CN1062157C - Hepatitis B curing toxin-dissipating pill - Google Patents
Hepatitis B curing toxin-dissipating pill Download PDFInfo
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- CN1062157C CN1062157C CN96117808A CN96117808A CN1062157C CN 1062157 C CN1062157 C CN 1062157C CN 96117808 A CN96117808 A CN 96117808A CN 96117808 A CN96117808 A CN 96117808A CN 1062157 C CN1062157 C CN 1062157C
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Abstract
The present invention relates to a hepatitis B toxin-dissipating pill for treating qi stagnation, blood stasis, deficient vital qi leading to lingering of pathogen, dampness and heat in livers and gallbladders, yin deficiency, blood heat and kidney essence deficiency. The hepatitis B toxin-dissipating pill comprises 2 to 7 parts of bupleurum root, 2 to 7 parts of aurantii, 3 to 10 parts of white peony root, 2 to 4 parts of licorice, 3 to 10 parts of white atractylodes rhizome, 2 to 7 parts of curcuma root, 2 to 7 parts of nutagrass flatsedge rhizome, 2 to 7 parts of aucklandia root and 3 to 11 parts of adder tongue herb. The hepatitis B toxin-dissipating pill has conspicuous curative effects on killing hepatitis B viruses, converting surface antigen into negative, changing antibodies into positive, promoting liver cell regeneration, strengthening liver immunity and restoring liver function. The hepatitis B toxin-dissipating pill has low price; compared with western medicines for treating hepatitis B, the hepatitis B toxin-dissipating pill can save about 6 times of medical cost.
Description
The invention belongs to pure Chinese medicinal preparation, is the hepatitis B medicine pill of treatment qi depression to blood stasis, deficient vital QI leading to lingering of pathogen, dampness-heat in the liver and gallbladder, deficiency of YIN heat in blood, deficiency of the kidney hepatitis B.
Hepatitis B is the doctor trained in Western medicine name of disease, is that two double chemical examinations are its foundations due to the human infection hepatitis B virus.From traditional Chinese medical science viewpoint, this disease always belongs to deficiency in origin and excess in superficiality, and deficiency in origin is the deficiency of vital energy, the deficiency of YIN or yang deficiency, and standard card is based on " poison ", and the damp and hot stasis of blood of the traditional Chinese medical science all belongs to the category of poison.The sickness rate of hepatitis B is in rising trend in recent years in China, and people's health in serious threat.This course of disease is long, and repeatability is big, and atypical symptoms or no conscious sympton often find just in health check-up that weight person can develop into primary hepatocarcinoma.This disease does not still have definite Therapeutic Method at present.Through update search, check in two parts of patent documentations: 1. " treatment hepatitis B Chinese medicine " application number: 93105106.1, publication number: CN1078902A; 2. " hepatosis treating medicine powder " application number: 93107139.9, publication number: CN1096681A.Though they all are the treatment hepatopathys, its composition is different with the present invention, and curative effect is also not as the present invention.
Purpose of the present invention is exactly the deficiency that overcomes above treatment hepatitis B medicine, and provides a kind of scientific formulation strong, can cure, treat the hepatitis B medicine pill of various hepatopathys.
The objective of the invention is to realize by following composition:
Radix Bupleuri 2-7 Fructus Aurantii 2-7 Radix Paeoniae Alba 3-10 Radix Glycyrrhizae 2-4 Rhizoma Atractylodis Macrocephalae 3-10
Radix Curcumae 2-7 Rhizoma Cyperi 2-7 Radix Aucklandiae 2-7 Herba Ophioglossi 3-11
Its composition also can have: the parasitic 2-7 bark of eucommia of the red Qi 2-7 seed of Chinese dodder of benevolence 2-7 the root of straight ladybell 3-8 tortoiseshell 1-3 Radix Angelicae Sinensis 1-3 fruit of Chinese magnoliavine 1-3 golden cypress 2-7 root bark of Chinese wolf-berry 2-7 radix stellariae dichotomae 2-7 Eclipta prostrata 2-7 dried rhizome of rehmannia 2-9 donkey-hide gelatin 2-7 Chinese yam 3-7 fructus corni 2-9 2-7 Chinese cassia tree 1-3 deer horn glue 2-7 Radix Codonopsis 2-9 1-3 tuber of multiflower knotweed 2-9 before the radix paeoniae rubrathe 2-7 root bark of tree peony 2-7 giant knotweed 2-9 red sage root 2-7 Sculellaria barbata 2-9 HERBA HEDYOTIS DIFFUSAE 2-9 folium isatidis 2-6 pseudo-ginseng 1-3 dragon's blood 1-3 bubble ginseng 3-10 Radix Astragali 3-10 Poria cocos 2-7 branch 1-3 rheum officinale 1-3 cogongrass rhizome 2-7 Paris polyphylla 2-9 fruit of glossy privet 2-7 desmodium 2-7 almond 2-7 felwort 1-3 seed of jog's tears 3-12 bark of official magnolia 2-7 root of large-flowered skullcap 2-7 rhizoma alismatis 1-3 talcum 2-7 akebi 2-7
In conjunction with the laboratory objective indicator hepatitis B is divided into following five pattern of syndrome according to Chinese medical discrimination.
1) qi stagnation and blood stasis type
Right rib pain or discomfort, or enclosed mass under the right rib, there are petechia, stringy and hesitant pulse in distension and fullness in the abdomen, inappetence, pale tongue with white fur, the tip of the tongue limit.This type of patient mostly is chronic active hepatitis, the anti-HBe of the anti-HBS of serum HBSAg, the anti-HBC positive or the anti-HBe positive of serum HBSAg.
2) asthenic healthy qi with pathogen lingering type
No clinical manifestation or idol have dizzy refreshing tired, the tongue arteries and veins is normal.This type of patient mostly is the anti-HBC positive of hepatitis B virus carriers, the serum HBSAg positive or serum HBSAg.
3) liver gallbladder damp-heat type
Dry mouth with bitter taste, spiritlessness and too weak to speak, discomfort uncomfortable in chest, poor appetite are detested oil, the big dry stool of yellow urine, red tongue greasy fur, soft and rapid pulse.This type of patient mostly is the anti-HBC positive of hepatitis B chronic active phase serum HBSAg.
4) deficiency of YIN blood-heat type
Right rib dull pain or discomfort, xerostomia are not thought drink, the heating of brothers' heart, the few tongue thready and rapid pulse of red tongue.The anti-HBeAg positive of this type of patients serum HBSAg.
5) deficiency of the kidney type
Soreness of the waist and knees, the right rib discomfort in tired back, nocturia are not yellow, a little less than the spiritlessness and too weak to speak, pale tongue with white fur, deep-thready pulse.This type of patient's course of disease is long, the anti-HBC positive of the anti-HBe of serum HBSAg.
The present invention is based on the antidote Herba Ophioglossi.This medicine bitter but sweet flavor cold, heat-clearing and toxic substances removing, promoting blood circulation to remove blood stasis.Run through each method of treatment all the time with " removing toxic substances ", catch and remove this principal contradiction of hepatitis B virus, five pattern of syndrome are added and subtracted on the basis of basis side, demonstrated fully the elite of tcm treatment according to syndrome differentiation.
Good effect of the present invention is: use pure Chinese medicine, without Western medicine, except that the treatment hepatitis B, but also treating the liver splenomegaly, liver cirrhosis, fatty liver, hepatic cyst, hepatocarcinoma, and have and soothing the liverly hold up that spleen, promoting blood circulation and detoxication, soothing the liver dampness removing, QI invigorating are set upright, the yin nourishing easing the affected liver, support the effect of smart the kidney invigorating.
Criterion of therapeutical effect of the present invention
1) recovery from illness index: clinical symptom disappearance, the every index of two double chemical examinations is normal, and per check in March is once followed up a case by regular visits to no abnormal change in a year.
2) standard that is almost recovered: clinical symptom disappearance, the anti-HBC positive of the anti-HBS of two double chemical examinations, follow up a case by regular visits to and do not have change half a year.
3) improvement index: clinical cardinal symptom disappears. but the every index of two double chemical examinations does not have change.
4) invalid index: clinical symptoms and two double chemical examinations all do not change.
Therapeutic outcome of the present invention:
Among the 500 routine patients, 4 first quarter moons of average course of treatment, 50 examples of fully recovering account for 10%; 210 examples that are almost recovered account for 42%; 220 examples that take a turn for the better account for 44%; Invalid 20 examples account for 4%, total effective rate 96%.
Model case
1) Wang Jing, woman, 14 years old, first visit on June 21 in 95 year: county hospital chemically examine two double for the HBSAg positive, do not have any symptom, the tongue arteries and veins is normal, according to Chinese medical discrimination thinking viewpoint, belong to deficient vital QI leading to lingering of pathogen, control with soothing the liver dampness removing, Fuzheng Jiedu is advised the clothes embodiment of the invention 2 potions, do not have sense of discomfort January behind the medicine, for strengthening the soothing the liver spleen promoting blood circulation and detoxication reuse embodiment of the invention 1 potion of holding up.Chemically examine in the People's Hospital 95 on July 22, two double for complete negative, follow up a case by regular visits to so far recurrence.
2) Luo Yong, the man, 25 years old, examined 95 on April 28: right rib pain 2 years is surplus.It is surplus to suffer from hepatitis B 2 years, through intramuscular injection hepatitis B ribonucleic acid, transfer factor, and the delivery of energy mixture, the oral hepatitis B detoxicating capsule, MIEAOLING all curative effect is not good enough.95 on April 1, in Chengdu the 3rd the People's Hospital chemically examine two double for the anti-HBC positive of the anti-HBe of HBSAg.
Examine quarter: shape is thin, spiritlessness and too weak to speak, right rib pain, poor appetite yellow urine, red tongue with yellow fur, stringy and hesitant pulse.It is main that card belongs to qi depression to blood stasis, controls with the soothing the liver spleen of holding up, and promoting blood circulation and detoxication is earlier.Once issue the embodiment of the invention 1, embodiment 2, and embodiment 5 each potion advise him to obey in order, every day one ball, three times on the one after meal boiled water swallow, work as tea-drinking with Herba Artemisiae Annuae Herba Lysimachiae bubble boiled water at ordinary times, and advise his have a rest fewly to work the wine for giving off smoking maror more.After March patient through Chengdu the 3rd Crinis Carbonisatus hospital chemically examine two double for complete negative, follow up a case by regular visits to so far and recur.
3) Mu Depei, man 54 years old, examine 94 on November 5: refreshing tired general power, inappetence 1 year is surplus.The patient finds hepatitis B the year before, and symptom was not remarkable at that time, does not draw attention, and because of work relationship, tobacco and wine are excessive, feel lassitude gradually.
Examine quarter: spiritlessness and too weak to speak, emaciated physique, inappetence, insomnia and dreamful sleep, red tongue tongue the lung-pulse string.Have a medical check-up: the liver spleen do not lay one's hand on and, serum shows: the anti-HBC positive of the anti-HBe of HBSAg, card belongs to deficient vital QI leading to lingering of pathogen, liver-yang hyperactivity gram spleen is controlled with the soothing the liver detoxifcation of strengthening vital QI to eliminate pathogenic factors.Clothes present embodiment 2 potions are advised wine for giving off smoking, suitable work, having regular daily life.The further consultation in 5, of 94 on Decembers: symptom is clearly better behind the medicine, obeys embodiment 2 potions again, and instructions about how to take medicine are the same.Examine 95 on January 5, again: spirit is clearly better, and food is received and increased, and idol has right rib discomfort, and light red tongue tongue white edge has petechia, and the fat string is puckery, and card belongs to qi depression to blood stasis, controls with the soothing the liver spleen promoting blood circulation and detoxication of holding up.Give embodiment 1 potion again.Examine 95 on February 5, for the third time: symptom all disappears, and night's rest is good, and weight increase, food are received two just normal, and the tongue arteries and veins is normal, two double results of laboratory test: the anti-HBC positive of anti-HBS, follow up a case by regular visits to so far recurrence.
4) Liu Jianguo, the man, 37 years old, examined 95 on November 27: the right rib pain of patient 3 years.In two hospitals of Medical University Of Chongqing, Lu hospital saw as B ultrasonic once: hepatosplenomegaly, and alcoholic fatty liver, hydrocholecystis, this two double result of laboratory test is the anti-HBC positive of HBSAg HBeAg.
Examine quarter: right rib dull pain discomfort, refreshing tired general power, epigastrium can be laid one's hand on and enclosed mass, food receive still can, the white stringy and hesitant pulse of light red tongue tongue, card belongs to qi depression to blood stasis.Be in harmony with the soothing the liver spleen of holding up, promoting blood circulation and detoxication was advised the clothes present embodiment 1 five months, and clinical symptoms all disappears.In August, 95, two double chemical examination conclusions are the anti-HBC positive of anti-HBS.Again through ultrasound diagnosis: hepatosplenomegaly, hydrocholecystis, alcoholic fatty liver all disappears.
5) Chen Wenshu, the man, 43 years old, examined 96 on March 22: B ultrasonic shows: portal hypertension, liver cirrhosis, hepatomegaly, hydrocholecystis, the anti-HBC positive of serum HBSAg, HBeAg.
Examine quarter: abdominal distention, and oliguria, poor appetite, abdominal tympanites, three horizontal fingers under the right rib of liver, there is ecchymosis on the tongue limit, deep and hesitant pulse.Belong to qi depression to blood stasis, control with the soothing the liver spleen of holding up, promoting blood circulation and detoxication present embodiment 1.Period in a medicine, all are normal for the patient, in case drug withdrawal, ascites will appear in the patient.According to patient reflection, he is former when treat in Chongqing, and every month doctor's furuncle takes four or five thousand yuan, and present inventor locates to cure and only spent 200 yuans in every month, and curative effect is fine.
6) Luo Chaoyuan, man 33 years old, examine 96 on April 3: right rib pain is surplus May, and B ultrasonic shows: early stage fatty liver.
Examine quarter: right rib pain, food is received two just normal, red tongue tongue the lung-pulse string.Thin inquirys because of tobacco and wine are excessive for a long time.Card belongs to qi depression to blood stasis, controls with the soothing the liver spleen of holding up, promoting blood circulation and detoxication.Obeying the embodiment of the invention 1 right rib pain continuously February disappears.96 on July 9,, B ultrasonic showed: all are normal for hepato-biliary function.
The embodiment of the invention is as follows:
Embodiment 1 Radix Bupleuri 30g Fructus Aurantii 30g Radix Paeoniae Alba 80g Radix Glycyrrhizae 6g Rhizoma Atractylodis Macrocephalae 80g Radix Curcumae 30g Rhizoma Cyperi 30g Radix Aucklandiae 30g Herba Ophioglossi 100g Radix Paeoniae Rubra 30g Cortex Moutan 30g Rhizoma Polygoni Cuspidati 40g Radix Salviae Miltiorrhizae 30g Herba Scutellariae Barbatae 40g Herba Hedyotidis Diffusae 40g Folium Isatidis 30g Radix Notoginseng 15g Sanguis Draxonis 15g
Embodiment 2 Radix Bupleuri 30g Fructus Aurantii 30g Radix Paeoniae Alba 80g Radix Glycyrrhizae 6g Rhizoma Atractylodis Macrocephalae 80g Radix Curcumae 30g Rhizoma Cyperi 30g Radix Aucklandiae 30g Herba Ophioglossi 100g bubble ginseng 80g Radix Astragali 80g Poria 30g Radix Paeoniae Rubra 30g Fructus Gardeniae 20g Radix Et Rhizoma Rhei 18g Herba Hedyotidis Diffusae 30g Rhizoma Imperatae 30g Rhizoma Paridis 40g Fructus Ligustri Lucidi 30g Herba Lysimachiae 30g
Embodiment 3 Radix Bupleuri 30g Fructus Aurantii 30g Radix Paeoniae Alba 80g Radix Glycyrrhizae 6g Rhizoma Atractylodis Macrocephalae 80g Radix Curcumae 30g Rhizoma Cyperi 30g Radix Aucklandiae 30g Herba Ophioglossi 100g Semen Armeniacae Amarum 30g Radix Gentianae 20g Semen Coicis 100g Cortex Magnoliae Officinalis 30g Radix Scutellariae 30g Rhizoma Alismatis 20g Poria 30g Herba Lysimachiae 30g Talcum 30g Caulis Akebiae 30g Semen Plantaginis 30g Herba Hedyotidis Diffusae 40g
Embodiment 4 Radix Bupleuri 30g Fructus Aurantii 30g Radix Paeoniae Alba 80g Radix Glycyrrhizae 6g Rhizoma Atractylodis Macrocephalae 80g Radix Curcumae 30g Rhizoma Cyperi 30g Radix Aucklandiae 30g Herba Ophioglossi 100g Radix Paeoniae Rubra 20g Radix Salviae Miltiorrhizae 30g Radix Adenophorae (Radix Glehniae) 60g Carapax et Plastrum Testudinis 20g Radix Angelicae Sinensis 20g Fructus Schisandrae Chinensis 20g Cortex Phellodendri 30g Cortex Lycii 30g Radix Stellariae 30g Herba Ecliptae 30g Fructus Ligustri Lucidi 30g Radix Rehmanniae 40g Colla Corii Asini 30g
The parasitic 30g Cortex Eucommiae of embodiment 5 Radix Bupleuri 30g Fructus Aurantii 30g Radix Paeoniae Alba 80g Radix Glycyrrhizae 6g Rhizoma Atractylodis Macrocephalae 80g Radix Curcumae 30g Rhizoma Cyperi 30g Radix Aucklandiae 30g Herba Ophioglossi 100g Rhizoma Dioscoreae 60g Fructus Corni 40g Fructus Lycii 30g Semen Cuscutae 30g Cortex Cinnamomi 10g Colla cornus cervi 30g Radix Codonopsis 50g Radix Astragali 50g Radix Angelicae Sinensis 30g 20g Colla Plastri Testudinis 30g Radix Polygoni Multiflori 40g
Clothes the present invention should control principle by dialectical the executing of the strict grasp of doctor, looks its disease, uses its medicine, embodies the dialectical opinion of motherland's medical science and controls elite.It is fast to obey this invention alleviation clinical symptoms, and be a course of treatment March, changes once prescription (changing prescription according to the symptom decision) each ball (weighing 10g) in every month, and three times on the one boiled water advances clothes (taking medicine after meal).Can make HBSAg HBeAg sun turn out cloudy general one to two course of treatment, wherein also is no lack of full negative patient, but the asymptomatic person of the individual patient great three positive difficulty of turning out cloudy is also arranged.The present invention has no side effect through clinical verification.Period in a medicine is quitted smoking, wine, Rhizoma Zingiberis Recens, Pericarpium Zanthoxyli, Fructus Capsici.And advise few works of having a rest more, and the emotion that keeps pleasant is noted the restraining of sexual life, does not eat the fresh vegetables that pesticide effect duration does not cross, the anemia of pregnant woman prohibits clothes.
Claims (1)
1, a kind of medicine pill for the treatment of hepatitis B is characterized in that being made by the raw material of following weight portion,
Radix Bupleuri 2~7 Fructus Aurantiis 2~7 Radix Paeoniae Albas 3~10 Radix Glycyrrhizaes 2~4
The Rhizoma Atractylodis Macrocephalae 3~10 Radix Curcumaes 2~7 Rhizoma Cyperis 2~7 Radix Aucklandiae 2~7
Herba Ophioglossi 3~11 Radix Paeoniae Rubra 2~7 Cortex Moutans 2~7 Rhizoma Polygoni Cuspidati 2~9
Radix Salviae Miltiorrhizae 2~7 Herba Scutellariae Barbataes 2~9 Herba Hedyotidis Diffusae 2~9 Folium Isatidiss 2~6
Radix Notoginseng 1~3 Sanguis Draxonis 1~3.
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CN96117808A CN1062157C (en) | 1996-11-30 | 1996-11-30 | Hepatitis B curing toxin-dissipating pill |
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CN96117808A CN1062157C (en) | 1996-11-30 | 1996-11-30 | Hepatitis B curing toxin-dissipating pill |
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CN1160559A CN1160559A (en) | 1997-10-01 |
CN1062157C true CN1062157C (en) | 2001-02-21 |
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CN96117808A Expired - Fee Related CN1062157C (en) | 1996-11-30 | 1996-11-30 | Hepatitis B curing toxin-dissipating pill |
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CN1911400B (en) * | 2005-08-12 | 2010-04-14 | 孙祥度 | Compound poria cocos preparation, and its preparation method |
CN100377737C (en) * | 2005-10-26 | 2008-04-02 | 李永发 | Chinese traditional medicine composition for treating liver and kidney diseases and preparation method thereof |
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CN101828620A (en) * | 2010-05-11 | 2010-09-15 | 高玲 | Health protection tea for treating liver constraint and blockage |
CN102949658B (en) * | 2011-08-18 | 2014-01-08 | 张志通 | Drug formula for treating hepatitis |
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CN102772575B (en) * | 2012-08-17 | 2014-06-11 | 刘海霞 | Traditional Chinese medicine composition for treating chronic hepatitis B |
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CN103212034B (en) * | 2013-04-15 | 2014-07-23 | 刘海霞 | Chinese medicinal composition for treating chronic viral hepatitis |
CN103272187B (en) * | 2013-06-19 | 2014-10-08 | 黄禀檐 | Agent for curing liver cancer |
CN103623276B (en) * | 2013-12-13 | 2015-09-30 | 马振滨 | A kind of oral preparation of Chinese traditional medicinal for the treatment of hepatitis B |
CN104027458B (en) * | 2014-05-16 | 2016-11-23 | 中日友好医院 | A kind of pharmaceutical composition is for preparing the new application of antihyperglycemic hepatoprotective agent |
CN104117012A (en) * | 2014-06-13 | 2014-10-29 | 江美珍 | Traditional Chinese medicine for treating liver cirrhosis |
CN104399012B (en) * | 2014-12-16 | 2017-12-26 | 刘尚勤 | A kind of Chinese medicine composition for primary liver cancer |
CN105148197A (en) * | 2015-10-09 | 2015-12-16 | 房经富 | Medicine for treating fatty liver caused by qi stagnation and blood stasis and preparation method of medicine |
CN106177796A (en) * | 2016-08-30 | 2016-12-07 | 刘仪龙 | For treating the Chinese medicine composition of hepatitis B |
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