CN105477614A - 一种治疗肥胖的药物及其制备方法 - Google Patents

一种治疗肥胖的药物及其制备方法 Download PDF

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CN105477614A
CN105477614A CN201511002055.7A CN201511002055A CN105477614A CN 105477614 A CN105477614 A CN 105477614A CN 201511002055 A CN201511002055 A CN 201511002055A CN 105477614 A CN105477614 A CN 105477614A
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余勇
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Abstract

本发明公开了一种治疗肥胖的药物及其制备方法,其主要是由白术,荷叶,茯苓,泽泻,防己,陈皮,决明子,山楂,薏苡仁,赤小豆,大黄,枳实,天南星,枇杷叶等按一定重量配比制备而成,本发明药物具有利水除湿,消肿泻下的功能,用于治疗肥胖见效快,疗效好,无副作用。

Description

一种治疗肥胖的药物及其制备方法
技术领域
本发明涉及一种治疗肥胖的药物及其制备方法,属中药领域。
背景技术
肥胖症是一种由多种因素引起的慢性代谢性疾病,以体内脂肪细胞的体积和细胞数增加致体脂占体重的百分比异常增高并在某些局部过多沉积脂肪为特点。单纯性肥胖患者全身脂肪分布比较均匀,没有内分泌紊乱现象,也无代谢障碍性疾病,其家族往往有肥胖病史。由于西药无法有效快速治疗肥胖,因此人们对有效治疗肥胖的中药药物存在极大的需求,至今为止,还没有发现关于本发明的有关报道。
发明内容
本发明人依据中医理论的研究和临床试验的反复验证,终于找到了有效治疗肥胖的药物,从而完成了本发明。
本发明的目的就是提供一种更有效的治疗肥胖的中药组合药物。
本发明的另一目的就是提供了该中药组合药物的制备方法。
本发明药物是选择白术,荷叶,茯苓,泽泻,防己,陈皮,决明子,山楂,薏苡仁,赤小豆,大黄,枳实,天南星,枇杷叶,半夏,甘草,竹茹,黄芩,川芎,枳壳,大腹皮,冬瓜皮,香附,茵陈蒿,何首乌,夏枯草,莱菔子,黄芪,党参,生姜,大枣,白芷,黄柏,牛膝,车前草,虎杖,地骨皮,麻黄原料药进行组合制备的,将这些药物组合使得各药物功效产生协同作用,从而能够有效治疗肥胖。其中,选用白术是因为其性味苦甘,温,入脾、胃经,有补脾,益胃,燥湿,和中的功能,治脾胃气弱,不思饮食,倦怠少气,虚胀,泄泻,痰饮,水肿,黄疸,湿痹,小便不利,头晕,自汗,胎气不安。选用荷叶是因为其性味苦涩,平,入心、肝、脾经,有清暑利湿,升发清阳,止血的功能,治暑湿泄泻、眩晕,水气浮肿,雷头风,吐血,衄血,崩漏,便血,产后血晕。选用茯苓是因为其性味甘淡,平,入心、脾、肺经,有渗湿利水,益脾和胃,宁心安神的功能,治小便不利,水肿胀满,痰饮咳逆,呕哕,泄泻,遗精,淋浊,惊悸,健忘。选用泽泻是因为其性味甘,寒,入膀胱经,有利水,渗湿,泄热的功能,治小便不利,水肿肛满,呕吐,泻痢,痰饮,脚气,淋病,尿血。选用防己是因为其性味苦,寒,入膀膛、脾、肾经,有行水,泻下焦湿热的功能,治水肿臌胀,湿热脚气,手足挛痛,癣疥疮肿。选用陈皮是因为其性味苦、辛,温,归肺、脾经,有理气健脾,燥湿化痰的功能,治胸脘胀满,食少吐泻,咳嗽痰多。选用决明子是因为其性味苦甘,凉,入肝、肾经,有清肝,明目,利水,通便的功能,治风热赤眼,青盲,雀目,高血压,肝炎,肝硬化腹化,习惯性便秘。选用山楂是因为其性味酸甘,微温,入脾、胃、肝经,有消食积,散瘀血,驱绦虫的功能,治肉积,癥瘕,痰饮,痞满,吞酸,泻痢,肠风,腰痛,疝气,产后儿枕痛,恶露不尽,小儿乳食停滞。选用薏苡仁是因为其性味甘淡,凉,入脾、肺、肾经,有健脾,补肺,清热,利湿的功能,治泄泻,湿痹,筋脉拘挛,屈伸不利,水肿,脚气,肺痿,肺痈,肠痈,淋浊,白带。选用赤小豆是因为其性味甘酸,平,入心、小肠经,有利水除湿,和血排脓,消肿解毒的功能,治水肿,脚气,黄疸,泻痢,便血,痈肿。选用大黄是因为其性味苦、寒,入胃、大肠、肝径,有泻热毒,破积滞,行瘀血的功能,治实热便秘,谵语发狂,食积痞满,痢疾初起,里急后重,瘀停经闭,癥瘕积聚,时行热疫,暴眼赤痛,吐血,衄血,阳黄,水肿,淋浊,溲赤,痈疡肿毒,疔疮,汤火伤。选用枳实是因为其性味苦,寒,入脾、胃经,有破气,散痞,泻痰,消积的功能,治胸腹胀痛,胸痹,痞痛,痰癖,水肿,食积,便秘,胃下垂,子宫下垂,脱肛。选用天南星是因为其性味苦辛,温,有毒,入肺、肝、脾经,有燥湿化痰,祛风定惊,消肿散结的功能,治中风痰壅,口眼斜,半身不遂,癫癎,惊风,破伤风,风痰眩晕,喉痹,瘰疬,痈肿,跌扑折伤,蛇虫咬伤。选用枇杷叶是因为其性味苦,凉,归肺、胃经,有清肺和胃,降气化痰,治肺热痰嗽,咳血,衄血,胃热呕哕。选用半夏是因为其性味辛,温,有毒,入脾、胃经,有燥湿化痰,降逆止呕,消痞散结的功能,治湿痰冷饮,呕吐,反胃,咳喘痰多,胸膈胀满,痰厥头痛,头晕不眠,外消痈肿。选用甘草是因为其性味甘平,入脾、胃、肺经,有和中缓急,润肺,解毒,调和诸药的功能,炙用治脾胃虚弱,食少,腹痛便溏,劳倦发热,肺痿咳嗽,心悸,惊痈,生用治咽喉肿痛,消化性溃疡,痈疽疮疡,解药毒及食物中毒。选用竹茹是因为其性味甘,凉,入胃、胆经,有清热,凉血,化痰,止吐的功能,治烦热呕吐、呃逆,痰热咳喘,吐血,衄血,崩漏,恶阻,胎动,惊癎。选用黄芩是因为其性味苦寒,入心肺、胆、大肠经,有泻实火,除湿热,止血安胎的功能,治壮热烦渴,肺热咳嗽。选用川芎是因为其性味辛,温,入肝、胆经,有行气开郁,祛风燥湿,活血止痛的功能,治风冷头痛旋晕,胁痛腹疼,寒痹筋挛,经闭,难产,产后瘀阻块痛,痈疽疮疡。选用枳壳是因为其性味苦辛,凉,入肺、脾、大肠经,有破气,行痰,消积的功能,治胸膈痰滞,胸痞,胁胀,食积,噫气,呕逆,下痢后重,脱肛,子宫脱垂。选用大腹皮是因为其性味辛,微温,入脾、胃、大小肠经,有下气宽中,行水的功能,治脘腹痞胀,脚气,水肿。选用冬瓜皮是因为其性味甘,凉,入脾、肺二经,有利水消种的功能,治水肿,腹泻,痈肿。选用香附是因为其性味辛微苦干,平,入肝、三焦经,有理气解郁,止痛调经的功能,治肝胃不和,气郁不舒,胸腹胁肋胀痛,痰饮痞满,月经不调,崩漏带下。选用茵陈蒿是因为其性味苦辛,凉,入肝、脾、膀胱经,有清热利湿的功能,治湿热黄疸,小便不利,风痒疮疥。选用何首乌是因为其性味苦甘涩,微温,入肝、肾经,有补肝,益肾,养血,祛风的功能,治肝肾阴亏,发须早白,血虚头晕,腰膝软弱,筋骨酸痛,遗精,崩带,久疟,久痢,慢性肝炎,痈肿,瘰疬,肠风,痔疾。选用夏枯草是因为其性味苦辛,寒,入肝、胆经,有清肝,散结的功能,治瘰疬,瘿瘤,乳痈,乳癌,目珠夜痛,羞明流泪,头目眩晕,口眼歪斜,筋骨疼痛,肺结核,急性黄疸型传染性肝炎,血崩,带下。选用莱菔子是因为其性味辛甘,平,入肺、胃经,有下气定喘,消食化痰的功能,治咳嗽痰喘,食积气滞,胸闷腹胀,下痢后重。选用黄芪是因为其性味甘,微温,入肺、脾经,生用有益卫固表,利水消肿,托毒,生肌的功能,治自汗,盗汗,血痹,浮肿,痈疽不溃或溃久敛;炙用有补中益的功能,治内伤劳倦,脾虚泄泻,脱肛,气虚血脱,崩带及一切气衰血虚之症。选用党参是因为其性味甘,平,入手、足太阴经气分,有补中益气,生津的功能,治脾胃虚弱,气血两亏,体倦无力,食少,口渴,久泻,脱肛。选用生姜是因为其性味辛,温,入肺、胃、脾经,有发表,散寒,止呕,开痰的功能,治感冒风寒,呕吐,痰饮,喘咳,胀满,泄泻,解半夏、天南星及鱼蟹、鸟兽肉毒。选用大枣是因为其性味甘,温,入脾、胃经,有补脾和胃,益气生津,调营卫,解药毒的功能,治胃虚食少,脾弱便溏,气血津液不足,营卫不和,心悸怔忡,妇人脏躁。选用白芷是因为其性味辛,温,入肺、脾、胃经,有祛风,燥湿,消肿,止痛的功能,治头痛,眉棱骨痛,齿痛,鼻渊,寒湿腹痛,肠风痔漏,赤白带下,痈疽疮疡,皮肤燥痒,疥癣。选用黄柏是因为其性味苦,寒,入肾、膀胱经,有清热,燥湿,泻火,解毒的功能,治热痢,泄泻,消渴,黄疸,痿躄,梦遗,淋浊,痔疮,便血,赤白带下,骨蒸劳热,目赤肿痛,口舌生疮,疮疡肿毒。选用牛膝是因为其性味甘苦酸,平,入肝、肾经,生用散瘀血,消痈肿的功能,治淋病,尿血,经闭,癥瘕,难产,胞衣不下,产后瘀血腹痛,喉痹,痈肿,跌打损伤,熟用补肝肾,强筋骨,治腰膝骨痛,四肢拘挛,痿痹。选用车前草是因为其性味甘,寒,入肝、脾二经,有利水,清热,明目,祛痰的功能,治小便不通,淋浊,带下,尿血,黄疸,水肿,热痢,泄泻,鼻衄,目赤肿痛,喉痹乳蛾,咳嗽,皮肤溃疡。选用虎杖是因为其性味苦,平,有祛风,利湿,破瘀,通经的功能,治风湿筋骨疼痛,湿热黄疸,淋浊带下,妇女经闭,产后恶露不下,癥瘕积聚,痔漏下血,跌扑损伤,烫伤,恶疮癣疾。选用地骨皮是因为其性味甘,寒,入肺、肝、肾经,有清热,凉血的功能,治虚劳潮热盗汗,肺热咳喘,吐血,衄血,血淋,消渴,高血压,痈肿,恶疮。选用麻黄是因为其性味辛苦,温,入肺、膀胱经,有发汗,平喘,利水的功能,治伤寒表实,发热恶寒无汗、头痛鼻塞、骨节疼痛,咳嗽气喘,风水浮肿,小便不利,风邪顽痹,皮肤不仁,风疹瘙痒。
具体实施方式
本发明组分的药物用量也是发明人经过大量摸索总结得出的,各组分的用量在下述重量范围内都具有较好的疗效:
白术10-14克,荷叶8-12克,茯苓13-17克,泽泻14-16克,防己4-6克,陈皮8-12克,决明子8-12克,山楂8-10克,薏苡仁25-35克,赤小豆20-30克,大黄8-12克,枳实8-12克,天南星9-11克,枇杷叶8-12克,半夏6-10克,甘草10-15克,竹茹10-15克,黄芩10-15克,川芎10-15克,枳壳10-15克,大腹皮10-15克,冬瓜皮10-15克,香附10-15克,茵陈蒿15-25克,何首乌8-12克,夏枯草8-11克,莱菔子8-12克,黄芪6-10克,党参6-10克,生姜6-12克,大枣4-6克,白芷6-10克,黄柏6-10克,牛膝6-10克,车前草6-10克,虎杖15-25克,地骨皮10-15克,麻黄6-10克。
优选为:
白术12克,荷叶12克,茯苓15克,泽泻15克,防己5克,陈皮10克,决明子10克,山楂10克,薏苡仁30克,赤小豆30克,大黄10克,枳实10克,天南星10克,枇杷叶10克,半夏8克,甘草12克,竹茹12克,黄芩12克,川芎12克,枳壳12克,大腹皮12克,冬瓜皮12克,香附12克,茵陈蒿20克,何首乌10克,夏枯草10克,莱菔子10克,黄芪8克,党参8克,生姜10克,大枣6克,白芷6克,黄柏7克,牛膝6克,车前草6克,虎杖20克,地骨皮12克,麻黄10克。
本发明药物的制备方法如下
一、备料
1、白术:拣净杂质,用水浸泡,泡后捞出,润透,切片,晒干;
2、荷叶:以水洗净,剪去蒂与边缘,切丝,晒干;
3、茯苓:用水浸泡,洗净,捞出,闷透后,切片,晒干;
4、泽泻:拣去杂质,大小分档,用水浸泡至八成透,捞出,晒凉,闷润至内外湿度均匀,切片,晒干;
5、防己:原药用水洗净,捞出润透,切片,晒干;
6、陈皮:取原药材,除去杂质及变黑的果皮,抢水洗净,润软,切丝,晒干或低温干燥,筛去灰屑;
7、决明子:取净决明子,置锅内炒至微有香气,取出,放凉;
8、山楂:拣净杂质,筛去核;
9、薏苡仁:取原药材,除去残留皮壳、杂质;
10、赤小豆:取原药材,除去杂质,用时捣碎;
11、大黄:拣净杂质,大小分档,焖润至内外湿度均匀,切片或切成小块、晒干;
12、枳实:拣净杂质,用水浸泡至八成透,捞出,润至内无硬心,切片,晾干;
13、天南星:拣去杂质,洗净灰屑,晒干;
14、枇杷叶:刷去绒毛,用水洗净,稍润,切丝,晒干;
15、半夏:拣去杂质,筛去灰屑;
16、甘草:拣去杂质,洗净,用水浸泡至八成透时,捞出,润透,切片,晾干;
17、竹茹:除去硬竹签、杂质,抖掉灰屑,揉成小团或切段;
18、黄芩:拣去杂质,除去残茎,用凉水浸润或置开水中稍浸捞出,切片,晒干;
19、川芎:拣去杂质,分开大、小个,用水浸泡,晒晾,闷润后切片,干燥;
20、枳壳:除去瓤、核,冼净,稍浸,捞出,润软,以手能捏对折为止,切片,晾干;
21、大腹皮:拣净杂质,碾轧使软,敲打,筛去泥屑;
22、冬瓜皮:取原药材,除去杂质及霉烂变质者,抢水洗净,切块或丝,干燥,筛去碎屑;
23、香附:拣去杂质,碾成碎粒,簸去细毛及细末;
24、茵陈蒿:过筛,拣去杂质,除去残根,碾碎,再过筛去净泥屑;
25、何首乌:拣去杂质,洗净,用水泡至八成透,捞出,润至内外湿度均匀,切片或切成方块,晒干;
26、夏枯草:取原药材,除去枝梗、叶片及杂质,筛去灰屑;
27、莱菔子:簸去杂质,漂净泥土,捞出,晒干,用时捣碎;
28、黄芪:拣净杂质,除去残留的根头和空心较大的根,用水浸泡,捞出,润透后及时切片,晒干;
29、党参:洗净泥沙后润透去芦,切片或切段,晒干;
30、生姜:拣去杂质,洗净泥土,用时切片;
31、大枣:拣净杂质,晒干;
32、白芷:拣净杂质,用水洗净,浸泡,捞出润透,略晒至外皮无滑腻感时,再闷润后,切片干燥;
33、黄柏:拣去杂质,用水洗净,捞出,润透,切片或切丝,晒干;
34、牛膝:拣去杂质,洗净,润软,去芦,切段,晒干;
35、车前草:去尽泥土,晒干;
36、虎杖:采得后,细锉,晒干;
37、地骨皮:拣去杂质及木心,略洗,切段,晒干;
38、麻黄:拣去杂质,去尽木质茎及残根,用水洗净,微润后切段,干燥;
二、制备
1、将所述重量的白术,荷叶,茯苓,泽泻,防己,陈皮,决明子,山楂,薏苡仁,赤小豆,大黄,枳实,天南星,枇杷叶,半夏,甘草,竹茹,黄芩,川芎,枳壳,大腹皮,冬瓜皮,香附,茵陈蒿,何首乌,夏枯草,莱菔子,黄芪,党参,生姜,大枣,白芷,黄柏,牛膝,车前草,虎杖,地骨皮,麻黄放入煎药容器内,第一次加水8倍量,浸泡60分钟后,武火煎煮沸腾,再用文火煎煮30分钟,过滤得第一次煎煮液,将第一次煎煮液倒入容器内;
2、将过滤的药渣加水6倍量,武火煮沸,再用文火煎煮20分钟过滤,将第二次煎煮液倒入容器内;
3、将两次煎煮液混合搅拌均匀,即得混合药液,分成4剂服用。
组方中茯苓有渗湿利水,益脾和胃功能为君药;泽泻利水,渗湿,泄热,防己行水,泻下,祛湿二者为臣药,三味药共同发挥利水渗湿,泻下和中的作用,治疗肥胖效力全面,且以利水渗湿为主,可治本;赤小豆利水除湿,和血排脓,消肿解毒为佐药;甘草有和中缓急,润肺,解毒,调和诸药的功能与下余诸药是治标。
本发明药物具有利水除湿,消肿泻下的功能,用于治疗肥胖,疗程短、见效快、治愈后不复发、无毒副作用。
具体实施方式:
以下通过试验例来进一步阐述本发明所述药物的有益效果,这些试验例包括本发明药物的动物毒性试验报告和临床疗效观察资料。
[试验例1]本发明药物的动物毒性试验报告:
取家兔30只,雌雄兼用,体重2.0—2.5kg,分两组,每组15只,其中一组为超剂量试验组,另一组为正常量试验组。服用药液超常量组为20ml/kg,正常量为10ml/kg,给药方式为灌胃法给药,每天两次,连服7天,每天观察给药反应,结果表明二组家兔活动、饮食正常,药物无不良毒副作用。
[试验例2]本发明药物的临床疗效观察
1、一般资料
收治肥胖门诊患者共28例。
2、诊断标准
临床上,这类病人全身脂肪分布比较均匀,没有内分泌紊乱现象,也无代谢障碍性疾病,其家族往往有肥胖病史。目前临床用体重指数(BMI)来评价:<18.5kg·m-2者为体重过低,18.5~23.9kg·m-2为正常范围,≥24kg·m-2为超重;≥28kg·m-2为肥胖。但应该注意有些BMI增高的患者不是脂肪增多,而是肌肉或者其他组织增多。
3、治疗方法
选用上述药剂,给患者服用,一日2次,每次服用1剂,每天早、晚各服1次,15天为一个疗程,连续服用3个疗程。
4、疗效评定标准
显效:肥胖症状消失,痊愈,体质恢复正常;
好转:肥胖症状明显好转,水肿症状已消除,体质逐步恢复;
无效:达不到好转标准者。
5、治疗结果(见下表)
在上述治疗中,用本发明药物治疗肥胖患者28例,结果显效22例,显效率为78.57%,好转5例,好转率为17.86%,无效1例,总有效率为96.43%。

Claims (3)

1.一种治疗肥胖的药物,其特征在于:它是由下列用量范围内的原料药制成:
白术10-14克,荷叶8-12克,茯苓13-17克,泽泻14-16克,防己4-6克,陈皮8-12克,决明子8-12克,山楂8-10克,薏苡仁25-35克,赤小豆20-30克,大黄8-12克,枳实8-12克,天南星9-11克,枇杷叶8-12克,半夏6-10克,甘草10-15克,竹茹10-15克,黄芩10-15克,川芎10-15克,枳壳10-15克,大腹皮10-15克,冬瓜皮10-15克,香附10-15克,茵陈蒿15-25克,何首乌8-12克,夏枯草8-11克,莱菔子8-12克,黄芪6-10克,党参6-10克,生姜6-12克,大枣4-6克,白芷6-10克,黄柏6-10克,牛膝6-10克,车前草6-10克,虎杖15-25克,地骨皮10-15克,麻黄6-10克。
2.根据权利要求1所述的药物,其中各原料药的用量为:
白术12克,荷叶12克,茯苓15克,泽泻15克,防己5克,陈皮10克,决明子10克,山楂10克,薏苡仁30克,赤小豆30克,大黄10克,枳实10克,天南星10克,枇杷叶10克,半夏8克,甘草12克,竹茹12克,黄芩12克,川芎12克,枳壳12克,大腹皮12克,冬瓜皮12克,香附12克,茵陈蒿20克,何首乌10克,夏枯草10克,莱菔子10克,黄芪8克,党参8克,生姜10克,大枣6克,白芷6克,黄柏7克,牛膝6克,车前草6克,虎杖20克,地骨皮12克,麻黄10克。
3.根据权利要求1或2所述药物的制备方法,它包括下列步骤:
(一)备料
(1)白术:拣净杂质,用水浸泡,泡后捞出,润透,切片,晒干;
(2)荷叶:以水洗净,剪去蒂与边缘,切丝,晒干;
(3)茯苓:用水浸泡,洗净,捞出,闷透后,切片,晒干;
(4)泽泻:拣去杂质,大小分档,用水浸泡至八成透,捞出,晒凉,闷润至内外湿度均匀,切片,晒干;
(5)防己:原药用水洗净,捞出润透,切片,晒干;
(6)陈皮:取原药材,除去杂质及变黑的果皮,抢水洗净,润软,切丝,晒干或低温干燥,筛去灰屑;
(7)决明子:取净决明子,置锅内炒至微有香气,取出,放凉;
(8)山楂:拣净杂质,筛去核;
(9)薏苡仁:取原药材,除去残留皮壳、杂质;
(10)赤小豆:取原药材,除去杂质,用时捣碎;
(11)大黄:拣净杂质,大小分档,焖润至内外湿度均匀,切片或切成小块、晒干;
(12)枳实:拣净杂质,用水浸泡至八成透,捞出,润至内无硬心,切片,晾干;
(13)天南星:拣去杂质,洗净灰屑,晒干;
(14)枇杷叶:刷去绒毛,用水洗净,稍润,切丝,晒干;
(15)半夏:拣去杂质,筛去灰屑;
(16)甘草:拣去杂质,洗净,用水浸泡至八成透时,捞出,润透,切片,晾干;
(17)竹茹:除去硬竹签、杂质,抖掉灰屑,揉成小团或切段;
(18)黄芩:拣去杂质,除去残茎,用凉水浸润或置开水中稍浸捞出,切片,晒干;
(19)川芎:拣去杂质,分开大、小个,用水浸泡,晒晾,闷润后切片,干燥;
(20)枳壳:除去瓤、核,冼净,稍浸,捞出,润软,以手能捏对折为止,切片,晾干;
(21)大腹皮:拣净杂质,碾轧使软,敲打,筛去泥屑;
(22)冬瓜皮:取原药材,除去杂质及霉烂变质者,抢水洗净,切块或丝,干燥,筛去碎屑;
(23)香附:拣去杂质,碾成碎粒,簸去细毛及细末;
(24)茵陈蒿:过筛,拣去杂质,除去残根,碾碎,再过筛去净泥屑;
(25)何首乌:拣去杂质,洗净,用水泡至八成透,捞出,润至内外湿度均匀,切片或切成方块,晒干;
(26)夏枯草:取原药材,除去枝梗、叶片及杂质,筛去灰屑;
(27)莱菔子:簸去杂质,漂净泥土,捞出,晒干,用时捣碎;
(28)黄芪:拣净杂质,除去残留的根头和空心较大的根,用水浸泡,捞出,润透后及时切片,晒干;
(29)党参:洗净泥沙后润透去芦,切片或切段,晒干;
(30)生姜:拣去杂质,洗净泥土,用时切片;
(31)大枣:拣净杂质,晒干;
(32)白芷:拣净杂质,用水洗净,浸泡,捞出润透,略晒至外皮无滑腻感时,再闷润后,切片干燥;
(33)黄柏:拣去杂质,用水洗净,捞出,润透,切片或切丝,晒干;
(34)牛膝:拣去杂质,洗净,润软,去芦,切段,晒干;
(35)车前草:去尽泥土,晒干;
(36)虎杖:采得后,细锉,晒干;
(37)地骨皮:拣去杂质及木心,略洗,切段,晒干;
(38)麻黄:拣去杂质,去尽木质茎及残根,用水洗净,微润后切段,干燥;
(二)制备
1、将所述重量的白术,荷叶,茯苓,泽泻,防己,陈皮,决明子,山楂,薏苡仁,赤小豆,大黄,枳实,天南星,枇杷叶,半夏,甘草,竹茹,黄芩,川芎,枳壳,大腹皮,冬瓜皮,香附,茵陈蒿,何首乌,夏枯草,莱菔子,黄芪,党参,生姜,大枣,白芷,黄柏,牛膝,车前草,虎杖,地骨皮,麻黄放入煎药容器内,第一次加水8倍量,浸泡60分钟后,武火煎煮沸腾,再用文火煎煮30分钟,过滤得第一次煎煮液,将第一次煎煮液倒入容器内;
2、将过滤的药渣加水6倍量,武火煮沸,再用文火煎煮20分钟过滤,将第二次煎煮液倒入容器内;
3、将两次煎煮液混合搅拌均匀,即得混合煎煮液,分成4剂服用。
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CN106110092A (zh) * 2016-07-26 2016-11-16 河南中医学院 一种治疗单纯性肥胖的中药
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GB2608507A (en) * 2021-06-23 2023-01-04 Changsha Broad Ocean Bio Science And Technique Co Ltd Chinese herbal medicine composition for reducing weight and lowering blood sugar and its preparation

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