstract

The invention provides rhizoma polygonati health-care tea for invigorating the spleen and moistening the lung. The rhizoma polygonati health-care tea for invigorating the spleen and moistening the lung comprises the following raw materials in parts by weight: 10-50 parts of rhizoma polygonati, 10-20 parts of radix ophiopogonis, 10-20 parts of dried radix rehmanniae, 10-20 parts of poria cocos, 10-20 parts of codonopsis pilosula, 10-20 parts of knotweed, 10-20 parts of reed rhizome, 10-20 parts of white mulberry root-bark, 10-20 parts of coix seeds, 10-20 parts of white atractylodes rhizome, 10-20 parts of rhizoma fagopyri dibotryis, 10-20 parts of platycodon grandiflorum, 10-20 parts of tangerine, 10-20 parts of hawthorn, 10-20 parts of melon kernel, 10-20 parts of adenophora stricta, 10-20 parts of Chinese magnoliavine fruit and 10-20 parts of jujube. The rhizoma polygonati can be effectively used for invigorating the spleen, moistening the lung and reducing fat, promoting blood circulation to remove blood stasis, and reducing blood fat, blood pressure, cholesterol, and blood glucose, mainly used for treating yin-deficiency and overstrain cough, lung dryness and cough, insufficiency of the spleen and hypodynamia, and reduced appetite and dry mouth; the traditional Chinese medicinal materials for promoting blood circulation to remove blood stasis, invigorating spleen, inducing diuresis and nourishing yin are added; most of the medicinal materials are light in taste, free of inedible traditional Chinese medicine taste, and easy to accept by people, and can be taken for a long period of time, and the effects of invigorating the spleen and moistening the lung can be better achieved.

Description

A kind of sealwort invigorating the spleen moistening lung health protection tea and preparation method thereof

Technical field

The present invention relates to contain the invigorating the spleen moistening lung health products that derive from plant composition, particularly a kind of sealwort invigorating the spleen moistening lung health protection tea and preparation method thereof.

Background technology

Modern economy high speed development, unavoidably brings a lot of negatively influencings, environmental pollution, and air quality causes anxiety and perplexs really healthy killer.We is all breathing every day, and decline that can air quality, causes various inflammation in respiratory system, affects too the whole upper respiratory tract, even affects the lung in body.Lung is the ventilation forest of guarding health, be unique whole day 24 hours all with the internal organ of external environment condition " directly interactive ".Every day, 10,000 liters of gases of its inspiration exhalation, are equivalent to 250 standard medical oxygen tanks.Various dust granules, chemical substance, pathogen, also often taking " windward driving " of breathing and invading lung.Due to the harm that overall situation is polluted, it is more and more fragile that modern's lung is just becoming, and is worth people to pay close attention to.Lung capacity is the common counter of test PFT.Normal adult lung capacity is about 2400-3400 milliliter.But many investigation show, lung capacity continuous decrease, has become the popular tendency of all age group.Compared with 1985,7 years old to 18 years old Middle school students and pupils's lung capacity of China in 2010 declined 11.4%, and university student has declined nearly 10%.The thing followed is that respiratory disease is increasing.Now, the common incidence of disease that comprises the diseases such as chronic obstructive pulmonary disease, bronchial astehma, lung cancer, cardiopulmonary blood vessel is all in continuous rising.

In the < < medical science source and course opinion > > that Qing Dynasty's well-known doctor's Xu Dachun is write, claim that lung is " tender dirty ", i.e. tender and lovely internal organs, fever and chills all institute are unsuitable.Lung is clear empty and occupy high-orderly, has the title of " canopy " of the vital organs of the human body.In all organs, lung is maximum with the chance of extraneous " direct dialogue ", but there is no Additional Protection, can only lean on " oneself purifies ", by modes such as cough, expectorations, discharges nuisance.But severe living environment, has allowed lung " can't bear the heavy load ".Investigation demonstration, in China's patients with COPD, 39% people does not have smoking history.Analyze its pathogenic factor, " arch-criminal " is exactly air pollution.Expert points out, lung is that human body carries " exhaust collection device ", and the various pernicious gases such as tail gas, dust, are all the factors that affects lung health.Take PM2.5 as example, a large amount of science data prove that itself and lung cancer, asthma are closely related.Well-known doctor, member of Chinese Academy of Engineering Zhong Nanshan is just afraid of most gray haze sky.In his view, may to mean that division of respiratory disease Number of Outpatients can increase many for such weather." a large amount of pollutants are inhaled into lung, and a lot of people's lungs have been lost self-detergent power.”

In addition smoking,, kitchen fume are also " killers " who causes tuberculosis.Also have the various chemicals of inevitable contact in life, as the various poisonous chemical composition of drifting in new decorating house, market, office space, the chemical substance that all causes lung to suck is more and more.To this, an old doctor also has deep feeling: " when graduated from university just, see big city patient's lung or pink, soft.Gradually, find for a long time townie people, lung surface can be attached with stain to some extent.If lung does not have blackening, the stain adhering to is also few, is that rural area is come most likely." expert emphasizes, lung health is very large to heart stimulation, if the illness such as chronic bronchitis, bronchial astehma, pulmonary tuberculosis constantly increase the weight of, can affect the oxygen exchange of blood at alveolar-capillary membrane, brings out pulmonary hypertension and pulmonary heart disease." PFT arrived peak in the time of more than 20 year old, after this declined year by year." medical science points out, people should start since young, initiatively protect lung.If panted during stair climbing, first to consider whether to have heart hypofunction; The also asthma if walk in level land may be just that decline in pulmonary function causes.Expert reminds, if lung pathology occurs lower than 50%, health is not felt; If exceed 50%, there is symptom, then gone to see the doctor, just too late.Within 45 years old, above people will, as Monitoring of blood pressure, look into PFT one time to hospital at least every year.Long-term smoking, RRTI, Long Term Contact indoor pollution, occupational dust contactee, more should check as early as possible.

Sealwort is used as medicine with rhizome.There is boosting qi and nourishing yin, invigorating the spleen, moistening lung, kidney benefiting functions.Be used for the treatment of weakness of the spleen and the stomach, fatigue and asthenia, dry food is few, deficiency syndrome of the lung cough caused by dryness, asthenia of essence and blood, the interior heat disease such as quench one's thirst.Very effective in cure for diabetes.Sealwort main product in Hebei, the provinces and regions such as Inner Mongol, Shaanxi Province.David's-harp main product in Guizhou, the province such as Hunan, Yunnan, Anhui, Zhejiang.Yunnan sealwort main product in Guizhou, the provinces and regions such as Guangxi, Yunnan.Property sugariness flat, return spleen; Lung; Kidney channel, is boosting qi and nourishing yin, invigorating the spleen, moistening lung, the good medicine of kidney-nourishing.Curing mainly deficiency of Yin labor coughs; Xeropulmonary cough; Insufficiency of the spleen weak; The few dry of food; Quench one's thirst; Deficiency of the kidney soreness and weakness of waist and knees; Impotence and seminal emission; Tinnitus order is dark; Poliosis; The empty win of body is thin; Wind favus disease.

Sealwort has hypotensive, hypoglycemic, reducing blood lipid, and atherosclerosis, delays senility and effect such as antibacterial grade, and Siberian solomonseal rhizome polysaccharide has Immunestimulatory effect.For the lung-dryness syndrome due to yin deficiency, the few phlegm of dry cough, and the labor of the lung-kidney deficiency chronic cough etc. of coughing.For weakness of the spleen and the stomach.Both tonifying spleen-yin, beneficial temper again, for deficiency of kidney essence, obtain dizzy, soreness and weakness of waist and knees, poliosis and quenching one's thirst etc.The good medicine of nourishing of good moistening lung help.But three points of poison of medicine, also produce resisting psychology while allowing people's long-term taking.How the efficacy exertion of sealwort not being injured again to human body to maximum, is our problem in the urgent need to address.

In all organs, lung is maximum with the chance of extraneous " direct dialogue ", but there is no Additional Protection, can only lean on " oneself purifies ", by modes such as cough, expectorations, discharges nuisance.But severe living environment, has allowed lung " can't bear the heavy load ".This, the effective invigorating the spleen moistening lung of search of health method has very real significance, and the active material of invigorating the spleen moistening lung is safely and effectively that people expect the key of dealing with problems always.Chinese medicine sealwort invigorating the spleen moistening lung, have advantages of nontoxic, can be absorbed completely by organism, be the main direction that we study.Now market is in the urgent need to developing a kind of have invigorating the spleen moistening lung health products nontoxic, the advantage that can be absorbed completely by organism.

Summary of the invention

Technical problem to be solved by this invention is, it is more and more fragile that modern's lung is just becoming, environmental pollution, and smoking causes the incidence of disease of the diseases such as chronic obstructive pulmonary disease, bronchial astehma, lung cancer, cardiopulmonary blood vessel all in continuous rising.In all organs, lung is maximum with the chance of extraneous " direct dialogue ", but there is no Additional Protection, can only lean on " oneself purifies ", by modes such as cough, expectorations, discharges nuisance.But severe living environment, has allowed lung " can't bear the heavy load ".The effective invigorating the spleen moistening lung of search of health method has very real significance, and the active material of invigorating the spleen moistening lung is safely and effectively that people expect the key of dealing with problems always.Sealwort sugariness is flat, returns spleen; Lung; Kidney channel, is boosting qi and nourishing yin, invigorating the spleen, moistening lung, the good medicine of kidney-nourishing.Curing mainly deficiency of Yin labor coughs; Xeropulmonary cough; Insufficiency of the spleen weak; The few dry of food; Quench one's thirst; Deficiency of the kidney soreness and weakness of waist and knees; Impotence and seminal emission; Tinnitus order is dark; Poliosis; The empty win of body is thin; Wind favus disease.These compositions have the merit of invigorating the spleen moistening lung, add some mouthfeels light, do not affect the Chinese medicine of sealwort taste, make people be easy to accept, and can reach preferably the effect of invigorating the spleen moistening lung.

For solving above-mentioned technical barrier, the invention provides a kind of sealwort invigorating the spleen moistening lung health protection tea, in described sealwort invigorating the spleen moistening lung health protection tea, the parts by weight of various raw materials are: 10～50 parts of sealworts, 10～20 parts of the tubers of dwarf lilyturf, 10～20 parts, the dried rhizome of rehmannia, 10～20 parts, Poria cocos, 10～20 parts of Radix Codonopsis, 10～20 parts of asters, 10～20 parts of reed rhizomes, 10～20 parts of the root barks of white mulberry, 10～20 parts of heart of a lotus seed benevolence, 10～20 parts of the bighead atractylodes rhizomes, 10～20 parts of cymose buckwheat rhizomes, 10～20 parts of balloonflower roots, 10～20 parts of Exocarpium Citri Rubrums, 10～20 parts of hawthorn, 10～20 parts of Semen Benincasaes, 10～20 parts of the root of straight ladybell, 10～20 parts, the fruit of Chinese magnoliavine, 10～20 parts, date.

Described sealwort invigorating the spleen moistening lung health protection tea, described in it, in sealwort invigorating the spleen moistening lung health protection tea, the parts by weight of various raw materials can be: 20～40 parts of sealworts, 10～15 parts of the tubers of dwarf lilyturf, 10～15 parts, the dried rhizome of rehmannia, 10～15 parts, Poria cocos, 10～15 parts of Radix Codonopsis, 10～15 parts of asters, 10～15 parts of reed rhizomes, 10～15 parts of the root barks of white mulberry, 10～15 parts of heart of a lotus seed benevolence, 10～20 parts of the bighead atractylodes rhizomes, 10～20 parts of cymose buckwheat rhizomes, 10～20 parts of balloonflower roots, 10～20 parts of Exocarpium Citri Rubrums, 10～20 parts of hawthorn, 10～20 parts of Semen Benincasaes, 10～20 parts of the root of straight ladybell, 10～20 parts, the fruit of Chinese magnoliavine, 10～20 parts, date.

Described sealwort invigorating the spleen moistening lung health protection tea, described in it, in sealwort invigorating the spleen moistening lung health protection tea, the parts by weight of various raw materials can also be: 10～30 parts of sealworts, 10～20 parts of the tubers of dwarf lilyturf, 10～20 parts, the dried rhizome of rehmannia, 10～20 parts, Poria cocos, 10～20 parts of Radix Codonopsis, 10～20 parts of asters, 10～20 parts of reed rhizomes, 10～20 parts of the root barks of white mulberry, 10～20 parts of heart of a lotus seed benevolence, 10～15 parts of the bighead atractylodes rhizomes, 10～15 parts of cymose buckwheat rhizomes, 10～15 parts of balloonflower roots, 10～15 parts of Exocarpium Citri Rubrums, 10～15 parts of hawthorn, 10～15 parts of Semen Benincasaes, the root of straight ladybell 10～, 15 parts, 10～15 parts, the fruit of Chinese magnoliavine, 10～15 parts, date.

For solving the problems of the technologies described above, the present invention also provides the preparation method of a kind of sealwort invigorating the spleen moistening lung health protection tea, and its preparation process comprises following aspect:

A. the preparation of sealwort;

B. by described other raw material pulverizing, immersion, heating, refluxing extraction 2 times;

C. the liquid again surplus stock being extracted is condensed into granule, pulvis or paste;

D. concentrated granule, pulvis or paste are mixed with the sealwort preparing, be prepared into health care medicinal tea.

In described step a, the sealwort of results can be cleaned, the airing time, at 7-12 hour, parches; Be cut into thin slice, put a pot interior water proof and steam 30-60 minute at 80-100 ℃, then dry; After drying, repeat again to steam once, dry; Then put into large iron pan and stir-fry, first downwards backward upper, firmly want evenly, when sealwort color starts blackout, start the moulding in 30-45 minute that stir-fries of little fire; When color becomes pitchy, after taking out, naturally dry.

In described step b, surplus stock can be cleaned to impurity elimination, dry, be ground into particle, soak 1 hour; Soaked raw material is put to boiling secondary in multi-function extractor; Add up for the first time the water of 10 times of amounts of medicinal material, decoct 1.5～2 hours, get decocting liquid, filter; Add for the second time the water of 7 times of amounts of total amount, decoct 1～1.2 hour, get twice decocting liquid and mix, filter.

In described step c, the filtrate of filtration can be inserted in economic benefits and social benefits vacuum concentrator to the concentrate that while being concentrated into 90 ℃, relative density is 1.05, set to 0～5 ℃ of deepfreezes 24 hours; Refrigeration liquid is added to 0.3% filter aid diatomite, filter, filtrate is inserted in economic benefits and social benefits vacuum concentrator again, is concentrated into every 1ml containing 1g crude drug amount, then adds dextrin and puts into granulator and granulate.

In described steps d, the particle that sealwort good frying can be prepared with surplus stock mixes, and ultraviolet disinfection, packs and get final product.

For solving the problems of the technologies described above, the present invention provides the preparation method of a kind of sealwort invigorating the spleen moistening lung health protection tea again, when other raw materials of described sealwort invigorating the spleen moistening lung Antilipemic health tea are made pulvis, step is: other raw materials are put into 10 times of amount ethanol, heating and refluxing extraction 2 times, each 1～2 hour, No. 2 extracts are merged standing; The dregs of a decoction of the component raw medicinal material of more above-mentioned alcohol extract being crossed add 10 times of water gaging heating and refluxing extraction 2 times, each 1～2 hour, No. 2 extracts are merged standing; Above-mentioned two kinds of extracts are merged, and reclaiming after ethanol decompression, to put into inspissator concentrated, then puts into drying baker and be dried into powder, after ultraviolet radiation for sterilizing and disinfecting, merges packing with the good sealwort of frying.

In above-mentioned concentration step, two kinds of extracts are merged, reclaiming after ethanol decompression, to put into inspissator concentrated, the concentrate that while being concentrated into 90 ℃, relative density is 1.05, set to 0～5 ℃ of deepfreezes 24 hours; Refrigeration liquid is added to 0.3% filter aid diatomite, filter, filtrate is inserted in economic benefits and social benefits vacuum concentrator again, is concentrated into every 1ml containing 1g crude drug amount.

The technique effect that the present invention is useful is, that the present invention has advantages of is nontoxic, can be absorbed completely by organism.Not only effectively invigorating the spleen moistening lung lipopenicillinase of sealwort, promoting blood circulation and removing blood stasis, invigorating the spleen moistening lung, reducing blood lipid, hypotensive, reduce cholesterol, reduce blood sugar, the composition of blood is purified, but also can improve microcirculation, reduce the fragility of capillary, reduce its permeability, cure mainly deficiency of Yin labor and cough; Xeropulmonary cough; Insufficiency of the spleen weak; The few dry of food; Add that some are promoting blood circulation and removing blood stasis, the Chinese medicine of invigorating spleen to remove dampness yin-nourishing, the most mouthfeel of these medicinal materials is light, do not affect the taste of King solomonseal rhizome tea, there is no the unpleasant taste of traditional Chinese medicine that is difficult to hypopharynx, make people be easy to accept, can long-term taking, more can reach preferably the effect of invigorating the spleen moistening lung.

The specific embodiment

Sealwort is conventional tonic Chinese herbal medicine, in China's medication history of existing more than 2000 year, is Liliaceae Polygonatum herbaceos perennial, medicinal its rhizome.Sealwort is flat, taste is sweet, returns spleen, lung, kidney channel, has the effect of tonifying spleen moistening lung, supplementing qi and nourishing yin, is used for the treatment of the diseases such as body void is weak, palpitation, dryness of the lung dry cough, ringworm of the body.

In recent years, people deepen continuously to the research of sealwort and Polygonatum plant thereof, and from sealwort plant, having separated the chemical composition obtaining has alkaloid, flavones, quinones, lignanoid, polysaccharide, steroid saponin and trace element etc.

1, regulate blood sugar effect

Siberian solomonseal rhizome polysaccharide has no significant effect normal mouse blood sugar level, but can significantly reduce the blood glucose value of the hyperglycaemia mouse that adrenaline brings out, reduces the content 8A of CAMP cAMP in adrenaline model mice liver simultaneously:.Normal mouse abdominal cavity gives sealwort methanolic extract 800mg/kg, after 4h, can make blood sugar drop to (144 ± 13) mg/dL from (220 ± 7) mg/dL, the blood sugar that streptozotocin under similarity condition (STZ) brings out hyperglycaemia mouse (insulin-dependent model) drops to (396 ± 15) mg/dL from (589 ± 34) mg/dL, but it does not change serum insulin levels in hypoglycemic activity.This extract suppresses adrenaline in addition brings out the effect of hyperglycaemia mouse blood sugar.Someone separates and obtains 2 active components from its active site, through being accredited as spirostanol glycoside.

2, regulate immunization

By high, medium and low dosage Siberian solomonseal rhizome polysaccharide, the impact test of Phagocytosis By The Peritoneal Macrophages In Mice, mouse Hemolysin formation and delayed allergy (DTH) is found, the immunoregulation effect of Siberian solomonseal rhizome polysaccharide clearly, not only can strengthen mouse humoral immune function, also can strengthen the function of mouse cell immunity.Immunocompetence is screened and is shown, sealwort can improve the hemopoietic function of bone marrow that is subject to endoxan processing mouse, makes its leucocyte and erythrocyte number increase, and Micronucleus declines, and the phagocytic function of Turnover of Mouse Peritoneal Macrophages improves.With sealwort decocting liquid 0.5g/d, feed and raise 10d continuously to every mouse, result normal mouse plasma cAMP, cyclic guanosine monophosphate (cGMP) content reduce, especially with cGMP, reduce significantly, cAMP/cGMP ratio slightly raises (comparing without significant difference with control group); Normal mouse spleen organizes the content of cGMP but obviously to raise.

3, improve learning and memory effect

To hyoscine, cause the continuous gavage of learning memory disorder model mice with saponins of rhizoma polygonati (PTS), result shows that PTS can obviously improve the learning and memory function of model mice under 400mg/kg dosage.With Siberian solomonseal rhizome polysaccharide 200, 100, it (is hydergene as positive control that 50mg/kg3 dosage is given the continuous gavage 15d. of old rats respectively, negative control is equivalent distilled water), within after administration the 15th day and the 30th day, with y type labyrinth, carry out learning test, result shows that Siberian solomonseal rhizome polysaccharide can significantly improve old rats learning and memory and memory represents ability, reduce errors number (compared with positive control, all extremely significantly (P<0.01) of Siberian solomonseal rhizome polysaccharide 200mg/kg and 100mg/kg dosage group difference, 50mg/kg dosage group significant difference (P<0.05).Give vascular dementia rat models with every 100g body weight 0.5ml gavage 1 week, then with 10% sealwort oral liquid, continue medication 1.5 months and 2.5 months (clothes drink naturally), result shows that sealwort oral liquid has the effect of reinventing synaptic structure and function, improving vascular dementia SD female rats ability of learning and memory.

4, bacteriostasis

Sealwort decocting liquid (1: 30) has inhibitory action to typhoid bacillus, staphylococcus aureus, tubercle bacillus, acid-fast bacillus etc., after the experimental tuberculosis cavy of 1g/kg dosage treatment every day 60d, find that its main organs pathology is lighter, only there is minority tubercle in lung.Sealwort all has inhibitory action to multiple pathogenic microorganisms, and sealwort water extraction liquid has stronger inhibitory action to typhoid bacillus, staphylococcus aureus in vitro, and multiple pathomycete is also had to inhibitory action.

5, anti-inflammatory, antivirus action

Peng Cheng etc. give the antiinflammatory action of Siberian solomonseal rhizome polysaccharide eyedrops investigation Siberian solomonseal rhizome polysaccharide by rabbit eyes conjunctiva, Corneal inflammation model, result Siberian solomonseal rhizome polysaccharide eyedrops can be eliminated the local symptoms such as rabbit model conjunctival congestion, oedema, secretion increase, the opacity of the cornea, ciliary congestion, can obviously suppress mice auricle swelling, the swelling of rat toes, can also reduce the granulomatous quality of rat, reduce in granuloma and ooze out, prompting Siberian solomonseal rhizome polysaccharide has good antiinflammatory action.With 0.2% Siberian solomonseal rhizome polysaccharide eye drops, 2mg/ml Siberian solomonseal rhizome polysaccharide parenteral solution and 3 kinds of preparation for treating rabbit experiment herpes simplex keratitis of 0.5% Siberian solomonseal rhizome polysaccharide oral liquid, result Siberian solomonseal rhizome polysaccharide preparation group is than more obviously (P<0.05) of the curative effect of chloromycetin group, and Siberian solomonseal rhizome polysaccharide eye drops eye drip coordinates Siberian solomonseal rhizome polysaccharide parenteral solution subconjunctival injection group and Siberian solomonseal rhizome polysaccharide eye drops eye drip to coordinate the curative effect of Siberian solomonseal rhizome polysaccharide oral liquid group to be all better than acyclovir group (P<0.05).

6, antifatigue effect

Mouse peritoneal injection sealwort solution 12g/kg, can obviously improve mouse hypoxia-bearing capability; With sealwort water decoction 2.55g/kg gavage mouse, can significant prolongation mouse swimming time (P<0.05).

7, adjust fat effect

With basic, normal, high dosage Siberian solomonseal rhizome polysaccharide, give 30 of the new zealand purebred rabbits (male and female half and half) after High cholesterol diet is fed, result animal used as test sustainer general form and om observation show, Siberian solomonseal rhizome polysaccharide high dose group aortic tunica intima foam cells forms obvious minimizing (P<0.05), shows that doses Siberian solomonseal rhizome polysaccharide has the effect that reduces hyperlipidemia animal used as test blood fat and the effect that suppresses the formation of endarterium foam cells.In addition, Siberian solomonseal rhizome polysaccharide obviously reduces in Ad model mice liver, the content of cAMP, thereby infer that its hypoglycemic mechanism is to have reduced in liver cell, the content of cAMP, has hindered phosphorylase and has activated and glycogen synthetase inactivation, thereby causes the synthetic acceleration of glycogen, decomposition of glycogen to slow down.Siberian solomonseal rhizome polysaccharide reduces, and the mechanism of cAMP may affect the expression of adrenocepter or cause that the conformational change of acceptor is relevant with it, and this respect also needs further to studies confirm that.

8, delaying senility function

With sealwort oral liquid 0.2, the continuous gavage mouse of 0.4ml/d 4 weeks (making respectively the positive, negative control with Oral Liquid Radix Panacis Quinquefolii and water respectively), after swimming 90min, put to death, this oral liquid of result can significantly reduce the heart, liver lipid peroxide LPO) generation P<0.01, increase glutathione peroxidase activity and blood superoxide dismutase SOD vigor, and be dose dependent; Compared with positive controls, sealwort oral liquid suppresses the heart, liver LPO generative capacity obviously increases, and is also dose dependent, shows that it has anti-ageing anti-old effect.Someone has studied the Antioxidation in vitro of Siberian solomonseal rhizome polysaccharide, result shows that it can suppress generation spontaneous and lipid peroxidation product MDA (MDA) induction in vitro, oxygen radical is had to direct scavenging action, show Siberian solomonseal rhizome polysaccharide anti-oxidant and anti-aging aspect there is certain effect.

Along with progressively going deep into sealwort pharmacology, pharmaceutical chemistry and clinical research, people find and confirm in sealwort plant that steroid saponin and analogous components thereof have some good pharmacologically actives gradually, and existing patent application, as patents such as " steroid saponin in Chinese medicine sealwort and medical usage thereof and the preparation methods " of Lee's milling.Simultaneously, active site based on Polygonatum plant and the research of active ingredient, people are also carrying out New Drug Research, sealwort and glycocalix thereof have been made some Chinese patent drugs evident in efficacy, health products, new antiviral drug, oral liquid, as Siberian solomonseal rhizome polysaccharide eye drops, antiviral Siberian solomonseal rhizome polysaccharide sulfuric ester, Wonderful creme and the spray of prevention and treatment genital herpes, the ancient crane pine health liquor of tool deferring senility, Siberian solomonseal rhizome polysaccharide oral liquid, sealwort radix paeoniae rubrathe parenteral solution, sealwort medicinal extract etc.At present; the ground such as Guizhou, Shaanxi has started to carry out the artificial cultivation test of sealwort; and embark Good Agricultural Practice base and carry out the correlative study of planting rhizoma polygonati standardization rules; this,, by for standardization production, effective control of Quality of Chinese Traditional Proprietary Medicine and the protection of natural resources of relevant Chinese patent drug provide safeguard, also provides reliable basis by the research for sealwort, exploitation, utilization.But current research is still not deep enough: as the difference of the medicinal material of different plant origins on composition and content and the pharmacologically active of composition how; What the scientific meaning of its process of preparing and quality control index be; Steroid saponin in sealwort, polysaccharide, flavones, alkaloid etc. which be the main active ingredient of the traditional Chinese medical science tradition property of medicine, and which can cause the bad reactions such as stimulation; What steroid saponin constituents structure-activity relationship and mechanism of action hypoglycemic, antitumor, that improve learning and memory be, etc.These problems are all worth further investigated, to lay the foundation for the further exploitation of Polygonatum plant.

All on the books to sealwort in < < Chinese medicine voluminous dictionary > > and pertinent literature: can calm the nerves, the swollen wind pain of lively atmosphere blood, the wide intestines of sending down abnormally ascending, heat-clearing, long-pendingization of dispelling are stagnant, gut purge, ease constipation, invigorating the spleen moistening lung, cough-relieving, relieving asthma, the effect such as anti-inflammatory, antiallergy, cardiac stimulant, invigorating the spleen moistening lung, beauty treatment.Sealwort--seven major nutrient complete set, is not medicine, is not health products, is to work as the food that meal is eaten, and but has remarkable healthy nutritive value and outstanding dietotherapy effect.Sealwort is rich in grease, and property is slided profit more.Modern pharmacological research shows, these compositions have the merit of invigorating the spleen moistening lung.

Radix Codonopsis is the conventional traditional tonic of China, and the Radix Codonopsis that produce ancient times take area, Shangdang, Shanxi, as top grade, has tonifying middle-Jiao and Qi, the effect of invigorating the spleen benefit lung.Modern study, Radix Codonopsis, containing various saccharides, phenols, sterol, volatile oil, scutellarein glucosid, saponin and Alkaloid, has immunity, hemangiectasis, the step-down of enhancing, improves microcirculation, strengthens the effects such as hematopoiesis function.In addition leucocyte chemotherapy radiotherapy being caused declines castering action.Radix Codonopsis has tonifying middle-Jiao and Qi, the effect of invigorating the spleen benefit lung.For a little less than the spleen deficiency syndrome of the lung, the palpitaition of breathing hard, anorexia and loose stool, void is breathed with cough and is coughed, and interior heat is quenched one's thirst etc.< < new compilation of materia medica > > records: " tonifying middle-Jiao and Qi and taste, relieving thirst and restlessness.Middle gas is faint, in order to adjust, mends, very smooth and proper.”

Poria cocos taste is sweet, light, property is flat, be used as medicine there is clearing damp and promoting diuresis, the function of beneficial spleen and stomach, antitoxic heart-soothing and sedative.Modern medicine study: Poria cocos energy enhanced machine body immunity function, pachymaran has significantly antitumor and protect the liver dirty effect.Poria cocos slightly sweet flavor is flat, enters the heart, lung, the spleen channel.There is eliminating dampness and diuresis, strengthening the spleen and stomach, the effect of antitoxic heart-soothing and sedative.Can control difficult urination, oedema turgor, phlegm and retained fluid is coughed contrary, vomits contrary, and vomiting during early pregnancy, has loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful disease such as grade.The Li Shui of Poria cocos, reaches by strong fortune spleen PFT, different from the Chinese medicine of other direct Li Shui.For splenasthenic diarrhea, the lower Poria cocos of band can invigorating the spleen, again can excreting dampness, and due to insufficiency of the spleen dysfunction of the spleen in transportation and transformation, to have loose bowels, be with down, application Poria cocos has the effect of giving consideration to both the incidental and fundamental, the compatibilities such as normal and Radix Codonopsis, the bighead atractylodes rhizome, Chinese yam.Can be used as tonifying lung spleen, control the adjuvant of the deficiency of vital energy.

Heart of a lotus seed benevolence is conventional Chinese medicine. be again the food of generally, often eating, property slightly sweet flavor is slightly cold, and has that inducing diuresis for removing edema, invigorating the spleen are dried, relaxing muscles and tendons is except effects such as numbness, clearing away heat and eliminating pus, is conventional damp-clearing drug.Heart of a lotus seed benevolence is again a kind of beauty food, and normal food can keep human body skin gloss exquisiteness, eliminates acne, spot sparrow, senile plaque expelling, cyasma, butterfly macules, to furfur, acne, chap, pachylosis etc. has good efficacy.The kind Renhe root of the seed of Job's tears can be used as medicine and cure the disease again.Li Shizhen (1518-1593 A.D.) is recorded in < < Compendium of Materia Medica > >: " invigorating spleen and reinforcing stomach, tonifying lung heat-clearing, removes wind prevailing over dampness to seed of Job's tears energy.The food of cooking a meal, controls cold air.Decoct drink, diuresis heat is drenched." in recent years, a large amount of scientific research and clinical practices prove, the seed of Job's tears or a kind of cancer therapy drug, and Preliminary Identification, it can reach more than 35% the inhibiting rate of cancer.

Bighead atractylodes rhizome bitter, sweet, temperature.Return spleen, stomach warp.Cure mainly strengthening the spleen and replenishing qi, eliminating dampness Li Shui, hidroschesis, antiabortive.Few for insufficiency of the spleen food, abdominal distension is had loose bowels, and phlegm and retained fluid is dizzy throbs with fear, oedema, spontaneous perspiration, fetal irritability.The bighead atractylodes rhizome has CDCC to oncocyte, can reduce the rate of increase of oncocyte, lowers the aggressive of tumor tissue, improves the ability of the antitumor reaction of body.Baizhu volatile oil has inhibitory action to mouse EC, lymphosarcoma ascitic type, the cancer of the esophagus (Eca109), sarcoma 180 etc.Atractylodes lactone B lumbar injection is to the murine sarcoma people.Also there is remarkable inhibitory action.< < property of medicine opinion > > carries it: monarch, taste is sweet, pungent, nontoxic.The large wandering arthritis of energy master, diarrhea due to disorder of qi for many years, trusted subordinate's distending pain, the broken place food that disappears, appetizing, removes sputum, removes fever and chills, under stopping, lets out.Interarea light is happy, preserves youthful looks, and de-black.The swelling of harnessing the river is full, tells to vomit contraryly, and crymodynia in abdomen, vomits and diarrhoea incessantly, and the cold dysentery of stomach Qi deficiency.

The dried rhizome of rehmannia: the dried rhizome of rehmannia is also radix rehmanniae recen, the fresh or dry piece root of Scrophulariaceae herbaceos perennial glutinous rehmannia Rehmannia glutinosa Libosch..Heat-clearing, promote the production of body fluid, moisturize, laxation, the broken stasis of blood, raw new, pain relieving, menstruation regulating, the metal-inflicted wound stasis of blood, cool blood, hemostasis; The effect of fresh rehmannia root and radix rehmanniae recen is different.Fresh rehmannia root clearing heat and promoting fluid, can stop blooding and cool blood, is often for consumption of YIN caused by febrile disease, the illnesss such as haematemesis, abscess of throat, the deep red polydipsia of tongue, a spot dermexanthesis and nosebleed heat.With respect to fresh rehmannia root, radix rehmanniae recen is heat clearing and blood cooling, also can promote the production of body fluid, and all right yin-nourishing is used for treating yin asthenia generating intrinsic heat, hectic fever due to yin labor heat, the deep red polydipsia of tongue, sends out the problems such as spot dermexanthesis.The dried rhizome of rehmannia is cold in nature, and function is enriching yin and nourishing kidney.Not only promote the production of body fluid to quench thirst and heat clearing and blood cooling, also to metrorrhagia, irregular menstruation, fetal irritability, constipation etc., have effect, every blood system to have the people of thermal burn the moon, can often take.If want to treat warm heat disease, can do qingying decoction with the dried rhizome of rehmannia; If the later stage for the treatment of warm disease, because waste heat does not also disappear to the greatest extent, should be used for boiling Qinghao Biejia Tang the dried rhizome of rehmannia; In addition, for blood-head poison, contain, macula purple is black, and the serious heat of warm heat disease enters the symptom of ying blood, can take the Sisheng Wan that the dried rhizome of rehmannia is made; The general nourishing Yin and promoting production of body fluid of wanting treats that interior heat quenches one's thirst with constipation, should eat the once liquid soup that the dried rhizome of rehmannia boils.

The root bark of white mulberry is the root skin of moraceae plants mulberry Morus alba L..Main product in Anhui, the ground such as Henan, Zhejiang, Jiangsu, Hunan.Effect: removing heat from lung and relieving asthma, inducing diuresis for removing edema.For lung heat, cough and breathe heavily, the edema of the face, the diseases such as difficult urination.< < property of medicine opinion > >: make, flat.Can control lung qi and breathe heavily completely, aqueous vapor edema, main wound is exhausted, dredging water passages, the aqueous vapor that disappears, the headache of consumptive disease visitor heat, interior tonifying for the deficiency.< < Japan hanako materia medica > >: temperature, in tune, lower gas.Dissolving phlegm is quenched the thirst, sharp intestine and small intestine, and appetizing, lower food, kills abdomen and hides worm, and only cholera is vomited and diarrhoea.

Hawthorn, containing multivitamin, crataegolic acid, tartaric acid, citric acid, malic acid etc., also contains the mineral matters such as flavonoids, lactone, carbohydrate, protein, fat and calcium, phosphorus, iron, and contained lipolytic enzyme can promote the digestion of fat food.Promote gastric secretion and increase the functions such as stomach endoenzyme element.The traditional Chinese medical science thinks, hawthorn has that long-pendingization of disappearing is stagnant, convergence only dysentery, the effect such as activate blood circulation and disperse blood clots.Cure mainly the diseases such as eating accumulation, chest diaphragm ruffian are full, the amenorrhoea of hernia blood stasis.In hawthorn, contain the drug ingedients such as mountain terpene and brass class, there is significant hemangiectasis and hypotensive effect, there is the function that strengthens cardiac muscle, arrhythmia, adjusting blood fat and cholesterol level, hawthorn has the effect activating blood circulation and dispersing blood clots, contribute to remove local extravasated blood state, traumatic injury is had to auxiliary curative effect; The generation of free radical is blocked and reduced to the substances such as the flavonoids that hawthorn is contained and vitamin C, carrotene, can strengthen the immunity of body, has anti-aging, anticancer effect; In hawthorn, having relievings asthma reduces phlegm, the composition of anti-bacteria, treatment abdominal pain diarrhea.

Aster Latin formal name used at school: Tatarian Aster Root.Warm in nature, bitter, pungent.Moistening lung to lower qi; Preventing phlegm from forming and stopping coughing.Main cough; Deficiency syndrome of the lung labor is coughed; Consumptive lung disease lung carbuncle; Cough vomiting of pus and blood; Difficult urination.Breath with cough for phlegm, new chronic cough is coughed more, the labor hemoptysis of coughing.Decoction is oral can increase anesthetized rabbit and rats breathing road secretion and tool phlegm-dispelling functions.Its saponin and benzene and methanolic extract all have phlegm-dispelling functions.Its decoction draws and has coughed remarkable antitussive effect cat ammonia spraying; In its root alcohol extract, the colourless needle crystals of isolated one also has antitussive effect to mouse cough.Aster uranidin has diuresis.Its decoction obviously suppresses influenza virus in chick embryo allantois, resists in addition the effect of pathogenic fungus.Therefrom isolated table one freidelin alcohol has antitumaous effect to EC.This product has strong haemocylolysis containing saponin., the positive > > of < < book on Chinese herbal medicine: aster, pungently can enter lung, bitter can sending down abnormally ascending, therefore control cough with dyspnea, asthma due to excessive phlegm, only the real gas of lung is stopped up, or fire-evil punishment gold and the person that causes pyohemoptysis, be available it.

Reed rhizome is sweet, cold.Gui Jing: return lung channel, stomach warp.Function: clearing heat and promoting fluid, relieving restlessness, preventing or arresting vomiting, diuresis.Cure mainly: for pyreticosis polydipsia, gastropyretic vomiting, cough with lung heat, lung carbuncle pyemesis, heat, drench puckery pain.Cough with lung heat, lung carbuncle pyemesis.This product enters the kind clear lung heat thoroughly of lung channel, with controlling cough with lung heat, often joins the root of large-flowered skullcap, fritillaria thunbergii, snakegourd etc. medicinal.If control cough due to wind-heat evil, can join mulberry leaf, chrysanthemum, semen armeniacae amarae etc. medicinal, as Sang Ju Yin (< < warm disease bar is distinguished > >).If control lung carbuncle pyemesis, the use such as polygamy coix seed, Semen Benincasae, as weijing decoction (< < prescriptions worth thousand gold > >).

Cymose buckwheat rhizome is polygonaceae plant, another name duck wheat, wild bridge buckwheat, day buckwheat.It is cool in nature, and taste is pungent, bitter, has effect clearing heat and detoxicating, promoting blood circulation and removing blood stasis, invigorating spleen to remove dampness.Cymose buckwheat rhizome all has inhibitory action to staphylococcus aureus, streptococcus pneumonia, Escherichia coli, Pseudomonas aeruginosa, and liquor-saturated dose of effect is greater than aqua.Separately there is report; cymose buckwheat rhizome and each separating part thereof are without vitro antibacterial activity; different times lumbar injection cymose buckwheat rhizome medicinal extract 83mg/kg before infecting, has significant protective effect to abdominal cavity infection staphylococcus aureus mouse, but is infecting simultaneously or unprotect effect of medication after infecting.

Balloonflower root: bitter; Pungent; Property is put down.A surname's lung, eliminate the phlegm, relieve sore throat, apocenosis, sharp the five internal organs, fill blood, mend the exhaustion or lesion of the five internal organs, foster the spirit of nobility.Coughing with a lot of sputum, abscess of throat, lung carbuncle pyemesis, fullness in the chest and hypochondriac pain, dysentery stomachache, aphthae, red eye, swell pain, uroschesis.For coughing with a lot of sputum, uncomfortable in chest not smooth, pharyngalgia, hoarsen, lung carbuncle pyemesis, sore purulence does not become to burst.Balloonflower root is China tradition parts of generic medicinal plants, and the functions such as effect has a surname's lung, eliminates the phlegm, relieve sore throat, apocenosis, cure mainly the symptoms such as coughing with a lot of sputum, abscess of throat.Medicine-food two-purpose, demand is larger.< < property of medicine opinion > >: control the inferior dysentery, broken blood, removes pneumatosis, disappears and gathers, sputum, and main lung heat shortness of breath is coughed contrary, except crymodynia in abdomen, in master, dislikes and pediatric epilepsy scared.< < Japan hanako materia medica > >: lower all gas, only choleraic myospasm, trusted subordinate's distending pain, mends the exhaustion or lesion of the five internal organs, foster the spirit of nobility, evil removing is warded off temperature, qi-restoratives dissolving phlegm, broken abdominal mass, the apocenosis of nourishing blood, leaks and larynx numbness in mending.

Exocarpium Citri Rubrum is pungent, bitter, temperature.Return lung, the spleen channel.Loose cold, eliminating dampness, sharp gas, dissolving phlegm.For cough due to wind-cold evil, the larynx phlegm of itching is many, and dyspepsia is got sick from drinking too much wine, and the jailbird that vomits is vexed.< < medicineization justice > >: Exocarpium Citri Rubrum, pungently can walk crosswise dissipating bind, the bitter decline of keeping straight on, is sharp gas key medicine.Lid is controlled phlegm and must be regulated the flow of vital energy, the self-healing of gas profit phlegm, thus with entering lung spleen, main all phlegm diseases, merit occupies on all phlegm medicines.Assistant caulis bambusae in taenian, to treat heat oh, helps rascal to lead stagnant gas, real in same rhizoma atractylodis, the flat stomach of the bark of official magnolia, closes Bulbus Allii Fistulosi, the wet heresy of Chinese ephedra exterior cold, the essence derived from food that disappears, and relieving alcoholism, preventing or arresting vomiting is told, and opens chest diaphragm ruffian plug, can push away Chen Zhixin, and the power that all pungent loose hardship is fallen is also.Herbal classic is met former > >: the many phlegm of the special main lung cold cough of Exocarpium Citri Rubrum, deficient side multiplex it, the gas of so coughing is for a long time let out, non-institute is suitable again.> > is wanted in the bun of < < medical center: Exocarpium Citri Rubrum specially enters lung, holds concurrently to deliver.White in peeling, lighter empty floating, also removes the evil ear of lung.In the Li Shizhen (1518-1593 A.D.) < < of Ming Dynasty Compendium of Materia Medica > >, record: " Exocarpium Citri Rubrum good merchantable brand, has red white point in its flesh, sharp gas, reduce phlegm, cough-relieving merit is doubly to its medicine.。。Its merit Chen Yuliang of healing." the < < of Qing Dynasty A Supplement to the Compendium of Materia Medica > > carries: " and Exocarpium Citri Rubrum is controlled phlegm syndrome, disappear greasy, help digestion, sober up, wide in, separate crab poison." < < Chinese medicine voluminous dictionary > > says: " huazhou orange, nature and flavor acrid, bitter, warm, function for reducing phlegm, regulate the flow of vital energy, invigorating the spleen, help digestion, control in the heart that phlegm is stagnant, cough and asthma, vomiting hiccup, eating accumulation." < < Pharmacopoeia of People's Republic of China > > (nineteen ninety version) year: " Exocarpium Citri Grandis acrid, bitter, warm, return lung the spleen channel, tool is loose cold, eliminating dampness, sharp gas, dissolving phlegm function, and for cough due to wind-cold evil, larynx, itching, phlegm is many, dyspepsia is got sick from drinking too much wine, the nauseating ruffian of vomitting is vexed." clinical practice proves, tuberculosis, bronchitis, long-term stomachache, relieving cough and reducing sputum etc. is had to unique curative effect.

Semen Benincasae taste is sweet, and flat, moistening lung, reduces phlegm, the carbuncle that disappears, Li Shui.Control phlegm-heat cough, lung carbuncle, acute appendicitis, gonorrhoea, oedema, beriberi, hemorrhoid, nasal surface wine Zha.< < Japan hanako materia medica > >: peeling skin wind is shelled black Shao-, profit skin.< < detailed outline > >: control acute appendicitis.Control cough with slight fever, dysphoria, squamous and dry skin on the chest is to be lung carbuncle: reed stem (cut, two liters, boil and get five liters and go dregs with water two bucket), half liter of coix seed, 30 pieces, peach kernel, half liter of melon lobe (current multiplex Semen Benincasae).Upper four tastes fritter, and in interior reed juice, boil and get two liters, take one liter, when telling as purulence.(< < Synopsis Golden Chamber > > a thousand pieces of gold weijing decoction).

The root of straight ladybell clearing heat and nourishing yin, moistens the lung and relieve the cough.Cure mainly tracheitis, pertussis, cough with lung heat, coughs up phlegm yellow thick.The root of straight ladybell has the merit of Yin-nourishing and body fluid promoting, clearing heat and cooling blood, Combined with Radiotherapy chemotherapy is for tumor patient, especially to patients with advanced cancer blood depletion cloudy lose, the lung cancer of Lung-Yin deficiency, the postoperative deficiency of both qi and yin of tumor in digestive tract or the dry person of the withered liquid in Tianjin that causes because of radiotherapy impairment of yin, there is good curative effect.According to ancient literature, record, forefathers' the root of straight ladybell used, is adenophora tetraphylla.To the Qing Dynasty be loaded with the root of straight ladybell Fen Nan, north two kinds.It is generally acknowledged that two medicine effects are similar, all belong to yin-nourishing drug, there is nourishiing yin to clear away the lung-heat, the effect of reinforcing stomach reg fluid.So adenophora tetraphylla claims again large the root of straight ladybell, RADIX ADENOPHORAE, and its shape is thick, and matter is more loose, and effect is poor, and speciality, in entering " lung ", is partial to lung heat clearing away, sputum eliminating cough-relieving; Radix glehniae, claims again RADIX GLEHNIAE, slice ginseng, and its shape is elongated, the hard density of matter, and effect is better, and speciality is in entering " stomach ", and relatively nourishing Yin and promoting production of body fluid quenches the thirst, and saying is different.Modern study radix glehniae, containing alkaloid, volatilization wet goods, has the effects such as the body temperature of reduction, analgesia, cardiac stimulant; Radix glehniae, containing flavones, saponin etc., has and eliminates the phlegm, resists the effects such as true stone, cardiac stimulant.The adenophora tetraphylla replenishing the vital essence and removing heat moistening lung for removing phlegm treatment deficiency of Yin chronic cough consumptive disease phlegm blood cough caused by dryness phlegm of coughing is few; Abnormal heat larynx numbness (moistening the lung and relieve the cough).Radix glehniae stomach-Yin deficiency body fluid deficiency dry throat and mouth (nourishing the stomach to improve the production of body fluid).The present invention's the root of straight ladybell used, all guide the root of straight ladybell.

Fruit of Chinese magnoliavine temperature; Sour, sweet; Return lung, the heart, kidney channel; Restrain astringent or styptic treatment for spontaneous sweating, nourishing generate fluid, kidney calming.For the void of coughing for a long time, breathe heavily, emission, enuresis frequent micturition, endless diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, the feeble pulse of losing heart, interior heat is quenched one's thirst, palpitation and insomnia.< < Bencao Jingshu > > carries: the main beneficial gas person of the fruit of Chinese magnoliavine, and all gas of lung master, acid can be received, and is just entering lung tonifying lung, therefore beneficial gas is also.Its main cough with dyspnea person, the deficiency of vital energy is above stopped up and is not returned unit, and sour flavor having the property of astringing, takes the photograph gas and returns unit, and cough with dyspnea is from removing.Internal lesion caused by overexertion is won thin, tonifying for the deficiency, reinforcing yin essence, beneficial man's essence.< < does not record > > and supports the five internal organs, heat extraction, flesh person in raw the moon, the special kidney tonifying of the fruit of Chinese magnoliavine, the tonifying five zang organs of holding concurrently, kidney storing essence, essence is contained cloudy strong, receipts are taken the photograph vital qi and are returned unit, and public region is warm, digesting food, steam waste matter and change precise and tiny, smart spontaneous, essence is raw cloudy long, therefore main as above all diseases also.

Date: tonifying middle-Jiao and Qi, nourishing blood and tranquilization.Few for insufficiency of the spleen food, weak loose stool, hysteria of womam.According to an external clinical studies show: eat continuously the patient of date, Health restoration is faster more than 3 times than eating merely vitamin medicament.The CAMP that red date is contained, is the essential composition of human body cell energetic supersession, can strengthen muscular strength, eliminates fatigue, hemangiectasis, increase myocardial contractive power, improve myocardial nutrition, to preventing and treating disease of cardiovascular system, has good effect; Traditional Chinese medicine theory thinks, red date has the effects such as qi-restoratives benefit gas, nourishing blood and tranquilization, strengthening the spleen and stomach, is the good health nutrients of patient such as weakness of the spleen and the stomach, insufficiency of vital energy and blood, lassitude, insomnia and dreamful sleep.Red date has good therapeutic effect to illnesss such as chronic hepatitis, cirrhosis, anaemia, anaphylactoid purpuras; Red date contains triterpene compound and CAMP, has stronger anticancer, anti-allergic effects.1. < < herbal classic > >: " main trusted subordinate's perverse trend, supports spleen in peace, help 12 warps.Flat stomach Qi, logical nine orifices, mends weak breath, few body fluid, not enough, frightened in body, heaviness of limbs, and hundred medicines.

Specific embodiment 1:

First, by sealwort preparation, stir-fry.

Again by all the other raw materials tubers of dwarf lilyturf, the dried rhizome of rehmannia, Poria cocos, Radix Codonopsis, aster, reed rhizome, the root bark of white mulberry, heart of a lotus seed benevolence, the bighead atractylodes rhizome, cymose buckwheat rhizome, balloonflower root, Exocarpium Citri Rubrum, hawthorn, Semen Benincasae, the root of straight ladybell, the fruit of Chinese magnoliavine, date, extracts concentrated granulation agent, pulvis or paste.

The sealwort that mixing has been fried and the extract of other raw materials, ultraviolet radiation for sterilizing and disinfecting pack, directly can take after mixing it with hot water during use.

Specific embodiment 2:

Get sealwort 5000g and clean, get the sealwort obtaining and clean, the airing time, at 7-12 hour, parches; Be cut into thin slice, put a pot interior water proof and steam 30-60 minute at 80-100 ℃, then dry; After drying, repeat again to steam once, dry; Then put into large iron pan and stir-fry, first downwards backward upper, firmly want evenly, when sealwort color starts blackout, start the moulding in 30-45 minute that stir-fries of little fire; When color becomes pitchy, after taking out, naturally dry; By the surplus stock 1500g tuber of dwarf lilyturf, dried rhizome of rehmannia 1000g, Poria cocos 1000g, Radix Codonopsis 1000g, aster 1200g, reed rhizome 1000g, root bark of white mulberry 1000g, heart of a lotus seed benevolence 1300g, bighead atractylodes rhizome 1400g, cymose buckwheat rhizome 1000g, balloonflower root 1000g, Exocarpium Citri Rubrum 1300g, hawthorn 1000g, Semen Benincasae 1300g, the root of straight ladybell 1000g, fruit of Chinese magnoliavine 1000g, date 1100g, cleans impurity elimination, dry, be ground into particle, soak 1 hour; Soaked bulk drug is put to boiling secondary in multi-function extractor; Add up for the first time the water of 10 times of amounts of medicinal material, decoct 1.5～2 hours, get decocting liquid, filter; Add up for the second time the water of 7 times of amounts of medicinal material, decoct 1～1.2 hour, get twice decocting liquid and mix, filter; The filtrate of filtration is inserted in economic benefits and social benefits vacuum concentrator to the concentrate that while being concentrated into 90 ℃, relative density is 1.05, set to 0～5 ℃ of deepfreezes 24 hours; Refrigeration liquid is added to 0.3% filter aid diatomite, filter, filtrate is inserted in economic benefits and social benefits vacuum concentrator again, is concentrated into every 1ml containing 1g crude drug amount, adds the agent of dextrin granulation.The sealwort of having fried is mixed with the granule of making, ultraviolet disinfection, packs and get final product again.

Specific embodiment 3:

Get sealwort 4000g and clean, get the sealwort obtaining and clean, the airing time, at 7-12 hour, parches; Be cut into thin slice, put a pot interior water proof and steam 30-60 minute at 80-100 ℃, then dry; After drying, repeat again to steam once, dry; Then put into large iron pan and stir-fry, first downwards backward upper, firmly want evenly, when sealwort color starts blackout, start the moulding in 30-45 minute that stir-fries of little fire; When color becomes pitchy, after taking out, naturally dry; By the surplus stock 1100g tuber of dwarf lilyturf, dried rhizome of rehmannia 1300g, Poria cocos 1000g, Radix Codonopsis 1000g, aster 1000g, reed rhizome 1100g, root bark of white mulberry 1000g, heart of a lotus seed benevolence 1200g, bighead atractylodes rhizome 1000g, cymose buckwheat rhizome 1000g, balloonflower root 1000g, Exocarpium Citri Rubrum 1200g, hawthorn 1200g, Semen Benincasae 1100g, the root of straight ladybell 1200g, fruit of Chinese magnoliavine 1000g, date 1200g, puts it in 10 times of water gagings and soaks.Drop into multi-function extractor and extract twice, add for the first time 8-10 times of water gaging and decoct 1-2 hour, add for the second time 4-8 times of water gaging and decoct 1-2 hour, merge twice decocting liquid, filter to get filtrate; Heating is concentrated into powder, then puts into baking oven inner drying powdered, and hybrid packed with the good sealwort of frying after ultraviolet radiation for sterilizing and disinfecting, during use, direct boiling water is taken after mixing it with water.

Pharmacology toxicity test

Experimental example 1: acute toxicity test of the present invention

One, test material: animal: Kunming mouse, body weight 18-25g, male and female half and half, Shandong University's biology laboratory breeding.Medicine: the present invention's (all raw material mixes decoction 2 times, merges and filters, taking liquid) is containing 0.0365mg/ml.

Two, method:

1, LD50 calculates: adopt improvement karber's method, mouse is divided into 5 groups at random, 10 every group, male and female half and half, dissolve adding distil water of the present invention, are made into Cmax, by the administration of the maximum permission capacity of mouse, institute is followed successively by 18,14.4 to dosage by crude drug amount, 11.5,9.2,7.4 (g.kg-1), in animal fasting (can't help water) after 18 hours, administration at twice in one day (interval half an hour), each 0.5ml, observes animal dead situation.

2, maximum tolerated dose is measured (MTD value): get 20 of mouse, each 10 of male and female.Adding distil water of the present invention is dissolved, be made into maximum concentration, by the maximal tolerance dose of animal, to inject, fill with hello device and can twitch and be as the criterion.In animal fasting (can't help water) after 18 hours, administration at twice in one day (interval half an hour), each 0.5ml (every ml is containing crude drug 0.36g), total dose is 18g crude drug/kg.d, 300 times of quite clinical adult 50Kg body weight consumption.Continuous Observation 7 days after administration.

Three, result of the test:

LD50 calculate in when giving mouse with maximum acceptable concentration and maximum permission capacity (18g/Kg.d), have no dead mouse, do not measure LD50, ask only maximum tolerated dose, in 7 day observation period, its appetite of animal, activity, hair color, the state of mind etc. are all normal, grow normally, there are no death.Select 300 times of doses that are equivalent to clinical dosage, and have no adverse reaction, show that acute toxicity is minimum, MTD>18g/Kg.d.

Experimental example 2: the result of the test of acute toxicity and long term toxicity

Acute toxicity test: give the present invention by the disposable gavage of small white mouse, maximum concentration 35%, maximum gavage capacity 0.4ml/10g, dosage 14g/kg (every g medicinal powder is equivalent to 10g crude drug), Continuous Observation 7 days, do not find any toxic reaction, because concentration and dosage cannot increase, therefore fail to measure the LD50 of this medicine.Maximum tolerance determination: with maximum concentration, maximum gavage capacity, mice lavage administration 3 times, 5 hours, interval, then Continuous Observation 7 days, none example is dead.Medicinal powder dosage is >42g/kg. day (every g medicinal powder is equivalent to 10g crude drug), by kg body weight, calculate the clinical consumption per day that is equivalent to be grown up 420 times.

Long term toxicity test: whether produce toxic reaction for observing long-term prescription, give respectively rat the present invention and raise clothes, by adult 70 times of clinical consumption per day and 35 times (being 7g/kg/ day and 3.5g/kg/ day), to give and feed 8 weeks continuously, the behavior, feed, the body weight that have no rat occur extremely, with control group ratio, routine blood test, hepatic and renal function, various important organs are all without abnormal change, within the scope of institute's dosage, do not found any toxicity of the present invention.By the acute and chronic toxicity test confirmation of animal, safe range of the present invention is larger, is a kind of safe and reliable health products.

Clinical trial:

Laryngeal cough is common clinically illness, means the cough that pharyngolaryngitis causes.This group case refers to the cough of acute and chronic sphagitis for trouble more.I treat laryngeal cough by institute's application invigorating the spleen moistening lung King solomonseal rhizome tea, and satisfactory effect, is now summarized as follows:

1 clinical data

1.1 physical data:

Treatment group: 40 examples are all clinic case, the wherein male sex's 17 examples, women's 23 examples; Minimum 6 years old of age, maximum 65 years old; 20 years old following 3 examples, 21～40 years old 13 example, 41～60 years old 16 example, 61 years old above 8 example; The course of disease is the shortest 2 days, the longest 3 months.Control group 40 examples, wherein male 16 examples, female's 24 examples; Minimum 5 years old of age, maximum 67 years old; 20 years old following 2 examples, 21～40 years old 14 example, 41～60 years old 13 example, 60 years old above 01 example; The course of disease is the shortest 3 days, the longest 2 months.

1.2 sings and symptomses: clinical symptoms are with cough, the pharynx sense as ant row or phlegm resistance throat of itching is main.Check that pharyngeal visible mucous hyperemia or pharynx rear wall have lymph foilicie hyperplasia.Get rid of the cough that other illness causes.

1.3 Chinese medical discrimination classification:

Chinese medical discrimination is divided into: syndrome of wind-cold attacking lung: cough low voice speaking, the thin look of coughing up phlegm is white, and pharynx is itched, with exterior syndrome due to wind-cold.This group has 2 examples (accounting for 5.56%); Syndrome of wind-heat invading lung: cough rough, cough up phlegm sticky white or yellow, pharyngalgia pharynx is itched, or it is mute to cough trachyphonia, with wind-heat illness that has not attacked the vital organs of the human body.This group has 4 examples (accounting for 11.12%); > > dryness evil impariment of the lung card: the few phlegm of dry cough or cough up phlegm not well, nasal cavity dryness dry throat, pharynx is itched, red tip of tongue, the few Tianjin of the thin Huang of tongue, thready rapid pulse.This group has 7 examples (accounting for 19.45%); The strongly fragrant lung card of phlegm heat: cough, the how thick Huang of phlegm, swallows the dry of itching, dysphoria with smothery sensation, red tongue body, yellow,greasy and thin fur, slippery and rapid pulse.This group has 6 examples (accounting for 16.67%); Syndrome of liver fire invading lung: cough and dyspnea with choke battle array is done, dragging pain between the chest and hypochondrium while coughing, dry throat pharynx is itched, the yellow few Tianjin of thin lingual fur, wiry and frequent pulse.This group has 5 examples (accounting for 13.89%); Phlegm dampness in lungs card: cough low voice speaking turbidly, phlegm polychrome is white, and a mouthful sticky pharynx is itched, epigastric oppression and anorenia uncomfortable in chest, white and greasy fur, arteries and veins moistens cunning.This group has 3 examples (8.33%); Deficiency syndrome of the lung card: the few phlegm of sick dry cough for a long time, phlegm is sticky white, and it is mouthful dry that dry throat is itched, feverishness in palms and soles, the red few tongue of tongue, thready rapid pulse.Or sound of cough being low and weak, phlegm is rare clearly in vain, refreshing tired weak breath, and sweat is many, pale tongue with white fur, arteries and veins is thin and delicate.This group has 9 examples (accounting for 25%).

1.4 doctor trained in Western medicine clinical stages:

Belong to acute laryngopharyngitis 8 examples (accounting for 20%); Chronic simple sphagitis 9 examples (22.5%); Chronic plump pharyngitis 7 examples (accounting for 17.5%); Atrophic or drying property sphagitis 16 examples (accounting for 40%).

2 methods of treatments

2.1 observation groups: give invigorating the spleen moistening lung King solomonseal rhizome tea of the present invention according to differentiation of symptoms and signs for classification of syndrome.The composition of invigorating the spleen moistening lung King solomonseal rhizome tea: sealwort 50g, the tuber of dwarf lilyturf 11g, dried rhizome of rehmannia 13g, Poria cocos 10g, Radix Codonopsis 10g, aster 12g, reed rhizome 11g, root bark of white mulberry 14g, heart of a lotus seed benevolence 12g, bighead atractylodes rhizome 11g, cymose buckwheat rhizome 12g, balloonflower root 12g, Exocarpium Citri Rubrum 12g, hawthorn 13g, Semen Benincasae 11g, the root of straight ladybell 12g, fruit of Chinese magnoliavine 12g, date 11g, adds boiling water water 600ml every morning, steep and drink after 30 minutes, wrap every day 2, and 6d was 1 course for the treatment of.

2.2 control groups: application antibiotic, as one of them oral or intramuscular injection such as penicillin, erythromycin, cephalexin, spiramvcin, Tarivid, Ciprofloxacins; Coordinate relieving cough and reducing sputum liquid medicine, as brown mixture, mixture of ammonium chloride, CHUANBEI PIPA GAO, Fel Serpentis et Bulbus Fritillariae Cirrhosae Liquidus, magical pectoral syrup, disappear cough breathe heavily etc. wantonly a kind oral.

3 observation of curative effect

3.1 criterions of therapeutical effect: cure: in 2 courses for the treatment of of medication, patient's symptom and sign disappear completely; Effective: after 2 courses for the treatment of of medication, patient's symptom and sign are clearly better, part disappears; Effective: after 2 courses for the treatment of of medication, patient clinical symptom is improved, and sign take a favorable turn; Invalid: after 2 courses for the treatment of of medication, patient's symptom and sign change little.3.2 results for the treatment of: observation group cures 8 examples (accounting for 22.22%), wherein syndrome of wind-heat invading lung 2 examples (accounting for 5.56%), the dryness evil impariment of the lung is demonstrate,proved 1 example (accounting for 2.78%), syndrome of liver fire invading lung 1 example (accounting for 2.78%), the deficiency syndrome of the lung is demonstrate,proved 4 examples (accounting for 11.11%); Effective 9 examples (accounting for 25%), wherein wind-heat affecting lung 1 example (accounting for 2.78%), the dryness evil impariment of the lung is demonstrate,proved 2 examples (accounting for 5.56%), the strongly fragrant lung of phlegm heat is demonstrate,proved 1 example (accounting for 2.78%), syndrome of liver fire invading lung 2 examples (accounting for 5.56%), phlegm dampness in lungs is demonstrate,proved 1 example (accounting for 2.78%), and the deficiency syndrome of the lung is demonstrate,proved 2 examples (accounting for 5.56%); Effective 14 examples (accounting for 38.89%), wherein syndrome of wind-cold attacking lung 2 examples (accounting for 5.56%), syndrome of wind-heat invading lung 1 example (accounting for 2.78%), the dryness evil impariment of the lung is demonstrate,proved 3 examples (accounting for 8.33%), the strongly fragrant lung of phlegm heat is demonstrate,proved 3 examples (accounting for 8.33%), syndrome of liver fire invading lung 2 examples (accounting for 5.56%), phlegm dampness in lungs is demonstrate,proved 1 example (accounting for 2.78%), and the deficiency syndrome of the lung is demonstrate,proved 2 examples (accounting for 5.56%); Invalid 5 examples (accounting for 13.89%), wherein the dryness evil impariment of the lung is demonstrate,proved 1 example (accounting for 2.78%), the strongly fragrant lung of phlegm heat is demonstrate,proved 2 examples (accounting for 5.56%), and phlegm dampness in lungs is demonstrate,proved 1 example (accounting for 2.78%), and the deficiency syndrome of the lung is demonstrate,proved 1 example (accounting for 2.78%).Total effective rate 86.11%.Control group: cure 7 examples (accounting for 21.88%), wherein syndrome of wind-cold attacking lung 1 example (accounting for 3.13%), syndrome of wind-heat invading lung 2 examples (accounting for 6.25%), the strongly fragrant lung of phlegm heat is demonstrate,proved 1 example (accounting for 3.13%), phlegm dampness in lungs is demonstrate,proved 1 example (accounting for 3.13%), and the deficiency syndrome of the lung is demonstrate,proved 2 examples (accounting for 6.25%); Effective 9 examples (accounting for 28.13%), wherein syndrome of wind-heat invading lung 3 examples (accounting for 9.38%), the dryness evil impariment of the lung is demonstrate,proved 1 example (accounting for 3.13%), the strongly fragrant lung of phlegm heat is demonstrate,proved 2 examples (accounting for 6.25%), syndrome of liver fire invading lung 1 example (accounting for 3.135), the deficiency syndrome of the lung is demonstrate,proved 2 examples (accounting for 6.25%); Effective 5 examples (accounting for 15.63%), wherein syndrome of wind-cold attacking lung 1 example (accounting for 3.13%), the dryness evil impariment of the lung is demonstrate,proved 2 examples (accounting for 6.25%), and the strongly fragrant lung of phlegm heat is demonstrate,proved 1 example (accounting for 1.13%), and the deficiency syndrome of the lung is demonstrate,proved 1 example (accounting for 3.13%); Invalid 11 examples (accounting for 34.38%), wherein the dryness evil impariment of the lung is demonstrate,proved 1 example (accounting for 3.13%), the strongly fragrant lung of phlegm heat is demonstrate,proved 2 examples (accounting for 6.25%), syndrome of liver fire invading lung 3 examples (accounting for 9.38%), phlegm dampness in lungs is demonstrate,proved 2 examples (accounting for 6.25%), the deficiency syndrome of the lung is demonstrate,proved 3 examples (accounting for 9.38%), total effective rate 65.63%.2 groups of curative effect comparisons, learn and process by statistics, have significant difference (P<0.05).

4 discuss

Laryngeal cough belongs to the traditional Chinese medical science " larynx numbness ", " cough " category.Though cardinal symptom has cough, diseased region is at throat.Pharyngeal is the door of lung, the heresy of six external factors which cause diseases invasion and attack body, and pharyngeal standing in the breach, causes discomfort in the throat and coughs.Some case because of the infection of the upper respiratory tract, flu after illness that has not attacked the vital organs of the human body separate, lose cough pharynx and itch, cough with difficulty in expectoration, phlegm is few or without phlegm.The traditional Chinese medical science thinks that this is remaining evil love lung visitor pharynx, and chronic cough lung loses and makes moist, declare respectful not normal, due to throat air flue is unfavorable.

Throat is essential substances from water and cereals and the shared pathway of the gas of breathing, if eating and drinking without temperance, impairing the spleen and stomach, transporting mistake department, retention of water-damp in the body, accumulatively wet raise phlegm, the phlegm criminal of going up that wets, ties in discomfort in the throat and coughing of throat.In a word, laryngeal cough is many because spleen is wet, the dryness of the lung, and phlegm is tied due to the throat.The key of its treatment is spleen, lung, throat.Therefore, invigorating the spleen moistening lung King solomonseal rhizome tea, for the cause of disease, is taked invigorating the spleen moistening lung, the method for smooth throat to stop cough and obtain effect.Sealwort sugariness is flat, returns spleen, lung; Kidney channel, has boosting qi and nourishing yin, invigorating the spleen, moistening lung, kidney benefiting functions.Be used for the treatment of weakness of the spleen and the stomach, fatigue and asthenia, dry food is few, deficiency syndrome of the lung cough caused by dryness, asthenia of essence and blood, the interior heat disease such as quench one's thirst.Boosting qi and nourishing yin, invigorating the spleen, moistening lung, the good medicine of kidney-nourishing.Curing mainly deficiency of Yin labor coughs; Xeropulmonary cough; Insufficiency of the spleen weak; The few dry of food; Quench one's thirst; Deficiency of the kidney soreness and weakness of waist and knees; Impotence and seminal emission; Tinnitus order is dark; Poliosis; The empty win of body is thin; Wind favus disease.Poria cocos, Exocarpium Citri Rubrum strengthening the spleen and reducing phlegm, to stop the source of producing phlegm, make phlegm so wet that to change, and its property is not warm dry, therefore consume the fraud of liquid without impairment of yin; The root of straight ladybell can moisten the lung and nourish yin, and air flue must be moistened, and dry throat, pharynx are itched and removed; Aster embellishes but not dry, relieving cough and reducing sputum; The fruit of Chinese magnoliavine yin-nourishing of astringing the lung, both can support lung yin born fluid, again can purging intense heat relieve sore throat; Balloonflower root a surname lung relieve sore throat is relieving cough and reducing sputum; And can clearing heat and detoxicating relieve sore throat.All medicines coordinate, and can stop pathogeny, can reach disease institute by medicine again, therefore how desirable effect.

Specific embodiment 1: recklessly, female, 45 years old, in first visit on April 23 in 2009.There is the few phlegm of dry cough in patient, the sticky difficulty of phlegm is coughed up, and pharynx was itched more than March.Once repeatedly went to a doctor in unit one belongs to clinic, and successively took erythromycin, medecamycin, chlorpheniramine, mixture of ammonium chloride, brown mixture etc., symptom is improved not obvious, and changes the place of examination in undergraduate course.Disease is seen: cough, and pharynx is itched and is coughed, and the few show bubble of phlegm, is difficult to bring up, Blushing while coughing play, tears all go out, heavy lose while coughing and drown, and companion's dry throat is uncomfortable in chest, spiritlessness and weakness, indigestion and loss of appetite, sleep not good enough night, clear abundant urine, stool is tune still, and tongue is dark red, Tai Bai and doing, arteries and veins is thin and delicate.Have a medical check-up: T36.7 ℃, congestion of throat, swallows rear wall FH as seen, thorax is without deformity, cardiopulmonary are without extremely, have a blood test resemble, Chest X-rays, phlegm look for tulase, phlegm to cultivate all without anomaly.Because take medicine throughout the year, medicine is produced to resentment, suggestion replaces and takes Chinese medicine with health tea-drinking.

Give invigorating the spleen moistening lung King solomonseal rhizome tea, side use: sealwort 50g, the tuber of dwarf lilyturf 12g, dried rhizome of rehmannia 11g, Poria cocos 13g, Radix Codonopsis 10g, aster 12g, reed rhizome 11g, root bark of white mulberry 14g, heart of a lotus seed benevolence 12g, bighead atractylodes rhizome 11g, cymose buckwheat rhizome 12g, balloonflower root 12g, Exocarpium Citri Rubrum 12g, hawthorn 13g, Semen Benincasae 11g, the root of straight ladybell 12g, fruit of Chinese magnoliavine 13g, date 11g, adds boiling water water 600ml every morning, steep and drink after 30 minutes, wrap every day 2, and 6d adds each 15g of radix pseudostellariae, the tuber of dwarf lilyturf 1 course for the treatment of.Take after 6 days, the conscious pharynx of patient is itched and is obviously alleviated, and cough is alleviated, and phlegm is easy to bring up in vain.Enter 1 month, patient cough removes again, pharynx disappearances of itching, all diseases are improved, look into pharyngeal show mucous hyperemia and swallow rear wall FH all disappear.Follow up a case by regular visits to and within 1 year, have no recurrence.

Specific embodiment 2: together certain, man, 33 years old, teacher, because there being chronic pharyngitis, often feel throat and itch, retch, throughout the year cough, pharynx is itched and is coughed, and the few show bubble of phlegm, is difficult to bring up Blushing while coughing play, tears all go out, heavy lose and drown while coughing, and companion's dry throat is uncomfortable in chest, spiritlessness and weakness, indigestion and loss of appetite, sleep not good enough night, clear abundant urine, and stool is still adjusted, tongue is dark red, Tai Bai and doing, and arteries and veins is thin and delicate.Mood is gloomy, and complexion is very bad.Take medicine to produce throughout the year and repel, medicine is produced to resentment, upon somebody's introduction, with health tea-drinking, replace and take Chinese medicine.

Give invigorating the spleen moistening lung King solomonseal rhizome tea, side use: sealwort 40g, the tuber of dwarf lilyturf 13g, dried rhizome of rehmannia 11g, Poria cocos 13g, Radix Codonopsis 12g, aster 12g, reed rhizome 11g, root bark of white mulberry 14g, heart of a lotus seed benevolence 12g, bighead atractylodes rhizome 11g, cymose buckwheat rhizome 12g, balloonflower root 12g, Exocarpium Citri Rubrum 12g, hawthorn 13g, Semen Benincasae 11g, the root of straight ladybell 12g, fruit of Chinese magnoliavine 13g, date 11g, adds boiling water water 600ml every morning, steep and drink after 30 minutes, wrap every day 2, and 6d was 1 course for the treatment of.Second day just starts invigorating the spleen moistening lung, takes after 6 days, and the conscious pharynx of patient is itched and obviously alleviated, and cough is alleviated, and phlegm is easy to bring up in vain.Enter 1 month, patient cough removes again, pharynx disappearances of itching, all diseases are improved, look into pharyngeal show mucous hyperemia and swallow rear wall FH all disappear.Follow up a case by regular visits to and within 2 years, have no recurrence.

Claims

1. a sealwort invigorating the spleen moistening lung health protection tea, it is characterized in that, in described sealwort invigorating the spleen moistening lung health protection tea health protection tea, the parts by weight of various raw materials comprise: 10～50 parts of sealworts, 10～20 parts of the tubers of dwarf lilyturf, 10～20 parts, the dried rhizome of rehmannia, 10～20 parts, Poria cocos, 10～20 parts of Radix Codonopsis, 10～20 parts of asters, 10～20 parts of reed rhizomes, 10～20 parts of the root barks of white mulberry, 10～20 parts of heart of a lotus seed benevolence, 10～20 parts of the bighead atractylodes rhizomes, 10～20 parts of cymose buckwheat rhizomes, 10～20 parts of balloonflower roots, 10～20 parts of Exocarpium Citri Rubrums, 10～20 parts of hawthorn, 10～20 parts of Semen Benincasaes, 10～20 parts of the root of straight ladybell, 10～20 parts, the fruit of Chinese magnoliavine, 10～20 parts, date.

2. sealwort invigorating the spleen moistening lung health protection tea according to claim 1, it is characterized in that, in described sealwort invigorating the spleen moistening lung health protection tea, the parts by weight of various raw materials are: 20～40 parts of sealworts, 10～15 parts of the tubers of dwarf lilyturf, 10～15 parts, the dried rhizome of rehmannia, 10～15 parts, Poria cocos, 10～15 parts of Radix Codonopsis, 10～15 parts of asters, 10～15 parts of reed rhizomes, 10～15 parts of the root barks of white mulberry, 10～15 parts of heart of a lotus seed benevolence, 10～20 parts of the bighead atractylodes rhizomes, 10～20 parts of cymose buckwheat rhizomes, 10～20 parts of balloonflower roots, 10～20 parts of Exocarpium Citri Rubrums, 10～20 parts of hawthorn, 10～20 parts of Semen Benincasaes, 10～20 parts of the root of straight ladybell, 10～20 parts, the fruit of Chinese magnoliavine, 10～20 parts, date.

3. sealwort invigorating the spleen moistening lung health protection tea according to claim 1, it is characterized in that, in described sealwort invigorating the spleen moistening lung health protection tea, the parts by weight of various raw materials are: 10～30 parts of sealworts, 10～20 parts of the tubers of dwarf lilyturf, 10～20 parts, the dried rhizome of rehmannia, 10～20 parts, Poria cocos, 10～20 parts of Radix Codonopsis, 10～20 parts of asters, 10～20 parts of reed rhizomes, 10～20 parts of the root barks of white mulberry, 10～20 parts of heart of a lotus seed benevolence, 10～15 parts of the bighead atractylodes rhizomes, 10～15 parts of cymose buckwheat rhizomes, 10～15 parts of balloonflower roots, 10～15 parts of Exocarpium Citri Rubrums, 10～15 parts of hawthorn, 10～15 parts of Semen Benincasaes, the root of straight ladybell 10～, 15 parts, 10～15 parts, the fruit of Chinese magnoliavine, 10～15 parts, date.

4. a preparation method for sealwort invigorating the spleen moistening lung health protection tea as described in claim 1～3 any one, is characterized in that, the preparation process of described sealwort invigorating the spleen moistening lung health protection tea comprises following aspect:

A. the preparation of sealwort;

5. the preparation method of sealwort invigorating the spleen moistening lung health protection tea according to claim 4, is characterized in that, in described step a, gets the sealwort obtaining and cleans, and the airing time, at 7-12 hour, parches; Be cut into thin slice, put a pot interior water proof and steam 30-60 minute at 80-100 ℃, then dry; After drying, repeat again to steam once, dry; Then put into large iron pan and stir-fry, first downwards backward upper, firmly want evenly, when sealwort color starts blackout, start the moulding in 30-45 minute that stir-fries of little fire; When color becomes pitchy, after taking out, naturally dry.

6. the preparation method of sealwort invigorating the spleen moistening lung health protection tea according to claim 4, is characterized in that, in described step b, surplus stock is cleaned to impurity elimination, dries, and is ground into particle, soaks 1 hour; Soaked raw material is put to boiling secondary in multi-function extractor; Add up for the first time the water of 10 times of amounts of medicinal material, decoct 1.5～2 hours, get decocting liquid, filter; Add for the second time the water of 7 times of amounts of total amount, decoct 1～1.2 hour, get twice decocting liquid and mix, filter.

7. the preparation method of sealwort invigorating the spleen moistening lung health protection tea according to claim 4, it is characterized in that, in described step c, the filtrate of filtration is inserted in economic benefits and social benefits vacuum concentrator, the concentrate that while being concentrated into 90 ℃, relative density is 1.05, set to 0～5 ℃ of deepfreezes 24 hours; Refrigeration liquid is added to 0.3% filter aid diatomite, filter, filtrate is inserted in economic benefits and social benefits vacuum concentrator again, is concentrated into every 1ml containing 1g crude drug amount, then adds dextrin and puts into granulator and granulate.

8. the preparation method who treats according to claim 4 sealwort invigorating the spleen moistening lung health protection tea, is characterized in that, in described steps d, the particle that sealwort good frying is prepared with surplus stock mixes, and ultraviolet disinfection is packed and be get final product.

9. the preparation method of basis sealwort invigorating the spleen moistening lung health protection tea as described in claim 1～3 any one, it is characterized in that, when other raw materials of described sealwort invigorating the spleen moistening lung Antilipemic health tea are made pulvis, step is: other raw materials are put into 10 times of amount ethanol, heating and refluxing extraction 2 times, each 1～2 hour, No. 2 extracts are merged standing; The dregs of a decoction of the component raw medicinal material of more above-mentioned alcohol extract being crossed add 10 times of water gaging heating and refluxing extraction 2 times, each 1～2 hour, No. 2 extracts are merged standing; Above-mentioned two kinds of extracts are merged, and reclaiming after ethanol decompression, to put into inspissator concentrated, then puts into drying baker and be dried into powder, after ultraviolet radiation for sterilizing and disinfecting, merges packing with the good sealwort of frying.

10. the preparation method of sealwort invigorating the spleen moistening lung health protection tea according to claim 9, it is characterized in that: in above-mentioned concentration step, two kinds of extracts are merged, after recovery ethanol, reducing pressure, it is concentrated to put into inspissator, the concentrate that while being concentrated into 90 ℃, relative density is 1.05, set to 0～5 ℃ of deepfreezes 24 hours; Refrigeration liquid is added to 0.3% filter aid diatomite, filter, filtrate is inserted in economic benefits and social benefits vacuum concentrator again, is concentrated into every 1ml containing 1g crude drug amount.