CN103330760A - Medicament used for treating allergic purpura - Google Patents
Medicament used for treating allergic purpura Download PDFInfo
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Abstract
The invention discloses a medicament used for treating allergic purpura. The medicament is prepared from gen-seng, largehead atractylodes rhizome, radix astragali, fructus jujubae, Chinese angelica, radix glycyrrhizae and longan according to a certain weight ratio. The medicament can be made into any common oral administration preparation. The medicament has functions of tonifying qi and spleen, nourishing blood and promoting blood circulation, cooling blood and removing toxic and regulating immunity. The medicament can be used for treating the allergic purpura with advantages of rapid effect, high cure rate and no recurrence.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of anaphylactoid purpura and preparation method thereof.
Background technology
Anaphylactoid purpura (Allergic Purpura) claims schonlein-Henoch purpura or Henoch-Sch nlein syndrome again, it is common blood capillary allergic disease, main pathological basis is Capillaritis widely, hemorrhage with skin purpura, gastrointestinal mucosal, symptom such as joint swelling and pain and nephritis is main clinical manifestation, small number of patients is also with vasodilation, and contact allergy is former again can show effect repeatedly for part patient.The degree that kidney is got involved and to lapse to be the key factor that determines prognosis.Anaphylactoid purpura can betide any age, and for seeing, with preschool and school age's hair of children patient is many, one-year-old rare with interior baby, the women is more than male's (ratio is about 3:1) especially more with child and teenager.Western medical treatment is particular about symptomatic treatment, comprises that finding out anaphylactogen is as possible also avoided; Use antihistamine drug such as diphenhydramine, promethazine, buclizine, chlorphenamine etc. and glucocorticoid etc.Therapeutic effect is not ideal, and patient causes a lot of side effect after using hormone, and relapse rate is high.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind for the treatment of both the principal and secondary aspects of a disease at the deficiency of above-mentioned treatment anaphylactoid purpura, strong drug action and Chinese prescription of not recurring and preparation method thereof, especially a kind of medicine for the treatment of anaphylactoid purpura and preparation method thereof.
The consumption of each component of medicine of the present invention draws through groping in a large number to sum up through the inventor, and each amounts of components all has better curative effect in the following weight scope:
Radix Ginseng 5-15 gram, Rhizoma Atractylodis Macrocephalae 10-30 gram, Radix Astragali 10-30 gram, Fructus Jujubae 10-30 gram, Radix Angelicae Sinensis 10-20 gram, Radix Glycyrrhizae 5-10 gram, first meat 10-30 gram, Flos Lonicerae 5-15 gram.
Be preferably: Radix Ginseng 10 grams, the Rhizoma Atractylodis Macrocephalae 20 grams, the Radix Astragali 20 grams, Fructus Jujubae 15 grams, Radix Angelicae Sinensis 15 grams, Radix Glycyrrhizae 6 grams, first meat 15 grams, Flos Lonicerae 10 grams.
Each amounts of components of medicine of the present invention can also be:
Radix Ginseng 5-15 gram, Rhizoma Atractylodis Macrocephalae 10-30 gram, Radix Astragali 10-30 gram, Fructus Jujubae 10-30 gram, Radix Angelicae Sinensis 10-20 gram, Radix Glycyrrhizae 5-10 gram, first meat 10-30 gram, Flos Lonicerae 5-15 gram, Poria 10-30 gram, Cornu Bubali 10-30 gram, Herba Schizonepetae 10-20 gram, Semen Ziziphi Spinosae 10-30 gram, Radix Rehmanniae 10-30 gram.
Be preferably: Radix Ginseng 15 grams, the Rhizoma Atractylodis Macrocephalae 20 grams, the Radix Astragali 20 grams, Fructus Jujubae 15 grams, Radix Angelicae Sinensis 15 grams, Radix Glycyrrhizae 6 grams, first meat 20 grams, Flos Lonicerae 10 grams, Poria 20 grams, Cornu Bubali 20 grams, Herba Schizonepetae 15 grams, Semen Ziziphi Spinosae 20 grams, the Radix Rehmanniae 20 grams.
The medicine of the present invention further consumption of each component is:
Radix Ginseng 5-15 gram, Rhizoma Atractylodis Macrocephalae 10-30 gram, Radix Astragali 10-30 gram, Fructus Jujubae 10-30 gram, Radix Angelicae Sinensis 10-20 gram, Radix Glycyrrhizae 5-10 gram, the meat 10-30 of unit gram, Flos Lonicerae 5-15 gram, Poria 10-30 gram, Cornu Bubali 10-30 gram, Herba Schizonepetae 10-20 gram, Semen Ziziphi Spinosae 10-30 gram, Radix Rehmanniae 10-30 gram, Radix Aucklandiae 10-20 gram, Rhizoma Zingiberis Recens 2-20 gram, Radix Notoginseng 5-20 gram, Radix Polygalae 5-20 gram, chitosan 10-30 gram.
Be preferably: Radix Ginseng 10 grams, the Rhizoma Atractylodis Macrocephalae 20 grams, the Radix Astragali 20 grams, Fructus Jujubae 15 grams, Radix Angelicae Sinensis 15 grams, Radix Glycyrrhizae 6 grams, unit's meat 15 grams, Flos Lonicerae 10 grams, Poria 20 grams, Cornu Bubali 20 grams, Herba Schizonepetae 15 grams, Semen Ziziphi Spinosae 20 grams, the Radix Rehmanniae 20 grams, the Radix Aucklandiae 15 grams, Rhizoma Zingiberis Recens 10 grams, Radix Notoginseng 10 grams, Radix Polygalae 10 grams, chitosan 20 grams.
Medicament selection Radix Ginseng of the present invention, the Rhizoma Atractylodis Macrocephalae, the Radix Astragali, Fructus Jujubae, Radix Angelicae Sinensis, Flos Lonicerae, first meat are as our monarch drug, and all medicines organically combine the effect of playing benefiting qi and nourishing blood altogether.Wherein select for use Radix Ginseng to be because its property is flat, sweet in the mouth, little hardship, tepor is returned spleen, lung, heart channel, and strongly invigorating primordial QI is arranged, and multiple arteries and veins takes off the effect of invigorating the spleen to benefit the lung admittedly.Drug main of the present invention will be used its strongly invigorating primordial QI, and the effect that multiple arteries and veins takes off admittedly for patient's air making-up and spleen enlivening, refreshes.Select the Rhizoma Atractylodis Macrocephalae for use, because of its hardship, sweet, temperature.Return spleen, stomach warp, have the effect of air making-up and spleen enlivening, dampness diuretic.Select the Radix Astragali for use, because of its sweet in the mouth, slightly warm in nature is returned liver, spleen, lung, kidney channel.There are benefiting QI for strengthening the superficies, arresting sweating to take off, hold in the palm the effect of skin ulcer granulation promoting, inducing diuresis to remove edema admittedly.Ni Zhumo: " arresting sweating is defended in the Radix Astragali, tonifying the lung spleen invigorating in fact, and the medicine of wind dispelling fortune poison also.So the people of yang deficiency, spontaneous perspiration frequently, be exterior deficiency and interspaces of skin and muscles being loose also, the Radix Astragali can be defended and arresting sweating in fact; The card of typhoid fever, row is delivered and evil no sweating, be interior deficiency and in the healthy energy weary also, the Radix Astragali can help Tianjin to help antiperspirant; The disease of harmful wind, partially invasion of vessels and brothers are with the person, and the Radix Astragali can flourish muscles and bones; The card of carbuncle and ulcer, the pus and blood internal ulceration, deficiency of YANG QI is not held back the person, and the Radix Astragali can granulation promoting meat, and the erosion of vulva can not rise and send out again, deficiency of YANG QI and person more, the Radix Astragali can granulation promoting meat." select from " book on Chinese herbal medicine converge with speech ".The effect of the existing QI invigorating of the Radix Astragali can be treated the situation that purpura appears in patient skin, muscle-growing and detumescence again.Select Fructus Jujubae for use, sweet because of its property, temperature is returned spleen, stomach warp.The Chinese medicine theory thinks that Fructus Jujubae has the effect of tonify deficiency QI invigorating, nourishing blood to tranquillize the mind, invigorating the spleen and regulating the stomach, and Fructus Jujubae has better curative effect to diseases such as chronic hepatitis, liver cirrhosis, anemia, anaphylactoid purpura.The cyclic adenosine monophosphate that Fructus Jujubae contains is the essential composition of human body cell energy metabolism, can muscle strength reinforcing, allaying tiredness, accelerate patient's rehabilitation.Medicament selection Radix Angelicae Sinensis of the present invention, warm in nature because of it, sweet in the mouth, suffering are returned liver, the heart, spleen channel.The effect that having enriches blood invigorates blood circulation, the symptom of digestive tract of elimination patient asthenia cold abdominalgia.Select Radix Glycyrrhizae, because of the Radix Glycyrrhizae sweet in the mouth, property is flat, and is nontoxic.Treating disorders in five ZANG-organs six internal organs cold and heat pathogen, hard muscles and bones, longue meat, times strength, detoxifcation.Give birth to and use pathogenic fire purging heat, the ripe usefulness exterior cold of loosing, go pharyngalgia, remove pathogenic heat, delay healthy energy, yin nourishing blood, tonifying the spleen and stomach, lung moistening.Radix Glycyrrhizae energy invigorating the spleen and replenishing QI, relieving cough and moistening lung, but emergency detoxifcation again, the above-mentioned all medicines that are in harmonious proportion reach better therapeutic.Unit's meat claims Arillus Longan again, and its sweet in the mouth is warm in nature, GUIXIN, spleen channel.Cure mainly dirty pathogen, control anorexia, inappetence, have benefiting qi and nourishing blood, appetite promoting and the spleen strengthening, the effect of complement void.
Medicament selection Poria of the present invention, Cornu Bubali, Herba Schizonepetae, Semen Ziziphi Spinosae, the Radix Rehmanniae carry out compatibility, are our ministerial drug, have the effect of promoting blood circulation and cooling blood, heat-clearing and toxic substances removing, and through internal organs are removed the gas of what corruption, and detumescencing diuresis alleviates the symptom of patients with anaphylactoid purpura arthroncus.Wherein Poria is flat, flavour of a drug: sweet, light, GUIXIN, spleen channel have mind calming, calm the nerves, the effect of detumescencing diuresis.The Cornu Bubali hardship is salty, and is cold, goes into the heart, liver, spleen, stomach four warps.Because Cornu rhinocerotis is comparatively famous and precious, so traditional Chinese medical science Cornu Bubali commonly used replaces, it has heat clearing away, removing heat from blood, and arresting convulsion, the effect of detoxifcation, Cornu Bubali and Radix Rehmanniae compatibility have the special effect of nourishing YIN and clearing away heat, removing pathogenic heat from blood and toxic substance from the body among the we.Herba Schizonepetae acrid in the mouth, little hardship, property is little wet, goes into lung, Liver Channel.Has the diffusing wind that induces sweat, rash, the skin ulcer that disappears, the effect of hemostasis, through patient's skin space between skin and muscles, the focus of releasing patient skin petechia ecchymosis.Medicament selection Semen Ziziphi Spinosae of the present invention, because of the flat sweet in the mouth of its property, GUIXIN, spleen, liver, gallbladder four warps have the effect of mind tranquilizing and the heart calming, nourishing the liver, arresting sweating.Because liver has the function of dispelling toxicity, detoxicating, so liver function normally is the basic of cure diseases.So choice of drug Semen Ziziphi Spinosae of the present invention is assisted all medicines, protect the liver and protect gallbladder, for other each component drug performance drug effect is removed the obstacles.The Radix Rehmanniae also is Radix Rehmanniae, has the effect that clearing away heat and cooling blood, tonifying YIN promote the production of body fluid, and Li Shizhen (1518-1593 A.D.) to the evaluation of Radix Rehmanniae is: " one hundred days of clothes are rosy cheeks, make light of one's life by commiting suicide not old in 3 years ".As seen it has the special effect of YIN nourishing detoxifcation.Flos Lonicerae: sweet, cold lung, stomach, the heart large intestine channel of returning.Effect with heat-clearing and toxic substances removing, dispelling wind and heat pathogens, adjusting immunity, antiinflammatory sterilization.Exactly because the effect that this prescription is selected its good heat-clearing and toxic substances removing of Flos Lonicerae for use and regulated immunity.
Medicine of the present invention also selects Radix Glycyrrhizae, the Radix Aucklandiae, Rhizoma Zingiberis Recens, Radix Notoginseng, Radix Polygalae, chitosan to help, make it medicine as we, and reducing swelling and alleviating pain is in harmonious proportion in the reason, assists monarch drug, ministerial drug performance drug effect, and the focus of going directly is removed old complaint.The wherein Radix Aucklandiae, Rhizoma Zingiberis Recens, Radix Notoginseng, all property of medicine temperature of Radix Polygalae are used for the drug effect between this side's coordinating the actions of various ingredients in a prescription, and the effectiveness of certain medicine is unlikely too in fiercely.Have the effect of regulating the flow of vital energy in transferring, Chang Zuowei QI regulating medicine, qi-activating drug, drugs for dispelling internal cold on the traditional Chinese medical science as the Radix Aucklandiae; Rhizoma Zingiberis Recens, acrid in the mouth, slightly warm in nature is returned lung, spleen, stomach warp, has the effect of separating poison of drug; Radix Notoginseng, sweet in the mouth, little hardship, warm in nature, have antiinflammatory, protect the liver, the analgesic effect, can alleviate the symptom of patient's nephritis and joint swelling and pain; Radix Polygalae, bitter in the mouth, suffering, slightly warm in nature, GUIXIN, kidney, lung meridian, its hot row hardship is let out, and the heap soil or fertilizer over and around the roots that merit is arrogated to oneself promoting flow of QI and blood stagnates and the dissipation carbuncle, with Radix Notoginseng and with alleviating patient's edema symptom.Chitosan
Have unique polymerizing cationically characteristic, gelling and film property, can control drug administration speed, prolong effective therapeutical effect time, also can also have effects such as the stripping of promotion, accelerating wound, promotion absorption in addition with medicine to specific position target administration.
" " if status of patient allows, also can add Stigma Croci 1-10 gram, Herba Saussureae Involueratae 2-5 gram in the medicine of the present invention.Because of Stigma Croci sweet in the mouth, little hardship, cool in nature, have blood circulation promoting and blood stasis dispelling, removing heat from the liver is trained the effect of first body-building.And Herba Saussureae Involueratae has more warming the kidney to activate YANG, and expelling wind and dampness restores menstrual flow and invigorates blood circulation, warms up the special effect through blood stasis dispelling, and it contains rich in protein and aminoacid, can regulate the human body acid-base value effectively, strengthens body immunity and resisting fatigue, has anti-aging effects." " this section do not wanted.Making bottom into?
Pulse condition according to the patient changes us on the basis of power and often select Radix Scrophulariae, Radix Ophiopogonis, Fructus Forsythiae, Folium Bambusae, Radix Salviae Miltiorrhizae, Rhizoma Coptidis to add and subtract, and to adapt to patient's change of illness state, guarantees patient's curative effect.
More than the cooperation of all medicines, reach qi and blood tonifying, removing pathogenic heat from blood and toxic substance from the body, the warming the interior circulation of qi promoting, anti-inflammatory analgesic, the effect of dissipating blood stasis for subsidence of swelling, enhancing immunity, all medicines are made a concerted effort, and cut the pass and directly go into, medicine is concentrated one's efforts grand, the through focus of drug effect performance is finally eliminated persistent ailment and is no longer recurred.
The specific embodiment
A kind of medicine for the treatment of anaphylactoid purpura, form (weight meter) by following each component drug:
Radix Ginseng 5-15 gram, Rhizoma Atractylodis Macrocephalae 10-30 gram, Radix Astragali 10-30 gram, Fructus Jujubae 10-30 gram, Radix Angelicae Sinensis 10-20 gram, Radix Glycyrrhizae 5-10 gram, the meat 10-30 of unit gram, Flos Lonicerae 5-15 gram, Poria 10-30 gram, Cornu Bubali 10-30 gram, Herba Schizonepetae 10-20 gram, Semen Ziziphi Spinosae 10-30 gram, Radix Rehmanniae 10-30 gram, Radix Aucklandiae 10-20 gram, Rhizoma Zingiberis Recens 2-20 gram, Radix Notoginseng 5-20 gram, Radix Polygalae 5-20 gram, chitosan 10-30 gram.
Be preferably: Radix Ginseng 10 grams, the Rhizoma Atractylodis Macrocephalae 20 grams, the Radix Astragali 20 grams, Fructus Jujubae 15 grams, Radix Angelicae Sinensis 15 grams, Radix Glycyrrhizae 6 grams, unit's meat 15 grams, Flos Lonicerae 10 grams, Poria 20 grams, Cornu Bubali 20 grams, Herba Schizonepetae 15 grams, Semen Ziziphi Spinosae 20 grams, the Radix Rehmanniae 20 grams, the Radix Aucklandiae 15 grams, Rhizoma Zingiberis Recens 10 grams, Radix Notoginseng 10 grams, Radix Polygalae 10 grams, chitosan 25 grams.
The preparation method of medicine of the present invention may further comprise the steps:
A) take by weighing each crude drug Radix Ginseng, the Rhizoma Atractylodis Macrocephalae, the Radix Astragali, Fructus Jujubae, Radix Angelicae Sinensis, Radix Glycyrrhizae, Flos Lonicerae, Poria, Cornu Bubali, Herba Schizonepetae, Semen Ziziphi Spinosae, first meat, the Radix Rehmanniae, the Radix Aucklandiae, Rhizoma Zingiberis Recens, Radix Notoginseng and Radix Polygalae;
B) each crude drug with described weight proportion decocts with water twice, and each amount of water was not advisable to have powder, merged decocting liquid twice, is condensed into proportion after the filtration and is 1.35 extractum, 40-50 ℃ dry down, make dry extract;
C) dry extract is added the chitosan of described weight proportion, grind to form 130 purpose fine powders, just be prepared into the active component of medicine of the present invention.
D) Chinese medicines such as the Radix Scrophulariae according to patient's pulse condition needs plus-minuss of described weight proportion, Radix Ophiopogonis, Radix Salviae Miltiorrhizae, Rhizoma Coptidis are directly added in the step b) decoct.
E) active component that step c) is made is made granular electuary, or mixes with tablet adjuvant commonly used, and tabletting is made conventional Chinese patent medicine for oral administration.It is for oral administration to make honeyed pill.
F) wherein in step b), medicine is decocted with water when extracting, add 8 times of amounts of water for the first time, decocted 1.5 hours, add 6 times of amounts of water for the second time, decocted 1 hour.
G) described weight proportion is directly added in the step b) according to Chinese medicines such as the Radix Scrophulariae of patient's pulse condition needs plus-minuss, Radix Ophiopogonis, Radix Salviae Miltiorrhizae, Rhizoma Coptidis decoct.
When using clinically, clothes down also can be with b after the dry extract that said process can be made added the water mixing of 1:2) directly clothes are down for twice boils in the process the decocting liquid chitosan that adds described weight proportion.Can also make tablet, honeyed pill so that the patient takes.Medicine instant effect cure rate of the present invention is high and do not recur, and the anaphylactoid purpura that the various causes of disease are caused all has significant curative effect.Do not use the patient of hormone therapy to use medicine 20---60 of the present invention to pay recovery from illness, used the patient treatment cycle 2 of hormone therapy not wait to 7 months.The patient used the more long treatment cycle of this Chinese medicine preparation of then using of the time of hormone therapy more long.By statistics, during 2007 to 2012, cure patients with anaphylactoid purpura 784 examples altogether, women's 588 examples wherein, male's 196 examples, women's morbidity is higher than the male, and wherein the oldest person is 75 years old, and reckling 5 years old is in the majority with teenager and child.Treatment time 2 months with interior person's 548 examples, 230 examples during 2 months to 6 months, person's 6 examples more than 6 months are cured all phenomenons of recurrence more not of patient.
Symptom and sign:
The skin purpura comes across around the joint of the lower extremity and buttocks more, and purpura is symmetrical distribution, occurs in batches, differs in size, shade differs, gastrointestinal mucosal is hemorrhage, joint swelling and pain and nephritis, child patient is many with albuminuria, hematuria, and small number of patients is also with vasodilation.
Therapeutic Method:
When (1) taking drug powder of the present invention, get the 10-20 gram when taking every day 3 times, boiled water is taken after mixing it with water at every turn.
When (2) taking drug powder of the present invention, can make tea bag formula packing every day 3 times, get one to two bag at every turn, boiled water boils bubble.
When (3) taking Chinese medicinal tablet of the present invention, every day 3 times, each 4-8 sheet when taking (being equivalent to raw material 10-20 gram), warm water delivery service.
When (4) taking honeyed pill of the present invention, every day 3 times, each 10-20 balls when taking (being equivalent to raw material 10-20 gram), warm water delivery service.
Above-mentioned Chinese medicine formula 7 days was a course for the treatment of, can take continuously, age and body constitution difference according to everyone when taking take the circumstances into consideration to add and subtract medication, because the growth at age, corresponding the weakening of old people's restoring force more than 60 years old, corresponding prolongation medicine time generally needs 5-6 the course for the treatment of, person between twenty and fifty and general 3-4 below 60 years old get final product a course for the treatment of, and child below 10 years old generally needs 4-5 the recovery from illness course for the treatment of.
Judgment criteria as a result: the illness symptom complete obiteration, and tracing observation runs into identical anaphylactogen in 2 years and no longer recurs.
Therapeutic outcome: this is organized among the 177 routine case patients, 177 examples of fully recovering, cure rate 100%.
Concrete age bracket and sex combination healing situation see the following form (unit: example):
We judge the order of severity of the state of an illness according to patient's kidney degree of getting involved, and make following evaluation criteria:
Severe: the patient is except below the conventional symptom that anaphylactoid purpura is arranged, and the kidney degree of getting involved is serious, the situation of albuminuria, hematuria and pyelonephritis occurred;
Moderate: the patient only shows the skin purpura, gastrointestinal mucosal is hemorrhage, and the symptom that kidney is got involved does not appear in symptoms such as joint swelling and pain;
Slightly: petechia appears in patient skin surface, comes across around the joint of the lower extremity and buttocks more, and purpura is symmetrical distribution, occurs in batches, differs in size, shade differs, and does not have other symptom.
According to the order of severity and the corresponding treatment time of conditions of patients, we formulated following form (unit: example):
Below be some cases:
Case 1: the king so-and-so, the woman, 7 years old, live the Wulian County, Shandong Province, suffer from the anaphylaxis purpura in March, 2009, use this Chinese medicine preparation 30 days (30 pairs) recovery from illness, so far the recurrence.
Case 2: Wang's woman, 9 years old, live the Wulian County, Shandong Province, suffer from anaphylactoid purpura in April, 2009, once went to Affiliated Hospital of Qingdao Medical Inst, BJ Children's Hospital to treat, through making some inquiries about this cover Chinese medicine preparation 45 days (45 pairs) back recovery from illness of using us in August, 2009, recurred so far.
Case 3: Hu, the woman, 56 years old, live the Wulian County, Shandong Province in Li Zhen, suffer from anaphylactoid purpura in June, 2007, and fully recovering in 20 days (20 pairs) back to use this Chinese medicine preparation, so far recurrence.
Case 4: Yuan so-and-so, the woman 5 years old, lives Wang Hu town, Wulian County, Shandong Province.Suffer from anaphylactoid purpura in July, 2008, once goes to People's Armed Police hospital general, Beijing to treat, and used hormone.Use this Chinese medicine preparation 210 days (210 pairs), last recovery from illness in seven months, so far not recurrence.
Case 5: what so-and-so, the woman, 10 years old, live Gao Ze town, Wulian County, Shandong Province, suffer from anaphylactoid purpura in May, 2009, and 30 days (30 pairs) recovery from illness of taking this Chinese medicine preparation is recurred so far.
Case 6: Lee, the man, 12 years old, live Xu Meng town, Wulian County, Shandong Province journey, suffer from anaphylactoid purpura in April, 2008, and 40 days (40 pairs) fully recover to take this Chinese medicine preparation, so far recurrence.
Case 7: Zheng, the woman, 13 years old, to live Wulian County, Shandong Province flood and coagulate the town, suffer from anaphylactoid purpura in April, 2010, takes recovery from illness, recurrence so far behind 50 pairs of this Chinese medicine preparation.
Case 8: the king so-and-so, the man, 14 years old, live in the Wulian County, Shandong Province to the town, suffer from anaphylactoid purpura in May, 2010, takes recovery from illness, recurrence so far behind 45 pairs of this Chinese medicine preparation.
Case 9: so-and-so woman of Lee, 13 years old, live Xu Meng town, Wulian County, Shandong Province, in JIUYUE, 2009 is suffered from anaphylactoid purpura, takes recovery from illness, recurrence so far behind 55 pairs of this Chinese medicine preparation.
Case 10 what certain, the woman, 12 years old, live Gao Ze town, Wulian County, Shandong Province, suffer from anaphylactoid purpura in November, 2009, takes recovery from illness behind 60 pairs of this Chinese medicine preparation, recurs so far.
Case 11: Liu so-and-so, the woman, 35 years old, live Shi Chang township, Wulian County, Shandong Province, in December, 2010 is suffered from anaphylactoid purpura, takes recovery from illness, recurrence so far behind 60 pairs of this Chinese medicine preparation.
Claims (11)
1. a medicine for the treatment of anaphylactoid purpura is characterized in that it mainly is by Radix Ginseng 5-15 gram, Rhizoma Atractylodis Macrocephalae 10-30 gram, Radix Astragali 10-30 gram, Fructus Jujubae 10-30 gram, Radix Angelicae Sinensis 10-20 gram, Radix Glycyrrhizae 5-10 gram, first meat 10-30 gram, Flos Lonicerae 5-15 gram.
2. medicine according to claim 1, wherein the consumption of each crude drug is: Radix Ginseng 10 grams, the Rhizoma Atractylodis Macrocephalae 20 grams, the Radix Astragali 20 grams, Fructus Jujubae 15 grams, Radix Angelicae Sinensis 15 grams, Radix Glycyrrhizae 6 grams, first meat 15 grams, Flos Lonicerae 10 grams.
3. the preparation method of claim 1 or 2 described medicines, it may further comprise the steps:
A) take by weighing each crude drug Radix Ginseng, the Rhizoma Atractylodis Macrocephalae, the Radix Astragali, Fructus Jujubae, Radix Angelicae Sinensis, Radix Glycyrrhizae, first meat, Flos Lonicerae, standby;
B) each crude drug with described weight proportion decocts with water twice, and each amount of water was not advisable to have powder, merged decocting liquid twice, is condensed into proportion after the filtration and is 1.35 extractum, 40-50 ℃ dry down, make dry extract;
C) dry extract is ground to form 130 purpose fine powders, just be prepared into the active component of medicine of the present invention.
4. according to the described medicine of claim 1, wherein crude drug also has: Poria 10-30 gram, Cornu Bubali 10-30 gram, Herba Schizonepetae 10-20 gram, Semen Ziziphi Spinosae 10-30 gram, Radix Rehmanniae 10-30 gram.
5. medicine according to claim 4, wherein the consumption of each crude drug is: Radix Ginseng 10 grams, the Rhizoma Atractylodis Macrocephalae 20 grams, the Radix Astragali 20 grams, Fructus Jujubae 15 grams, Radix Angelicae Sinensis 15 grams, Radix Glycyrrhizae 6 grams, first meat 15 grams, Flos Lonicerae 10 grams, Poria 20 grams, Cornu Bubali 20 grams, Herba Schizonepetae 15 grams, Semen Ziziphi Spinosae 20 grams, the Radix Rehmanniae 20 grams.
6. according to the preparation method of claim 4 or 5 described medicines, it may further comprise the steps:
A) take by weighing each crude drug Radix Ginseng, the Rhizoma Atractylodis Macrocephalae, the Radix Astragali, Fructus Jujubae, Radix Angelicae Sinensis, Radix Glycyrrhizae, first meat, Flos Lonicerae, Poria, Cornu Bubali, Herba Schizonepetae, Semen Ziziphi Spinosae and the Radix Rehmanniae;
B) each crude drug with described weight proportion decocts with water twice, and each amount of water was not advisable to have powder, merged decocting liquid twice, is condensed into proportion after the filtration and is 1.35 extractum, 40-50 ℃ dry down, make dry extract;
C) dry extract is ground to form 130 purpose fine powders, just be prepared into the active component of medicine of the present invention.
7. according to the medicine of claim 4, wherein crude drug also has Radix Aucklandiae 10-20 gram, Rhizoma Zingiberis Recens 2-20 gram, Radix Notoginseng 5-20 gram, Radix Polygalae 5-20 gram, chitosan 10-30 gram.
8. medicine according to claim 7, wherein the consumption of each crude drug is Radix Ginseng 10 grams, the Rhizoma Atractylodis Macrocephalae 20 grams, the Radix Astragali 20 grams, Fructus Jujubae 15 grams, Radix Angelicae Sinensis 15 grams, Radix Glycyrrhizae 6 grams, Flos Lonicerae 10 grams, unit's meat 15 grams, Poria 20 grams, Cornu Bubali 20 grams, Herba Schizonepetae 15 grams, Semen Ziziphi Spinosae 20 grams, the Radix Rehmanniae 20 grams, the Radix Aucklandiae 15 grams, Rhizoma Zingiberis Recens 10 grams, Radix Notoginseng 10 grams, Radix Polygalae 10 grams, chitosan 25 grams.
9. according to the preparation method of claim 7 or 8 described medicines, it may further comprise the steps:
A)) take by weighing each crude drug Radix Ginseng, the Rhizoma Atractylodis Macrocephalae, the Radix Astragali, Fructus Jujubae, Radix Angelicae Sinensis, Radix Glycyrrhizae, first meat, Flos Lonicerae, Poria, Cornu Bubali, Herba Schizonepetae, Semen Ziziphi Spinosae, the Radix Rehmanniae, the Radix Aucklandiae, Rhizoma Zingiberis Recens, Radix Notoginseng and Radix Polygalae;
B) each crude drug with described weight proportion decocts with water twice, and each amount of water was not advisable to have powder, merged decocting liquid twice, is condensed into proportion after the filtration and is 1.35 extractum, 40-50 ℃ dry down, make dry extract;
C) dry extract is added the chitosan of described weight proportion, grind to form 130 purpose fine powders, just be prepared into the active component of medicine of the present invention.
10. according to the preparation method of the described medicine of claim 9, wherein the active component that step c) is made is prepared into electuary, can also mix tabletting or make honeyed pill with tablet adjuvant commonly used.
11. according to claim 3,6,9 or 10 described methods, wherein in step b), medicine is decocted with water when extracting, add 8 times of amounts of water for the first time, decocted 1.5 hours, add 6 times of amounts of water for the second time, decocted 1 hour.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105267481A (en) * | 2014-06-25 | 2016-01-27 | 张红伶 | Medicine for treating allergic purpura |
| CN107050165A (en) * | 2017-06-20 | 2017-08-18 | 朱彩玲 | A kind of medicament and its manufacture craft for being used to treat purpura |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105267481A (en) * | 2014-06-25 | 2016-01-27 | 张红伶 | Medicine for treating allergic purpura |
| CN107050165A (en) * | 2017-06-20 | 2017-08-18 | 朱彩玲 | A kind of medicament and its manufacture craft for being used to treat purpura |
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Application publication date: 20131002 |