CN107115515A - A kind of Hyperglycemic health care Chinese medicine composition and preparation method thereof - Google Patents
A kind of Hyperglycemic health care Chinese medicine composition and preparation method thereof Download PDFInfo
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Abstract
The invention provides a kind of Hyperglycemic health care Chinese medicine composition and preparation method thereof.The Hyperglycemic health care Chinese medicine composition, is made up of the raw material of following parts by weight：5~40 parts of 1~10 part of blue or green money willow, 1~10 part of Momordica grosvenori, 3~20 parts of STEVIA REBAUDIANA, 1~10 part of dendrobium candidum, 1~10 part of roxburgh anoectochilus terminal bud, 3~20 parts of Cordyceps militaris, 5~40 parts of the root of kudzu vine, 1~40 part of rhizoma zingiberis, 1~20 part of honeysuckle, 3~30 parts of dried orange peel and radix glycyrrhizae.The Hyperglycemic health care Chinese medicine composition that the present invention is provided has nourishing Yin and promoting production of body fluid, righting QI invigorating, effect of strengthening the spleen and stomach, safety non-toxic can be while balance adjustment yin-Yang, human body is set to reach yin and yang in equilibrium, immunity is improved, and recovers organism physiology metabolism, promotes metabolism of the body to material to utilize and the excretion to metabolic waste, recover body normal function, keep fit.
Description
Technical field
The present invention relates to Chinese medicine health-care field, more particularly to a kind of Hyperglycemic health care Chinese medicine composition and its preparation side
Method.
Background technology
The traditional Chinese medical science thinks that the cause of diabetes is due to lack motion, or disorder of emotion again when human diet is excessive, or labor is intended to
Excessively, nutrient metabolism can be caused abnormal（The deficiency of yang）, metabolic waste discharge is hindered, phlegm wet is formed.The continuous accumulation of phlegm wet, it is right
Cell produces toxic action, can reduce Utilization ability of the cell to nutriment, show as the ability of cell disintegration nutriment
Reduction, body energy is not enough, i.e. the deficiency of yang.The deficiency of yang can make body cell store nutriment, repair the function reduction of body, and then
The deficiency of Yin can also be caused, can be shown as fire excess from yin deficiency, scorching from head to foot.The deficiency of Yin symptom i.e. as caused by the deficiency of yang.
Diabetes are one of modern society's usually said " three high diseases ", the improvement of modern society's life condition and work
Make the quickening of rhythm with so that people's amount of exercise is few and takes in nutrition excess, and long-term bad habits and customs make the metabolism of body
Metabolic disorder occurs for system, so as to " three high " disease occur, these metabolic disorder disease quantity it is annual all sharply increasing and
Gradually rejuvenation（40 years old or so）, these metabolic disorder diseases, Western medicine is relief of symptoms, is not fundamentally to solve disease
Cause.Such case causes the attention of modern people, it is contemplated that can nurse one's health human physiological functions, make body metabolism system extensive
The health products or Chinese medicine composition of multiple eubolism function.
The content of the invention
In view of this, the purpose of the present invention is that in view of the shortcomings of the prior art, there is provided a kind of property for regulation blood glucose balance
The Hyperglycemic health care Chinese medicine composition of moderate notoxic side effect.
To reach above-mentioned purpose, the present invention uses following technical scheme：
A kind of Hyperglycemic health care Chinese medicine composition, is made up of the raw material of following parts by weight：1~10 part of blue or green money willow, Momordica grosvenori 1~10
Part, 3~20 parts of STEVIA REBAUDIANA, 1~10 part of dendrobium candidum, 1~10 part of roxburgh anoectochilus terminal bud, 3~20 parts of Cordyceps militaris, 5~40 parts of the root of kudzu vine, rhizoma zingiberis
5~40 parts of 1~40 part, 1~20 part of honeysuckle, 3~30 parts of dried orange peel and radix glycyrrhizae.
Further, it is made up of the raw material of following parts by weight：2~5 parts of blue or green money willow, 2~10 parts of Momordica grosvenori, STEVIA REBAUDIANA 3~
10 parts, 1~5 part of dendrobium candidum, 1~5 part of roxburgh anoectochilus terminal bud, 5~10 parts of Cordyceps militaris, 6~20 parts of the root of kudzu vine, 5~20 parts of rhizoma zingiberis, honeysuckle
5~20 parts of 3~10 parts, 3~10 parts of dried orange peel and radix glycyrrhizae.
Present invention also offers the preparation method of above-mentioned health-care Chinese medicinal composition, comprise the following steps：
1）By the composition material after 50 DEG C~80 DEG C bakee, coarse crushing obtains coarse powder；
2）By step 1）Gained coarse powder adds the solvent of 2-3 times of parts by weight, and 70 DEG C~80 DEG C are extracted, filtering, filtrate concentration,
Dry the blood sugar reducing health Chinese medicine composition active ingredient；The solvent is water or water-ethanol mixed liquor；
3）By step 2）Gained effective ingredient adds auxiliary material, and required formulation is made.
Further, step 1）The coarse crushing is：80 mesh sieves are crushed or crushed with Universalpulverizer to standard machinery.
Further, step 2）The method of the extraction is：By stirring solvent of water, extraction is extracted or ultrasonic and circulated extraction.
Further, step 2）The method of the extraction is：Using water-ethanol it is any extracted than mixed liquor to be solvent impregnated or
Seepage pressure effects.
Further, step 2）It is described to be filtered into：Filtered using plate-frame filtering sizing of equipment, the filter after being filtered through 300 mesh
Liquid, 40 DEG C of -50 DEG C of vacuum concentrations, concentrate is crushed again after 50 DEG C~70 DEG C dryings of vacuum.
Further, step 3）The formulation is granule, tablet, pill, capsule, oral liquid, powder, decoction or cream
Agent.
Another object of the present invention is to Hyperglycemic health care Chinese medicine composition answering in hypoglycemic and blood-pressure drug
With.
The pharmacology of the present invention is as follows：
Blue or green money willow：It is sweet, it is mild-natured.With clearing heat and detoxicating, activity of islet cells is activated, promotes glycometabolism, effect of lowering blood sugar.
Momordica grosvenori：It is sweet, it is cool in nature, moisten the lung and relieve the cough, promote the production of body fluid to quench thirst, it is adaptable to lung heat or xeropulmonary cough, pertussis and heat
Hot fluid deficiency and thirsty, the effect also relaxed bowel.
STEVIA REBAUDIANA：It is sweet, cool in nature, nourishing Yin and promoting production of body fluid, reduction blood fat, hypoglycemic, regulation blood pressure, softening blood vessel, promotion pancreas,
Spleen and stomach function and clearing heat and detoxicating.
Dendrobium candidum：It is sweet, cold nature.Promote the production of body fluid nourishing the stomach；Nourishing Yin and clearing heat；Moistening lung kidney-nourishing；The strong waist of improving eyesight.Gas under eliminating impediment, is mended
The five internal organs consumptive disease wins thin, strong the moon strengthening the essence.Never sufficient, flat stomach gas, long muscle, by skin heat symptoms caused by an exopathgen miliaria gas, pin in long term usage, thick stomach, benefit
The cold numbness of knee pain is weak, determines intelligence except frightened, macrobiosis of making light of one's life by commiting suicide.
Roxburgh anoectochilus terminal bud：Bitter, it is cool in nature.Clearing heat and cooling blood, expelling wind and removing dampness, cardiac stimulant diuresis is reinforced the kidney, the effects such as soothing the liver.Cure mainly：Cough up
Blood, bronchitis, ephritis, cystitis, pneumonia, diabetes, rheumatism, the disease such as venomous snake bite.
Cordyceps militaris：It is sweet, it is mild-natured.With strengthening the spleen and replenishing qi, kidney tonifying benefit lung mends marrow, the effect of relieving cough and reducing sputum, both tonifying lung was cloudy
And kidney-replenishing.
Honeysuckle：Bitter, it is cold in nature.The effect of being become silted up with clearing heat and detoxicating, cool blood, long term usage is made light of one's life by commiting suicide, promoted longevity.
Rhizoma zingiberis：Sweet, property is pungent, temperature.With warm stomach preventing or arresting vomiting, the effects such as invigorating the spleen to clear away damp pathogen.For deficiency-cold in spleen and stomach, nausea and vomiting,
The ice-cold disease such as inverse of fainting of four limbs.
The root of kudzu vine：Sweet, pungent, cool in nature, the root of kudzu vine has inducing diaphoresis to bring down a fever, promoted the production of body fluid to quench thirst, the function of antidiarrheal, also with hypoglycemic, blood
Fat, anti-inflammatory etc. are acted on, and can improve the Xiang Qiang of hypertensive diabetes patient, dizziness, headache.
Dried orange peel：Pungent, hardship, it is warm-natured.There is qi-regulating with, eliminating dampness and eliminating phlegm, effect of sharp water defaecation；Cure mainly incoordination between the spleen and the stomach, gastral cavity
Abdominal distention and pain, do not feel like eating vomits hiccup；Phlegm-damp obstructing lung, coughing with a lot of sputum, full vexed, the vertigo of chest diaphragm；Oedema, difficult urination, greatly
Constipation knot.
Radix glycyrrhizae：It is sweet, it is mild-natured.It is clearing heat and detoxicating, moisten the lung and relieve the cough, invigorate the spleen and benefit qi.Alleviate drug toxicity, strong, coordinating the drug actions of a prescription
Property.
The beneficial effects of the invention are as follows：
The Hyperglycemic health care Chinese medicine composition of the present invention has nourishing Yin and promoting production of body fluid, righting QI invigorating, effect of strengthening the spleen and stomach, safe nothing
Poison, can be while balance adjustment yin-Yang, makes human body reach yin and yang in equilibrium, and immunity is improved, and recovers organism physiology metabolism,
Promote metabolism of the body to material to utilize and the excretion to metabolic waste, recover body normal function, keep fit.
The invention provides the preparation method of the Hyperglycemic health care Chinese medicine composition, it is crushed with traditional Chinese medicine, extracted
Technique is combined with the medicinal property of the present invention, ensure that traditional Chinese medicine ingredients are not lost in, are not destroyed on the premise of effective extract,
Herbal nature feature has been effectively ensured.
Hyperglycemic health care Chinese medicine composition mild in medicine property that the present invention is provided and, can rationally be taken with other hypoglycemic antihypertensive drugs
Match somebody with somebody, reach the effect of synergy each other.
Embodiment
Technical scheme is discussed in detail below in conjunction with embodiment.
Embodiment 1
A kind of Hyperglycemic health care Chinese medicine composition, is made up of the raw material of following parts by weight：1 part of blue or green money willow, 1 part of Momordica grosvenori, sweetleaf
3 parts of chrysanthemum, 1 part of dendrobium candidum, 1 part of roxburgh anoectochilus terminal bud, 3 parts of Cordyceps militaris, 5 parts of the root of kudzu vine, 1 part of rhizoma zingiberis, 1 part of honeysuckle, 3 parts of dried orange peel and radix glycyrrhizae
5 parts.
Its preparation method, comprises the following steps：
1）By the composition material after 50 DEG C bakee, 80 mesh sieves were crushed with standard machinery, coarse powder is obtained；
2）By step 1）Gained coarse powder adds the water of 2 times of parts by weight, and 70 DEG C of stirring and leachings are extracted, and use plate-frame filtering sizing of equipment
Filtering, the filtrate after being filtered through 300 mesh, 40 DEG C of vacuum concentrations, concentrate is crushed again after 50 DEG C of dryings of vacuum, obtains blood sugar reducing health
Chinese medicine composition active ingredient；
3）By step 2）Gained effective ingredient adds auxiliary material, and granule is made.
Embodiment 2
A kind of Hyperglycemic health care Chinese medicine composition, is made up of the raw material of following parts by weight：10 parts of blue or green money willow, 10 parts of Momordica grosvenori, sweet tea
20 parts of leaf chrysanthemum, 10 parts of dendrobium candidum, 10 parts of roxburgh anoectochilus terminal bud, 20 parts of Cordyceps militaris, 40 parts of the root of kudzu vine, 40 parts of rhizoma zingiberis, 20 parts of honeysuckle, dried orange peel
30 parts and 40 parts of radix glycyrrhizae.
Its preparation method, comprises the following steps：
1）By the composition material after 80 DEG C bakee, 80 mesh sieves were crushed with Universalpulverizer, coarse powder is obtained；
2）By step 1）Gained coarse powder adds the water of 3 times of parts by weight, and 80 DEG C of ultrasonic and circulated extractions are extracted, and use plate-frame filtering equipment
Classified filtering, the filtrate after being filtered through 300 mesh, 50 DEG C of vacuum concentrations, concentrate is crushed again after 70 DEG C of dryings of vacuum, obtains described
Blood sugar reducing health Chinese medicine composition active ingredient；
3）By step 2）Gained effective ingredient adds auxiliary material, and tablet is made.
Embodiment 3
A kind of Hyperglycemic health care Chinese medicine composition, is made up of the raw material of following parts by weight：5 parts of blue or green money willow, 5 parts of Momordica grosvenori, sweetleaf
11 parts of chrysanthemum, 5 parts of dendrobium candidum, 6 parts of roxburgh anoectochilus terminal bud, 11 parts of Cordyceps militaris, 22 parts of the root of kudzu vine, 20 parts of rhizoma zingiberis, 10 parts of honeysuckle, 15 parts of dried orange peel
With 22 parts of radix glycyrrhizae.
Its preparation method, comprises the following steps：
1）By the composition material after 65 DEG C bakee, 80 mesh sieves were crushed with Universalpulverizer, coarse powder is obtained；
2）By step 1）Gained coarse powder adds the water-ethanol mixed liquor of 2.5 times of parts by weight, and 75 DEG C with water-ethanol arbitrarily than mixing
Liquid extracts to be solvent impregnated, is filtered using plate-frame filtering sizing of equipment, the filtrate after being filtered through 300 mesh, 45 DEG C of vacuum concentrations, dense
Contracting liquid is crushed again after 60 DEG C of dryings of vacuum, obtains the blood sugar reducing health Chinese medicine composition active ingredient；
3）By step 2）Gained effective ingredient adds auxiliary material, and pill is made.
Embodiment 4
A kind of Hyperglycemic health care Chinese medicine composition, is made up of the raw material of following parts by weight：2 parts of blue or green money willow, 2 parts of Momordica grosvenori, sweetleaf
6 parts of chrysanthemum, 1 part of dendrobium candidum, 1 part of roxburgh anoectochilus terminal bud, 10 parts of Cordyceps militaris, 6 parts of the root of kudzu vine, 8 parts of rhizoma zingiberis, 3 parts of honeysuckle, 5 parts of dried orange peel and sweet
5 parts of grass.
Its preparation method, comprises the following steps：
1）By the composition material after 60 DEG C bakee, standard machinery is crushed, and obtains coarse powder；
2）By step 1）The water-ethanol that gained coarse powder adds 2 times of parts by weight is any than mixed liquor, and 70 DEG C are arbitrarily compared with water-ethanol
Mixed liquor is solvent seepage pressure effects, is filtered using plate-frame filtering sizing of equipment, the filtrate after being filtered through 300 mesh, and 40 DEG C -50 DEG C true
Sky concentration, concentrate is crushed again after 50 DEG C~70 DEG C dryings of vacuum, obtains the blood sugar reducing health Chinese medicine composition active ingredient；
3）By step 2）Gained effective ingredient adds auxiliary material, and capsule or oral liquid is made.
Embodiment 5
A kind of Hyperglycemic health care Chinese medicine composition, is made up of the raw material of following parts by weight：4 parts of blue or green money willow, 1 part of Momordica grosvenori, sweetleaf
3 parts of chrysanthemum, 5 parts of dendrobium candidum, 3 parts of roxburgh anoectochilus terminal bud, 5 parts of Cordyceps militaris, 10 parts of the root of kudzu vine, 3 parts of rhizoma zingiberis, 5 parts of honeysuckle, 3 parts of dried orange peel and sweet
8 parts of grass.
Its preparation method, comprises the following steps：
1）By the composition material after 55 DEG C bakee, 80 mesh sieves were crushed with Universalpulverizer, coarse powder is obtained；
2）By step 1）Gained coarse powder adds the water of 3 times of parts by weight, and 80 DEG C of progress ultrasonic and circulated extractions use plate-frame filtering equipment
Classified filtering, the filtrate after being filtered through 300 mesh, 45 DEG C of vacuum concentrations, concentrate is crushed again after 60 DEG C of dryings of vacuum, obtains described
Blood sugar reducing health Chinese medicine composition active ingredient；
3）By step 2）Gained effective ingredient adds auxiliary material, and decoction or paste is made.
Clinical typical case
Below by way of clinical case, illustrate the therapeutic effect for the Hyperglycemic health care Chinese medicine composition that the present invention is provided.
Application Example 1
Wei so-and-so, female, 65 years old, Xinyang people from Shihe District
Chemically examine fasting blood-glucose 150mg/dL, noon postprandial blood sugar 190150mg/dL.The big loose stool of readme nearly 5 years, soreness and weakness of waist and knees, entirely
Body is weak, thirsty many drinks nearly 3 years.Take " Jiangtangwan pill "（Every 0.25mg containing glibenclamide）1 year, illness had no improvement.
Start on April 10th, 2016 to take blood sugar reducing health combined extracts of the invention（Tablet, 5 pieces/times, 3 times a day,
Every 0.4g containing extract）.Just taking first month still normally takes " Jiangtangwan pill ", and second month is gradually cut " Jiangtangwan pill ".
On May 12nd, 2016 pays a return visit, and takes the blood sugar reducing health combined extracts of the present invention（Tablet, 5 pieces/times, 3 times a day, every containing carrying
Take thing 0.4g）2 months, patient's readme loose stool was good, 1 time a day, and soreness and weakness of waist and knees, malaise symptom is clearly better, thirsty many
Number of times is drunk to reduce.On June 10th, 2016 pays a return visit, and takes 3 months, chemically examines fasting blood-glucose 110mg/dL, noon postprandial blood sugar 120mg/
dL.Inform that patient continues to take.
Application Example 2
Liu so-and-so, man, 55 years old, Xinyang south gulf landscape directorial area people
Patient, which was recalled from spring in 2015, begins with many food diuresis of many drinks, starts to become thin during winter in 2015, soreness of waist fatigue and weak.
Hospital's urine routine test：Urine proteins（-）, glucose in urine（++）, fasting blood-glucose 10.75mmol/L.It is diagnosed as diabetes B.
Western medicine antidiabetic drug about six months are taken, blood glucose can be controlled effectively during medication, but soreness of waist fatigue and weak does not have
Alleviate, and be discontinued 2 days after blood glucose it is also high.Start on May 15th, 2016 to take blood sugar reducing health combined extracts of the invention（Piece
Agent, 8 pieces/times, 3 times a day, every 0.4g containing extract）.Just taking first month still normally takes Western medicine hypoglycemic medicine, second
The moon gradually cuts Western medicine.August is paid a return visit on the 12nd within 2016, takes the blood sugar reducing health combined extracts of the present invention（Tablet, 8 pieces/times,
3 times a day, every 0.4g containing extract）3 months, patient's soreness and weakness of waist and knees, malaise symptom was clearly better, thirsty many drink number of times
Reduce, body weight is in increase, fasting blood-glucose 7.85mmol/L.Inform that patient continues to take the blood sugar reducing health combination of the present invention after return visit
Extract, it is possible to reduce dose（Tablet, 5 pieces/times, 3 times a day, every 0.4g containing extract）.
Finally illustrate, the above embodiments are merely illustrative of the technical solutions of the present invention and it is unrestricted, this area is common
Other modifications or equivalent substitution that technical staff is made to technical scheme, without departing from technical solution of the present invention
Spirit and scope, all should cover among scope of the presently claimed invention.
Claims (9)
1. a kind of Hyperglycemic health care Chinese medicine composition, it is characterised in that be made up of the raw material of following parts by weight：Blue or green money willow 1~10
Part, 1~10 part of Momordica grosvenori, 3~20 parts of STEVIA REBAUDIANA, 1~10 part of dendrobium candidum, 1~10 part of roxburgh anoectochilus terminal bud, 3~20 parts of Cordyceps militaris, Pueraria lobota
5~40 parts of 5~40 parts of root, 1~40 part of rhizoma zingiberis, 1~20 part of honeysuckle, 3~30 parts of dried orange peel and radix glycyrrhizae.
2. Hyperglycemic health care Chinese medicine composition according to claim 1, it is characterised in that by the raw material group of following parts by weight
Into：2~5 parts of blue or green money willow, 2~10 parts of Momordica grosvenori, 3~10 parts of STEVIA REBAUDIANA, 1~5 part of dendrobium candidum, 1~5 part of roxburgh anoectochilus terminal bud, pupa worm
5~20 parts of 5~10 parts of grass, 6~20 parts of the root of kudzu vine, 5~20 parts of rhizoma zingiberis, 3~10 parts of honeysuckle, 3~10 parts of dried orange peel and radix glycyrrhizae.
3. a kind of preparation method of Hyperglycemic health care Chinese medicine composition according to claim 1 or claim 2, it is characterised in that including
Following steps：
1）By the composition material after 50 DEG C~80 DEG C bakee, coarse crushing obtains coarse powder；
2）By step 1）Gained coarse powder adds the solvent of 2-3 times of parts by weight, and 70 DEG C~80 DEG C are extracted, filtering, filtrate concentration,
Dry the blood sugar reducing health Chinese medicine composition active ingredient；The solvent is water or water-ethanol mixed liquor；
3）By step 2）Gained effective ingredient adds auxiliary material, and required formulation is made.
4. the preparation method of Hyperglycemic health care Chinese medicine composition according to claim 3, it is characterised in that step 1）It is described
Coarse crushing is：80 mesh sieves are crushed or crushed with Universalpulverizer to standard machinery.
5. the preparation method of Hyperglycemic health care Chinese medicine composition according to claim 3, it is characterised in that step 2）It is described
The method of extraction is：By stirring solvent of water, extraction is extracted or ultrasonic and circulated extraction.
6. the preparation method of Hyperglycemic health care Chinese medicine composition according to claim 3, it is characterised in that step 2）It is described
The method of extraction is：Using water-ethanol it is any than mixed liquor as solvent impregnated extraction or seepage pressure effects.
7. the preparation method of Hyperglycemic health care Chinese medicine composition according to claim 3, it is characterised in that step 2）It is described
It is filtered into：Filtered using plate-frame filtering sizing of equipment, the filtrate after being filtered through 300 mesh, 40 DEG C of -50 DEG C of vacuum concentrations, concentrate
Crushed again after 50 DEG C~70 DEG C dryings of vacuum.
8. the preparation method according to claim any one of 3-7, it is characterised in that step 3）The formulation be granule,
Tablet, pill, capsule, oral liquid, powder, decoction or paste.
9. application of the Hyperglycemic health care Chinese medicine composition in hypoglycemic and blood-pressure drug.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112439043A (en) * | 2019-09-02 | 2021-03-05 | 邵东县锋正堂生物科技有限公司 | Pure Chinese patent medicine blood pressure reducing combined tablet for promoting cerebral blood supply |
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| CN102462834A (en) * | 2010-11-17 | 2012-05-23 | 仝小林 | Medicinal composition for controlling blood sugar of diabetic |
| CN103417683A (en) * | 2012-05-20 | 2013-12-04 | 苏州法莫生物技术有限公司 | Health food capable of reducing blood sugar |
| CN106075338A (en) * | 2016-07-06 | 2016-11-09 | 湖南净初社区健康科技有限公司 | Health-care Chinese medicinal composition and its preparation method and application |
| CN106176918A (en) * | 2015-04-29 | 2016-12-07 | 无限极（中国）有限公司 | A kind of Hyperglycemic health care compositions comprising leaf of Cyclocarya paliurus Iljinskaja and Radix Puerariae |
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Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102462834A (en) * | 2010-11-17 | 2012-05-23 | 仝小林 | Medicinal composition for controlling blood sugar of diabetic |
| CN103417683A (en) * | 2012-05-20 | 2013-12-04 | 苏州法莫生物技术有限公司 | Health food capable of reducing blood sugar |
| CN106176918A (en) * | 2015-04-29 | 2016-12-07 | 无限极（中国）有限公司 | A kind of Hyperglycemic health care compositions comprising leaf of Cyclocarya paliurus Iljinskaja and Radix Puerariae |
| CN106075338A (en) * | 2016-07-06 | 2016-11-09 | 湖南净初社区健康科技有限公司 | Health-care Chinese medicinal composition and its preparation method and application |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN112439043A (en) * | 2019-09-02 | 2021-03-05 | 邵东县锋正堂生物科技有限公司 | Pure Chinese patent medicine blood pressure reducing combined tablet for promoting cerebral blood supply |
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