CN103006877B - Formula for systemic lupus erythematosus treatment drug - Google Patents
Formula for systemic lupus erythematosus treatment drug Download PDFInfo
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- CN103006877B CN103006877B CN2011102501082A CN201110250108A CN103006877B CN 103006877 B CN103006877 B CN 103006877B CN 2011102501082 A CN2011102501082 A CN 2011102501082A CN 201110250108 A CN201110250108 A CN 201110250108A CN 103006877 B CN103006877 B CN 103006877B
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- radix
- root
- lupus erythematosus
- systemic lupus
- pills
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- 201000000596 systemic lupus erythematosus Diseases 0.000 title claims abstract description 11
- 239000003814 drug Substances 0.000 title abstract description 15
- 229940079593 drug Drugs 0.000 title abstract description 5
- 239000010135 fructus aurantii immaturus Substances 0.000 claims description 4
- 241000628997 Flos Species 0.000 claims description 3
- 239000009636 Huang Qi Substances 0.000 claims description 3
- 241000222640 Polyporus Species 0.000 claims description 3
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims description 3
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims description 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 7
- 239000006187 pill Substances 0.000 abstract description 4
- 239000000843 powder Substances 0.000 abstract description 3
- 241001061264 Astragalus Species 0.000 abstract 1
- 235000010110 Astragalus glycyphyllos Nutrition 0.000 abstract 1
- 241000132012 Atractylodes Species 0.000 abstract 1
- 244000236521 Bupleurum rotundifolium Species 0.000 abstract 1
- 235000015221 Bupleurum rotundifolium Nutrition 0.000 abstract 1
- 235000007516 Chrysanthemum Nutrition 0.000 abstract 1
- 244000189548 Chrysanthemum x morifolium Species 0.000 abstract 1
- 244000183685 Citrus aurantium Species 0.000 abstract 1
- 235000007716 Citrus aurantium Nutrition 0.000 abstract 1
- 241000037740 Coptis chinensis Species 0.000 abstract 1
- 241001465251 Ephedra sinica Species 0.000 abstract 1
- 241000576429 Forsythia suspensa Species 0.000 abstract 1
- 244000111489 Gardenia augusta Species 0.000 abstract 1
- 235000018958 Gardenia augusta Nutrition 0.000 abstract 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 abstract 1
- 244000303040 Glycyrrhiza glabra Species 0.000 abstract 1
- 235000017443 Hedysarum boreale Nutrition 0.000 abstract 1
- 235000007858 Hedysarum occidentale Nutrition 0.000 abstract 1
- 240000007890 Leonurus cardiaca Species 0.000 abstract 1
- 235000000807 Leonurus cardiaca ssp. cardiaca Nutrition 0.000 abstract 1
- 235000000802 Leonurus cardiaca ssp. villosus Nutrition 0.000 abstract 1
- 241000212322 Levisticum officinale Species 0.000 abstract 1
- 244000236658 Paeonia lactiflora Species 0.000 abstract 1
- 235000008598 Paeonia lactiflora Nutrition 0.000 abstract 1
- 244000248825 Peltandra virginica Species 0.000 abstract 1
- 235000001188 Peltandra virginica Nutrition 0.000 abstract 1
- 241000972673 Phellodendron amurense Species 0.000 abstract 1
- 235000008599 Poria cocos Nutrition 0.000 abstract 1
- 244000081426 Ranunculus ficaria Species 0.000 abstract 1
- 235000002226 Ranunculus ficaria Nutrition 0.000 abstract 1
- 241000405414 Rehmannia Species 0.000 abstract 1
- 241000219061 Rheum Species 0.000 abstract 1
- 241000304195 Salvia miltiorrhiza Species 0.000 abstract 1
- 235000011135 Salvia miltiorrhiza Nutrition 0.000 abstract 1
- 240000004534 Scutellaria baicalensis Species 0.000 abstract 1
- 235000017089 Scutellaria baicalensis Nutrition 0.000 abstract 1
- 241000270666 Testudines Species 0.000 abstract 1
- 235000006533 astragalus Nutrition 0.000 abstract 1
- 235000013399 edible fruits Nutrition 0.000 abstract 1
- 239000001947 glycyrrhiza glabra rhizome/root Substances 0.000 abstract 1
- 239000001645 levisticum officinale Substances 0.000 abstract 1
- 239000002023 wood Substances 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 11
- 201000010099 disease Diseases 0.000 description 10
- 230000001737 promoting effect Effects 0.000 description 6
- 230000017531 blood circulation Effects 0.000 description 4
- 208000004880 Polyuria Diseases 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 230000035619 diuresis Effects 0.000 description 3
- 206010000077 Abdominal mass Diseases 0.000 description 2
- 206010030113 Oedema Diseases 0.000 description 2
- 230000004087 circulation Effects 0.000 description 2
- 230000002526 effect on cardiovascular system Effects 0.000 description 2
- 230000001861 immunosuppressant effect Effects 0.000 description 2
- 230000001939 inductive effect Effects 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000003053 toxin Substances 0.000 description 2
- 208000007271 Substance Withdrawal Syndrome Diseases 0.000 description 1
- 230000009285 allergic inflammation Effects 0.000 description 1
- 230000002804 anti-anaphylactic effect Effects 0.000 description 1
- 230000001363 autoimmune Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 229940124579 cold medicine Drugs 0.000 description 1
- 230000006735 deficit Effects 0.000 description 1
- 239000002934 diuretic Substances 0.000 description 1
- 230000001882 diuretic effect Effects 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 230000005714 functional activity Effects 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 230000001506 immunosuppresive effect Effects 0.000 description 1
- 229960003444 immunosuppressant agent Drugs 0.000 description 1
- 239000003018 immunosuppressive agent Substances 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- JTJMJGYZQZDUJJ-UHFFFAOYSA-N phencyclidine Chemical compound C1CCCCN1C1(C=2C=CC=CC=2)CCCCC1 JTJMJGYZQZDUJJ-UHFFFAOYSA-N 0.000 description 1
- 229950010883 phencyclidine Drugs 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 206010040882 skin lesion Diseases 0.000 description 1
- 231100000444 skin lesion Toxicity 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 210000001113 umbilicus Anatomy 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a formula for a systemic lupus erythematosus treatment drug. The formula comprises 10 g of coptis chinensis, 20 g of baikal skullcap root, 15 g of Chinese thorowax root, 10 g of amur corktree bark, 10 g of rheum, 20 g of cape jasmine, 15 g of chrysanthemum, 15 g of szechwan lovage rhizome, 15 g of weeping forsythia fruit, 20 g of kakuda figwort root, 15 g of salvia miltiorrhiza, 30 g of milkvetch root, 15 g of immature bitter orange, 15 g of licorice root, 20 g of rehmannia dride rhizome, 20 g of largehead atractylodes rhizome, 15 g of sappsn wood, 30 g of turtle shell, 30 g of common motherwort herb, 20 g of periostracum cicadae, 20 g of white peony root, 10 g of Chinese ephedra herb, 10 g of agaric, and 15 g of tuckahoe, wherein the drugs are mixed and crushed into 80-100 mesh powder according to a certain ratio, the powder is prepared into pills with a mass of 10 g, people takes 2 pills each time and takes the pills for three times each day, a treatment course is one month, and a good treatment effect can be provided after two treatment course are performed.
Description
Affiliated technical field
The present invention relates to a kind of medicament composing prescription of systemic lupus erythematosus disease, particularly a kind of medicament composing prescription that utilizes Chinese herbal treatment systemic lupus erythematosus (sle) disease.
Background technology
Systemic lupus erythematosus (sle) is similar to the YIN YANG toxin syndrome of motherland's medical science, and its pathogenesis is damp and hot fire-toxin, and its heresy is filled the air three warmers, up and down inside and outside; Invade the part of the body cavity above the diaphragm housing the heart and lungs, main manifestations is burning hot heresy; In the infringement, the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels, main manifestations is damp and hot heresy, modern medicine is thought, the systemic lupus erythematosus (sle) disease is that a kind of autoimmune immunocomplex is sick, often involve whole body a plurality of organs, particularly skin and kidney, the systemic lupus erythematosus (sle) disease does not have preferably Therapeutic Method at present.
Summary of the invention
For systemic lupus erythematosus is sick effectively, the invention provides this sick medicament composing prescription of a kind of very effective treatment.This invention for the plan method for the treatment of of systemic lupus erythematosus (sle) disease is: heat-clearing and toxic substances removing, and blood circulation promoting and blood stasis dispelling, inducing diuresis and reducing edema.
Its prescription is (in grams): Rhizoma Coptidis 10, Radix Scutellariae 20, Radix Bupleuri 15, Cortex Phellodendri 10, Radix Et Rhizoma Rhei 10, Fructus Gardeniae 20, Flos Chrysanthemi 15, Rhizoma Chuanxiong 15, Fructus Forsythiae 15, Radix Scrophulariae 20, Radix Salviae Miltiorrhizae 15, the Radix Astragali 30, Fructus Aurantii Immaturus 15, Radix Glycyrrhizae 15, the Radix Rehmanniae 20, the Rhizoma Atractylodis Macrocephalae 20, Lignum Sappan 15, Carapax Trionycis 30, Herba Leonuri 30, Periostracum Cicadae 20, the Radix Paeoniae Alba 20, Herba Ephedrae 10, Polyporus 10, Poria 15.
Said medicine is mixed in proportion is ground into 80--100 purpose powder, make the pills of 10 grams, each 2 balls, every day 3 times, be a course for the treatment of January, takes two courses for the treatment of, can receive preferably curative effect.
In the side: Radix Scutellariae, Rhizoma Coptidis, Cortex Phellodendri, Fructus Gardeniae, Radix Glycyrrhizae have the effect of clearing away heat-damp and promoting diuresis, in addition, and according to modern study, Fructus Gardeniae, Radix Glycyrrhizae have immunosuppressive action, and Radix Scutellariae has the release that suppresses the allergic inflammation medium, and the Radix Et Rhizoma Rhei bitter cold is rushed down lower, join the Fructus Aurantii Immaturus circulation of qi promoting painful abdominal mass that disappears, damp and hot heresy is separated from stool; Flos Chrysanthemi, Fructus Forsythiae, Radix Scrophulariae all have the effect of Chinese Medicine, can treat the disease of throat, and Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae blood circulation promoting and blood stasis dispelling according to modern study, have the effect of expansion cardiovascular and cerebrovascular vessel, thus the disease at treatment cardiovascular and cerebrovascular vessel position; The Radix Rehmanniae, the Radix Paeoniae Alba, Carapax Trionycis phencyclidine can be prevented the fraud of the impairment of YIN of bitter and cold medicines and drug for invigorating blood circulation and eliminating stasis, the Radix Astragali, Rhizoma Atractylodis Macrocephalae air making-up and spleen enlivening diuretic, the Fructus Aurantii Immaturus circulation of qi promoting painful abdominal mass that disappears, Herba Ephedrae lung qi dispersing harmonizing the functional activities of vital QI, and the Lignum Sappan blood circulation promoting and blood stasis dispelling has the immunosuppressant effect according to modern study.Herba Leonuri, Polyporus, Poria all have the effect of inducing diuresis to remove edema, and the Periostracum Cicadae expelling wind and dampness has immunosuppressant and antianaphylactic effect according to modern study.
This beneficial effect of the invention is: utilize the Chinese herbal medicine of motherland's traditional medicine to carry out reasonable compatibility, treatment cost is lower, and side effect is less, and therapeutic effect is remarkable.
The specific embodiment
The effectiveness of said medicine now is described with 24 routine patients of clinical observation treatment.24 routine patients revise diagnostic criteria according to Americanism damp disease association in 1997 fully, among the patient, man's 3 examples, woman's 21 examples, the shortest person of the course of disease is 2 months, elder is 1 year (the medicine factor that eliminating is associated with the patient of Other diseases and affects the treatment and observe), the patient is by 2 balls, and 3 times on the one taking method is taken 2 courses for the treatment of, the result is according to observations: light-duty (take skin lesion as main) 18 routine patients, cure again recurrence, heavy (also involving other organ-tissue except skin) 6 routine patient's symptoms alleviate to some extent, and rear 6 routine patients take this medicine stable disease after 2 courses for the treatment of again, but can not drug withdrawal, need lifelong after treatment.
Claims (1)
1. the pharmaceutical composition of a systemic lupus erythematosus, it is characterized in that: in grams, Rhizoma Coptidis 10, Radix Scutellariae 20, Radix Bupleuri 15, Cortex Phellodendri 10, Radix Et Rhizoma Rhei 10, Fructus Gardeniae 20, Flos Chrysanthemi 15, Rhizoma Chuanxiong 15, Fructus Forsythiae 15, Radix Scrophulariae 20, Radix Salviae Miltiorrhizae 15, the Radix Astragali 30, Fructus Aurantii Immaturus 15, Radix Glycyrrhizae 15, the Radix Rehmanniae 20, the Rhizoma Atractylodis Macrocephalae 20, Lignum Sappan 15, Carapax Trionycis 30, Herba Leonuri 30, Periostracum Cicadae 20, the Radix Paeoniae Alba 20, Herba Ephedrae 10, Polyporus 10, Poria 15.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011102501082A CN103006877B (en) | 2011-08-18 | 2011-08-18 | Formula for systemic lupus erythematosus treatment drug |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011102501082A CN103006877B (en) | 2011-08-18 | 2011-08-18 | Formula for systemic lupus erythematosus treatment drug |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103006877A CN103006877A (en) | 2013-04-03 |
| CN103006877B true CN103006877B (en) | 2013-10-30 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011102501082A Active CN103006877B (en) | 2011-08-18 | 2011-08-18 | Formula for systemic lupus erythematosus treatment drug |
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| Country | Link |
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| CN (1) | CN103006877B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103933383A (en) * | 2014-03-20 | 2014-07-23 | 毛杰 | Traditional Chinese medicine for treating systemic lupus erythermatosus |
| CN107320613A (en) * | 2017-07-14 | 2017-11-07 | 高学哲 | A kind of systemic lupus erythematosus powder and preparation method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1088788A (en) * | 1992-12-26 | 1994-07-06 | 史宝印 | A kind of lupus for the treatment of lupus erythematosus is loose and compound method |
| CN1422643A (en) * | 2001-12-06 | 2003-06-11 | 高大海 | Oral pill for treating lupus erythematosus |
| CN1488372A (en) * | 2002-10-09 | 2004-04-14 | 赵洪起 | Chinese medicine formual for treating heptitis |
| CN101637585A (en) * | 2009-08-20 | 2010-02-03 | 卢速江 | Chinese herbal preparation for treating posirasis and preparation method thereof |
-
2011
- 2011-08-18 CN CN2011102501082A patent/CN103006877B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1088788A (en) * | 1992-12-26 | 1994-07-06 | 史宝印 | A kind of lupus for the treatment of lupus erythematosus is loose and compound method |
| CN1422643A (en) * | 2001-12-06 | 2003-06-11 | 高大海 | Oral pill for treating lupus erythematosus |
| CN1488372A (en) * | 2002-10-09 | 2004-04-14 | 赵洪起 | Chinese medicine formual for treating heptitis |
| CN101637585A (en) * | 2009-08-20 | 2010-02-03 | 卢速江 | Chinese herbal preparation for treating posirasis and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 尚志华，等.浅述系统性红斑狼疮中药临床的几个问题.《光明中医》.2003,第18卷(第109期),第52-54页. * |
| 范丽英,等.皮肤红斑狼疮中医药治疗现状.《中国中西医结合皮肤性病学杂志》.2008,第7卷(第4期),第260-263页. * |
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| Publication number | Publication date |
|---|---|
| CN103006877A (en) | 2013-04-03 |
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| C14 | Grant of patent or utility model | ||
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| TR01 | Transfer of patent right |
Effective date of registration: 20210319 Address after: No.42-1, sangyuan Road, Licheng District, Jinan City, Shandong Province, 250100 Patentee after: Liu Jinbo Address before: 734200 community 9, kangzhai village, Xinhua Township, Linze County, Gansu Province Patentee before: Zhang Zhitong |
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| TR01 | Transfer of patent right | ||
| DD01 | Delivery of document by public notice | ||
| DD01 | Delivery of document by public notice |
Addressee: Liu Jinbo Document name: Notification of eligibility |
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| DD01 | Delivery of document by public notice | ||
| DD01 | Delivery of document by public notice |
Addressee: Liu Jinbo Document name: Notification of eligibility |
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| TR01 | Transfer of patent right | ||
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Effective date of registration: 20210520 Address after: 650000 Room 501, Unit 1, Building 162 Yongan Road, Taihe Street Office, Guandu District, Kunming City, Yunnan Province Patentee after: Zhang Ruihao Address before: No.42-1, sangyuan Road, Licheng District, Jinan City, Shandong Province, 250100 Patentee before: Liu Jinbo |