CN102772560B - Traditional Chinese medicine composition for treating radiation-induced pulmonary injury - Google Patents
Traditional Chinese medicine composition for treating radiation-induced pulmonary injury Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine composition for treating radiation-induced pulmonary injury. The traditional Chinese medicine composition is characterized by being prepared from the following bulk drugs by weight: 8-10g of codonopsis pilosula, 6-8g of radix astragali, 4-6g of Chinese angelica, 6-8g of radix scutellariae, 6-8g of cordate houttuynia, 8-10g of figwort root, 6-9g of dried rehmannia root, 4-6g of salvia miltiorrhiza, 6-8g of radix paeoniae alba, 4-6g of ligusticum wallichii, 4-6g of bitter almond, 6-8g of dried orange peel, 4-6g of platycodon grandiflorum, 4-6g of earthworm, 6-8g of frankincense, 6-8g of myrrh and 4-6g of liquorice. The traditional Chinese medicine composition has the beneficial effects of strengthening the body resistance and eliminating pathogenic factors, nourishing yin and promoting the secretion of saliva or body fluid, moistening lung for arresting cough, and invigorating blood and removing stasis, is rapid in taking effect and high in curative effect, and has no toxic or side effect. Diagnosis and treatment based on the overall analysis of the illnesses and the conditions of patients can be performed in clinic.
Description
Technical field
Invention relates to a kind of Chinese medicine composition of radiotherapy injury of lung.
Background technology
As everyone knows, the damage of radioactivity pulmonary is the complication that the breast tumor radiotherapy causes, the traditional Chinese medical science is thought: belong in the lonizing radiation pyretic toxicity lung network of invading, burn, impairment of body fluid consumption gas, blood network stasis blocking.More than symptom within after radiotherapy 2～3 weeks, occurring, often irritant, dry cough, companion are out of breath, cardiopalmus and chest pain, do not generate heat or low grade fever, even high heat are arranged.Out of breath with pulmonary fibrosis increase the weight of to be the aggravation of carrying out property, easily producing respiratory tract infection increases the weight of respiratory symptom, occurs dysphagia during concurrent radiation esophagitis.If position atrophoderma, hardening are radiated in health check-up as seen, pulmonary's audible and dry, moist rale and crunch, pulmonary extensively, serious fibrosis, finally cause pulmonary function high pressure and pulmonary heart disease corresponding sign to occur.Adopt at present antibiotics, hormone to alleviate, very unfavorable to the patient's that has a delicate constitution after radiotherapy health.
Summary of the invention
Technical problem to be solved by this invention is in order to overcome technical deficiency, and the Chinese medicine composition of a kind of radiotherapy injury of lung that curative effect is high, side effect is little is provided.
The technical scheme that its technical problem that the present invention solves adopts is to it is characterized in that being comprised of the crude drug component of following proportioning: Radix Codonopsis 8～10g, the Radix Astragali 6～8g, Radix Angelicae Sinensis 4～6g, Radix Scutellariae 6～8g, Herba Houttuyniae 6～8g, Radix Scrophulariae 8～10g, Radix Rehmanniae 6～9g, Radix Salviae Miltiorrhizae 4～6g, the Radix Paeoniae Alba 6～8g, Rhizoma Chuanxiong 4～6g, Semen Armeniacae Amarum 4～6g, Pericarpium Citri Reticulatae 6～8g, Radix Platycodonis 4～6g, Pheretima 4～6g, Olibanum 6～8g, Myrrha 6～8g, Radix Glycyrrhizae 4～6g.
The invention has the beneficial effects as follows: have the effect of strengthening vital QI to eliminate pathogenic factors, Yin-nourishing and body fluid promoting, nourishing the lung to arrest cough, promoting blood circulation to remove blood stasis, its effect is fast, and curative effect is high, has no side effect.Clinically often according to different pattern of syndrome determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs.
Radix Codonopsis in Chinese medicine of the present invention has invigorating the spleen and replenishing QI, the effect of spleen invigorating lung benefiting.Modern study, Radix Codonopsis is containing various saccharides, phenols, sterol, volatile oil, scutellarein glucosid, Saponin and Alkaloid, has enhancing immunity, blood vessel dilating, blood pressure lowering, improves microcirculation, strengthens the effect such as hemopoietic function.The Radix Astragali is leguminous herbaceous plant, and function cures mainly: the effects such as invigorating QI to consolidate the body surface resistance, diuretic detumescent, expelling pus and toxin by strengthening QI, granulation promoting, and modern study, the Radix Astragali has enhancing human body immunity function, radioprotective, diuresis and antibacterial action more widely.Radix Angelicae Sinensis is warm in nature, sweet in the mouth, suffering.Function cures mainly: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Modern study, have the effect of antitumor, radioprotective, analgesia, antiinflammatory.The Radix Scutellariae hardship, cold.Function cures mainly: heat clearing and damp drying is arranged, removing toxic substances.Cure mainly epidemic febrile disease, cough due to lung-heat, damp and hot jaundice, pneumonia, carbuncle furuncle ....The Herba Houttuyniae cold nature, bitter in the mouth.Return lung meridian, bladder, large intestine channel.Function cures mainly: heat-clearing and toxic substances removing, removing pus and relieving carbuncle, inducing diuresis for treating stranguria syndrome.Modern study, have antibiotic, strengthen immunity, radioprotective, antiviral effect.Radix Scrophulariae sweet-bitter flavor, salty, cold nature.Function cures mainly: clearing away heat and cooling blood, and eliminating fire and detoxication, YIN nourishing, join both equal energy clearing away heat and cooling blood of Radix Rehmanniae, and YIN nourishing and the production of body fluid promoting, enter nutrient blood with controlling heat, consumption of YIN caused by febrile disease, the cards such as yin asthenia generating intrinsic heat.Modern study, have heart tonifying, antibacterial action." detailed outline ": nourishing YIN to lower pathogenic fire, separate the speckle poison, throat, diuresis stasis.Radix Rehmanniae has heat clearing away, promotes the production of body fluid, moisturizes, the effect of laxation, removing blood stasis with potent drugs, tissue regeneration promoting, pain relieving.The Radix Salviae Miltiorrhizae perennial herb, bitter in the mouth, cold nature.GUIXIN, Liver Channel.Function cures mainly: promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind.Modern study, have the reparation of promotion tissue and the effect of regeneration.The acid of Radix Paeoniae Alba bitter in the mouth, cool in nature.Enter liver, spleen channel.Function cures mainly: nourishing blood to suppress the hyperactive liver, and slow middle pain relieving, yin fluid astringing is received antiperspirant." property of medicine opinion ": " control pathogen of the lung gas, Fu Zhong Xu pain, vim and vigour are gathered, and logical a surname's internal organs are gathered around gas." the hot temperature of Rhizoma Chuanxiong is fragrant dry, for the various diseases of stagnation of blood stasis, wind-expelling pain-stopping, effectiveness is excellent, and crude preparation by using examination Rhizoma Chuanxiong water solublity is tested, and the radiation exposure of rat, mice and dog is damaged protective effect is all arranged with chlormethine.Therefore there is radiation resistance.The Pericarpium Citri Reticulatae acrid in the mouth, warm in nature, there is regulating qi-flowing for strengthening spleen, in tune, dampness, the effect of reducing phlegm, its temperature can circulation of qi promoting, and suffering can be dispersed, bitter and sluice.The function of Radix Platycodonis cures mainly: lung qi dispersing, eliminate the phlegm, sore-throat relieving, evacuation of pus." daily book on Chinese herbal medicine ": can fall apart and can rush down, can temperature can mend, the diaphragm gas that can disappear, saliva reduces phlegm.The Semen Armeniacae Amarum function cures mainly: sending down the abnormal ascending QI, relieving cough and asthma, loosening bowel to relieve constipation.For cough and asthma, fullness in the chest abundant expectoration, blood deficiency Tianjin is withered, the dryness of the intestine constipation.Modern study, have anti-inflammatory and antalgic, antitumor action.Pheretima is cold in nature, salty in the mouth.Function cures mainly: heat clearing away arresting convulsion, dredging collateral, relieving asthma, and diuresis.Modern study, have antitumaous effect.Olibanum acrid in the mouth hardship, warm in nature.Function cures mainly: regulating qi and activating blood, analgesic therapy, chase after poison." not Lu ": treat the edema due to wind pathogen poison swollen, remove bad odor.Treat the urticaria poison of itching.The Myrrha bitter in the mouth, suffering, property is flat.Function cures mainly: loose blood blood stasis removing, subduing swelling and relieving pain.Join Olibanum, promoting blood circulation to remove blood stasis, circulation of qi promoting relaxing muscles and tendons.Radix Glycyrrhizae has invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, the effect of coordinating the actions of various ingredients in a prescription.Above all medicines match, bring out the best in each other.
The present invention follows the prescriptions principle of the traditional Chinese medical science, is decocted in water for oral dose.The present invention is through clinical verification: cure rate 85.2%; Total effective rate 95.4%, toxic and side effects is little.
The specific embodiment
Below in conjunction with embodiment, the invention will be further described:
Embodiment 1: a kind of Chinese medicine composition of radiotherapy injury of lung is characterized in that by following proportioning weighting raw materials: Radix Codonopsis 8～10g, the Radix Astragali 6～8g, Radix Angelicae Sinensis 4～6g, Radix Scutellariae 6～8g, Herba Houttuyniae 6～8g, Radix Scrophulariae 8～10g, Radix Rehmanniae 6～9g, Radix Salviae Miltiorrhizae 4～6g, the Radix Paeoniae Alba 6～8g, Rhizoma Chuanxiong 4～6g, Semen Armeniacae Amarum 4～6g, Pericarpium Citri Reticulatae 6～8g, Radix Platycodonis 4～6g, Pheretima 4～6g, Olibanum 6～8g, Myrrha 6～8g, Radix Glycyrrhizae 4～6g.
Embodiment 2: a kind of Chinese medicine composition of radiotherapy injury of lung is characterized in that by following proportioning weighting raw materials: Radix Codonopsis 10g, Radix Astragali 6g, Radix Angelicae Sinensis 4g, Radix Scutellariae 6g, Herba Houttuyniae 8g, Radix Scrophulariae 8g, Radix Rehmanniae 6g, Radix Salviae Miltiorrhizae 6g, Radix Paeoniae Alba 6g, Rhizoma Chuanxiong 4g, Semen Armeniacae Amarum 4g, Pericarpium Citri Reticulatae 8g, Radix Platycodonis 4g, Pheretima 4g, Olibanum 6g, Myrrha 6g, Radix Glycyrrhizae 4g.
Clinical efficacy is summed up:
One, physical data: selective emission pulmonary lesion patient is totally 68 examples, wherein: male 44 examples, female's 24 examples; In age 31-62 year, average 51 years old, in the course of disease 2 months, average 45.2 days, all through hospital above county level, make a definite diagnosis and implement above-mentioned treatment.
Two, diagnostic criteria: radioactivity pulmonary damage, pulmonary's radiotherapy history is arranged, show as the clinical symptoms such as cough, uncomfortable in chest, chest pain, dyspnea and low grade fever.Sign: but the lighter's Non Apparent Abnormality, and the severe one respiratory murmur reduces, and dry, moist rales occur.X-ray examination finds that netted, the irregular fuzzy shape shade in edge appears in exposure pulmonary, can be with a series of physiology of radiation damage, pathology and clinical manifestations such as hemopoietic, immunity and digestive system.
Three, curative effect judging standard:
Cure: clinical symptoms disappears fully, and imaging examination pulmonary is normal.
Take a turn for the better: clinical symptoms is improved, and the imaging examination pulmonary shadow alleviates.
Invalid: symptom is without improving or increasing the weight of.
Four, method of administration: all crude drug of the present invention are chosen, mixed after immersion add decocting and become decoction, every dose of 200ml, every day 2 times, early, late sub-service.
Five, therapeutic effect: the present invention treats 68 routine patients: wherein cure 58 examples, 7 examples that take a turn for the better, 3 examples more, cure rate 85.2%; Total effective rate 95.5%.
Six, model case
1, Lee XX, the man, 46 years old, in February, 2009 was medical.Main suit's lung cancer with brain metastasis tumor postoperation radiotherapy is after 28 days, because of cough, expectoration, pant 1 week, through taking cephamycin capsule and cough mixture poor effect, auscultation: dry, moist rales appear in pulmonary, X-ray examination: the blur margin shade appears in exposure pulmonary, the damage of prompting radioactivity pulmonary.The patient requires to take 15 doses, Chinese medicine of the present invention, and clinical symptoms disappears fully, and X-ray examination pulmonary is normal.So far not recurrence.
2, clump XX, the female, 46 years old, in June, 2010 was medical.Patient main suit's postoperation radiotherapy 20 days, cough, cough a small amount of white sputum crudum, uncomfortable in chest, chest pain sometimes.X-ray examination: netted, the irregular fuzzy shape shade in edge appears in pulmonary, through taking 20 doses, Chinese medicine of the present invention, and remission, drug withdrawal 2 days, continued to take 1 course for the treatment of, and 15 doses, clinical symptoms disappears fully, and X-ray examination pulmonary is normal.So far not recurrence.
3, Liu XX, the female, 38 years old, in May, 2011 was medical, the breast carcinoma month after operation, after radiotherapy 1 week, because of dry cough, chest pain.Have a medical check-up: dry rale appears in pulmonary.X-ray examination: prompting has mild fibrosis.The patient requires to take after 20 doses, Chinese medicine of the present invention drug withdrawal 2 days, takes again 10 doses, and clinical symptoms disappears fully, and X-ray examination pulmonary is normal.So far not recurrence.
Claims (1)
1. the Chinese medicine composition of a radiotherapy injury of lung, is characterized in that it is comprised of the crude drug of following proportioning: Radix Codonopsis 8～10g, the Radix Astragali 6～8g, Radix Angelicae Sinensis 4～6g, Radix Scutellariae 6～8g, Herba Houttuyniae 6～8g, Radix Scrophulariae 8～10g, Radix Rehmanniae 6～9g, Radix Salviae Miltiorrhizae 4～6g, the Radix Paeoniae Alba 6～8g, Rhizoma Chuanxiong 4～6g, Semen Armeniacae Amarum 4～6g, Pericarpium Citri Reticulatae 6～8g, Radix Platycodonis 4～6g, Pheretima 4～6g, Olibanum 6～8g, Myrrha 6～8g, Radix Glycyrrhizae 4～6g.
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Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103071120B (en) * | 2013-01-31 | 2014-04-30 | 张玉康 | Medicine for treating silicosis |
| CN103877397B (en) * | 2014-04-19 | 2016-03-30 | 岳贤文 | A kind of medicine of radiotherapy injury of lung and preparation method |
| CN105168871A (en) * | 2015-07-14 | 2015-12-23 | 武大鹏 | Traditional Chinese medicinal composition for preventing and treating acute irradiation lung injury |
| CN109893613A (en) * | 2019-01-25 | 2019-06-18 | 中国人民解放军西部战区总医院 | The Chinese native medicine compound prescription pellet and preparation method thereof of therapeutic radiation injury of lungs |
| CN115381894B (en) * | 2022-08-26 | 2023-09-22 | 金陵科技学院 | Traditional Chinese medicine composition and preparation method and application thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1552420A (en) * | 2003-09-02 | 2004-12-08 | 丽珠集团利民制药厂 | Use of pilose asiabell and astragalus composition in preventing and treatnig acute pulmonary hurt |
| CN1608654A (en) * | 2003-10-17 | 2005-04-27 | 徐万富 | Chinese medicine for treating intrapulmonic infection and SARS |
-
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1552420A (en) * | 2003-09-02 | 2004-12-08 | 丽珠集团利民制药厂 | Use of pilose asiabell and astragalus composition in preventing and treatnig acute pulmonary hurt |
| CN1608654A (en) * | 2003-10-17 | 2005-04-27 | 徐万富 | Chinese medicine for treating intrapulmonic infection and SARS |
Non-Patent Citations (4)
| Title |
|---|
| 崔维强.放射性肺炎的中医药治疗进展.《陕西中医》.2007,第28卷(第11期),第1569-1571页. |
| 张娟，闫永建.中医药治疗肺纤维化研究进展.《山东中医药大学学报》.2009,第33卷(第1期),第81-85页. * |
| 放射性肺炎的中医药治疗进展;崔维强;《陕西中医》;20071130;第28卷(第11期);第1569-1571页 * |
| 王景娜,刘莉.中药在放射性肺损伤防护中的作用.《现代肿瘤医学》.2008,第16卷(第10期),第1800-1803页. * |
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