CN105412858A - Syrup and preparation method thereof - Google Patents

Syrup and preparation method thereof Download PDF

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Publication number
CN105412858A
CN105412858A CN201510807566.XA CN201510807566A CN105412858A CN 105412858 A CN105412858 A CN 105412858A CN 201510807566 A CN201510807566 A CN 201510807566A CN 105412858 A CN105412858 A CN 105412858A
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parts
syrup
cough
rhizoma
radix
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岳海棠
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016Disaccharides, e.g. lactose, lactulose
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/062Ascomycota
    • A61K36/066Clavicipitaceae
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    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/16Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/346Platycodon
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/78Saururaceae (Lizard's-tail family)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969Polygonatum (Solomon's seal)
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    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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    • A61K36/906Zingiberaceae (Ginger family)
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    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

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Abstract

The invention relates to syrup. The syrup is prepared from, by weight, 17-30 parts of ginseng, 10-22 parts of radix polygonati officinalis, 11-22 parts of cordyceps militaris, 5-15 parts of ginkgos, 5-15 parts of almonds, 10-22 parts of rhizoma zingiberis, 9-21 parts of exocarpium citri grandis, 5-15 parts of cinnamon, 5-15 parts of licorice, 5-15 parts of folium mori, 5-15 parts of platycodon grandiflorum, 20-30 parts of dark plums, 5-15 parts of poria cocos, 5-15 parts of reed rhizome, 20-30 parts of houttuynia cordata, 200-300 parts of pure honey, 120-200 parts of rock candy, 60-100 parts of mature vinegar and 200-300 parts of water. The syrup has the advantages that all medicinal materials are combined organically and achieve a synergistic effect by means of grinding and decocting to prepare the syrup with the functions of relieving a cough and asthma and clearing away phlegm accumulated in a body. The syrup is convenient to take and obvious in effect.

Description

A kind of syrup and preparation method thereof
Technical field
The invention belongs to Chinese herbal and crude drugs preparations, be specifically related to a kind of syrup and preparation method thereof.
Background technology
Cough is the protectiveness respiratory reflex action that human body removes secretions in respiratory tract or foreign body.Although there is the one side that it is favourable, also have its disadvantageous effect, cough can be diffused into contiguous bronchia trachea pathological changes, aggravates disease.In addition, cough violent lastingly can affect rest, goes back easy consumption muscle power, and can cause the destruction of alveolar wall Elastic tissue, brings out emphysema, also can cause respiratory tract hemorrhage.
Cough is a kind of clinical common disease, although general cough is not serious to human body infringement, and seldom can rapid healing.In order to realize the object for the treatment of cough, the medicament that those skilled in the art adopts Chinese medicine, Western medicine etc. numerous, but the effect of current existing pharmaceutical treatment is not very desirable.
Summary of the invention
In order to solve the problems referred to above that prior art exists, the invention provides a kind of syrup for the treatment of cough and preparation method thereof, by each medical material in this invention is combined, boiled by grinding, it is made to play synergism, make a kind of syrup with relieving cough and relieving asthma purged body inner product expectorant, this syrup taking convenience, successful.
The technical solution adopted in the present invention is:
A kind of syrup, the weight portion of it component comprised and each component is as follows: Radix Ginseng 17-30 part; Rhizoma Polygonati Odorati 10-22 part; Cordyceps militaris (L.) Link. 11-22 part; Semen Ginkgo 5-15 part; Semen Armeniacae Amarum 5-15 part; Rhizoma Zingiberis 10-22 part; Exocarpium Citri Grandis 9-21 part; Cortex Cinnamomi 5-15 part; Radix Glycyrrhizae 5-15 part; Folium Mori 5-15 part; Radix Platycodonis 5-15 part; Fructus Mume 20-30 part; Poria 5-15 part; Rhizoma Phragmitis 5-15 part; Herba Houttuyniae 20-30 part; Pure Mel 200-300 part; Crystal sugar 120-200 part; Mature vinegar 60-100 part; Water 200-300 part.
The further optimization of component design of the present invention, the weight portion of it component comprised and each component is as follows: Radix Ginseng 22 parts; Rhizoma Polygonati Odorati 16 parts; Cordyceps militaris (L.) Link. 16 parts; Semen Ginkgo 10 parts; 10 parts, Semen Armeniacae Amarum; Rhizoma Zingiberis 16 parts; Exocarpium Citri Grandis 15 parts; Cortex Cinnamomi 10 parts; 10 parts, Radix Glycyrrhizae; 10 parts, Folium Mori; Radix Platycodonis 10 parts; Fructus Mume 25 parts; 10 parts, Poria; Rhizoma Phragmitis 10 parts; Herba Houttuyniae 25 parts; Pure Mel 250 parts; 166 parts, crystal sugar; 83 parts, mature vinegar; 250 parts, water.
Further, the preparation method of above-mentioned cough syrup is it is characterized in that: described preparation method comprises the following steps:
A, the Radix Ginseng of appropriate part, Rhizoma Polygonati Odorati, Cordyceps militaris (L.) Link., Semen Ginkgo, Semen Armeniacae Amarum, Rhizoma Zingiberis, Exocarpium Citri Grandis, Cortex Cinnamomi, Radix Glycyrrhizae, Folium Mori, Radix Platycodonis, Fructus Mume, Poria, Rhizoma Phragmitis and Herba Houttuyniae are worn into the coarse powder that particle diameter is 0.3-0.7cm respectively;
B, to grind in the coarse powder that obtains add water and mix to step a, coarse powder and decocting in water are opened by the big fire being greater than 110 DEG C by temperature, are then that the weight of medicinal liquid is endured to adding 1/3rd of water weight by the little fire of 90-100 DEG C by temperature;
C, pure Mel, crystal sugar and mature vinegar endured under slow fire to white sugar and crystal sugar and melt as syrup completely;
D, the syrup obtained in the step c of appropriate part joined in medicinal liquid that step b obtains, by syrup and medicinal liquid mix homogeneously, then be that to be endured by the mixture of the syrup after mix homogeneously and medicinal liquid to relative density be 1.40-1.45 that namely paste obtains cough syrup for the little fire of 90-100 DEG C by temperature.
Radix Ginseng (Classification system PanaxginsengC.A.Mey) sweet in the mouth, micro-hardship, warm in nature, flat, strongly invigorating primordial QI, multiple arteries and veins takes off admittedly, and invigorating the spleen to benefit the lung, promotes the production of body fluid and nourish blood, Fructus Alpiniae Oxyphyllae of calming the nerves.For weak body and prostration, cold extremities faint pulse, insufficiency of the spleen lack of appetite, the deficiency of the lung is breathed with cough, and Tianjin wound is thirsty, and interior-heat is quenched one's thirst, deficiency of qi and blood, and prolonged illness void is won, palpitation with fear insomnia, sexual impotence cold womb.
Rhizoma Polygonati Odorati (Classification system PoLYGoNATIoDoRATIRHIZoMA) is sweet, is slightly cold, can nourishing YIN to relieve dryness, promoting the production of body fluid to quench thirst, and for lung stomach-Yin wound, cough caused by dryness-heat, dry throat and mouth, interior-heat is quenched one's thirst.
Cordyceps militaris (L.) Link. (Classification system Cordycepsmilitaris) righting QI invigorating, improves immunity and hemopoietic function; Tonifying the lung is relievingd asthma, and improves respiratory system; Blood fat in control agent; There is invigorating the lung and the kidney, improve effect of immunity, memory; Spleen-benefiting mind-tranquilizing, has good therapeutical effect for insomnia and dreamful sleep, neurasthenia.
Semen Ginkgo (Classification system GINKGOSEMEN) is sweet, bitter, puckery, flat; Poisonous, can astringing lung QI for relieving asthma, leukorrhagia stopping reducing urination; Breath with cough for abundant expectoration, leukorrhagia nebulousurine, enuresis frequent micturition.
Rhizoma Zingiberis (Classification system ZINGIBERISRHIZ0MA) is pungent, heat, warming spleen and stomach for dispelling cold, and recuperating depleted YANG is promoted blood circulation, warming the lung to resolve fluid-retention; For coldness and pain in the epigastrium, vomiting is had loose bowels, and cold extremities faint pulse, cold fluid-retention is breathed with cough.
Exocarpium Citri Grandis (Classification system CITRIGRANDISEXOCARPIUM) is pungent, bitter, temperature; Regulating the flow of QI to ease the stomach, drying dampness to eliminate phlegm.For cough with copious phlegm, food stagnation is got sick from drinking too much wine, and vomiting and nausea painful abdominal mass is vexed.
Cortex Cinnamomi (Classification system CINNAMOMICORTEX) is pungent, sweet, hot greatly; Mend fire supporing yang, guiding fire to origin, dispersing cold for relieving pain, promoting the flow of QI-blood by warming the meridian.For sexual impotence cold womb, chills and pain of the waist and kness, suffers from a deficiency of the kidney and breathes heavily, upward floating of YANG in deficiency condition, dizzy conjunctival congestion, trusted subordinate's cold type of pain, and deficiency and coldness is vomited and diarrhoea, and colic of cold type is suffered from abdominal pain, dysmenorrhea amenorrhea.
Radix Glycyrrhizae (Classification system GLYCYRRHIZAERADIXETRHIZOMA) is sweet, flat; Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Herba Houttuyniae (Classification system Houttuyniacordata) acrid in the mouth, cold, heat-clearing and toxic substances removing, detumescence can treat skin ulcer, promoting urination to remove dampness, clearing away heat to cure dysentery, invigorating the stomach and promoting digestion, by the lung abscess, sore swollen toxin, hemorrhoidal hemorrhage, retention of heat in the spleen and stomach etc. of controlling excess-heat, pyretic toxicity, damp, disease heat are trouble.Modern pharmacology experiment shows, this product has the effect such as antibacterial, antiviral, raising immunity of organisms, diuresis.
Semen Armeniacae Amarum (Classification system AmygdalusCommunisVas) is rosaceous plant, comprises the kernel of the kind Renhe almond of apricot.The amygdalin composition contained in Semen Armeniacae Amarum can not only relieving cough and asthma, and also having the great function resisting tumor, is contribute greatly pharmaceutically.
Folium Mori (Latin name MulberryLeaf), be the leaf of moraceae plants Mulberry, in Folium Mori, flavone compound accounts for the 1-3% of Folium Mori dry weight, is the class plant that in plant kingdom, stem and leaf content is higher; Alkaloid is the main active ingredient of Folium Mori; In Folium Mori, content of phytosterol than general plant height 3-4 doubly; In Folium Mori, gamma-glutamic acid content is the highest.
Radix Platycodonis (Latin literary fame Platycodongrandiflorus (Jacq.) A.DC.) lung qi dispersing, sore-throat relieving, eliminates the phlegm, evacuation of pus.For cough with copious phlegm, uncomfortable in chest not smooth, pharyngalgia, hoarseness, lung abscess vomiting pus, skin infection difficulty in discharging of pus.
Fructus Mume (Classification system MUMEFRUCTUS) is sour, puckery, flat; Astringe the lung, astringing intestine to stop diarrhea, promotes the production of body fluid, relieving colic caused by ascaris.For chronic cough of deficiency lung, chronic diarrhea chronic dysentery, deficiency-heat is quenched one's thirst, ascariasis of biliary tract vomiting stomachache.
Poria (Classification system PORIA) is sweet, light, flat; Promoting diuresis to eliminate damp pathogen, spleen invigorating, mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.
Rhizoma Phragmitis (Classification system PHRAGMITISRHIZOMA) is sweet, cold; Clearing away heat-fire, promoting the production of body fluid to quench thirst, relieving restlessness, preventing or arresting vomiting, diuresis.For calentura excessive thirst, cough due to lung-heat, lung abscess vomiting pus, gastric heat is vomitted the sound of vomiting, the puckery pain of pyretic stranguria.
Mel (Classification system Mel) is sweet, flat; Invigorating middle warmer, moisturizes, pain relieving, removing toxic substances; External promoting tissue regeneration and ulcer healing.For the empty pain of gastral cavity abdomen, dryness of the lung dry cough, dryness of the intestine constipation, separates Aconitum poison of drug; External treatment skin infection is not held back, burn due to hot liquid or fire.
Crystal sugar, the traditional Chinese medical science thinks the effect that crystal sugar has lung moistening, cough-relieving, clearing away phlegm and reduces internal heat.Also be medicine liqueur brewing, stew the adjuvant boiling tonic.Crystal sugar has invigorating the spleen and replenishing QI, stomach function regulating lung moistening, relieving cough and resolving phlegm, dispel tiredly to quench one's thirst, heat clearing away the turbid descending, YIN nourishing and the production of body fluid promoting, the function such as hidroschesis removing toxic substances, can be used for the diseases such as treatment deficiency of QI in middle-JIAO, cough due to lung-heat, sputum with blood, deficiency of YIN chronic cough, dryness of the mouth and throat, laryngopharynx swelling and pain, infantile night sweat, acute toothache.
Mature vinegar has dissipating blood stasis, hemostasis, removing toxic substances, the effect of parasite killing.
Cough syrup of the present invention has effect of supplementing QI and nourishing YIN, clearing heat and moistening dryness, expectorant cough suppressant and anti-asthmatic.To having thermal burn and gas are cloudy, impairment of both QI and YIN causes chronic cough and the void that prolonged illness deficiency of both the lung and kidney causes to cough in lung, there is good curative effect.Reusing the flat Radix Ginseng of sweet saltiness, Rhizoma Polygonati Odorati and Cordyceps militaris (L.) Link. in the present invention is monarch drug, in order to tonifying the lung nourishing the lung to arrest cough; Ministerial drug has with Semen Ginkgo, Semen Armeniacae Amarum, Rhizoma Zingiberis, Exocarpium Citri Grandis and Poria principal drug assistance effect that respectful lung of astringing the lung reduces phlegm; Adjuvant drug is with Fructus Mume, Rhizoma Phragmitis, Herba Houttuyniae and crystal sugar, and assistant helps the monarch and his subjects, and it is partially to control the monarch and his subjects, makes the monarch and his subjects meritorious without mistake, strengthens effect, side effect is down to minimum; Make medicine with Radix Platycodonis, Folium Mori and Radix Glycyrrhizae, make drug effect in this end objectives of lung system, and there is the mediation property of medicine, make medicine from entrance to body in comparatively affine submissive.Relieving cough and resolving phlegm of the present invention, acute and chronic tracheitis bronchitis, the pneumonopathy such as emphysema, remove the new and old long-pending expectorant of pulmonary, especially for the old expectorant that the granules such as haze dust cause, throat-protecting, throat is dry itches, and throat is hoarse, acute/chronic pharyngitis, promote lung qi, the cough caused for many reasons has significant curative effect.
Beneficial effect of the present invention is: above Chinese medicine combines by the present invention, play synergism, make the cough syrup of relieving cough and relieving asthma effect, cough syrup of the present invention has relieving cough and relieving asthma, appetite promoting and the spleen strengthening, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass, appetite stimulator, refreshes oneself, refreshment conciliates tired effect; The various cough with asthma, cold-phlegm, damp-phlegm, heat-phlegm, phlegm retention, dry phlegm, pertinacious phlegm and the old expectorant that cause for tracheitis, emphysema etc. have therapeutical effect; Therapeutical effect is had for cold and heat laryngopharynx swelling and pain, twinge and dry to itch etc. caused that catch a cold; Many symptoms of effective treatment common cold initial stage, be particularly useful for the old expectorant that the granules such as haze dust cause, throat-protecting, throat is dry itches, and throat is hoarse, acute/chronic pharyngitis, and promote lung qi, the cough caused for many reasons has significant curative effect.
Detailed description of the invention
For making the object, technical solutions and advantages of the present invention clearly, will be described in detail technical scheme of the present invention below.Obviously, described embodiment is only the present invention's part embodiment, instead of whole embodiments.Based on the embodiment in the present invention, other embodiments all that those of ordinary skill in the art obtain under the prerequisite not making creative work, all belong to the scope that the present invention protects.
The invention provides a kind of syrup, the weight portion of it component comprised and each component is as follows: Radix Ginseng 17-30 part; Rhizoma Polygonati Odorati 10-22 part; Cordyceps militaris (L.) Link. 11-22 part; Semen Ginkgo 5-15 part; Semen Armeniacae Amarum; Rhizoma Zingiberis 10-22 part; Exocarpium Citri Grandis 9-21 part; Cortex Cinnamomi 5-15 part; Radix Glycyrrhizae 5-15 part; Folium Mori 5-15 part; Radix Platycodonis 5-15 part; Fructus Mume 20-30 part; Poria 5-15 part; Rhizoma Phragmitis 5-15 part; Herba Houttuyniae 20-30 part; Pure Mel 200-300 part; Crystal sugar 120-200 part; Mature vinegar 60-100 part; Water 200-300 part.
The preparation method of above-mentioned cough syrup is it is characterized in that: described preparation method comprises the following steps:
A, the Radix Ginseng of part appropriate in formula, Rhizoma Polygonati Odorati, Cordyceps militaris (L.) Link., Semen Ginkgo, Semen Armeniacae Amarum, Rhizoma Zingiberis, Exocarpium Citri Grandis, Cortex Cinnamomi, Radix Glycyrrhizae, Folium Mori, Radix Platycodonis, Fructus Mume, Poria, Rhizoma Phragmitis and Herba Houttuyniae are worn into the coarse powder that particle diameter is 0.3-0.7cm respectively;
B, to grind in the coarse powder that obtains add water and mix to step a, coarse powder and decocting in water are opened by the big fire being greater than 110 DEG C by temperature, are then that the weight of medicinal liquid is endured to adding 1/3rd of water weight by the little fire of 90-100 DEG C by temperature;
C, pure Mel and mature vinegar endured under slow fire to white sugar and crystal sugar and melt as syrup completely;
D, the syrup obtained in the step c of appropriate part joined in medicinal liquid that step b obtains, by syrup and medicinal liquid mix homogeneously, then be that to be endured by the mixture of the syrup after mix homogeneously and medicinal liquid to relative density be 1.40-1.45 that namely paste obtains cough syrup for the little fire of 90-100 DEG C by temperature.
Embodiment 1
A kind of syrup, the weight portion of it component comprised and each component is as follows: Radix Ginseng 22 parts; Rhizoma Polygonati Odorati 16 parts; Cordyceps militaris (L.) Link. 16 parts; Semen Ginkgo 10 parts; Semen Armeniacae Amarum; Rhizoma Zingiberis 16 parts; Exocarpium Citri Grandis 15 parts; Cortex Cinnamomi 10 parts; 10 parts, Radix Glycyrrhizae; 10 parts, Folium Mori; Radix Platycodonis 10 parts; Fructus Mume 25 parts; 10 parts, Poria; Rhizoma Phragmitis 10 parts; Herba Houttuyniae 25 parts; Pure Mel 250 parts; 166 parts, crystal sugar; 83 parts, mature vinegar; 250 parts, water.
The preparation method of above-mentioned cough syrup is:
A, the Radix Ginseng of part appropriate in formula, Rhizoma Polygonati Odorati, Cordyceps militaris (L.) Link., Semen Ginkgo, Semen Armeniacae Amarum, Rhizoma Zingiberis, Exocarpium Citri Grandis, Cortex Cinnamomi, Radix Glycyrrhizae, Folium Mori, Radix Platycodonis, Fructus Mume, Poria, Rhizoma Phragmitis and Herba Houttuyniae are worn into the coarse powder that particle diameter is 0.5cm respectively;
B, to grind in the coarse powder that obtains add water and mix to step a, being that coarse powder and decocting in water are opened by the big fire of 150 DEG C by temperature, is then that the weight of medicinal liquid is endured to adding 1/3rd of water weight by the little fire of 95 DEG C by temperature;
C, pure Mel and mature vinegar endured under slow fire to white sugar and crystal sugar and melt as syrup completely;
D, the syrup obtained in the step c of appropriate part joined in medicinal liquid that step b obtains, by syrup and medicinal liquid mix homogeneously, then be that to be endured by the mixture of the syrup after mix homogeneously and medicinal liquid to relative density be 1.43 that namely paste obtains cough syrup for the little fire of 95 DEG C by temperature.
Embodiment 2
A kind of component of syrup and the weight portion of each component as follows: Radix Ginseng 17 parts; Rhizoma Polygonati Odorati 10 parts; Cordyceps militaris (L.) Link. 11 parts; Semen Ginkgo 5 parts; Semen Armeniacae Amarum; Rhizoma Zingiberis 10 parts; Exocarpium Citri Grandis 9 parts; Cortex Cinnamomi 5 parts; 5 parts, Radix Glycyrrhizae; 5 parts, Folium Mori; Radix Platycodonis 5 parts; Fructus Mume 20 parts; 5 parts, Poria; Rhizoma Phragmitis 5 parts; Herba Houttuyniae 20 parts; Pure Mel 200 parts; 120 parts, crystal sugar; 60 parts, mature vinegar; 200 parts, water.
The preparation method of above-mentioned cough syrup is:
A, the Radix Ginseng of part appropriate in formula, Rhizoma Polygonati Odorati, Cordyceps militaris (L.) Link., Semen Ginkgo, Semen Armeniacae Amarum, Rhizoma Zingiberis, Exocarpium Citri Grandis, Cortex Cinnamomi, Radix Glycyrrhizae, Folium Mori, Radix Platycodonis, Fructus Mume, Poria, Rhizoma Phragmitis and Herba Houttuyniae are worn into the coarse powder that particle diameter is 0.3cm respectively;
B, to grind in the coarse powder that obtains add water and mix to step a, being that coarse powder and decocting in water are opened by the big fire of 110 DEG C by temperature, is then that the weight of medicinal liquid is endured to adding 1/3rd of water weight by the little fire of 90 DEG C by temperature;
C, pure Mel and mature vinegar endured under slow fire to white sugar and crystal sugar and melt as syrup completely;
D, the syrup obtained in the step c of appropriate part joined in medicinal liquid that step b obtains, by syrup and medicinal liquid mix homogeneously, then be that to be endured by the mixture of the syrup after mix homogeneously and medicinal liquid to relative density be 1.40 that namely paste obtains cough syrup for the little fire of 90 DEG C by temperature.
Embodiment 3
A kind of component of syrup and the weight portion of each component as follows: Radix Ginseng 30 parts; Rhizoma Polygonati Odorati 22 parts; Cordyceps militaris (L.) Link. 22 parts; Semen Ginkgo 15 parts; Semen Armeniacae Amarum; Rhizoma Zingiberis 22 parts; Exocarpium Citri Grandis 21 parts; Cortex Cinnamomi 15 parts; 15 parts, Radix Glycyrrhizae; 15 parts, Folium Mori; Radix Platycodonis 15 parts; Fructus Mume 30 parts; 15 parts, Poria; Rhizoma Phragmitis 15 parts; Herba Houttuyniae 30 parts; Pure Mel 300 parts; 200 parts, crystal sugar; 100 parts, mature vinegar; 300 parts, water.
The preparation method of above-mentioned cough syrup is:
A, the Radix Ginseng of part appropriate in formula, Rhizoma Polygonati Odorati, Cordyceps militaris (L.) Link., Semen Ginkgo, Semen Armeniacae Amarum, Rhizoma Zingiberis, Exocarpium Citri Grandis, Cortex Cinnamomi, Radix Glycyrrhizae, Folium Mori, Radix Platycodonis, Fructus Mume, Poria, Rhizoma Phragmitis and Herba Houttuyniae are worn into the coarse powder that particle diameter is 0.7cm respectively;
B, to grind in the coarse powder that obtains add water and mix to step a, being that coarse powder and decocting in water are opened by the big fire of 200 DEG C by temperature, is then that the weight of medicinal liquid is endured to adding 1/3rd of water weight by the little fire of 90 DEG C by temperature;
C, pure Mel and mature vinegar endured under slow fire to white sugar and crystal sugar and melt as syrup completely;
D, the syrup obtained in the step c of appropriate part joined in medicinal liquid that step b obtains, by syrup and medicinal liquid mix homogeneously, then be that to be endured by the mixture of the syrup after mix homogeneously and medicinal liquid to relative density be 1.45 that namely paste obtains cough syrup for the little fire of 100 DEG C by temperature.
Cough syrup diabetics of the present invention and anemia of pregnant woman prohibit clothes.
The clinical practice of the cough syrup in embodiment 3:
Clinical data: year April in April, 2013 to 2014, chooses 2000 routine outpatient services altogether and inpatient is treatment target.Wherein female 1000 example, man 1000 example, age reckling 3 years old, the maximum 85 years old, average 37 years old; The shortest person l days of the course of disease, most elder 40 years, because of excessive asthma 432, emphysema 679, seasonal cough 211, upper respiratory tract infection 563 example, bronchiectasis 10 example, other 105 example.2000 routine patients, all to cough, to cough up phlegm, according to medical history, sign, laboratory and x-ray inspection, meet the diagnostic criteria of the relevant cough that State Administration of Traditional Chinese Medicine promulgates, 2000 examples are divided at random treatment group and each 1000 examples of matched group, observe its curative effect.
2, Therapeutic Method: the oral cough syrup l0ml of the present invention for the treatment of group, 3 times/day 7-10 days is 1 course for the treatment of.L0ml is oral for matched group oral administered compound licorice mixture, 3 times/day, within 7-10 days, is 1 course for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome: criterion of therapeutical effect is worked out with reference to State Administration of Traditional Chinese Medicine's " Chinese medical disease Standardization of diagnosis and curative effect ".Cough, transference cure of coughing up phlegm, auscultation of lung and chest X-ray are normally effective; Cough, symptom of coughing up phlegm alleviates, and corresponding sign is improved as improvement; Cough symptom and sign invalid without obviously changing into.Therapeutic outcome: two groups of patients after curative treatment all have clear improvement, effective 447 examples for the treatment of group, effective 523 examples, invalid 10 examples are effectively always 99%, effective 50 examples of matched group, and effective 582 examples, invalid 368 examples, total effective rate is 63.2%.
Be below wherein several typical case:
1) Jilin male's asthmatic patient Zhang of 68 years old, within ill 40 years, once because the excessive asthma a heatable brick bed that crouch does not rise, oral cough syrup of the present invention can descend a heatable brick bed after 10 days, arbitrarily can walk, out go window-shopping after one month;
2) Yancheng shining sun 85 years old and 63 years old two male emphysema patient, ill difference 20 years and 10 years, oral cough syrup of the present invention was relievingd asthma after 15 days, complete antiasthmatic-antitussive after three months;
3) the 35 years old female patient in ground such as Yinchuan, Gansu, Zhangye, Xinjiang, intractable cough for many years, seek medical advice uncontrollable by many places, oral cough syrup of the present invention relieving cough and relieving asthma after three months;
4) Zhejiang Hangzhou 3 years old child patient, coughs and lowly breathes heavily the several months, use up various treatment means invalid, oral cough syrup of the present invention relieving cough and relieving asthma after 7 days;
5) less than 10 years old child 7 people in the ground such as Nantong, Yangzhou, infuses several weeks in hospital once changing according to the season to the autumn and winter, recurrent exerbation, the cough-relieving completely afterwards in 7 days of oral cough syrup of the present invention.
Pharmacological action: 1, Antitussive and Expectorant Effect: after oral to anesthetized dog, can make respiratory mucus secretory volume significantly increase, and sputum is diluted and is easy to discharge.Obvious antitussive effect is had to rat abdominal cavity administration.2, antibacterial action: experiment in vitro to staphylococcus aureus, beta hemolytic streptococcus, diphtheria corynebacterium, have comparatively high inhibition effect.Also certain inhibitory action is had to escherichia coli, Bacillus typhi.3, humoral immune function effect increased: mice serum IgG content can be made obviously to increase, improves mice serum hemolysin (IgM) level, bring out the breeder reaction of bone-marrow-derived lymphocyte, amplify, regulate the responsing reaction of bone-marrow-derived lymphocyte.
The above; be only the specific embodiment of the present invention, but protection scope of the present invention is not limited thereto, is anyly familiar with those skilled in the art in the technical scope that the present invention discloses; change can be expected easily or replace, all should be encompassed within protection scope of the present invention.Therefore, protection scope of the present invention should described be as the criterion with the protection domain of claim.

Claims (3)

1. a syrup, is characterized in that, the weight portion of it component comprised and each component is as follows: Radix Ginseng 17-30 part; Rhizoma Polygonati Odorati 10-22 part; Cordyceps militaris (L.) Link. 11-22 part; Semen Ginkgo 5-15 part; Semen Armeniacae Amarum 5-15 part; Rhizoma Zingiberis 10-22 part; Exocarpium Citri Grandis 9-21 part; Cortex Cinnamomi 5-15 part; Radix Glycyrrhizae 5-15 part; Folium Mori 5-15 part; Radix Platycodonis 5-15 part; Fructus Mume 20-30 part; Poria 5-15 part; Rhizoma Phragmitis 5-15 part; Herba Houttuyniae 20-30 part; Pure Mel 200-300 part; Crystal sugar 120-200 part; Mature vinegar 60-100 part; Water 200-300 part.
2. syrup according to claim 1, is characterized in that: the weight portion of it component comprised and each component is as follows: Radix Ginseng 22 parts; Rhizoma Polygonati Odorati 16 parts; Cordyceps militaris (L.) Link. 16 parts; Semen Ginkgo 10 parts; 10 parts, Semen Armeniacae Amarum; Rhizoma Zingiberis 16 parts; Exocarpium Citri Grandis 15 parts; Cortex Cinnamomi 10 parts; 10 parts, Radix Glycyrrhizae; 10 parts, Folium Mori; Radix Platycodonis 10 parts; Fructus Mume 25 parts; 10 parts, Poria; Rhizoma Phragmitis 10 parts; Herba Houttuyniae 25 parts; Pure Mel 250 parts; 166 parts, crystal sugar; 83 parts, mature vinegar; 250 parts, water.
3. according to claim 1 or 2, the preparation method of syrup is it is characterized in that: described preparation method comprises the following steps:
A, the Radix Ginseng of appropriate part, Rhizoma Polygonati Odorati, Cordyceps militaris (L.) Link., Semen Ginkgo, Semen Armeniacae Amarum, Rhizoma Zingiberis, Exocarpium Citri Grandis, Cortex Cinnamomi, Radix Glycyrrhizae, Folium Mori, Radix Platycodonis, Fructus Mume, Poria, Rhizoma Phragmitis and Herba Houttuyniae are worn into the coarse powder that particle diameter is 0.3-0.7cm respectively;
B, to grind in the coarse powder that obtains add water and mix to step a, coarse powder and decocting in water are opened by the big fire being greater than 110 DEG C by temperature, are then that the weight of medicinal liquid is endured to adding 1/3rd of water weight by the little fire of 90-100 DEG C by temperature;
C, pure Mel, crystal sugar and mature vinegar endured under slow fire to white sugar and crystal sugar and melt as syrup completely;
D, the syrup obtained in the step c of appropriate part joined in medicinal liquid that step b obtains, by syrup and medicinal liquid mix homogeneously, then be that to be endured by the mixture of the syrup after mix homogeneously and medicinal liquid to relative density be 1.40-1.45 that namely paste obtains cough syrup for the little fire of 90-100 DEG C by temperature.
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CN105998802A (en) * 2016-06-25 2016-10-12 李莹 Traditional Chinese medicine preparation for treating coughs and preparation method of traditional Chinese medicine preparation
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CN109170088A (en) * 2018-08-02 2019-01-11 江西金穗丰糖业有限公司 A kind of syrup and preparation method thereof
CN111466563A (en) * 2020-05-29 2020-07-31 山西振东五和健康科技股份有限公司 Composition for nourishing yin, moistening lung, relieving cough and asthma, functional food and preparation method thereof

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