CN104383211A - Traditional Chinese medicine clysis fluid for treating chronic renal insufficiency and yang deficiency-induced cold of diabetic nephropathy - Google Patents

Traditional Chinese medicine clysis fluid for treating chronic renal insufficiency and yang deficiency-induced cold of diabetic nephropathy Download PDF

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Publication number
CN104383211A
CN104383211A CN201410733165.XA CN201410733165A CN104383211A CN 104383211 A CN104383211 A CN 104383211A CN 201410733165 A CN201410733165 A CN 201410733165A CN 104383211 A CN104383211 A CN 104383211A
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radix
rhizoma
chinese medicine
cold
medicine
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赵德语
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    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

Abstract

The invention provides a traditional Chinese medicine clysis fluid for treating chronic renal insufficiency and yang deficiency-induced cold of diabetic nephropathy. The traditional Chinese medicine clysis fluid is prepared from the following Chinese herbs: 100g of prepared rhubarb, 100g of dragon's bone, 100g of oyster, 75g of dandelion, 50g of processed radix aconiti lateralis, 50g of cinnamon, 50g of cassia twig, 50g of szechuan lovage rhizome, 50g of safflower, 50g of poria cocos, 50g of agaric, 50g of rose, 50g of hawthorn, 50g of notoginseng powder, 50g of hairyvein agrimonia herband bud, 50g of corydalis tuber, 50g of peach kernel, 50g of root of bidentate achyranthes, suberect spatholobus stem, 50g of dragon's blood, 25g of frankincense, 25g of myrrh, 50g of root of doubleteeth pubescent angelica, 50g of incised notopterygium, 50g of Chinese rose flower, 50g of India mustard seed, 50g of amber powder, 50g of yam rhizome, 50g of thinleaf milkwort root-bark, 50g of silktree albizzia bark, 50g of gecko, 100g of Chinese yam, 75g of manyprickle acanthopanax root, 50g of medicinal Indian mulberry, 50g of walnut kernel, 50g of songaria cynomorium herb, 50g of tuber fleeceflower root, 50g of Chinese angelica, 100g of tortoise shell, 100g of turtle shell, 50g of malaytea scurfpea fruit and 100g of black chicken bone. The traditional Chinese medicine clysis fluid has the effects of activating blood to dissipate stasis, relieving swelling and pain, eliminating cold to stop pain, clearing damp and promoting diuresis and the like, is capable of effectively covering the shortage that the conventional treatment by use of single western medicine is high in side effect and fails in correcting the yang deficiency-induced cold symptom, and is short in course of treatment and low in side effect.

Description

A kind ofly treat diabetic nephropathy chronic renal insufficiency and the cold Chinese medicinal herbs decoction of yang deficiency folder
Technical field
The present invention relates to and be a kind ofly used for the treatment of diabetic nephropathy chronic renal insufficiency and the cold Chinese medicine of yang deficiency folder, specifically a kind ofly treat diabetic nephropathy chronic renal insufficiency and the cold Chinese medicinal herbs decoction of yang deficiency folder.
Background technology
Diabetic nephropathy chronic renal insufficiency is diabetes de-velopment to one of major complications of end-stage disease, this patient merges the complication of multiple cardiovascular system mostly, the finger disease of clinical blood dialysis is subject to strict restriction, curative effect is often not so good as the chronic renal insufficiency that other primary diseases cause, especially diabetic nephropathy chronic renal insufficiency and the cold patient of yang deficiency folder, utilize merely the conventional therapy side effect of doctor trained in Western medicine large, the symptom that yang deficiency folder is cold can not be corrected, curative effect is undesirable, utilize the combination of Chinese and Western medicine effectively can correct the cold symptom of yang deficiency folder, and short treating period, side effect is little.
Summary of the invention
The object of this invention is to provide and a kind ofly treat diabetic nephropathy chronic renal insufficiency and the cold Chinese medicinal herbs decoction of yang deficiency folder.
For achieving the above object, the technical solution used in the present invention is:
Treat diabetic nephropathy chronic renal insufficiency and the cold Chinese medicinal herbs decoction of yang deficiency folder, it is characterized in that: by the raw material of Chinese medicine of following weight proportion, make according to following preparation technology:
Radix Et Rhizoma Rhei 100g, Os Draconis 100g, Concha Ostreae 100g, Herba Taraxaci 75g, Radix Aconiti Lateralis Preparata 50g, Cortex Cinnamomi 50g, Ramulus Cinnamomi 50g, Rhizoma Chuanxiong 50g, Flos Carthami 50g, Poria 50g, Polyporus 50g, Flos Rosae Rugosae 50g, Fructus Crataegi 50g, Radix Notoginseng powder 50g, Herba Agrimoniae 50g, Rhizoma Corydalis 50g, Semen Persicae 50g, Radix Achyranthis Bidentatae 50g, Caulis Spatholobi 50g, Sanguis Draxonis 50g, Olibanum 25g, Myrrha 25g, Radix Angelicae Pubescentis 50g, Rhizoma Et Radix Notopterygii 50g, Flos Rosae Chinensis 50g, Semen Sinapis 50g, Succinum powder 50g, Rhizoma Dioscoreae Septemlobae 50g, Radix Polygalae 50g, Cortex Albiziae 50g, Gecko 50g, Rhizoma Dioscoreae 100g, Radix Et Caulis Acanthopanacis Senticosi 75g, Radix Morindae Officinalis 50g, Semen Juglandis 50g, Herba Cynomorii 50g, Radix Polygoni Multiflori 50g, Radix Angelicae Sinensis 50g, Carapax Et Plastrum Testudinis 100g, Carapax Trionycis 100g, Fructus Psoraleae 50g, Os Gallus Domesticus 100g,
Preparation technology is: above-mentioned Chinese medicine, through cleaning, oven dry, under aseptic, dustless condition, is prepared according to the following steps:
(1) Os Draconis 100g, Concha Ostreae 100g, Carapax Et Plastrum Testudinis 100g, Carapax Trionycis 100g, Os Gallus Domesticus 100g are smashed and be decocted first 20 minutes;
(2) Radix Et Rhizoma Rhei 100g, Herba Taraxaci 75g, Radix Aconiti Lateralis Preparata 50g, Cortex Cinnamomi 50g, Ramulus Cinnamomi 50g, Rhizoma Chuanxiong 50g, Flos Carthami 50g, Poria 50g, Polyporus 50g, Flos Rosae Rugosae 50g, Fructus Crataegi 50g, Herba Agrimoniae 50g, Rhizoma Corydalis 50g, Semen Persicae 50g, Radix Achyranthis Bidentatae 50g, Caulis Spatholobi 50g, Sanguis Draxonis 50g, Olibanum 25g, Myrrha 25g, Radix Angelicae Pubescentis 50g, Rhizoma Et Radix Notopterygii 50g, Flos Rosae Chinensis 50g, Semen Sinapis 50g, Rhizoma Dioscoreae Septemlobae 50g, Radix Polygalae 50g, Cortex Albiziae 50g, Gecko 50g, Rhizoma Dioscoreae 100g, Radix Et Caulis Acanthopanacis Senticosi 75g, Radix Morindae Officinalis 50g, Semen Juglandis 50g, Herba Cynomorii 50g, Radix Polygoni Multiflori 50g, Radix Angelicae Sinensis 50g, Fructus Psoraleae 50g is soaked in half an hour in cold water,
(3) Radix Notoginseng powder 50g, Succinum powder 50g are for subsequent use;
(4) raw material obtained in step (1) and step (2) merging boiled medicine with boiling machine, decocting liquid of filtering out, puts into the raw material blending of step (3) when decocting liquid being concentrated into 2000ml, and plastic packaging is obtained in the plastic bag of 200ml.
Beneficial effect of the present invention:
1. treating both the principal and secondary aspects of a disease the present invention serves recuperating depleted YANG and rescuing the patient from collapse by multi-medicament use in conjunction, cold expelling warming and recuperating the kidney-YANG, blood circulation promoting and blood stasis dispelling, tranquillizing and allaying excitement, and clear away heart-fire relieving restlessness, inducing diuresis to remove edema, gets rid of vivotoxin, the effect such as to build up resistance; Can QI and blood regulating to greatest extent, improve blood circulation, promote and the immune function of adjustment body, transfer the resistance against diseases of human body inherence, the dynamic equilibrium of adjustment body and external environment and inside of human body, improves physical function on the whole, reaches the object of complete treatment disease.
2. side effect is little, good effect.Herbal enema is that a kind of traditional Chinese medicine intestinal dialysis method makes medicinal liquid absorb at colon, internal rectum, directly plays a role, impels toxin to discharge from intestinal, thus reduce serum creatinine, the level of blood urea nitrogen.Especially the patient of diabetic nephropathy chronic renal insufficiency, because diabetes for many years make its gastrointestinal function all have infringement in various degree, gastrointestinal symptom is given prominence to, in addition in renal insufficiency intoxicating element accumulation body, the poisoning symptom that stimulating gastrointestinal causes, making to take medicine becomes a large difficulty.And adopt the method for herbal retention enema, change the approach of administration, solve difficult problem of taking medicine.
Detailed description of the invention
Below in conjunction with specific embodiment, the invention will be further described:
For diabetic nephropathy chronic renal insufficiency and the cold treatment of yang deficiency folder, at control blood glucose blood pressure, infection control, alleviate azotemia, correction water-electrolyte balance lack of proper care, lie up, low salt diet suit the medicine to the illness and supporting treatment basis on, add and can play recuperating depleted YANG and rescuing the patient from collapse with multiple, cold expelling warming and recuperating the kidney-YANG, blood circulation promoting and blood stasis dispelling, tranquillizing and allaying excitement, clear away heart-fire relieving restlessness, the medicine of building up resistance.QI and blood regulating to greatest extent, improves blood circulation, promotes and adjust the immune function of body, transfer the resistance against diseases of human body inherence, the balance of adjustment body and external environment, and regulate the dynamic equilibrium of human body, improve physical function on the whole, reach dehumidifying YANG invigorating, improve the object of renal function.
Embodiment
The present invention is a kind of treats diabetic nephropathy chronic renal insufficiency and the cold Chinese medicinal herbs decoction of yang deficiency folder, is made up of following raw material of Chinese medicine:
Radix Et Rhizoma Rhei 100g, Os Draconis 100g, Concha Ostreae 100g, Herba Taraxaci 75g, Radix Aconiti Lateralis Preparata 50g, Cortex Cinnamomi 50g, Ramulus Cinnamomi 50g, Rhizoma Chuanxiong 50g, Flos Carthami 50g, Poria 50g, Polyporus 50g, Flos Rosae Rugosae 50g, Fructus Crataegi 50g, Radix Notoginseng powder 50g, Herba Agrimoniae 50g, Rhizoma Corydalis 50g, Semen Persicae 50g, Radix Cyathulae 50g, Caulis Spatholobi 50g, Sanguis Draxonis 50g, Olibanum 25g, Myrrha 25g, Radix Angelicae Pubescentis 50g, Rhizoma Et Radix Notopterygii 50g, Flos Rosae Chinensis 50g, Semen Sinapis 50g, Succinum powder 50g, Rhizoma Dioscoreae Septemlobae 50g, Radix Polygalae 50g, Cortex Albiziae 50g, Gecko 50g, Rhizoma Dioscoreae 100g, Radix Et Caulis Acanthopanacis Senticosi 75g, Radix Morindae Officinalis 50g, Semen Juglandis 50 g, Herba Cynomorii 50g, Radix Polygoni Multiflori 50g, Radix Angelicae Sinensis 50g, Carapax Et Plastrum Testudinis 100g, Carapax Trionycis 100g, Fructus Psoraleae 50g, Os Gallus Domesticus 100g.
Preparation method:
The present invention adopts first-class natural Chinese medicines through cleaning, and the techniques such as oven dry are prepared according to following steps:
(1) Os Draconis 100g, Concha Ostreae 100g, Carapax Et Plastrum Testudinis 100g, Carapax Trionycis 100g, Os Gallus Domesticus 100g are smashed and be decocted first 20 minutes;
(2) Radix Et Rhizoma Rhei 100g, Herba Taraxaci 75g, Radix Aconiti Lateralis Preparata 50g, Cortex Cinnamomi 50g, Ramulus Cinnamomi 50g, Rhizoma Chuanxiong 50g, Flos Carthami 50g, Poria 50g, Polyporus 50g, Flos Rosae Rugosae 50g, Fructus Crataegi 50g, Herba Agrimoniae 50g, Rhizoma Corydalis 50g, Semen Persicae 50g, Radix Achyranthis Bidentatae 50g, Caulis Spatholobi 50g, Sanguis Draxonis 50g, Olibanum 25g, Myrrha 25g, Radix Angelicae Pubescentis 50g, Rhizoma Et Radix Notopterygii 50g, Flos Rosae Chinensis 50g, Semen Sinapis 50g, Rhizoma Dioscoreae Septemlobae 50g, Radix Polygalae 50g, Cortex Albiziae 50g, Gecko 50g, Rhizoma Dioscoreae 100g, Radix Et Caulis Acanthopanacis Senticosi 75g, Radix Morindae Officinalis 50g, Semen Juglandis 50 g, Herba Cynomorii 50g, Radix Polygoni Multiflori 50g, Radix Angelicae Sinensis 50g, Fructus Psoraleae 50g is soaked in half an hour in cold water,
(3) Radix Notoginseng powder 50g, Succinum powder 50g are for subsequent use;
(4) raw material obtained in step (1) and step (2) merging boiled medicine with boiling machine, decocting liquid of filtering out, put into the raw material blending that step (3) is obtained when decocting liquid being concentrated into 2000ml, plastic packaging is for subsequent use in the plastic bag of 200ml.
Using method: the used time gets reserve liquid 1 bag, is put in hot water heating to 39-41 DEG C of coloclysis, retains 40 minutes after coloclysis, and every day respectively once, 20 days is a course for the treatment of sooner or later.
Pharmacology analysis of the present invention:
In raw material of the present invention: 1. Semen Persicae, Radix Cyathulae, Rhizoma Chuanxiong, Fructus Crataegi, Flos Carthami, Flos Rosae Rugosae, Radix Notoginseng powder-blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain; 2. Sanguis Draxonis, Olibanum, Myrrha-promoting blood circulation and stopping pain; 3. Radix Angelicae Pubescentis, Rhizoma Et Radix Notopterygii-easing joint movement, removing dampness to relieve pain; 4. Radix Aconiti Lateralis Preparata, Cortex Cinnamomi, Ramulus Cinnamomi-benefit fire is supporing yang, dispersing cold for relieving pain; 5. Radix Morindae Officinalis, Semen Juglandis, Herba Cynomorii-the kidney invigorating, supporing yang; 6. Caulis Spatholobi, Radix Polygoni Multiflori, Radix Angelicae Sinensis-blood circulation promoting and enriching; 7. Os Draconis, Concha Ostreae-tranquillizing the mind by relieving convulsion, suppressing the hyperactive liver and subsiding YANG, restrains astringent or styptic treatment for spontaneous sweating; 8. Carapax Et Plastrum Testudinis, Carapax Trionycis, Os Gallus Domesticus-nourishing YIN for benefiting the kidney; 9. Fructus Psoraleae, Gecko, Rhizoma Dioscoreae, Radix Et Caulis Acanthopanacis Senticosi-reinforcing spleen and kidney; 10 Poria, Polyporus, succinum, Rhizoma Dioscoreae Septemlobae-promoting diuresis to eliminate damp pathogen, mind tranquilizing and the heart calming; 11 Semen Sinapiss, Rhizoma Corydalis, Flos Rosae Chinensis-promoting blood circulation to remove obstruction in the collateral, promoting the circulation of QI pain relieving, 12 Radix Polygalaes, Cortex Albiziae-mind tranquilizing and the heart calming, reducing swelling and alleviating pain; 13 Herba Agrimoniaes, Herba Taraxaci, Radix Et Rhizoma Rhei-removing toxic substances and promoting subsidence of swelling, blood circulation promoting and blood stasis dispelling.
1. blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain: the active factors in medicine Semen Persicae, Radix Cyathulae, Rhizoma Chuanxiong, Fructus Crataegi, Flos Carthami, Flos Rosae Rugosae, Radix Notoginseng powder can play blood circulation promoting and blood stasis dispelling rapidly, the effect of reducing swelling and alleviating pain.These five kinds of medicines also have good sterilization, antiviral function; Simultaneously antithrombus formation, promoting blood flow, promotes the metabolism of body, thus corrects the abnormal of BUN, the CR brought due to renal insufficiency.
2. promoting blood circulation and stopping pain: the active factors in medicine Sanguis Draxonis, Olibanum, Myrrha can play rapidly the effect of invigorating blood circulation, these two kinds of medicines also have multiple antibiotics, contained resin, natural gum, volatile oil have stronger analgesic activity, can effectively alleviate because the cold headache caused of yang deficiency folder is uncomfortable.
3. easing joint movement, reducing swelling and alleviating pain: the Radix Angelicae Pubescentis in medicine, Rhizoma Et Radix Notopterygii all have good heat-clearing and toxic substances removing, the effect of reducing swelling and alleviating pain, division and the growth of neurogliocyte can be promoted, by the endocrine function that affects the nerves, and then regulate the physiological and pathological of body movable, to reach the effect of detumescence, easing joint movement.
4. mend fire supporing yang, dispersing cold for relieving pain: the Radix Aconiti Lateralis Preparata in medicine, Cortex Cinnamomi, Ramulus Cinnamomi effectively can correct yang deficiency, remove the cold-damp of health, alkaloid wherein in Radix Aconiti Lateralis Preparata, coumarin in Cortex Cinnamomi, cinnamic alcohol, cinnamic acid and cinnamic aldehyde, the cinnamic aldehyde in Ramulus Cinnamomi, ketone, the combined effect of alkene constituents, can press from both sides the cold arthralgia malaise symptoms caused except because of yang deficiency by trivial solution.
5. the kidney invigorating, supporing yang: the Radix Morindae Officinalis in medicine, Semen Juglandis, Herba Cynomorii have good the kidney invigorating, supporing yang effect, the composition such as reducing sugar, glycosides, aminoacid, flavone wherein in Radix Morindae Officinalis, Herba Cynomorii can warming the kidney to activate YANG, reinforcing YIN-essence controlling nocturnal emission with astringent drugs, dispelling cold and removing dampness; Semen Juglandis has defying age, the effect of harmful free radicals in purged body.
6. blood circulation promoting and enriching: the Caulis Spatholobi in medicine, Radix Polygoni Multiflori, Radix Angelicae Sinensis play the effect of blood circulation promoting and enriching jointly, and Caulis Spatholobi also has anticoagulant, reduce blood pressure, the effects such as arrhythmia; The compositions such as the emodin in Radix Polygoni Multiflori, chrysophanol, chrysophanic acid can play benefiting essence-blood, strengthening the tendons and bones, the anti-ageing effect of waiting for a long time; The compositions such as the reducing sugar in Radix Angelicae Sinensis, glycosides, aminoacid, flavone have enriches blood, immunity moderation, promotes the effects such as metabolism, can also increase heart blood supply, and reduce myocardial oxygen consumption, Radix Angelicae Sinensis volatile oil has the effects such as calmness, hypnosis, analgesia, anesthesia; Three medicines share and jointly improve physical function, repair impaired kidney cell.
7. tranquillizing the mind by relieving convulsion, suppressing the hyperactive liver and subsiding YANG, restrains astringent or styptic treatment for spontaneous sweating: the Os Draconis in medicine, Concha Ostreae play tranquillizing the mind by relieving convulsion jointly, suppressing the hyperactive liver and subsiding YANG, restrains astringent or styptic treatment for spontaneous sweating effect, effectively can improve patient's prolonged illness insomnia, yang deficiency, the symptoms such as dysphoria.
8. nourishing YIN for benefiting the kidney: the Carapax Et Plastrum Testudinis in medicine, Carapax Trionycis, Os Gallus Domesticus can nourishing kidney yins, effectively treatment patient soreness of the waist and knees, the effect of muscles and bones not key; Containing several amino acids and trace element in Os Gallus Domesticus, there is strengthening by means of tonics, slow down aging, antimutagenic, the effects such as enhancing non-specific immunity.
9. reinforcing spleen and kidney: the Fructus Psoraleae in medicine, Gecko, Rhizoma Dioscoreae, Radix Et Caulis Acanthopanacis Senticosi play reinforcing spleen and kidney jointly, and kidney tonifying is prolonged life, anti-aging effects.Fructus Psoraleae can increase blood supply of cardiac muscle containing the composition such as Coumarins, flavonoid, monoterpene phenols and volatile oil, soap formula, polysaccharide, lipoid and increase cardiac muscle nutritional blood flow, and also have the effects such as leukocyte increasing, four medicines share and obviously can improve renal function.
10. promoting diuresis to eliminate damp pathogen, mind tranquilizing and the heart calming: the Poria in medicine, Polyporus, succinum, Rhizoma Dioscoreae Septemlobae energy promoting diuresis to eliminate damp pathogen, can eliminate the water-sodium retention that renal insufficiency causes, mind tranquilizing and the heart calming effect; Can effectively solve because the vexed insomnia of patient caused accumulated by toxin.Siberian cocklebur polysaccharide contained by Poria, Polyporus also has antitumor, strengthens the function of immunity, effectively can strengthen the body constitution of patient.
11. promoting blood circulation to remove obstruction in the collateral, promoting the circulation of QI pain relieving: the Semen Sinapis in medicine, Rhizoma Corydalis, Flos Rosae Chinensis can play promoting blood circulation to restore menstrual flow network, cold expelling is tied, the effect of promoting the circulation of QI pain relieving, and wherein Rhizoma Corydalis also has analgesia, calmness, hypnosis, antithrombotic, the effect such as resist myocardial ischemia.
12. mind tranquilizing and the heart calming, reducing swelling and alleviating pain: the Radix Polygalae in medicine, Cortex Albiziae play mind tranquilizing and the heart calming, the effect of reducing swelling and alleviating pain, the Saponin ketone contained in Radix Polygalae. acid alcohols etc. have edema, diuresis, the effects such as mutation is anticancer, tranquillizing and allaying excitement.The lignan's glucoside, acid, ester etc. that contain in Cortex Albiziae can tranquilizing the mind, control melancholy insomnia, the effects such as promoting blood circulation to remove blood stasis.Two medicines share the metabolism that effectively can improve renal function, alleviate edema, tranquilizing the mind, build up resistance.
13. removing toxic substances and promoting subsidence of swelling, blood circulation promoting and blood stasis dispelling: in medicine, Herba Agrimoniae, Herba Taraxaci, Radix Et Rhizoma Rhei have removing toxic substances and promoting subsidence of swelling, the effect of blood circulation promoting and blood stasis dispelling; Containing chemical compositions such as phenol, ester, flavone, tannin, glucosides, organic acid, volatile oil, triterpene saponin in Chinese medicine Herba Agrimoniae, Herba Taraxaci, there is many-sided pharmacological actions such as antitumor, blood sugar lowering, antalgic and inflammation relieving, blood pressure lowering, malaria, arrhythmia, enhancing immunity, the effective ingredient of Radix Et Rhizoma Rhei has diuresis, antimicrobial antiphlogistic, antipyretic, immunity moderation epidemic disease power, improves the effects such as renal function.
Pharmacodynamics statistics of the present invention:
1. general clinical data: that chooses diabetes section of being in hospital the same period meets diabetic nephropathy chronic renal insufficiency and cold patient 164 example of yang deficiency folder, is divided into two groups at random; Treatment group 82 example, man 44 example, female 38 example; Age 21.47-79.42 year, average 59.31 years old; Matched group 82 example, man 47 example, female 36 example, age 23.71-83.34 year, average 57.72 years old; The state of an illness is the shortest 20 days, the longest 5.5 years; These two random group patients compare in sex, age, nutriture etc., no significant difference (P > 0.05).
2. using method: treatment group: give reserve liquid 1 bag on western medicine routine treatment basis, be put in hot water heating to 39-41 DEG C, coloclysis; Matched group: adopt western medicine routine treatment, mainly comprise: correct acid base imbalance, supplement calcium preparation, infection, oral Coated Aldehyde Oxystarch etc.Two groups was all 1 course for the treatment of with 20 days.
3. evaluation index: diagnostic criteria is worked out according to " nephrology " CRF diagnostic criteria, and its Main Diagnosis main points are: 1. have the chronic kidney disease history of diabetic nephropathy; 2. clinical symptoms that is weak, the CRF such as inappetence and anemia is had; 3. lab testing: blood biochemistry creatinine (Cr), blood urea nitrogen (BUN) raise, Water-Electrolyte and acid base imbalance, high calcium hyperphosphatemia; 4. the two kidney of B-ultrasonic renal display reduces, and cortex is thinning.Azotemia phase patient is selected to be the object of observation, get rid of acute renal insufficiency, chronic hepatopathy and Patients With Various Thyroid Disorders, respectively at observe the curative effect after one, two courses for the treatment of of treatment: measure serum creatinine (Scr), endogenous creatinine clearance rate (Ccr), blood urea nitrogen (BUN)." new Chinese medicine guideline of clinical investigations " that efficacy determination is formulated with reference to Ministry of Public Health.Effective: clinical symptom relief or disappearance, endogenous creatinine clearance rate (Ccr) increases >=30%, and serum creatinine (Scr) reduces >=30%; Effective: clinical symptom relief or disappearance, Ccr increases by >=20%, Scr and reduces >=20%; Invalid: not reach above-mentioned standard person.
4. statistical method application SPSS13.0 statistical analysis software carries out data analysis, and between two groups, comparitive study adopts x2 inspection, and p ﹤ 0.05 has statistical significance for difference.
 
Two groups of comparitive study after the course for the treatment of of table 1
Note: compare x2=11.30 p<0.05 there were significant differences with matched group
Two groups of comparitive study after two courses for the treatment of of table 2
Note: compare x2=22.13 p<0.05 there were significant differences with matched group
5. result: treatment group patient is through first, and after second course for the treatment of, total effective rate is apparently higher than matched group, and difference has statistical significance (P < 0.05).
Unique distinction of the present invention shows: herbal enema serves blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, the kidney invigorating, mend fire supporing yang, dispersing cold for relieving pain, tranquillizing the mind by relieving convulsion, the effects such as promoting diuresis to eliminate damp pathogen, effectively can make up and utilize merely the conventional therapy side effect of doctor trained in Western medicine large and the shortcoming short treating period can not correcting yang deficiency folder sympotoms caused by cold factors shape, side effect is little.
Embodiment recited above is only be described the preferred embodiment of the present invention; not design of the present invention and protection domain are limited; under the prerequisite not departing from design concept of the present invention; the various modification that in this area, common engineers and technicians make technical scheme of the present invention and improvement, all should fall into protection scope of the present invention.

Claims (1)

1. treat diabetic nephropathy chronic renal insufficiency and the cold Chinese medicinal herbs decoction of yang deficiency folder, it is characterized in that: by the raw material of Chinese medicine of following weight proportion, make according to following preparation technology:
Radix Et Rhizoma Rhei 100g, Os Draconis 100g, Concha Ostreae 100g, Herba Taraxaci 75g, Radix Aconiti Lateralis Preparata 50g, Cortex Cinnamomi 50g, Ramulus Cinnamomi 50g, Rhizoma Chuanxiong 50g, Flos Carthami 50g, Poria 50g, Polyporus 50g, Flos Rosae Rugosae 50g, Fructus Crataegi 50g, Radix Notoginseng powder 50g, Herba Agrimoniae 50g, Rhizoma Corydalis 50g, Semen Persicae 50g, Radix Achyranthis Bidentatae 50g, Caulis Spatholobi 50g, Sanguis Draxonis 50g, Olibanum 25g, Myrrha 25g, Radix Angelicae Pubescentis 50g, Rhizoma Et Radix Notopterygii 50g, Flos Rosae Chinensis 50g, Semen Sinapis 50g, Succinum powder 50g, Rhizoma Dioscoreae Septemlobae 50g, Radix Polygalae 50g, Cortex Albiziae 50g, Gecko 50g, Rhizoma Dioscoreae 100g, Radix Et Caulis Acanthopanacis Senticosi 75g, Radix Morindae Officinalis 50g, Semen Juglandis 50g, Herba Cynomorii 50g, Radix Polygoni Multiflori 50g, Radix Angelicae Sinensis 50g, Carapax Et Plastrum Testudinis 100g, Carapax Trionycis 100g, Fructus Psoraleae 50g, Os Gallus Domesticus 100g,
Preparation technology is: above-mentioned Chinese medicine, through cleaning, oven dry, under aseptic, dustless condition, is prepared according to the following steps:
(1) Os Draconis 100g, Concha Ostreae 100g, Carapax Et Plastrum Testudinis 100g, Carapax Trionycis 100g, Os Gallus Domesticus 100g are smashed and be decocted first 20 minutes;
(2) Radix Et Rhizoma Rhei 100g, Herba Taraxaci 75g, Radix Aconiti Lateralis Preparata 50g, Cortex Cinnamomi 50g, Ramulus Cinnamomi 50g, Rhizoma Chuanxiong 50g, Flos Carthami 50g, Poria 50g, Polyporus 50g, Flos Rosae Rugosae 50g, Fructus Crataegi 50g, Herba Agrimoniae 50g, Rhizoma Corydalis 50g, Semen Persicae 50g, Radix Achyranthis Bidentatae 50g, Caulis Spatholobi 50g, Sanguis Draxonis 50g, Olibanum 25g, Myrrha 25g, Radix Angelicae Pubescentis 50g, Rhizoma Et Radix Notopterygii 50g, Flos Rosae Chinensis 50g, Semen Sinapis 50g, Rhizoma Dioscoreae Septemlobae 50g, Radix Polygalae 50g, Cortex Albiziae 50g, Gecko 50g, Rhizoma Dioscoreae 100g, Radix Et Caulis Acanthopanacis Senticosi 75g, Radix Morindae Officinalis 50g, Semen Juglandis 50g, Herba Cynomorii 50g, Radix Polygoni Multiflori 50g, Radix Angelicae Sinensis 50g, Fructus Psoraleae 50g is soaked in half an hour in cold water,
(3) Radix Notoginseng powder 50g, Succinum powder 50g are for subsequent use;
(4) raw material obtained in step (1) and step (2) merging boiled medicine with boiling machine, decocting liquid of filtering out, puts into the raw material blending of step (3) when decocting liquid being concentrated into 2000ml, and plastic packaging is obtained in the plastic bag of 200ml.
CN201410733165.XA 2014-12-07 2014-12-07 Traditional Chinese medicine clysis fluid for treating chronic renal insufficiency and yang deficiency-induced cold of diabetic nephropathy Pending CN104383211A (en)

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CN109999085A (en) * 2019-04-09 2019-07-12 新疆医科大学第四附属医院 A kind of Chinese herb medicine for treating chronic kidney disease

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Application publication date: 20150304