CN102389520B - Chinese medicinal composition for treating chronic bronchitis - Google Patents
Chinese medicinal composition for treating chronic bronchitis Download PDFInfo
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- CN102389520B CN102389520B CN 201110378339 CN201110378339A CN102389520B CN 102389520 B CN102389520 B CN 102389520B CN 201110378339 CN201110378339 CN 201110378339 CN 201110378339 A CN201110378339 A CN 201110378339A CN 102389520 B CN102389520 B CN 102389520B
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Abstract
The invention relates to a medicine for treating bronchitis, particularly a Chinese medicinal composition for treating chronic bronchitis, comprising the following ingredients: 30 weight portions of honeysuckle flower, 20 weight portions of radix scutellariae, 40 weight portions of houttuynia cordata, 10 weight portions of fried almond, 10 weight portions of peach seed, 10 weight portions of fritillary bulb, 20 weight portions of rhizoma polygoni cuspidati, 20 weight portions of hiraute shiny bugleweed herb, 20 weight portions of poria, 6 weight portions of cortex periplocae, 20 weight portions of perillaseed, 20 weight portions of semen raphani, and 10 weight portions of liquorice. The medicine has definite curative effect and no toxic and side effect, and is suitable for treating chronic bronchitis.
Description
Technical field
The present invention relates to a kind of bronchitic medicine for the treatment of, specifically relate to a kind of Chinese medicine composition for the treatment of chronic bronchitis.
Background technology
Chronic bronchitis is one of common disease had a strong impact at present people labour force, annual both at home and abroad have a large amount of patients to merge emphysema, pulmonary heart disease death because suffering from chronic bronchitis, therefore, thoroughly cure chronic bronchitis, be pendulum relevant medical research mechanism and numerous medical personnels one of significant task in front, be also each medical personnel's effort target.Current, chronic bronchitis has the Therapeutic Method of two kinds of medical models in China, is exactly western medical treatment and Chinese traditional treatment, and western medical treatment mainly contains infection control at present, eliminating phlegm and relieving cough, and spasmolytic is relievingd asthma, and controls several measures of complication.But chronic bronchitis is unlike other diseases, and treatment has certain difficult problem, a lot of people live and are accustomed to being difficult to change, for example: smoke, take for a long time antibiotic, the application hormone etc. of relying.Environmental pollution factors also is difficult for solving in addition.Whether many old-slow-bronchial tube patient tobacco habits are difficult to change, and pay no attention to the state of an illness and need, and often use irrelevantly antibacterials and hormone, result to make more and more refractory of the state of an illness, cause aggravation and delay.The chance of bringing out chronic bronchitis time outbreak also exists constantly, and tend to make its progress because of the outbreak repeatedly of pathological changes, and then obstructive emphysema, pulmonary heart disease etc. appear, this has just brought very large injury to the patient, because to the degree of emphysema and pulmonary heart disease occurring, just be difficult to lapse to, still do not treat the effective ways of this complication at present, can only control the repeated infection of chronic bronchitis as far as possible.The Chinese medicine chronic bronchitis, although there have been certain method and experience in many doctors or medical institutions, really can be worth generally promoting and the experiences and achievement of use remains at present and do not have.
Along with scientific and technological progress and development, it is also more and more that people treat this sick method, as: " Immune intervention therapy ", " TDDS targeted activation immunity composite treatment ", " burying interior thin Chinese medicine outward " etc.Make us for the treatment technology of chronic bronchitis, very much progress arranged, yet these researchs also do not make substantial breakthroughs at present, because these treatment meanss are captured and still can't be determined the time of chronic bronchitis.
summary of the invention:
At the bottom of solving above-mentioned cure rate, the problem that uncertain therapeutic efficacy is cut, the invention provides a kind of Chinese medicine composition that can treat chronic bronchitis.
Technical scheme of the present invention is: a kind of Chinese medicine composition for the treatment of chronic bronchitis, it is characterized in that, and by the crude drug of following weight parts, made: Flos Lonicerae 30, Radix Scutellariae 20, Herba Houttuyniae 40, stir-baked SEMEN ARMENIACAE AMARUM 10, Semen Persicae 10, Bulbus Fritillariae Thunbergii 10, Rhizoma Polygoni Cuspidati 20, the Herba Lycopi 20, Poria 20, periploca sepium 6, Fructus Perillae 20, Semen Raphani 20, Radix Glycyrrhizae 10.
Can adopt following preparation method: take above-mentioned crude drug by above-mentioned weight portion, the ratio that adds 2500 milliliters, water according to every weight portion dose adds water, soaks 1 hour, decocts, and seethes with excitement 50 minutes, and the leaching medicinal liquid, be concentrated to 150ml, standby.Also can adopt other common method preparation.
The Chinese medicine composition of described treatment chronic bronchitis also can be made into tablet, oral liquid, granule, and the dosage forms such as capsule are more easily preserved medicine, and taking convenience.
Using method: get a medical material amount decoction liquor 150ml, be divided into three morning, noon and afternoon to take.It within 10th, is a course for the treatment of.Symptom is alleviation person fully not, and after finishing the course for the treatment of, drug withdrawal is 1～2, then takes continuously 2～3 courses for the treatment of, to transference cure, then carries out the treatment of 1 above course for the treatment of, with the after treatment effect.
Effect and mechanism:
Flos Lonicerae: sweet, cold.Return lung, the stomach warp.The effect heat-clearing and toxic substances removing, wind-heat dissipating.
Radix Scutellariae: hardship, cold.Return lung, gallbladder, spleen, stomach, large intestine, small intestine meridian.The effect heat clearing and damp drying, eliminating fire and detoxication.
Herba Houttuyniae: suffering is slightly cold.Return lung meridian.The effect heat-clearing and toxic substances removing, the eliminating carbuncle evacuation of pus.
Stir-baked SEMEN ARMENIACAE AMARUM: hardship, suffering, micro-sweet, temperature.Enter lung, large intestine channel.The effect expelling phlegm for arresting cough, relieving asthma.
Semen Persicae: hardship, sweet, flat.Enter lung, liver, large intestine channel.Effect blood stasis dispelling blood and antitussive.
Bulbus Fritillariae Thunbergii: hardship, cold.Return lung, heart channel.The effect removing heat-phlegm, sending down the abnormal ascending QI cough-relieving, lung moistening, eliminating stagnation eliminating carbuncle.
Rhizoma Polygoni Cuspidati: hardship, cold.Return liver, gallbladder, lung meridian.The effect expelling wind and removing dampness, dissipating blood stasis analgesic therapy, relieving cough and resolving phlegm.
Herba Lycopi: hardship, tepor.Enter liver, urinary bladder channel.The effect removing stasis to stop bleeding, supplementing QI to induce diuresis.
Poria: sweet, light, flat.Return liver, the stomach warp.Effect is eliminated edema distension, phlegm retention cough with dyspnea.
Periploca sepium: suffering, hardship, temperature.GUIXIN, kidney channel.The diuresis of effect heart tonifying, invigorating the liver and kidney.
Fructus Perillae: acrid in the mouth, temperature.Return lung meridian.The expectorant of effect sending down the abnormal ascending QI, relieving asthma.
Semen Raphani: suffering, sweet, flat.Return lung, spleen, stomach warp.Effect is told wind-phlegm, and dispersing wind and cold is determined the phlegm dyspnea cough.
Radix Glycyrrhizae: sweet, flat.Enter spleen, lung meridian, effect and in, emergency, pain relieving, eliminate the phlegm, the removing toxic substances.
Above all medicines share, and can play lung moistening, the eliminating stagnation eliminating carbuncle, and heat-clearing and toxic substances removing, relieving cough and resolving phlegm, lowering the adverse-rising QI to subdue asthma, supplementing QI to induce diuresis, the dissipating blood stasis analgesic therapy, eliminate the edema distension, the effect of heart tonifying diuresis.So can play good therapeutical effect to chronic bronchitis and even its complication.
The scope of application: evident in efficacy to chronic bronchitis, the treatment that bronchitis and chronic bronchitis is merged to emphysema, pulmonary heart disease also has effect preferably.
By the observation to a large amount of chronic bronchitis patients and analysis; we find the generation of chronic bronchitis; mostly relevant with infection; bronchitis from the beginning of how because of due to respiratory virus infection; these Virus entry bronchus ciliated epithelial cells at interior amount reproduction; destroy mucosa and epithelial cell, make it lose protective effect.Secondly be physics, chemical irritation: long-term smoking and air are polluted by chemical toxicant, dust or harmful industrial waste gas, and respiratory mucosa is had to stimulation, have damaged the normal cleaning of mucosa and defense function.In addition, cold, irritated factor, immunity degradation are also the major incentive that causes the chronic bronchitis outbreak.Chronic bronchitis shows effect repeatedly, bronchial lumen is exhaled and be obstructed, and then just forms obstructive emphysema and even pulmonary heart disease, has a strong impact on patient's work capacity and healthy.Of a specified duration heat, expectorant, the wet syndrome of just can causing, form the weakened body resistance complex situations of the domination of pathogen.Occur that cough is out of breath, very dyspnea, cough up and tell the sticky expectorant of the clear rare foam of white, lossless aversion to cold, physical distress and heavy, limbs edema very, white and slippery fur, the syndromes such as stringy and tense pulse.So, in the treatment of chronic bronchitis, should pay attention to heat-clearing and toxic substances removing, relieving cough and resolving phlegm, lowering the adverse-rising QI to subdue asthma, supplementing QI to induce diuresis, the dissipating blood stasis analgesic therapy, eliminate the edema distension, heart tonifying diuresis etc.Disease progression can be effectively controlled, and the effect of final healing can be reached.This formula righting and the use simultaneously of getting rid of evils, directly the cause of disease is eliminated together with the indirect cause of disease, so successful is a kind of effective Chinese medicine composition be worth of widely use.
The invention has the beneficial effects as follows: this Chinese medicine composition both can be used separately the treatment chronic bronchitis, also can treat with western medicine and medical practitioners, the treatment measures such as " Immune intervention therapy ", " TDDS targeted activation immunity composite treatment ", " burying interior thin Chinese medicine outward " are used simultaneously, be characterized in that instant effect, curative effect are reliable, have no side effect.Both the state of an illness of chronic windpipeitis infection can be alleviated in a short time, complication can be controlled again.Can also significantly strengthen human body constitution simultaneously, improve himself disease-resistant repair ability.Be a kind ofly than treatment measures such as western medicine and medical practitioners, " Immune intervention therapy ", " TDDS targeted activation immunity composite treatment ", " burying interior thin Chinese medicine outward ", more to produce effect, and the anti-chronic bronchial of the ideal of being free from side effects infect and the medicine of cough with asthma.
The specific embodiment
Crude drug weight portion formula: Flos Lonicerae 30, Radix Scutellariae 20, Herba Houttuyniae 40, stir-baked SEMEN ARMENIACAE AMARUM 10, Semen Persicae 10, Bulbus Fritillariae Thunbergii 10, Rhizoma Polygoni Cuspidati 20, the Herba Lycopi 20, Poria 20, periploca sepium 6, Fructus Perillae 20, Semen Raphani 20, Radix Glycyrrhizae 10.
Preparation method: take above-mentioned crude drug by above-mentioned weight portion, the ratio that adds 2500 milliliters, water according to every weight portion dose adds water, soaks 1 hour, decocts, and seethes with excitement 50 minutes, and the leaching medicinal liquid, be concentrated to 150ml, standby.
Using method: getting a crude drug amount decoction liquor, be divided into three morning, noon and afternoon respectively to take 50ml, 10th is a course for the treatment of.
Below in conjunction with clinical data and model case, the present invention is further illustrated:
One, clinical observation
1. clinical data: be selected from outpatient's totally 146 examples that there is complete chronic bronchitis example data year October in June, 2009 to 2011.Be divided at random treatment by Chinese herbs group 73 examples, male 61 examples wherein, female's 12 examples, age 56-78 year.Matched group 73 examples, male 62 examples wherein, female's 11 examples, age 55-78 year, two groups of sexes, age ratios there are no significant difference (p>0.05).
2. diagnostic criteria: its diagnostic criteria with reference in " disease of tcm Standardization of diagnosis and curative effect " about the diagnostic criteria of chronic bronchitis.
3. Therapeutic Method: treatment group is taken medicine of the present invention, and 150 milliliters of every days, minute three morning, noon and afternoon take, each 50 milliliters.Within 10th, be a course for the treatment of, discontinue medication between per course for the treatment of 1～2, proceed the treatment of the next course for the treatment of, take continuously 2 courses for the treatment of or longer.
Matched group gives western medicine, and dirty sodium 2 grams of cephalo plug, add 100 milliliters of intravenous drips of 0.9% normal saline, every day 2 times, or levofloxacin 0.4 ~ 0.6 gram, adds 250 milliliters of intravenous drips of 0.9% normal saline, every day 1 time.Aminophylline 0.5 gram, add 100 milliliters of 0.9% normal saline, intravenous drip, and every day 1 time, 60 ~ 90 milligrams of ambroxols, add in 250 ml physiological salines, intravenous drip, every day 1 time.Continuous application repeats in 10 days afterwards.
4. efficacy assessment standard: efficacy assessment standard is formulated with reference to " disease of tcm Standardization of diagnosis and curative effect ".Clinical recovery: cough, expectoration, asthma symptom disappear, and can work and live.Effectively: cough, expectoration, asthma symptom alleviate, and respiratory function improves.Invalid: symptom and sign is without improvement.
5. therapeutic outcome: two groups of therapeutic outcomes are as shown in table 1 and table 2:
Table 1 treatment two groups of cure rate synopsis after 10 days
Through X 2 test, relatively, difference has very significant (P<0.001) to two groups of total effective rates.
Table 2 treatment two groups of cure rate synopsis after 20 days
| Group | Example time | Recovery from illness/example | Significant figure/example | Invalid number/example | Total effective rate (%) |
| Treatment group | 73 | 43 | 30 | 0 | 100 |
| Matched group | 73 | 22 | 39 | 12 | 83.56 |
Through X 2 test, relatively, difference has very significant (P<0.001) to two groups of total effective rates.
In a word, in Comprehensive Treatment, utilize and take Drug therapy chronic bronchitis of the present invention and merge emphysema and patients with cor pulmonale 73 examples, total effective rate is up to 97.26% and 100%, far above 64.86% and 83.56% total effective rate of matched group, and treatment group all has no side effect.
Two, model case is as follows:
Case 1: Liu Yuping, the female, 56 years old, suffer from chronic bronchitis more than 20 years, cough, asthma increases the weight of 10 days, coughs yellow sputum.C-XF shows: thorax is full, two enhanced lung markings, and the lung field transmittance strengthens, and two diaphragms are low flat, and heart is the position of hanging down.Diagnosing chronic bronchitis emphysema sign.After the application of the invention Drug therapy after 10 days symptom obviously alleviate.
Case 2: Niu Yuefen, the female, 60 years old, chronic bronchitis history 18 years, cough, asthma increases the weight of 15 days, coughs yellow sputum 7 days.C-XF shows: chronic bronchitis emphysema, intrapulmonary infection sign.The application of the invention Drug therapy after 10 days symptom obviously alleviate.
Case 3: Wang Lizhong, the man, 65 years old, chronic bronchitis history more than 10 years, cough, asthma increases the weight of 7 days, the heat that occurs together, C-XF shows: chronic bronchitis emphysema sign.The application of the invention Drug therapy is cured in 20 days afterwards substantially.
Case 4: Wang Wanxiu, the man, 72 years old, chronic cough, companion asthma 30 years, increase the weight of to accompany expectoration, breast CT to show chronic bronchitis emphysema, pulmonary heart disease sign in nearly 3 days.Use Drug therapy of the present invention after 20 days symptom substantially disappear.
Case 5: Gu Jinggui, the man, 67 years old, asthma and expectoration, and cardiopalmus, edema of lower limbs, appearred cough in nearly 5 days, in chronic bronchitis history more than 10 years.C-XF is chronic bronchitis emphysema, pulmonary heart disease sign.Use Drug therapy of the present invention after 15 days symptom obviously alleviate.
Case 6: Li Dongsheng, man, 63 years old
,heating, expectoration appears, in chronic cough, companion's asthma 16 years recently.C-XF diagnosis: meet chronic bronchitis emphysema.Take Drug therapy of the present invention sx↓ after 5 days, substantially cure after 2 courses for the treatment of
.
Claims (2)
1. a Chinese medicine composition for the treatment of chronic bronchitis, is characterized in that being made by the following weight parts crude drug: Flos Lonicerae 30, Radix Scutellariae 20, Herba Houttuyniae 40, stir-baked SEMEN ARMENIACAE AMARUM 10, Semen Persicae 10, Bulbus Fritillariae Thunbergii 10, Rhizoma Polygoni Cuspidati 20, the Herba Lycopi 20, Poria 20, periploca sepium 6, Fructus Perillae 20, Semen Raphani 20, Radix Glycyrrhizae 10.
2. the Chinese medicine composition for the treatment of chronic bronchitis according to claim 1, it is characterized in that described Chinese medicine composition adopts following preparation method to make: every weight portion adds 2500 ml waters, soaks 1 hour, decoct, seethe with excitement 50 minutes, filter, be concentrated to 150ml.
3. the Chinese medicine composition for the treatment of chronic bronchitis according to claim 1, the dosage form that it is characterized in that described Chinese medicine composition is decoction, tablet, oral liquid, granule or capsule.
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| Application Number | Priority Date | Filing Date | Title |
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| CN 201110378339 CN102389520B (en) | 2011-11-24 | 2011-11-24 | Chinese medicinal composition for treating chronic bronchitis |
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| CN 201110378339 CN102389520B (en) | 2011-11-24 | 2011-11-24 | Chinese medicinal composition for treating chronic bronchitis |
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| CN102389520B true CN102389520B (en) | 2013-09-11 |
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| CN105381231A (en) * | 2015-10-09 | 2016-03-09 | 薄璐丽 | Traditional Chinese medicine fumigating and washing agent for treating bronchitis of infants and nursing method |
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Non-Patent Citations (4)
| Title |
|---|
| 《中医药治疗老年人肺炎的临床与实验研究》;杨戈;《中医药学刊》;20031231;第21卷(第12期);2034-2037 * |
| 姜良铎.特发性肺间质纤维化的病因论治.《北京中医药》.2008,第27卷(第4期),252-254. |
| 杨戈.《中医药治疗老年人肺炎的临床与实验研究》.《中医药学刊》.2003,第21卷(第12期),2034-2037. |
| 特发性肺间质纤维化的病因论治;姜良铎;《北京中医药》;20080430;第27卷(第4期);252-254 * |
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