CN1061249C

CN1061249C - Quick-acting traditional Chinese medicine for curing hepatitis B

Info

Publication number: CN1061249C
Application number: CN97109067A
Authority: CN
Inventors: 宣余发
Original assignee: Individual
Current assignee: Individual
Priority date: 1997-04-10
Filing date: 1997-04-10
Publication date: 2001-01-31
Anticipated expiration: 2017-04-10
Also published as: CN1195544A

Abstract

The present invention relates to traditional Chinese medicine for quickly treating chronic hepatitis B. The traditional Chinese medicine is prepared from poria, astragalus root, Chinese yam, raw malt, forsythia fruit, mint, largehead atractylodes rhizome, bupleurum root, bushy knotweed root, cassia twig, white peony root and ephedra, and the traditional Chinese medicine can be prepared into decoction, concentrated liquid, capsules and pills. Medicine with the functions of supplementing the spleen and kidney and improving the immunity of human bodies, such as astragalus root, poria, bupleurum root, etc. is mainly used in the traditional Chinese medicine of the present invention. The present invention has the advantages of good curative effect, short treatment course and high curative rate for treating chronic hepatitis B, and a total effective rate is more than 98%.

Description

A kind of medicine for the treatment of hepatitis B

The present invention relates to a kind of Chinese medicine for oral administration, a kind of specifically medicine for the treatment of hepatitis B.

The chronic viral hepatitis B patient fails to cure delay by suffering from acute hepatitis b; Or inherent (parent carries infection); Or health is carried disease germs but show symptom when passive protective physical fitness is relatively poor, its common trait show as " positive weakness of QI or a little less than; can not rouse heresy and go out ", the hepatitis B infected sustainable several years of back, clinical symptoms is very unobvious, very harmful, western medical treatment is based on anti-hepatitis virus, and the course of treatment is long, the expense height, curative effect is not high, and side effect is big; The rule that the Chinese traditional treatment hepatitis B then more to be adopted " the liver being liable to excess, have let out of no help " adopts or rushes down down, or the method for heavy dose of heat-clearing and toxic substances removing, often causes healthy energy impaired, and immunologic hypofunction, cure rate and effective percentage are also not high.And show according to studying for a long period of time: the positive weakness of QI of chronic viral hepatitis B or a little less than, trace sth. to its source, duty in the spleen kidney deficiency, cause the liver failing to be nourished, add the stagnation of liver-QI QI rising in reverse order; Catharsis is not normal, and unable liter looses, and the drum heresy is gone out, so that the epidemic disease poison is detained in the body, slowly is difficult to eliminate, liver is a viscus attriguted to wind and wood, and its property liter is sent out, and is not held back strongly fragrantly, and happiness is transferred and to be reached, and the liter of right liver is sent out the nourishing that depends on kidney water, the spleen earth culture it, can rise and send out constant, catharsis is transferred smooth, satisfies the meaning of its growth.Otherwise, or be high or for pent-up, the then depression of liver-QI that belong to of the chronic viral hepatitis B cause of disease more, Yu Ze involves kidney downwards through QI rising in reverse order, involve spleen soil left, edema with the liver involved of a specified duration is lost and is grown, cervical carcinoma with cachexia a little less than must causing, be the more important thing is its intrinsic factor: promptly a little less than the irritability element, be difficult to circulation, certainly can not dredge spleen soil, and occur indigestion and loss of appetite, (this point thinks traditionally that with middle medical circles edema with the liver involved can only be high excessively to symptoms such as abdominal distention, it is distinct that wood cuts down spleen soil), kidney liter waterborne relies the assistance that sent out by the irritability liter again, and it is constant to rise, and right edema with the liver involved rises to send out haves no right, symptoms such as the lower limb that occur so appearance can not be drawn kidney liter waterborne are aching and limp, and the whole body is weak.

Purpose of the present invention aims to provide a kind of the kidney invigorating and contains Chinese medicine wooden, that ridging honor is native, tonifying liver rises the treatment chronic viral hepatitis B diffusing, that the drum heresy is gone out.

The present invention seeks to realize in the following manner: a kind of medicine for the treatment of hepatitis B, to make by Poria, the Radix Astragali, Rhizoma Dioscoreae, Fructus Hordei Germinatus, Fructus Forsythiae, Herba Menthae, the Rhizoma Atractylodis Macrocephalae, Radix Bupleuri, Rhizoma Polygoni Cuspidati, Ramulus Cinnamomi, the Radix Paeoniae Alba and Herba Ephedrae, each proportioning raw materials (weight portion) is:

Poria 25-30 Radix Astragali 30-45 Rhizoma Dioscoreae 12-16 Fructus Hordei Germinatus 6-12

Fructus Forsythiae 12-20 Herba Menthae 12-20 Rhizoma Atractylodis Macrocephalae 10-15 Radix Bupleuri 6-10

Rhizoma Polygoni Cuspidati 12-14 Ramulus Cinnamomi 9-12 Radix Paeoniae Alba 6-8 Herba Ephedrae 6-9

A kind of medicine for the treatment of chronic viral hepatitis B is made by Poria, the Radix Astragali, Rhizoma Dioscoreae, Fructus Hordei Germinatus, Fructus Forsythiae, Herba Menthae, the Rhizoma Atractylodis Macrocephalae, Radix Bupleuri, Rhizoma Polygoni Cuspidati, Ramulus Cinnamomi, the Radix Paeoniae Alba, Herba Ephedrae, Herba Artemisiae Scopariae and Semen Plantaginis, and each proportioning raw materials (weight portion) is:

Herba Artemisiae Scopariae 6-9 Semen Plantaginis 10-15

This medicine can be made into decoction, concentrated juice, pill or capsule.

The method of production medicine decoction of the present invention:

A, get and obtain Siberian cocklebur, the Radix Astragali, Rhizoma Dioscoreae, Fructus Forsythiae, the Rhizoma Atractylodis Macrocephalae, Radix Bupleuri, Rhizoma Polygoni Cuspidati, Ramulus Cinnamomi, the Radix Paeoniae Alba, Semen Plantaginis earlier with 400ml cold water soak 1 hour, standby;

B, get Herba Ephedrae, put into jar and add 100ml cold water, skimming after being fried boiling 5 minutes;

C, its cold water of Poria, the Radix Astragali, Rhizoma Dioscoreae, Fructus Forsythiae, the Rhizoma Atractylodis Macrocephalae, Radix Bupleuri, Rhizoma Polygoni Cuspidati, Ramulus Cinnamomi, the Radix Paeoniae Alba, Semen Plantaginis and immersion added in the Herba Ephedrae jar boil 20 minutes at a simmer of reuse with big fire; Following Herba Artemisiae Scopariae, Fructus Hordei Germinatus boiled 5 minutes; Descend at last Herba Menthae to boil 3 minutes, filtering residue promptly gets required decoction.

The method of production medicine concentrated juice of the present invention:

Get Poria, the Radix Astragali, Rhizoma Dioscoreae, Fructus Forsythiae, the Rhizoma Atractylodis Macrocephalae, Radix Bupleuri, Rhizoma Polygoni Cuspidati, Ramulus Cinnamomi, the Radix Paeoniae Alba and Semen Plantaginis earlier, standby with 400ml cold water soak 2-3 hour;

Skimming added its cold water of Poria, the Radix Astragali, Rhizoma Dioscoreae, Fructus Forsythiae, the Rhizoma Atractylodis Macrocephalae, Radix Bupleuri, Rhizoma Polygoni Cuspidati, Ramulus Cinnamomi, the Radix Paeoniae Alba, Semen Plantaginis and immersion after Herba Ephedrae added 100ml cold water and be fried boiling 5 minutes, change slow fire after being fried boiling with big fire and endured 50 minutes, continue and include Herba Artemisiae Scopariae in, Fructus Hordei Germinatus was fried boiling 15 minutes; Add Herba Menthae again and be fried boiling 3-5 minute, the filtered while hot medicinal liquid is also built, and is ventilative, make it the nature cold concentrated juice.

The method of production medicament capsule of the present invention: get the concentrated juice for preparing, add fecula and mix thoroughly, be pressed into constantly to grind in the 20 purpose ferrum sieve and rub, make it into granule, grind into powder behind the natural airing, " 0 " number capsule of packing into, the proportioning of concentrated juice and fecula (weight portion) is: concentrated juice 70, fecula 30.

The method of production bolus of drug of the present invention: the concentrated juice for preparing is mixed with fecula, adding distil water is mixed thoroughly, and the method for making water pill is routinely made a ball and got final product, and the proportioning of concentrated juice, fecula and distilled water (weight portion) is: concentrated juice 60, fecula 32, distilled water 8.

In the medicine of the present invention, Rhizoma Dioscoreae the kidney invigorating water deficiency, the energy of holder kidney is up; With the gas of Fructus Hordei Germinatus, the rapid hair growth promoting liver of Herba Artemisiae Scopariae and kidney tonifying, essence replenishing and not dry greasy; Rhizoma Dioscoreae, the Radix Astragali, Poria, Rhizoma Atractylodis Macrocephalae spleen invigorating are earthed up with Rong Mu; The Radix Astragali is joined the gas of Ramulus Cinnamomi tonifying liver; Radix Bupleuri, Herba Artemisiae Scopariae rise the gas of sending out liver, join the dense heat in Semen Plantaginis, Rhizoma Polygoni Cuspidati, the Herba Menthae liver heat removing, and using corrigent Radix Bupleuri rises and send out excessively, have to rise to have and fall, and guarantee the light gas rising of liver, and Herba Menthae has the merit of therapeutic method to keep the adverse QI flowing downwards relieving distension simultaneously; Herba Ephedrae, Fructus Forsythiae lung qi dispersing, make liver light gas remy hair and on, and assist the enraged epidemic disease of liver and go out external; The Radix Paeoniae Alba is upwards refluxed to protect the liver blood, synchronous with irritability, tonifying liver remy hair, recent studies show that major part has the function that improves immunity in various degree in the spleen reinforcing kidney medicine, and the chronic viral hepatitis B patient is exactly the disease based on hypoimmunity, medicines such as the Radix Astragali, Poria, Radix Bupleuri, the Rhizoma Atractylodis Macrocephalae, Rhizoma Dioscoreae, the very remarkable and short treating period of effect, instant effect have been reused to the property of the present invention is directed to, the cure rate height, following mask body is discussed this curative effect of medication.

1993.8-1996.12, treat 368 routine chronic viral hepatitis B patients altogether, male's 170 examples wherein, women's 198 examples, at 9 years old-69 years old age, period of disease is all used Drug therapy of the present invention from 0.5-8, and the treatment situation sees Table 1: table 1

Project	Before the treatment several unusually (examples)	Positive constant % is recovered in the treatment back	Treatment back recovery normal time (my god)/percentage ratio
								?10	?20	?30	?40	More than 40
			SGPT	?128	?100	?81.25	?18.75	?10	?20	?30	?40	More than 40	?0	?0	?0
HBSAG	?368	?98.9	SGPT	?128	?100	?81.25	?18.75	?21.2	?51.63	?13	?10.59	?2.45	?0	?0	?0
HBSAG	?368	?98.9	Anti--HBC	?368	?100	?21.2	?44.83	?21.2	?51.63	?13	?10.59	?2.45	?23.9	?8.91	?1.08
Anti--HBC	?306	?100	Anti--HBC	?368	?100	?21.2	?44.83	?25.5	?39.54	?33.66	?1.3		?23.9	?8.91	?1.08

Sum up: cure rate is 98.9%, invalid 1.1%.

The medication group and clothes Beijing Chaoyang ball conventional therapy contrast groups of table 2 for taking this: (30 days) table 2

Group	Number	Cure	Effectively	Invalid
Group	Number	Cure	Effectively	Invalid	The medication group	100	?62	?35	?3
Contrast groups	100	?6	?21	?73	The medication group	100	?62	?35	?3

Sum up: with treatments such as conventional Chaoyang balls, effective percentage only is 27%, treats total effective rate then up to 97% with this medicine.

Embodiment one: decoction

It is standby that Poria 25g, Radix Astragali 45g, Rhizoma Dioscoreae 13g, Fructus Forsythiae 12g, Rhizoma Atractylodis Macrocephalae 12g, Radix Bupleuri 8g, Rhizoma Polygoni Cuspidati 12g, Ramulus Cinnamomi 9g, Radix Paeoniae Alba 8g, Semen Plantaginis 10g are added 400ml cold water soak 1 hour;

Get Herba Ephedrae 6g, skimming after adding 100ml cold water and being fried boiling 5 minutes in going into;

Medicines such as soaked Poria are connected water add in the dress Herba Ephedrae jar, after big fire is boiled 20 minutes at a simmer again; Following Herba Artemisiae Scopariae, Fructus Hordei Germinatus boiled 5 minutes; Descend at last mentha leave to boil 3 minutes, filtering residue promptly gets required decoction.

Embodiment two: concentrated juice

Earlier that Poria 30g, Radix Astragali 45g, Rhizoma Dioscoreae 16g, Fructus Forsythiae 20g, Rhizoma Atractylodis Macrocephalae 15g, Radix Bupleuri 10g, Rhizoma Polygoni Cuspidati 14g, Ramulus Cinnamomi 10g, Radix Paeoniae Alba 8g, Semen Plantaginis 15g is standby with 400ml cold water soak 2-3 hour;

The 6g Herba Ephedrae is added 100ml cold water be fried boiling medicine and water such as adding Poria after the skimming, changing slow fire after big fire is fried boiling endured 50-60 minute, continue and include Herba Artemisiae Scopariae 9g, Fructus Hordei Germinatus 12g in and be fried boiling 5 minutes, add mentha leave at last and be fried boiling 3-5 minute, filtered while hot gets final product gained medicinal liquid airing.

Embodiment three: capsule

Get embodiment 2 and produce good concentrated juice 70g, add the 20g fecula to mix thoroughly, be pressed into the interior constantly mill of 20 purpose ferrum sieve and rub, make it into granule, grind into powder behind the natural airing, " 0 " number capsule of packing into, the proportioning of concentrated juice and fecula (weight portion) is: concentrated juice 70, fecula 30.

Embodiment four: pill

Get and produce good concentrated juice 60g, add the 32g fecula, the 8g distilled water is mixed thoroughly, pill.

Claims

1. medicine for the treatment of hepatitis B is characterized in that this Chinese medicine made by Poria, the Radix Astragali, Rhizoma Dioscoreae, Fructus Hordei Germinatus, Fructus Forsythiae, Herba Menthae, the Rhizoma Atractylodis Macrocephalae, Radix Bupleuri, Rhizoma Polygoni Cuspidati, Ramulus Cinnamomi, the Radix Paeoniae Alba and Herba Ephedrae, and each proportioning raw materials weight portion is:

2. medicine for the treatment of hepatitis B is characterized in that this Chinese medicine made by Poria, the Radix Astragali, Rhizoma Dioscoreae, Fructus Hordei Germinatus, Fructus Forsythiae, Herba Menthae, the Rhizoma Atractylodis Macrocephalae, Radix Bupleuri, Rhizoma Polygoni Cuspidati, Ramulus Cinnamomi, the Radix Paeoniae Alba, Herba Ephedrae, Herba Artemisiae Scopariae and Semen Plantaginis, and each proportioning raw materials weight portion is:

Herba Artemisiae Scopariae 6-9 Semen Plantaginis 10-15

3. the medicine of treatment hepatitis B according to claim 1 and 2 is characterized in that this medicine can be made into decoction, concentrated juice, pill or capsule.

4. produce the method for the medicine decoction of treatment hepatitis B as claimed in claim 3, it is characterized in that:

A, get Poria, the Radix Astragali, Rhizoma Dioscoreae, Fructus Forsythiae, the Rhizoma Atractylodis Macrocephalae, Radix Bupleuri, Rhizoma Polygoni Cuspidati, Ramulus Cinnamomi, the Radix Paeoniae Alba, Semen Plantaginis with 400ml cold water soak 1 hour earlier, standby;

5. produce the method for the medicine concentrated juice of treatment hepatitis B as claimed in claim 3, it is characterized in that:

Get Poria, the Radix Astragali, Rhizoma Dioscoreae, Fructus Forsythiae, the Rhizoma Atractylodis Macrocephalae, Radix Bupleuri, Rhizoma Polygoni Cuspidati, Ramulus Cinnamomi, the Radix Paeoniae Alba and Semen Plantaginis earlier, standby with 400ml cold water soak 2-3 hour; Skimming added its cold water of Poria, the Radix Astragali, Rhizoma Dioscoreae, Fructus Forsythiae, the Rhizoma Atractylodis Macrocephalae, Radix Bupleuri, Rhizoma Polygoni Cuspidati, Ramulus Cinnamomi, the Radix Paeoniae Alba, Semen Plantaginis and immersion after Herba Ephedrae added 100ml cold water and be fried boiling 5 minutes, change slow fire after being fried boiling with big fire and endured 50 minutes, continue and include Herba Artemisiae Scopariae in, Fructus Hordei Germinatus was fried boiling 15 minutes; Add Herba Menthae again and be fried boiling 3-5 minute, the filtered while hot medicinal liquid is also built, and is ventilative, make it the nature cold concentrated juice.

6. produce the method for the medicament capsule of treatment hepatitis B as claimed in claim 3, it is characterized in that: get the concentrated juice for preparing as claim 5 production method, adding fecula mixes thoroughly, be pressed into constantly to grind in the 20 purpose ferrum sieve and rub, make it into granule, grind into powder behind the natural airing, " 0 " number capsule of packing into, the proportioning weight portion of concentrated juice and fecula is: concentrated juice 70, fecula 30.

7. produce the method for the bolus of drug of treatment hepatitis B as claimed in claim 3, it is characterized in that: will mix with fecula as the concentrated juice that method as described in the claim 5 prepares, adding distil water is mixed thoroughly, the method of making water pill is routinely made a ball and is got final product, the proportioning weight portion of concentrated juice, fecula and distilled water is: concentrated juice 60, fecula 32, distilled water 8.