CN106110033A - A kind of Chinese medicine composition treating atrophic gastritis and preparation method thereof - Google Patents
A kind of Chinese medicine composition treating atrophic gastritis and preparation method thereof Download PDFInfo
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- CN106110033A CN106110033A CN201610653404.XA CN201610653404A CN106110033A CN 106110033 A CN106110033 A CN 106110033A CN 201610653404 A CN201610653404 A CN 201610653404A CN 106110033 A CN106110033 A CN 106110033A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/36—Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/535—Perilla (beefsteak plant)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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Abstract
The invention discloses a kind of Chinese medicine composition treating atrophic gastritis, include following raw material by weight: Radix Pseudostellariae 13, Herba Belladonnae 35, Rhizoma Phragmitis 68, Flos Daturae 13, Poria 8 10, Folium Perillae 68, Semen Persicae 13, Caulis Bambusae In Taenia 35.
Description
Technical field
The present invention relates to application and the preparation field of pharmaceuticals, relate to a kind of Chinese medicine composition treating atrophic gastritis.
Background technology
Stomachache, also known as gastric abscess, refers to pain at the nearly pit of the stomach in upper abdomen gastral cavilty portion, and the traditional Chinese medical science thinks that stomachache is that taste are impaired, QI and blood
The pain in uncomfortable caused gastral cavilty portion, how with diseases caused by exogenous pathogenic factor cold-evil, injury due to diet, feelings will is smooth and the cause of disease such as emptiness of spleen and stomach and draw
Sending out, eating is pungent scorching plus dry weather, and stomach-fire does not drops；The acute gastritis of doctor trained in Western medicine, chronic gastritis, gastric ulcer, duodenum
The above abdominal pains such as ulcer, functional digestive obstacle are cardinal symptom, belong to Chinese medicine atrophic gastritis scope.Treatment at present
The method of atrophic gastritis has Chinese traditional treatment and western medical treatment, western medical treatment typically with amoxicillin+omeprazole+metronidazole,
I.e. triple therapy, antacid infection is main, substantially can only alleviate or release symptom, and long-term taking antibiotic, injure one's stomach
Gas, causes patient's anorexia, malnutrition, and health is weaker.The traditional Chinese medical science is with cold and heat and asthenia and sthenia, coldheat complex, relatively common, but
Ignoring taste prolonged deficiency, long-pending silt is not smooth, and only balance taste negative and positive are not enough.Therefore causing unsatisfactory curative effect, Most patients is anti-
Feedback is only stomachache transference cure, but dietary amount does not increases, and digests and assimilates and do not improved.
Summary of the invention
It is an object of the invention to provide one and treat stomachache, and appetite and the Chinese medicine composition digested and assimilated can be improved.
The present invention is achieved through the following technical solutions:
A kind of Chinese medicine composition treating atrophic gastritis, including the raw material of following weight portion: Radix Pseudostellariae 1-3, Herba Belladonnae
3-5, Rhizoma Phragmitis 6-8, Flos Daturae 1-3, Poria 8-10, Folium Perillae 6-8, Semen Persicae 1-3, Caulis Bambusae In Taenia 3-5.
Preferably, including the raw material of following weight portion: Radix Pseudostellariae 2, Herba Belladonnae 4, Rhizoma Phragmitis 7, Flos Daturae 2, Poria 9, Folium Perillae
7, Semen Persicae 2, Caulis Bambusae In Taenia 4.
The present invention also provides for the preparation method of a kind of Chinese medicine composition treating atrophic gastritis: comprise following process step
Rapid: take the Radix Pseudostellariae of each weight portion, Herba Belladonnae, Rhizoma Phragmitis, Flos Daturae, Poria, Folium Perillae, Semen Persicae, Caulis Bambusae In Taenia by proportion relation；Add 70%
Ethanol soaks 15 minutes at 60～65 DEG C, reflux, extract, 2-3 time, each 1 hour, and 100 mesh filters filter, and obtain extracting solution；Merge
Extracting solution, recovered under reduced pressure in input concentrating under reduced pressure tank, ethanol, to without alcohol taste, obtains concentrated solution；By concentrated solution 70-100 DEG C of spraying
Being dried or dry, be ground into the fine powder of 70-100 mesh, after granulation, Conventional compression or encapsulated, to obtain final product.
Prescription of the present invention is exquisite, each component synergism, analgesia of releiving, and clearing stomach spleen invigorating, desilting helps digestion, insufficiency of the spleen for gastric heat
Person is especially suitable.
Detailed description of the invention
Embodiment 1
(1) Radix Pseudostellariae 1 part, Herba Belladonnae 3 parts, Rhizoma Phragmitis 6 parts, Flos Daturae 1 part, 8 parts of Poria, Folium Perillae 6 parts, 1 part of Semen Persicae, bamboo are taken
Eat 3 parts standby；
(2) adding 70% ethanol to soak 15 minutes at 60 DEG C, reflux, extract, 2 times, each 1 hour, 100 mesh filters filter,
Extracting solution；United extraction liquid, recovered under reduced pressure in input concentrating under reduced pressure tank, ethanol, to without alcohol taste, obtains concentrated solution；By concentrated solution 70
DEG C be spray-dried or dry, be ground into the fine powder of 70 mesh, encapsulated after granulation, specification 0.45g/ grain. each 3 times of morning, noon and afternoon, ante cibum
Take, each 3-5 grain.
Embodiment 2
(1) take Radix Pseudostellariae 3 parts, Herba Belladonnae 5 parts, Rhizoma Phragmitis 8 parts, Flos Daturae 3 parts, 10 parts of Poria, Folium Perillae 8 parts, 3 parts of Semen Persicae,
Caulis Bambusae In Taenia 5 parts is standby；
(2) adding 70% ethanol to soak 15 minutes at 65 DEG C, reflux, extract, 3 times, each 1 hour, 100 mesh filters filter,
Extracting solution；United extraction liquid, recovered under reduced pressure in input concentrating under reduced pressure tank, ethanol, to without alcohol taste, obtains concentrated solution；Concentrated solution is existed
100 DEG C are spray-dried or dry, are ground into the fine powder of 100 mesh, encapsulated after granulation, specification 0.45g/ grain.
Embodiment 3
(1) Radix Pseudostellariae 2 parts, Herba Belladonnae 4 parts, Rhizoma Phragmitis 7 parts, Flos Daturae 2 parts, 9 parts of Poria, Folium Perillae 7 parts, 2 parts of Semen Persicae, bamboo are taken
Eat 4 parts standby；
(2) adding 70% ethanol to soak 15 minutes at 62 DEG C, reflux, extract, 2 times, each 1 hour, 100 mesh filters filter,
Extracting solution；United extraction liquid, recovered under reduced pressure in input concentrating under reduced pressure tank, ethanol, to without alcohol taste, obtains concentrated solution；By concentrated solution 80
DEG C be spray-dried or dry, be ground into the fine powder of 90 mesh, encapsulated after granulation, specification 0.45g/ grain.
Clinical efficacy data
1, the effect observation that has a stomach-ache is treated
1.1 objects: atrophic gastritis observes 1000 people, with gastralgia, hyperchlorhydria and the chronic dietary stagnation of QI, defecate first
Half congealed, belch after hard, stomach has burn feeling.
1.2 medicine compositions: Radix Pseudostellariae 200 grams, Herba Belladonnae 400 grams, Rhizoma Phragmitis 700 grams, Flos Daturae 200 grams, Poria 900
Gram, Folium Perillae 700 grams, 200 grams of Semen Persicae, Caulis Bambusae In Taenia 400 grams.
Said medicine adds 70% ethanol soak 15 minutes at 62 DEG C, reflux, extract, 2 times, each 1 hour, 100 mesh filters
Filter, obtain extracting solution；United extraction liquid, recovered under reduced pressure in input concentrating under reduced pressure tank, ethanol, to without alcohol taste, obtains concentrated solution；By dense
Contracting liquid is spray-dried at 80 DEG C or dries, and is ground into the fine powder of 90 mesh, and encapsulated after granulation, specification 0.45g/ grain, the morning, noon and afternoon are each
Once, bfore meals, each 3-5 grain.
1.3 curative effect judging standards:
Cure: gastralgia and other transference cures, x line, canel barium meal contrast examination or gastroscopy are normal.
Taking a turn for the better: stomachache is alleviated, outbreak reduces, other symptoms alleviate.
Not healing: x line, canel barium meal contrast examination or gastroscopy are the same with premorbid, symptom is without improving and taking a turn for the better.
Treatment stomachache 1000 example effects
After using 30 days, 1000 examples effective 691 examples of stomachache, take a turn for the better 194 examples, invalid 105 examples, obvious effective rate 69%, improvement rate
20%, total effective rate 89%.In use, all user all reflect that appetite improves, appetite increase, and stool form and
Color makes moderate progress.
Claims (3)
1. the Chinese medicine composition treating atrophic gastritis, it is characterised in that include the raw material of following weight portion: Radix Pseudostellariae 1-
3, Herba Belladonnae 3-5, Rhizoma Phragmitis 6-8, Flos Daturae 1-3, Poria 8-10, Folium Perillae 6-8, Semen Persicae 1-3, Caulis Bambusae In Taenia 3-5.
A kind of Chinese medicine composition treating atrophic gastritis the most according to claim 1, it is characterised in that include following heavy
The raw material of amount part: Radix Pseudostellariae 2, Herba Belladonnae 4, Rhizoma Phragmitis 7, Flos Daturae 2, Poria 9, Folium Perillae 7, Semen Persicae 2, Caulis Bambusae In Taenia 4.
The preparation method of a kind of Chinese medicine composition treating atrophic gastritis the most according to claim 1 and 2: its feature exists
In comprising following process steps: take the Radix Pseudostellariae of each weight portion by proportion relation, Herba Belladonnae, Rhizoma Phragmitis, Flos Daturae, Poria, Folium Perillae,
Semen Persicae, Caulis Bambusae In Taenia；Add 70% ethanol to soak 15 minutes at 60～65 DEG C, reflux, extract, 2-3 time, each 1 hour, 100 mesh filter filters
Cross, obtain extracting solution；United extraction liquid, recovered under reduced pressure in input concentrating under reduced pressure tank, ethanol, to without alcohol taste, obtains concentrated solution；To concentrate
Liquid is spray-dried at 70-100 DEG C or dries, and is ground into the fine powder of 70-100 mesh, and after granulation, Conventional compression or encapsulated, to obtain final product.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610653404.XA CN106110033A (en) | 2016-08-10 | 2016-08-10 | A kind of Chinese medicine composition treating atrophic gastritis and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610653404.XA CN106110033A (en) | 2016-08-10 | 2016-08-10 | A kind of Chinese medicine composition treating atrophic gastritis and preparation method thereof |
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| CN106110033A true CN106110033A (en) | 2016-11-16 |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103463311A (en) * | 2013-09-17 | 2013-12-25 | 耿文杰 | Method for preparing center clearing and spleen strengthening pills |
| CN104888118A (en) * | 2015-06-01 | 2015-09-09 | 潘华峰 | Traditional Chinese medicinal composition for treating chronic atrophic gastritis as well as preparation method and application thereof |
-
2016
- 2016-08-10 CN CN201610653404.XA patent/CN106110033A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103463311A (en) * | 2013-09-17 | 2013-12-25 | 耿文杰 | Method for preparing center clearing and spleen strengthening pills |
| CN104888118A (en) * | 2015-06-01 | 2015-09-09 | 潘华峰 | Traditional Chinese medicinal composition for treating chronic atrophic gastritis as well as preparation method and application thereof |
Non-Patent Citations (1)
| Title |
|---|
| 马文军等: "健脾活血清热法治疗慢性萎缩性胃炎60例", 《陕西中医学院学报》 * |
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Application publication date: 20161116 |