CN104623148A - Medicament for treating cough and asthma and preparation method of oral liquid thereof - Google Patents
Medicament for treating cough and asthma and preparation method of oral liquid thereof Download PDFInfo
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Abstract
Disclosed is a medicament for treating cough and asthma. The medicament is composed of the following raw herbs, by weight: 1-20 parts of ephedra stem, 1-20 parts of apricot kernel, 10-30 parts of gypsum, 1-30 parts of Chinese magnoliavine, 1-20 parts of white peony root, 1-20 parts of asarum herb, 10-30 parts of pinellia ternata, 10-40 parts of balloonflower root, 1-30 parts of tatarian aster root, and 1-20 parts of licorice. According to the invention, the main medicine ingredients, such as ephedra stems, apricot kernels and tatarian aster roots, have the functions of treating cough and asthma, and other ingredients, which have the effects of tonifying the spleen and replenishing qi, clearing lung-heat and moisturizing dryness, and relieving cough and moistening the lung, assist in treating cough and asthma, so that obvious therapeutic effects can be obtained. According to the invention, a preparation method of oral liquid is simple; the leached oral liquid can be quickly absorbed by a human body and is fast in dose-response; and the dose of the oral liquid is small due to condensation technology, and thus the oral liquid is easy to carry, preserve and take.
Description
Technical field
The invention belongs to a kind of Chinese medicine composition, be specifically related to the treatment medicine of cough with asthma and the preparation method of oral liquid thereof
.
Background technology
Cough with asthma is the cardinal symptom of pneumonopathy.The cause of disease of cough with asthma has Exogenous and internal injuries not, and pathogenesis has dividing of cold and heat and asthenia and sthenia.Cough with asthma and expectorant closely related, cough with asthma often more presss from both sides expectorant, and expectorant also often causes cough with asthma.
Traditional Chinese Medicine is thought: cough with asthma morbidity root " be marked on lung, this is at spleen, and root is at kidney ", " deficiency of the lung is then coughed, and spleen deficiency generating phlegm, failure of the kidney in receiving QI are then breathed heavily ".If lung, spleen, renal dysfunction, just there will be sputum and deposit in a large number, respiratory inflammation constantly spreads, thus causes in cough with asthma.Cough with asthma and cough are the rapid superinverses of lung qi, and to sending " coughing " sample sound under the pressure of glottis, normal a kind of symptom of accompanying spoonful feature of coughing up phlegm, it is sound without expectorant that Gu coughs meaning, and meaning of coughing is noiseless and have dividing of expectorant, and actual being difficult to completely divides.Cough with asthma and cough are the cardinal symptoms of lung pattern disease, unclear by lung qi, lose in a surname respectful, caused by abnormal rising of lung-QI.Other visceral dysfunctions cause abnormal rising of lung-QI also can occur cough with asthma and cough.Cough with asthma and having coughed for a long time, also can consume gas Tianjin, and infringement body, play is coughed and also can be caused adverse consequences.The cause of disease of cough with asthma and cough has diseases caused by exogenous pathogenic factor, internal injury; Calcium entry is due to abrupt change of climate or take good care of oneself inappropriate, and diseases caused by exogenous pathogenic factor six climate exopathogens invade from mouth and nose or fur, lung qi are restrainted, impairment of purifying and descending function of the lung.The internal injury cause of disease comprises diet, feelings will and lungs from sick.The outbreak of cough with asthma and cough has acute cough with asthma and cough, chronic cough and asthma and cough.Acute cough with asthma and cough, companion's symptoms of chill and fever, mostly are caused by diseases caused by exogenous pathogenic factor, have the causes of disease such as wind and cold, wind heat, pathogenic dryness.Chronic cough and asthma and cough, the symptoms such as companion dyspnea with rapid and short breath, cardiopalmus, hypochondriac pain, mostly are caused by internal injury, caused by lung or other internal organs pathological changes.Doctor trained in Western medicine is thought, cough with asthma and cough are Physiological protection actions sexual reflex, respiratory tract foreign body or secretions can be excreted; Also having pathologic on the other hand, is one of respiratory system common sympton.When organs such as ear, nose, throat, bronchus, pleura, lungs, when stimulating by inflammation, congestion, physics, chemistry or the factor such as irritated, be distributed in the vagus nerve branch of these organs, be just communicated to oblongata cough with asthma and coughing centre, cause cough with asthma and coughre flex.
Current western medical treatment cough with asthma, asthma, tracheitis generally the most often select the medicine of expansion bronchus, as: aminophylline, clenbuterol, salbutamol etc.Air flue can be expanded rapidly, remove spasm, increase ventilation, eliminate symptom, shortcoming to be effected a radical cure, and easy drug resistance, another kind of common medicine are hormone, all effective to asthma tracheitis, the side effect of prolonged application medicine is larger, air flue aerosol therapy is more popular at present, and side effect is relatively less, but medical expense is higher.
Oral liquid absorbs the process characteristic of Chinese medicine, by decoction refining, concentrated, embedding further, sterilizing and obtaining.Oral liquid is come across market, as Oral Liquid Radix Panacis Quinquefolii, Ferulic acid etc. with a kind of form of health product the earliest; And recently, many curative oral liquids emerge in multitude in the formulation, as YINHUANG KOUFUYE, antivirus oral liquid, QINGRE JIEDU KOUFUYE etc., and by increasing popular good, there is following advantage in oral liquid formulations, comprehensively can leach the functional component in raw material, play the drug effect that it is comprehensive; Absorb fast, dose-effect is rapid; Can produce in enormous quantities, remove the trouble that consumer does it yourself to make from, taking convenience.
Summary of the invention
Easily recur for prior art western medicine, other therapies problem such as costly, the invention provides a kind of evident in efficacy, preparation is convenient, the medicine for the treatment of cough with asthma, and technique this drug oral liquid and preparation method thereof simple
.
To achieve these goals, the technical solution used in the present invention is: the medicine for the treatment of cough with asthma, and this Chinese medicine composition is made up of the crude drug of following weight portion: Herba Ephedrae 1-20 part, Semen Armeniacae Amarum 1-20 part, Gypsum Fibrosum 10-30 part, Fructus Schisandrae Chinensis 1-30 part, Radix Paeoniae Alba 1-20 part, Herba Asari 1-20 part, Rhizoma Pinelliae 10-30 part, Radix Platycodonis 10-40 part, Radix Asteris 1-30 part, Radix Glycyrrhizae 1-20 part.
The weight portion of each crude drug of described Chinese medicine composition is: 9 parts, Herba Ephedrae, 9 parts, Semen Armeniacae Amarum, 15 parts, Gypsum Fibrosum, Fructus Schisandrae Chinensis 10 parts, the Radix Paeoniae Alba 6 parts, Herba Asari 6 parts, the Rhizoma Pinelliae 10 parts, Radix Platycodonis 12 parts, Radix Asteris 10 parts, 6 parts, Radix Glycyrrhizae.
The oral liquor of the medicine for the treatment of cough with asthma, concrete steps are as follows:
A, crude drug process, clean Herba Ephedrae, Semen Armeniacae Amarum, Fructus Schisandrae Chinensis, the Radix Paeoniae Alba, Herba Asari, the Rhizoma Pinelliae, Radix Platycodonis, Radix Asteris, Radix Glycyrrhizae, dry, reprocess in flakes or section;
B, lixiviate, add decoction pot by the crude drug of step a process and Gypsum Fibrosum and carry out lixiviate, obtain medicine stock solution;
C, purification, carry out purified treatment by step b medicine stock solution through microfilter;
D, concentrated, the medicinal liquid after being purified by step c is condensed into concentrated medicament through backflow, and concentrating degree is to daily measuring 30-60ml;
E, subpackage sterilizing, by loading in sterile chamber after sealing after the concentrated medicament of steps d heating antiseptic, adopt flowing steam method to carry out sterilization treatment.
The lixiviate of described step b, extraction time crude drug and Gypsum Fibrosum being added decoction pot is 1-2 hour, decocts the medicine stock solution of filtering after 2-3 time and merging.
In the present invention, the pharmacological property of each raw material is as follows:
Herba Ephedrae: pungent, micro-hardship, temperature.Return lung, urinary bladder channel.Effect: diaphoresis cold expelling, depressed lung-energy dispersing, inducing diuresis to remove edema.Loose carbuncle of yin nature, eliminating mass knot is used for anemofrigid cold, uncomfortable in chestly breathes with cough, edema due to wind pathogen edema; Bronchial asthma, antipyreticly relievings asthma, diaphoresis, diuresis.
Semen Armeniacae Amarum: slightly warm in nature, bitter in the mouth.Return lung, large intestine channel.Effect: Semen Armeniacae Amarum energy relieving cough and asthma, loosening bowel to relieve constipation, can treat the diseases such as pneumonopathy, cough with asthma and cough.Have moist, have certain lung moistening tonifying the lung effect.Antiinflammatory, analgesia, antitumor, effect for reducing blood fat.
Gypsum Fibrosum: acrid in the mouth, sweet, Great Cold.Attach to the lung and stomach meridians.Effect: dispelling wind and heat pathogens: for anemopyretic cold and conjunctival congestion and swelling pain, liver heat removing and eyesight improving: for wind-fire order disease.Clearing away lung-heat and moistening for dryness: for lung-heat type cough: this product bitter cold eliminating heat from the lung, sweet cold tonifying YIN, cool lung moistening is dry, therefore can be used for dryness-heat impairing the lung, the few expectorant of dry cough.
Fructus Schisandrae Chinensis: sweet in the mouth, acid, warm in nature.Effect: Fructus Schisandrae Chinensis has the function of protection human five internal organs (heart, liver, spleen, lung, kidney), energy supplementing QI for promoting the production of body fluid, the kidney invigorating is nourished heart, and restrains astringent or styptic treatment for spontaneous sweating.For deficiency of vital energy Tianjin wound, the tired hyperhidrosis of body, cardiopalmus of losing heart; Breathing with cough caused by insufficiency of lung-QI or deficiency of both the lung and kidney, or breath with cough with the passing of time, lung qi consumption wound; Insufficiency of heart-YIN, severe palpitation, insomnia forgetfulness; Instability of kidney QI, seminal emission, frequent micturition, or asthenia of both the spleen and kidney, incessant chronic diarrhea.Strengthen body immunity and build up one's resistance to disease, accelerate to restore after being ill, recover because of long-time tired and consume energy, strengthen muscular activity when moving.
The Radix Paeoniae Alba: bitter in the mouth, flat.Return liver, spleen channel.Nourishing blood to suppress the hyperactive liver, pain relieving in slow, yin fluid astringing receives antiperspirant.Control the breast abdomen pain over the hypochondriac region, dysentery is suffered from abdominal pain, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.Suitable: people's breast abdomen pain over the hypochondriac region of the blood deficiency deficiency of YIN, pain in the hepatic region, cholecystitis gallstones pain person should eat; Dysentery is suffered from abdominal pain, and women's menalgia person should eat; Spontaneous perspiration easy antiperspirant night sweat person should eat; Sural spasm, spasm of the limbs pain, uneasy lower limb syndrome patients should eat; Coordinate with alleviating various breast abdomen and limbs pain with Radix Glycyrrhizae.
Herba Asari: nature and flavor are pungent, temperature.GUIXIN, lung, kidney channel.Effect: dispel the wind, cold expelling, row water, has one's ideas straightened out.Control air-cooled headache, nasal sinusitis, toothache, phlegm retention cough with dyspnea, rheumatic arthralgia; Dispersing wind-cold: for the headache caused by anemofrigid cold or wind and cold; Antalgic: the muscle arthralgia entering network for cold-evil; Warming for resolving cold-phlegm: stop up the chronic bronchitis of containing for rare expectorant; Lung key should be led to: for rhinitis, sinusitis.
The Rhizoma Pinelliae: acrid in the mouth, warm in nature.Return spleen, stomach, lung meridian.Effect: antitussive effect, drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass, feeling of oppression and fullness in the chest and epigastrium headache is dizzy; Uneasy sleeping at night; Gall subcutaneous nodule; Swollen ulcer drug.
Radix Platycodonis: bitter in the mouth, pungent, slightly warm in nature.Enter lung meridian.Lung qi dispersing, sore-throat relieving, eliminate the phlegm, evacuation of pus, antiasthmatic effect; Regulate the flow of vital energy, invigorate blood circulation, help digestion, sedative action, have blood sugar lowering, the effect of anti-peptic ulcer, antiinflammatory and immunological enhancement.
Radix Asteris: acrid in the mouth, sweet, bitter, tepor.Return lung meridian.Effect: nourishing the lung to keep the adverse QI downward, stopping coughing and removing phlegm.Breath with cough for abundant expectoration, new chronic cough breathe heavily and cough, chronic cough hemoptysis.Pungently can enter lung, bitter can sending down the abnormal ascending QI, therefore control cough with asthma and cough with dyspnea, phlegm dyspnea.
Radix Glycyrrhizae: property is put down, and sweet in the mouth, returns 12 warps.Effect: detoxify, eliminate the phlegm, pain relieving, spasmolytic is so that the pharmacological action such as anticancer.In the traditional Chinese medical science, Radix Glycyrrhizae invigorating the spleen and replenishing QI, grows and coughs lung moistening, and emergency is detoxified, and is in harmonious proportion hundred medicines, and spleen and stomach function goes down, and large loose stool is thin, weak heating and cough with asthma and cough, cardiopalmus etc.
In the present invention, Herba Ephedrae, Semen Armeniacae Amarum, Radix Asteris have antipyretic relievining asthma, the diseases such as treatment pneumonopathy, cough with asthma and cough; Gypsum Fibrosum, Fructus Schisandrae Chinensis, Radix Platycodonis, Radix Asteris, Radix Glycyrrhizae have clearing away lung-heat and moistening for dryness, grow and cough lung moistening; The Radix Paeoniae Alba has the breast abdomen pain over the hypochondriac region, the hepatalgia that treatment cough causes, Herba Asari treatment warming for resolving cold-phlegm: stop up the chronic bronchitis of containing for rare expectorant, should lead to lung key; Rhizoma Pinelliae antitussive effect, drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass, feeling of oppression and fullness in the chest and epigastrium headache is dizzy.Each medicine supplements and complements each other, and the mutual cooperation of various crude drug reaches medicine optimum curative effect.To sum up, the present invention, by Herba Ephedrae, Semen Armeniacae Amarum, a few taste key agents treatment of Radix Asteris cough with asthma, is also coughed lung moistening auxiliary treatment cough with asthma by other invigorating the spleen and replenishing QI, clearing away lung-heat and moistening for dryness, taste, thus is reached significant curative effect.
Oral liquor technique of the present invention is simple, and fast in absorption of human body through the oral liquid leached, dose-effect is rapid; By concentration technology, oral liquid dose reduces, and is easy to carry, preserves and takes; Oral liquid finished product, through sterilization treatment, packs, steady quality, not perishable; Oral liquid can be produced in enormous quantities, removes the trouble that consumer does it yourself to make from, taking convenience.
The present invention in clinical case 100 example, total effective rate 100%, cure rate 95%.
The present invention treats the routine clinical observation result of morbid leukorrhea 100:
1. clinical data: age 15-50 year.
2. administrated method: oral liquid, the morning, noon and afternoon service once, each 1 bottle, within 7 days, are a course for the treatment of.
3, therapeutic effect
(1) criterion of therapeutical effect
A. fully recover: symptom and sign disappears, do not recur after stopping using;
B. effective: symptom and sign disappears substantially.Comparatively the lighter is recurred after drug withdrawal.
C. invalid: to treat three months with clinical symptoms without improver.
(2) result: 95 examples of fully recovering (accounting for 95%), effective 5 examples (accounting for 5%), total effective rate 100%.
Detailed description of the invention
embodiment 1:
The medicine for the treatment of cough with asthma, this Chinese medicine composition is made up of the crude drug of following weight portion: Herba Ephedrae 1-20 part, Semen Armeniacae Amarum 1-20 part, Gypsum Fibrosum 10-30 part, Fructus Schisandrae Chinensis 1-30 part, Radix Paeoniae Alba 1-20 part, Herba Asari 1-20 part, Rhizoma Pinelliae 10-30 part, Radix Platycodonis 10-40 part, Radix Asteris 1-30 part, Radix Glycyrrhizae 1-20 part.
The weight portion of each crude drug of Chinese medicine composition is: 9 parts, Herba Ephedrae, 9 parts, Semen Armeniacae Amarum, 15 parts, Gypsum Fibrosum, Fructus Schisandrae Chinensis 10 parts, the Radix Paeoniae Alba 6 parts, Herba Asari 6 parts, the Rhizoma Pinelliae 10 parts, Radix Platycodonis 12 parts, Radix Asteris 10 parts, 6 parts, Radix Glycyrrhizae.
The oral liquor of the medicine for the treatment of cough with asthma, concrete steps are as follows:
A, crude drug process, clean Herba Ephedrae, Semen Armeniacae Amarum, Fructus Schisandrae Chinensis, the Radix Paeoniae Alba, Herba Asari, the Rhizoma Pinelliae, Radix Platycodonis, Radix Asteris, Radix Glycyrrhizae, dry, reprocess in flakes or section;
B, lixiviate, add decoction pot by the crude drug of step a process and Gypsum Fibrosum and carry out lixiviate, obtain medicine stock solution;
C, purification, carry out purified treatment by step b medicine stock solution through microfilter;
D, concentrated, the medicinal liquid after being purified by step c is condensed into concentrated medicament through backflow, and concentrating degree is to daily measuring 30-60ml;
E, subpackage sterilizing, by loading in sterile chamber after sealing after the concentrated medicament of steps d heating antiseptic, adopt flowing steam method to carry out sterilization treatment.
The lixiviate of described step b, extraction time crude drug and Gypsum Fibrosum being added decoction pot is 1-2 hour, decocts the medicine stock solution of filtering after 2-3 time and merging.
embodiment 2:
The medicine for the treatment of cough with asthma, this Chinese medicine composition is made up of the crude drug of following weight portion: 10 parts, Herba Ephedrae, 10 parts, Semen Armeniacae Amarum, 20 parts, Gypsum Fibrosum, Fructus Schisandrae Chinensis 20 parts, the Radix Paeoniae Alba 10 parts, Herba Asari 10 parts, the Rhizoma Pinelliae 20 parts, Radix Platycodonis 20 parts, Radix Asteris 20 parts, 10 parts, Radix Glycyrrhizae.
The oral liquor of the medicine for the treatment of cough with asthma, concrete steps are as follows:
A, crude drug process, by 10 parts, Herba Ephedrae, 10 parts, Semen Armeniacae Amarum, 20 parts, Gypsum Fibrosum, Fructus Schisandrae Chinensis 20 parts, the Radix Paeoniae Alba 10 parts, Herba Asari 10 parts, the Rhizoma Pinelliae 20 parts, Radix Platycodonis 20 parts, Radix Asteris 20 parts, 10 parts, Radix Glycyrrhizae is cleaned, oven dry, reprocesses in flakes or section;
B, lixiviate, the crude drug of step a process and 20 parts, Gypsum Fibrosum are added decoction pot and carries out lixiviate, extraction time is 1-2 hour, decocts the medicine stock solution of filtering after 2-3 time and merging;
C, purification, carry out purified treatment by step b medicine stock solution through microfilter;
D, concentrated, the medicinal liquid after being purified by step c is condensed into concentrated medicament through backflow, and concentrating degree is to daily measuring 30ml;
E, subpackage sterilizing, by loading in sterile chamber after sealing after the concentrated medicament of steps d heating antiseptic, adopt flowing steam method to carry out sterilization treatment.
Case 1: military certain, female, 15 years old, Linzhou City of Henan Province appointed villages and small towns to appoint people from village, cough, companion's dyspnea with rapid and short breath, cardiopalmus, hypochondriac pain.Take 3 courses for the treatment of of this oral liquid, recovery from illness.
embodiment 3:
The medicine for the treatment of cough with asthma, this Chinese medicine composition is made up of the crude drug of following weight portion: 16 parts, Herba Ephedrae, 5 parts, Semen Armeniacae Amarum, 30 parts, Gypsum Fibrosum, Fructus Schisandrae Chinensis 10 parts, the Radix Paeoniae Alba 1 part, Herba Asari 10 parts, the Rhizoma Pinelliae 25 parts, Radix Platycodonis 40 parts, Radix Asteris 30 parts, 20 parts, Radix Glycyrrhizae.
The oral liquor of the medicine for the treatment of cough with asthma, concrete steps are as follows:
A, crude drug process, by 16 parts, Herba Ephedrae, 5 parts, Semen Armeniacae Amarum, Fructus Schisandrae Chinensis 10 parts, the Radix Paeoniae Alba 1 part, Herba Asari 10 parts, the Rhizoma Pinelliae 25 parts, Radix Platycodonis 40 parts, Radix Asteris 30 parts, 20 parts, Radix Glycyrrhizae is cleaned, oven dry, reprocesses in flakes or section;
B, lixiviate, the crude drug of step a process and 30 parts, Gypsum Fibrosum are added decoction pot and carries out lixiviate, extraction time is 1-2 hour, decocts the medicine stock solution of filtering after 2-3 time and merging;
C, purification, carry out purified treatment by step b medicine stock solution through microfilter;
D, concentrated, the medicinal liquid after being purified by step c is condensed into concentrated medicament through backflow, and concentrating degree is to daily measuring 30ml;
E, subpackage sterilizing, by loading in sterile chamber after sealing after the concentrated medicament of steps d heating antiseptic, adopt flowing steam method to carry out sterilization treatment.
Case 2: Zhang, man, 25 years old, Linzhou City of Henan Province appointed villages and small towns to appoint people from village, often uncomfortable in chest, pant, tachypnea, wheezing sound, itching of the throat dry cough.Take 5 courses for the treatment of of this oral liquid, recovery from illness.
embodiment 4:
The medicine for the treatment of cough with asthma, this Chinese medicine composition is made up of the crude drug of following weight portion: 1 part, Herba Ephedrae, 2 parts, Semen Armeniacae Amarum, 5 parts, Gypsum Fibrosum, Fructus Schisandrae Chinensis 4 parts, the Radix Paeoniae Alba 4 parts, Herba Asari 1 part, the Rhizoma Pinelliae 10 parts, Radix Platycodonis 10 parts, Radix Asteris 1 part, 1 part, Radix Glycyrrhizae.
The oral liquor of the medicine for the treatment of cough with asthma, concrete steps are as follows:
A, crude drug process, by 1 part, Herba Ephedrae, 2 parts, Semen Armeniacae Amarum, Fructus Schisandrae Chinensis 4 parts, the Radix Paeoniae Alba 4 parts, Herba Asari 1 part, the Rhizoma Pinelliae 10 parts, Radix Platycodonis 10 parts, Radix Asteris 1 part, 1 part, Radix Glycyrrhizae is cleaned, oven dry, reprocesses in flakes or section;
B, lixiviate, the crude drug of step a process and 5 parts, Gypsum Fibrosum are added decoction pot and carries out lixiviate, extraction time is 1.5 hours, decocts the medicine stock solution of filtering merging for 2 times afterwards;
C, purification, carry out purified treatment by step b medicine stock solution through microfilter;
D, concentrated, the medicinal liquid after being purified by step c is condensed into concentrated medicament through backflow, and concentrating degree is to daily measuring 60ml;
E, subpackage sterilizing, by loading in sterile chamber after sealing after the concentrated medicament of steps d heating antiseptic, adopt flowing steam method to carry out sterilization treatment.
Case 3: Liu, female, 25 years old, Linzhou City of Henan Province appointed villages and small towns to appoint people from village, and dyspnea, cough, expectoration, expectorant have bubble not easily expectoration in vain.Take 4 courses for the treatment of of this oral liquid, recovery from illness.
embodiment 5:
The medicine for the treatment of cough with asthma, this Chinese medicine composition is made up of the crude drug of following weight portion: 15 parts, Herba Ephedrae, 15 parts, Semen Armeniacae Amarum, 20 parts, Gypsum Fibrosum, Fructus Schisandrae Chinensis 20 parts, the Radix Paeoniae Alba 6 parts, Herba Asari 8 parts, the Rhizoma Pinelliae 30 parts, Radix Platycodonis 20 parts, Radix Asteris 20 parts, 15 parts, Radix Glycyrrhizae.
The oral liquor of the medicine for the treatment of cough with asthma, concrete steps are as follows:
A, crude drug process, by 15 parts, Herba Ephedrae, 15 parts, Semen Armeniacae Amarum, Fructus Schisandrae Chinensis 20 parts, the Radix Paeoniae Alba 6 parts, Herba Asari 8 parts, the Rhizoma Pinelliae 30 parts, Radix Platycodonis 20 parts, Radix Asteris 20 parts, 15 parts, Radix Glycyrrhizae is cleaned, oven dry, reprocesses in flakes or section;
B, lixiviate, the crude drug of step a process and 20 parts, Gypsum Fibrosum are added decoction pot and carries out lixiviate, extraction time is 2 hours, decocts the medicine stock solution of filtering merging for 3 times afterwards;
C, purification, carry out purified treatment by step b medicine stock solution through microfilter;
D, concentrated, the medicinal liquid after being purified by step c is condensed into concentrated medicament through backflow, and concentrating degree is to daily measuring 45ml;
E, subpackage sterilizing, by loading in sterile chamber after sealing after the concentrated medicament of steps d heating antiseptic, adopt flowing steam method to carry out sterilization treatment.
Case 4: Wang, female, 37 years old, Linzhou City of Henan Province appointed villages and small towns to appoint people from village, cough, expectoration, expectorant have in vain bubble not easily expectoration and show effect in the majority, serious in the second half of the night time can cyanotic lips, whole body cold sweat.Take 4 courses for the treatment of of this oral liquid, recovery from illness.
embodiment 6:
The medicine for the treatment of cough with asthma, this Chinese medicine composition is made up of the crude drug of following weight portion: 20 parts, Herba Ephedrae, 18 parts, Semen Armeniacae Amarum, 10 parts, Gypsum Fibrosum, Fructus Schisandrae Chinensis 30 parts, the Radix Paeoniae Alba 20 parts, Herba Asari 18 parts, the Rhizoma Pinelliae 20 parts, Radix Platycodonis 30 parts, Radix Asteris 30 parts, 15 parts, Radix Glycyrrhizae.
The oral liquor of the medicine for the treatment of cough with asthma, concrete steps are as follows:
A, crude drug process, by 20 parts, Herba Ephedrae, 18 parts, Semen Armeniacae Amarum, Fructus Schisandrae Chinensis 30 parts, the Radix Paeoniae Alba 20 parts, Herba Asari 18 parts, the Rhizoma Pinelliae 20 parts, Radix Platycodonis 30 parts, Radix Asteris 30 parts, 15 parts, Radix Glycyrrhizae is cleaned, oven dry, reprocesses in flakes or section;
B, lixiviate, the crude drug of step a process and 10 parts, Gypsum Fibrosum are added decoction pot and carries out lixiviate, extraction time is 1 hour, decocts the medicine stock solution of filtering merging for 3 times afterwards;
C, purification, carry out purified treatment by step b medicine stock solution through microfilter;
D, concentrated, the medicinal liquid after being purified by step c is condensed into concentrated medicament through backflow, and concentrating degree is to daily measuring 60ml;
E, subpackage sterilizing, by loading in sterile chamber after sealing after the concentrated medicament of steps d heating antiseptic, adopt flowing steam method to carry out sterilization treatment.
Case 5: go into business certain, man, 50 years old, Linzhou City of Henan Province appointed villages and small towns to appoint people from village, and dyspnea, expectoration are serious, whole body cold sweat, anxious, serious agitation, face foot edema.Take 6 courses for the treatment of of this oral liquid, recovery from illness.
Claims (4)
1. treat the medicine of cough with asthma, it is characterized in that: this Chinese medicine composition is made up of the crude drug of following weight portion: Herba Ephedrae 1-20 part, Semen Armeniacae Amarum 1-20 part, Gypsum Fibrosum 10-30 part, Fructus Schisandrae Chinensis 1-30 part, Radix Paeoniae Alba 1-20 part, Herba Asari 1-20 part, Rhizoma Pinelliae 10-30 part, Radix Platycodonis 10-40 part, Radix Asteris 1-30 part, Radix Glycyrrhizae 1-20 part.
2. the medicine for the treatment of cough with asthma according to claim 1, is characterized in that: the weight portion of each crude drug of described Chinese medicine composition is: 9 parts, Herba Ephedrae, 9 parts, Semen Armeniacae Amarum, 15 parts, Gypsum Fibrosum, Fructus Schisandrae Chinensis 10 parts, the Radix Paeoniae Alba 6 parts, Herba Asari 6 parts, the Rhizoma Pinelliae 10 parts, Radix Platycodonis 12 parts, Radix Asteris 10 parts, 6 parts, Radix Glycyrrhizae.
3. the oral liquor of the medicine for the treatment of cough with asthma according to claim 1 and 2, is characterized in that: concrete steps are as follows:
A, crude drug process, clean Herba Ephedrae, Semen Armeniacae Amarum, Fructus Schisandrae Chinensis, the Radix Paeoniae Alba, Herba Asari, the Rhizoma Pinelliae, Radix Platycodonis, Radix Asteris, Radix Glycyrrhizae, dry, reprocess in flakes or section;
B, lixiviate, add decoction pot by the crude drug of step a process and Gypsum Fibrosum and carry out lixiviate, obtain medicine stock solution;
C, purification, carry out purified treatment by step b medicine stock solution through microfilter;
D, concentrated, the medicinal liquid after being purified by step c is condensed into concentrated medicament through backflow, and concentrating degree is to daily measuring 30-60ml;
E, subpackage sterilizing, by loading in sterile chamber after sealing after the concentrated medicament of steps d heating antiseptic, adopt flowing steam method to carry out sterilization treatment.
4. the oral liquor of the medicine for the treatment of cough with asthma according to claim 3, is characterized in that: the lixiviate of described step b, and extraction time crude drug and Gypsum Fibrosum being added decoction pot is 1-2 hour, decocts the medicine stock solution of filtering after 2-3 time and merging.
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| CN201310561862.7A CN104623148A (en) | 2013-11-13 | 2013-11-13 | Medicament for treating cough and asthma and preparation method of oral liquid thereof |
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| CN201310561862.7A CN104623148A (en) | 2013-11-13 | 2013-11-13 | Medicament for treating cough and asthma and preparation method of oral liquid thereof |
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| CN104623148A true CN104623148A (en) | 2015-05-20 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106266871A (en) * | 2016-09-14 | 2017-01-04 | 张元鸿 | A kind of for compound medicine treating cough with asthma and preparation method thereof |
| CN107281454A (en) * | 2017-06-23 | 2017-10-24 | 广西中医药大学第附属医院 | One kind pharynx, which is itched, coughs mixture and preparation method thereof |
| CN107281348A (en) * | 2017-05-27 | 2017-10-24 | 江西合盈生物科技有限公司 | A kind of thousand mesh Chinese medicine preparations and preparation method, quality standard for being used to prevent and treat livestock and poultry cough and asthma syndrome |
-
2013
- 2013-11-13 CN CN201310561862.7A patent/CN104623148A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106266871A (en) * | 2016-09-14 | 2017-01-04 | 张元鸿 | A kind of for compound medicine treating cough with asthma and preparation method thereof |
| CN107281348A (en) * | 2017-05-27 | 2017-10-24 | 江西合盈生物科技有限公司 | A kind of thousand mesh Chinese medicine preparations and preparation method, quality standard for being used to prevent and treat livestock and poultry cough and asthma syndrome |
| CN107281454A (en) * | 2017-06-23 | 2017-10-24 | 广西中医药大学第附属医院 | One kind pharynx, which is itched, coughs mixture and preparation method thereof |
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Application publication date: 20150520 |