CN106418537A - Composition, as well as preparation method, preparation and application thereof - Google Patents

Composition, as well as preparation method, preparation and application thereof Download PDF

Info

Publication number
CN106418537A
CN106418537A CN201610867779.6A CN201610867779A CN106418537A CN 106418537 A CN106418537 A CN 106418537A CN 201610867779 A CN201610867779 A CN 201610867779A CN 106418537 A CN106418537 A CN 106418537A
Authority
CN
China
Prior art keywords
extractor
maintained
extract
preparation
parts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610867779.6A
Other languages
Chinese (zh)
Inventor
曹志坚
冯明永
刘建
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CHUXIONG BAICAOLING PHARMACEUTICAL DEVELOPMENT CO LTD
Original Assignee
CHUXIONG BAICAOLING PHARMACEUTICAL DEVELOPMENT CO LTD
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CHUXIONG BAICAOLING PHARMACEUTICAL DEVELOPMENT CO LTD filed Critical CHUXIONG BAICAOLING PHARMACEUTICAL DEVELOPMENT CO LTD
Priority to CN201610867779.6A priority Critical patent/CN106418537A/en
Publication of CN106418537A publication Critical patent/CN106418537A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Abstract

The invention discloses a composition, as well as a preparation method, a preparation and application thereof. The composition comprises the following raw materials in parts by weight: 50 to 60 parts of kudzuvine root extract, 5 to 10 parts of kudzuvine flower ultrafine powder, 11 to 22 parts of rhizoma phragmitis extract, 2.5 to 5 parts of honey and 1.5 to 3 parts of emblic leafflower fruit fine powder. The composition disclosed by the invention has the effects of promoting the production of body fluid to relieve thirst, relieving exterior syndrome to reduce heat, promoting spleen yang to stop diarrhea, detoxifying, enlivening the spleen, protecting a body from being damaged by drinking, and the like. The raw materials of the compositions are pre-treated by adopting different methods; kudzuvine flower serving as a raw material has high active ingredients for detoxifying and enlivening the splee and is high in heat sensitivity, and the bioavailability is beneficial to improving by adopting the method provided by the invention; rhizoma phragmitis and kudzuvine roots are low in active ingredients; through the extracting method of the invention, the effects of clearing heat, relieving pain, and promoting the production of the body fluid to relieve the thirst are enhanced; according to the principle of optimizing a formula and enhancing the concentration of components for clearing the heat and relieving the pain, the used process is beneficial to the appearance, removing medicinal flavor, and enhancing the effects of clearing heat, relieving pain, and promoting the production of the body fluid to relieve the thirst.

Description

A kind of composition and preparation method thereof, preparation and application
Technical field
The invention belongs to field of health care products is and in particular to a kind of composition and preparation method thereof, preparation and application.
Background technology
China is the big country of liquor consumption since ancient times, just has ten hundreds of liquor production producers and white wine product at present Board manufactures all kinds of white wine continuous, but is as consumer to the pay attention to day by day of health idea with to life quality-mind Raising it is desirable to enjoy drink enjoyment while be not also harmful to the health, crave for and Related product can be had to can solve the problem that problem.Due to the root of kudzu vine originally The characteristic that body has, Pueraria DC product in the market is various, but also far can not meet people to the quality of such product, Mouthfeel, effect consumption demand;Many deficiencies are also had on preparation method, therefore, develops a kind of health care significant product right and wrong Often necessary.
Content of the invention
The first object of the present invention is to provide a kind of composition, and the second purpose is to provide a kind of preparation side of composition Method, the 3rd purpose is to provide a kind of preparation of composition, and the 4th purpose is to provide a kind of application of composition.
The first object of the present invention is achieved in that the raw material including following weight portion:50 ~ 60 parts of kudzu root extract, 5 ~ 10 parts of flower of Radix Puerariae Ultramicro-powder, 11 ~ 22 parts of Rhizoma Phragmitis extract, 2.5 ~ 5 parts of honey, 1.5 ~ 3 parts of emblic fine powder.
The second object of the present invention be achieved in that including following steps:
1)Weigh:Weigh 50 ~ 60 parts of kudzu root extract, 5 ~ 10 parts of flower of Radix Puerariae Ultramicro-powder, 11 ~ 22 parts of Rhizoma Phragmitis extract, honey 2.5 ~ 5 parts, 1.5 ~ 3 parts of emblic fine powder, standby;
2)Mixing:By step 1)The material equal proportion of middle weighing adds in double oar mixers of operating, positive and negative operating mixed processing 4 Secondary, mix 10 ~ 15 minutes every time, mix discharging, obtain composition.
The third object of the present invention is achieved in that described preparation is to add pharmaceutically to connect in described composition The auxiliary material being subject to is prepared into capsule, tablet, powder, granule, liquid preparation, pill.
The fourth object of the present invention is achieved in that described composition in preparation prevention/auxiliary treatment solution drinks, height Application in blood pressure, high fat of blood similar drug or health food.
Beneficial effects of the present invention:
1st, the composition of the present invention has and promotes the production of body fluid to quench thirst, induces sweat and bring down a fever, the effects such as Shengyang Zhixie, removing toxic substances are amusing, solve and drink The problem being harmful to the health.
2nd, the raw material of the present invention adopts different preprocess methods, and the removing toxic substances of flower of Radix Puerariae raw material is amusing, and effective ingredient is high, temperature-sensitive Property strong, the processing method of the present invention is conducive to improving bioavilability;Reed rhizome, root of kudzu vine raw material effective ingredient are low, so using this The extracting method of invention, to extract effective ingredient, strengthens clearing away heat to and alleviating pain, promote the production of body fluid to quench thirst effect, this process advan is in U.S. of product See, go flavour of a drug, flavouring taste, strengthen clearing away heat to and alleviating pain, promote the production of body fluid to quench thirst, effect of being amusing of detoxifying, so that product active ingredient concentration is significantly carried High, mouthfeel is more preferable, effect is more notable.
3rd, efficacy effect in this composition for the kudzu root extract in raw material of the present invention:There is heat-clearing, fall fire, toxin expelling, rush Enter the effect such as liver cell regeneration, delaying senility, anti-arrhythmia cordis, looks beauty treatment;Efficacy effect in this composition for the flower of Radix Puerariae: There is removing toxic substances be amusing, restoring consciouness pain relieving, promote the excretion of alcohol fast decoupled, relieving thirst and restlessness, anti-nausea, reducing blood lipid etc. to act on;Reed rhizome carries Take the effect of thing effect in this composition:There is the effect such as clearing heat and promoting fluid, relieving restlessness, preventing or arresting vomiting, diuresis;Honey is in this composition Efficacy effect:There is replenishing qi and blood, nourishing blood and tranquilization, strengthen immunity, the effect such as improve looks, relax bowel;Emblic fine powder here The effect of effect in composition:There is the effect such as anti-oxidant, liver protection, anti-inflammatory, clearing heat and cooling blood, food digesting stomach fortifying, cough-relieving of promoting the production of body fluid;So that Gegen tablets of the present invention are in good taste, restoring consciouness pain relieving, promote the production of body fluid, relieving restlessness, preventing or arresting vomiting and can strengthen immunity, solve synthesis of drinking A difficult problem for disease.
4th, inventive formulation combinatorial principle:The raw material root of kudzu vine, flower of Radix Puerariae, are that in the present invention, Antialcoholic liver-protecting plays a decisive role Principal ingredients, but cold in nature, and easily consumption hinders vigour, body fluid, the impairment of the spleen;Raw material reed rhizome reducing fever and causing diuresis, can promote the quick of wine poison Excretion, but cold in nature also easily consumption hinders vigour, body fluid, the impairment of the spleen, and so increase joining honey and emblic fine powder, honey is mild-natured, tool There are coordinating the drug actions of a prescription, bonding, fructose therein, glucose can quickly additional heat, vigour;Enzyme therein can be with invigorating the spleen Stomach, help digestion, promote absorb, honey not only counteracts the side effect of the raw materials such as reed rhizome, the root of kudzu vine, flower of Radix Puerariae, but also can promote The booster action of Antialcoholic liver-protecting is played in the decomposition absorption of alcohol, alleviation is nervous, promote enterocinesia to strengthen effect of ejecting poison, promotion This product absorbs and is beneficial to fast onset;The tartaric acid of emblic fine powder can with food digesting stomach fortifying and promote the production of body fluid, fructose can with additional heat and Vigour, natural complex C and hepatocuprein can with strengthen immunity, emblic fine powder not only counteract reed rhizome, the root of kudzu vine, The side effect of the raw materials such as flower of Radix Puerariae, but also there is anti-aging, anticancer, the effect of suppression hepatitis B.For projecting effect, adopt The supplementary vigour of various raw material effects and strengthening excretion, main effect and auxiliary effect, promotion absorb and strengthen metabolism etc. and be collocated with each other; Extract dispensing and the direct dispensing of raw material combine, and constitute the formula of present invention optimization.
5th, the preparation method of the Gegen tablets of the present invention adopts Modern preparations technology, formula upper using promoting the production of body fluid to quench thirst, heat-clearing sharp Urine, removing toxic substances are amusing, promote alcohol decompose, help digestion, the raw material prescription of clearing away heat to and alleviating pain is arranged in pairs or groups, product make tablet make processing, take, Preserve, carry extremely convenient, create condition for realizing large-scale production.
6th, the present invention utilizes raw material flower of Radix Puerariae Ultramicro-powder mixing kudzu root extract, Rhizoma Phragmitis extract, honey, emblic fine powder Preparation technology, shorten process time make in raw material flower of Radix Puerariae Ultramicro-powder, kudzu root extract, Rhizoma Phragmitis extract, honey, emblic Impact effect and mouthfeel active ingredient be difficult lose, ensure that simultaneously kudzu root extract, the efficacy effect of Rhizoma Phragmitis extract and Maintain the pure natural fragrance of honey and melt and dissolved in product, make products taste, olfactory more preferable.Wherein kudzu root extract preparation side The advantage of method:Root of kudzu vine raw material contains a large amount of fibers and starch, and active ingredient ratio is relatively low, not only effective ingredient and the absorption of direct dispensing Rate is low can not to manifest effect, and preparation processing is difficult, so needing extracts active ingredients out dispensing again.For guaranty Matter, cost doulbe-sides' victory, technique adopt 75% edible alcohol extract it can be ensured that active ingredient farthest selective dissolution, it is to avoid The impurity dissolutions such as much starch;The present invention is extracted simultaneously and is concentrated, and is seen off concentration, alcohol quilt after solute dissolution at once It is condensed into fresh solvent after evaporation and fills into extractor at any time, the amount of liquid seen off and the quantity of solvent supplemented are equal, keep liquid in tank Position balance, in extraction process, in inspissator, solute is on the increase, and in extractor, solute constantly reduces, and makes solute in extractor molten Go out gradient to increase, extract more completely, speed faster.In the case that equivalent feeds intake, water extraction much starch dissolution, individually gradation relatively Concentrate again after extraction and need to take 10 hours, total solvent amount needs 10 times, coal consumption needs 2000 kilograms, power consumption need to 600 degree, extraction yield The method having 10%, time-consuming only 5 hours of this method, only 6 times of total solvent amount, only 1100 kilograms of coal consumption, only 330 degree of power consumption, extraction Yield reaches 12%.Flower of Radix Puerariae Ultramicro-powder prepares advantage:In flower of Radix Puerariae raw material, the composition of activating spleen by relieving alcoholism is higher, the process side of the present invention Method promotes to absorb raising bioavilability, prominent product efficacy.The advantage of Rhizoma Phragmitis extract preparation method:Reed rhizome raw material contains a large amount of Fiber, active ingredient ratio is relatively low, direct dispensing not only effective ingredient and absorptivity is low can not manifest effect, and preparation processing Difficulty, so need extracts active ingredients out dispensing again.For guaranteed quality, cost doulbe-sides' victory, technique is extracted with drinking water, It is able to ensure that the requirement of active ingredient at utmost dissolution, the present invention is extracted simultaneously and concentrates, horse back quilt after solute dissolution See concentration off, water is condensed into fresh solvent and fills into extractor at any time after being evaporated, the quantity of solvent phase of the amount of liquid seen off and supplement Deng, liquid level equilibrium in holding tank, in extraction process, in inspissator, solute is on the increase, and in extractor, solute constantly reduces, and makes to carry Take in tank solute dissolution gradient to increase, extract more completely, speed faster.In the case that equivalent feeds intake, relatively individually extract by several times Concentrate again afterwards and need to take 12 hours, total solvent amount need 14 times, coal consumption need 2500 kilograms, power consumption need 700 degree, extraction yield only have 12% method, this method takes only 7 hours, only 6 times of total solvent amount, only 1500 kilograms of coal consumption, only 400 degree of power consumption, extracts Rate reaches 15%.The advantage of emblic fine powder preparation method:The unfavorable preservation of wild fresh fruit of fructus phyllanthi, and contain a large amount of fibers, it is dried Difficulty, the aspect such as processing cost, preparation processing Feasible degree is all unfavorable, and the extracting method of the present invention is conducive to preserving, favorably In preparation processing, be conducive to improving bioavilability, technique takes short, good product quality, product granularity and reaches Ultramicro-powder rank, Be conducive to preparation processing and product efficacy.
Specific embodiment
With reference to embodiment, the present invention is further illustrated, but never in any form the present invention is any limitation as, Based on present invention teach that any conversion of being made or replacement, belong to protection scope of the present invention.
Composition of the present invention, including the raw material of following weight portion:50 ~ 60 parts of kudzu root extract, flower of Radix Puerariae ultra micro 5 ~ 10 parts of powder, 11 ~ 22 parts of Rhizoma Phragmitis extract, 2.5 ~ 5 parts of honey, 1.5 ~ 3 parts of emblic fine powder.
The extracting method of described kudzu root extract includes:
1)Root of kudzu vine dry plate is weighed and puts in extractor, the concentration of addition 6 ~ 8 times amount is 70% ~ 75% edible alcohol, soaks 6 ~ 8 hours;
2)Open the condenser of extractor and steam heating, in tank to be extracted temperature reach 75 DEG C, seethe with excitement in tank, alcohol steam When condensate liquid is back in tank, the temperature in extractor is maintained at 73 ~ 78 DEG C boils and carry 30 minutes;
3)Open the transfusion valve between extractor and outer circulation inspissator, so that the extract in extractor is entered by valve outer Circulation inspissator, is then turned on the steam heating of outer circulation inspissator, makes the vaporized alcohol in extract and return to extractor, lead to Cross extractor condenser and be condensed into liquid and be back to extractor, in extractor, the root of kudzu vine effective ingredient of dissolution is constantly extracted simultaneously Liquid band is to outer circulation inspissator;In extraction process, adjust transfusion valve opening be 1/3rd at, extractor steam heating pressure Power is maintained at 0.2 ~ 0.25MPa, inspissator steam heated pressure is maintained at 0.08 ~ 0.1MPa, condenser cooling water pressure is maintained at 0.3 ~ 0.4MPa, sealing and circulating 3 hours in this case;
4)Open the condenser of outer circulation inspissator, close steam heating and the condenser of extractor, by the extraction in extractor Liquid constantly puts into outer circulation inspissator, starts simultaneously at recovered alcohol, and the temperature in outer circulation inspissator is maintained at 73 ~ 78 DEG C; After the extract in extractor all discharges, the vaporized alcohol remaining in pueraria root residue is gone out and reclaims, when in extract and When alcohol concentration in slag is less than 40%, stop recovered alcohol;
5)Pueraria root residue is discharged, extract is concentrated in vacuo, keep vacuum in 60 ~ 65 DEG C of -0.07 ~ -0.075MPa, temperature, Being concentrated into proportion is 1.2 ~ 1.25, receives cream, condensed cream is uniformly laid on baking tray, baking tray is placed on the grill of rotation, protects Hold vacuum -0.07 ~ -0.075MPa, carry out microwave drying under the conditions of 60 ~ 65 DEG C of temperature, be dried and receive to during moisture 5% ~ 5.5% Material;Then the condensed cream being dried is pulverized with pulverizer, sieve, obtain the kudzu root extract that granularity is 80 ~ 120 mesh.
The preparation method of described flower of Radix Puerariae Ultramicro-powder be by flower of Radix Puerariae pulverizer pulverize, sieve, obtain granularity be 80 ~ The flower of Radix Puerariae fine powder of 120 mesh, then flower of Radix Puerariae fine powder is intermittently added in micronizer, keep rotating speed 200 ~ 300 turns/ Mir, stone roller rail pressure power are in 2 ~ 2.5kgf/cm2, air quantity is in 900 ~ 1300m3/ h, carries out ultramicro grinding, and obtaining granularity is 200 ~ 250 mesh Flower of Radix Puerariae Ultramicro-powder.
The extracting method of described Rhizoma Phragmitis extract includes:
1)Reed rhizome section is weighed and puts in extractor, add the drinking water of 6 ~ 8 times amount, soak 2 ~ 3 hours;
2)Open extractor condenser and steam heating, in tank to be extracted temperature reach 93 DEG C, seethe with excitement in tank, water vapour condensation When liquid is back in tank, keeps the temperature at 93 ~ 96 DEG C and boil and carry 30 minutes;
3)Open the transfusion valve between extractor and outer circulation inspissator, so that the extract in extractor is entered by valve outer Circulation inspissator, is then turned on the steam heating of outer circulation inspissator, then makes water evaporation therein become to steam using steam heating Vapour simultaneously returns to extractor, is condensed into liquid by extractor condenser and is back in extractor, simultaneously in extractor dissolution reed Root effective ingredient is constantly extracted liquid band to outer circulation inspissator;In extraction process, adjust transfusion valve opening be three/ At one, extractor steam heated pressure is maintained at 0.2 ~ 0.25MPa, inspissator steam heated pressure is maintained at 0.08 ~ 0.1MPa, Condenser cooling water pressure is maintained at 0.3 ~ 0.4MPa, in this case sealing and circulating 3 hours;
4)Open outer circulation and concentrate condenser, close steam heating and the condenser of extractor, by the extract in extractor not Break and put into outer circulation inspissator, until the extract in extractor all discharges;
5)By reed rhizome slag discharge, extract start concentrated in vacuo, keep vacuum in -0.07 ~ -0.075MPa, temperature 60 ~ 65 DEG C, being concentrated into proportion is 1.2 ~ 1.25, receives cream, condensed cream is uniformly laid on baking tray, baking tray is placed on the grill of rotation, Carry out microwave drying, when being dried to moisture 5% ~ 5.5% under the conditions of keeping vacuum -0.07 ~ -0.075MPa, 60 ~ 65 DEG C of temperature Rewinding;Then the reed rhizome cream being dried, is pulverized with pulverizer, sieves, and obtains the Rhizoma Phragmitis extract that granularity is 80 ~ 120 mesh.
The preparation method of described emblic fine powder includes:
1)It is maintained at 15 ~ 20 revs/min by after wild fresh fruit of fructus phyllanthi rejecting decayed fruit, impurity using drum-type fruit washing machine, cylinder rotating speed Clock, Water spray flow 5 ~ 10m3/ h, charging rate is maintained at 8 ~ 10 kg/minute, obtains the fresh fruit cleaning up, described water For drinking water;
2)Using fruit crusher, charging rate is maintained at 5 ~ 8 kg/minute, by the fresh fruit cleaning up be broken for granularity 2 ~ The particle of 5mm;
3)Using fruit pressafiner, rotating speed is maintained at 60 ~ 70 revs/min, and particle is at the uniform velocity added, and charging rate is maintained at 3 ~ 5 kg/minute, pomace is discharged, and underflow fruit juice flows out from bottom through filter screen;
4)Using centrifuge, drum speed is maintained at 1000 ~ 1500 revs/min, by step 3)The underflow fruit juice obtaining at the uniform velocity adds Enter, charging rate is maintained at 0.2 ~ 0.5 m3/ minute, the slag discharge isolated, obtain fruit juice clear liquid;
5)By step 4)The fruit juice clear liquid of gained is spray-dried, high speed centrifugal atomization device rotating speed be maintained at 6000 ~ 6500 turns/ Minute, adjust the air flow rate proportioning of air-supply and air inducing, so that spraying system is maintained between negative pressure 50 ~ 200Pa, tower top inlet temperature is protected Hold at 230 ~ 240 DEG C, bottom of towe outlet temperature is maintained at 110 ~ 120 DEG C, 10 beats/min of pulse rapping, stablize screw pump feed stream Amount, in 80 ~ 100L/ minute, is carried out continuously spray drying, obtains the emblic fine powder that granularity is 200 ~ 300 mesh.
The preparation method of composition of the present invention, including following steps:
1)Weigh:Weigh 50 ~ 60 parts of kudzu root extract, 5 ~ 10 parts of flower of Radix Puerariae Ultramicro-powder, 11 ~ 22 parts of Rhizoma Phragmitis extract, honey 2.5 ~ 5 parts, 1.5 ~ 3 parts of emblic fine powder, standby;
2)Mixing:By step 1)The material equal proportion of middle weighing adds in double oar mixers of operating in three times, and positive and negative operating is mixed Close and process 4 times, mix 10 ~ 15 minutes every time, mix discharging, obtain composition.
The preparation of composition of the present invention, described preparation is to add pharmaceutically to accept in described composition Auxiliary material is prepared into capsule, tablet, powder, granule, liquid preparation, pill.
The preparation method of described tablet comprises the following steps:
1)Pelletize:Described composition is added in the oscillating granulator of operating, makes wet granular, standby;
2)It is dried:Wet granular sanitation-grade stainless steel baking tray is installed, often 2 kilograms of disk, are uniformly paved with card, put into vacuum drying In case, airtight chamber door, open vacuum to -0.065 ~ -0.075MPa, slowly open steam, temperature control, at 60 ~ 65 DEG C, is dried 2 ~ 2.5 hours, discharging when drying to moisture is less than 7%, standby;
3)Whole grain:Dried material particles are added in pelletizing machine, filters out the particle of even particle size, standby;
4)Compressing tablet:Whole grain good particle rotary pelleting machine compressing tablet, makes standard circular piece, piece weight 0.5g, treats interior bag;
5)Sterilization, interior bag:After the tablet pressing is carried out disinfection, carry out bubble-cap or bottling.
A kind of application of composition, described application is described composition in preparation prevention/auxiliary treatment solution drinks, height Application in blood pressure, high fat of blood similar drug or health food.
Embodiment 1
The preparation of kudzu root extract:
1)Root of kudzu vine dry plate is weighed and puts in extractor, the concentration of addition 6 times amount is 75% edible alcohol, soaks 8 hours;
2)Open the condenser of extractor and steam heating, in tank to be extracted temperature reach 75 DEG C, seethe with excitement in tank, alcohol steam When condensate liquid is back in tank, the temperature in extractor is maintained at 73 ~ 78 DEG C boils and carry 30 minutes;
3)Open the transfusion valve between extractor and outer circulation inspissator, so that the extract in extractor is entered by valve outer Circulation inspissator, is then turned on the steam heating of outer circulation inspissator, makes the vaporized alcohol in extract and return to extractor, lead to Cross extractor condenser and be condensed into liquid and be back to extractor, in extractor, the root of kudzu vine effective ingredient of dissolution is constantly extracted simultaneously Liquid band is to outer circulation inspissator;In extraction process, adjust transfusion valve opening be 1/3rd at, extractor steam heating pressure Power is maintained at 0.2MPa, inspissator steam heated pressure is maintained at 0.08MPa, condenser cooling water pressure is maintained at 0.3MPa, makes In extractor, material is all flooded by alcohol liquid in extraction process, inspissator liquid level is maintained at visor 1/2nd, steaming Vapour heating amount such as does not increase at VLE, sealing and circulating 3 hours in this case;
4)Open the condenser of outer circulation inspissator, close steam heating and the condenser of extractor, by the extraction in extractor Liquid constantly puts into outer circulation inspissator, starts simultaneously at recovered alcohol, and the temperature in outer circulation inspissator is maintained at 73 ~ 78 DEG C; After the extract in extractor all discharges, the vaporized alcohol remaining in pueraria root residue is gone out and reclaims, when in extract and When alcohol concentration in slag is less than 40%, stop recovered alcohol;
5)Pueraria root residue is discharged, extract is concentrated in vacuo, keep vacuum in -0.07MPa, temperature 60 C, be concentrated into proportion For 1.2, receive cream, condensed cream be uniformly laid on baking tray, each baking tray lays 4 kilograms, and baking tray is placed on the grill of rotation, Carry out microwave drying under the conditions of keeping vacuum -0.07MPa, temperature 60 C, be dried to rewinding during moisture 5%;Then by drying Condensed cream with pulverizer pulverize, sieve, obtain the kudzu root extract that granularity is 80 mesh.
The preparation of Rhizoma Phragmitis extract:
1)Reed rhizome section is weighed and puts in extractor, add the drinking water of 6 times amount, soak 2 hours;
2)Open extractor condenser and steam heating, in tank to be extracted temperature reach 93 DEG C, seethe with excitement in tank, water vapour condensation When liquid is back in tank, keeps the temperature at 93 ~ 96 DEG C and boil and carry 30 minutes;
3)Open the transfusion valve between extractor and outer circulation inspissator, so that the extract in extractor is entered by valve outer Circulation inspissator, is then turned on the steam heating of outer circulation inspissator, then makes water evaporation therein become to steam using steam heating Vapour simultaneously returns to extractor, is condensed into liquid by extractor condenser and is back in extractor, simultaneously in extractor dissolution reed Root effective ingredient is constantly extracted liquid band to outer circulation inspissator;In extraction process, adjust transfusion valve opening be three/ At one, extractor steam heated pressure is maintained at 0.2MPa, inspissator steam heated pressure is maintained at 0.08MPa, condenser is cold But hydraulic pressure is maintained at 0.3MPa, so that material in extractor is all flooded by alcohol liquid in extraction process, inspissator liquid level is protected Hold at visor 1/2nd, VLE, sealing and circulating 3 hours in this case such as steam heating amount does not increase;
4)Open outer circulation and concentrate condenser, close steam heating and the condenser of extractor, by the extract in extractor not Break and put into outer circulation inspissator, until the extract in extractor all discharges;
5)By reed rhizome slag discharge, extract start concentrated in vacuo, keep vacuum in -0.07MPa, temperature 60 C, be concentrated into ratio It is 1.2 again, receives cream, condensed cream is uniformly laid on baking tray, each baking tray lays 4 kilograms, baking tray is placed on the grill of rotation On, carry out microwave drying under the conditions of keeping vacuum -0.07MPa, temperature 60 C, be dried to rewinding during moisture 5%;Then will do Dry reed rhizome cream, is pulverized with pulverizer, sieves, obtain the Rhizoma Phragmitis extract that granularity is 80 mesh.
The preparation method of flower of Radix Puerariae Ultramicro-powder:It is 80 mesh that flower of Radix Puerariae pulverizer is crushed to granularity, obtains flower of Radix Puerariae thin Powder, then flower of Radix Puerariae fine powder is intermittently added in micronizer, keeps rotating speed in 200 turns/mir, grinds rail pressure power in 2kgf/ cm2, air quantity is in 900m3/ h, carries out ultramicro grinding, obtains the flower of Radix Puerariae Ultramicro-powder that granularity is 200 mesh.
The preparation method of emblic fine powder:
1)It is maintained at 15 revs/min by after wild fresh fruit of fructus phyllanthi rejecting decayed fruit, impurity using drum-type fruit washing machine, cylinder rotating speed, Water spray flow 5m3/ h, charging rate is maintained at 8 kg/minute, obtains the fresh fruit cleaning up, and described water is drinking water;
2)Using fruit crusher, charging rate is maintained at 5 kg/minute, and the fresh fruit cleaning up is broken for granularity 2mm Particle;
3)Using fruit pressafiner, rotating speed is maintained at 60 revs/min, and particle is at the uniform velocity added, and it is public that charging rate is maintained at 3 Jin/minute, pomace is discharged, and underflow fruit juice flows out from bottom through filter screen;
4)Using centrifuge, drum speed is maintained at 1000 revs/min, by step 3)The underflow fruit juice obtaining at the uniform velocity adds, and enters Material speed is maintained at 0.2m3/ minute, the slag discharge isolated, obtain fruit juice clear liquid;
5)By step 4)The fruit juice clear liquid of gained is spray-dried, and high speed centrifugal atomization device rotating speed is maintained at 6000 revs/min, Adjust the air flow rate proportioning of air-supply and air inducing, so that spraying system is maintained between negative pressure 50Pa, tower top inlet temperature is maintained at 230 DEG C, bottom of towe outlet temperature is maintained at 110 DEG C, 10 beats/min of pulse rapping, stablizes screw pump feed rate in 80L/ minute, connects Continue and be spray-dried, obtain the emblic fine powder that granularity is 200 mesh.
The preparation method of the tablet of composition:
1)Take kudzu root extract 50kg(59.53%), Rhizoma Phragmitis extract 19.32kg(23%), flower of Radix Puerariae Ultramicro-powder 8 kg (9.52%), honey 3.8 kg(4.52%), emblic fine powder 2.1kg(2.5%), weigh accurately;2)Start double oar mixers, By step 1)The material equal proportion of middle weighing adds in mixer in three times, after adding, mixer positive and negative operating mixing 4 times, often Secondary mixing 10 minutes, uniform discharge after mixing, obtain composition;3)Described composition mixture material is added waving of operating In grain machine, make wet granular, standby;4)Wet granular sanitation-grade stainless steel baking tray is installed, often 2 kilograms of disk, be uniformly paved with disk Face, puts in vacuum drying chamber, airtight chamber door, opens vacuum to -0.065MPa, slowly opens steam, temperature control at 60 DEG C, Be dried 2 hours to moisture be less than 7% when discharging, standby;5)Dried material particles add in pelletizing machine, filter out particle Particle of uniform size, standby;6)Whole grain good particle rotary pelleting machine compressing tablet, standard circular piece, piece weight 0.5g, slice, thin piece mistake Interior bag is treated in sieve polishing;7)After the tablet pressing carries out irradiation sterilization, bottled with bottling machine, 100 every bottle.
Case 1:Open XX, man, 49 years old, certain company executive vice president, because the activity of frequent hardworking company business and company produce warp Battalion's management practices, dinner party is many, after drinking, often feels like fatigue, dizzy, has palpitation, in August, 2015, the items of Hospital Physical Examination Index is as follows:
First, heart rate:70 times per minute, blood pressure:Systolic pressure 110mmHg, diastolic pressure 80 mmHg
2nd, blood fat:
T-CHOL:5.52 mmol/L (2.8~5 .17mmol/L)
Triglycerides:1.75 mmol/L (0 .56~1.7mmol/L)
Cholesterol ester:5.17 mmol/L(2 .8~5.17mmol/L)
HDL:1.10 mmol/L(0.96~1.15mmol/L), low-density lipoprotein:2.52 mmol/L(0~ 3.1mmol/L)
3rd, blood sugar:Empty stomach whole blood blood sugar is 6.5 mmol/L(3.9~6.1 mmol/L), plasma glucose is 7.3 mmol/L (3.9~6.9 mmol/L)
4th, liver function:
Glutamic-pyruvic transaminase(ALT):41.3 U/L(0~40 U/L)
Glutamic-oxalacetic transaminease(AST):36 U/L(0~37 U/L)
Glutamine transferase(GGT):30.2 U/L( 7~32 U/L)
Alkaline phosphatase(ALP):87 U/L(53~128 U/L)
Total bilirubin(TBILI):19.1 umol/L(5.1~19.0 umol/L)
Bilirubin direct(DBILI):5.1 umol/L(0.0~5.1 umol/L)
Indirect bilirubin(IBILI):11.7 umol/L(5.0~12.0 umol/L)
Total protein(TP):75.4 g/L(60~80 g/L)
Glucose(GLU):5.98 mmol/L (3.89~6.11 mmol/L)
5th, kidney work(:
Urea nitrogen(BUN):8.2 mmol/L(1.7~8.3 mmol/L)
Serum creatinine(CRE):100 umol/L(53~108 umol/L)
Uric acid(UA):536 umol/L(202~416 umol/L)
Plasma wrea:7.0(3.2~7.0mmol/L)
Urine proteins:Negative
From above health check-up index, major part is all higher or exceeded, therefore has above-mentioned symptom.
Open when XX treats with courtesy every time and adhere to taking the Gegen tablets 4 that the embodiment of the present invention 1 prepares, after taking, every time should Fulfilling, it is clearheaded to drink, resourceful.Dinner party business achieves good result, in the case that other colleagues go bankrupt one after another, is Company has won a lot of clients, and the company production and operation of making are continued to, and solves the problem of employment of our company people more than 50. In July, 2016, done health check-up, index is as follows again:
First, heart rate:75 times per minute, blood pressure:Systolic pressure 100mmHg, diastolic pressure 75 mmHg
2nd, blood fat:
T-CHOL:4.14 mmol/L (2.8~5 .17mmol/L)
Triglycerides:0.93 mmol/L (0 .56~1.7mmol/L)
Cholesterol ester:3.75 mmol/L(2 .8~5.17mmol/L)
HDL:0.99 mmol/L(0.96~1.15mmol/L), low-density lipoprotein:2.31 mmol/L(0~ 3.1mmol/L)
3rd, blood sugar:Empty stomach whole blood blood sugar is 5.3 mmol/L(3.9~6.1 mmol/L), plasma glucose is 6.1mmol/L(3.9 ~6.9 mmol/L)
4th, liver function:
Glutamic-pyruvic transaminase(ALT):32.5U/L(0~40 U/L)
Glutamic-oxalacetic transaminease(AST):25U/L(0~37 U/L)
Glutamine transferase(GGT):20.1U/L(7~32 U/L)
Alkaline phosphatase(ALP):82 U/L(53~128 U/L)
Total bilirubin(TBILI):11.6 umol/L(5.1~19.0 umol/L)
Bilirubin direct(DBILI):3.5 umol/L( 0.0~5.1 umol/L)
Indirect bilirubin(IBILI):8.8umol/L(5.0~12.0 umol/L)
Total protein(TP):72.7g/L(60~80 g/L)
Glucose(GLU):5.76 mmol/L (3.89~6.11 mmol/L)
5th, kidney work(:
Urea nitrogen(BUN):3.7 mmol/L(1.7~8.3 mmol/L)
Serum creatinine(CRE):71umol/L(53~108 umol/L)
Uric acid(UA):473 umol/L(202~416 umol/L)
Plasma wrea:4.2 umol/L(3.2~7.0mmol/L)
Urine proteins:Negative
From above health check-up index, in addition to uric acid is still exceeded(But in continuous decrease), major part all refers in acceptability limit Mark optimizes very much.
Embodiment 2
The preparation of kudzu root extract:
1)Root of kudzu vine dry plate is weighed and puts in extractor, the concentration of addition 8 times amount is 70% edible alcohol, soaks 6 hours;
2)Open the condenser of extractor and steam heating, in tank to be extracted temperature reach 75 DEG C, seethe with excitement in tank, alcohol steam When condensate liquid is back in tank, the temperature in extractor is maintained at 73 ~ 78 DEG C boils and carry 30 minutes;
3)Open the transfusion valve between extractor and outer circulation inspissator, so that the extract in extractor is entered by valve outer Circulation inspissator, is then turned on the steam heating of outer circulation inspissator, makes the vaporized alcohol in extract and return to extractor, lead to Cross extractor condenser and be condensed into liquid and be back to extractor, in extractor, the root of kudzu vine effective ingredient of dissolution is constantly extracted simultaneously Liquid band is to outer circulation inspissator;In extraction process, adjust transfusion valve opening be 1/3rd at, extractor steam heating pressure Power is maintained at 0.25MPa, inspissator steam heated pressure is maintained at 0.1MPa, condenser cooling water pressure is maintained at 0.4MPa, makes In extractor, material is all flooded by alcohol liquid in extraction process, inspissator liquid level is maintained at visor 1/2nd, steaming Vapour heating amount such as does not increase at VLE, sealing and circulating 3 hours in this case;
4)Open the condenser of outer circulation inspissator, close steam heating and the condenser of extractor, by the extraction in extractor Liquid constantly puts into outer circulation inspissator, starts simultaneously at recovered alcohol, and the temperature in outer circulation inspissator is maintained at 73 ~ 78 DEG C; After the extract in extractor all discharges, the vaporized alcohol remaining in pueraria root residue is gone out and reclaims, when in extract and When alcohol concentration in slag is less than 40%, stop recovered alcohol;
5)Pueraria root residue is discharged, extract is concentrated in vacuo, keep vacuum in 65 DEG C of -0.075MPa, temperature, be concentrated into proportion For 1.25, receive cream, condensed cream is uniformly laid on baking tray, each baking tray lays 4 kilograms, baking tray is placed on the grill of rotation On, carry out microwave drying under the conditions of keeping vacuum -0.075MPa, 65 DEG C of temperature, be dried to rewinding during moisture 5.5%;Then The condensed cream being dried is pulverized with pulverizer, sieves, obtain the kudzu root extract that granularity is 120 mesh.
The preparation of Rhizoma Phragmitis extract:
1)Reed rhizome section is weighed and puts in extractor, add the drinking water of 8 times amount, soak 3 hours;
2)Open extractor condenser and steam heating, in tank to be extracted temperature reach 93 DEG C, seethe with excitement in tank, water vapour condensation When liquid is back in tank, keeps the temperature at 93 ~ 96 DEG C and boil and carry 30 minutes;
3)Open the transfusion valve between extractor and outer circulation inspissator, so that the extract in extractor is entered by valve outer Circulation inspissator, is then turned on the steam heating of outer circulation inspissator, then makes water evaporation therein become to steam using steam heating Vapour simultaneously returns to extractor, is condensed into liquid by extractor condenser and is back in extractor, simultaneously in extractor dissolution reed Root effective ingredient is constantly extracted liquid band to outer circulation inspissator;In extraction process, adjust transfusion valve opening be three/ At one, extractor steam heated pressure is maintained at 0.25MPa, inspissator steam heated pressure is maintained at 0.1MPa, condenser is cold But hydraulic pressure be maintained at 0.4MPa it is ensured that in extractor material all flooded by alcohol liquid in extraction process, inspissator liquid level Be maintained at visor 1/2nd, VLE, sealing and circulating 3 hours in this case such as steam heating amount does not increase;
4)Open outer circulation and concentrate condenser, close steam heating and the condenser of extractor, by the extract in extractor not Break and put into outer circulation inspissator, until the extract in extractor all discharges;
5)Reed rhizome slag is discharged, extract starts concentrated in vacuo, keeps vacuum in 65 DEG C of -0.075MPa, temperature, is concentrated into ratio It is 1.25 again, receives cream, condensed cream is uniformly laid on baking tray, each baking tray lays 4 kilograms, baking tray is placed on the grill of rotation On, carry out microwave drying under the conditions of keeping vacuum -0.075MPa, 65 DEG C of temperature, be dried to rewinding during moisture 5.5%;Then The reed rhizome cream that will be dried, is pulverized with pulverizer, sieves, obtain the Rhizoma Phragmitis extract that granularity is 120 mesh.
The preparation method of flower of Radix Puerariae Ultramicro-powder:It is 120 mesh that flower of Radix Puerariae pulverizer is crushed to granularity, obtains flower of Radix Puerariae Fine powder, then flower of Radix Puerariae fine powder is intermittently added in micronizer, keeps rotating speed to exist in 300 turns/mir, stone roller rail pressure power 2.5kgf/cm2, air quantity is in 1300m3/ h, carries out ultramicro grinding, obtains the flower of Radix Puerariae Ultramicro-powder that granularity is 250 mesh.
The preparation method of emblic fine powder:
1)It is maintained at 20 revs/min by after wild fresh fruit of fructus phyllanthi rejecting decayed fruit, impurity using drum-type fruit washing machine, cylinder rotating speed, Water spray flow 10m3/ h, charging rate is maintained at 10 kg/minute, obtains the fresh fruit cleaning up, and described water is to drink Water;
2)Using fruit crusher, charging rate is maintained at 8 kg/minute, and the fresh fruit cleaning up is broken for granularity 5mm Particle;
3)Using fruit pressafiner, rotating speed is maintained at 70 revs/min, and particle is at the uniform velocity added, and it is public that charging rate is maintained at 5 Jin/minute, pomace is discharged, and underflow fruit juice flows out from bottom through filter screen;
4)Using centrifuge, drum speed is maintained at 1500 revs/min, by step 3)The underflow fruit juice obtaining at the uniform velocity adds, and enters Material speed is maintained at 0.5 m3/ minute, the slag discharge isolated, obtain fruit juice clear liquid;
5)By step 4)The fruit juice clear liquid of gained is spray-dried, and high speed centrifugal atomization device rotating speed is maintained at 6500 revs/min, Adjust the air flow rate proportioning of air-supply and air inducing, so that spraying system is maintained between negative pressure 200Pa, tower top inlet temperature is maintained at 240 DEG C, bottom of towe outlet temperature is maintained at 120 DEG C, 10 beats/min of pulse rapping, stablizes screw pump feed rate in 100L/ minute, connects Continue and be spray-dried, obtain the emblic fine powder that granularity is 300 mesh.
The preparation method of the tablet of composition:
1)Take kudzu root extract 50.2kg(59.76%), Rhizoma Phragmitis extract 19.5kg(23.2%), flower of Radix Puerariae Ultramicro-powder 8.2 kg (9.76%), honey 3.9 kg(4.64%), emblic fine powder 2.22kg(2.64%), weigh accurately;2)Start double oar mixing Machine, by step 1)The material equal proportion of middle weighing adds in mixer in three times, after adding, mixer positive and negative operating mixing 4 times, Mixing 15 minutes, uniform discharge after mixing, obtain composition every time;3)Described composition mixture material is added waving of operating In granulator, make wet granular, standby;4)Wet granular sanitation-grade stainless steel baking tray is installed, often 2 kilograms of disk, are uniformly paved with Card, puts in vacuum drying chamber, airtight chamber door, opens vacuum to -0.075MPa, slowly opens steam, and temperature control is 65 DEG C, drying 2.5 hours, discharging when drying to moisture is less than 7%, standby;5)Dried material particles add in pelletizing machine, Filter out the particle of even particle size, standby;6)Whole grain good particle rotary pelleting machine compressing tablet, standard circular piece, piece weight 0.5g, interior bag is treated in slice, thin piece polishing of sieving;7)After the tablet pressing carries out irradiation sterilization, bottled with bottling machine, 100 every bottle.
Case 2:King XX, man, 45 years old, certain company product manager, because being not good at drinking, a lot of business cannot be handled, and 2015 Year August, the indices of Hospital Physical Examination are as follows:
First, heart rate:65 times per minute, blood pressure:Systolic pressure 80mmHg, diastolic pressure 65mmHg
2nd, blood fat:
T-CHOL:6.12 mmol/L (2.8~5 .17mmol/L)
Triglycerides:2.1 mmol/L (0 .56~1.7mmol/L)
Cholesterol ester:5.8 mmol/L(2 .8~5.17mmol/L)
HDL:1.15 mmol/L(0.96~1.15mmol/L), low-density lipoprotein:3.7 mmol/L(0~ 3.1mmol/L)
3rd, blood sugar:Empty stomach whole blood blood sugar is 5.5 mmol/L(3.9~6.1 mmol/L), plasma glucose is 6.0 mmol/L (3.9~6.9 mmol/L)
4th, liver function:
Glutamic-pyruvic transaminase(ALT):39 U/L(0~40 U/L)
Glutamic-oxalacetic transaminease(AST):34U/L(0~37 U/L)
Glutamyl transferase(GGT):15U/L(7~32 U/L)
Alkaline phosphatase(ALP):61U/L(53~128 U/L)
Total bilirubin(TBILI):9.2 umol/L(5.1~19.0 umol/L)
Bilirubin direct(DBILI):3.3 umol/L( 0.0~5.1 umol/L)
Indirect bilirubin(IBILI):7.6 umol/L(5.0~12.0 umol/L)
Total protein(TP):69g/L(60~80 g/L)
Glucose(GLU):4.71 mmol/L (3.89~6.11 mmol/L)
5th, kidney work(:
Urea nitrogen(BUN):5.4mmol/L(1.7~8.3 mmol/L)
Serum creatinine(CRE):98 umol/L(53~108 umol/L)
Uric acid(UA):557 umol/L(202~416 umol/L)
Plasma wrea:6.1(3.2~7.0mmol/L)
Urine proteins:Negative
From above health check-up index, partly higher, blood pressure is low, and blood fat is all exceeded, and liver function is weaker, is therefore not good at drinking.
Take the embodiment of the present invention 2 during the reception of king XX each business and prepare Gegen tablets 5, business reception also can be drunk , atmosphere enliven, business handle change very smoothly, in July, 2016, done health check-up, index is as follows again:
First, heart rate:70 times per minute, blood pressure:Systolic pressure 90mmHg, diastolic pressure 75 mmHg
2nd, blood fat:
T-CHOL:3.71 mmol/L (2.8~5 .17mmol/L)
Triglycerides:0.78 mmol/L (0 .56~1.7mmol/L)
Cholesterol ester:3.83 mmol/L(2 .8~5.17mmol/L)
HDL:0.97 mmol/L(0.96~1.15mmol/L), low-density lipoprotein:2.81 mmol/L(0~ 3.1mmol/L)
3rd, blood sugar:Empty stomach whole blood blood sugar is 5.1 mmol/L(3.9~6.1 mmol/L), plasma glucose is 5.7mmol/L(3.9 ~6.9 mmol/L)
4th, liver function:
Glutamic-pyruvic transaminase(ALT):34.5U/L(0~40 U/L)
Glutamic-oxalacetic transaminease(AST):23U/L(0~37 U/L)
Glutamyl transferase(GGT):16.3U/L(7~32 U/L)
Alkaline phosphatase(ALP):63U/L(53~128 U/L)
Total bilirubin(TBILI):8.4 umol/L(5.1~19.0 umol/L)
Bilirubin direct(DBILI):3.5umol/L(0.0~5.1 umol/L)
Indirect bilirubin(IBILI):7.3umol/L(5.0~12.0 umol/L)
Total protein(TP):72.1g/L(60~80 g/L)
Glucose(GLU):5.06 mmol/L (3.89~6.11 mmol/L)
5th, kidney work(:
Urea nitrogen(BUN):3.68 mmol/L(1.7~8.3 mmol/L)
Serum creatinine(CRE):70.2umol/L(53~108 umol/L)
Uric acid(UA):456 umol/L(202~416 umol/L)
Plasma wrea:4.7 umol/L(3.2~7.0mmol/L)
Urine proteins:Negative
From above health check-up index, in addition to uric acid is still exceeded, blood pressure, blood fat are all qualified, and majority parameters are all qualified In the range of, liver function strengthens.So capacity for liquor increases.
Embodiment 3
The preparation of kudzu root extract:
Outsourcing root of kudzu vine dry plate qualified for quality inspection is weighed and puts in extractor, the concentration of addition 6 times amount is 75% edible wine Essence, soaks 8 hours.Open extractor condenser recirculated cooling water, open the heating of extractor steam, treat that temperature reaches 75 DEG C, tank Inside seethe with excitement, when alcohol steam condensate liquid is back in tank, temperature is maintained at 73 ~ 78 DEG C individually boils and carries 30 minutes.Open and extract Tank connection outer circulation inspissator transfusion valve, opens the valve that outer circulation inspissator boil-off gas connect extractor condenser simultaneously Door, opens outer circulation inspissator heating steam, makes the vaporized alcohol that extractor conveys in the alcohol extract coming become steam to extractor Condenser, is condensed into liquid by extractor condenser and is back in extractor;The root of kudzu vine effective ingredient of dissolution in extractor is not Break and carried to inspissator by alcohol liquid in time.Adjust transfusion valve opening, extractor and inspissator steam heating amount, cooling water Amount it is ensured that in extractor material all flooded by alcohol liquid in extraction process, inspissator liquid level be maintained at visor two/ At one, steam heating amount VLE, airtight dynamic circulation 3 hours in this case such as do not increase.Then open outer circulation dense Contracting condenser connecting valve and outer circulation concentrate condenser recirculated cooling water, close extractor steam and connect extractor condenser Valve, the extract part in extractor is put into storage tank and keeps in, another part constantly puts into outer circulation inspissator, opens gas and steams Vapour heating recovery alcohol, temperature is maintained at 73 ~ 78 DEG C, and tapping and recovered alcohol are carried out simultaneously.When the liquid in extractor is whole After discharging, open extractor inner bottom part steam 2 hours, temperature is maintained at 73 ~ 78 DEG C, will remain in the vaporized alcohol in pueraria root residue Go out to extracting and reclaim after condenser condensation, the recovery of alcohol in alcohol and extract in pueraria root residue is carried out simultaneously.In extract and When the alcohol concentration reclaiming in slag is less than 40%, stop recovered alcohol.Slag discharges, and extract starts concentrated in vacuo, holding vacuum In 62 DEG C of -0.072 MPa, temperature, after liquid all adds, be concentrated into proportion is 1.2 to degree, receives cream.Condensed cream is uniformly laid on On baking tray, each baking tray lays 4 kilograms, and each baking tray is placed on the grill of rotation, keeps vacuum -0.072MPa, temperature 602 Carry out microwave drying under the conditions of DEG C, be dried to rewinding during moisture 5.2%.The root of kudzu vine alcohol cream being dried is omnipotent with 5.5KW stainless steel Pulverizer is pulverized, and sieves, obtains the kudzu root extract that granularity is 100 mesh.
The preparation of flower of Radix Puerariae Ultramicro-powder:Outsourcing flower of Radix Puerariae qualified for quality inspection is weighed, with 5.5KW stainless steel Universalpulverizer Pulverize, cross 100 mesh sieves, obtain the flower of Radix Puerariae fine powder that granularity is 100 mesh, then flower of Radix Puerariae fine powder is intermittently added 13.6KW ultra micro In the pulverizing chamber of pulverizer, keep rotating speed in 250 turns/mir, grind rail pressure power in 2.2kgf/cm2, air quantity in 1000m3/ h Under carry out ultramicro grinding operation, with powder collector splicing bucket receive powder, obtain the flower of Radix Puerariae Ultramicro-powder that granularity is 220 mesh.
The preparation of Rhizoma Phragmitis extract:
Outsourcing reed rhizome section qualified for quality inspection is weighed and puts in extractor, add the drinking water of 6 times amount, soak 2 hours.Open Extractor condenser recirculated cooling water, opens the heating of extractor steam, treat temperature reach 93 DEG C, seethe with excitement in tank, water vapour cold When lime set is back in tank, temperature is maintained at 93 ~ 96 DEG C individually boils and carries 30 minutes.Open extractor connection outer circulation inspissator defeated Fluid valve, opens the valve that outer circulation inspissator boil-off gas connect extractor condenser simultaneously, opens outer circulation inspissator and adds Vapours, makes the water evaporation that extractor conveys in the Aqueous extracts coming become steam to extractor condenser, by extractor condenser It is condensed into liquid to be back in extractor;The reed rhizome effective ingredient of dissolution in extractor is constantly carried to inspissator by liquid in time Interior.Adjust transfusion valve opening, extractor and inspissator steam heating amount, cooling water inflow it is ensured that in extractor material extracting All flooded by alcohol liquid in journey, the vapour-liquid such as inspissator liquid level is maintained at visor 1/2nd, steam heating amount does not increase Balance, airtight dynamic circulation 3 hours in this case.Then open outer circulation and concentrate condenser connecting valve and outer circulation concentration Condenser recirculated cooling water, closes extractor steam and connects extractor condenser valve, by the extract in extractor one Point put into storage tank to keep in, another part constantly puts into outer circulation inspissator.After liquid discharges, slag discharges, and extract starts vacuum Concentrate, keep vacuum in 62 DEG C of -0.072MPa, temperature, after liquid all adds, being concentrated into proportion is 1.25, receives cream.Concentrate Cream is uniformly laid on baking tray, and each baking tray lays 4 kilograms, and each baking tray is placed on the grill of rotation, and holding vacuum- Carry out microwave drying under the conditions of 0.072MPa, 62 DEG C of temperature, be dried to rewinding during moisture 5%.The reed rhizome cream being dried, uses 5.5KW Stainless steel Universalpulverizer is pulverized, and crosses 100 mesh sieves, obtains the Rhizoma Phragmitis extract that granularity is 100 mesh.
The preparation of emblic fine powder:
Add weighing after outsourcing wild fresh fruit of fructus phyllanthi rejecting decayed fruit qualified for quality inspection, impurity in stainless steel high position hopper, open Open 5KW drum-type fruit washing machine, open and drink water sprinkler system, after working well, cylinder rotating speed is maintained at 18 revs/min, Water spray Flow 8m3/ h fresh fruit of fructus phyllanthi is at the uniform velocity really continuously added to rotation, in the fruit washing machine helix drum of spray water, side's continuous feed, The opposing party's continuous discharge, charging rate is maintained at 9 kg/minute, and the fresh fruit of wash clean rises to stainless steel height through conveyer belt Store in the hopper of position;Start 5.5KW fruit crusher, the fresh fruit cleaning up at the uniform velocity adds, it is public that charging rate is maintained at 6 Jin/minute, fresh fruit is broken for the particle of granularity 4mm, rises in stainless steel high position hopper through conveyer belt and stores;Start 7.5KW fruit pressafiner, rotating speed is maintained at 65 revs/min, particle is at the uniform velocity added, and charging rate is maintained at 4 kilograms/point Clock, pomace is discharged from other end discharging, and fruit juice flows out from bottom through filter screen, is pumped into the storage of stainless steel head tank through food-grade underflow Deposit;Start 10KW automatic discharge centrifuge, drum speed is maintained at 1200 revs/min, underflow fruit juice is at the uniform velocity added, charging Speed is maintained at 0.4 m3/ minute, the slag discharge isolated, fruit juice clear liquid fruit juice pump is delivered to stainless steel storage tank and keeps in;According to The systems such as secondary startup 120KW spray drying tower air-supply, air inducing, heating, pulse rapping, high speed centrifugation atomization, drinking water is through spiral shell Bar is pumped into high speed centrifugal atomization device, the debugging each parameter of spraying system it is ensured that high speed centrifugal atomization device rotating speed be maintained at 6200 turns/ Minute, adjust the air flow rate proportionings such as air-supply, air inducing, so that spraying system is maintained between negative pressure 100Pa, tower top inlet temperature is maintained at 235 DEG C, bottom of towe outlet temperature is maintained at 115 DEG C, and 10 beats/min of pulse rapping stablizes screw pump feed rate in 90L/ minute, Guarantee water spraying atomization all can steam raising 30 minutes, water spray will be entered and change charging fruit juice spraying into, under these conditions continuously Carry out fruit juice spray drying, per hour in clean area powder collector rewinding once, obtain the emblic fine powder that granularity is 250 mesh.
The preparation of composition:
1)Weigh:Weigh kudzu root extract 50.3kg(59.88%), Rhizoma Phragmitis extract 19.5kg(23.2%), flower of Radix Puerariae ultra micro Powder 8.15 kg(9.66%), honey 3.9 kg(4.64%), emblic fine powder 2.2kg(2.62%), weigh accurately, standby;
2)Mixing:By step 1)The material equal proportion of middle weighing adds in double oar mixers of operating, positive and negative operating mixed processing 4 Secondary, mixing 12 minutes, mix discharging, obtain composition every time.
The auxiliary material pharmaceutically accepting is added to be prepared into capsule in described composition.
Case 3:Liu XX, man, 36 years old, portion of Ren company quality handle, smell alcohol smell will headache and dizzy, 2015 8 The indices of month Hospital Physical Examination are as follows:
First, heart rate:70 times per minute, blood pressure:Systolic pressure 110mmHg, diastolic pressure 80 mmHg
2nd, blood fat:
T-CHOL:5.52 mmol/L (2.8~5 .17mmol/L)
Triglycerides:1.73 mmol/L (0 .56~1.7mmol/L)
Cholesterol ester:5.19 mmol/L(2 .8~5.17mmol/L)
HDL:1.10 mmol/L(0.96~1.15mmol/L), low-density lipoprotein:2.52 mmol/L(0~ 3.1mmol/L)
3rd, blood sugar:Empty stomach whole blood blood sugar is 6.5 mmol/L(3.9~6.1 mmol/L), plasma glucose is 7.3 mmol/L (3.9~6.9 mmol/L)
4th, liver function:
Glutamic-pyruvic transaminase(ALT):40.3 U/L(0~40 U/L)
Glutamic-oxalacetic transaminease(AST):34 U/L(0~37 U/L)
Glutamyl transferase(GGT):30.2 U/L( 7~32 U/L)
Alkaline phosphatase(ALP):87 U/L( 53~128 U/L)
Total bilirubin(TBILI):19.1 umol/L(5.1~19.0 umol/L)
Bilirubin direct(DBILI):4.8 umol/L( 0.0~5.1 umol/L)
Indirect bilirubin(IBILI):11.7 umol/L(5.0~12.0 umol/L)
Total protein(TP):75.4 g/L(60~80 g/L)
Glucose(GLU):5.98 mmol/L (3.89~6.11 mmol/L)
5th, kidney work(:
Urea nitrogen(BUN):8.2 mmol/L(1.7~8.3 mmol/L)
Serum creatinine(CRE):100 umol/L(53~108 umol/L)
Uric acid(UA):536 umol/L(202~416 umol/L)
Plasma wrea:7.0(3.2~7.0mmol/L)
Urine proteins:Negative
From above health check-up index, major part is all higher or exceeded, therefore has above-mentioned symptom.Liu XX adheres to taking this daily The capsule that inventive embodiments 3 prepare 4, does experiment and smells the sensation that alcohol smell does not have headache and dizzy yet during taking. In July, 2016, done health check-up, index is as follows again:
First, heart rate:70 times per minute, blood pressure:Systolic pressure 90mmHg, diastolic pressure 75 mmHg
2nd, blood fat:
T-CHOL:3.71 mmol/L (2.8~5 .17mmol/L)
Triglycerides:0.82 mmol/L (0 .56~1.7mmol/L)
Cholesterol ester:4.83 mmol/L(2 .8~5.17mmol/L)
HDL:0.99 mmol/L(0.96~1.15mmol/L), low-density lipoprotein:2.81 mmol/L(0~ 3.1mmol/L)
3rd, blood sugar:Empty stomach whole blood blood sugar is 5.0mmol/L(3.9~6.1 mmol/L), plasma glucose is 5.7mmol/L(3.9 ~6.9 mmol/L)
4th, liver function:
Glutamic-pyruvic transaminase(ALT):34.5U/L(0~40 U/L)
Glutamic-oxalacetic transaminease(AST):23U/L(0~37 U/L)
Glutamyl transferase(GGT):18.3U/L( 7~32 U/L)
Alkaline phosphatase(ALP):62U/L( 53~128 U/L)
Total bilirubin(TBILI):8.4 umol/L(5.1~19.0 umol/L)
Bilirubin direct(DBILI):3.5umol/L( 0.0~5.1 umol/L)
Indirect bilirubin(IBILI):9.3umol/L(5.0~12.0 umol/L)
Total protein(TP):72.1g/L(60~80 g/L)
Glucose(GLU):5.06 mmol/L (3.89~6.11 mmol/L)
5th, kidney work(:
Urea nitrogen(BUN):3.68 mmol/L(1.7~8.3 mmol/L)
Serum creatinine(CRE):70.2umol/L(53~108 umol/L)
Uric acid(UA):415 umol/L(202~416 umol/L)
Plasma wrea:4.7 umol/L(3.2~7.0mmol/L)
Urine proteins:Negative
From above health check-up index, all qualified.Liver function significantly increases, so not being afraid of alcohol.
Embodiment 4
The preparation of composition:
1)Weigh kudzu root extract 50.2kg(59.76%), Rhizoma Phragmitis extract 18.5kg(22.02%), flower of Radix Puerariae Ultramicro-powder 8.4kg(10%), honey 4 kg(4.76%), emblic fine powder 2.91kg(3.46%), weigh accurately, standby;
2)Start double oar mixers, the material weighing equal proportion is added in mixer in three times, after adding, the positive and negative fortune of mixer Turn mixing four times, mixing 10 minutes, uniform discharge after mixing, obtain composition every time.
The auxiliary material pharmaceutically accepting is added to be prepared into powder in described composition.
Case 4:What XX, female, 42 years old, certain corporate office chief of the office, because of business dinner party, frequent dizziness headache, what XX is each Business dinner party adheres to that taking the embodiment of the present invention 4 prepares root of kudzu vine powder, and after 10 months, no dizziness headache there occurs substantially.
Embodiment 5
The preparation of composition:
1)Weigh kudzu root extract 50.4kg(60%), Rhizoma Phragmitis extract 19.5kg(23.2%), flower of Radix Puerariae Ultramicro-powder 8.2 kg (9.76%), honey 3.7 kg(4.64%), emblic fine powder 2.22kg(2.64%), weigh accurately, standby;
2)Start double oar mixers, the material weighing equal proportion is added in mixer in three times, after adding, the positive and negative fortune of mixer Turn mixing four times, mixing 15 minutes, uniform discharge after mixing, obtain composition every time.
The auxiliary material pharmaceutically accepting is added to be prepared into granule in described composition.
Case 5:Lee XX, man, 33 years old, certain company workshop director, due to often meetting with friend, often feel like dizzy head Bitterly.Lee XX adheres to that taking the embodiment of the present invention 5 prepares root of kudzu vine particle daily, and after taking 3 months, dizziness headache mitigates, 12 After month, dizziness headache disappears.
Embodiment 6
The preparation of composition:
1)Weigh kudzu root extract 50kg(59.53%), Rhizoma Phragmitis extract 18.5kg(22.02%), flower of Radix Puerariae Ultramicro-powder 8.4 kg(10%), honey 4.2kg(5%), emblic fine powder 2.9kg(3.45%), weigh accurately, standby;
2)Start double oar mixers, the material weighing equal proportion is added in mixer in three times, after adding, the positive and negative fortune of mixer Turn mixing four times, mixing 10 minutes, uniform discharge after mixing, obtain composition every time.
The auxiliary material pharmaceutically accepting is added to be prepared into pill in described composition.
Case 6:Zhao XX, man, 63 years old, retired professor, better at ordinary times little wine, deposit and will feel after drinking to have a headache, but no Method breaks off this slight drinking habit, decocts very much.Adhere to that taking the embodiment of the present invention 6 prepares 5, root of kudzu vine ball daily from Zhao XX, The problem not occurring again having a headache after drinking, and healthy, feel energetic.
Embodiment 7
Weigh 50 parts of kudzu root extract, 5 parts of flower of Radix Puerariae Ultramicro-powder, 11 parts of Rhizoma Phragmitis extract, 2.5 parts of honey, emblic fine powder 1.5 Part, standby;The material equal proportion weighing is added in double oar mixers of operating, positive and negative operating mixed processing 4 times, mixing every time 10 ~ 15 minutes, mix discharging, obtain composition.Described composition is in preparation prevention/auxiliary treatment solution drinks, high blood Can apply in pressure, high fat of blood similar drug or health food.
Embodiment 8
1)Weigh:Weigh 60 parts of kudzu root extract, 10 parts of flower of Radix Puerariae Ultramicro-powder, 22 parts of Rhizoma Phragmitis extract, 5 parts of honey, emblic 3 parts of fine powder, standby;
2)Mixing:By step 1)The material equal proportion of middle weighing adds in double oar mixers of operating, positive and negative operating mixed processing 4 Secondary, mixing 11 minutes, mix discharging, obtain composition every time.
Described composition is in preparation prevention/auxiliary treatment solution drinks, hypertension, high fat of blood similar drug or health food Can apply.
Embodiment 9
1)Weigh:Weigh 52 parts of kudzu root extract, 6 parts of flower of Radix Puerariae Ultramicro-powder, 15 parts of Rhizoma Phragmitis extract, 3 parts of honey, emblic essence 2 parts of powder, standby;
2)Mixing:By step 1)The material equal proportion of middle weighing adds in double oar mixers of operating, positive and negative operating mixed processing 4 Secondary, mixing 13 minutes, mix discharging, obtain composition every time.
Described composition is in preparation prevention/auxiliary treatment solution drinks, hypertension, high fat of blood similar drug or health food Can apply.
Embodiment 10
1)Weigh:Weigh 56 parts of kudzu root extract, 8 parts of flower of Radix Puerariae Ultramicro-powder, 18 parts of Rhizoma Phragmitis extract, 4 parts of honey, emblic essence 2.5 parts of powder, standby;
2)Mixing:By step 1)The material equal proportion of middle weighing adds in double oar mixers of operating, positive and negative operating mixed processing 4 Secondary, mixing 14 minutes, mix discharging, obtain composition every time.
Described composition is in preparation prevention/auxiliary treatment solution drinks, hypertension, high fat of blood similar drug or health food Can apply.

Claims (9)

1. a kind of composition is it is characterised in that include the raw material of following weight portion:50 ~ 60 parts of kudzu root extract, flower of Radix Puerariae ultra micro 5 ~ 10 parts of powder, 11 ~ 22 parts of Rhizoma Phragmitis extract, 2.5 ~ 5 parts of honey, 1.5 ~ 3 parts of emblic fine powder.
2. composition according to claim 1 is it is characterised in that the extracting method of described kudzu root extract includes:
1)Root of kudzu vine dry plate is weighed and puts in extractor, the concentration of addition 6 ~ 8 times amount is 70% ~ 75% edible alcohol, soaks 6 ~ 8 hours;
2)Open the condenser of extractor and steam heating, in tank to be extracted temperature reach 75 DEG C, seethe with excitement in tank, alcohol steam When condensate liquid is back in tank, the temperature in extractor is maintained at 73 ~ 78 DEG C boils and carry 30 minutes;
3)Open the transfusion valve between extractor and outer circulation inspissator, so that the extract in extractor is entered by valve outer Circulation inspissator, is then turned on the steam heating of outer circulation inspissator, makes the vaporized alcohol in extract and return to extractor, lead to Cross extractor condenser and be condensed into liquid and be back to extractor, in extractor, the root of kudzu vine effective ingredient of dissolution is constantly extracted simultaneously Liquid band is to outer circulation inspissator;In extraction process, adjust transfusion valve opening be 1/3rd at, extractor steam heating pressure Power is maintained at 0.2 ~ 0.25MPa, inspissator steam heated pressure is maintained at 0.08 ~ 0.1MPa, condenser cooling water pressure is maintained at 0.3 ~ 0.4MPa, sealing and circulating 3 hours in this case;
4)Open the condenser of outer circulation inspissator, close steam heating and the condenser of extractor, by the extraction in extractor Liquid constantly puts into outer circulation inspissator, starts simultaneously at recovered alcohol, and the temperature in outer circulation inspissator is maintained at 73 ~ 78 DEG C; After the extract in extractor all discharges, the vaporized alcohol remaining in pueraria root residue is gone out and reclaims, when in extract and When alcohol concentration in slag is less than 40%, stop recovered alcohol;
5)Pueraria root residue is discharged, extract is concentrated in vacuo, keep vacuum in 60 ~ 65 DEG C of -0.07 ~ -0.075MPa, temperature, Being concentrated into proportion is 1.2 ~ 1.25, receives cream, condensed cream is uniformly laid on baking tray, baking tray is placed on the grill of rotation, protects Hold vacuum -0.07 ~ -0.075MPa, carry out microwave drying under the conditions of 60 ~ 65 DEG C of temperature, be dried and receive to during moisture 5% ~ 5.5% Material;Then the condensed cream being dried is pulverized with pulverizer, sieve, obtain the kudzu root extract that granularity is 80 ~ 120 mesh.
3. composition according to claim 1 is it is characterised in that the preparation method of described flower of Radix Puerariae Ultramicro-powder is by Pueraria lobota Root flower is pulverized with pulverizer, sieves, and obtains the flower of Radix Puerariae fine powder that granularity is 80 ~ 120 mesh, is then intermittently added flower of Radix Puerariae fine powder In micronizer, keep rotating speed in 200 ~ 300 turns/mir, grind rail pressure power in 2 ~ 2.5kgf/cm2, air quantity is in 900 ~ 1300m3/ H, carries out ultramicro grinding, obtains the flower of Radix Puerariae Ultramicro-powder that granularity is 200 ~ 250 mesh.
4. composition according to claim 1 is it is characterised in that the extracting method of described Rhizoma Phragmitis extract includes:
1)Reed rhizome section is weighed and puts in extractor, add the drinking water of 6 ~ 8 times amount, soak 2 ~ 3 hours;
2)Open extractor condenser and steam heating, in tank to be extracted temperature reach 93 DEG C, seethe with excitement in tank, water vapour condensation When liquid is back in tank, keeps the temperature at 93 ~ 96 DEG C and boil and carry 30 minutes;
3)Open the transfusion valve between extractor and outer circulation inspissator, so that the extract in extractor is entered by valve outer Circulation inspissator, is then turned on the steam heating of outer circulation inspissator, then makes water evaporation therein become to steam using steam heating Vapour simultaneously returns to extractor, is condensed into liquid by extractor condenser and is back in extractor, simultaneously in extractor dissolution reed Root effective ingredient is constantly extracted liquid band to outer circulation inspissator;In extraction process, adjust transfusion valve opening be three/ At one, extractor steam heated pressure is maintained at 0.2 ~ 0.25MPa, inspissator steam heated pressure is maintained at 0.08 ~ 0.1MPa, Condenser cooling water pressure is maintained at 0.3 ~ 0.4MPa, in this case sealing and circulating 3 hours;
4)Open outer circulation and concentrate condenser, close steam heating and the condenser of extractor, by the extract in extractor not Break and put into outer circulation inspissator, until the extract in extractor all discharges;
5)By reed rhizome slag discharge, extract start concentrated in vacuo, keep vacuum in -0.07 ~ -0.075MPa, temperature 60 ~ 65 DEG C, being concentrated into proportion is 1.2 ~ 1.25, receives cream, condensed cream is uniformly laid on baking tray, baking tray is placed on the grill of rotation, Carry out microwave drying, when being dried to moisture 5% ~ 5.5% under the conditions of keeping vacuum -0.07 ~ -0.075MPa, 60 ~ 65 DEG C of temperature Rewinding;Then the reed rhizome cream being dried, is pulverized with pulverizer, sieves, and obtains the Rhizoma Phragmitis extract that granularity is 80 ~ 120 mesh.
5. composition according to claim 1 is it is characterised in that the preparation method of described emblic fine powder includes:
1)It is maintained at 15 ~ 20 revs/min by after wild fresh fruit of fructus phyllanthi rejecting decayed fruit, impurity using drum-type fruit washing machine, cylinder rotating speed Clock, Water spray flow 5 ~ 10m3/ h, charging rate is maintained at 8 ~ 10 kg/minute, obtains the fresh fruit cleaning up, described water For drinking water;
2)Using fruit crusher, charging rate is maintained at 5 ~ 8 kg/minute, by the fresh fruit cleaning up be broken for granularity 2 ~ The particle of 5mm;
3)Using fruit pressafiner, rotating speed is maintained at 60 ~ 70 revs/min, and particle is at the uniform velocity added, and charging rate is maintained at 3 ~ 5 kg/minute, pomace is discharged, and underflow fruit juice flows out from bottom through filter screen;
4)Using centrifuge, drum speed is maintained at 1000 ~ 1500 revs/min, by step 3)The underflow fruit juice obtaining at the uniform velocity adds Enter, charging rate is maintained at 0.2 ~ 0.5 m3/ minute, the slag discharge isolated, obtain fruit juice clear liquid;
5)By step 4)The fruit juice clear liquid of gained is spray-dried, high speed centrifugal atomization device rotating speed be maintained at 6000 ~ 6500 turns/ Minute, adjust the air flow rate proportioning of air-supply and air inducing, so that spraying system is maintained between negative pressure 50 ~ 200Pa, tower top inlet temperature is protected Hold at 230 ~ 240 DEG C, bottom of towe outlet temperature is maintained at 110 ~ 120 DEG C, 10 beats/min of pulse rapping, stablize screw pump feed stream Amount, in 80 ~ 100L/ minute, is carried out continuously spray drying, obtains the emblic fine powder that granularity is 200 ~ 300 mesh.
6. one kind according to the preparation method of the arbitrary described composition of claim 1 ~ 5 it is characterised in that described preparation method Including following steps:
1)Weigh:Weigh 50 ~ 60 parts of kudzu root extract, 5 ~ 10 parts of flower of Radix Puerariae Ultramicro-powder, 11 ~ 22 parts of Rhizoma Phragmitis extract, honey 2.5 ~ 5 parts, 1.5 ~ 3 parts of emblic fine powder, standby;
2)Mixing:By step 1)The material equal proportion of middle weighing adds in double oar mixers of operating in three times, and positive and negative operating is mixed Close and process 4 times, mix 10 ~ 15 minutes every time, mix discharging, obtain composition.
7. one kind according to the preparation of the arbitrary described composition of claim 1 ~ 5 it is characterised in that described preparation is described Composition in add the auxiliary material pharmaceutically accepting to be prepared into capsule, tablet, powder, granule, liquid preparation, pill.
8. composition according to claim 7 preparation it is characterised in that the preparation method of described tablet include following Step:
1)Pelletize:Described composition is added in the oscillating granulator of operating, makes wet granular, standby;
2)It is dried:Wet granular sanitation-grade stainless steel baking tray is installed, often 2 kilograms of disk, are uniformly paved with card, put into vacuum drying In case, airtight chamber door, open vacuum to -0.065 ~ -0.075MPa, slowly open steam, temperature control, at 60 ~ 65 DEG C, is dried 2 ~ 2.5 hours, discharging when drying to moisture is less than 7%, standby;
3)Whole grain:Dried material particles are added in pelletizing machine, filters out the particle of even particle size, standby;
4)Compressing tablet:Whole grain good particle rotary pelleting machine compressing tablet, makes standard circular piece, piece weight 0.5g, treats interior bag;
5)Sterilization, interior bag:After the tablet pressing is carried out disinfection, carry out bubble-cap or bottling.
9. one kind applying it is characterised in that described composition is in preparation according to the arbitrary described composition of claim 1 ~ 5 Application in prevention/auxiliary treatment solution drinks, hypertension, high fat of blood similar drug or health food.
CN201610867779.6A 2016-09-30 2016-09-30 Composition, as well as preparation method, preparation and application thereof Pending CN106418537A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610867779.6A CN106418537A (en) 2016-09-30 2016-09-30 Composition, as well as preparation method, preparation and application thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610867779.6A CN106418537A (en) 2016-09-30 2016-09-30 Composition, as well as preparation method, preparation and application thereof

Publications (1)

Publication Number Publication Date
CN106418537A true CN106418537A (en) 2017-02-22

Family

ID=58171638

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201610867779.6A Pending CN106418537A (en) 2016-09-30 2016-09-30 Composition, as well as preparation method, preparation and application thereof

Country Status (1)

Country Link
CN (1) CN106418537A (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108048289A (en) * 2018-01-19 2018-05-18 楚雄州百草岭药业发展有限公司 A kind of truffle wine and preparation method thereof
CN108096391A (en) * 2018-01-19 2018-06-01 楚雄州百草岭药业发展有限公司 A kind of composition and preparation method containing Panax Notoginseng Folium Saponins, preparation and application
CN108208854A (en) * 2018-01-19 2018-06-29 楚雄州百草岭药业发展有限公司 A kind of pueraria lobata meal replacement powder and preparation method thereof
CN109394970A (en) * 2019-01-14 2019-03-01 楚雄州百草岭药业发展有限公司 A kind of mulberry leaf composition and preparation method thereof, preparation and application
CN109497550A (en) * 2019-01-14 2019-03-22 楚雄州百草岭药业发展有限公司 A kind of siberian solomonseal rhizome composition and preparation method thereof, preparation and application

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1262074A (en) * 2000-01-24 2000-08-09 广东华怡(集团)新产品开发研究所 Process for extracting concentrated liquid from oppositeleaf fig root and preparing tea and instant soup material from same
CN1385195A (en) * 2002-06-05 2002-12-18 朱光荣 Health care formula for relieving alcoholism, dispelling alcohol effects and protecting liver
CN102835664A (en) * 2012-09-29 2012-12-26 楚雄州百草岭药业发展有限公司 Phyllanthus emblica fine powder containing high-activity superoxide dismutase and preparation method
CN103535811A (en) * 2013-10-23 2014-01-29 桂林丰润莱生物科技有限公司 Stasis removing, collaterals dredging and breast beautifying drink and preparation method thereof
CN103689731A (en) * 2012-09-27 2014-04-02 李翠平 Hangover alleviating beverage
CN104904933A (en) * 2015-05-15 2015-09-16 周新福 A liver protecting and alcohol effect dispelling health-care tea

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1262074A (en) * 2000-01-24 2000-08-09 广东华怡(集团)新产品开发研究所 Process for extracting concentrated liquid from oppositeleaf fig root and preparing tea and instant soup material from same
CN1385195A (en) * 2002-06-05 2002-12-18 朱光荣 Health care formula for relieving alcoholism, dispelling alcohol effects and protecting liver
CN103689731A (en) * 2012-09-27 2014-04-02 李翠平 Hangover alleviating beverage
CN102835664A (en) * 2012-09-29 2012-12-26 楚雄州百草岭药业发展有限公司 Phyllanthus emblica fine powder containing high-activity superoxide dismutase and preparation method
CN103535811A (en) * 2013-10-23 2014-01-29 桂林丰润莱生物科技有限公司 Stasis removing, collaterals dredging and breast beautifying drink and preparation method thereof
CN104904933A (en) * 2015-05-15 2015-09-16 周新福 A liver protecting and alcohol effect dispelling health-care tea

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108048289A (en) * 2018-01-19 2018-05-18 楚雄州百草岭药业发展有限公司 A kind of truffle wine and preparation method thereof
CN108096391A (en) * 2018-01-19 2018-06-01 楚雄州百草岭药业发展有限公司 A kind of composition and preparation method containing Panax Notoginseng Folium Saponins, preparation and application
CN108208854A (en) * 2018-01-19 2018-06-29 楚雄州百草岭药业发展有限公司 A kind of pueraria lobata meal replacement powder and preparation method thereof
CN109394970A (en) * 2019-01-14 2019-03-01 楚雄州百草岭药业发展有限公司 A kind of mulberry leaf composition and preparation method thereof, preparation and application
CN109497550A (en) * 2019-01-14 2019-03-22 楚雄州百草岭药业发展有限公司 A kind of siberian solomonseal rhizome composition and preparation method thereof, preparation and application

Similar Documents

Publication Publication Date Title
CN106418537A (en) Composition, as well as preparation method, preparation and application thereof
CN105199927B (en) A kind of Maca wine and preparation method thereof
CN105613889A (en) Preparation method of persimmon calyx and pueraria flower healthcare caffeine
CN101347216B (en) Method for preparing nutritional concentrated solution of red date
CN103875854B (en) Diaphragma juglandis instant product and preparation method thereof
CN104509629A (en) Herbal tea solid beverage and preparation method thereof
CN103750483B (en) Dendrobium officinale solid beverage and preparation method thereof
CN109394970A (en) A kind of mulberry leaf composition and preparation method thereof, preparation and application
CN106387904B (en) A kind of composition and preparation method thereof, preparation and application
CN108308475A (en) A kind of Herba Andrographitis donkey-hide gelatin health drink and preparation method thereof
CN108813026A (en) A kind of preparation process of folium cortex eucommiae wild chrysanthemum tea powder
CN102697818B (en) Honey-stuffed Chinese medicine preparation and production process thereof
CN110301609A (en) A kind of nourishing the stomach liver-protecting and alcoholism-relieving soup
CN107080027A (en) The processing method of Moringa Pueravia flower tea
CN107410583A (en) It is a kind of to treat kidney-yang deficiency on behalf of the tea
CN107136371A (en) Fine and soft mulse of the blue or green juice birch of a kind of barley and preparation method thereof
CN106852468B (en) Composition containing moringa oleifera leaf extract, and preparation method, preparation and application thereof
CN105961710A (en) Toxin-expelling slimming tea for women and preparing method thereof
CN105901463A (en) Production method of mulberry-containing beverage granules
CN110074301A (en) A kind of black garlic Chinese herbal medicine beverage and its preparation process
CN109497550A (en) A kind of siberian solomonseal rhizome composition and preparation method thereof, preparation and application
CN108096391A (en) A kind of composition and preparation method containing Panax Notoginseng Folium Saponins, preparation and application
CN107668285A (en) Eight delicacies health preserving tea
CN109288929A (en) The preparation method of compound Ganmaoling Granules
CN108096371A (en) A kind of Oral Solutions of Zinc Gluconate and preparation method thereof

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20170222

RJ01 Rejection of invention patent application after publication