CN101953943A - Traditional Chinese medicine for treating chronic aplastic anemia - Google Patents

Traditional Chinese medicine for treating chronic aplastic anemia Download PDF

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Publication number
CN101953943A
CN101953943A CN 201010291059 CN201010291059A CN101953943A CN 101953943 A CN101953943 A CN 101953943A CN 201010291059 CN201010291059 CN 201010291059 CN 201010291059 A CN201010291059 A CN 201010291059A CN 101953943 A CN101953943 A CN 101953943A
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radix
traditional chinese
chinese medicine
aplastic anemia
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王兴启
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Abstract

The invention relates to a traditional Chinese medicament for treating chronic aplastic anemia. The traditional Chinese medicament is characterized in that: decoction comprises 20 grams of amur corktree bark, 80 grams of suberect spatholobus stem, 15 grams of virgate worm wood herb, 20 grams of largehead atractylodes rhizome, 20 grams of astragalus, 15 grams of mint, 20 grams of figwort root, 30 grams of dandelion and 30 grams of hematite; and pills comprise 100 grams of root of red-rooted salvia, 100 grams of tulip, 100 grams of flickingeria comata hawkes, 100 grams of mongolian snakegourd root, 100 grams of astragalus, 100 grams of tuber fleeceflower root, 100 grams of black alum and 50 grams of mirabilite; and the dose precision of the traditional Chinese medicament is +/-10 percent of each of the medicaments. The traditional Chinese medicament has the effect of nourishing liver and spleen, nourishing kidney and tonifying stomach, promoting blood circulation and enriching the blood, and quickly increasing the number of blood cells, hemoglobin and white blood cells without any toxic or side effect.

Description

A kind of Chinese medicine for the treatment of chronic aplastic anemia
Technical field
The present invention relates to a kind of medicine for the treatment of anemia, especially a kind of Chinese medicine for the treatment of chronic aplastic anemia.
Background technology
At present, chronic aplastic anemia is one group of marrow hematopoiesis function failure that is caused by Different types of etiopathogenises, is the intractable hematopathy of feature with hematopoietic stem cell injuries, peripheral blood pancytopenia, often shows as anemia, hemorrhage and infection clinically; This disease pathophysiological mechanism is very complicated, and the treatment difficulty is big, and easier initiation is complication widely; quite a few patient relies on long-term transfusion, and uses hormonal medicaments to alleviate sufferer and earn a bare living; but because of its immunity is low relatively, multiple complications causes in regular meeting, and therapeutic effect is unsatisfactory.
Summary of the invention
There are some unfavorable problems in order to solve in the chronic aplastic anemia treatment, the invention provides a kind of Chinese medicine for the treatment of chronic aplastic anemia, the Chinese medicine of this treatment chronic aplastic anemia utilizes invigorating kidney, promoting blood circulation, the principle of qi and blood tonifying is taken safety, stable curative effect, cure rate height, without any side effects.
Concrete proportioning of the present invention is:
One, the concrete proportioning of decoction: Cortex Phellodendri 20 gram, Caulis Spatholobi 80 grams, Herba Artemisiae Scopariae 15 grams, the Rhizoma Atractylodis Macrocephalae 20 grams, the Radix Astragali 20 grams, Herba Menthae 15 grams, Radix Scrophulariae 20 grams, Herba Taraxaci 30 grams, Haematitum 30 grams, the degree of accuracy of the dose of this Chinese medicine be each medicine ± 10%.
Two, the concrete proportioning of pill: Radix Salviae Miltiorrhizae 100 gram, Flos Tulipae Gesnerianae 100 grams, Ephemerantha lonchophylla (Hook. F) Hunt et Sum-merh. [Ephemerantha fimbrate (Bl.) Hunt et Summerh. 100 grams, Radix Trichosanthis 100 grams, the Radix Astragali 100 grams, Radix Polygoni Multiflori 100 grams, Alumen preparata 100 grams, Natrii Sulfas 50 grams, the degree of accuracy of the dose of this Chinese medicine be each medicine ± 10%.
Pharmacology of the present invention is: Cortex Phellodendri: heat clearing and damp drying, pathogenic fire purging are removed and are steamed, and skin ulcer is treated in detoxifcation; Caulis Spatholobi: enrich blood, invigorate blood circulation, collateral dredging; Herba Artemisiae Scopariae: function of gallbladder promoting hepatoprotective, antiinflammatory are analgesic, the effect of blood fat-reducing blood pressure-decreasing, anticoagulation; The Rhizoma Atractylodis Macrocephalae: invigorating the spleen and benefiting QI, the dehumidifying benefit is dry; The Radix Astragali: enhancing human body immunity function, blood pressure lowering protect the liver, diuresis, defying age, and antibacterial action more widely; Herba Menthae: sweating and heat resolving,, rash detoxifcation, dispersing the stagnated live-QI to relieve the stagnation of QI; Radix Scrophulariae: clearing away heat and cooling blood, eliminating fire and detoxication; Herba Taraxaci: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds; Haematitum: heat-clearing and toxic substances removing, QI invigorating regulating QI; Radix Salviae Miltiorrhizae: promoting blood circulation and cooling blood, stasis-dispelling and pain-killing, nourishing blood to tranquillize the mind; Flos Tulipae Gesnerianae: dissipating depression of QI dispelling stagnant Qi; Ephemerantha lonchophylla (Hook. F) Hunt et Sum-merh. [Ephemerantha fimbrate (Bl.) Hunt et Summerh.: reinforcing stomach reg fluid, replenishing YIN and removing heat; Radix Trichosanthis: clearing away heat-fire, promoting the production of body fluid to quench thirst, evacuation of pus detumescence; Radix Polygoni Multiflori: enrich and benefit essence and blood, bone and muscle strengthening, invigorating the liver and kidney; Alumen preparata: detoxifcation heat extraction; Natrii Sulfas: purging heat to relax the bowels, moistening for dryness and softening hard mass, the detumescence of relieving inflammation or internal heat.
Preparing process of the present invention:
One, decoction preparing process: fry standby in order to little fire the Rhizoma Atractylodis Macrocephalae, the Rhizoma Atractylodis Macrocephalae and Cortex Phellodendri, Caulis Spatholobi, Herba Artemisiae Scopariae, the Radix Astragali, Herba Menthae, Radix Scrophulariae, Herba Taraxaci, Haematitum after will frying then are mixed into pot, slowly endure with clear water slow fire, treat that decoction is fried in shallow oil and to put into Herba Menthae after ripe, after 3 minutes, removing slag takes concoction, and treats to take behind the room temperature.
Two, the preparing process of pill: Radix Salviae Miltiorrhizae is gone into pot, spray is fried dried standby after drinking, Radix Salviae Miltiorrhizae is 10: 1 with the amount ratio of Chinese liquor, the Radix Salviae Miltiorrhizae of frying after doing is put into sieve with Flos Tulipae Gesnerianae, Ephemerantha lonchophylla (Hook. F) Hunt et Sum-merh. [Ephemerantha fimbrate (Bl.) Hunt et Summerh., Radix Trichosanthis, the Radix Astragali, Radix Polygoni Multiflori, Alumen preparata, Natrii Sulfas, dash with cool matter clear water sieve, pull the back oven dry out, grind to form fine powder, machine is made pill and is got final product.
Administrated method of the present invention is: oral decoction: above-mentioned decoction proportioning is one day a taking dose, one day twice, sooner or later respectively once.Oral administration pills: every day twice, each 4-5 gram.
The invention has the beneficial effects as follows: the Chinese medicine tonifying liver spleen of this kind treatment chronic aplastic anemia, the nourishing kidney stomach reinforcing, blood circulation promoting and enriching, qi and blood tonifying, fast lifting platelet, hemoglobin and leukocytic quantity, without any side effects.
Specific embodiment
Through over 4 years, the clinical practice to 100 examples are treated the patient of chronic aplastic anemia diseases has obtained curative effect preferably, and total effective rate reaches 95%, and details are as follows for relevant clinical treatment situation:
1. patient profile: select projects such as medical history, the state of an illness, age, sex and original therapy method.
2. patient originates: with general hospital patient and professional OH patient.
3. case is gone into the group standard, and according to the clinical manifestation and the pathological characters branch of treatment chronic aplastic anemia disease, sex, age are not limit, and the course of disease is more than 1 year; Inactive various other medicines and therapeutic modality before the treatment.
4. preparing process: decoction preparing process: fry standby in order to little fire the Rhizoma Atractylodis Macrocephalae, the Rhizoma Atractylodis Macrocephalae and Cortex Phellodendri, Caulis Spatholobi, Herba Artemisiae Scopariae, the Radix Astragali, Herba Menthae, Radix Scrophulariae, Herba Taraxaci, Haematitum after will frying then are mixed into pot, slowly endure with clear water slow fire, treat that decoction is fried in shallow oil and to put into Herba Menthae after ripe, after 3 minutes, removing slag takes concoction, and treats to take behind the room temperature; The preparing process of pill: Radix Salviae Miltiorrhizae is gone into pot, spray is fried dried standby after drinking, Radix Salviae Miltiorrhizae is 10: 1 with the amount ratio of Chinese liquor, Radix Salviae Miltiorrhizae and Flos Tulipae Gesnerianae, Ephemerantha lonchophylla (Hook. F) Hunt et Sum-merh. [Ephemerantha fimbrate (Bl.) Hunt et Summerh., Radix Trichosanthis, the Radix Astragali, Radix Polygoni Multiflori, Alumen preparata, the Natrii Sulfas fried after doing are dashed with cool matter clear water sieve, pull the back oven dry out, grind to form fine powder, machine is made pill and is got final product.
5. administrated method: oral decoction: with the taking dose of above-mentioned decoction proportioning as one day, one day twice, each was once sooner or later.Oral administration pills: every day twice, each 4-5 gram.
6. efficacy evaluation
1. recovery from illness: sufferer transference cure, thoroughly recovery from illness.
2. remarkable: as more than curing later six months recurrence not to be arranged.
3. effective: anemia, infection, bleeding significantly reduce.
4. invalid: change not quite before and after the treatment, or once taking a turn for the better, after return to symptom before the treatment again.
7. efficacy analysis:
1. sex: according to going into the group standard, we treat chronic aplastic anemia disease patient 100 examples altogether, male's 60 examples (60%) wherein, women's 40 examples (40%).
2. the course of disease: 1 year~3 years is 30 examples, and 4 years~5 years is 40 examples, is 30 examples more than 5 years.
3. age group: 16~20 years old 20 example, 21~30 years old 5 example, 31~40 years old 5 example, 41~50 years old 20 example, 51~60 years old 25 example, 25 examples more than 60 years old.
4. prepare the dose scheme for first kind: the concrete proportioning of decoction: Cortex Phellodendri 20 restrains, Caulis Spatholobi 80 restrains, Herba Artemisiae Scopariae 15 restrains, the Rhizoma Atractylodis Macrocephalae 20 restrains, the Radix Astragali 20 restrains, Herba Menthae 15 restrains, Radix Scrophulariae 20 restrains, Herba Taraxaci 30 restrains, Haematitum 30 restrains.
The concrete proportioning of pill: Radix Salviae Miltiorrhizae 100 grams, Flos Tulipae Gesnerianae 100 grams, Ephemerantha lonchophylla (Hook. F) Hunt et Sum-merh. [Ephemerantha fimbrate (Bl.) Hunt et Summerh. 100 grams, Radix Trichosanthis 100 grams, the Radix Astragali 100 grams, Radix Polygoni Multiflori 100 grams, Alumen preparata 100 grams, Natrii Sulfas 50 grams.
The efficacy analysis of this scheme, administration time are 1~2 course of treatment.
Patient's type Recovery from illness Significantly Effectively Invalid
Patients with mild 50 examples 40 7 2 1
Moderate patient's 35 examples 30 2 2 1
Severe patient 15 examples 11 2 1 1
The scheme of second kind of preparation dose: the concrete proportioning of decoction: Cortex Phellodendri 22 grams, Caulis Spatholobi 88 grams, Herba Artemisiae Scopariae 16.5 grams, the Rhizoma Atractylodis Macrocephalae 22 grams, the Radix Astragali 22 grams, Herba Menthae 16.5 grams, Radix Scrophulariae 22 grams, Herba Taraxaci 33 grams, Haematitum 33 grams.
The concrete proportioning of pill: Radix Salviae Miltiorrhizae 110 grams, Flos Tulipae Gesnerianae 110 grams, Ephemerantha lonchophylla (Hook. F) Hunt et Sum-merh. [Ephemerantha fimbrate (Bl.) Hunt et Summerh. 110 grams, Radix Trichosanthis 110 grams, the Radix Astragali 110 grams, Radix Polygoni Multiflori 110 grams, Alumen preparata 110 grams, Natrii Sulfas 55 grams.
The efficacy analysis of this scheme, administration time are 1~2 course of treatment.
Patient's type Recovery from illness Significantly Effectively Invalid
Patients with mild 45 examples 35 8 1 1
Moderate patient's 40 examples 35 3 1 1
Severe patient 15 examples 10 3 1 1
Three, the scheme of the third preparation dose: the concrete proportioning of decoction: Cortex Phellodendri 18 grams, Caulis Spatholobi 72 grams, Herba Artemisiae Scopariae 13.5 grams, the Rhizoma Atractylodis Macrocephalae 18 grams, the Radix Astragali 18 grams, Herba Menthae 13.5 grams, Radix Scrophulariae 18 grams, Herba Taraxaci 27 grams, Haematitum 27 grams.
The concrete proportioning of pill: Radix Salviae Miltiorrhizae 90 grams, Flos Tulipae Gesnerianae 90 grams, Ephemerantha lonchophylla (Hook. F) Hunt et Sum-merh. [Ephemerantha fimbrate (Bl.) Hunt et Summerh. 90 grams, Radix Trichosanthis 90 grams, the Radix Astragali 90 grams, Radix Polygoni Multiflori 90 grams, Alumen preparata 90 grams, Natrii Sulfas 45 grams.
The efficacy analysis of this scheme, administration time are 1~2 course of treatment.
Patient's type Recovery from illness Significantly Effectively Invalid
Patients with mild 50 examples 40 8 1 1
Moderate patient's 40 examples 35 3 1 1
Severe patient 10 examples 6 1 1 2
By Drug therapy chronic aplastic anemia disease of the present invention, received satisfied curative effect.The symptom of this disease is a lot, and this clinical experiment is divided into " slightly ", " moderate " and " seriously " several types according to clinical characters, and this clinical experiment is to carry out jointly at general hospital and special outpatient clinic.
Before this group case treatment, during most of patients was carried out, the treatment of doctor trained in Western medicine mode, but all do not obtain curative effect preferably, especially Western medicine is for oral administration, and side effect is bigger, and human body is caused very major injury.In the process of taking Chinese medicine medicine of the present invention, must not take Western medicine and use injection, or other treats this sick medicine.
The present invention treats the Chinese medicine tonifying liver spleen of chronic aplastic anemia, the nourishing kidney stomach reinforcing, and blood circulation promoting and enriching, qi and blood tonifying, fast lifting platelet, hemoglobin and leukocytic quantity, without any side effects, evident in efficacy, its cure rate reaches 95%.

Claims (3)

1. Chinese medicine for the treatment of chronic aplastic anemia, concrete proportioning feature of the present invention is: the concrete proportioning of decoction: Cortex Phellodendri 20 grams, Caulis Spatholobi 80 grams, Herba Artemisiae Scopariae 15 grams, the Rhizoma Atractylodis Macrocephalae 20 grams, the Radix Astragali 20 grams, Herba Menthae 15 grams, Radix Scrophulariae 20 grams, Herba Taraxaci 30 grams, Haematitum 30 grams; The concrete proportioning of pill: Radix Salviae Miltiorrhizae 100 gram, Flos Tulipae Gesnerianae 100 grams, Ephemerantha lonchophylla (Hook. F) Hunt et Sum-merh. [Ephemerantha fimbrate (Bl.) Hunt et Summerh. 100 grams, Radix Trichosanthis 100 grams, the Radix Astragali 100 grams, Radix Polygoni Multiflori 100 grams, Alumen preparata 100 grams, Natrii Sulfas 50 grams, the degree of accuracy of the dose of this Chinese medicine be each medicine ± 10%.
2. a kind of Chinese medicine for the treatment of chronic aplastic anemia according to claim 1, it is characterized in that: the preparing process of decoction is to fry standby in order to little fire the Rhizoma Atractylodis Macrocephalae earlier, the Rhizoma Atractylodis Macrocephalae and Cortex Phellodendri, Caulis Spatholobi, Herba Artemisiae Scopariae, the Radix Astragali, Herba Menthae, Radix Scrophulariae, Herba Taraxaci, Haematitum after will frying then are mixed into pot, slowly endure with clear water slow fire, treat that decoction is fried in shallow oil and to put into Herba Menthae after ripe, after 3 minutes, removing slag takes concoction, and treats to take behind the room temperature.
3. a kind of Chinese medicine for the treatment of chronic aplastic anemia according to claim 1, it is characterized in that: the preparing process of pill is earlier Radix Salviae Miltiorrhizae to be gone into pot, spray is fried dried standby after drinking, Radix Salviae Miltiorrhizae is 10: 1 with the amount ratio of Chinese liquor, the Radix Salviae Miltiorrhizae of frying after doing is put into sieve with Flos Tulipae Gesnerianae, Ephemerantha lonchophylla (Hook. F) Hunt et Sum-merh. [Ephemerantha fimbrate (Bl.) Hunt et Summerh., Radix Trichosanthis, the Radix Astragali, Radix Polygoni Multiflori, Alumen preparata, Natrii Sulfas, dash, pull the back oven dry out with cool matter clear water sieve, after grinding to form fine powder, machine is made pill and can be prepared to take.
CN 201010291059 2010-09-21 2010-09-21 Traditional Chinese medicine for treating chronic aplastic anemia Pending CN101953943A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103751607A (en) * 2014-01-11 2014-04-30 姜丽莎 Traditional Chinese medicine composition for the treatment of aplastic anemia
CN105770829A (en) * 2016-04-22 2016-07-20 宋桂侠 Traditional Chinese medicine for treating chronic renal anemia

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1137393A (en) * 1995-06-08 1996-12-11 孟涛 Yisuishengxue Chinese medicine preparation for tonifying marrow and promoting generation of blood
CN1785279A (en) * 2005-11-16 2006-06-14 广州陈李济药厂 Blood supplementing iron supplementing medicineal preparation and its preparation method
CN1840006A (en) * 2006-01-26 2006-10-04 周伟 Medicine for treating aplastic anemia
CN101491638A (en) * 2008-11-27 2009-07-29 北京宏泰康达医药科技有限公司 Traditional Chinese medicine composition for treating iron-deficiency anemia
CN101537060A (en) * 2009-04-29 2009-09-23 常俊平 Medicine for treating AIDS
CN101618132A (en) * 2008-07-01 2010-01-06 北京中科仁和科技有限公司 Chinese medicinal herb for treating aplastic anemia

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1137393A (en) * 1995-06-08 1996-12-11 孟涛 Yisuishengxue Chinese medicine preparation for tonifying marrow and promoting generation of blood
CN1785279A (en) * 2005-11-16 2006-06-14 广州陈李济药厂 Blood supplementing iron supplementing medicineal preparation and its preparation method
CN1840006A (en) * 2006-01-26 2006-10-04 周伟 Medicine for treating aplastic anemia
CN101618132A (en) * 2008-07-01 2010-01-06 北京中科仁和科技有限公司 Chinese medicinal herb for treating aplastic anemia
CN101491638A (en) * 2008-11-27 2009-07-29 北京宏泰康达医药科技有限公司 Traditional Chinese medicine composition for treating iron-deficiency anemia
CN101537060A (en) * 2009-04-29 2009-09-23 常俊平 Medicine for treating AIDS

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
《河北农业科技》 20051231 刘建平 新修梯田谷子施用黑矾增产效果明显 , 第2期 2 *
《补髓生血颗粒对慢性再生障碍性贫血患者相关粘附分子及细胞因子的影响》 20060830 徐萍等 补髓生血颗粒对慢性再生障碍性贫血患者相关粘附分子及细胞因子的影响 , 2 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103751607A (en) * 2014-01-11 2014-04-30 姜丽莎 Traditional Chinese medicine composition for the treatment of aplastic anemia
CN105770829A (en) * 2016-04-22 2016-07-20 宋桂侠 Traditional Chinese medicine for treating chronic renal anemia

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