CN102949658B - Drug formula for treating hepatitis - Google Patents
Drug formula for treating hepatitis Download PDFInfo
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- CN102949658B CN102949658B CN201110250121.8A CN201110250121A CN102949658B CN 102949658 B CN102949658 B CN 102949658B CN 201110250121 A CN201110250121 A CN 201110250121A CN 102949658 B CN102949658 B CN 102949658B
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- grams
- radix
- treating hepatitis
- rhizoma
- formula
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- 239000003814 drug Substances 0.000 title abstract description 10
- 229940079593 drug Drugs 0.000 title abstract description 6
- 208000006454 hepatitis Diseases 0.000 title abstract 2
- 231100000283 hepatitis Toxicity 0.000 title abstract 2
- 208000002672 hepatitis B Diseases 0.000 claims abstract description 12
- 239000008194 pharmaceutical composition Substances 0.000 claims description 6
- 239000009636 Huang Qi Substances 0.000 claims description 4
- 241000208340 Araliaceae Species 0.000 claims description 3
- 241001550206 Colla Species 0.000 claims description 3
- 241000209020 Cornus Species 0.000 claims description 3
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims description 3
- 235000003140 Panax quinquefolius Nutrition 0.000 claims description 3
- 239000010135 fructus aurantii immaturus Substances 0.000 claims description 3
- 235000008434 ginseng Nutrition 0.000 claims description 3
- 239000000843 powder Substances 0.000 abstract description 2
- 235000008658 Artemisia capillaris Nutrition 0.000 abstract 1
- 241000092668 Artemisia capillaris Species 0.000 abstract 1
- 241000045403 Astragalus propinquus Species 0.000 abstract 1
- 241000132012 Atractylodes Species 0.000 abstract 1
- 244000183685 Citrus aurantium Species 0.000 abstract 1
- 235000007716 Citrus aurantium Nutrition 0.000 abstract 1
- 235000010254 Jasminum officinale Nutrition 0.000 abstract 1
- 240000005385 Jasminum sambac Species 0.000 abstract 1
- 240000001659 Oldenlandia diffusa Species 0.000 abstract 1
- 235000002789 Panax ginseng Nutrition 0.000 abstract 1
- 241000405414 Rehmannia Species 0.000 abstract 1
- 244000153955 Reynoutria sachalinensis Species 0.000 abstract 1
- 235000003202 Reynoutria sachalinensis Nutrition 0.000 abstract 1
- 240000004980 Rheum officinale Species 0.000 abstract 1
- 235000008081 Rheum officinale Nutrition 0.000 abstract 1
- 235000017276 Salvia Nutrition 0.000 abstract 1
- 240000007164 Salvia officinalis Species 0.000 abstract 1
- 240000004534 Scutellaria baicalensis Species 0.000 abstract 1
- 235000017089 Scutellaria baicalensis Nutrition 0.000 abstract 1
- 241000270666 Testudines Species 0.000 abstract 1
- 235000006533 astragalus Nutrition 0.000 abstract 1
- 239000003292 glue Substances 0.000 abstract 1
- 239000006187 pill Substances 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 description 7
- 210000004369 blood Anatomy 0.000 description 5
- 239000008280 blood Substances 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 208000024891 symptom Diseases 0.000 description 4
- 208000004880 Polyuria Diseases 0.000 description 3
- 230000017531 blood circulation Effects 0.000 description 3
- 230000035619 diuresis Effects 0.000 description 3
- 210000004185 liver Anatomy 0.000 description 3
- 210000000952 spleen Anatomy 0.000 description 3
- 206010059193 Acute hepatitis B Diseases 0.000 description 2
- 208000000419 Chronic Hepatitis B Diseases 0.000 description 2
- 230000001154 acute effect Effects 0.000 description 2
- 208000037628 acute hepatitis B virus infection Diseases 0.000 description 2
- 239000002775 capsule Substances 0.000 description 2
- 230000004087 circulation Effects 0.000 description 2
- 210000003494 hepatocyte Anatomy 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 238000005728 strengthening Methods 0.000 description 2
- 206010000077 Abdominal mass Diseases 0.000 description 1
- 101710142246 External core antigen Proteins 0.000 description 1
- 206010023126 Jaundice Diseases 0.000 description 1
- 238000008050 Total Bilirubin Reagent Methods 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 210000004404 adrenal cortex Anatomy 0.000 description 1
- 230000000259 anti-tumor effect Effects 0.000 description 1
- 230000001174 ascending effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 208000019425 cirrhosis of liver Diseases 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000006735 deficit Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 208000020694 gallbladder disease Diseases 0.000 description 1
- 230000002443 hepatoprotective effect Effects 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a drug formula for treating hepatitis. The drug formula is characterized by comprising the following components: 10g of rheum officinale, 15g of radix curcumae, 10g of radix bupleuri, 15g of scutellaria baicalensis, 15g of giant knot weed, 15g of hedyotis diffusa, 20g of capillary artemisia, 30g of turtle shell, 20g of red-rooted salvia root, 20g of bighead atractylodes rhizome, 30g of rhizoma dioscoreae, 15g of immature bitter orange, 15g of red ginseng, 40g of astragalus mongholicus, 30g of root of rehmannia, 10g of deer-horn glue and 15g of jasmine. The medicines are pulverized to make 80-100 meshes of powder according to the weight proportion, and are made to be pills of 10g. The formula is reasonable in preparation, and is mainly used for treating hepatitis B.
Description
Affiliated technical field
The present invention relates to a kind of pharmaceutical composition for the treatment of hepatitis B, comprise the pharmaceutical composition for the treatment of acute and chronic hepatitis B.
Background technology
Hepatitis B is covered by among the scope of motherland's medical science jaundice, and its pathogenesis key is damp and hot heresy, again because the touching difficulty of most patient heals, to the patient, causes all empty disease characteristics of negative and positive of qi and blood; Modern medicine study thinks, along with the progress of the course of disease, hepatitis B will occur that immunologic function is low gradually, appearance toleration, the adrenal cortex function even the had Clinical symptoms of tissue organ function's decay such as fade, and the hepatocyte that even occurs had is cancerated.
Summary of the invention
The object of the present invention is to provide a kind of evident in efficacy pharmaceutical composition that is used for the treatment of acute and chronic hepatitis B.
Plan method for the treatment of of the present invention is: clearing away heat-damp and promoting diuresis, blood circulation promoting and blood stasis dispelling, strengthening spleen, tonifying kidney.
Pharmaceutical composition of the present invention is as follows:
Radix Et Rhizoma Rhei 10 grams, Radix Curcumae 15 grams, Radix Bupleuri 10 grams, Radix Scutellariae 15 grams, Rhizoma Polygoni Cuspidati 15 grams, Hedyotidis Diffusae 15 grams, Herba Artemisiae Scopariae 20 grams, Carapax Trionycis 30 grams, Radix Salviae Miltiorrhizae 20 grams, the Rhizoma Atractylodis Macrocephalae 20 grams, Rhizoma Dioscoreae 30 grams, Fructus Aurantii Immaturus 15 grams, Radix Ginseng Rubra 15 grams, the Radix Astragali 40 grams, the Radix Rehmanniae 30 grams, Colla cornus cervi 10 grams, Fructus Gardeniae 15 grams.
By said medicine according to dosage ratio be ground into 80-100 purpose powder, the Capsules of the 0.5g that packs into, one time 20 oral, 3 times on the one, be a course for the treatment of February, takes 3-5 the course for the treatment of, generally can receive curative effect preferably.
In side: Herba Artemisiae Scopariae, Fructus Gardeniae, Hedyotidis Diffusae clearing away heat-damp and promoting diuresis, diuresis, make damp and hot heresy separate from urine, and wherein, Hedyotidis Diffusae, according to modern study, has antitumor action, can prevent that hepatitis B from cancerating; The Radix Et Rhizoma Rhei bitter cold is joined the Fructus Aurantii Immaturus circulation of qi promoting painful abdominal mass that disappears under rushing down, can make damp and hotly to go out from stool the heresy that liver-gallbladder disease is half exterior and half interior, Radix Bupleuri is joined Radix Scutellariae can make its evil expeling, in addition, Radix Bupleuri has hepatoprotective effect according to modern study, due to stagnant middle Jiao of damp and hot harmony, cause the imbalance of taste ascending or descending movement of vital Qi, suffocating of liver and gall generation obstacle, thereby two sides of body occur have a pain, with Radix Curcumae, Rhizoma Polygoni Cuspidati, Radix Salviae Miltiorrhizae circulation of qi promoting, blood circulation promoting and blood stasis dispelling, thereby the blood circulation state of change liver; The Rhizoma Atractylodis Macrocephalae, Rhizoma Dioscoreae, Radix Ginseng Rubra, the Radix Astragali, the Radix Rehmanniae, Colla cornus cervi, Carapax Trionycis all have the effect of strengthening spleen, tonifying kidney, thereby correct the clinical picture of hepatitis B patient various functions decline, in addition, Radix Rehmanniae YIN nourishing and the production of body fluid promoting, can prevent that activating blood and removing stasis drug from being used of a specified duration, excessively consumes impairment of YIN blood, the Radix Astragali is according to modern medicine study, the effect of free radical resisting is arranged, prevent that hepatocyte from cancerating, Carapax Trionycis can make the liver spleen of enlargement dwindle.
This beneficial effect of the invention is: utilize the Chinese herbal medicine of motherland's traditional medicine to carry out reasonable compatibility, treatment cost is lower, and side effect is less, and therapeutic effect is remarkable.
The specific embodiment
Further illustrate the curative effect of above-mentioned composition with 40 routine patients of clinical treatment, 40 routine patients all are diagnosed as hepatitis B by national Diagnosis of Viral Hapatitis standard, get rid of the patient who is associated with Other diseases, comprise the liver cirrhosis, the hepatocarcinoma that are caused by hepatitis B, and the other medicines factor affected the treatment, wherein, male 28 examples, female's 12 examples, the course of disease is the shortest 1 month, the longest 8 years, positive 40 examples of HBSAg, positive 12 examples of HBeAg, positive 38 examples of HBCAb, positive 25 examples of HBeAb, ALT 31 examples that raise, AST 35 examples that raise, serum total bilirubin 19 examples that raise.The patient is above-mentioned capsule oral, one time 20,3 times on the one, two months is a course for the treatment of, takes 4 courses for the treatment of, cures 30 examples (symptom all disappears, and three sun are turned out cloudy), accounts for 75%; Effective 7 examples (symptom disappears substantially, and three sun are turned out cloudy 1 or 2) account for 17.5%; Invalid (symptom is unchanged, and three sun still exist) 3 examples, account for 7.5%, total cure rate 75%.Total effective rate is 92.5%.
Claims (1)
1. a pharmaceutical composition for the treatment of hepatitis B, is characterized in that: Radix Et Rhizoma Rhei 10 grams, Radix Curcumae 15 grams, Radix Bupleuri 10 grams, Radix Scutellariae 15 grams, Rhizoma Polygoni Cuspidati 15 grams, Hedyotidis Diffusae 15 grams, Herba Artemisiae Scopariae 20 grams, Carapax Trionycis 30 grams, Radix Salviae Miltiorrhizae 20 grams, the Rhizoma Atractylodis Macrocephalae 20 grams, Rhizoma Dioscoreae 30 grams, Fructus Aurantii Immaturus 15 grams, Radix Ginseng Rubra 15 grams, the Radix Astragali 40 grams, the Radix Rehmanniae 30 grams, Colla cornus cervi 10 grams, Fructus Gardeniae 15 grams.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110250121.8A CN102949658B (en) | 2011-08-18 | 2011-08-18 | Drug formula for treating hepatitis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110250121.8A CN102949658B (en) | 2011-08-18 | 2011-08-18 | Drug formula for treating hepatitis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102949658A CN102949658A (en) | 2013-03-06 |
| CN102949658B true CN102949658B (en) | 2014-01-08 |
Family
ID=47759417
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201110250121.8A Active CN102949658B (en) | 2011-08-18 | 2011-08-18 | Drug formula for treating hepatitis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102949658B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103948875A (en) * | 2014-05-13 | 2014-07-30 | 梁景山 | Medicine for treating hepatitis B and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1113779A (en) * | 1994-06-17 | 1995-12-27 | 殷广全 | Anti- hepatitis B preparation |
| CN1160559A (en) * | 1996-11-30 | 1997-10-01 | 李泽良 | Hepatitis B curing toxin-dissipating pill |
| CN101647948A (en) * | 2009-05-05 | 2010-02-17 | 周菊彦 | Traditional Chinese medicine for treating viral hepatitis B and initial hepatocirrhosis and preparation method thereof |
-
2011
- 2011-08-18 CN CN201110250121.8A patent/CN102949658B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1113779A (en) * | 1994-06-17 | 1995-12-27 | 殷广全 | Anti- hepatitis B preparation |
| CN1160559A (en) * | 1996-11-30 | 1997-10-01 | 李泽良 | Hepatitis B curing toxin-dissipating pill |
| CN101647948A (en) * | 2009-05-05 | 2010-02-17 | 周菊彦 | Traditional Chinese medicine for treating viral hepatitis B and initial hepatocirrhosis and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102949658A (en) | 2013-03-06 |
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Effective date of registration: 20210316 Address after: No.42-1, sangyuan Road, Licheng District, Jinan City, Shandong Province, 250100 Patentee after: Liu Jinbo Address before: 734200 community 9, kangzhai village, Xinhua Township, Linze County, Gansu Province Patentee before: Zhang Zhitong |
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Effective date of registration: 20220105 Address after: 223800 No. 24, xiaoguanfang group, Shayu village, Yanji Town, Shuyang County, Suqian City, Jiangsu Province Patentee after: Wang Yilin Address before: No.42-1, sangyuan Road, Licheng District, Jinan City, Shandong Province, 250100 Patentee before: Liu Jinbo |
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Effective date of registration: 20220916 Address after: Room 203, Building 3, Hangzhou Xuanhao Holiday Hotel, No. 984, Xixi Road, Liuliu Street, Xihu District, Hangzhou City, Zhejiang Province 310000 Patentee after: China Zhongjian An (Hangzhou) Molecular Medicine Technology Co.,Ltd. Address before: 223800 No. 24, xiaoguanfang group, Shayu village, Yanji Town, Shuyang County, Suqian City, Jiangsu Province Patentee before: Wang Yilin |
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