CN1057230C

CN1057230C - Traditional Chinese medicine capsule for treating thrombophlebitis

Info

Publication number: CN1057230C
Application number: CN98119889A
Authority: CN
Inventors: 李正武
Original assignee: Individual
Current assignee: Individual
Priority date: 1998-09-28
Filing date: 1998-09-28
Publication date: 2000-10-11
Anticipated expiration: 2018-09-28
Also published as: CN1212885A

Abstract

The present invention relates to a traditional Chinese medicine capsule for treating thrombophlebitis. The present invention adopts traditional Chinese medicines, such as ants, angelica, spatholobus stems, achyranthes roots, phellodendron bark, astragalus roots, white atractylodes rhizomes, red sage roots, etc. as raw materials, the traditional Chinese medicines are manufactured into medicinal powder through the technological processes of pulverization, immersion, decoction, filtration, concentration, ethanol extraction, mixing, porphyrization, etc. according to the properties of the traditional Chinese medicines, and then, the medicinal powder is encapsulated. The present invention has unique prescription and high cure rate.

Description

The Chinese medicinal capsule of treatment thrombophlebitis

The present invention relates to a kind of Chinese medicine preparation for the treatment of peripheral vascular disease.

Thrombophlebitis is that the vessel wall inflammation secondary thrombus forms.The formation reason of thrombosis is also unclear fully at present, it is generally acknowledged wall of vein damage, blood flow is slow and blood coagulation to increase be the key factor that forms.The western medical treatment thrombophlebitis generally adopts operative therapy: vein ligatures, vein excises and thrombosis is extractd.According to clinical practice, the state of an illness still can recur after many patients performed the operation, and the repeatedly operation that has is not cured yet.Operative therapy not only has certain misery to the patient, and cure rate is lower.The Western medicine oral dicoumarols of injecting heparin commonly used etc., price is more expensive, and side effect is arranged.For the traditional Chinese medical science, Chinese medicine preparation was many in the past dehumidifies to controlling to invigorate blood circulation, and has ignored the treatment of detoxifcation, removing heat from blood, and therefore used pharmaceutical treatment effect is relatively poor.

The object of the present invention is to provide a kind of pure Chinese medicine capsule for the treatment of thrombophlebitis, not only have the very significant advantage of therapeutic effect, and taking convenience.

Solution of the present invention is based on the treatment theory of motherland's medical science to peripheral angiopathy, in conjunction with clinical practice, from motherland's Chinese medicine treasure-house, filter out invigorate blood circulation, removing heat from blood, the detoxifcation, the dehumidifying, promoting the circulation of blood is enriched blood, the pure Chinese medicine of Shujin, collateral dredging by the theory of Chinese medical science prescription, skims the cream off milk, make it have blood vessel dilating, thrombus, accelerate blood circulation, change local blood supply state, improve body immunity, setting upright gets rid of evils is fully recovered thrombophlebitis.

The proportioning raw materials of Chinese medicinal capsule of the present invention (with weight portion):

Formica fusca 3-10 Radix Glycyrrhizae 1-10 Semen Persicae 3-9 Rhizoma Curcumae 2-9

Radix Salviae Miltiorrhizae 1-10 Radix Clematidis 1-6 Radix Achyranthis Bidentatae 1-12 Radix Angelicae Sinensis 3-15

Rhizoma Corydalis 2-9 Radix Astragali 1-15 Cortex Phellodendri 1-6 Rhizoma Alismatis 2-10

Herba Artemisiae Scopariae 5-30 Semen Phaseoli 1-6 Radix Stephaniae Tetrandrae 2-9 Herba Eupatorii 6-10

Rhizoma Atractylodis Macrocephalae 1-15 Caulis Spatholobi 5-30 Rhizoma Atractylodis 3-10 Radix Paeoniae Rubra 5-15

Caulis Akebiae 1-5 Flos Lonicerae 1-20 Fructus Amomi Rotundus 1-9

Preferred weight (part) ratio range of preparation Chinese medicinal capsule of the present invention is:

Formica fusca 5-8 Radix Glycyrrhizae 3-8 Semen Persicae 5-7 Rhizoma Curcumae 5-7

Radix Salviae Miltiorrhizae 3-8 Radix Clematidis 3-5 Radix Achyranthis Bidentatae 3-10 Radix Angelicae Sinensis 5-10

Rhizoma Corydalis 5-7 Radix Astragali 3-10 Cortex Phellodendri 3-5 Rhizoma Alismatis 4-8

Herba Artemisiae Scopariae 8-20 Semen Phaseoli 3-5 Radix Stephaniae Tetrandrae 4-7 Herba Eupatorii 7-9

Rhizoma Atractylodis Macrocephalae 4-12 Caulis Spatholobi 7-25 Rhizoma Atractylodis 5-8 Radix Paeoniae Rubra 8-12

Caulis Akebiae 2-4 Flos Lonicerae 4-15 Bai Fructus Amomi Rotundus 1-9

The optimum weight of Chinese medicinal capsule of the present invention (part) ratio range is:

Formica fusca 6 Radix Glycyrrhizaes 5 Semen Persicaes 6 Rhizoma Curcumae 5

Radix Salviae Miltiorrhizae 5 Radix Clematidis 3 Radix Achyranthis Bidentataes 6 Radix Angelicae Sinensis 8

Rhizoma Corydalis 5 Radixs Astragali 8 Cortex Phellodendris 4 Rhizoma Alismatis 6

Herba Artemisiae Scopariae 15 Semen Phaseolis 4 Radixs Stephaniae Tetrandrae 6 Herba Eupatoriis 8

The Rhizoma Atractylodis Macrocephalae 8 Caulis Spatholobis 15 Rhizoma Atractylodis 7 Radix Paeoniae Rubra 10

Caulis Akebiae 3 Flos Loniceraes 10 Fructus Amomi Rotunduss 8

The production method that above-mentioned each component is made Chinese medicinal capsule of the present invention is:

1, Formica fusca is worn into coarse powder, the little stir-fry of all the other medicines, fragmentation;

2, the total amount input is carried jar, and the octuple water logging that adds weight was steeped 6 hours, decocted filtration in 40 minutes, adds six times of water gagings again and decocts 30 minutes after-filtration, merges filtrate twice;

3, filtrate concentrates (contracting to 1ml by the 1g crude drug);

4, adding ethanol makes the alcohol amount of containing reach 60-70% to stir evenly, left standstill 24 hours, cross the leaching supernatant, get ethanol (reaching relative density more than 1.10);

5, get above-mentioned concentrated solution and add an amount of food starch, dry in the shade, porphyrize, cross 120 mesh sieves and make powder;

6, incapsulate with the 0.5g/ grain.

The instructions of taking of Chinese medicinal capsule of the present invention: three times on the one, each 1-3 grain, one hour ante cibum (empty clothes), boiled water send down.

Chinese medicinal capsule of the present invention shows that through clinical use result following advantage is arranged:

1, because described medical material: Formica fusca has antiinflammatory, the analgesic significantly acts on, help to eliminate immune complex in the body, can control the inferior limb stain infections, but Radix Glycyrrhizae heat-clearing and toxic substances removing, relieving spasm to stop pain, but Semen Persicae activating blood and removing stasis, promoting the circulation of QI to relieve pain, but Radix Salviae Miltiorrhizae activating blood and removing stasis, removing heat from blood disappears bitterly, nourishing blood to tranquillize the mind, but Radix Clematidis wind-damp dispelling, the meridian dredging, stopping numbness pain, but Radix Achyranthis Bidentatae activating blood and removing stasis, inducing diuresis for treating stranguria syndrome, conducting blood to flow downwards, but the Radix Angelicae Sinensis blood circulation promoting and enriching, Rhizoma Corydalis can be invigorated blood circulation, circulation of qi promoting relieves the pain, but the Caulis Spatholobi promoting the circulation of blood is enriched blood, relaxing muscles and tendons and activating QI and blood in the collateral, but Radix Astragali tonifying Qi and lifting yang, strengthening superficial resistance to stop perspiration, holder skin ulcer granulation promoting, inducing diuresis to remove edema, but Cortex Phellodendri heat-clearing and toxic substances removing dampness, but Rhizoma Alismatis promoting diuresis to eliminate damp pathogen, expel the heat-evil, but the Flos Lonicerae heat-clearing and toxic substances removing, but Herba Artemisiae Scopariae clearing away heat-damp and promoting diuresis, it is dirty that but the Herba Eupatorii removing dampness is warded off, but Semen Phaseoli eliminating dampness by diuresis heat clearing away, removing toxic substances and promoting pus discharge, the Radix Stephaniae Tetrandrae wind-damp dispelling, inducing diuresis to remove edema, but Rhizoma Atractylodis Macrocephalae QI invigorating, spleen invigorating, dampness, the Fructus Amomi Rotundus removing dampness by means of aromatics, therefore, comprehensively respectively the distinguish the flavor of effect of Chinese medicine of the present invention, make prescription not only have the effect of the dehumidifying of invigorating blood circulation, and detoxifcation is arranged, removing heat from blood is fruit.Phlebitis patient takes the present invention's Chinese medicine preparation, and therapeutic effect is very remarkable.

2, because the present invention be a pure Chinese medicinal preparation, each component meets pharmaceutical control law regulation, thus nontoxic, harmless to human body, have no side effect.

3,, and meet national drug health regulation because the present invention is the Chinese medicinal capsule taking convenience.

The present invention has very significant curative effect through the clinical observation of 102 routine systems to thrombophlebitis, can be found out by following table: to the deep phlebitis cure rate more than 86%, and comprehensive cure rate 95.1%.

Thrombophlebitis therapeutic effect statistical table

The course of treatment		Clinical manifestation (number)		Therapeutic effect (%)
		Clinical manifestation (number)			Superficial phlebitis	Deep phlebitis
		One course of treatment	Effectively		Superficial phlebitis	Deep phlebitis	80	22	100％
Cure	31		Effectively	4	34.3％		80	22	100％
Cure	31		Two courses of treatment	4	34.3％	Cure	34	9	65.7％
Three courses of treatment	Cure little vestige that has	13	Two courses of treatment	6 3	82.6％	Cure	34	9	65.7％
Three courses of treatment	Cure little vestige that has	13	Therapeutic effect	6 3	82.6％	Effectively	100％	100％	100％
Cure	97.5％	86.3％		95.1％		Effectively	100％	100％	100％

Embodiment:

Take by weighing raw material (kilogram) by following proportioning:

Formica fusca 8 Radix Glycyrrhizaes 8 Semen Persicaes 7 Rhizoma Curcumae 7

Radix Salviae Miltiorrhizae 8 Radix Clematidis 5 Radix Achyranthis Bidentataes 10 Radix Angelicae Sinensis 10

Rhizoma Corydalis 7 Radixs Astragali 10 Cortex Phellodendris 5 Rhizoma Alismatis 8

Herba Artemisiae Scopariae 20 Semen Phaseolis 5 Radixs Stephaniae Tetrandrae 7 Herba Eupatoriis 9

The Rhizoma Atractylodis Macrocephalae 12 Caulis Spatholobis 20 Rhizoma Atractylodis 8 Radix Paeoniae Rubra 12

Caulis Akebiae 4 Flos Loniceraes 15 Fructus Amomi Rotunduss 9

Production method is as follows:

(1) Formica fusca is worn into coarse powder, the little stir-fry of all the other medicines, fragmentation; (2) the total amount input is carried jar, and the octuple water logging that adds weight was steeped 6 hours, decocted filtration in 40 minutes, adds six times of water gagings again and decocts 30 minutes after-filtration, merges filtrate twice; (3) filtrate concentrates (contracting to 1ml by the 1g crude drug); (4) adding ethanol makes the alcohol amount of containing reach 60-70% to stir evenly, left standstill 24 hours, cross the leaching supernatant, get ethanol and reach relative density more than 110; (5) get above-mentioned concentrated solution and add an amount of food starch, dry in the shade, porphyrize, cross 120 mesh sieves and make powder; (6) incapsulate with the 0.5g/ grain.

Claims

1, a kind of Chinese medicinal capsule for the treatment of thrombophlebitis is characterized in that the weight proportion of each raw material is:

Formica fusca 3-10 Radix Glycyrrhizae 1-10 Semen Persicae 39 Rhizoma Curcumae 2-9

Caulis Akebiae 1-5 Flos Lonicerae 1-20 Fructus Amomi Rotundus 1-9 wears into coarse powder with Formica fusca, the little stir-fry of all the other medicines, fragmentation; The total amount input is carried jar, and the octuple water logging that adds weight was steeped 6 hours, decocted filtration in 40 minutes, adds six times of water gagings again and decocts 30 minutes after-filtration, merges filtrate twice; It is concentrated to 1ml to contract by the 1g crude drug; Adding ethanol makes the alcohol amount of containing reach 60-70% to stir evenly, left standstill 24 hours, cross the leaching supernatant, get ethanol and reach relative density more than 110: get above-mentioned concentrated solution and add an amount of food starch, dry in the shade, porphyrize, cross 120 mesh sieves and make powder; Incapsulate with the 0.5g/ grain.

2, the Chinese medicinal capsule of treatment thrombophlebitis according to claim 1, wherein the weight proportion of each raw material is:

Radix Salviae Miltiorrhizae 3-8 CHENGLINGXIAN 3-5 Radix Achyranthis Bidentatae 3-10 Radix Angelicae Sinensis 5-10

Caulis Akebiae 2-4 Flos Lonicerae 4-15 Fructus Amomi Rotundus 1-9

3, the Chinese medicinal capsule of treatment thrombophlebitis according to claim 1, wherein the weight proportion of each raw material is:

Formica fusca 6 Radix Glycyrrhizaes 5 Semen Persicaes 6 Rhizoma Curcumae 5

Caulis Akebiae 3 Flos Loniceraes 10 Fructus Amomi Rotunduss 8

4, the manufacture method of the Chinese medicinal capsule of claim 1,2 or 3 described treatment thrombophlebitis is characterized in that technology step poly-ly is:

(1) prepares Chinese crude drug in Formica fusca 3-10, Radix Glycyrrhizae 1-10, Semen Persicae 3-9, Rhizoma Curcumae 2-9, Radix Salviae Miltiorrhizae 1-10, Radix Clematidis 1-6, Radix Achyranthis Bidentatae 1-12, Radix Angelicae Sinensis 3-15, Rhizoma Corydalis 2-9, Radix Astragali 1-15, Cortex Phellodendri 1-6, Rhizoma Alismatis 210, Herba Artemisiae Scopariae 5-30, Semen Phaseoli 1-6, Radix Stephaniae Tetrandrae 2-9, Herba Eupatorii 6-10, Rhizoma Atractylodis Macrocephalae 1-15, Caulis Spatholobi 5-30, Rhizoma Atractylodis 3-10, Radix Paeoniae Rubra 5-15, Caulis Akebiae 1-5, Flos Lonicerae 1-20, Fructus Amomi Rotundus 1-9 ratio;

(2) Formica fusca is worn into coarse powder, the little stir-fry of all the other medicines, fragmentation;

(3) the total amount input is carried jar, and the octuple water logging that adds weight was steeped 6 hours, decocted filtration in 40 minutes, adds six times of water gagings again and decocts 30 minutes after-filtration, merges filtrate twice;

(4) contract to 1ml by the 1g crude drug and concentrate;

(5) adding ethanol makes the alcohol amount of containing reach 60-70% to stir evenly, left standstill 24 hours, cross the leaching supernatant, get ethanol and reach relative density more than 110;

(6) get above-mentioned concentrated solution and add an amount of food starch, dry in the shade, porphyrize, cross 120 mesh sieves and make powder;

(7) incapsulate with the 0.5g/ grain.