CN106138533A - A kind of Chinese medicine composition treating flatulence pain and preparation method thereof - Google Patents
A kind of Chinese medicine composition treating flatulence pain and preparation method thereof Download PDFInfo
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- CN106138533A CN106138533A CN201610651426.2A CN201610651426A CN106138533A CN 106138533 A CN106138533 A CN 106138533A CN 201610651426 A CN201610651426 A CN 201610651426A CN 106138533 A CN106138533 A CN 106138533A
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A—HUMAN NECESSITIES
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
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- A—HUMAN NECESSITIES
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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Abstract
The invention discloses a kind of Chinese medicine composition treating flatulence pain, include following raw material by weight: Radix Panacis Quinquefolii 13, Herba Belladonnae 35, Rhizoma Acori Calami 68, Mentholum 0.1 0.3, Poria 68, Herba Corydalis 8 12, Radix Salviae Miltiorrhizae 13, Cortex Mori 13.
Description
Technical field
The present invention relates to application and the preparation field of pharmaceuticals, relate to a kind of Chinese medicine composition treating flatulence pain.
Background technology
Stomachache, also known as gastric abscess, refers to pain at the nearly pit of the stomach in upper abdomen gastral cavilty portion, and the traditional Chinese medical science thinks that stomachache is that taste are impaired, QI and blood
The pain in uncomfortable caused gastral cavilty portion, how with diseases caused by exogenous pathogenic factor cold-evil, injury due to diet, feelings will is smooth and the cause of disease such as emptiness of spleen and stomach and draw
Sending out, add autumn and winter dry weather, the dry peppery thing of polyphagia, the people suffering from stomachache gets more and more；The acute gastritis of doctor trained in Western medicine, chronic gastritis,
The above abdominal pains such as gastric ulcer, duodenal ulcer, functional digestive obstacle are cardinal symptom, belong to Chinese medicine flatulence pain model
Enclose.At present the method for the treatment of flatulence pain has Chinese traditional treatment and western medical treatment, western medical treatment typically with amoxicillin+omeprazole+
Metronidazole, i.e. triple therapy, antacid infection is main, substantially can only alleviate or release symptom, and long-term taking antibiotic,
Injure one's stomach gas, causes patient's anorexia, malnutrition, and health is weaker.The traditional Chinese medical science, with cold and heat and asthenia and sthenia, coldheat complex, compares
Common, but ignore taste prolonged deficiency, long-pending silt is not smooth, and only balance taste negative and positive are not enough.Therefore unsatisfactory curative effect is caused, great majority
Patient feedback is only stomachache transference cure, but dietary amount does not increases, and digests and assimilates and do not improved.
Summary of the invention
It is an object of the invention to provide one and treat stomachache, and appetite and the Chinese medicine composition digested and assimilated can be improved.
The present invention is achieved through the following technical solutions:
A kind of Chinese medicine composition treating flatulence pain, including the raw material of following weight portion: Radix Panacis Quinquefolii 1-3, Herba Belladonnae 3-5,
Rhizoma Acori Calami 6-8, Mentholum 0.1-0.3, Poria 6-8, Herba Corydalis 8-12, Radix Salviae Miltiorrhizae 1-3, Cortex Mori 1-3.
Preferably, including the raw material of following weight portion: Radix Panacis Quinquefolii 2, Herba Belladonnae 4, Rhizoma Acori Calami 7, Mentholum 0.2, Poria 7,
Herba Corydalis 10, Radix Salviae Miltiorrhizae 2, Cortex Mori 2.
The present invention also provides for the preparation method of a kind of Chinese medicine composition treating flatulence pain: comprise following process steps: press
Proportion relation takes the Radix Panacis Quinquefolii of each weight portion, Herba Belladonnae, Rhizoma Acori Calami, Mentholum, Poria, Herba Corydalis, Radix Salviae Miltiorrhizae, Cortex Mori；Add
70% ethanol soaks 15 minutes at 60～65 DEG C, reflux, extract, 2-3 time, each 1 hour, and 100 mesh filters filter, and obtain extracting solution；
United extraction liquid, recovered under reduced pressure in input concentrating under reduced pressure tank, ethanol, to without alcohol taste, obtains concentrated solution；By concentrated solution at 70-100 DEG C
Being spray-dried or dry, be ground into the fine powder of 70-100 mesh, after granulation, Conventional compression or encapsulated, to obtain final product.
Prescription of the present invention is exquisite, each component synergism, analgesia of releiving, warming the stomach spleen invigorating, and desilting helps digestion, and burns the heart for gastric heat
Person is especially suitable.
Detailed description of the invention
Embodiment 1
(1) Radix Panacis Quinquefolii 1 part, Herba Belladonnae 3 parts, Rhizoma Acori Calami 6 parts, Mentholum 0.1 part, 6 parts of Poria, Herba Corydalis 8 parts, Radix Salviae Miltiorrhizae are taken
1 part, Cortex Mori 1 part standby；
(2) adding 70% ethanol to soak 15 minutes at 60 DEG C, reflux, extract, 2 times, each 1 hour, 100 mesh filters filter,
Extracting solution；United extraction liquid, recovered under reduced pressure in input concentrating under reduced pressure tank, ethanol, to without alcohol taste, obtains concentrated solution；By concentrated solution 70
DEG C be spray-dried or dry, be ground into the fine powder of 70 mesh, encapsulated after granulation, specification 0.45g/ grain. each 3 times of morning, noon and afternoon, ante cibum
Take, each 3-5 grain.
Embodiment 2
(1) Radix Panacis Quinquefolii 3 parts, Herba Belladonnae 5 parts, Rhizoma Acori Calami 8 parts, Mentholum 0.3 part, 8 parts of Poria, Herba Corydalis 12 parts, pellet are taken
Join 3 parts, Cortex Mori 3 parts standby；
(2) adding 70% ethanol to soak 15 minutes at 65 DEG C, reflux, extract, 3 times, each 1 hour, 100 mesh filters filter,
Extracting solution；United extraction liquid, recovered under reduced pressure in input concentrating under reduced pressure tank, ethanol, to without alcohol taste, obtains concentrated solution；Concentrated solution is existed
100 DEG C are spray-dried or dry, are ground into the fine powder of 100 mesh, encapsulated after granulation, specification 0.45g/ grain.
Embodiment 3
(1) Radix Panacis Quinquefolii 2 parts, Herba Belladonnae 4 parts, Rhizoma Acori Calami 7 parts, Mentholum 0.2 part, 7 parts of Poria, Herba Corydalis 10 parts, pellet are taken
Join 2 parts, Cortex Mori 2 parts standby；
(2) adding 70% ethanol to soak 15 minutes at 62 DEG C, reflux, extract, 2 times, each 1 hour, 100 mesh filters filter,
Extracting solution；United extraction liquid, recovered under reduced pressure in input concentrating under reduced pressure tank, ethanol, to without alcohol taste, obtains concentrated solution；By concentrated solution 80
DEG C be spray-dried or dry, be ground into the fine powder of 90 mesh, encapsulated after granulation, specification 0.45g/ grain.
Clinical efficacy data
1, the effect observation that has a stomach-ache is treated
1.1 objects: flatulence pain observation 500 people, with gastralgia, hyperchlorhydria and the chronic dietary stagnation of QI, stool the hardest after
Half congealed, belch, stomach has burn feeling.
1.2 medicine compositions: Radix Panacis Quinquefolii 200 grams, Herba Belladonnae 400 grams, Rhizoma Acori Calami 700 grams, Mentholum 20 grams, Poria
700 grams, Herba Corydalis 1000 grams, Radix Salviae Miltiorrhizae 200 grams, Cortex Mori 200 grams.
Said medicine adds 70% ethanol soak 15 minutes at 62 DEG C, reflux, extract, 2 times, each 1 hour, 100 mesh filters
Filter, obtain extracting solution；United extraction liquid, recovered under reduced pressure in input concentrating under reduced pressure tank, ethanol, to without alcohol taste, obtains concentrated solution；By dense
Contracting liquid is spray-dried at 80 DEG C or dries, and is ground into the fine powder of 90 mesh, and encapsulated after granulation, specification 0.45g/ grain, the morning, noon and afternoon are each
Once, bfore meals, each 3-5 grain.
1.3 curative effect judging standards:
Cure: gastralgia and other transference cures, x line, canel barium meal contrast examination or gastroscopy are normal.
Taking a turn for the better: stomachache is alleviated, outbreak reduces, other symptoms alleviate.
Not healing: x line, canel barium meal contrast examination or gastroscopy are the same with premorbid, symptom is without improving and taking a turn for the better.
Treatment stomachache 500 example effects
After using 30 days, 500 examples effective 377 examples of stomachache, take a turn for the better 85 examples, invalid 38 examples, obvious effective rate 75%, improvement rate
17%, total effective rate 92%.In use, all user all reflect that appetite improves, appetite increase, and stool form and
Color makes moderate progress.
Claims (3)
1. the Chinese medicine composition treating flatulence pain, it is characterised in that include the raw material of following weight portion: Radix Panacis Quinquefolii 1-3, top
Eggplant grass 3-5, Rhizoma Acori Calami 6-8, Mentholum 0.1-0.3, Poria 6-8, Herba Corydalis 8-12, Radix Salviae Miltiorrhizae 1-3, Cortex Mori 1-3.
A kind of Chinese medicine composition treating flatulence pain the most according to claim 1, it is characterised in that include following weight portion
Raw material: Radix Panacis Quinquefolii 2, Herba Belladonnae 4, Rhizoma Acori Calami 7, Mentholum 0.2, Poria 7, Herba Corydalis 10, Radix Salviae Miltiorrhizae 2, Cortex Mori 2.
The preparation method of a kind of Chinese medicine composition treating flatulence pain the most according to claim 1 and 2: it is characterized in that bag
Containing following process steps: take the Radix Panacis Quinquefolii of each weight portion by proportion relation, Herba Belladonnae, Rhizoma Acori Calami, Mentholum, Poria, Herba Corydalis,
Radix Salviae Miltiorrhizae, Cortex Mori；Add 70% ethanol to soak 15 minutes at 60～65 DEG C, reflux, extract, 2-3 time, each 1 hour, 100 mesh filters
Filter, obtain extracting solution；United extraction liquid, recovered under reduced pressure in input concentrating under reduced pressure tank, ethanol, to without alcohol taste, obtains concentrated solution；By dense
Contracting liquid is spray-dried at 70-100 DEG C or dries, and is ground into the fine powder of 70-100 mesh, Conventional compression or encapsulated after granulation, i.e.
?.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107802804A (en) * | 2017-11-13 | 2018-03-16 | 江苏华晶生物科技有限公司 | A kind of Chinese medicine composition containing milk thistle treatment gasteremphraxis pain |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104740322A (en) * | 2015-04-01 | 2015-07-01 | 四川宇妥藏药股份有限公司 | Chinese medicinal tablets and preparation method thereof |
| CN105343797A (en) * | 2015-12-11 | 2016-02-24 | 李建敏 | Traditional Chinese medicine composition for curing stomach illness and preparation method thereof |
| CN105362778A (en) * | 2015-12-14 | 2016-03-02 | 李建敏 | Traditional Chinese medicine composition for treating reflux gastritis and preparation method of traditional Chinese medicine composition |
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2016
- 2016-08-10 CN CN201610651426.2A patent/CN106138533A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104740322A (en) * | 2015-04-01 | 2015-07-01 | 四川宇妥藏药股份有限公司 | Chinese medicinal tablets and preparation method thereof |
| CN105343797A (en) * | 2015-12-11 | 2016-02-24 | 李建敏 | Traditional Chinese medicine composition for curing stomach illness and preparation method thereof |
| CN105362778A (en) * | 2015-12-14 | 2016-03-02 | 李建敏 | Traditional Chinese medicine composition for treating reflux gastritis and preparation method of traditional Chinese medicine composition |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107802804A (en) * | 2017-11-13 | 2018-03-16 | 江苏华晶生物科技有限公司 | A kind of Chinese medicine composition containing milk thistle treatment gasteremphraxis pain |
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Application publication date: 20161123 |