CN102949605B - Medicine formula for treating non-specificity ulcerative colitis - Google Patents
Medicine formula for treating non-specificity ulcerative colitis Download PDFInfo
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- CN102949605B CN102949605B CN201110250106.3A CN201110250106A CN102949605B CN 102949605 B CN102949605 B CN 102949605B CN 201110250106 A CN201110250106 A CN 201110250106A CN 102949605 B CN102949605 B CN 102949605B
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- radix
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- ulcerative colitis
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- 206010009900 Colitis ulcerative Diseases 0.000 title claims abstract description 8
- 201000006704 Ulcerative Colitis Diseases 0.000 title claims abstract description 8
- 239000003814 drug Substances 0.000 title abstract description 16
- 229940079593 drug Drugs 0.000 title abstract description 5
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims abstract description 5
- 239000004863 Frankincense Substances 0.000 claims abstract description 4
- 235000009388 Parthenocissus quinquefolia Nutrition 0.000 claims abstract description 4
- 210000000582 semen Anatomy 0.000 claims abstract description 4
- 239000009636 Huang Qi Substances 0.000 claims description 4
- 241000563984 Ampelopsis Species 0.000 claims description 3
- 241000717739 Boswellia sacra Species 0.000 claims description 3
- 241000756943 Codonopsis Species 0.000 claims description 3
- 241001057584 Myrrha Species 0.000 claims description 3
- 239000010135 fructus aurantii immaturus Substances 0.000 claims description 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 230000000694 effects Effects 0.000 abstract description 8
- 239000002775 capsule Substances 0.000 abstract description 3
- 239000000843 powder Substances 0.000 abstract description 2
- 241000045403 Astragalus propinquus Species 0.000 abstract 1
- 241001313857 Bletilla striata Species 0.000 abstract 1
- 235000003717 Boswellia sacra Nutrition 0.000 abstract 1
- 240000007551 Boswellia serrata Species 0.000 abstract 1
- 235000012035 Boswellia serrata Nutrition 0.000 abstract 1
- 244000183685 Citrus aurantium Species 0.000 abstract 1
- 235000007716 Citrus aurantium Nutrition 0.000 abstract 1
- 241000007126 Codonopsis pilosula Species 0.000 abstract 1
- 240000007311 Commiphora myrrha Species 0.000 abstract 1
- 235000006965 Commiphora myrrha Nutrition 0.000 abstract 1
- 235000002722 Dioscorea batatas Nutrition 0.000 abstract 1
- 235000006536 Dioscorea esculenta Nutrition 0.000 abstract 1
- 240000001811 Dioscorea oppositifolia Species 0.000 abstract 1
- 235000003416 Dioscorea oppositifolia Nutrition 0.000 abstract 1
- 241000218671 Ephedra Species 0.000 abstract 1
- 240000005779 Jasminum multiflorum Species 0.000 abstract 1
- 235000010254 Jasminum officinale Nutrition 0.000 abstract 1
- 240000005385 Jasminum sambac Species 0.000 abstract 1
- 235000007265 Myrrhis odorata Nutrition 0.000 abstract 1
- 240000001659 Oldenlandia diffusa Species 0.000 abstract 1
- 241000219099 Parthenocissus quinquefolia Species 0.000 abstract 1
- 241000405414 Rehmannia Species 0.000 abstract 1
- 240000004980 Rheum officinale Species 0.000 abstract 1
- 235000008081 Rheum officinale Nutrition 0.000 abstract 1
- 240000004534 Scutellaria baicalensis Species 0.000 abstract 1
- 235000017089 Scutellaria baicalensis Nutrition 0.000 abstract 1
- 240000008488 Thlaspi arvense Species 0.000 abstract 1
- 235000008214 Thlaspi arvense Nutrition 0.000 abstract 1
- 235000006533 astragalus Nutrition 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 description 5
- 208000025865 Ulcer Diseases 0.000 description 4
- 239000008280 blood Substances 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 4
- 231100000397 ulcer Toxicity 0.000 description 4
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 231100000915 pathological change Toxicity 0.000 description 3
- 230000036285 pathological change Effects 0.000 description 3
- 206010007247 Carbuncle Diseases 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 238000002052 colonoscopy Methods 0.000 description 2
- 238000005469 granulation Methods 0.000 description 2
- 230000003179 granulation Effects 0.000 description 2
- 230000000968 intestinal effect Effects 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 206010000077 Abdominal mass Diseases 0.000 description 1
- 206010003011 Appendicitis Diseases 0.000 description 1
- 206010020565 Hyperaemia Diseases 0.000 description 1
- 206010061297 Mucosal erosion Diseases 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 208000005392 Spasm Diseases 0.000 description 1
- 230000009285 allergic inflammation Effects 0.000 description 1
- 230000000259 anti-tumor effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 210000001842 enterocyte Anatomy 0.000 description 1
- 210000002919 epithelial cell Anatomy 0.000 description 1
- 230000005714 functional activity Effects 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 230000001506 immunosuppresive effect Effects 0.000 description 1
- 210000004347 intestinal mucosa Anatomy 0.000 description 1
- 230000009856 intestinal mucosal lesion Effects 0.000 description 1
- 208000003243 intestinal obstruction Diseases 0.000 description 1
- 206010022694 intestinal perforation Diseases 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000001338 necrotic effect Effects 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
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Abstract
The invention discloses a medicine formula for treating non-specificity ulcerative colitis. The medicine formula comprises the following components according to a unit of gram: 8g of rheum officinale, 5g of frankincense, 20 g of scutellaria baicalensis, 5g of myrrh, 15g of hedyotis diffusa, 30g of semen coicis, 15g of radix ampelopsis, 15g of bletilla striata, 15g of Chinese starjasmine stem, 20g of rhizoma atractylodis macrocephalae, 30g of Chinese yam, 15g of immature bitter orange, 15g of codonopsis pilosula, 20g of astragalus mongholicus, 40g of rehmannia root, 15g of jasmine, 15g of field pennycress, 15g of moutan bark, 20g of Hangzhou radix paeoniae alba and 6g of ephedra. The medicines are pulverized according to a weight proportion and are manufactured to be 80-100 meshes of powder; the medicines are filled into hollow capsules of 0.5g; 10 capsules are taken for one time and three times in one day; the medicines are orally taken for two mouths used as a first course of treatment, and are orally taken for three courses of treatment, so that a good curative effect is generally achieved.
Description
Affiliated technical field
The present invention relates to a kind of medicament composing prescription for the treatment of nonspecific ulcerative colitis.
Background technology
Nonspecific ulcerative colitis is covered by among the scope of motherland's medical science acute appendicitis, chronic dysentery, and the damp and hot heresy that has intestinal to be formed by various toxin hot and suffocating more, QI and blood cohesion forms.More, ulcer is prolonged does not hold back the touching difficulty of the course of disease, easily causes intestinal obstruction, intestinal perforation, the even canceration having, at present, the not effective especially Therapeutic Method of this disease.
Summary of the invention
The object of the present invention is to provide a kind of medicament composing prescription of very effective treatment nonspecific ulcerative colitis, plan method for the treatment of of the present invention is: removing toxicity for eliminating carbuncles, promoting blood circulation and detumescence, removing the necrotic tissue and promoting granulation, strengthening the body resistance.
Medicament composing prescription of the present invention is (in grams): Radix Et Rhizoma Rhei 8, Olibanum 5, Radix Scutellariae 20, Myrrha 5, Hedyotidis Diffusae 15, SEMEN COICIS 30, Radix Ampelopsis 15, the Pseudobulbus Bletillae (Rhizoma Bletillae) 15, Caulis Trachelospermi 15, the Rhizoma Atractylodis Macrocephalae 20, Rhizoma Dioscoreae 30, Fructus Aurantii Immaturus 15, Radix Codonopsis 15, the Radix Astragali 20, the Radix Rehmanniae 40, Fructus Gardeniae 15, Herba Patriniae 15, Cortex Moutan 15, Radix Paeoniae Alba 20, Herba Ephedrae 6.
In side: under Radix Et Rhizoma Rhei bitter cold is rushed down, the Fructus Aurantii Immaturus circulation of qi promoting painful abdominal mass that disappears, compatibility, discharges rapidly damp and hot heresy from stool mutually; Olibanum, Myrrha promoting blood circulation and detumescence, SEMEN COICIS, Herba Patriniae, Cortex Moutan, Hedyotidis Diffusae match there is heat-clearing and toxic substances removing, the effect of dampness removing eliminating carbuncle, dissipating blood stasis evacuation of pus.In addition, Hedyotidis Diffusae has antitumor action; Radix Ampelopsis, the Pseudobulbus Bletillae (Rhizoma Bletillae), Caulis Trachelospermi match there is sore, the effect of granulation promoting, hemostasia and detumescence; The Rhizoma Atractylodis Macrocephalae, Rhizoma Dioscoreae, Radix Codonopsis, the Radix Astragali, the Radix Rehmanniae, the Radix Paeoniae Alba match, and have the effect of air making-up and spleen enlivening, nourishing YIN and benefiting blood; Can improve the ability of ulcer healing.In addition, the Radix Astragali has the effect of free radical resisting, can cancerate by prevention of intestinal tract epithelial cell.The Radix Paeoniae Alba can be removed the spasm of intestinal smooth, and Radix Scutellariae is the warm of the part of the body cavity above the diaphragm housing the heart and lungs clearly, and Fructus Gardeniae can let out the fire of three warmers.According to modern medicine study: Radix Scutellariae can suppress the release of allergic inflammation medium, and Fructus Gardeniae has immunosuppressive action, and above-mentioned two medicines match, the antibody of resistive connection enterocyte can not be produced, thereby ulcer is healed very soon, no longer recurrence, Herba Ephedrae has lung qi dispersing, the effect of harmonizing the functional activities of vital QI.
Said medicine is pulverized by weight proportion, is made 80-100 object powder, pack the Capsules of 0.5g into, one time 10,3 times on the one are oral, be a course for the treatment of February, takes 3 courses for the treatment of, generally can receive good curative effect.
This beneficial effect of the invention is: utilize the Chinese herbal medicine of motherland's traditional medicine to carry out reasonable compatibility, treatment cost is lower, and side effect is less, and therapeutic effect is remarkable.
The specific embodiment
The 37 routine nonspecific ulcerative colitis of clinical treatment of take illustrate the effectiveness of said medicine as example, in 37 routine patients, man's 25 examples, female's 12 examples, age 28-56 year, the shortest person of the course of disease 2 months, elder 11 years, according to colonoscope finding, local patholoic change is divided into three kinds: pathological changes that (1) is slight: take mucous hyperemia edema as main; (2) moderate pathological changes: take mucosal erosion oozing of blood as main; (3) severe pathological changes: take mucosal surface ulcer as feature.Patient is by 10 of said medicine one time, and 3 times on the one oral, within 2 months, is a course for the treatment of, take 3 courses for the treatment of, slight 16 routine patients cure (symptom is eliminated, and colonoscopy intestinal mucosa is normal) completely, moderate patient's 9 examples, cure 8 example 1 examples take a turn for the better (symptom alleviates, colonoscopy, intestinal mucosal lesion has obvious change), severe patient's 12 examples, 6 examples are cured, and 4 examples take a turn for the better, and 2 examples are not adhered to treatment.
Claims (1)
1. a pharmaceutical composition for the treatment of nonspecific ulcerative colitis, is characterized in that: pharmaceutical composition is in grams: Radix Et Rhizoma Rhei 8, Olibanum 5, Radix Scutellariae 20, Myrrha 5, Hedyotidis Diffusae 15, SEMEN COICIS 30, Radix Ampelopsis 15, the Pseudobulbus Bletillae (Rhizoma Bletillae) 15, Caulis Trachelospermi 15, the Rhizoma Atractylodis Macrocephalae 20, Rhizoma Dioscoreae 30, Fructus Aurantii Immaturus 15, Radix Codonopsis 15, the Radix Astragali 20, the Radix Rehmanniae 40, Fructus Gardeniae 15, Herba Patriniae 15, Cortex Moutan 15, Radix Paeoniae Alba 20, Herba Ephedrae 6.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110250106.3A CN102949605B (en) | 2011-08-18 | 2011-08-18 | Medicine formula for treating non-specificity ulcerative colitis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110250106.3A CN102949605B (en) | 2011-08-18 | 2011-08-18 | Medicine formula for treating non-specificity ulcerative colitis |
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| Publication Number | Publication Date |
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| CN102949605A CN102949605A (en) | 2013-03-06 |
| CN102949605B true CN102949605B (en) | 2014-08-13 |
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| CN201110250106.3A Active CN102949605B (en) | 2011-08-18 | 2011-08-18 | Medicine formula for treating non-specificity ulcerative colitis |
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Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115349597A (en) * | 2022-09-06 | 2022-11-18 | 宁夏医科大学 | Medicated diet for ulcerative colitis |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101991793A (en) * | 2009-08-20 | 2011-03-30 | 张志通 | Medicine for treating nonspecific ulcerative colitis |
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2011
- 2011-08-18 CN CN201110250106.3A patent/CN102949605B/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101991793A (en) * | 2009-08-20 | 2011-03-30 | 张志通 | Medicine for treating nonspecific ulcerative colitis |
Non-Patent Citations (4)
| Title |
|---|
| 慢性非特异性溃疡性结肠炎的中医治疗进展;王晓男等;《中华中医药学刊》;20090430;第27卷(第04期);784-786 * |
| 溃疡性结肠炎中医药治疗进展;黄烈生;《黑龙江中医药》;20011231(第03期);63-65 * |
| 王晓男等.慢性非特异性溃疡性结肠炎的中医治疗进展.《中华中医药学刊》.2009,第27卷(第04期),784-786. |
| 黄烈生.溃疡性结肠炎中医药治疗进展.《黑龙江中医药》.2001,(第03期),63-65. |
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| CN102949605A (en) | 2013-03-06 |
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Effective date of registration: 20210319 Address after: No.42-1, sangyuan Road, Licheng District, Jinan City, Shandong Province, 250100 Patentee after: Liu Jinbo Address before: 734200 community 9, kangzhai village, Xinhua Township, Linze County, Gansu Province Patentee before: Zhang Zhitong |
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Addressee: Liu Jinbo Document name: Notification of eligibility |
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Effective date of registration: 20220906 Address after: No. 16, Qinhuaihe Road, Yantai Development Zone, Yantai City, Shandong Province, 264000 Patentee after: YANTAI ZHENGFANG PHARMACEUTICAL Co.,Ltd. Address before: No.42-1, sangyuan Road, Licheng District, Jinan City, Shandong Province, 250100 Patentee before: Liu Jinbo |