CN104189610A

CN104189610A - Traditional Chinese medicine composition for treating bronchitis

Info

Publication number: CN104189610A
Application number: CN201410486493.4A
Authority: CN
Inventors: 冯秀丽; 袁其华
Original assignee: Individual
Current assignee: Individual
Priority date: 2014-09-22
Filing date: 2014-09-22
Publication date: 2014-12-10

Abstract

The invention discloses a traditional Chinese medicine composition for treating bronchitis. The traditional Chinese medicine composition comprises the following traditional Chinese medicine raw materials in parts by weight: musk, dwarf lilyturf root, corydalis tuber, groundsel, polygonum cuspidatum, radix isatidis, herba patriniae, platycodon grandiflorum, ephedra, liquorice, dandelion, scutellaria baicalensis, rhizoma phragmitis, rhizoma coptidis, honeysuckle stem, herba andrographitis, mint and safflower. The traditional Chinese medicine composition is delicate in compatibility, and has the efficacies of dispelling wind and cold, ventilating lung and eliminating phlegm, relieving cough and asthma, nourishing yin and clearing away lung heat, as well as moistening lung and tonifying kidney, so that fresh air in a lung is sufficient, lung, spleen and kidney functions are conditioned, the autoimmunity is enhanced, the metabolism in vivo is promoted, and both symptoms and root causes are treated; the traditional Chinese medicine composition can be used for quickly restoring the damaged, affected and inflamed tracheal mucosa, activating the activity of antitryptase and alveolar elastic protease, promoting the mucosal cell regeneration, protecting the tracheal mucosa, enhancing the equalization ability of epithelial cells and ciliated cells, effectively relaxing the smooth muscle, eliminating tracheal and bronchial spasms and achieving the purpose of relieving cough and asthma.

Description

A kind ofly treat bronchitic Chinese medicine composition

Technical field

The present invention relates to the field of Chinese medicines, relate to specifically a kind of bronchitic Chinese medicine composition for the treatment of.

Background technology

Bronchitis refers to the chronic nonspecific inflammation of trachea, bronchial mucosa and surrounding tissue thereof.Take clinically cough for a long time, expectoration or with pant and repeatedly outbreak be feature.Part patient can develop into obstructive emphysema, chronic pulmonary heart disease.

Bronchitis is a kind of commonly encountered diseases, frequently-occurring disease, and the repeated infection that main pathogenesis is virus and antibacterial has formed bronchial chronic nonspecific inflammation.Under mercury dropped, respiratory tract small blood vessel spasm ischemia, defense function, degradation is beneficial to pathogenic; The chronic stimulations such as smog dust, atmosphere pollution also can be fallen ill; Smoking makes bronchospasm, mucosa variation, ciliary movement reduction, the favourable infection of mucus secretion increasing; Irritated factor also has certain relation.

At present, bronochitic is at the western medical treatment of acute attack stage and chronic persistence, be mainly infection control and eliminate the phlegm, antitussive is main; Companion adds and uses spasmolytic suppressing panting calming medicine while panting, and advocates associating use antibiotic.Application antibiotic, select according to the kind of pathogenic bacterium, and effect just can be better.The cultivation inspection of determining bronchitis pathogenic bacterium at least needs 3-5 days just can go out result, acute attack person is toward in the past treating, and result of the test is affected by several factors, in addition the restriction of technical conditions, some pathogenic bacteria still can not be cultivated out at present, so rely on cultivation results, select antibiotic, have certain limitation.And Western medicine is aspect treatment bronchitis, not beneficial long-term by antibacterials and use easily hormone.Because easily cause dysbacteriosis by antibacterials for a long time, the state of an illness is unfavorable for controlling; Though life-time service hormone is obvious for removing bronchospasm effect, hormone has the side effect that reduces immunity, causes dependence.

Therefore, life-time service western medicine bronchitis, can cause patient's health to produce drug resistance and Drug resistance, and easily recurrence more, even makes the state of an illness become increasingly complex, and to patient, brings painful and unnecessary trouble.

Summary of the invention

The problem to be solved in the present invention is for above problem, the bronchitic Chinese medicine composition for the treatment of that a kind of good effect, instant effect is provided and is difficult for developing immunity to drugs.

For addressing the above problem, the technical solution adopted in the present invention is:

Treat a bronchitic Chinese medicine composition, it is characterized in that: described Chinese medicine composition is comprised of the Chinese herb of following weight portion:

Moschus 10-20 part, Radix Ophiopogonis 10-20 part, Rhizoma Corydalis 10-20 part, Herba Senecionis Scandentis 10-20 part, Rhizoma Polygoni Cuspidati 10-20 part, Radix Isatidis 10-20 part, Herba Patriniae 10-20 part, Radix Platycodonis 8-12 part, Herba Ephedrae 8-12 part, Radix Glycyrrhizae 8-12 part, Herba Taraxaci 8-12 part, Radix Scutellariae 8-12 part, Rhizoma Phragmitis 8-12 part, Rhizoma Coptidis 8-12 part, Caulis Lonicerae 10-20 part, Herba Andrographis 8-12 part, Herba Menthae 3-8 part, Flos Carthami 8-12 part.

As a kind of prioritization scheme:

Described Chinese medicine composition is comprised of the Chinese herb of following weight portion:

10 parts, Moschus, 10 parts of Radix Ophiopogonis, 10 parts of Rhizoma Corydalis, 10 parts of Herba Senecionis Scandentiss, 10 parts of Rhizoma Polygoni Cuspidati, 10 parts of Radix Isatidis, 10 parts of Herba Patriniae, 8 parts of Radix Platycodoniss, 8 parts, Herba Ephedrae, 8 parts, Radix Glycyrrhizae, 8 parts of Herba Taraxacis, 8 parts of Radix Scutellariaes, 8 parts of Rhizoma Phragmitiss, 8 parts of Rhizoma Coptidis, 10 parts of Caulis Loniceraes, 8 parts of Herba Andrographis, 3 parts of Herba Menthaes, 8 parts, Flos Carthami.

As a kind of prioritization scheme:

20 parts, Moschus, 20 parts of Radix Ophiopogonis, 20 parts of Rhizoma Corydalis, 20 parts of Herba Senecionis Scandentiss, 20 parts of Rhizoma Polygoni Cuspidati, 20 parts of Radix Isatidis, 20 parts of Herba Patriniae, 12 parts of Radix Platycodoniss, 12 parts, Herba Ephedrae, 12 parts, Radix Glycyrrhizae, 12 parts of Herba Taraxacis, 12 parts of Radix Scutellariaes, 12 parts of Rhizoma Phragmitiss, 12 parts of Rhizoma Coptidis, 20 parts of Caulis Loniceraes, 12 parts of Herba Andrographis, 8 parts of Herba Menthaes, 12 parts, Flos Carthami.

As a kind of prioritization scheme:

15 parts, Moschus, 20 parts of Radix Ophiopogonis, 20 parts of Rhizoma Corydalis, 15 parts of Herba Senecionis Scandentiss, 10 parts of Rhizoma Polygoni Cuspidati, 20 parts of Radix Isatidis, 10 parts of Herba Patriniae, 12 parts of Radix Platycodoniss, 8 parts, Herba Ephedrae, 10 parts, Radix Glycyrrhizae, 8 parts of Herba Taraxacis, 12 parts of Radix Scutellariaes, 12 parts of Rhizoma Phragmitiss, 8 parts of Rhizoma Coptidis, 20 parts of Caulis Loniceraes, 12 parts of Herba Andrographis, 5 parts of Herba Menthaes, 12 parts, Flos Carthami.

As a kind of prioritization scheme:

15 parts, Moschus, 15 parts of Radix Ophiopogonis, 15 parts of Rhizoma Corydalis, 15 parts of Herba Senecionis Scandentiss, 15 parts of Rhizoma Polygoni Cuspidati, 15 parts of Radix Isatidis, 15 parts of Herba Patriniae, 10 parts of Radix Platycodoniss, 10 parts, Herba Ephedrae, 10 parts, Radix Glycyrrhizae, 10 parts of Herba Taraxacis, 10 parts of Radix Scutellariaes, 10 parts of Rhizoma Phragmitiss, 10 parts of Rhizoma Coptidis, 15 parts of Caulis Loniceraes, 10 parts of Herba Andrographis, 5 parts of Herba Menthaes, 10 parts, Flos Carthami.

As a kind of prioritization scheme:

Chinese medicine in described Chinese medicine composition is got 100 grams (being soaked in water half an hour) after mixing by weight, add 800 milliliters, water, first very hot oven decocts to water and seethes with excitement, continue five minutes, after change little fire and decoct half an hour, if during water reduce very fast, can add a small amount of water supplements, decoct after 500 milliliters, elimination medicinal residues, obtain oral administration solution.

Wherein,

Moschus, property is pungent, warm, nontoxic, bitter in the mouth.Enter the heart, spleen, Liver Channel, have the refreshment of having one's ideas straightened out, promoting blood circulation to restore menstrual flow, the function of pain relieving dissipating blood stasis.Cure mainly apoplexy, syncope due to accumulation of phlegm, infantile convulsion, attacked by pestiferous factors unhappiness, trusted subordinate's sudden pain, traumatic injury, swollen ulcer drug.

Radix Ophiopogonis, sweet in the mouth, micro-hardship, cold nature, GUIXIN, lung, stomach warp, have promoting diuresis to eliminate damp pathogen, and spleen invigorating, reduces phlegm, the effect of mind tranquilizing and the heart calming.

Rhizoma Corydalis, pungent, hardship, temperature.Pericardium, liver, spleen, lung.There is promoting blood circulation to remove blood stasis, the effect of promoting the circulation of QI to relieve pain.

Herba Senecionis Scandentis, hardship, cold.Heat clearing away, removing toxic substances, parasite killing, improving eyesight.For various acute inflammatory diseases, lobar pneumonia, tonsillitis, enteritis, anemopyretic cold, conjunctival congestion and swelling pain, dysentery, skin eczema.

Rhizoma Polygoni Cuspidati, micro-hardship, is slightly cold.Return liver, gallbladder, lung meridian.Heat-clearing and toxic substances removing, promoting the function of the gallbladder to alleviate jaundice, expelling wind and removing dampness, dissipating blood stasis analgesic therapy, relieving cough and resolving phlegm.For arthralgia, jaundice due to damp-heat, cough with copious phlegm, burn due to hot liquid or fire, injury from falling down, carbuncle sore tumefacting virus.Rhizoma Polygoni Cuspidati has inhibitory action to various bacteria, virus and leptospira, also has in addition blood pressure lowering, blood sugar lowering, blood fat reducing, protects the liver, cathartic relieving constipation, diuresis, hemostasis, antineoplastic action.

Radix Isatidis, has heat-clearing and toxic substances removing, removing heat from blood sore-throat relieving, bactericidal antiphlogistic, antiviral effect.

Herba Patriniae, has heat-clearing and toxic substances removing, anti-inflammatory analgetic, the flat effect of coughing of damp eliminating.

Radix Platycodonis, Radix Platycodonis bitter in the mouth, pungent, property is flat, enters lung meridian, has lung qi dispersing and eliminates the phlegm, removing pus and relieving carbuncle, relieving cough and relieving asthma, the effect of clearing away heat from the throat and easing the chest.

Herba Ephedrae, the effect with relieving the exterior syndrome by diaphoresis, depressed lung-energy dispersing, inducing diuresis to remove edema, loose carbuncle of yin nature, eliminating mass knot, its effective ingredient is ephedrine, d-pseudo-ephedrine, volatile oil and 2,3,5,6-tetramethylpyazine L-α-terpinenol, these compositions can effectively suppress irritated mediator and discharge, and can be antibacterial, antiviral, relieving cough and expelling phlegm.

Radix Glycyrrhizae, nature and flavor are sweet, flat, enter spleen, stomach, lung meridian, and middle emergency, lung moistening, removing toxic substances, controls weakness of the spleen and stomach, lack of appetite, stomachache loose stool, overstrain heating, consumptive lung disease cough, cardiopalmus, laryngopharynx swelling and pain, peptic ulcer.

Herba Taraxaci, sweet, micro-hardship, cold.There is heat-clearing and toxic substances removing, the effect of dispersing swelling and dissipating binds.Cure mainly: upper respiratory tract infection, eye conjunctivitis, mumps, hyperglycemia, gastritis, dysentery, hepatitis, cholecystitis, acute appendicitis, urinary system infection, pelvic inflammatory disease, pharyngitis, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, urinary tract infection.Herba Taraxaci also has hepatic cholagogic, anti-gastric-ulcer, the effect of diuresis.

Radix Scutellariae, hardship, cold.Return lung, gallbladder, spleen, large intestine, small intestine meridian.Heat clearing and damp drying, eliminating fire and detoxication, hemostasis, blood pressure lowering.For hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood is told nosebleed, carbuncle sore tumefacting virus.Radix Scutellariae has antiinflammatory, antibacterial, antiviral, antipyretic, calm, blood fat reducing, atherosclerosis, protects the liver, function of gallbladder promoting, antioxidation, anticancer effect.

Rhizoma Phragmitis, sweet, cold.Return lung meridian, stomach warp.Clearing away heat and promoting production of body fluid, relieving restlessness, preventing or arresting vomiting, diuresis.Cure mainly: for calentura excessive thirst, gastropyretic vomiting, cough due to lung-heat, lung abscess vomiting pus, the puckery pain of pyretic stranguria.

Rhizoma Coptidis, has the effect of heat clearing and damp drying, eliminating fire and detoxication.

Caulis Lonicerae, sweet, cold.Attach to the lung and stomach meridians.Heat-clearing and toxic substances removing, dispelling wind dredging collateral.For epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle skin infection, rheumatism pyretic arthralgia, redness and swelling of joints burning pain.Antibacterial, antiinflammatory, spasmolytic.

Herba Andrographis, bitter in the mouth, cold in nature.GUIXIN, lung, large intestine, urinary bladder channel.Heat-clearing and toxic substances removing, removing heat from blood, detumescence, dampness.Cure mainly: cold, fever, laryngopharynx swelling and pain, aphtha of the mouth and tongue, pertussis chronic cough, dysentery, the puckery pain of pyretic stranguria, carbuncle skin infection, venom.Herba Andrographis also can hepatic cholagogic, antiinflammatory, antitumor, treatment pneumonia and other respiratory inflammations.

Herba Menthae, acrid in the mouth, cool in nature.Return lung, Liver Channel.Cure mainly: dispelling wind and heat pathogens, the clear sharp head, sore-throat relieving rash, soothing the liver circulation of qi promoting.

Flos Carthami, acrid in the mouth, tepor, GUIXIN, Liver Channel.There is promoting blood circulation to restore menstrual flow, the effect of scattered silt pain relieving.Flos Carthami has the effect of heart tonifying, blood pressure lowering, anticoagulation, resisting fatigue, analgesia, calmness, antiinflammatory.

Chinese medicine composition compatibility of the present invention is precise and penetrating, can expelling wind and cold, lung qi dispersing eliminates the phlegm, relieving cough and asthma, YIN nourishing lung heat clearing, lung moistening kidney tonifying, makes the bottom of heart clearing heat in QI system sufficient, and conditioning lung, spleen, renal function, strengthen autoimmunity, promotes body intracellular metabolic, treating both the principal and secondary aspects of a disease; Can repair fast the activity of tunica mucosa tracheae, activation antitrypsin and the white enzyme of alveolar elasticity of damaged and infection inflammation; promote mucomembranous cell regeneration; protection tunica mucosa tracheae; strengthen the ability of equalization of epithelial cell, ciliated cell; effective diastole smooth muscle; eliminate trachea, bronchospasm, reach antiasthmatic-antitussive object.

In addition, Chinese medicine composition of the present invention has been broken through drug resistance, the hepatorenal damage of long-term taking Western medicine generation and has been produced the drawback of various side effect, the efficacy of a drug directs at disease focus, the damage of reparation respiratory system, the regeneration of activation lung cells, thereby raising lung functions, enhancing immunity, and then reach the object for the treatment of disease.

Manufacture method of the present invention:

After being mixed by weight, above-mentioned Chinese medicine gets 100 grams (being soaked in water half an hour), add 800 milliliters, water, first very hot oven decocts to water and seethes with excitement, continue five minutes, after change little fire and decoct half an hour, if during water reduce very fast, can add a small amount of water supplements, decoct to 500 milliliters, filtering medicinal residues, obtain oral liquid.The preparation method of this Chinese medicine composition is simple, convenient, easily row and cost low, as need, make after tablet, powder, pill or capsule can mix above-mentioned Chinese medicine by weight and be ground into end, make tablet, powder, pill or capsule.Instructions of taking: every day potion, every day three times, bfore meals, within seven days, be a course for the treatment of.

The specific embodiment

Embodiment 1: treat bronchitic Chinese medicine composition, choose 10 parts, Moschus, 10 parts of Radix Ophiopogonis, 10 parts of Rhizoma Corydalis, 10 parts of Herba Senecionis Scandentiss, 10 parts of Rhizoma Polygoni Cuspidati, 10 parts of Radix Isatidis, 10 parts of Herba Patriniae, 8 parts of Radix Platycodoniss, 8 parts, Herba Ephedrae, 8 parts, Radix Glycyrrhizae, 8 parts of Herba Taraxacis, 8 parts of Radix Scutellariaes, 8 parts of Rhizoma Phragmitiss, 8 parts of Rhizoma Coptidis, 10 parts of Caulis Loniceraes, 8 parts of Herba Andrographis, 3 parts of Herba Menthaes, 8 parts, Flos Carthami, after mixing, get 100 grams (being soaked in water half an hour), add 800 milliliters, water, first very hot oven decocts to water and seethes with excitement, continue five minutes, after change little fire and decoct half an hour, if what water reduced during this time is very fast, can add a small amount of water supplements, decoct to 500 milliliters, every day potion, every day three times, each 160 milliliters, bfore meals, it within seven days, is a course for the treatment of.Just can fully recover general two to three courses for the treatment of.

Embodiment 2: treat bronchitic Chinese medicine composition, choose 20 parts, Moschus, 20 parts of Radix Ophiopogonis, 20 parts of Rhizoma Corydalis, 20 parts of Herba Senecionis Scandentiss, 20 parts of Rhizoma Polygoni Cuspidati, 20 parts of Radix Isatidis, 20 parts of Herba Patriniae, 12 parts of Radix Platycodoniss, 12 parts, Herba Ephedrae, 12 parts, Radix Glycyrrhizae, 12 parts of Herba Taraxacis, 12 parts of Radix Scutellariaes, 12 parts of Rhizoma Phragmitiss, 12 parts of Rhizoma Coptidis, 20 parts of Caulis Loniceraes, 12 parts of Herba Andrographis, 8 parts of Herba Menthaes, 12 parts, Flos Carthami, after mixing, get 100 grams (being soaked in water half an hour), add 800 milliliters, water, first very hot oven decocts to water and seethes with excitement, continue five minutes, after change little fire and decoct half an hour, if what water reduced during this time is very fast, can add a small amount of water supplements, decoct to 500 milliliters, every day potion, every day three times, each 160 milliliters, bfore meals, it within seven days, is a course for the treatment of.Just can fully recover general two to three courses for the treatment of.

Embodiment 3: treat bronchitic Chinese medicine composition, choose 15 parts, Moschus, 20 parts of Radix Ophiopogonis, 20 parts of Rhizoma Corydalis, 15 parts of Herba Senecionis Scandentiss, 10 parts of Rhizoma Polygoni Cuspidati, 20 parts of Radix Isatidis, 10 parts of Herba Patriniae, 12 parts of Radix Platycodoniss, 8 parts, Herba Ephedrae, 10 parts, Radix Glycyrrhizae, 8 parts of Herba Taraxacis, 12 parts of Radix Scutellariaes, 12 parts of Rhizoma Phragmitiss, 8 parts of Rhizoma Coptidis, 20 parts of Caulis Loniceraes, 12 parts of Herba Andrographis, 5 parts of Herba Menthaes, 12 parts, Flos Carthami, after mixing, get 100 grams (being soaked in water half an hour), add 800 milliliters, water, first very hot oven decocts to water and seethes with excitement, continue five minutes, after change little fire and decoct half an hour, if what water reduced during this time is very fast, can add a small amount of water supplements, decoct to 500 milliliters, every day potion, every day three times, each 160 milliliters, bfore meals, it within seven days, is a course for the treatment of.Just can fully recover general two to three courses for the treatment of.

Embodiment 4: treat bronchitic Chinese medicine composition, choose 15 parts, Moschus, 15 parts of Radix Ophiopogonis, 15 parts of Rhizoma Corydalis, 15 parts of Herba Senecionis Scandentiss, 15 parts of Rhizoma Polygoni Cuspidati, 15 parts of Radix Isatidis, 15 parts of Herba Patriniae, 10 parts of Radix Platycodoniss, 10 parts, Herba Ephedrae, 10 parts, Radix Glycyrrhizae, 10 parts of Herba Taraxacis, 10 parts of Radix Scutellariaes, 10 parts of Rhizoma Phragmitiss, 10 parts of Rhizoma Coptidis, 15 parts of Caulis Loniceraes, 10 parts of Herba Andrographis, 5 parts of Herba Menthaes, 10 parts, Flos Carthami, after mixing, get 100 grams (being soaked in water half an hour), add 800 milliliters, water, first very hot oven decocts to water and seethes with excitement, continue five minutes, after change little fire and decoct half an hour, if what water reduced during this time is very fast, can add a small amount of water supplements, decoct to 500 milliliters, every day potion, every day three times, each 160 milliliters, bfore meals, it within seven days, is a course for the treatment of.Just can fully recover general two to three courses for the treatment of.

Pharmacological evaluation:

In this embodiment, the dosage of each taste Chinese medicine is moderate, applicable to multiple-age bracket crowd, bronchitis is usually had to good therapeutic effect, also can suitably reduce or increase on this basis the grams of each Chinese medicine, but should follow the doctor's advice.

For the further property of medicine of check medicine of the present invention, choose white mice, by anthropic factor, make white mice be test body, carry out respectively cough-relieving, the experiment of reducing phlegm, to test white mice at every turn and be 50, male and female half and half, divide five groups at random, ten every group.Resulting experimental result data form is as follows:

(1) cough-relieving

By strong aqua ammonia nebulization, evaluate the antitussive action of this medicine.White mice is divided 5 groups, it is normal saline group, positive drug matched group (ZHENKELING 6.2ml/kg), respectively one group of this medicine embodiment 1, embodiment 2, embodiment 3, continuous gastric infusion 3d, after 3d administration 40min, white mice is put in the airtight glass container of 1000ml, with ultrasound atomizer, spray into ammonia 1:7,3s excites white mice cough, with white mice, occur that abdominal muscle shrinks simultaneously, contracting breast, open one's mouth (cough sound have or not all can), be cough standard, record, draws and coughs white mice cough number of times in incubation period and 5min.The results are shown in Table 1.This medicine embodiment 1, embodiment 2 all can make the white mice cough latent period number of times that obviously extends, coughs obviously reduce, and all have statistical significance, and be certain dose-effect relationship with blank group comparing difference, show that this medicine has good antitussive action.

This medicine of table 1 on white mice ammonia draw the impact coughed ( ± s, n=10)

With the comparison of normal saline group: * P<0.05, * * P<0.01

(2) reduce phlegm

By observing this medicine to the white mice impact of phenol red output, evaluate the resolve phlegm effect of this medicine.White mice is divided 5 groups, is respectively this medicine embodiment 1, embodiment 2, embodiment 3, positive drug matched group: ammonium chloride group (10g/kg) and blank group, be disposable gastric infusion, and matched group is given and is waited capacity distilled water.After administration 1h, give respectively the phenol red normal saline solution of mice by intraperitoneal injection 5%, the every 20g body weight of volume injected 0.5ml, after injecting phenol red 30min, white mice is put to death in cervical vertebra dislocation, and separated trachea, inserts syringe, connect to prick and fix, by 5% sodium bicarbonate lavation white mice trachea, bronchus, continuous 4 times, each 0.5ml, collect irrigating solution, with 722 type spectrophotometers, at wavelength 546nm place, measure absorbance, according to standard curve, obtain the phenol red output of every white mice, between organizing, compare.The results are shown in Table 2.This medicine embodiment 1, embodiment 2 and embodiment 3 all can make the phenol red output increase of white mice, all have statistical significance, and be certain dose-effect relationship with blank group comparing difference, illustrate that this medical instrument has good phlegm-dispelling functions.

This medicine of table 2 on the white mice impact of phenol red output ( ± s, n=10)

Group	Phenol red concentration (mg/ml)
		Blank group	1.34±0.21
Embodiment 1	2.79±0.54**
		Embodiment 2	2.65±0.43**
Embodiment 3	2.54±0.46**
		Ammonium chloride (1.0g/kg)	2.96±0.61

With the comparison of blank group: * * P<0.01

Model case:

We have chosen 156 routine bronochitics, adopt the method for Chinese and western medicine Comparison of therapeutic further to verify the therapeutic effect of Chinese medicine composition of the present invention and safety.

156 routine bronochitics are divided into two groups at random.Each 78 examples for the treatment of group and matched group.In treatment group, male 35 examples, female's 43 examples; 15～73 years old age, average (42.8 ± 9.6) year; The course of disease the shortest half a year, the longest 12 years.In matched group, male 36 examples, female's 42 examples; 16～72 years old age, average (41.9 ± 10.5) year; The course of disease the shortest half a year, the longest 11 years.The age of two groups of cases, sex, course of disease there was no significant difference, the equal no statistical significance of its difference (P>0.05), has comparability.

Biological indicator is observed Gender, age, weight, body temperature, heart rate, blood pressure.Diagnostic index: observe the symptoms, the course of disease, severity extent, tongue fur, pulse condition.Health giving quality takes stopgap measures: observe and to change before and after primary symptom (cough, expectorant, breathe heavily) treatment and physical signs of lung changes.Safety takes stopgap measures: observe routine blood test, routine urinalysis, electrocardiogram, liver function, renal function and untoward reaction.

Diagnostic criteria is used internal medicine > > and the clinical research of < < new Chinese medicine to know that principle > > formulates according to < < disease of tcm Standardization of diagnosis and curative effect > >, < <.

The oral medicine of the present invention for the treatment of group is decocted rear oral administration solution, potion on the one, and every dose of 500ml, minute morning, noon and afternoon take for three times.100mg of the oral Cefixime tablets of matched group (1), a twice-daily; 0.1～0.2 milligram of salbutamol, spraying l～2 time, once spraying suction in every 4 hours.Be seven days two groups of patients' the course for the treatment of.Observe the curative effect after three courses for the treatment of.In therapeutic process, forbid other about medicine.

Criterion of therapeutical effect recovery from illness: treat cough, expectorant in two weeks, breathe heavily transference cure; Effective: to treat two weeks interior coughs, expectorant, asthma shapes and take an evident turn for the better; Effective: to treat two weeks interior coughs, expectorant, asthma shapes and all take a favorable turn; Invalid: to treat cough, expectorant in two weeks, breathe heavily and just in time organize high being not improved.Curative effect comparision result statistics after two groups of case treatments is in Table 3.

Table 3

Group	Recovery from illness (%)	Effective (%)	Effectively (%)	Invalid (%)	Total effective rate (%)
						Treatment group	67(85.9)	8(10.2)	2(2.6)	1(1.3)	77(98.7)
Matched group	36(46.2)	21(26.9)	11(14.1)	10(12.8)	68(87.2)

By shown in table 3, treatment group total effective rate 98.7%, 87.2%, two group of comparing difference of matched group total effective rate has statistical significance (P < 0.05).Treatment group total effective rate is apparently higher than matched group.By contrast, obviously find out Chinese medicine preparation treatment determined curative effect of the present invention, safe and reliable, treating both the principal and secondary aspects of a disease, is obviously better than Western medicine.

Some patients were healing case is as follows:

Feng, man, 26 years old, before 7 months, because of sense cough after suffering from cold, cough up phlegm, the sputum foam sample that is white in color.Through hospital diagnosis, be bronchitis, through treatment after symptom be eased, but time have repeatedly.One week cause flu cough with asthma, uncomfortable in chest, cough the sticky expectorant of yellow-white, above-mentioned symptom increases the weight of, and patient feels heating, and the heart is tired, and random thoughts gas is tight, and nasal secretion increases, lip cyanosis.Take the Chinese medicine composition of the present invention phenomenon of coughing after a day and disappear, take again transference cure after a course for the treatment of.Follow up a case by regular visits to three not recurrences.

Zheng, man, 65 years old, suffer from bronchitis 8 years, suffer from cold is that cough with asthma is felt suffocated throughout the year, take dry cough as main, occasionally has a small amount of sticky expectorant, in local hospital, treat, effect is not good enough, take Chinese medicine composition of the present invention after the course for the treatment of symptom substantially disappear, add again ten days, patient body obtains rehabilitation, follows up a case by regular visits to 1 year without recurrence.

Chen, female, 48 years old, recurrent cough had a surplus for 5 years, has the symptoms such as cough, abundant expectoration, asthma, and cough expectorant is few, and evening, cough aggravation, was bronchitis by hospital diagnosis, and Zeng hospital is recurrence again after the treatments such as antiinflammatory take a turn for the better, repeatedly not recovery from illness for the treatment of.Take Chinese medicine composition of the present invention transference cure after two courses for the treatment of, because of worried, add again a course for the treatment of, recovery from illness, follows up a case by regular visits to and has no recurrence.

Huang, female, 62 years old, suffer from bronchitis 6 years, recently, because of cough, cough up phlegm and increase the weight of, the heating of companion's fear of cold, low grade fever,, there is right subclavian respiratory chest pain in aggravation.At local hospital, be diagnosed as bronchitis.Because of in hospitalize poor effect, select to take Chinese medicine composition of the present invention, take cough two days later, fever phenomenon disappearance, through the treatment of two courses for the treatment of, disease is removed certainly again, patient's recovery from illness.Follow up a case by regular visits to and have no recurrence.

Claims

1. treat a bronchitic Chinese medicine composition, it is characterized in that: described Chinese medicine composition is comprised of the Chinese herb of following weight portion:

2. the bronchitic Chinese medicine composition for the treatment of according to claim 1, is characterized in that: described Chinese medicine composition is comprised of the Chinese herb of following weight portion:

3. the bronchitic Chinese medicine composition for the treatment of according to claim 1, is characterized in that: described Chinese medicine composition is comprised of the Chinese herb of following weight portion:

4. the bronchitic Chinese medicine composition for the treatment of according to claim 1, is characterized in that: described Chinese medicine composition is comprised of the Chinese herb of following weight portion:

5. the bronchitic Chinese medicine composition for the treatment of according to claim 1, is characterized in that: described Chinese medicine composition is comprised of the Chinese herb of following weight portion: