CN105169058A - Snake gall bulbus fritilariae cough syrup and preparation method thereof - Google Patents
Snake gall bulbus fritilariae cough syrup and preparation method thereof Download PDFInfo
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- CN105169058A CN105169058A CN201510625849.2A CN201510625849A CN105169058A CN 105169058 A CN105169058 A CN 105169058A CN 201510625849 A CN201510625849 A CN 201510625849A CN 105169058 A CN105169058 A CN 105169058A
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Abstract
The invention relates to snake gall bulbus fritilariae cough syrup and a preparation method thereof, and belongs to the technical field of Chinese herbal medicines. According to the snake gall bulbus fritilariae cough syrup and the preparation method thereof, from a motherland medicine treasure house, cortex mori radicis which can clearing lung heat and relieve a cough and asthma is selected to serve as a monarch drug, cortex lycii radicis, snake bile, bulbus fritillariae cirrhosae and scutellaria baicalensis which can clear heat, moisten the lungs, dissipate phlegm and relieve the cough are selected to serve as ministerial drugs, rhizoma phragmitis which can clear heat, purge fire and promote secretion of saliva or the body fluid and pericarpium citri reticulatae which can strengthen the spleens, regulate qi and dissipate phlegm are selected to serve as adjuvant drugs, honey-fried licorice roots which can nourish the stomach, regulate the middle warmer, relieve the cough, dissipate phlegm and coordinate all the medicines are selected to serve as conductant drugs; the whole formula jointly achieves the effects of clearing heat, moistening the lungs, dissipating phlegm and relieving the cough. The snake gall bulbus fritilariae cough syrup is suitable for the symptoms of excessive phlegm and cough caused by respiratory tract tracheal diseases, has the advantages of being reasonable in cost, few in toxic and side effects, convenient to take, rapid in curative effect and capable of eradicating the disease pain and solves the problems that existing cough relieving drugs mostly have certain side effects, can only relieve the symptoms, but cannot fundamentally dispel the disease pain. The snake gall bulbus fritilariae cough syrup can be produced in batches, is wide in suitable crowds and has the extremely high promotional value.
Description
Technical field
The present invention relates to a kind of shake bile-fritillary cough syrup and preparation method thereof, belong to field of Chinese herbal medicine technology.
Background technology
Weather dry autumn of feeling nice and cool is multiple season of respiratory tract trachea aspect disease.Theory of Chinese medical science is thought; Lung governing skin and hair, excess of YANG bringing about heat syndrome, excess of YIN bringing about cold syndrome; Insufficiency of YANG bringing about exterior-cold symptoms, deficiency of YIN bringing about interior heat; Yang predomination generating heat, excess of YIN bringing about interior-cold syndrome.Lung governing qi, department breathes, and the deficiency of the lung is cough with asthma thin sputum then; Wind and cold bag lung then cough and asthma, the not thirsty normal wake thin nasal discharge of mouth.Wind-heat invading the lung is not easily expectoration then, and with dysphoria; Deficiency of lung-YIN is deficiency of body fluid then, sputum mixed with blood.Yang-energy gradually closing in autumn, cloudy gas growth is the transition period of human body YANG declining when YIN growing.The conditioning using Chinese medicine to carry out protecting lung lung moistening within the transition period has good curative effect to the cough for the treatment of abundant expectoration.But existing cough-relieving medicine has certain side effect mostly, and can only relief of symptoms, fundamentally can not dispel slight illness.
Summary of the invention
The object of the invention is to: provide a kind of suitability strong, good effect, and shake bile-fritillary cough syrup had no side effect and preparation method thereof.
The present invention realizes above-mentioned purpose by the following technical solutions:
A kind of shake bile-fritillary cough syrup, is characterized in that: it is (to prepare 1000 milliliters of medicinal liquid gauge) be made up of the raw material of following weight portion:
Cortex Lycii 25-35g Cortex Mori 25-35g
Fel Serpentis 1-4g Bulbus Fritillariae Cirrhosae 10-18g
Radix Scutellariae 8-12g Rhizoma Phragmitis 12-20g
Pericarpium Citri Reticulatae 8-12g Radix Glycyrrhizae Preparata 4-8g
Ethanol 450-600 adds water to 1000 milliliters.
The formulation optimization weight scope preparing shake bile-fritillary syrup of the present invention is (to prepare 1000 milliliters of medicinal liquid gauge):
Cortex Lycii 28-33g Cortex Mori 28-33g
Fel Serpentis 1-3g Bulbus Fritillariae Cirrhosae 12-16g
Radix Scutellariae 9-11g Rhizoma Phragmitis 13-18g
Pericarpium Citri Reticulatae 9-11g Radix Glycyrrhizae Preparata 5-7g
Ethanol 480-550 adds water to 1000 milliliters.
The formula optimum weight part ratio range preparing shake bile-fritillary syrup of the present invention is (to prepare 1000 milliliters of medicinal liquid gauge):
Cortex Lycii 30g Cortex Mori 30g
Fel Serpentis 2g Bulbus Fritillariae Cirrhosae 15g
Radix Scutellariae 10g Rhizoma Phragmitis 15g
Pericarpium Citri Reticulatae 10g Radix Glycyrrhizae Preparata 6g
Ethanol 500 adds water to 1000 milliliters.
Its preparation method is:
1, by above-mentioned raw materials medicine Bulbus Fritillariae Cirrhosae, be 80% alcohol dipping, 48 hours post-heating reflux, extract, with mass ratio, extracting solution filters, and filtrate is condensed into extractum.
2, Cortex Lycii, Cortex Mori, Radix Scutellariae, Rhizoma Phragmitis, Pericarpium Citri Reticulatae, Radix Glycyrrhizae Preparata are decocted with water twice, 2 hours first times, second time 1.5 hours, collecting decoction, filtration, filtrate are concentrated in right amount.
3, be mixed with step 2 gained filtrate after step 1 gained extractum being added Fel Serpentis, add water to 1000mL and stir, gained liquid, by after specification fill, sterilizing, obtains shake bile-fritillary syrup finished product.
In the raw material that the present invention is above-mentioned, property feature and effect of each crude drug are as follows:
Cortex Lycii:
Property feature: cold in nature, sweet in the mouth.Enter lung, liver, kidney channel.
Effect: removing heat from blood removes and steams, lung heat clearing pathogenic fire reducing.For deficiency of YIN hectic fever, hectic fever due to YIN-deficiency night sweat, cough due to lung-heat, spitting of blood, epistaxis.
Cortex Mori:
Property feature: sweet, cold.Return lung meridian.
Effect: eliminating pathogen from the lung for relieving asthma, inducing diuresis to remove edema.For lung-heat cough with asthma, edema distension.
Fel Serpentis:
Property feature: sweet, micro-hardship is cool.Return lung, gallbladder, spleen, liver, large intestine, small intestine meridian.
Effect: heat-clearing and toxic substances removing, spasmolytic of reducing phlegm.For infantile pneumonia, pertussis, bronchitis, cough phlegm dyspnea, expectorant febrile convulsion, acute rheumatic arthritis.
Bulbus Fritillariae Cirrhosae:
Property feature: bitter in the mouth, sweet, cold nature.Return lung, heart channel.
Effect: clearing heat and moistening lung, preventing phlegm from forming and stopping coughing, eliminating stagnation eliminating carbuncle.For lung-heat type cough, the few expectorant of dry cough, deficiency of YIN impairment and cough, sputum mixed with blood, scrofula, acute mastitis, lung abscess.
Radix Scutellariae:
Property feature: bitter in the mouth, cold in nature.Return lung, gallbladder, spleen, large intestine, small intestine meridian.
Effect: heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive.For hygropyrexia, heat-damp in summer, vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood tells nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.
Rhizoma Phragmitis:
Property feature: sweet, cold.Attach to the lung and stomach meridians.
Effect: clearing away heat-fire, promoting the production of body fluid to quench thirst, relieving restlessness, preventing or arresting vomiting, diuresis.For calentura excessive thirst, lung-heat type cough, interior-heat is quenched one's thirst, sore swollen toxin.
Pericarpium Citri Reticulatae:
Property feature: bitter in the mouth, pungent, warm in nature.Return lung, spleen channel.
Effect: regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.For distension and fullness in the abdomen, lack of appetite and vomiting, cough with copious phlegm.
Radix Glycyrrhizae Preparata (Radix Glycyrrhizae):
Property feature: sweet in the mouth, property is put down.GUIXIN, lung, spleen, stomach warp.
Effect: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
The present invention is according to the theory of Chinese medical science of motherland's medicine, and with reference to modern pharmacological research achievement, from motherland's medicine treasure-house, the clear eliminating the pathogens from the lung of selected Cortex Mori is hot, and relieving cough and asthma is monarch drug; Cortex Lycii, Fel Serpentis, Bulbus Fritillariae Cirrhosae, Radix Scutellariae clearing heat and moistening lung, preventing phlegm from forming and stopping coughing is ministerial drug; Rhizoma Phragmitis clearing away heat-fire promotes the production of body fluid, Pericarpium Citri Reticulatae spleen invigorating activating QI to eliminate phlegm, is adjuvant drug; Radix Glycyrrhizae Preparata nourishing the stomach and in, relieving cough and resolving phlegm, coordinating the actions of various ingredients in a prescription is adjuvant.Full side plays clearing heat and moistening lung altogether, the merit of preventing phlegm from forming and stopping coughing.
Preparation specification of the present invention is bottled, every bottle of 10ml.
Usage of the present invention and consumption: oral, every day 2 times, each 10ml, children's is cut down according to the circumstance or is followed the doctor's advice.
Beneficial effect of the present invention is:
The present invention has clearing heat and moistening lung, effect of preventing phlegm from forming and stopping coughing, the symptom of the abundant expectoration cough caused by respirability road tracheal disease, have that cost is reasonable, toxic and side effects is little, the feature that taking convenience, curative effect are short, elimination is ailing, solve existing cough-relieving medicine and mostly have certain side effect, and can only relief of symptoms, fundamentally can not dispel ailing problem.The present invention can produce in batches, and suitable population is extensive, has high promotional value.
In order to show therapeutic effect of the present invention, the present invention is by having carried out system clinical observation to 150 routine patients, and its concrete outcome is as follows:
1, physical data:
150 routine patients are clinic case, and wherein male is 75, and women is 75, wherein 65 years old maximum patient age, minimum patient age 5 years old.
2, Therapeutic Method:
Above-mentioned 150 routine patients all take QINGRE JIEDU KOUFUYE of the present invention, every day 2 times, each 10ml, and children's is cut down according to the circumstance, and within 5 days, are a course for the treatment of.
The 150 routine patients using shake bile-fritillary syrup of the present invention and the 150 routine patients taking other nourishing the lung to arrest cough medicines carry out contrast therapy, and concrete outcome is as follows:
Detailed description of the invention
Embodiment 1:
To prepare 1000 milliliters of medicinal liquid gauge, take each raw material (unit: gram) by following weight;
Cortex Lycii 34g Cortex Mori 34g
Fel Serpentis 3g Bulbus Fritillariae Cirrhosae 17g
Radix Scutellariae 12g Rhizoma Phragmitis 18g
Pericarpium Citri Reticulatae 12g Radix Glycyrrhizae Preparata 8g
Ethanol 450g adds water to 1000 milliliters.
By above-mentioned raw materials medicine Bulbus Fritillariae Cirrhosae, be 80% alcohol dipping, 48 hours post-heating reflux, extract, with 450g mass ratio, extracting solution filters, and filtrate is condensed into extractum.Cortex Mori, Cortex Lycii, Radix Scutellariae, Rhizoma Phragmitis, Pericarpium Citri Reticulatae, Radix Glycyrrhizae Preparata are decocted with water twice, 2 hours first times, second time 1.5 hours, collecting decoction, filtration, filtrate are concentrated in right amount simultaneously.After being mixed with above filtrate after subsequently gained extractum being added Fel Serpentis, add water to 1000mL and stir, gained liquid, by after specification fill, sterilizing, obtains shake bile-fritillary syrup.
Embodiment 2:
To prepare 1000 milliliters of medicinal liquid gauge, take each raw material (unit: gram) by following weight;
Cortex Lycii 28g Cortex Mori 29g
Fel Serpentis 1g Bulbus Fritillariae Cirrhosae 13g
Radix Scutellariae 9g Rhizoma Phragmitis 14g
Pericarpium Citri Reticulatae 9g Radix Glycyrrhizae Preparata 5g
Ethanol 550g adds water to 1000 milliliters.
By above-mentioned raw materials medicine Bulbus Fritillariae Cirrhosae, be 80% alcohol dipping, 48 hours post-heating reflux, extract, with 550g mass ratio, extracting solution filters, and filtrate is condensed into extractum.Cortex Mori, Cortex Lycii, Radix Scutellariae, Rhizoma Phragmitis, Pericarpium Citri Reticulatae, Radix Glycyrrhizae Preparata are decocted with water twice, 2 hours first times, second time 1.5 hours, collecting decoction, filtration, filtrate are concentrated in right amount simultaneously.After being mixed with above filtrate after subsequently gained extractum being added Fel Serpentis, add water to 1000mL and stir, gained liquid, by after specification fill, sterilizing, obtains shake bile-fritillary syrup.
Embodiment 3:
To prepare 1000 milliliters of medicinal liquid gauge, take each raw material (unit: gram) by following weight;
Cortex Lycii 30g Cortex Mori 30g
Fel Serpentis 2g Bulbus Fritillariae Cirrhosae 15g
Radix Scutellariae 10g Rhizoma Phragmitis 15g
Pericarpium Citri Reticulatae 10g Radix Glycyrrhizae Preparata 6g
Ethanol 500 adds water to 1000 milliliters.
By above-mentioned raw materials medicine Bulbus Fritillariae Cirrhosae, be 80% alcohol dipping, 48 hours post-heating reflux, extract, with 500g mass ratio, extracting solution filters, and filtrate is condensed into extractum.Cortex Mori, Cortex Lycii, Radix Scutellariae, Rhizoma Phragmitis, Pericarpium Citri Reticulatae, Radix Glycyrrhizae Preparata are decocted with water twice, 2 hours first times, second time 1.5 hours, collecting decoction, filtration, filtrate are concentrated in right amount simultaneously.After being mixed with above filtrate after subsequently gained extractum being added Fel Serpentis, add water to 1000mL and stir, gained liquid, by after specification fill, sterilizing, obtains shake bile-fritillary syrup.
Claims (3)
1. a shake bile-fritillary syrup, is characterized in that: it is made up of the raw material of following weight portion:
Cortex Lycii 25-35g Cortex Mori 25-35g
Fel Serpentis 1-4g Bulbus Fritillariae Cirrhosae 10-18g
Radix Scutellariae 8-12g Rhizoma Phragmitis 12-20g
Pericarpium Citri Reticulatae 8-12g Radix Glycyrrhizae Preparata 4-8g
Ethanol 450-600g adds water to 1000 milliliters;
The preparation method of above-mentioned shake bile-fritillary syrup comprises the following steps:
1), by above-mentioned raw materials medicine Bulbus Fritillariae Cirrhosae, be 80% alcohol dipping, 48 hours post-heating reflux, extract, with 500g mass ratio, extracting solution filters, and filtrate is condensed into extractum;
2), by Cortex Mori, Cortex Lycii, Radix Scutellariae, Rhizoma Phragmitis, Pericarpium Citri Reticulatae, Radix Glycyrrhizae Preparata decoct with water twice, 2 hours first times, second time 1.5 hours, collecting decoction, filtration, filtrate are concentrated in right amount;
3), step 1 gained extractum is added Fel Serpentis after be mixed with step 2 gained filtrate after, add water to 1000mL and stir, gained liquid, by specification fill, after sterilizing, obtains shake bile-fritillary syrup finished product.
2. a kind of shake bile-fritillary syrup according to claim 1, is characterized in that: it is made up of the raw material of following weight portion:
Cortex Lycii 28-33g Cortex Mori 28-33g
Fel Serpentis 1-3g Bulbus Fritillariae Cirrhosae 12-16g
Radix Scutellariae 9-11g Rhizoma Phragmitis 13-18g
Pericarpium Citri Reticulatae 9-11g Radix Glycyrrhizae Preparata 5-7g
Ethanol 480-550g adds water to 1000 milliliters.
3. a kind of shake bile-fritillary syrup according to claim 1, is characterized in that: it is made up of the raw material of following weight portion:
Cortex Lycii 30g Cortex Mori 30g
Fel Serpentis 2g Bulbus Fritillariae Cirrhosae 15g
Radix Scutellariae 10g Rhizoma Phragmitis 15g
Pericarpium Citri Reticulatae 10g Radix Glycyrrhizae Preparata 6g
Ethanol 500g adds water to 1000 milliliters.
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| CN201510625849.2A CN105169058A (en) | 2015-09-28 | 2015-09-28 | Snake gall bulbus fritilariae cough syrup and preparation method thereof |
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| CN201510625849.2A CN105169058A (en) | 2015-09-28 | 2015-09-28 | Snake gall bulbus fritilariae cough syrup and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108578561A (en) * | 2018-06-14 | 2018-09-28 | 广西玉兰制药有限公司 | A kind of Fel Serpentis et Bulbus Fritillariae Cirrhosae Liquidus and preparation method thereof |
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| JP2007254414A (en) * | 2006-03-24 | 2007-10-04 | Musashino Meneki Kenkyusho:Kk | Antitussive composition containing extract of plant of genus bidens |
| CN103656131A (en) * | 2012-08-31 | 2014-03-26 | 杨波 | Drug composition for treating cough |
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2015
- 2015-09-28 CN CN201510625849.2A patent/CN105169058A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007254414A (en) * | 2006-03-24 | 2007-10-04 | Musashino Meneki Kenkyusho:Kk | Antitussive composition containing extract of plant of genus bidens |
| CN103656131A (en) * | 2012-08-31 | 2014-03-26 | 杨波 | Drug composition for treating cough |
Non-Patent Citations (2)
| Title |
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| 李永来: "《中华名方大全》", 31 January 2013, 黑龙江科学技术出版社 * |
| 赖天松: "《中西医汇通常用方剂》", 31 March 2000, 广东科技出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108578561A (en) * | 2018-06-14 | 2018-09-28 | 广西玉兰制药有限公司 | A kind of Fel Serpentis et Bulbus Fritillariae Cirrhosae Liquidus and preparation method thereof |
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Application publication date: 20151223 |
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