CN105250771A - Traditional Chinese medicine oral solution for treating chronic pharyngitis and preparation method of traditional Chinese medicine oral solution - Google Patents

Traditional Chinese medicine oral solution for treating chronic pharyngitis and preparation method of traditional Chinese medicine oral solution Download PDF

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CN105250771A
CN105250771A CN201510755390.8A CN201510755390A CN105250771A CN 105250771 A CN105250771 A CN 105250771A CN 201510755390 A CN201510755390 A CN 201510755390A CN 105250771 A CN105250771 A CN 105250771A
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radix
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陈慧珊
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Abstract

The invention discloses a traditional Chinese medicine oral solution for treating chronic pharyngitis and a preparation method of the traditional Chinese medicine oral solution. The traditional Chinese medicine oral solution is prepared from the following raw materials in parts by weight: 12-18 parts of oroxylum indicum, 12-18 parts of radix scrophulariae, 27-33 parts of rhizoma phragmitis, 12-18 parts of cicada slough, 9-15 parts of Chinese olives, 4-10 parts of mint, 7-13 parts of hen egg membranes, 17-23 parts of lophatherum gracile, 17-23 parts of radix ophiopogonis, 12-18 parts of fructus arctii, 17-23 parts of dendrobium, 17-23 parts of radix glehniae, 12-18 parts of rhizoma anemarrhenae and 4-10 parts of liquorice. The traditional Chinese medicine oral solution has the effects of nourishing yin for lowering fire, strengthening the body resistance to eliminate evils as well as diminishing inflammation and detoxifying and is a traditional Chinese medicine composition which is safe, reliable, free of any toxic or side effects, high in effective component utilization ratio and capable of rapidly taking effects.

Description

A kind of Chinese medicine oral liquid and preparation method for the treatment of chronic pharyngitis
Technical field
The present invention relates to a kind of Chinese medicine oral liquid for the treatment of chronic pharyngitis, belong to the field of Chinese medicines.
Background technology
Chronic simple pharyngitis is also known as chronic pharyngitis, more common, pathological changes is mainly at mucous layer, show as pharyngeal mucosa chronic congestion, infiltration of more lymphocytes is had around its blood vessel, also show leukocyte and plasmocyte infiltrating, connective tissue proliferation under mucosa and mucosa, mucous gland can be loose, secretory function is hyperfunction, mucilage secretion increases, common adult, the course of disease is long, easy recurrence, the cause of disease many because of acute pharyngitis recurrent exerbation or treatment not thorough, and adjacent organs focus stimulates as sinusitis, tonsillitis, nasopharyngitis, tracheitiies etc. cause, tobacco and wine are excessive, dust and harmful gas stimulate for commonly encountered diseases because of, the western medical treatment Main Means taked this disease at present takes antibiotic, but western medicine is temporary transient symptom management mostly, and it is harmful unhelpful to take too many antibiotic.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide a kind of Chinese medicine oral liquid for the treatment of chronic pharyngitis, it has nourishing YIN to lower pathogenic fire, strengthening vital QI to eliminate pathogenic factors, effect of antiinflammatory removing toxic substances.
The present invention is achieved through the following technical solutions:
Treat a Chinese medicine oral liquid for chronic pharyngitis, be made up of following raw material: Semen Oroxyli 12-18 part, Radix Scrophulariae 12-18 part, Rhizoma Phragmitis 27-33 part, Periostracum Cicadae 12-18 part, Fructus Canarii 9-15 part, Herba Menthae 4-10 part, Membrana Follicularis ovi 7-13 part, Herba Lophatheri 17-23 part, Radix Ophiopogonis 17-23 part, Fructus Arctii 12-18 part, Herba Dendrobii 17-23 part, Radix Glehniae 17-23 part, Rhizoma Anemarrhenae 12-18 part, Radix Glycyrrhizae 4-10 part.
Preferably, each parts by weight of raw materials is: Semen Oroxyli 15 parts, Radix Scrophulariae 15 parts, Rhizoma Phragmitis 30 parts, Periostracum Cicadae 15 parts, Fructus Canarii 12 parts, Herba Menthae 7 parts, Membrana Follicularis ovi 10 parts, Herba Lophatheri 20 parts, Radix Ophiopogonis 20 parts, Fructus Arctii 15 parts, Herba Dendrobii 20 parts, Radix Glehniae 20 parts, the Rhizoma Anemarrhenae 15 parts, 7 parts, Radix Glycyrrhizae.
Pharmacological action:
Semen Oroxyli: nature and flavor with return through: bitter, sweet, cool; Return lung, liver, stomach warp, function with cure mainly: removing heat from the lung and relieving sorethroat, dispersing the stagnated liver-QI for regulating the stomach; For cough due to lung-heat, sore throat, hoarseness, stomachache due to hyperactive liver-QI attacking the stomach.
Radix Scrophulariae: nature and flavor with return through: sweet, bitter, salty, be slightly cold; Return lung, stomach, kidney channel, function with cure mainly: removing heat from blood YIN nourishing, eliminating fire and detoxication; For consumption of YIN caused by febrile disease, crimson tongue excessive thirst, maculae caused by violent heat pathogen, constipation is hindered in Tianjin, hectic fever due to YIN-deficiency chronic cough, conjunctival congestion, pharyngalgia, scrofula, diphtheria, carbuncle sore tumefacting virus.
Rhizoma Phragmitis: nature and flavor with return through: sweet, cold; Attach to the lung and stomach meridians, function with cure mainly: clearing away heat and promoting production of body fluid, relieving restlessness, preventing or arresting vomiting, diuresis; For calentura excessive thirst, gastric heat is vomitted the sound of vomiting, cough due to lung-heat, lung abscess vomiting pus, the puckery pain of pyretic stranguria.
Periostracum Cicadae: nature and flavor with return through: sweet, cold; Return lung, Liver Channel, function with cure mainly: loose wind heat extraction, sore-throat relieving, rash, nebula removing, spasmolytic; For anemopyretic cold, pharyngalgia, hoarseness, measles without adequate eruption, rubella pruritus, cataract, convulsion with spasms, tetanus.
Fructus Canarii: nature and flavor with return through: sweet, sour, flat; Attach to the lung and stomach meridians, function with cure mainly: heat clearing away, sore-throat relieving, promotes the production of body fluid, removing toxic substances; For laryngopharynx swelling and pain, cough, excessive thirst, fish Eriocheir sinensis is poisoning.
Herba Menthae: nature and flavor with return through: pungent, cool; Return lung, Liver Channel, function with cure mainly: dispelling wind-heat; Refresh oneself, rash; For anemopyretic cold, pathogenic wind-warm from the beginning of, headache, conjunctival congestion, sore throat, aphtha, rubella, measles, breast the side of body feeling of distension and oppression.
Membrana Follicularis ovi: nature and flavor: sweet in the mouth, light, property is put down, Gui Jing: spleen, stomach, lung meridian, and function cures mainly: nourishing YIN and clearing away lung-heat, sore, removing nebula, synthetism; Asthma is coughed, pharyngalgia aphonia, lymphoid tuberculosis, ulcer being unable to heal, the raw cataracta of order, the vertigo, trauma fracture outside main;
Herba Lophatheri: nature and flavor with return through: sweet, light, cold; GUIXIN, stomach, small intestine meridian, function with cure mainly: clearing heat and relieving fidgetness, diuresis; For calentura excessive thirst, hot urination drenches pain, aphtha of the mouth and tongue.
Radix Ophiopogonis: nature and flavor with return through: sweet, micro-hardship, is slightly cold; GUIXIN, lung, stomach warp, function with cure mainly: YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire; For dryness of the lung dry cough; Chronic consumptive disease is coughed, and Tianjin wound is thirsty, vexed insomnia, and interior-heat is quenched one's thirst, dryness of the intestine constipation; Pharyngeal diphtheria.
Fructus Arctii: nature and flavor with return through: pungent, bitter, cold; Attach to the lung and stomach meridians, function with cure mainly: dispelling wind and heat pathogens, lung qi dispersing rash, resolving toxin and disinhibiting the throat; For anemopyretic cold, cough with copious phlegm, measles, rubella, laryngopharynx swelling and pain, mumps erysipelas, carbuncle sore tumefacting virus.
Herba Dendrobii: nature and flavor with return through: sweet, be slightly cold; Return stomach, kidney channel, function with cure mainly: reinforcing stomach reg fluid, nourishing YIN and clearing away heat; Lose for cloudy impairment of body fluid, xerostomia excessive thirst, lack of appetite is retched, deficiency-heat after being ill, poor vision.
Radix Glehniae: nature and flavor with return through: sweet, micro-hardship, is slightly cold; Attach to the lung and stomach meridians, function with cure mainly: nourishing YIN and clearing away lung-heat, reinforcing stomach reg fluid; For lung-heat type cough, chronic cough expectorant blood, calentura Tianjin wound is thirsty.
The Rhizoma Anemarrhenae: nature and flavor with return through: bitter, sweet, cold; Return lung, stomach, kidney channel, function with cure mainly: clearing away heat-fire, promote the production of body fluid and moisturize; For fever caused by exogenous pathogenic factors, high hot excessive thirst, lung-heat type cough, osteopyrexia and fever, interior-heat is quenched one's thirst, dryness of the intestine constipation.
Radix Glycyrrhizae: nature and flavor with return through: sweet, flat; GUIXIN, lung, spleen, stomach warp, function with cure mainly: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription; For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Another technical problem to be solved by this invention is to provide a kind of preparation method preparing above-mentioned Chinese medicine oral liquid.
Another technical problem to be solved by this invention is achieved through the following technical solutions:
Treat a preparation method for the Chinese medicine oral liquid of chronic pharyngitis, be prepared from by following methods:
(1) raw material Semen Oroxyli, Periostracum Cicadae, Fructus Canarii, Membrana Follicularis ovi, Herba Lophatheri, Radix Ophiopogonis, Fructus Arctii, Herba Dendrobii, Radix Glehniae, the Rhizoma Anemarrhenae, Radix Glycyrrhizae cleaning is got, utilize hot-air seasoning after cleaning, hot blast wind speed is 2-4m/s, and drying time is 1-12h, 10-20 order is ground into after oven dry, for subsequent use;
(2) get raw material Radix Scrophulariae, Rhizoma Phragmitis, Herba Menthae cleaning, utilize hot-air seasoning after cleaning, hot blast wind speed is 2-4m/s, and drying time is 1-12h, is ground into 10-20 order after oven dry, for subsequent use;
(3) Semen Oroxyli after pulverizing in step (1), Periostracum Cicadae, Fructus Canarii, Membrana Follicularis ovi, Herba Lophatheri, Radix Ophiopogonis, Fructus Arctii, Herba Dendrobii, Radix Glehniae, the Rhizoma Anemarrhenae, Radix Glycyrrhizae are put into machine for decocting Chinese traditional herb medicines, soak 10-20min, amount of water is 8-12 times of above-mentioned raw materials gross weight, decoct under 60-100 DEG C of condition, time is 1-3h, then filter, obtain filtrate and medicinal residues; Radix Scrophulariae after pulverizing in step (2), Rhizoma Phragmitis, Herba Menthae are put into machine for decocting Chinese traditional herb medicines and soak 10-20min, and amount of water is 8-12 times of above-mentioned raw materials gross weight, decocts under 60-100 DEG C of condition, time is 1-3h, then filters, and obtains filtrate and medicinal residues, after being merged by twice medicinal residues, amount of water is 5-10 times of medicinal residues gross weight, and decoct under 60-100 DEG C of condition, the time is 10-30min, then filter, get filtrate, dregs pressing goes out filtrate, four times filtrate merges, abandon medicinal residues, obtain filtrate A, for subsequent use;
(4) filter in step (3) in gained filtrate A feeding divergence type tube centrifuge, charging aperture pressure is greater than 0.05MPa, roller diameter 45-105mm, and revolution 10000-28000r/min, obtains liquor B, for subsequent use;
(5) filter in step (4) in gained liquor B feeding purpose ceramic-film filter, the aperture of ceramic membrane is 0.05 μm-1.4 μm, and pressure limit is 0.05-0.7MPa, and the scope of crossflow velocity is 4-6m/s, obtains liquor C, for subsequent use;
(6) gained liquor C in step (5) is sent into concentration tank, in concentration tank, be evaporated to the clear paste of relative density 1.01-1.08 during 50-60 DEG C, obtain clear paste D, for subsequent use;
(7) gained clear paste D in step (6) is carried out sterilization fill, select 450ml vial, vial is first scalded with the hot water of 70-85 DEG C, during bottling, clear paste temperature lower than 85 DEG C, must not seal after fill immediately, and sterilization temperature is 100-103 DEG C, time is 10-30min, after room temperature is down in cooling, warehouse-in is finished product, must treat the Chinese medicine oral liquid of chronic pharyngitis.
Preferably, a kind of preparation method for the treatment of the Chinese medicine oral liquid of chronic pharyngitis, is prepared from by following methods:
(1) raw material Semen Oroxyli, Periostracum Cicadae, Fructus Canarii, Membrana Follicularis ovi, Herba Lophatheri, Radix Ophiopogonis, Fructus Arctii, Herba Dendrobii, Radix Glehniae, the Rhizoma Anemarrhenae, Radix Glycyrrhizae cleaning is got, utilize hot-air seasoning after cleaning, hot blast wind speed is 2m/s, and drying time is 1h, 20 orders are ground into after oven dry, for subsequent use;
(2) get raw material Radix Scrophulariae, Rhizoma Phragmitis, Herba Menthae cleaning, utilize hot-air seasoning after cleaning, hot blast wind speed is 2m/s, and drying time is 1h, is ground into 20 orders after oven dry, for subsequent use;
(3) Semen Oroxyli after pulverizing in step (1), Periostracum Cicadae, Fructus Canarii, Membrana Follicularis ovi, Herba Lophatheri, Radix Ophiopogonis, Fructus Arctii, Herba Dendrobii, Radix Glehniae, the Rhizoma Anemarrhenae, Radix Glycyrrhizae are put into machine for decocting Chinese traditional herb medicines, soak 20min, amount of water is 12 times of above-mentioned raw materials gross weight, decoct under 83 DEG C of conditions, time is 1h, then filter, obtain filtrate and medicinal residues; Radix Scrophulariae after pulverizing in step (2), Rhizoma Phragmitis, Herba Menthae are then decocted under 83 DEG C of conditions, the time is 1h, then filters, obtain filtrate and medicinal residues, twice medicinal residues is merged 10 times that amount of water is above-mentioned raw materials gross weight, decocts under 75 DEG C of conditions, time is 30min, then filter, get filtrate, dregs pressing goes out filtrate, four times filtrate merges, abandon medicinal residues, obtain filtrate A, for subsequent use;
(4) filter in step (3) in gained filtrate A feeding divergence type tube centrifuge, charging aperture pressure is greater than 0.05MPa, roller diameter 105mm, and revolution 16500r/min, obtains liquor B, for subsequent use;
(5) filter in step (4) in gained liquor B feeding purpose ceramic-film filter, the aperture of ceramic membrane is 0.2 μm, and pressure is 0.05MPa, and crossflow velocity is 4m/s, obtains liquor C, for subsequent use;
(6) gained liquor C in step (5) is sent into concentration tank, when being evaporated to 60 DEG C in concentration tank, the clear paste of relative density 1.08, obtains clear paste D, for subsequent use;
(7) gained clear paste D in step (6) is carried out sterilization fill, select 450ml vial, vial is first scalded with the hot water of 83 DEG C, during bottling, clear paste temperature lower than 85 DEG C, must not seal after fill immediately, and sterilization temperature is 100 DEG C, time is 15min, after room temperature is down in cooling, warehouse-in is finished product, must treat the Chinese medicine oral liquid of chronic pharyngitis.
Beneficial effect: the present invention has nourishing YIN to lower pathogenic fire, strengthening vital QI to eliminate pathogenic factors, effect of antiinflammatory removing toxic substances, be a kind of safe and reliable, without any side effects, effective ingredient utilization rate is high, the Chinese medicine composition of instant effect.
The present invention adopts pure Chinese medicine to be raw material, according to pathogenic factor and the Clinical symptoms of chronic pharyngitis, under instruction of Chinese Medicine theory, carry out prescription be prepared from the basis not being raw-material activity, show through clinical efficacy, this medicine has definite curative effect to chronic pharyngitis, is a kind of ideal treatment medication of patients with chronic pharyngitis.
Model case
Case 1: Shi Nvshi, 33 years old, medical history: cough, hoarseness several days, once arrive hospital and to have an injection treatment, and loseed assorted effect, eat Chinese medicine, take Drug therapy of the present invention after 5 days patient's above-mentioned symptom disappear, follow up a case by regular visits to 1 year nothing and recur.
Case 2: Mrs Yao, 29 years old, medical history: more than private prosecution dry pharynx, pharyngalgia April, in larynx, mucus is many, takes Drug therapy of the present invention 5 days, and after treatment, patient's dry pharynx, pharyngalgia obviously alleviate, after taking two courses for the treatment of of medicine of the present invention, patient's above-mentioned symptom disappears, and follows up a case by regular visits to 1 year without recurrence.
Case 3: Mr. Fan, 47 years old, medical history: patient main suit, suffer from chronic pharyngitis 1 year, frequent dry pharynx causalgia, has foreign body sensation, and immediate cause is suffered from cold aggravation, with fever and cough, itching throat hoarseness, takes Drug therapy of the present invention 5 days, and after treatment, patient's dry pharynx, pharyngalgia obviously alleviate, after taking two courses for the treatment of of medicine of the present invention, patient's above-mentioned symptom disappears, and follows up a case by regular visits to 1 year without recurrence.
Case 4: Mrs Fang, 45 years old, medical history: because of dry cough 2 years, pharyngalgia, weak, aggravation 3 days of coughing, therefore examine, take Drug therapy of the present invention 5 days, patient's pharyngalgia after treatment, weak, cough obviously alleviate, and after taking three courses for the treatment of of medicine of the present invention, patient's above-mentioned symptom disappears, and follows up a case by regular visits to 1 year without recurrence.
Case 5: Mrs Shi, 35 years old, medical history: patient main suit's xerostomia, itching throat, pain, dry cough, suffer from chronic pharyngitis 1 year, examine, take Drug therapy of the present invention 5 days, after treatment, patient's xerostomia, itching throat, pain, dry cough obviously alleviate, after taking three courses for the treatment of of medicine of the present invention, patient's above-mentioned symptom disappears, and follows up a case by regular visits to 1 year without recurrence.
Case 6: Mr. Jiang, 34 years old, medical history: chronic pharyngitis is more than 3 years, and cough is frequent, ceaselessly in cough when patient comes, examine, take Drug therapy of the present invention 5 days, after treatment, patient coughs and obviously alleviates, and after taking three courses for the treatment of of medicine of the present invention, patient's above-mentioned symptom disappears, and follows up a case by regular visits to 1 year without recurrence.
Case 7: Mr. Bai, 75 years old, patient is conscious pharyngeally has thing to block 3 years, recently increases the weight of, cough, hoarseness several days, take Drug therapy of the present invention 5 days, after treatment, patient coughs and obviously alleviates, and after taking three courses for the treatment of of medicine of the present invention, patient's above-mentioned symptom disappears, and after taking two courses for the treatment of of medicine of the present invention, patient's above-mentioned symptom disappears, cure, follow up a case by regular visits to without recurrence.
Clinical data:
Physical data: patient 47 example, wherein man 27 example, female 20 example, the age be 15-65 year.
Diagnostic criteria: 1. medical history: patient has the medical history of acute pharyngitis recurrent exerbation, or have the situation of long-term mouth breathing; In addition, there are long-term tobacco and wine excessive, treat for a long time in the environment of drying, many, the irritant gas of dust; 2. clinical symptoms: the classical symptom of chronic pharyngitis: pharyngeal discomfort, or pain or itch or dry sensation, burning sensation, sootiness sense, foreign body sensation etc.; Irritable cough, plays firmly expectoration secretions morning, even feel sick, and the course of disease more than 2 months, the reasons such as Chang Yin suffers from cold, catch a cold, fatigue, polylogia are pathogenic; 3. inspect by instrument: if patient is through this inspect by instrument, visible pharyngeal chronic congestion, increases the weight of, and in kermesinus, or dendroid is congested; Retropharyneal folliculosis, or lateral pharyngeal band enlargement; Pharynx mucosa hypertrophy is plump, or drying, atrophy, thinning, has secretions to adhere to.
Therapeutic Method: take Chinese medicine oral liquid of the present invention, every day 2 times, each 30ml 5 days is 1 course for the treatment of.
Curative effect determinate standard: cure: pharyngeal transference cure, checks normal; Take a turn for the better: pharyngeal sings and symptoms obviously alleviates; Invalid: sings and symptoms is without significant change.
Therapeutic outcome: by this side treatment patients with chronic pharyngitis 47 example, cure 40 examples, take a turn for the better 7 examples, and invalid 0 example, total effective rate is 100%, has no any side effect.
Detailed description of the invention
Embodiment 1
The present invention treats the preparation of chronic pharyngitis Chinese medicine oral liquid, and the weight portion of each raw material is: Semen Oroxyli 18 parts, Radix Scrophulariae 18 parts, Rhizoma Phragmitis 33 parts, Periostracum Cicadae 18 parts, Fructus Canarii 15 parts, Herba Menthae 10 parts, Membrana Follicularis ovi 13 parts, Herba Lophatheri 23 parts, Radix Ophiopogonis 23 parts, Fructus Arctii 18 parts, Herba Dendrobii 23 parts, Radix Glehniae 23 parts, the Rhizoma Anemarrhenae 18 parts, 10 parts, Radix Glycyrrhizae;
Be prepared from by following methods:
(1) raw material Semen Oroxyli, Periostracum Cicadae, Fructus Canarii, Membrana Follicularis ovi, Herba Lophatheri, Radix Ophiopogonis, Fructus Arctii, Herba Dendrobii, Radix Glehniae, the Rhizoma Anemarrhenae, Radix Glycyrrhizae cleaning is got, utilize hot-air seasoning after cleaning, hot blast wind speed is 2-4m/s, and drying time is 1-12h, 10-20 order is ground into after oven dry, for subsequent use;
(2) get raw material Radix Scrophulariae, Rhizoma Phragmitis, Herba Menthae cleaning, utilize hot-air seasoning after cleaning, hot blast wind speed is 2-4m/s, and drying time is 1-12h, is ground into 10-20 order after oven dry, for subsequent use;
(3) Semen Oroxyli after pulverizing in step (1), Periostracum Cicadae, Fructus Canarii, Membrana Follicularis ovi, Herba Lophatheri, Radix Ophiopogonis, Fructus Arctii, Herba Dendrobii, Radix Glehniae, the Rhizoma Anemarrhenae, Radix Glycyrrhizae are put into machine for decocting Chinese traditional herb medicines, soak 10-20min, amount of water is 8-12 times of above-mentioned raw materials gross weight, decoct under 60-100 DEG C of condition, time is 1-3h, then filter, obtain filtrate and medicinal residues; Radix Scrophulariae after pulverizing in step (2), Rhizoma Phragmitis, Herba Menthae are put into machine for decocting Chinese traditional herb medicines and soak 10-20min, and amount of water is 8-12 times of above-mentioned raw materials gross weight, decocts under 60-100 DEG C of condition, time is 1-3h, then filters, and obtains filtrate and medicinal residues, after being merged by twice medicinal residues, amount of water is 5-10 times of medicinal residues gross weight, and decoct under 60-100 DEG C of condition, the time is 10-30min, then filter, get filtrate, dregs pressing goes out filtrate, four times filtrate merges, abandon medicinal residues, obtain filtrate A, for subsequent use;
(4) filter in step (3) in gained filtrate A feeding divergence type tube centrifuge, charging aperture pressure is greater than 0.05MPa, roller diameter 45-105mm, and revolution 10000-28000r/min, obtains liquor B, for subsequent use;
(5) filter in step (4) in gained liquor B feeding purpose ceramic-film filter, the aperture of ceramic membrane is 0.05 μm-1.4 μm, and pressure limit is 0.05-0.7MPa, and the scope of crossflow velocity is 4-6m/s, obtains liquor C, for subsequent use;
(6) gained liquor C in step (5) is sent into concentration tank, in concentration tank, be evaporated to the clear paste of relative density 1.01-1.08 during 50-60 DEG C, obtain clear paste D, for subsequent use;
(7) gained clear paste D in step (6) is carried out sterilization fill, select 450ml vial, vial is first scalded with the hot water of 70-85 DEG C, during bottling, clear paste temperature lower than 85 DEG C, must not seal after fill immediately, and sterilization temperature is 100-103 DEG C, time is 10-30min, after room temperature is down in cooling, warehouse-in is finished product, must treat the Chinese medicine oral liquid of chronic pharyngitis.
Usage: oral, every day 2 times, each 30ml.
Embodiment 2
The present invention treats the preparation of chronic pharyngitis Chinese medicine oral liquid, and the weight portion of each raw material is: Semen Oroxyli 15 parts, Radix Scrophulariae 15 parts, Rhizoma Phragmitis 30 parts, Periostracum Cicadae 15 parts, Fructus Canarii 12 parts, Herba Menthae 7 parts, Membrana Follicularis ovi 10 parts, Herba Lophatheri 20 parts, Radix Ophiopogonis 20 parts, Fructus Arctii 15 parts, Herba Dendrobii 20 parts, Radix Glehniae 20 parts, the Rhizoma Anemarrhenae 15 parts, 7 parts, Radix Glycyrrhizae;
Be prepared from by following methods:
(1) raw material Semen Oroxyli, Periostracum Cicadae, Fructus Canarii, Membrana Follicularis ovi, Herba Lophatheri, Radix Ophiopogonis, Fructus Arctii, Herba Dendrobii, Radix Glehniae, the Rhizoma Anemarrhenae, Radix Glycyrrhizae cleaning is got, utilize hot-air seasoning after cleaning, hot blast wind speed is 2-4m/s, and drying time is 1-12h, 10-20 order is ground into after oven dry, for subsequent use;
(2) get raw material Radix Scrophulariae, Rhizoma Phragmitis, Herba Menthae cleaning, utilize hot-air seasoning after cleaning, hot blast wind speed is 2-4m/s, and drying time is 1-12h, is ground into 10-20 order after oven dry, for subsequent use;
(3) Semen Oroxyli after pulverizing in step (1), Periostracum Cicadae, Fructus Canarii, Membrana Follicularis ovi, Herba Lophatheri, Radix Ophiopogonis, Fructus Arctii, Herba Dendrobii, Radix Glehniae, the Rhizoma Anemarrhenae, Radix Glycyrrhizae are put into machine for decocting Chinese traditional herb medicines, soak 10-20min, amount of water is 8-12 times of above-mentioned raw materials gross weight, decoct under 60-100 DEG C of condition, time is 1-3h, then filter, obtain filtrate and medicinal residues; Radix Scrophulariae after pulverizing in step (2), Rhizoma Phragmitis, Herba Menthae are put into machine for decocting Chinese traditional herb medicines and soak 10-20min, and amount of water is 8-12 times of above-mentioned raw materials gross weight, decocts under 60-100 DEG C of condition, time is 1-3h, then filters, and obtains filtrate and medicinal residues, after being merged by twice medicinal residues, amount of water is 5-10 times of medicinal residues gross weight, and decoct under 60-100 DEG C of condition, the time is 10-30min, then filter, get filtrate, dregs pressing goes out filtrate, four times filtrate merges, abandon medicinal residues, obtain filtrate A, for subsequent use;
(4) filter in step (3) in gained filtrate A feeding divergence type tube centrifuge, charging aperture pressure is greater than 0.05MPa, roller diameter 45-105mm, and revolution 10000-28000r/min, obtains liquor B, for subsequent use;
(5) filter in step (4) in gained liquor B feeding purpose ceramic-film filter, the aperture of ceramic membrane is 0.05 μm-1.4 μm, and pressure limit is 0.05-0.7MPa, and the scope of crossflow velocity is 4-6m/s, obtains liquor C, for subsequent use;
(6) gained liquor C in step (5) is sent into concentration tank, in concentration tank, be evaporated to the clear paste of relative density 1.01-1.08 during 50-60 DEG C, obtain clear paste D, for subsequent use;
(7) gained clear paste D in step (6) is carried out sterilization fill, select 450ml vial, vial is first scalded with the hot water of 70-85 DEG C, during bottling, clear paste temperature lower than 85 DEG C, must not seal after fill immediately, and sterilization temperature is 100-103 DEG C, time is 10-30min, after room temperature is down in cooling, warehouse-in is finished product, must treat the Chinese medicine oral liquid of chronic pharyngitis.
Usage: oral, every day 2 times, each 30ml.
Embodiment 3
The present invention treats the preparation of chronic pharyngitis Chinese medicine oral liquid, and the weight portion of each raw material is: Semen Oroxyli 12 parts, Radix Scrophulariae 12 parts, Rhizoma Phragmitis 27 parts, Periostracum Cicadae 12 parts, Fructus Canarii 9 parts, Herba Menthae 4 parts, Membrana Follicularis ovi 7 parts, Herba Lophatheri 17 parts, Radix Ophiopogonis 17 parts, Fructus Arctii 12 parts, Herba Dendrobii 17 parts, Radix Glehniae 17 parts, the Rhizoma Anemarrhenae 12 parts, 4 parts, Radix Glycyrrhizae;
Be prepared from by following methods:
(1) raw material Semen Oroxyli, Periostracum Cicadae, Fructus Canarii, Membrana Follicularis ovi, Herba Lophatheri, Radix Ophiopogonis, Fructus Arctii, Herba Dendrobii, Radix Glehniae, the Rhizoma Anemarrhenae, Radix Glycyrrhizae cleaning is got, utilize hot-air seasoning after cleaning, hot blast wind speed is 2-4m/s, and drying time is 1-12h, 10-20 order is ground into after oven dry, for subsequent use;
(2) get raw material Radix Scrophulariae, Rhizoma Phragmitis, Herba Menthae cleaning, utilize hot-air seasoning after cleaning, hot blast wind speed is 2-4m/s, and drying time is 1-12h, is ground into 10-20 order after oven dry, for subsequent use;
(3) Semen Oroxyli after pulverizing in step (1), Periostracum Cicadae, Fructus Canarii, Membrana Follicularis ovi, Herba Lophatheri, Radix Ophiopogonis, Fructus Arctii, Herba Dendrobii, Radix Glehniae, the Rhizoma Anemarrhenae, Radix Glycyrrhizae are put into machine for decocting Chinese traditional herb medicines, soak 10-20min, amount of water is 8-12 times of above-mentioned raw materials gross weight, decoct under 60-100 DEG C of condition, time is 1-3h, then filter, obtain filtrate and medicinal residues; Radix Scrophulariae after pulverizing in step (2), Rhizoma Phragmitis, Herba Menthae are put into machine for decocting Chinese traditional herb medicines and soak 10-20min, and amount of water is 8-12 times of above-mentioned raw materials gross weight, decocts under 60-100 DEG C of condition, time is 1-3h, then filters, and obtains filtrate and medicinal residues, after being merged by twice medicinal residues, amount of water is 5-10 times of medicinal residues gross weight, and decoct under 60-100 DEG C of condition, the time is 10-30min, then filter, get filtrate, dregs pressing goes out filtrate, four times filtrate merges, abandon medicinal residues, obtain filtrate A, for subsequent use;
(4) filter in step (3) in gained filtrate A feeding divergence type tube centrifuge, charging aperture pressure is greater than 0.05MPa, roller diameter 45-105mm, and revolution 10000-28000r/min, obtains liquor B, for subsequent use;
(5) filter in step (4) in gained liquor B feeding purpose ceramic-film filter, the aperture of ceramic membrane is 0.05 μm-1.4 μm, and pressure limit is 0.05-0.7MPa, and the scope of crossflow velocity is 4-6m/s, obtains liquor C, for subsequent use;
(6) gained liquor C in step (5) is sent into concentration tank, in concentration tank, be evaporated to the clear paste of relative density 1.01-1.08 during 50-60 DEG C, obtain clear paste D, for subsequent use;
(7) gained clear paste D in step (6) is carried out sterilization fill, select 450ml vial, vial is first scalded with the hot water of 70-85 DEG C, during bottling, clear paste temperature lower than 85 DEG C, must not seal after fill immediately, and sterilization temperature is 100-103 DEG C, time is 10-30min, after room temperature is down in cooling, warehouse-in is finished product, must treat the Chinese medicine oral liquid of chronic pharyngitis.
Usage: oral, every day 2 times, each 30ml.
Embodiment 4
The present invention treats the preparation of chronic pharyngitis Chinese medicine oral liquid, and the weight portion of each raw material is: Semen Oroxyli 14 parts, Radix Scrophulariae 14 parts, Rhizoma Phragmitis 29 parts, Periostracum Cicadae 14 parts, Fructus Canarii 11 parts, Herba Menthae 6 parts, Membrana Follicularis ovi 9 parts, Herba Lophatheri 19 parts, Radix Ophiopogonis 19 parts, Fructus Arctii 14 parts, Herba Dendrobii 19 parts, Radix Glehniae 19 parts, the Rhizoma Anemarrhenae 14 parts, 6 parts, Radix Glycyrrhizae;
Be prepared from by following methods:
(1) raw material Semen Oroxyli, Periostracum Cicadae, Fructus Canarii, Membrana Follicularis ovi, Herba Lophatheri, Radix Ophiopogonis, Fructus Arctii, Herba Dendrobii, Radix Glehniae, the Rhizoma Anemarrhenae, Radix Glycyrrhizae cleaning is got, utilize hot-air seasoning after cleaning, hot blast wind speed is 2-4m/s, and drying time is 1-12h, 10-20 order is ground into after oven dry, for subsequent use;
(2) get raw material Radix Scrophulariae, Rhizoma Phragmitis, Herba Menthae cleaning, utilize hot-air seasoning after cleaning, hot blast wind speed is 2-4m/s, and drying time is 1-12h, is ground into 10-20 order after oven dry, for subsequent use;
(3) Semen Oroxyli after pulverizing in step (1), Periostracum Cicadae, Fructus Canarii, Membrana Follicularis ovi, Herba Lophatheri, Radix Ophiopogonis, Fructus Arctii, Herba Dendrobii, Radix Glehniae, the Rhizoma Anemarrhenae, Radix Glycyrrhizae are put into machine for decocting Chinese traditional herb medicines, soak 10-20min, amount of water is 8-12 times of above-mentioned raw materials gross weight, decoct under 60-100 DEG C of condition, time is 1-3h, then filter, obtain filtrate and medicinal residues; Radix Scrophulariae after pulverizing in step (2), Rhizoma Phragmitis, Herba Menthae are put into machine for decocting Chinese traditional herb medicines and soak 10-20min, and amount of water is 8-12 times of above-mentioned raw materials gross weight, decocts under 60-100 DEG C of condition, time is 1-3h, then filters, and obtains filtrate and medicinal residues, after being merged by twice medicinal residues, amount of water is 5-10 times of medicinal residues gross weight, and decoct under 60-100 DEG C of condition, the time is 10-30min, then filter, get filtrate, dregs pressing goes out filtrate, four times filtrate merges, abandon medicinal residues, obtain filtrate A, for subsequent use;
(4) filter in step (3) in gained filtrate A feeding divergence type tube centrifuge, charging aperture pressure is greater than 0.05MPa, roller diameter 45-105mm, and revolution 10000-28000r/min, obtains liquor B, for subsequent use;
(5) filter in step (4) in gained liquor B feeding purpose ceramic-film filter, the aperture of ceramic membrane is 0.05 μm-1.4 μm, and pressure limit is 0.05-0.7MPa, and the scope of crossflow velocity is 4-6m/s, obtains liquor C, for subsequent use;
(6) gained liquor C in step (5) is sent into concentration tank, in concentration tank, be evaporated to the clear paste of relative density 1.01-1.08 during 50-60 DEG C, obtain clear paste D, for subsequent use;
(7) gained clear paste D in step (6) is carried out sterilization fill, select 450ml vial, vial is first scalded with the hot water of 70-85 DEG C, during bottling, clear paste temperature lower than 85 DEG C, must not seal after fill immediately, and sterilization temperature is 100-103 DEG C, time is 10-30min, after room temperature is down in cooling, warehouse-in is finished product, must treat the Chinese medicine oral liquid of chronic pharyngitis.
Usage: oral, every day 2 times, each 30ml.

Claims (7)

1. treat a Chinese medicine oral liquid for chronic pharyngitis, it is characterized in that: be made up of following raw material: Semen Oroxyli 12-18 part, Radix Scrophulariae 12-18 part, Rhizoma Phragmitis 27-33 part, Periostracum Cicadae 12-18 part, Fructus Canarii 9-15 part, Herba Menthae 4-10 part, Membrana Follicularis ovi 7-13 part, Herba Lophatheri 17-23 part, Radix Ophiopogonis 17-23 part, Fructus Arctii 12-18 part, Herba Dendrobii 17-23 part, Radix Glehniae 17-23 part, Rhizoma Anemarrhenae 12-18 part, Radix Glycyrrhizae 4-10 part.
2. a kind of Chinese medicine oral liquid for the treatment of chronic pharyngitis according to claim 1, is characterized in that: the weight portion of each raw material is: Semen Oroxyli 15 parts, Radix Scrophulariae 15 parts, Rhizoma Phragmitis 30 parts, Periostracum Cicadae 15 parts, Fructus Canarii 12 parts, Herba Menthae 7 parts, Membrana Follicularis ovi 10 parts, Herba Lophatheri 20 parts, Radix Ophiopogonis 20 parts, Fructus Arctii 15 parts, Herba Dendrobii 20 parts, Radix Glehniae 20 parts, the Rhizoma Anemarrhenae 15 parts, 7 parts, Radix Glycyrrhizae.
3. a kind of Chinese medicine oral liquid for the treatment of chronic pharyngitis according to claim 1, is characterized in that: the weight portion of each raw material is: Semen Oroxyli 14 parts, Radix Scrophulariae 14 parts, Rhizoma Phragmitis 29 parts, Periostracum Cicadae 14 parts, Fructus Canarii 11 parts, Herba Menthae 6 parts, Membrana Follicularis ovi 9 parts, Herba Lophatheri 19 parts, Radix Ophiopogonis 19 parts, Fructus Arctii 14 parts, Herba Dendrobii 19 parts, Radix Glehniae 19 parts, the Rhizoma Anemarrhenae 14 parts, 6 parts, Radix Glycyrrhizae.
4. a kind of Chinese medicine oral liquid for the treatment of chronic pharyngitis according to claim 1, is characterized in that: the weight portion of each raw material is: Semen Oroxyli 12 parts, Radix Scrophulariae 12 parts, Rhizoma Phragmitis 27 parts, Periostracum Cicadae 12 parts, Fructus Canarii 9 parts, Herba Menthae 4 parts, Membrana Follicularis ovi 7 parts, Herba Lophatheri 17 parts, Radix Ophiopogonis 17 parts, Fructus Arctii 12 parts, Herba Dendrobii 17 parts, Radix Glehniae 17 parts, the Rhizoma Anemarrhenae 12 parts, 4 parts, Radix Glycyrrhizae.
5. a kind of Chinese medicine oral liquid for the treatment of chronic pharyngitis according to claim 1, is characterized in that: the weight portion of each raw material is: Semen Oroxyli 18 parts, Radix Scrophulariae 18 parts, Rhizoma Phragmitis 33 parts, Periostracum Cicadae 18 parts, Fructus Canarii 15 parts, Herba Menthae 10 parts, Membrana Follicularis ovi 13 parts, Herba Lophatheri 23 parts, Radix Ophiopogonis 23 parts, Fructus Arctii 18 parts, Herba Dendrobii 23 parts, Radix Glehniae 23 parts, the Rhizoma Anemarrhenae 18 parts, 10 parts, Radix Glycyrrhizae.
6. a kind of preparation method for the treatment of the Chinese medicine oral liquid of chronic pharyngitis according to claim 1 and 2, is characterized in that: be prepared from by following methods:
(1) raw material Semen Oroxyli, Periostracum Cicadae, Fructus Canarii, Membrana Follicularis ovi, Herba Lophatheri, Radix Ophiopogonis, Fructus Arctii, Herba Dendrobii, Radix Glehniae, the Rhizoma Anemarrhenae, Radix Glycyrrhizae cleaning is got, utilize hot-air seasoning after cleaning, hot blast wind speed is 2-4m/s, and drying time is 1-12h, 10-20 order is ground into after oven dry, for subsequent use;
(2) get raw material Radix Scrophulariae, Rhizoma Phragmitis, Herba Menthae cleaning, utilize hot-air seasoning after cleaning, hot blast wind speed is 2-4m/s, and drying time is 1-12h, is ground into 10-20 order after oven dry, for subsequent use;
(3) Semen Oroxyli after pulverizing in step (1), Periostracum Cicadae, Fructus Canarii, Membrana Follicularis ovi, Herba Lophatheri, Radix Ophiopogonis, Fructus Arctii, Herba Dendrobii, Radix Glehniae, the Rhizoma Anemarrhenae, Radix Glycyrrhizae are put into machine for decocting Chinese traditional herb medicines, soak 10-20min, amount of water is 8-12 times of above-mentioned raw materials gross weight, decoct under 60-100 DEG C of condition, time is 1-3h, then filter, obtain filtrate and medicinal residues; Radix Scrophulariae after pulverizing in step (2), Rhizoma Phragmitis, Herba Menthae are put into machine for decocting Chinese traditional herb medicines and soak 10-20min, and amount of water is 8-12 times of above-mentioned raw materials gross weight, decocts under 60-100 DEG C of condition, time is 1-3h, then filters, and obtains filtrate and medicinal residues, after being merged by twice medicinal residues, amount of water is 5-10 times of medicinal residues gross weight, and decoct under 60-100 DEG C of condition, the time is 10-30min, then filter, get filtrate, dregs pressing goes out filtrate, four times filtrate merges, abandon medicinal residues, obtain filtrate A, for subsequent use;
(4) filter in step (3) in gained filtrate A feeding divergence type tube centrifuge, charging aperture pressure is greater than 0.05MPa, roller diameter 45-105mm, and revolution 10000-28000r/min, obtains liquor B, for subsequent use;
(5) filter in step (4) in gained liquor B feeding purpose ceramic-film filter, the aperture of ceramic membrane is 0.05 μm-1.4 μm, and pressure limit is 0.05-0.7MPa, and the scope of crossflow velocity is 4-6m/s, obtains liquor C, for subsequent use;
(6) gained liquor C in step (5) is sent into concentration tank, in concentration tank, be evaporated to the clear paste of relative density 1.01-1.08 during 50-60 DEG C, obtain clear paste D, for subsequent use;
(7) gained clear paste D in step (6) is carried out sterilization fill, select 450ml vial, vial is first scalded with the hot water of 70-85 DEG C, during bottling, clear paste temperature lower than 85 DEG C, must not seal after fill immediately, and sterilization temperature is 100-103 DEG C, time is 10-30min, after room temperature is down in cooling, warehouse-in is finished product, must treat the Chinese medicine oral liquid of chronic pharyngitis.
7. a kind of preparation method for the treatment of the Chinese medicine oral liquid of chronic pharyngitis according to claim 1 and 2, is characterized in that: be prepared from by following methods:
(1) raw material Semen Oroxyli, Periostracum Cicadae, Fructus Canarii, Membrana Follicularis ovi, Herba Lophatheri, Radix Ophiopogonis, Fructus Arctii, Herba Dendrobii, Radix Glehniae, the Rhizoma Anemarrhenae, Radix Glycyrrhizae cleaning is got, utilize hot-air seasoning after cleaning, hot blast wind speed is 2m/s, and drying time is 1h, 20 orders are ground into after oven dry, for subsequent use;
(2) get raw material Radix Scrophulariae, Rhizoma Phragmitis, Herba Menthae cleaning, utilize hot-air seasoning after cleaning, hot blast wind speed is 2m/s, and drying time is 1h, is ground into 20 orders after oven dry, for subsequent use;
(3) Semen Oroxyli after pulverizing in step (1), Periostracum Cicadae, Fructus Canarii, Membrana Follicularis ovi, Herba Lophatheri, Radix Ophiopogonis, Fructus Arctii, Herba Dendrobii, Radix Glehniae, the Rhizoma Anemarrhenae, Radix Glycyrrhizae are put into machine for decocting Chinese traditional herb medicines, soak 20min, amount of water is 12 times of above-mentioned raw materials gross weight, decoct under 83 DEG C of conditions, time is 1h, then filter, obtain filtrate and medicinal residues; Radix Scrophulariae after pulverizing in step (2), Rhizoma Phragmitis, Herba Menthae are then decocted under 83 DEG C of conditions, the time is 1h, then filters, obtain filtrate and medicinal residues, twice medicinal residues is merged 10 times that amount of water is above-mentioned raw materials gross weight, decocts under 75 DEG C of conditions, time is 30min, then filter, get filtrate, dregs pressing goes out filtrate, four times filtrate merges, abandon medicinal residues, obtain filtrate A, for subsequent use;
(4) filter in step (3) in gained filtrate A feeding divergence type tube centrifuge, charging aperture pressure is greater than 0.05MPa, roller diameter 105mm, and revolution 16500r/min, obtains liquor B, for subsequent use;
(5) filter in step (4) in gained liquor B feeding purpose ceramic-film filter, the aperture of ceramic membrane is 0.2 μm, and pressure is 0.05MPa, and crossflow velocity is 4m/s, obtains liquor C, for subsequent use;
(6) gained liquor C in step (5) is sent into concentration tank, when being evaporated to 60 DEG C in concentration tank, the clear paste of relative density 1.08, obtains clear paste D, for subsequent use;
(7) gained clear paste D in step (6) is carried out sterilization fill, select 450ml vial, vial is first scalded with the hot water of 83 DEG C, during bottling, clear paste temperature lower than 85 DEG C, must not seal after fill immediately, and sterilization temperature is 100 DEG C, time is 15min, after room temperature is down in cooling, warehouse-in is finished product, must treat the Chinese medicine oral liquid of chronic pharyngitis.
CN201510755390.8A 2015-11-09 2015-11-09 Traditional Chinese medicine oral solution for treating chronic pharyngitis and preparation method of traditional Chinese medicine oral solution Pending CN105250771A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106377694A (en) * 2016-11-11 2017-02-08 东莞市百替生物科技有限公司 Traditional Chinese medicine composition for treating chronic pharyngitis and preparation method thereof
CN106389876A (en) * 2016-11-11 2017-02-15 东莞市百替生物科技有限公司 Traditional Chinese medicine composition for curing chronic pharyngitis and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101979060A (en) * 2010-11-05 2011-02-23 张沁 Chinese medicament for treating pharyngitis
CN104474323A (en) * 2014-11-27 2015-04-01 李坤 Medicine for treating chronic pharyngitis and preparation method of medicine

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101979060A (en) * 2010-11-05 2011-02-23 张沁 Chinese medicament for treating pharyngitis
CN104474323A (en) * 2014-11-27 2015-04-01 李坤 Medicine for treating chronic pharyngitis and preparation method of medicine

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106377694A (en) * 2016-11-11 2017-02-08 东莞市百替生物科技有限公司 Traditional Chinese medicine composition for treating chronic pharyngitis and preparation method thereof
CN106389876A (en) * 2016-11-11 2017-02-15 东莞市百替生物科技有限公司 Traditional Chinese medicine composition for curing chronic pharyngitis and preparation method thereof

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