Summary of the invention
The problem to be solved in the present invention is for above problem, provides a kind of Chinese medicine composition for the treatment of bronchial asthma, and this traditional Chinese medicine composition for treating bronchial asthma is effective, and cure rate is high, and not easily recurs.
For solving the problem, the technical solution adopted in the present invention is:
Treat a Chinese medicine composition for bronchial asthma, it is characterized in that, described Chinese medicine composition is made up of the Chinese herb of following weight portion:
Herba Ephedrae 20-30 gram, Semen Armeniacae Amarum 20-30 gram, Folium Pyrrosiae 10-20 gram, Fructus Gleditsia 10-20 gram, Fructus Toosendan 10-20 gram, Radix Glycyrrhizae Preparata 10-20 gram, Flos Inulae 10-20 gram, Mus bring up careless 10-20 gram, Cornu Cervi tablet 5-10 gram, Cortex Magnoliae Officinalis 5-10 gram, Periostracum Cicadae 5-10 gram, Radix Aucklandiae 5-10 gram.
As a kind of prioritization scheme:
Described Chinese medicine composition is made up of the Chinese herb of following weight portion:
25 grams, Herba Ephedrae, 20 grams, Semen Armeniacae Amarum, Folium Pyrrosiae 15 grams, 20 grams, Fructus Gleditsia, Fructus Toosendan 10 grams, Radix Glycyrrhizae Preparata 15 grams, Flos Inulae 15 grams, Mus bring up grass 20 grams, Cornu Cervi tablet 5 grams, Cortex Magnoliae Officinalis 5 grams, Periostracum Cicadae 10 grams, the Radix Aucklandiae 5 grams.
As a kind of prioritization scheme:
Described Chinese medicine composition is made up of the Chinese herb of following weight portion:
30 grams, Herba Ephedrae, 20 grams, Semen Armeniacae Amarum, Folium Pyrrosiae 10 grams, 15 grams, Fructus Gleditsia, Fructus Toosendan 15 grams, Radix Glycyrrhizae Preparata 10 grams, Flos Inulae 20 grams, Mus bring up grass 15 grams, Cornu Cervi tablet 10 grams, Cortex Magnoliae Officinalis 5 grams, Periostracum Cicadae 5 grams, the Radix Aucklandiae 10 grams.
As a kind of prioritization scheme:
Described Chinese medicine composition is made up of the Chinese herb of following weight portion:
30 grams, Herba Ephedrae, 25 grams, Semen Armeniacae Amarum, Folium Pyrrosiae 20 grams, 10 grams, Fructus Gleditsia, Fructus Toosendan 15 grams, Radix Glycyrrhizae Preparata 10 grams, Flos Inulae 10 grams, Mus bring up grass 15 grams, Cornu Cervi tablet 10 grams, Cortex Magnoliae Officinalis 5 grams, Periostracum Cicadae 5 grams, the Radix Aucklandiae 10 grams.
As a kind of prioritization scheme:
Described Chinese medicine composition is made up of the Chinese herb of following weight portion:
20 grams, Herba Ephedrae, 30 grams, Semen Armeniacae Amarum, Folium Pyrrosiae 15 grams, 15 grams, Fructus Gleditsia, Fructus Toosendan 15 grams, Radix Glycyrrhizae Preparata 10 grams, Flos Inulae 20 grams, Mus bring up grass 15 grams, Cornu Cervi tablet 10 grams, Cortex Magnoliae Officinalis 5 grams, Periostracum Cicadae 10 grams, the Radix Aucklandiae 10 grams.
Wherein:
Wind-cold-dispersing medicinal is called in Herba Ephedrae Chinese medicine, its alkaloid enriches, Chinese medicine important simply, there is antitussive, remove expectorant, diaphoresis, cold expelling, lung qi dispersing, relieving asthma, diuretic, the effect such as detumescence, be mainly used to treatment anemofrigid cold, uncomfortable in chestly breath with cough, the disease such as edema due to wind pathogen edema, bronchial asthma, nourishing the lung to arrest cough, asthma and cough.Ephedrine in water decoction has the effect of adrenomimetic drug sample, and it is by release mediator (indirect action), and direct exciting α and B-adrenergic receptor, and lax bronchial smooth muscle, excited heart, can in order to treat bronchial asthma.
The nutritional labeling such as Semen Armeniacae Amarum rich in proteins, fat, saccharide, carotene, vitamin B group, vitamin C, Citrin and calcium, phosphorus, ferrum, Semen Armeniacae Amarum is called anticancer fruit.Semen Armeniacae Amarum contains abundant fatty oil, has the effect reducing cholesterol, has good effect to control cardiovascular system diseases; Chinese medicine theory is thought, Semen Armeniacae Amarum has effect of promoting the production of body fluid to quench thirst, lung moistening Dingchuan, loosening bowel to relieve constipation, the health care of the patient such as be usually used in the dryness of the lung, breath with cough and treatment, but Semen Armeniacae Amarum is poisonous, only be suitable for the trouble of the excess syndrome such as ailment said due to cold or exposure, dryness of the intestine, when treating the diseases such as pulmonary tuberculosis, bronchitis, chronic enteritis, dry cough without phlegm, single medicinal material can not be taken for a long time.
Folium Pyrrosiae has diuretic, antitussive, eliminates the phlegm, relievings asthma, treating stranguria, lung heat clearing, expel the heat-evil, the effect such as YIN nourishing, be mainly used to the diseases such as treatment cough due to lung-heat, chronic tracheitis, pouring pain, hematuria, lithangiuria, nephritis, metrorrhagia, dysentery, incised wound, carbuncle.Multiplexly clinically treat bronchial asthma, the bronchial asthma of recurrent, chronic bronchitis, chronic nephritis, acute nephritis and pyelonephritis etc.
Fructus Gleditsia be used as medicine can eliminate the phlegm, invigorate blood circulation, dredging collateral, diuresis, have one's ideas straightened out, control tinea, relieving constipation is secret, has antiinflammatory, antiulcer, disease-resistant change effect.Can be used to that treatment locked mouth is not opened, expectorant heaps soil or fertilizer over and around the roots in larynx, bronchial asthma, soldier's so stupor, constipation, lymphoid tuberculosis, apoplexy gnathospasma, expectorant of breathing with cough heap soil or fertilizer over and around the roots, epilepsy, external treatment carbuncle pyogenic infections from tumour or sore.
Fructus Toosendan bitter in the mouth, cold in nature, poisonous, return liver, small intestinal, urinary bladder channel, there is effect of soothing liver-QI, circulation of qi promoting, pain relieving, anthelmintic, the kidney invigorating spasmolytic.
Radix Glycyrrhizae Preparata is the Radix Glycyrrhizae of smoking with honey, Radix Glycyrrhizae Preparata contains the number of chemical compositions such as glycyrrhizin, enoxolone, Angelica Polysaccharide, primary efficacy is with middle emergency, nourishing YIN, enrich blood, negative and positive and adjust, lung moistening, removing toxic substances, coordinating the actions of various ingredients in a prescription, the medical value of Radix Glycyrrhizae has: licoflavone, Radix Glycyrrhizae extractum and enoxolone all have obvious antitussive effect; Phlegm-dispelling functions is also more remarkable; There is the effect of similar adrenocortical hormone sample, have inhibitory action to the gastroxia that histamine causes, and have antiacid and alleviate the effect of gastrointestinal smooth muscle spasm; Radix Glycyrrhizae also has antiinflammatory, anti-allergic effects, can protect throat and the tunica mucosa tracheae of inflammation.
Flos Inulae bitter in the mouth, salty, warm in nature, return lung, stomach, large intestine channel.There is sending down the abnormal ascending QI, expectorant, Hang Shui, preventing or arresting vomiting, relieving asthma, antitussive, the effect such as antibacterial, be mainly used in treating and store the symptoms such as knot, chest and diaphragm feeling of fullness, dyspnea and cough with excessive sputum, vomiting eructation, epigastric oppression and rigidity in cough due to wind and cold, phlegm retention.
Gnaphalium affine D. Don. is commonly called as AnaphalisflauescensHand.-Mazz, be used as medicine for antitussive, eliminate the phlegm, cough with copious phlegm, asthma and bronchitis and non-infectious ulcer, wound ordinary medication, property is gentle, has to reduce phlegm, cough-relieving, blood pressure lowering, cold-dispelling, rush down the effects such as the capable water of expectorant.
The effects such as Cornu Cervi tablet has kidney-replenishing, benefiting essence-blood, tonifying YANG consolidate, bone and muscle strengthening, promoting the circulation of blood detumescence.
Cortex Magnoliae Officinalis acrid in the mouth, warm in nature, return spleen, stomach, large intestine channel, have circulation of qi promoting removing dampness, warming middle-JIAO to relieve pain, dampness, except effects such as full, lowering the adverse QI to relieve asthmas, cure mainly that expectorant stops up QI rising in reverse order, cough due to fluid-retention, insufficiency of stomach is had loose bowels, fullness in the chest is breathed with cough, stagnation of QI due to dyspepsia, abdominal distention constipation, retention of dampness in middle-JIAO, gastral cavity painful abdominal mass vomiting and diarrhoea etc.
The effects such as Periostracum Cicadae has dispelling wind-heat, rash sore-throat relieving, removing nebula to improve visual acuity, expelling wind and relieving convulsion, cure mainly cough hoarseness, lung qi dyspnea with rapid and short breath, cough, anemopyretic cold, laryngopharynx swelling and pain, single board computer rash not thoroughly, the tic of rubella pruritus, cataract, infantile convulsion, the symptom such as tetanus.
Radix Aucklandiae acrid in the mouth, hardship, warm in nature, return spleen, lung, liver, large intestine, tri-jiao channel.The effect such as have circulation of qi promoting, pain relieving, spleen invigorating, help digestion, for stopping up the treatment of the disease such as the cough and asthma of lung, the abdominal distention uncomfortable in chest of turbid damp obstructing in middle-JIAO except stagnant gas in lung, phlegm-damp.Have trachea and the bronchial pharmacological action causing convulsion, cause bronchoconstriction.
Between every taste Chinese medicine in the present invention, by drawing after several clinical formulation, its manufacture method is simple, can be made into the dosage forms such as tablet, pill, powder or oral liquid as required.
Medicine of the present invention has depressed lung-energy dispersing, relieving cough and resolving phlegm, promoting blood circulation to remove obstruction in the collateral, rush down the capable water of expectorant, the kidney invigorating spasmolytic, tonifying YANG consolidates, ventilation Dingchuan, effect of heat clearing away YIN nourishing, take rear drug main from spleen, stomach is through lung, anxious then can cough-relieving, reduce phlegm, relieving asthma, relieving the primary symptom in a chronic case, change the overall environment of human body, fundamentally solve paroxysmally panting of causing because of bronchial asthma, expectoration, out of breath, breast is vexed, cough, the symptoms such as chest pain, and can invigorating spleen to remove dampness be passed through, warming and recuperating the kidney-YANG effects a permanent cure, make respiratory system, urinary system, nervous system and blood system recover the function of self regulation, and preventing chronic obstructive pulmonary disease, emphysema, pulmonary heart disease, heart failure, the generation of the complication such as respiratory failure, final realization is to the thorough treatment of bronchial asthma.
Manufacture method of the present invention:
After being mixed by weight by above-mentioned Chinese medicine, after decocting with water 45 minutes, filtering medicinal residues, obtain oral liquid.Be ground into end after above-mentioned Chinese medicine can mix by tablet, powder, pill or capsule by weight as made, make tablet, powder, pill or capsule.
Instructions of taking: every day potion, every day three times, bfore meals, within ten days, be a course for the treatment of.
The present invention is according to the pharmacology of above-mentioned Chinese medicine, and clinical trial for several times, to blue or green, in, old Different age group light, in, severe asthma patient all has obvious therapeutic effect.
In order to investigate clinical efficacy and the safety of medicine of the present invention further, we are for all kinds of asthmatic patient, and the cause of disease, symptom, extent etc. not have selected 300 routine patients and carried out clinical trial to Drug therapy curative effect of the present invention.
300 routine bronchial asthma patients are divided into two groups at random, often organize 150 routine bronchial asthma patients, in matched group, male 68 example, women 82 example, 30 ~ 40 years old 20 age example, 4l ~ 50 years old 51 example, 5l ~ 60 year old 48 examples, 61 ~ 70 years old 28 example, more than 70 years old 3 is routine; The course of disease 10 months to 5 years; In treatment group, male 70 example, women 80 example; 30 ~ 40 years old 18 age example, 4l ~ 50 years old 52 example, 51 ~ 60 years old 45 example, 61 ~ 70 years old 29 example, more than 70 years old 6 is routine; The course of disease 12 months ~ 7 years.
Two groups of cases through statistical analysis, have comparability in sex, age, the course of disease etc.All cases are all diagnosed with reference to the diagnostic criteria of " internal medicine " mesobronchus asthma.
Matched group adopts current common Therapeutic Method, doxofylline sheet 300mg for oral use, and every day three times, treatment time is 10 days; Treatment group takes the water decoction of medicine of the present invention, potion on the one, and potion divides to be taken for three times, and treatment time is 10 days.
Criterion of therapeutical effect:
Cure---symptoms such as coughing, pant, be uncomfortable in chest and pulmonary's heavy breathing toot sound disappear:
Effective---sign is normal, occasionally has cough, pants and pulmonary's heavy breathing toot sound;
Effectively---symptoms such as coughing, pant, be uncomfortable in chest alleviates to some extent, and the number of times of outbreak reduces to some extent;
Invalid---pant, the symptom such as uncomfortable in chest, out of breath, cough still exists;
Table one
Group |
Number of cases |
Cure n (%) |
Effective n (%) |
Effective n (%) |
Invalid n (%) |
Total effective rate n (%) |
Matched group |
150 |
60(40.0) |
120(80.0) |
130(86.7) |
20(13.3) |
130(86.7) |
Treatment group |
150 |
138(92.0) |
145(96.7) |
148(98.7) |
2(1.33) |
148(98.7) |
By the data contrast in above-mentioned table one, can find out that the cure rate of medicine of the present invention is high, therapeutic effect is remarkable, with take compared with Western medicine, not only total effective rate is better than Western medicine, and treating both the principal and secondary aspects of a disease, fundamentally can solve bronchial asthma, and good stability not easily recurs.
Embodiment 4: a kind of Chinese medicine composition for the treatment of bronchial asthma, described medicine brings up grass 15 grams by 20 grams, Herba Ephedrae, 30 grams, Semen Armeniacae Amarum, Folium Pyrrosiae 15 grams, 15 grams, Fructus Gleditsia, Fructus Toosendan 15 grams, Radix Glycyrrhizae Preparata 10 grams, Flos Inulae 20 grams, Mus, Cornu Cervi tablet 10 grams, Cortex Magnoliae Officinalis 5 grams, Periostracum Cicadae 10 grams, the Radix Aucklandiae 10 grams form.
After above-mentioned Chinese herb mixing, decoct with water half an hour, elimination medicinal residues, just water decoction for oral use, every day potion, every natural gift are taken for three times, bfore meals, it within ten days, is a course for the treatment of, two to three courses for the treatment of just can fully recover, and certainly can carry out suitable interpolation or minimizing according to symptom or age to dose, and follow the doctor's advice, taking period avoids pungent, avoids and flares up.
Some patients healing case is as follows:
Week XX, female, 55 years old, suffer from bronchial asthma existing two more than ten years, midnight can unprovokedly be suppressed awake, just breathes heavily and does not come, accept anti-inflammatory treatment always after meeting wind or penetrating odor, can drug withdrawal just recur, never remove root, after taking the present invention, a course for the treatment of, symptom alleviates to some extent, after continuing to take two courses for the treatment of, diet, daily life recover normal.
Zheng XX, man, 45 years old, the bronchial asthma that before 5 years, heavy cold causes, took treatment with western always, the state of an illness has alleviation, can cough, pant, symptom uncomfortable in chest again and again do not take a turn for the better always, after taking a course for the treatment of of medicine of the present invention, symptom disappears substantially, fully recovers after continuing to take a course for the treatment of.
Liu XX, man, 17 years old, just suffers from allergic rhinitis for one-year-old, find bronchial asthma, the medicine taken antiallergic always He relieving asthma when 8 years old, again and again do not have rehabilitation always, pant, symptom uncomfortable in chest not only do not take a turn for the better and increase the weight of on the contrary, after taking a course for the treatment of of medicine of the present invention, the symptom such as to pant, uncomfortable in chest is clearly better, and the number of occurrence also reduces, fully recover after continuing to take two courses for the treatment of, do not recur so far.
Horse XX, female, 63 years old, postinfectious cough, expectoration, asthma, heating during one's late 30s, have an intravenous drip in clinic a week, other symptom was all fully recovered, and pants and does not still feel any better for more than 20 day, arrive county hospital inspection subsequently and be diagnosed as bronchial asthma.After this between decades, toss about in bed Yu Duojia hospital, seek the good recipe of effecting a radical cure asthma, when being all treatment, symptom is obviously improved at every turn always, surpass after treatment and only within two months, can recur again, and also adhering to taking medicine at ordinary times, or control is not fine, after taking medicine of the present invention after the course for the treatment of, pant, uncomfortable in chest, cough symptom alleviate, diet, daily life recover normal, fully recover after continuing to take two courses for the treatment of, so far without recurrence.