CN106310137A - 一种治疗冠心病心绞痛气滞血瘀证的中药组合物 - Google Patents

一种治疗冠心病心绞痛气滞血瘀证的中药组合物 Download PDF

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CN106310137A
CN106310137A CN201610869441.4A CN201610869441A CN106310137A CN 106310137 A CN106310137 A CN 106310137A CN 201610869441 A CN201610869441 A CN 201610869441A CN 106310137 A CN106310137 A CN 106310137A
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chinese medicine
medicine composition
stagnation
rhizoma
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罗娟
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Chengdu Feilong Water Treatment Technology Institute
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Abstract

本发明属于中药制剂领域，目的是根据中医对治疗冠心病心绞痛气滞血瘀证的认识机理而提供的一种治疗冠心病心绞痛气滞血瘀证的中药组合物，所述中药组合物的各个组分及其质量份比如下：鸡血藤150～260g、丹参80～160g、当归80～160g、桃仁80～160g、赤芍60～120g、灵芝60～120g、红花50～120g、降香90～160g、郁金80～160g、益母草100～160g、三七30～100g、川芎30～100g、陈皮30～100g、木香30～100g、石菖蒲50～100g、枸杞子100～200g、酒黄精100～160g、人参30～160g、麦冬100～200g、泽泻（盐制）100～200g、冰片1.8～3.5g；本发明提供的药物是一个标本兼治的中药组方。

Description

一种治疗冠心病心绞痛气滞血瘀证的中药组合物
技术领域
本发明属于中药制剂领域，具体涉及一种治疗冠心病心绞痛气滞血瘀证的中药组合物，特别是供冠心病心绞痛气滞血瘀证患者使用的中药组合物的领域。
背景技术
医者认为：冠心病心绞痛是由于脂质代谢异常，血液粘稠度增高导致冠状动脉壁损伤、脂质沉着，冠状动脉粥样硬化使血管腔变窄、阻塞或痉挛，导致心肌急剧或暂时缺血缺氧引起的一组临床综合征。该病是心血管系统常见病、多发病，严重威胁人类生命健康。冠心病心绞痛发作时，患者面色苍白、心率快、血压高、出冷汗、表情焦虑，多发生在胸骨后及左前胸，疼痛范围为拳头或手掌大小，而且每次发作部位比较固定，发作时间一般为 1～5 分钟。用心电图检查，冠心病心绞痛发作时可出现 ST 段下移，T 波低平或倒置的现象，有的病人可完全正常。发作时病人吸氧或舌下含硝酸甘油后病情很快减轻或好转。
那么，就如何找到一种可有效治疗冠心病心绞痛气滞血瘀证的中药组合物，是我们目前急需要解决的问题。
发明内容
随着我国中医中药学的不断发展，在治疗冠心病心绞痛气滞血瘀证上，人们逐渐意识到了中医治疗冠心病心绞痛气滞血瘀证的优点，且在治疗过程中疗效好、见效快、毒副作用小等优势，针对现有西医治疗冠心病心绞痛气滞血瘀证的现状，本发明的目的是在于提供一种治疗冠心病心绞痛气滞血瘀证的中药组合物，以解决冠心病心绞痛气滞血瘀证患者早日恢复健康的问题。该药物是以常见的中药为原料，通过选择合理的药物及质量份比，可有效治疗上述冠心病心绞痛气滞血瘀证。
为达到上述发明的目的，本发明所采用的技术方案为：提供一种治疗冠心病心绞痛气滞血瘀证的中药组合物，其特征在于，所述中药组合物的各个组分及其质量份比如下所示：
鸡血藤150～260g、丹参80～160g、当归80～160g、桃仁80～160g、赤芍60～120g、灵芝60～120g、红花50～120g、降香90～160g、郁金80～160g、益母草100～160g、三七30～100g、川芎30～100g、陈皮30～100g、木香30～100g、石菖蒲50～100g、枸杞子100～200g、酒黄精100～160g、人参30～160g、麦冬100～200g、泽泻（盐制）100～200g、冰片1.8～3.5g。
一种治疗冠心病心绞痛气滞血瘀证的中药组合物，其特征在于，所述中药组合物的各个组分及其质量份比如下所示：
鸡血藤170～230g、丹参90～140g、当归90～140g、桃仁90～140g、赤芍70～105g、灵芝70～105g、红花60～105g、降香100～140g、郁金90～140g、益母草115～140g、三七40～90g、川芎40～90g、陈皮40～90g、木香40～90g、石菖蒲60～90g、枸杞子115～170g、酒黄精115～140g、人参40～140g、麦冬115～170g、泽泻（盐制）115～170g、冰片2～3.2g。
一种治疗冠心病心绞痛气滞血瘀证的中药组合物，其特征在于，所述“最佳方案”的中药组合物的各个组分及其质量份比如下所示：
鸡血藤200g、丹参120g、当归120g、桃仁120g、赤芍90g、灵芝90g、红花90g、降香120g、郁金120g、益母草120g、三七80g、川芎80g、陈皮80g、木香80g、石菖蒲80g、枸杞子150g、酒黄精120g、人参120g、麦冬150g、泽泻（盐制）150g、冰片3g。
一种治疗冠心病心绞痛气滞血瘀证的中药组合物，其特征在于，所述方法包括如下步骤制备而成：
A、将上述原料中药拣去杂质、粉尘，及干燥后，按照质量份比共研为极细末待用；
B、按照传统制备中药水丸剂的方法，将研磨好的极细末药物过筛后，放入药器中混合拌均，然后制备成水丸剂（其水丸的粒度为：4.7mm～4.8mm），进而晒干，分装密封即可。
一种治疗冠心病心绞痛气滞血瘀证的中药组合物，其特征在于，所述服用方法为：将制备好的水丸剂药物以每日二次服用，早晚各服一次，给药量2.5g /次，服药15～30天，症状逐渐减轻。
本发明组方中的各原料中药在中国药典、中国辞典以及中华本草中均有详细的记载。本发明选用其中最常见的中药为原料，充分发挥各组分的药理功效：
鸡血藤，味苦、微甘、性温，具有活血舒筋、养血调经之功效，用于治疗手足麻木、肢体瘫痪、风湿痹痛、妇女有经不调、痛经、闭经、补血、活血、通络、血虚萎黄、麻木瘫痪、风湿痹痛；
丹参，性味：苦、微温，具有活血祛瘀、安神宁心、排脓、止痛之功效，用于治疗心绞痛、月经不调、痛经、经闭、血崩带下、症瘕、积聚、瘀血腹痛、骨节疼痛、惊悸不眠、恶疮肿毒；
当归，性味：性温、味甘辛, 具有补血和血、调经止痛、润燥滑肠之功效，用于治疗血虚、面色萎黄、眩晕心悸、血虚、或兼有瘀滞的月经不调、经闭、痛经、虚寒性腹痛、冠心病心绞痛、风湿痹痛、跌打损伤等症；
桃仁，性味：苦甘、平，具有破血行瘀、润燥滑肠之功效，用于治疗经闭、症瘕、热病蓄血、风痹、疟疾、跌打损伤、瘀血肿痛、血燥便秘等症；
赤芍，性味：苦、微寒，具有清热凉血、活血祛瘀之功效，用于治疗温毒发斑、吐血衄血、肠风下血、目赤肿痛、痈肿疮疡、闭经、痛经、崩带淋浊、瘀滞胁痛、疝瘕积聚、跌扑损伤；
灵芝，性味：甘、平，具有补气安神、止咳平喘之功效，用于治疗眩晕不眠、心悸气短、虚劳咳喘；
红花，性味：辛、温，具有活血能经、祛瘀止痛之功效，用于治疗经闭、痛经、产后瘀阻腹痛、胞痹心痛症瘕积聚、跌打损伤、关节疼痛、中风偏竣、斑疹等症；
降香，性味：辛、温，无毒，具有活血散瘀、止血定痛、降气、辟秽之功效，用于治疗胸胁疼痛、跌打损伤、创伤出血、以及寒疝疼痛或秽浊内阻之呕吐腹痛等症；
郁金，性味：辛苦、凉，具有行气解郁、凉血破瘀之功效，用于治疗胸腹胁肋诸痛、失心癫狂、热病神昏、吐血、衄血、尿血、血淋、妇女倒经、黄疸等症；
益母草，性味：味辛、苦、性微进，具有活血调经、利尿消肿、清热解毒之功效，用于治疗月经不调、经闭、胎漏难产、胞衣不上、产后血晕、瘀血腹痛、跌打损伤、小便不利、水肿、头号肿疮疡；
三七，性味：甘、微苦、温，具有散瘀止血、消肿定痛之功效，用于治疗咯血、吐血、衄血、便血、崩漏、外伤出血、胸腹剌痛、跌扑肿痛等症；
川芎，性味：辛、温，具有活血祛瘀、行气开郁、祛风止痛之功效，用于治疗月经不调、经闭痛经、产后瘀滞腥痛、症瘕肿块、胸胁疼痛、头痛眩晕、风寒湿痹、跌打损伤、痈疽疮疡；
陈皮，性味：苦、辛、温，具有理气健脾、调中、燥湿、化痰之功效，用于治疗脾胃气滞之脘腹胀满或疼痛、消化不良、湿浊阻中之胸闷腹胀、纳呆便溏、痰湿壅肺之咳嗽气喘、食少吐泻、咳嗽痰多等症；
木香，性味：辛苦、温，具有行气止痛、温中和胃之功效，用于治疗中寒气滞、胸腹胀痛、呕吐、泄泻、下痢里急后重、寒疝；
石菖蒲，性味：辛、微温，具有开窍、豁痰、理气、活血、散风、去湿之功效，用于治疗癫痫、痰厥、，热病神昏、健忘、气闭耳聋、心胸烦闷、胃痛、腹痛、风寒湿痹、痈疽肿毒、跌打损伤；
枸杞子，性味：味甘、性平，具有养肝、滋肾、润肺之功效，用于治疗肝肾亏虚、头晕目眩、目视一清、腰膝酸软、阳痿贵精、虚劳咳嗽、消渴引饮等症；
酒黄精，性味：甘、平，具有养阴润肺、补脾益气、滋肾填精之功效，具有阴虚劳嗽、肺燥咳嗽、脾虚乏力、食少口干、消渴、肾亏腰膝酸软、阳痿遗精、耳鸣目暗、须发早白、体虚赢瘦、风癞癣疾等症；
人参，性味：甘微苦、温，具有大补元气、固脱生津、安神之功效，用于治疗劳伤虚损、食少、倦怠、反胃吐食、大便滑泄、虚咳喘促、自汗暴脱、惊悸、健忘、眩晕头痛、阳痿、尿频、消渴、妇女崩漏、小儿慢惊、及久虚不复、一切气血津液不足；
麦冬，性味：甘、微苦、微寒，具有养阴生津、润肺清心之功效，用于治疗肺燥干咳、虚痨咳嗽、津伤口渴、心烦失眠、内热消渴、肠燥便秘、咽白喉等症；
泽泻（盐制），性味：甘、寒，具有利水、渗湿、泄热之功效，用于治疗小便不利、水肿胀满、呕吐、泻痢、痰饮、脚气、淋病、尿血等症；
冰片，性味：辛、苦、微寒，具有开窍醒神、清热止痛之功效，用于治疗热病神昏、痉厥、中风痰厥、气郁暴厥、中恶昏迷、目赤、口疮、咽喉肿痛、耳道流脓等症。
本发明药物是基于中医治疗冠心病心绞痛气滞血瘀证的辨病与辨证相结合的原则，从药理作用及作用机制认为：就冠心病心绞痛气滞血瘀证，本发明所提供的药物中的各原料中药药效共奏，对上述疾病有很好的治疗效果。
具体实施方式
本发明就是针对上述冠心病心绞痛气滞血瘀证的治疗而提出的一种中药配方，采用该配方制备的药物药效好，见效快，是一个标本兼治的中药组方，特别适合临床使用。下面结合本发明的具体实施方式作进一步详细的描述：
实施例1：
一种治疗冠心病心绞痛气滞血瘀证的中药组合物，其特征在于，所述中药组合物的各个组分及其质量份比如下所示：
鸡血藤200g、丹参120g、当归120g、桃仁120g、赤芍90g、灵芝90g、红花90g、降香120g、郁金120g、益母草120g、三七80g、川芎80g、陈皮80g、木香80g、石菖蒲80g、枸杞子150g、酒黄精120g、人参120g、麦冬150g、泽泻（盐制）150g、冰片3g。
实施例2：
一种治疗冠心病心绞痛气滞血瘀证的中药组合物，其特征在于，所述中药组合物的各个组分及其质量份比如下所示：
鸡血藤230g、丹参140g、当归140g、桃仁140g、赤芍105g、灵芝105g、红花105g、降香140g、郁金140g、益母草140g、三七90g、川芎90g、陈皮90g、木香90g、石菖蒲90g、枸杞子170g、酒黄精140g、人参140g、麦冬170g、泽泻（盐制）170g、冰片2～3.2g。
实施例3：
一种治疗冠心病心绞痛气滞血瘀证的中药组合物，其特征在于，所述中药组合物的各个组分及其质量份比如下所示：
鸡血藤260g、丹参160g、当归160g、桃仁160g、赤芍120g、灵芝120g、红花120g、降香160g、郁金160g、益母草160g、三七100g、川芎100g、陈皮100g、木香100g、石菖蒲100g、枸杞子200g、酒黄精160g、人参160g、麦冬200g、泽泻（盐制）200g、冰片3.5g。
典型病例
经临床诊断治疗冠心病心绞痛气滞血瘀证患者共615例，年龄为50岁以上的310例，只有305例为50岁以下。615例患者中显效的277例，有效的308例，无效的30例，总有效率达95%。

Claims (3)

1.一种治疗冠心病心绞痛气滞血瘀证的中药组合物，其特征在于，所述中药组合物的各个组分及其质量份比如下所示：
鸡血藤150～260g、丹参80～160g、当归80～160g、桃仁80～160g、赤芍60～120g、灵芝60～120g、红花50～120g、降香90～160g、郁金80～160g、益母草100～160g、三七30～100g、川芎30～100g、陈皮30～100g、木香30～100g、石菖蒲50～100g、枸杞子100～200g、酒黄精100～160g、人参30～160g、麦冬100～200g、泽泻（盐制）100～200g、冰片1.8～3.5g。
2.根据权利要求1所述的治疗冠心病心绞痛气滞血瘀证的中药组合物，其特征在于，所述中药组合物的各个组分及其质量份比如下所示：
鸡血藤170～230g、丹参90～140g、当归90～140g、桃仁90～140g、赤芍70～105g、灵芝70～105g、红花60～105g、降香100～140g、郁金90～140g、益母草115～140g、三七40～90g、川芎40～90g、陈皮40～90g、木香40～90g、石菖蒲60～90g、枸杞子115～170g、酒黄精115～140g、人参40～140g、麦冬115～170g、泽泻（盐制）115～170g、冰片2～3.2g。
3.根据权利要求1至2所述的治疗冠心病心绞痛气滞血瘀证的中药组合物，其特征在于，所述中药组合物的各个组分及其质量份比如下所示：
鸡血藤200g、丹参120g、当归120g、桃仁120g、赤芍90g、灵芝90g、红花90g、降香120g、郁金120g、益母草120g、三七80g、川芎80g、陈皮80g、木香80g、石菖蒲80g、枸杞子150g、酒黄精120g、人参120g、麦冬150g、泽泻（盐制）150g、冰片3g。
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CN107375855A (zh) * 2017-09-05 2017-11-24 王文春 一种治疗冠心病心绞痛的药物及其制备方法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107375855A (zh) * 2017-09-05 2017-11-24 王文春 一种治疗冠心病心绞痛的药物及其制备方法

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