CN107737280A - Chinese medicine composition for treating diabetes and its preparation method and application - Google Patents

Chinese medicine composition for treating diabetes and its preparation method and application Download PDF

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Publication number
CN107737280A
CN107737280A CN201711210319.7A CN201711210319A CN107737280A CN 107737280 A CN107737280 A CN 107737280A CN 201711210319 A CN201711210319 A CN 201711210319A CN 107737280 A CN107737280 A CN 107737280A
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parts
traditional chinese
medicinal components
medicine composition
diabetes
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周人
冯侠圣
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Shanghai Keyang Health Industry Co.,Ltd.
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Shanghai Techtrans Multi-Creation Space Management Center (limited Partnership)
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/62Nymphaeaceae (Water-lily family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/57Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/52Juglandaceae (Walnut family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • A61K36/8984Dendrobium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8994Coix (Job's tears)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/90Smilacaceae (Catbrier family), e.g. greenbrier or sarsaparilla
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH

Abstract

Present invention offer is a kind of to be used to treat Chinese medicine composition of diabetes and its preparation method and application, is related to technical field of traditional Chinese medicines.A kind of Chinese medicine composition for being used to treat diabetes, including the first traditional Chinese medicinal components and the second traditional Chinese medicinal components, are counted, the first traditional Chinese medicinal components include in parts by weight:5~15 parts of lotus seeds, 5~15 parts of smilax, 1~9 part of the membrane of a chicken's gizzard, 5~15 parts of Chinese yam, 5~15 parts of Gorgon fruit, 5~15 parts of Semen Coicis, 5~15 parts of the root of kudzu vine;Second traditional Chinese medicinal components include:5~15 parts of russule, 5~15 parts of Agricus blazei, 1~9 part of the stem of noble dendrobium, 1~9 part of mountain honeywort, 0.1~1 part of STEVIA REBAUDIANA, 1~9 part of blue or green money willow.The Chinese medicine composition auxiliary treatment diabetes, mitigate the symptom of diabetes, good drug efficacy, have no side effect.

Description

Chinese medicine composition for treating diabetes and its preparation method and application
Technical field
The present invention relates to technical field of traditional Chinese medicines, and more particularly to a kind of Chinese medicine composition and its system for being used to treat diabetes Preparation Method and application.
Background technology
Diabetes are one group of metabolic diseases characterized by hyperglycaemia.Hyperglycaemia be due to then defect of insulin secretion or Its biological agent is damaged, or both have concurrently and cause.The long-standing hyperglycaemia of diabetes, cause various tissues, particularly eye, Kidney, heart, blood vessel, the chronic lesion of nerve, dysfunction.
Sugar is exceeded in diabetic's one side blood, and sugar, required nutrition are but lacked in another aspect cell Cell is cannot be introduced into, causes diabetes.Patient's fatigue and weak with diabetes, lean body mass, easily there is skin scabies and swell, exhale Inhale, the various inflammation of uropoiesis biliary system.
The content of the invention
It is an object of the invention to provide a kind of Chinese medicine composition for being used to treat diabetes, Chinese medicine composition auxiliary is controlled Diabetes are treated, mitigates the symptom of diabetes, good drug efficacy, has no side effect.
Another object of the present invention is to provide a kind of preparation method for being used to treat the Chinese medicine composition of diabetes, the system Preparation Method is simple and easy, while maintaining drug effect, is easy to industrialized production.
Another object of the present invention is to provide a kind of preparation method for being used to treat the Chinese medicine composition of diabetes, the system Preparation Method is simple and easy, workable, can good effective component extracting, ensure drug effect.
Another object of the present invention is to provide a kind of application for being used to treat the Chinese medicine composition of diabetes.
The present invention is solved its technical problem and realized using following technical scheme.
A kind of Chinese medicine composition for being used to treat diabetes, including the first traditional Chinese medicinal components and the second traditional Chinese medicinal components, by weight Number meter,
First traditional Chinese medicinal components include:5~15 parts of lotus seeds, 5~15 parts of smilax, 1~9 part of the membrane of a chicken's gizzard, 5~15 parts of Chinese yam, 5~15 parts of Gorgon fruit, 5~15 parts of Semen Coicis, 5~15 parts of the root of kudzu vine;
Second traditional Chinese medicinal components include:5~15 parts of russule, 5~15 parts of Agricus blazei, 1~9 part of the stem of noble dendrobium, 1~9 part of mountain honeywort, sweet tea 0.1~1 part of leaf chrysanthemum, 1~9 part of blue or green money willow.
The present invention proposes a kind of preparation method for being used to treat the Chinese medicine composition of diabetes, including:Respectively by first Medicine component and the second traditional Chinese medicinal components are dry, crush.
The present invention proposes a kind of preparation method for being used to treat the Chinese medicine composition of diabetes, including:Respectively by first Medicine component and the second Chinese medicine group are decocted.
The a kind of of the embodiment of the present invention is used to treat the beneficial of the Chinese medicine composition of diabetes and its preparation method and application Effect is:
The present invention is studied with reference to modern medicines, and the balanced nutrients prescription of science is formed with reference to clinical experience, and the prescription has The effect of " reinforcing spleen and kidney, nourishing strong ", can adjust immunity of organisms, strengthen body immunity, adjust in blood and thin Blood-sugar content in born of the same parents, unnecessary sugar in blood is eliminated, promote patient to absorb sugar, by nutrition assistant interventional, Mitigate diabetes symptom, reduce blood-sugar content, there is preferable effect for treatment diabetes.
Embodiment
, below will be in the embodiment of the present invention to make the purpose, technical scheme and advantage of the embodiment of the present invention clearer Technical scheme be clearly and completely described.Unreceipted actual conditions person, builds according to normal condition or manufacturer in embodiment The condition of view is carried out.Agents useful for same or the unreceipted production firm person of instrument, it is the conventional production that can be obtained by commercially available purchase Product.
Below to a kind of Chinese medicine composition for being used to treat diabetes of the embodiment of the present invention and its preparation method and application It is specifically described.
A kind of Chinese medicine composition for being used to treat diabetes, including the first traditional Chinese medicinal components and the second traditional Chinese medicinal components, by weight Number meter,
First traditional Chinese medicinal components include:5~15 parts of lotus seeds, 5~15 parts of smilax, 1~9 part of the membrane of a chicken's gizzard, 5~15 parts of Chinese yam, 5~15 parts of Gorgon fruit, 5~15 parts of Semen Coicis, 5~15 parts of the root of kudzu vine;
Second traditional Chinese medicinal components include:5~15 parts of russule, 5~15 parts of Agricus blazei, 1~9 part of the stem of noble dendrobium, 1~9 part of mountain honeywort, sweet tea 0.1~1 part of leaf chrysanthemum, 1~9 part of blue or green money willow.
Preferably, lotus seeds can be 6 parts, 7 parts, 13 parts, 14 parts, and smilax can be 6 parts, 7 parts, 13 parts, 14 parts, in chicken Gold can be 2 parts, 8 parts, and Chinese yam can be 6 parts, 7 parts, 13 parts, 14 parts, and Gorgon fruit can be 6 parts, 7 parts, 13 parts, 14 parts, Semen Coicis It can be 6 parts, 7 parts, 13 parts, 14 parts, the root of kudzu vine can be 6 parts, 7 parts, 13 parts, 14 parts.
Preferably, russule can be 6 parts, 7 parts, 13 parts, 14 parts, and Agricus blazei can be 6 parts, 7 parts, 13 parts, 14 parts, the stem of noble dendrobium It can be 2 parts, 8 parts, mountain honeywort can be 2 parts, 8 parts, and STEVIA REBAUDIANA can be 0.9 part, and blue or green money willow can be 2 parts, 8 parts.
Further, in the present invention preferably embodiment, count in parts by weight, the first traditional Chinese medicinal components include:Lotus seeds 8~ 12 parts, 8~12 parts of smilax, 3~7 parts of the membrane of a chicken's gizzard, 8~12 parts of Chinese yam, 8~12 parts of Gorgon fruit, 8~12 parts of Semen Coicis, the root of kudzu vine 8~12 Part.Preferably, lotus seeds can be 9 parts, 11 parts, and smilax can be 9 parts, 11 parts, and the membrane of a chicken's gizzard can be 4 parts, 6 parts, and Chinese yam can Think 9 parts, 11 parts, Gorgon fruit can be 9 parts, 11 parts, and Semen Coicis can be 9 parts, 11 parts, and the root of kudzu vine can be 9 parts, 11 parts.
Further, in the present invention preferably embodiment, count in parts by weight, the second traditional Chinese medicinal components include:Russule 8~ 12 parts, 8~12 parts of Agricus blazei, 3~7 parts of the stem of noble dendrobium, 3~7 parts of mountain honeywort, 0.2~0.8 part of STEVIA REBAUDIANA, 3~7 parts of blue or green money willow.It is more excellent , russule can be 9 parts, 11 parts, Agricus blazei can be 9 parts, 11 parts, the stem of noble dendrobium can be 4 parts, 6 parts, mountain honeywort can be 4 parts, 6 parts, STEVIA REBAUDIANA can be 0.3 part, 0.4 part, 0.6 part, 0.7 part, and blue or green money willow can be 4 parts, 6 parts.
Lotus seeds, it is sweet, puckery, put down.Returns spleen, kidney, the heart channel of Hang-Shaoyin.With reinforcing spleen and kidney, the effect of mental-tranquilization.Lotus seeds contain abundant Protein, fat and carbohydrate, calcium, phosphorus and the potassium content in lotus seeds are very abundant, have and nourish qi-restoratives, improve body and exempt from The effect of epidemic disease power.
Smilax, it is sweet, light, put down.Return liver, stomach.With removing toxic substances, the effect of dehumidifying.
The membrane of a chicken's gizzard, it is sweet, put down.Returns spleen, stomach, small intestine, bladder warp.With stomach strengthening and digestion promoting, the effect for the treatment of stranguria fossil.The membrane of a chicken's gizzard can To strengthen the motion of the secretory volume of gastric juice and stomach, promote as Secretion.
Chinese yam, it is sweet, flat.Returns spleen, lung, kidney channel.With tonifying spleen nourishing the stomach, engender liquid and benefic lung, the effect of kidney tonifying.Sugar contained by Chinese yam Albumen is hydrolyzed to protein and carbohydrate in vivo, plays the role of to reduce blood glucose, contained amylase, which has, helps food digestion, water Solve the effect that starch is glucose.Chinese yam boosting qi and nourishing yin, strengthen immunity of organisms, adjust endocrine.
Gorgon fruit, it is sweet, puckery, put down.Returns spleen, kidney channel.The effect of with kidney-nourishing tonifying spleen.Its performance is similar to lotus seeds, tonifying middle-Jiao and Qi, Nourish strong, enhancing immunocompetence.
Semen Coicis, it is sweet it is light, be slightly cold, be nontoxic.Returns spleen, stomach, lung, big field warp.With clearing heat and promoting diuresis, the effect of strengthening the spleen and stomach.Semen Coicis There is hypoglycemic, anti-inflammatory and enhancing immunologic function.
The root of kudzu vine, it is sweet, pungent, it is cool.Returns spleen, stomach, lung channel.Bring down a fever, promote the production of body fluid to quench thirst with expelling pathogenic factors from muscles and skin, it is clearing and activating the channels and collaterals the effect of.The root of kudzu vine Extraction flavonoid substances can improve the symptom of diabetic.The extract of the root of kudzu vine can resolve into " sugar " that is deposited in blood For example, protrude into cell interior and be converted into energy, simultaneously bi-directionally adjust blood glucose, recover itself and change sugared instinct, quickly repair Multiple damaged cell, make pancreatic cell regeneration, nutrition pancreas, strengthen body immunity.
Lotus seeds, smilax, the membrane of a chicken's gizzard, Chinese yam, Gorgon fruit, Semen Coicis and root of kudzu vine compatible use, there is reinforcing spleen and kidney, nourish strong Effect, strengthen body immunity, adjust blood in and cell in blood-sugar content, promote body sugar is absorbed. Mitigate diabetes symptom, auxiliary treatment diabetes.
Russule, it is the general name of all russules, also makes high mountain red, is a kind of fungi, contains abundant polysaccharide, amino acid and fat Fat acid, there is enriching yin, kidney tonifying, promoting blood circulation and other effects.Contain polysaccharide cancer-resisting substance in russule, be advantageous to blood circulation, reduce blood Cholesterol, sugar in liquid, also have the function that to increase immunity of organisms.
Agricus blazei is a kind of mushroom with medical value, and Agricus blazei contains active polysaccharide body, has strengthening healthy qi, enhancing Body immunity and other effects, also there is hypoglycemic, improvement hepatic and renal function.
The stem of noble dendrobium, it is sweet, it is slightly cold.Return stomach, kidney channel.With reinforcing stomach reg fluid, the effect of nourishing Yin and clearing heat.The dendrobium polysaccharide composition contained The secretion of insulin can be promoted, had the function that hypoglycemic with hypoglycemic.Meanwhile the traditional Chinese medical science thinks, the hair of diabetes and diabetes Raw, mainly with kidney-yin deficiency, the early heat of lung stomach is basic pathogenesis, and using deficiency of both qi and yin as pathological characteristic, the stem of noble dendrobium has the dry profit of yin-nourishing, heat-clearing The effect of, from interior regulation body, strengthen insulin active, reduce blood sugar level.
Mountain honeywort, and alias longevity grass, nectar tea, Tian Liangcao, Sweet Broomwort Herb, root dissipate racemosus draft, are born in barren drying more Hillside, hills, in the jungle of wilderness, branches and leaves delicate fragrance is sweet, is distributed in Yunnan Province of China, Sichuan, Guangxi, in the remote, thickly forested mountains of Tibet. With treatment diabetes, the effect of blood glucose is controlled.
STEVIA REBAUDIANA, it is composite family, sweetleaf Chrysanthemum herbaceos perennial.With treatment diabetes, blood glucose is reduced, is improved immune Power, the effect to enhance metabolism.
Blue or green money willow, rich in Organic nutrients such as abundant saponin(e, flavones, polysaccharide, can active balance human body glycometabolism, So as to reach hypoglycemic effect.
Russule, Agricus blazei, the stem of noble dendrobium, mountain honeywort, STEVIA REBAUDIANA and blue or green money willow compatible use, there is enriching yin and nourishing kidney, regulation sugared generation The effect thanked, sugar unnecessary in blood is eliminated, promote body to absorb sugar, while strengthen the immunity energy of body Power.Russule, Agricus blazei, the stem of noble dendrobium, mountain honeywort, the second traditional Chinese medicinal components and lotus seeds, smilax of STEVIA REBAUDIANA and blue or green money willow composition, in chicken The first traditional Chinese medicinal components that gold, Chinese yam, Gorgon fruit, Semen Coicis and the root of kudzu vine form are used cooperatively, and have the function that Synergistic, strengthen body The ability of sugared content is adjusted, promotes absorption of the patient to sugar, mitigates diabetes symptom, reduce blood-sugar content, for treatment sugar Urine disease has preferable effect.
Further, in the present invention preferably embodiment, count in parts by weight, the first traditional Chinese medicinal components include lotus seeds 10 Part, 10 parts of smilax, 5 parts of the membrane of a chicken's gizzard, 10 parts of Chinese yam, 10 parts of Gorgon fruit, 10 parts of Semen Coicis, 10 parts of the root of kudzu vine, the second traditional Chinese medicinal components include Red 10 parts of mushroom, 10 parts of Agricus blazei, 5 parts of the stem of noble dendrobium, 5 parts of mountain honeywort, 0.5 part of sweetleaf grass, during 5 parts of blue or green money willow, drug effect is more.This hair The Chinese medicine of bright offer also includes the auxiliary material selected from least one of binding agent, disintegrant, lubricant., will by adding auxiliary material Different formulations is made in Chinese medicine.
Present invention also offers a kind of preparation method for being used to treat the Chinese medicine composition of diabetes, including:
The first traditional Chinese medicinal components are weighed in proportion, are crushed after clean dry, mix to obtain the first medicinal powder.In order to strengthen human body to medicine The absorption of thing, preferably, component is dried 4~6 hours under conditions of 40~60 DEG C, using superfine communication technique by raw material powder It is broken to more than 800 mesh.
The second traditional Chinese medicinal components are weighed in proportion, are crushed after clean dry, mix to obtain the second medicinal powder.In order to strengthen human body to medicine The absorption of thing, preferably, component is dried 4~6 hours under conditions of 40~60 DEG C, the grain of the second traditional Chinese medicinal components through crushing Footpath is 10~100 mesh.
This is used for the preparation method for treating the Chinese medicine composition of diabetes, and medicine is made by the way of medicinal material directly to be beaten to powder Agent so that all the components in medicinal material can be used as medicine, and medicinal material utilization rate is up to more than 99%, while the technique of this method is simple, The drug effect of obtained medicament is notable.
As another implementation, the method decocted can be used, extracts the active ingredient in traditional Chinese medicinal components.Specifically , use volume fraction to extract 1~3 in 60~80 DEG C of backflows to the first traditional Chinese medicinal components for 50%~60% ethanol water It is secondary, extract 6~8 hours every time.The first product is concentrated and dried to obtain after extracted many times liquid is mixed.Use volume fraction for 50%~ 60% ethanol water extracts 1~3 time to the second traditional Chinese medicinal components in 60~80 DEG C of backflows, extracts 6~8 hours every time.To be more The second product is concentrated and dried to obtain after secondary leaching liquor mixing.
Dried first product, the second product are mixed with auxiliary material respectively, different formulations is made as needed.The system Preparation Method is handled raw material, effective component extracting, further enhances absorption of the human body to medicine, quick.
It is provided by the present invention for the instructions of taking of Chinese medicine composition for treating diabetes:Every morning on an empty stomach, with 40 ~60 DEG C of warm water is taken after mixing it with water the first traditional Chinese medicinal components, is 20~30 grams each taking dosage, 30 days are a course for the treatment of.Meanwhile the daily noon Before meal and dinner, brew the second traditional Chinese medicinal components at least five minutes with boiling water, taken when being cooled to 40 DEG C, be 20 each taking dosage ~30 grams, 30 days are a course for the treatment of.In order to convenient to take, the second traditional Chinese medicinal components can be made as bag tea, conveniently brewed.
A kind of Chinese medicine composition for being used to treat diabetes that the present invention also provides has for preventing and treating diabetes and diabetes There is preferable effect, can be used for the medicine for preparing treatment diabetes.
The feature and performance of the present invention are described in further detail with reference to embodiments.
Embodiment 1
A kind of Chinese medicine composition for being used to treat diabetes is present embodiments provided, is made by following preparation method:
The first traditional Chinese medicinal components are weighed in proportion, including:8~12 parts of lotus seeds, 8~12 parts of smilax, 3~7 parts of the membrane of a chicken's gizzard, mountain 8~12 parts of medicine, 8~12 parts of Gorgon fruit, 8~12 parts of Semen Coicis, 8~12 parts of the root of kudzu vine.Crushed after clean dry, mix to obtain the first medicinal powder. Said components are dried 4~6 hours under conditions of 40~60 DEG C, raw material is crushed to by 800 mesh using superfine communication technique.
The second traditional Chinese medicinal components are weighed in proportion, including:8~12 parts of russule, 8~12 parts of Agricus blazei, 3~7 parts of the stem of noble dendrobium, mountain honey 3~7 parts of grass, 0.2~0.8 part of STEVIA REBAUDIANA, 3~7 parts of blue or green money willow.Crushed after clean dry, mix to obtain the second medicinal powder.By above-mentioned group Divide and dried 4~6 hours under conditions of 40~60 DEG C, the particle diameter of the second traditional Chinese medicinal components through crushing is 10~100 mesh.
The first traditional Chinese medicinal components and the second traditional Chinese medicinal components are packed respectively.
Embodiment 2
A kind of Chinese medicine composition for being used to treat diabetes is present embodiments provided, is made by following preparation method:
The first traditional Chinese medicinal components are weighed in proportion, including:8~12 parts of lotus seeds, 8~12 parts of smilax, 3~7 parts of the membrane of a chicken's gizzard, mountain 8~12 parts of medicine, 8~12 parts of Gorgon fruit, 8~12 parts of Semen Coicis, 8~12 parts of the root of kudzu vine.Crushed after clean dry, mix to obtain the first medicinal powder. Said components are dried 4~6 hours under conditions of 40~60 DEG C, raw material is crushed to by 800 mesh using superfine communication technique.
The second traditional Chinese medicinal components are weighed in proportion, including:8~12 parts of russule, 8~12 parts of Agricus blazei, 3~7 parts of the stem of noble dendrobium, mountain honey 3~7 parts of grass, 0.2~0.8 part of STEVIA REBAUDIANA, 3~7 parts of blue or green money willow.Crushed after clean dry, mix to obtain the second medicinal powder.By above-mentioned group Divide and dried 4~6 hours under conditions of 40~60 DEG C, the particle diameter of the second traditional Chinese medicinal components through crushing is 10~100 mesh.
The first traditional Chinese medicinal components and the second traditional Chinese medicinal components are packed respectively.
Embodiment 3
A kind of Chinese medicine composition for being used to treat diabetes is present embodiments provided, is made by following preparation method:
The first traditional Chinese medicinal components are weighed in proportion, including:8~12 parts of lotus seeds, 8~12 parts of smilax, 3~7 parts of the membrane of a chicken's gizzard, mountain 8~12 parts of medicine, 8~12 parts of Gorgon fruit, 8~12 parts of Semen Coicis, 8~12 parts of the root of kudzu vine.Crushed after clean dry, mix to obtain the first medicinal powder. Said components are dried 4~6 hours under conditions of 40~60 DEG C, raw material is crushed to by 800 mesh using superfine communication technique.
The second traditional Chinese medicinal components are weighed in proportion, including:8~12 parts of russule, 8~12 parts of Agricus blazei, 3~7 parts of the stem of noble dendrobium, mountain honey 3~7 parts of grass, 0.2~0.8 part of STEVIA REBAUDIANA, 3~7 parts of blue or green money willow.Crushed after clean dry, mix to obtain the second medicinal powder.By above-mentioned group Divide and dried 4~6 hours under conditions of 40~60 DEG C, the particle diameter of the second traditional Chinese medicinal components through crushing is 10~100 mesh.
The first traditional Chinese medicinal components and the second traditional Chinese medicinal components are packed respectively.
Embodiment 4
A kind of Chinese medicine composition for being used to treat diabetes is present embodiments provided, is made by following preparation method:
The first traditional Chinese medicinal components are weighed in proportion, including:8~12 parts of lotus seeds, 8~12 parts of smilax, 3~7 parts of the membrane of a chicken's gizzard, mountain 8~12 parts of medicine, 8~12 parts of Gorgon fruit, 8~12 parts of Semen Coicis, 8~12 parts of the root of kudzu vine.Crushed after clean dry, mix to obtain the first medicinal powder. Said components are dried 4~6 hours under conditions of 40~60 DEG C, raw material is crushed to by 800 mesh using superfine communication technique.
The second traditional Chinese medicinal components are weighed in proportion, including:8~12 parts of russule, 8~12 parts of Agricus blazei, 3~7 parts of the stem of noble dendrobium, mountain honey 3~7 parts of grass, 0.2~0.8 part of STEVIA REBAUDIANA, 3~7 parts of blue or green money willow.Crushed after clean dry, mix to obtain the second medicinal powder.By above-mentioned group Divide and dried 4~6 hours under conditions of 40~60 DEG C, the particle diameter of the second traditional Chinese medicinal components through crushing is 10~100 mesh.
The first traditional Chinese medicinal components and the second traditional Chinese medicinal components are packed respectively.
Embodiment 5
A kind of Chinese medicine composition for being used to treat diabetes is present embodiments provided, is made by following preparation method:
The first traditional Chinese medicinal components are weighed in proportion, including:10 parts of lotus seeds, 10 parts of smilax, 5 parts of the membrane of a chicken's gizzard, 10 parts of Chinese yam, Gorgon euryale It is real 10 parts, 10 parts of Semen Coicis, 10 parts of the root of kudzu vine.Crushed after clean dry, mix to obtain the first medicinal powder.By condition of the said components at 60 DEG C Lower drying 5 hours, raw material is crushed to by 900 mesh using superfine communication technique.
The second traditional Chinese medicinal components are weighed in proportion, including:Red 10 parts of mushroom, 10 parts of Agricus blazei, 5 parts of the stem of noble dendrobium, 5 parts of mountain honeywort, 0.5 part of sweetleaf grass, 5 parts of blue or green money willow.Crushed after clean dry, mix to obtain the second medicinal powder.By said components under conditions of 60 DEG C Dry 4 hours, the particle diameter of the second traditional Chinese medicinal components through crushing is 100 mesh.
The first traditional Chinese medicinal components and the second traditional Chinese medicinal components are packed respectively.
Comparative example 1
This comparative example provides a kind of Chinese medicine composition for being used to treat diabetes, is made by following preparation method:
The first traditional Chinese medicinal components are weighed in proportion, including:8~12 parts of lotus seeds, 8~12 parts of smilax, 3~7 parts of the membrane of a chicken's gizzard, mountain 8~12 parts of medicine, 8~12 parts of Gorgon fruit, 8~12 parts of Semen Coicis, 8~12 parts of the root of kudzu vine.Crushed after clean dry, mix to obtain the first medicinal powder. Said components are dried 4~6 hours under conditions of 40~60 DEG C, raw material is crushed to by 800 mesh using superfine communication technique.
Comparative example 2
This comparative example provides a kind of Chinese medicine composition for being used to treat diabetes, is made by following preparation method:
Weigh the second traditional Chinese medicinal components respectively in proportion, including:8~12 parts of russule, 8~12 parts of Agricus blazei, 3~7 parts of the stem of noble dendrobium, 3~7 parts of mountain honeywort, 0.2~0.8 part of STEVIA REBAUDIANA, 3~7 parts of blue or green money willow.Crushed after clean dry, mix to obtain the second medicinal powder.Will be upper State component to dry 4~6 hours under conditions of 40~60 DEG C, the particle diameter of the second traditional Chinese medicinal components through crushing is 10~100 mesh.
The animal experiment of test example 1
1. Animal Model
Rat 80 is taken, body weight (20 ± 2) g, cuts off pancreas.
2. packet and medicine feed
Choose the rat 80 being successfully established only to weigh, mark the price, be randomly divided into 8 groups, every group 10, correspond to experimental group 1 respectively ~7, control group.Control group is since after modeling through feeding 0.85wt% sodium chloride second day.Example 1~5, contrast respectively The medicine 10g that example 1, comparative example 2 provide, wherein the first traditional Chinese medicinal components in embodiment 1~5 are 4g, and the second traditional Chinese medicinal components are 6g, The drug solution that concentration is all 2g/ml is made, rat is fed by 1ml/100g.
3. collection of specimens
Observe the blood glucose value of the activity detection rat of rat.
4. result and analysis
When feeding 2~3 weeks, the rat of control group hardly moves, and dead after a period of time.Feed embodiment 1~5 The rat normal activity of the compound medicine of offer, the blood glucose value of detection are essentially normal value, wherein feeding comparative example 1 and comparative example The rat blood sugar value of the compound medicines of 2 offers is compared before feeding and reduced, but without recovery normal value.Illustrate prepared by embodiment 1~5 Compound medicine to reduce blood glucose there is effect.Wherein, the drug effect of embodiment 5 is optimal.
The clinical test of test example 2
1. case is selected in
All cases go out the patient of diabetes and diabetes from certain hospital diagnosis.Selected 60 patients are as research pair As 20~45 years old age.It is classified as 4 groups, every group of 15 people, what group 1~3 was provided using embodiment 5, stadium of each group patient etc. General information compares, no significant difference (p>0.05).
2. treatment method
Patient takes the compound medicine of the offer of embodiment 5 by the way of oral.Patient's empty stomach every morning of group 1, is used 40~60 DEG C of warm water is taken after mixing it with water the first traditional Chinese medicinal components, is 20 grams each taking dosage, 30 days are a course for the treatment of.Meanwhile daily lunch And before dinner, brew the second traditional Chinese medicinal components at least five minutes with boiling water, taken when being cooled to 40 DEG C, it is 20 each taking dosage Gram, 30 days are a course for the treatment of.The instructions of taking of group 2 is identical with group 1, unlike each taking dosage be 10 grams, organize 3 and take Method is identical with group 1, the difference is that being 30 grams each taking dosage.The patient of group 4 takes existing Chinese medicine preparation.Every group takes With 3 courses for the treatment of.
3. curative effect determinate standard
Cure:Basic related symptoms and blood glucose value are back to normal, and health, no recurrence was observed during the follow-up period of 6 months.
Effectively:Sense of discomfort is obviously reduced, and blood glucose value reduces, and no recurrence was observed during the follow-up period of 6 months, and main inspection prompting has substantially Recover.
It is invalid:Edema has no abatement, and blood glucose inspection does not improve.
Each group the results are shown in Table 1.
4. result and analysis
The clinical efficacy result table of table 1
Group Cure Effectively It is invalid Total effective rate
1 4 8 3 80%
2 6 7 2 86.7%
3 5 7 3 80%
4 5 8 2 86.7%
Obtained according to table 1:The total effective rate of the patient of the compound medicine provided each taking 20g embodiments 5 is higher, illustrates this Dosage is relatively reasonable.The total effective rate of group 1~groups 3 is higher, illustrate the preparation method more science of the offer of embodiment 5, therefore Therapeutic effect is good.
Test example model case
Huang, man, 38 years old, before taking Chinese medicine composition provided by the invention, fasting blood-glucose 16mmol/L, postprandial blood sugar For 26mmol/L, Chinese medicine composition provided by the invention is taken 30 days, fasting blood-glucose is down to 11mmol/L, and postprandial blood sugar is down to 20mmol/L, dizzy symptom mitigation, enuresis nocturna are reduced.
Feng, man, before taking Chinese medicine composition provided by the invention, fasting blood-glucose 9mmol/L, postprandial blood sugar is 12mmol/L, takes Chinese medicine composition provided by the invention 30 days, and fasting blood-glucose is down to 7mmol/L, and postprandial blood sugar is down to 10mmol/L, symptom mitigation of quenching one's thirst, enuresis nocturna are reduced.
Zeng, female, before taking Chinese medicine composition provided by the invention, fasting blood-glucose 10mmol/L, postprandial blood sugar is 13mmol/L, takes Chinese medicine composition provided by the invention 30 days, and fasting blood-glucose is down to 6.5mmol/L, and postprandial blood sugar is down to 9mmol/L, enuresis nocturna are reduced, and pin edematous condition disappears.
In summary, the present invention is studied with reference to modern medicines, and the balanced nutrients prescription of science is formed with reference to clinical experience, should Prescription has the effect of " reinforcing spleen and kidney, nourishing strong ", can adjust immunity of organisms, strengthens body immunity, adjusts blood Blood-sugar content in liquid and in cell, sugar unnecessary in blood is eliminated, promote patient to absorb sugar, it is auxiliary by nutrition Intervention is helped, mitigates diabetes symptom, reduces blood-sugar content, there is preferable effect for treatment diabetes.
Embodiments described above is part of the embodiment of the present invention, rather than whole embodiments.The reality of the present invention The detailed description for applying example is not intended to limit the scope of claimed invention, but is merely representative of the selected implementation of the present invention Example.Based on the embodiment in the present invention, what those of ordinary skill in the art were obtained under the premise of creative work is not made Every other embodiment, belongs to the scope of protection of the invention.

Claims (10)

1. a kind of Chinese medicine composition for being used to treat diabetes, it is characterised in that including the first traditional Chinese medicinal components and the second Chinese medicine group Point, count in parts by weight,
First traditional Chinese medicinal components include:5~15 parts of lotus seeds, 5~15 parts of smilax, 1~9 part of the membrane of a chicken's gizzard, 5~15 parts of Chinese yam, 5~15 parts of Gorgon fruit, 5~15 parts of Semen Coicis, 5~15 parts of the root of kudzu vine;
Second traditional Chinese medicinal components include:5~15 parts of russule, 5~15 parts of Agricus blazei, 1~9 part of the stem of noble dendrobium, 1~9 part of mountain honeywort, sweet tea 0.1~1 part of leaf chrysanthemum, 1~9 part of blue or green money willow.
2. the Chinese medicine composition according to claim 1 for being used to treat diabetes, it is characterised in that count in parts by weight, First traditional Chinese medicinal components include:8~12 parts of the lotus seeds, 8~12 parts of the smilax, 3~7 parts of the membrane of a chicken's gizzard are described 8~12 parts of Chinese yam, 8~12 parts of the Gorgon fruit, 8~12 parts of the Semen Coicis, 8~12 parts of the root of kudzu vine.
3. the Chinese medicine composition according to claim 1 for being used to treat diabetes, it is characterised in that count in parts by weight, Second traditional Chinese medicinal components include:8~12 parts of the russule, 8~12 parts of the Agricus blazei, 3~7 parts of the stem of noble dendrobium, the mountain 3~7 parts of honeywort, 0.2~0.8 part of the STEVIA REBAUDIANA, 3~7 parts of the blue or green money willow.
4. the Chinese medicine composition according to claim 2 for being used to treat diabetes, it is characterised in that count in parts by weight, First traditional Chinese medicinal components include:10 parts of the lotus seeds, 10 parts of the smilax, 5 parts of the membrane of a chicken's gizzard, 10 parts of the Chinese yam, 10 parts of the Gorgon fruit, 10 parts of the Semen Coicis, 10 parts of the root of kudzu vine.
5. the Chinese medicine composition according to claim 3 for being used to treat diabetes, it is characterised in that count in parts by weight, Second traditional Chinese medicinal components include:10 parts of the russule, 10 parts of the Agricus blazei, 5 parts of the stem of noble dendrobium, 5 parts of the mountain honeywort, institute State 0.5 part of STEVIA REBAUDIANA, 5 parts of the blue or green money willow.
6. a kind of preparation method for being used to treat the Chinese medicine composition of diabetes as described in any one of Claims 1 to 5, it is special Sign is, including:Respectively by first traditional Chinese medicinal components and second traditional Chinese medicinal components drying, crushing.
7. the preparation method according to claim 6 for being used to treat the Chinese medicine composition of diabetes, it is characterised in that through powder The particle diameter of broken first traditional Chinese medicinal components is more than 800 mesh.
8. the preparation method according to claim 6 for being used to treat the Chinese medicine composition of diabetes, it is characterised in that through powder The particle diameter of broken second traditional Chinese medicinal components is 10~100 mesh.
9. a kind of preparation method for being used to treat the Chinese medicine composition of diabetes as described in any one of Claims 1 to 5, it is special Sign is, including:First traditional Chinese medicinal components and the second Chinese medicine group are decocted respectively.
10. the Chinese medicine composition for being used to treat diabetes as described in any one of Claims 1 to 5 is preparing treatment Rezulin Application in thing.
CN201711210319.7A 2017-11-27 2017-11-27 Chinese medicine composition for treating diabetes and its preparation method and application Pending CN107737280A (en)

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