CN1102591A - Three-seedling compound mixture and formula thereof - Google Patents
Three-seedling compound mixture and formula thereof Download PDFInfo
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- CN1102591A CN1102591A CN 93115215 CN93115215A CN1102591A CN 1102591 A CN1102591 A CN 1102591A CN 93115215 CN93115215 CN 93115215 CN 93115215 A CN93115215 A CN 93115215A CN 1102591 A CN1102591 A CN 1102591A
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- herba
- hepatitis
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- 150000001875 compounds Chemical class 0.000 title claims abstract description 12
- 239000000203 mixture Substances 0.000 title claims abstract description 12
- 241000411851 herbal medicine Species 0.000 claims abstract description 10
- 241000222640 Polyporus Species 0.000 claims abstract description 8
- 239000010231 banlangen Substances 0.000 claims abstract description 8
- 210000003038 endothelium Anatomy 0.000 claims abstract description 8
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims abstract description 8
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims abstract description 7
- 241000628997 Flos Species 0.000 claims description 7
- 239000009636 Huang Qi Substances 0.000 claims description 7
- UAJTZZNRJCKXJN-UHFFFAOYSA-M sodium;2-dodecoxy-2-oxoethanesulfonate Chemical compound [Na+].CCCCCCCCCCCCOC(=O)CS([O-])(=O)=O UAJTZZNRJCKXJN-UHFFFAOYSA-M 0.000 claims description 7
- 241000756943 Codonopsis Species 0.000 claims description 6
- 229940124872 Hepatitis B virus vaccine Drugs 0.000 claims description 4
- 239000000796 flavoring agent Substances 0.000 claims description 4
- 235000019634 flavors Nutrition 0.000 claims description 4
- 229940041323 measles vaccine Drugs 0.000 claims description 3
- 102000039446 nucleic acids Human genes 0.000 claims description 3
- 108020004707 nucleic acids Proteins 0.000 claims description 3
- 229920001282 polysaccharide Polymers 0.000 claims description 3
- 239000005017 polysaccharide Substances 0.000 claims description 3
- 235000013372 meat Nutrition 0.000 claims 2
- 239000008139 complexing agent Substances 0.000 claims 1
- 241000700721 Hepatitis B virus Species 0.000 abstract description 8
- 208000002672 hepatitis B Diseases 0.000 abstract description 5
- 230000000144 pharmacologic effect Effects 0.000 abstract description 3
- 229960005486 vaccine Drugs 0.000 abstract 2
- 235000009051 Ambrosia paniculata var. peruviana Nutrition 0.000 abstract 1
- 241000205585 Aquilegia canadensis Species 0.000 abstract 1
- 235000003097 Artemisia absinthium Nutrition 0.000 abstract 1
- 240000001851 Artemisia dracunculus Species 0.000 abstract 1
- 235000017731 Artemisia dracunculus ssp. dracunculus Nutrition 0.000 abstract 1
- 235000003261 Artemisia vulgaris Nutrition 0.000 abstract 1
- 241001061264 Astragalus Species 0.000 abstract 1
- 241000007126 Codonopsis pilosula Species 0.000 abstract 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 abstract 1
- 244000303040 Glycyrrhiza glabra Species 0.000 abstract 1
- 241001571764 Lysimachia christinae Species 0.000 abstract 1
- 201000005505 Measles Diseases 0.000 abstract 1
- 235000017784 Mespilus germanica Nutrition 0.000 abstract 1
- 244000182216 Mimusops elengi Species 0.000 abstract 1
- 235000000560 Mimusops elengi Nutrition 0.000 abstract 1
- 240000001659 Oldenlandia diffusa Species 0.000 abstract 1
- 240000004980 Rheum officinale Species 0.000 abstract 1
- 235000008081 Rheum officinale Nutrition 0.000 abstract 1
- 240000006079 Schisandra chinensis Species 0.000 abstract 1
- 235000007837 Vangueria infausta Nutrition 0.000 abstract 1
- 239000001138 artemisia absinthium Substances 0.000 abstract 1
- 235000006533 astragalus Nutrition 0.000 abstract 1
- 235000013399 edible fruits Nutrition 0.000 abstract 1
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 abstract 1
- SPSXSWRZQFPVTJ-ZQQKUFEYSA-N hepatitis b vaccine Chemical compound C([C@H](NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CCSC)C(=O)N[C@@H](CC1N=CN=C1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)OC(=O)CNC(=O)CNC(=O)[C@H](C)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@@H](N)CCCNC(N)=N)C1=CC=CC=C1 SPSXSWRZQFPVTJ-ZQQKUFEYSA-N 0.000 abstract 1
- 229940124736 hepatitis-B vaccine Drugs 0.000 abstract 1
- 235000011477 liquorice Nutrition 0.000 abstract 1
- 230000008506 pathogenesis Effects 0.000 abstract 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 abstract 1
- 210000004233 talus Anatomy 0.000 abstract 1
- 239000007788 liquid Substances 0.000 description 9
- 239000003814 drug Substances 0.000 description 8
- 238000009835 boiling Methods 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 206010008909 Chronic Hepatitis Diseases 0.000 description 2
- 102000014150 Interferons Human genes 0.000 description 2
- 108010050904 Interferons Proteins 0.000 description 2
- 230000001154 acute effect Effects 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 208000006454 hepatitis Diseases 0.000 description 2
- 238000002649 immunization Methods 0.000 description 2
- 230000003053 immunization Effects 0.000 description 2
- 229940079322 interferon Drugs 0.000 description 2
- 239000006187 pill Substances 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- OIRDTQYFTABQOQ-UHTZMRCNSA-N Vidarabine Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O OIRDTQYFTABQOQ-UHTZMRCNSA-N 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 235000019994 cava Nutrition 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000009700 powder processing Methods 0.000 description 1
- 229920002477 rna polymer Polymers 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 229960003636 vidarabine Drugs 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
A three-vaccine compound mixture and a formula thereof are developed according to hepatitis B virus carrying (HBsAg positive) and pathogenesis of hepatitis B, and by combining Chinese and western medical theories and related pharmacological research. The three seedlings relate to a hepatitis B vaccine, a freeze-dried measles live vaccine and a Carti element, and are matched with 22 Chinese herbal medicines, namely 30-60 g of astragalus, 30-50 g of spreading hedyotis herb, 6-12 g of radix bupleuri, 3-9 g of rheum officinale, 30-90 g of Lysimachia christinae Hance, 15-30 g of endothelium corneum gigeriae galli, 15-30 g of poria, 15-30 g of polyporus, 30-60 g of liquorice, 15-30 g of radix asparagi, 15-20 g of medlar, 50-90 g of radix salviae miltiorrhizae, 20-40 g of Chinese magnoliavine fruit, 20-40 g of oriental wormwood, 30-60 g of radix isatidis, 15-20 g of pericarpium citri reticulatae, 15-30 g of codonopsis pilosula, 15-30 g of honeysuckle, 15-30 g of radix paeoniae alba, 15-30 g of polygon.
Description
The present invention relates to adopt the therapy of combining Chinese and Western medicine method, the Comprehensive Treatment hepatitis B virus carries and the " Sanmiao " compound mixture and the prescription thereof of B-mode acute, chronic hepatitis.
Now, the medicine that the treatment hepatitis B virus carries (the HBsAg positive) and hepatitis B is all more single, and toxic and side effects is big, and the course of treatment is long.As use interferon, and polyporusum bellatus adds Hepatitis B virus vaccine, vidarabine and anti-hepatitis B immune ribonucleic acid etc., and cure rate is lower.
The objective of the invention is to, overcome the deficiencies in the prior art part, provide a kind of Comprehensive Treatment hepatitis B virus to carry and the " Sanmiao " compound mixture and the prescription thereof of B-mode acute, chronic hepatitis.
The technical scheme of " Sanmiao " compound mixture of the present invention and prescription thereof is as follows: " Sanmiao " compound mixture of the present invention and prescription thereof, be the pathogeny of carrying (the HBsAg positive) and hepatitis B according to hepatitis B virus, in conjunction with the development of Chinese and western medicine theory and relevant pharmacological research.The prescription of " Sanmiao " compound mixture mainly is three Seedlings, and promptly Hepatitis B virus vaccine, cryodesiccant live measles vaccine and BCG-polysaccharide nucleic acid are used by existing using method.Be equipped with 22 flavor Chinese herbal medicine in addition, the prescription of Chinese medicine is: the Radix Astragali 30~60 grams, Herba Hedyotidis Diffusae 30~50 grams, Radix Bupleuri 6~12 grams, Radix Et Rhizoma Rhei 3~9 grams, Herba Lysimachiae 30~90 grams, Endothelium corneum 15~30 grams, Poria 15~30 grams, Polyporus 15~30 grams, Radix Glycyrrhizae 30~60 grams, Radix Asparagi 15~30 grams, Fructus Lycii 15~20 grams, Radix Salviae Miltiorrhizae 50~90 grams, Fructus Schisandrae Chinensis 20~40 grams, Herba Artemisiae Scopariae 20~40 grams, Radix Isatidis 30~60 grams, Pericarpium Citri Reticulatae 15~30 grams, Flos Lonicerae 15~30 grams, the Radix Paeoniae Alba 15~30 grams, Rhizoma Polygoni Cuspidati 15~30 grams, Herba Houttuyniae 15~30 grams, Fructus Corni 15~30 grams, decocting is for oral administration.Chinese herbal medicine formula described here, Herba Hedyotidis Diffusae, the Radix Astragali, Radix Salviae Miltiorrhizae, Polyporus, Radix Glycyrrhizae, Fructus Schisandrae Chinensis, Radix Asparagi, Fructus Corni, Endothelium corneum, Radix Codonopsis and Fructus Lycii should be decocted first during decocting, decoct and add Radix Et Rhizoma Rhei, Radix Bupleuri, Herba Lysimachiae, Herba Houttuyniae, Pericarpium Citri Reticulatae, Flos Lonicerae, Rhizoma Polygoni Cuspidati, Radix Isatidis, Herba Artemisiae Scopariae, the Radix Paeoniae Alba after 20 minutes, decocting 15 minutes again is that pourable medicinal liquid is standby.
Use " Sanmiao " compound mixture of the present invention and prescription thereof, easy to use, have no side effect, clinical trial certificate the cure rate and the improvement rate of hepatitis B virus carrier and hepatitis B all is higher than other medicines, and price significantly is lower than other drug.The comprehensive pharmacological action of " Sanmiao " compound mixture is, improves the cellular immunization and the humoral immunization ability of patient self human body, induces the generation endogenous interferon, suppresses duplicating and the growth of hepatocarcinoma of hepatitis B virus effectively, and then kills hepatitis B virus.
Now in conjunction with the embodiments " Sanmiao " compound mixture of the present invention and prescription thereof are further described: three Seedlings of the present invention, be meant Hepatitis B virus vaccine, cryodesiccant live measles vaccine and BCG-polysaccharide nucleic acid are used by existing using method, preferably adopt enclosure method to use.During sealing, acupoint selection position tsu san li, the sea of blood, bl, tan shu, Pishu seal three caves at every turn, and sealing in per two days once circulates in order and seals.Traditional Chinese medicine liquid of the present invention for oral administration simultaneously.Chinese herbal medicine formula of the present invention, get the Radix Astragali 30~60 grams, Herba Hedyotidis Diffusae 30~50 grams, Radix Bupleuri 6~12 grams, Radix Et Rhizoma Rhei 3~9 grams, Herba Lysimachiae 30~90 grams, Endothelium corneum 15~30 grams, Poria 15~30 grams, Polyporus 15~30 grams, Radix Glycyrrhizae 30~60 grams, Radix Asparagi 15~30 grams, Fructus Lycii 15~20 grams, Radix Salviae Miltiorrhizae 50~90 grams, Fructus Schisandrae Chinensis 20~40 grams, Herba Artemisiae Scopariae 20~40 grams, Radix Isatidis 30~60 grams, Pericarpium Citri Reticulatae 15~20 grams, Radix Codonopsis 15~30 grams, Flos Lonicerae 15~30 grams, the Radix Paeoniae Alba 15~30 grams, Rhizoma Polygoni Cuspidati 15~30 grams, Herba Houttuyniae 15~30 grams, Fructus Corni 15~30 grams, watered boiling, processor is to put into Herba Hedyotidis Diffusae earlier, the Radix Astragali, Radix Salviae Miltiorrhizae, Poria, Polyporus, Radix Glycyrrhizae, Fructus Schisandrae Chinensis, Radix Asparagi, Fructus Corni, Endothelium corneum, Radix Codonopsis and Fructus Lycii, decoct and add Radix Et Rhizoma Rhei after 20 minutes, Radix Bupleuri, Herba Lysimachiae, Herba Houttuyniae, Pericarpium Citri Reticulatae, Flos Lonicerae, Rhizoma Polygoni Cuspidati, Radix Isatidis, Herba Artemisiae Scopariae, the Radix Paeoniae Alba, decoct and got final product in 15 minutes, well-done amount of liquid medicine is advisable with 500 milliliters.Chinese herbal medicine formula described here, optimum is, get the Radix Astragali 30 grams, Herba Hedyotidis Diffusae 30 grams, Radix Bupleuri 10 grams, Radix Et Rhizoma Rhei 6 grams, Herba Lysimachiae 30 grams, Endothelium corneum 20 grams, Poria 15 grams, Polyporus 15 grams, Radix Glycyrrhizae 30 grams, Radix Asparagi 20 grams, Fructus Lycii 15 grams, Radix Salviae Miltiorrhizae 60 grams, Fructus Schisandrae Chinensis 30 grams, Herba Artemisiae Scopariae 30 grams, Radix Isatidis 30 grams, Pericarpium Citri Reticulatae 15 grams, Radix Codonopsis 15 grams, Flos Lonicerae 15 grams, the Radix Paeoniae Alba 30 grams, Rhizoma Polygoni Cuspidati 20 grams, Herba Houttuyniae 30 grams, Fructus Corni 15 grams, decoct by processor of the present invention, taking liquid is standby.
According to Chinese herbal medicine formula of the present invention, convert decocting and become medicinal liquid to be advisable with 500 milliliters, take for twice on the one.Watered boiling again in second day is advisable with 500 milliliters, takes for twice on the one.Also can become 500 milliliters of medicinal liquids by Chinese herbal medicine formula watered boiling of the present invention, pour out medicinal liquid after, watered boiling becomes 500 milliliters of medicinal liquids again, twice fried medicinal liquid merges the back and takes by two days 4 times.According to above-mentioned dosage, can make pill with existing program of making pill, also can make powder by existing powder processing technology.
Claims (2)
1, " Sanmiao " compound mixture and prescription thereof, include Hepatitis B virus vaccine, cryodesiccant live measles vaccine, BCG-polysaccharide nucleic acid and 22 flavor Chinese herbal medicine are formed, and it is characterized in that described 22 flavor Chinese herbal medicine are the Radix Astragali 30~60 grams, Herba Hedyotidis Diffusae 30~50 grams, Radix Bupleuri 6~12 grams, Radix Et Rhizoma Rhei 3~9 grams, Herba Lysimachiae 30~90 grams, Endothelium corneum 15~30 grams, Poria 15~30 grams, Polyporus 15~30 grams, Radix Glycyrrhizae 30~60 grams, Radix Asparagi 15~30 grams, Fructus Lycii 15~20 grams, Radix Salviae Miltiorrhizae 50~90 grams, Fructus Schisandrae Chinensis 20~40 grams, Herba Artemisiae Scopariae 20~40 grams, Radix Isatidis 30~60 grams, Pericarpium Citri Reticulatae 15~20 grams, Radix Codonopsis 15~30 grams, Flos Lonicerae 15~30 grams, the Radix Paeoniae Alba 15~30 grams, Rhizoma Polygoni Cuspidati 15~30 grams, Herba Houttuyniae 15~30 grams, mountain an ancient wind instrument meat 15~30 grams.
2, three Seedling complexing agent and prescriptions thereof according to claim 1, the optimum that it is characterized in that described 22 flavor Chinese herbal medicine are the Radix Astragali 30 grams, Herba Hedyotidis Diffusae 30 grams, Radix Bupleuri 10 grams, Radix Et Rhizoma Rhei 6 grams, Herba Lysimachiae 30 grams, Endothelium corneum 15 grams, Poria 15 grams, Polyporus 15 grams, Radix Glycyrrhizae 30 grams, Radix Asparagi 20 grams, Fructus Lycii 15 grams, Radix Salviae Miltiorrhizae 60 grams, Fructus Schisandrae Chinensis 30 grams, Herba Artemisiae Scopariae 30 grams, Radix Isatidis 30 grams, Pericarpium Citri Reticulatae 15 grams, Radix Codonopsis 15 grams, Flos Lonicerae 15 grams, the Radix Paeoniae Alba 30 grams, Rhizoma Polygoni Cuspidati 20 grams, Herba Houttuyniae 30 grams, mountain an ancient wind instrument meat 15 grams.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 93115215 CN1102591A (en) | 1993-11-06 | 1993-11-06 | Three-seedling compound mixture and formula thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN 93115215 CN1102591A (en) | 1993-11-06 | 1993-11-06 | Three-seedling compound mixture and formula thereof |
Publications (1)
Publication Number | Publication Date |
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CN1102591A true CN1102591A (en) | 1995-05-17 |
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN 93115215 Pending CN1102591A (en) | 1993-11-06 | 1993-11-06 | Three-seedling compound mixture and formula thereof |
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1061249C (en) * | 1997-04-10 | 2001-01-31 | 宣余发 | Quick-acting traditional Chinese medicine for curing hepatitis B |
CN1070378C (en) * | 1998-11-24 | 2001-09-05 | 雷玉宏 | Medicine for curing hepatitis B |
CN1081067C (en) * | 1999-12-06 | 2002-03-20 | 黄培乐 | Chinese medicine prescription for curing hepatitis, cholangitis, pancreatitis and cirrhosis |
CN1085548C (en) * | 1999-03-31 | 2002-05-29 | 广州医学院第二附属医院 | Traditional Chinese medicinal prepns. for treating hepatitis B virus, and method for preparing same |
CN102341114A (en) * | 2009-03-03 | 2012-02-01 | 加拿大瑞发生物科技制药集团 | Plant extract compositions for prevention and treatment of influenza |
-
1993
- 1993-11-06 CN CN 93115215 patent/CN1102591A/en active Pending
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1061249C (en) * | 1997-04-10 | 2001-01-31 | 宣余发 | Quick-acting traditional Chinese medicine for curing hepatitis B |
CN1070378C (en) * | 1998-11-24 | 2001-09-05 | 雷玉宏 | Medicine for curing hepatitis B |
CN1085548C (en) * | 1999-03-31 | 2002-05-29 | 广州医学院第二附属医院 | Traditional Chinese medicinal prepns. for treating hepatitis B virus, and method for preparing same |
CN1081067C (en) * | 1999-12-06 | 2002-03-20 | 黄培乐 | Chinese medicine prescription for curing hepatitis, cholangitis, pancreatitis and cirrhosis |
CN102341114A (en) * | 2009-03-03 | 2012-02-01 | 加拿大瑞发生物科技制药集团 | Plant extract compositions for prevention and treatment of influenza |
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