CN102058767B - Chinese medicine for treating senile chronic bronchitis and method for preparing pills thereof - Google Patents

Chinese medicine for treating senile chronic bronchitis and method for preparing pills thereof Download PDF

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CN102058767B
CN102058767B CN201110031338XA CN201110031338A CN102058767B CN 102058767 B CN102058767 B CN 102058767B CN 201110031338X A CN201110031338X A CN 201110031338XA CN 201110031338 A CN201110031338 A CN 201110031338A CN 102058767 B CN102058767 B CN 102058767B
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chinese medicine
chronic bronchitis
rhizoma
radix
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CN102058767A (en
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刘希孟
张玉萍
马芳
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Abstract

The invention discloses a Chinese medicine for treating senile chronic bronchitis and a method for preparing pills thereof. The Chinese medicine is prepared by taking houttuynia cordata, isatis root, cyrtomium fortunei, paris polyphylla, saposhnikovia divaricata, loquat leaf, astragalus mongholicus, atractylodes macrocephala koidz, angelica sinensis, schisandra chinensis, poria cocos, pinellia tuberifera, bitter almond, fritillaria cirrhosa, balloonflower root, flos farfarae, red tangerine peel, semen lepidii and glycyrrhiza as raw materials. The invention further provides the method for preparing pills of the Chinese medicine, which comprises the following steps of: grinding the nineteen medicines into powder with 60-80mesh after removing impurities and dust and processing, and preparingpills by a pill machine with cortex mori decocted liquid as a binding agent. A decoction and the pills of the Chinese medicine for treating senile chronic bronchitis can be matched to treat the chronic bronchitis with quick effect and prevent the chronic bronchitis from attacking once more. The Chinese medicine disclosed by the invention has excellent curative effect on the senile chronic bronchitis and small toxic and side effects, with 91% total effective rate.

Description

The Chinese medicine of treatment senile chronic bronchitis and the method for preparing of this medicine pill
Technical field
The present invention relates to field of Chinese herbal, particularly relate to a kind of Chinese medicine of treating senile chronic bronchitis and preparation method thereof.
Background technology
Chronic bronchitis is because infection or non-infective agent cause the chronic nonspecific inflammation of trachea, bronchial mucosa and surrounding tissue thereof.Its pathological characteristic is that bronchus body of gland hypertrophy, mucous secretion increase.Be the commonly encountered diseases and the frequently-occurring disease of serious harm people ' s health, see with the old people more especially that the person is up to about 15% more than 50 years old.Early symptom is slight, and how in the winter time outbreak is alleviated after the spring is warm; Late period, inflammation increased the weight of, and symptom exists all the year round, was regardless of season.The senile chronic bronchitis patient age is big, and the course of disease is long, and passive protective physical fitness is low.Especially severe winter is careless slightly, and pathogen just gets into health easily, causes the inflammation of respiratory tract.Chronic bronchitis further develops can concurrent obstructive emphysema, pulmonary heart disease, heavy then heart failure takes place, even threat to life.Primary disease belongs to Chinese medicine " cough ", " phlegm retention ", " cough with asthma " category.The traditional Chinese medical science is thought the invasion and attack repeatedly of the generation of primary disease and exopathogen normal with development, and lung, spleen, kidney three dirty functional disorders are closely related.Acute attack stage, mostly because of insufficiency of lung-QI, the invasion of weakened defensive QI exopathogen, so that cough outbreak repeatedly; Or because of chronic cough endlessly, outbreak repeatedly, or body is empty with age, lung spleen deficiency of kidney-QI, water Tianjin is cloth not, stops in the phlegm retention, checks in lung, causes long-term cough with asthma, or injure in lung, and then form primary disease because of smoking, factor such as drink.Pathological changes is prolonged not to heal, and then the lung spleen undermines in kidney, so that the person of being in a bad way often can not put down with asthma is for sleeping in, moving then more so wait the time of failure of the kidney in receiving QI.To its treatment, doctor trained in Western medicine stresses that antibiotic, relieving cough and resolving phlegm agent, spasmolytic anti-asthmatic are the most frequently used Western medicine of treatment chronic bronchitis.Though rapid-action, erious adverse reaction, curative effect is difficult to lastingly.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine of treating senile chronic bronchitis.
Another object of the present invention provides a kind of method for preparing of treating the senile chronic bronchitis medicine pill.
The present invention treats that medical material in the raw material of Chinese medicine of senile chronic bronchitis is formed and the weight portion proportioning is:
35-45 parts of Herba Houttuyniae, 21-27 parts of Radix Isatidis, 18-24 parts of Rhizoma Osmundae, 21-25 parts of Rhizoma Paridis,
Windproof 24-30 parts, 21-28 parts of Folium Eriobotryaes, 36-45 parts of the Radixs Astragali, 24-35 parts of the Rhizoma Atractylodis Macrocephalaes,
15-21 parts of Radix Angelicae Sinensis, 15-21 parts of Fructus Schisandrae Chinensis, 24-33 parts in Poria, 9-15 parts of Rhizoma Pinelliae,
12-18 parts of Semen Armeniacae Amarums, 30-42 parts of Bulbus Fritillariae Cirrhosaes, 15-24 parts of Radix Platycodoniss, 24-30 parts of Flos Farfaraes,
18-28 parts of tangerine 18-24 parts, lepidii,semen and 15-21 parts in Radix Glycyrrhizae.
Medical material in the raw material of Chinese medicine of the present invention is formed and the weight portion proportion optimization is:
39 parts of Herba Houttuyniae, 24 parts of Radix Isatidis, 21 parts of Rhizoma Osmundae, 22 parts of Rhizoma Paridis,
Windproof 27 parts, 25 parts of Folium Eriobotryaes, 42 parts of the Radixs Astragali, 30 parts of the Rhizoma Atractylodis Macrocephalaes,
18 parts of Radix Angelicae Sinensis, 18 parts of Fructus Schisandrae Chinensis, 27 parts in Poria, 12 parts of Rhizoma Pinelliae,
16 parts of Semen Armeniacae Amarums, 36 parts of Bulbus Fritillariae Cirrhosaes, 21 parts of Radix Platycodoniss, 28 parts of Flos Farfaraes,
18 parts in tangerine 21 parts, 24 parts of lepidii,semens and Radix Glycyrrhizae.
Solution of the present invention is based on motherland's medical science to senile chronic bronchitis and pathogenetic understanding and Therapeutic Principle; Achieve with reference to modern pharmacological research; Carry out the brand-new prescription of Chinese herbal medicine by theory of Chinese medical science, realize effective treatment senile chronic bronchitis.
Chinese medicine of the present invention can be any dosage form on the pharmaceutics.
Method for preparing of the present invention:
1, medicine of the present invention also can be processed pill according to following method:
A, 19 herbal medicines in the claim 1 are removed impurity, dust, concoct (Semen Armeniacae Amarum peeling, microwave bake 5 minutes, other crude drug that need concoct are all concocted according to pharmacological method) after, be ground into 60-80 purpose Chinese traditional powder, fully mix thoroughly, sealing is preserved subsequent use;
B, weighting profit require the Cortex Mori of 1/2 times of 19 herbal medicine gross weight in 1, and the clear water that adds 10 times of Cortex Mori weight again decocted 50-60 minute, mix, filter, concentrate decoction liquor and get Cortex Mori filtrating;
C, Cortex Mori filtrating among Chinese traditional powder in the steps A and the step B is mixed to join in the pellet processing machine stir, pill, and under 80 ℃ constant temperature pill drying;
D, with pill pack sugar-coat, polishing among the step C, low temperature (35 ℃-40 ℃) drying, packing promptly gets.2, decoction: above 19 herbal medicines are added 500 milliliters of slow fire of water by above-mentioned weight fry in shallow oil half an hour slowly, get supernatant.Subsequent use.
The method for using of Chinese medicine of the present invention:
During each acute attack, potion clear water decoction every day, sooner or later respectively once.It is oral with crystal sugar 20 grams (except the glycosuria patient) to get supernatant when taking, and serve on 5 days.The 6th day beginning, take pill, each 6-9 grams, got final product at every day 3 times in 7-10 days.
In the Chinese prescription of the present invention, the Herba Houttuyniae acrid in the mouth is slightly cold, heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus; The Radix Isatidis bitter in the mouth, cold.Heat-clearing and toxic substances removing; The Rhizoma Osmundae bitter in the mouth is slightly cold, heat-clearing and toxic substances removing, removing heat from blood virus killing; The Rhizoma Paridis bitter in the mouth is slightly cold; Heat-clearing and toxic substances removing, antiasthmatic-antitussive; Windproof acrid in the mouth, sweet, temperature is analgesicly dispeled the wind, is delivered; The Folium Eriobotryae bitter in the mouth, be slightly cold clearing away lung-heat to relieve cough, sputum eliminating to stop asthma; Be monarch drug.Radix Astragali sweet in the mouth, tepor, benefit are defended consolidating superficial resistance, tonifying Qi and lifting yang, inducing diuresis to remove edema; Rhizoma Atractylodis Macrocephalae bitter in the mouth, sweet, warm in nature, air making-up and spleen enlivening, dampness diuretic, hidroschesis; Radix Angelicae Sinensis is warm in nature, sweet in the mouth, suffering, but circulation of qi promoting enrich blood, invigorate blood circulation; Fructus Schisandrae Chinensis sweet in the mouth, acid, warm in nature, astringing lung-QI and relieving cough, supplementing QI for promoting the production of body fluid, kidney calming is ministerial drug; Poria sweet in the mouth, light, property is flat, promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming; Rhizoma Pinelliae acrid in the mouth, warm in nature, drying dampness to eliminate phlegm, falling greasy preventing or arresting vomiting is adjuvant drug.Semen Armeniacae Amarum is warm in nature, bitter in the mouth; Relieving cough and asthma, loosening bowel to relieve constipation; Bulbus Fritillariae Cirrhosae bitter in the mouth, sweet, cold nature.But removing heat-phlegm, nourishing the lung to arrest cough; Radix Platycodonis bitter in the mouth, suffering, property is flat, lung qi dispersing sore-throat relieving, the evacuation of pus of eliminating the phlegm; The Flos Farfarae acrid in the mouth, temperature, nourishing the lung to keep the adverse QI downward, relieving cough and resolving phlegm; Tangerine acrid in the mouth, hardship, warm in nature, cold expelling dampness, activating QI to eliminate phlegm; Lepidii,semen acrid in the mouth, hardship, cold in nature, eliminating pathogen from the lung for relieving asthma, inducing diuresis to remove edema are messenger drug.The Radix Glycyrrhizae sweet in the mouth, property is flat, invigorating the spleen and replenishing QI, nourishing the lung to arrest cough, heat-clearing and toxic substances removing, the mediation property of medicine.Above-mentioned 19 flavor Chinese herbal medicine are assisted a ruler in governing a country through dialectical prescription, organic compatibility each other, can reach heat-clearing and toxic substances removing, benefit is defended consolidating superficial resistance, tonifying Qi and lifting yang, removing heat-phlegm, the effect of nourishing the lung to arrest cough, thus realize the purpose of treatment senile chronic bronchitis.
The effect that Chinese medicine decoction of the present invention cooperates pill treatment chronic bronchitis both to have immediate effect, the effect that has the chronic bronchitis of preventing to show effect once more again.Senile chronic bronchitis is had excellent curative, and toxic and side effects is little.
The acute toxicity test of Chinese medicine of the present invention is following:
One, experiment material
Animal: Kunming kind white mice is provided by laboratory animal room of Lanzhou Institute of Biological Products, and body weight is (20 ± 2) g.
Medicine: this Chinese prescription with distilled water slow fire fry in shallow oil slowly concentrate after half an hour subsequent use.
Method: mtd test
60 of female mices, experiment the previous day, water is can't help in fasting overnight, under the condition of 20 ± 2 ℃ of room temperatures, gastric infusion twice in 24 hours, dosage is 15.0g/Kg, observes for two weeks after the administration.
Mice in 30 minutes, because the administration volume is bigger than normal, has discomfort slightly after administration as a result, and it shows as mice and has loose bowels; Back of a bow phenomenon recovers normal subsequently rapidly, and quiet, observes for two weeks continuously; Mice all survives, and cuts open inspection, and naked eyes examine main inner internal organs, no abnormality seen.
Conclusion: according to the requirement of Chinese medicine toxicological study, can accept the maximum volume under the Cmax, carry out mtd test mice.Mice is all survivals in the observation period, do not see overt toxicity, show that this poison of drug property is very little, and is clinical safe in utilization.
Clinical research data of the present invention is following:
1. physical data
Selected 685 routine cases are and are diagnosed as the patient of chronic bronchitis at my gate year June in January, 2005 to 2010, the age between 60 years old-82 years old, average 71 years old.Wherein male 289 examples, women 395 examples.The course of disease 3 years-25 years, average 15 years.Smoking history 225 examples, history of drinking history 170 examples.Merge chronic obstructive pulmonary disease 156 examples, hypertension 67 examples, coronary heart disease 35 examples, diabetes 21 examples, gout 3 examples, pulmonary tuberculosis 13 examples.Once treated with Chinese and western drugs mostly, poor effect, symptom does not improve.
2. diagnostic criteria
(1) cough, expectoration or companion pant, annual morbidity 3 months, continuous 2 years or above person.
(2) annual morbidity less than is 3 months, and has clear and definite objective determination also diagnosable according to (like X line, determination of respiratory function etc.) person.
(3) can get rid of other hearts, lung disease (like pulmonary tuberculosis, asthma, bronchiectasis, pulmonary carcinoma, heart disease etc.) person.
Be characteristic with long-term intractable cough clinically.When sooner or later lower the or diet of temperature stimulates, send out again and again and cough.During no complication, body temperature, pulse no change.The sick no change of just breathing, later on owing to bronchial mucosa connective tissue proliferation thickening, the bronchus tube chamber changes narrow, and dyspnea then takes place.When concurrent emphysema, breathing is the devil, and this dyspneic characteristic is respiratory or blended, and the intercostal pouch is arranged and breath labor ditch occurs.Chest auscultation, vesicluar sound strengthen, and vesicluar sound weakens during concurrent emphysema, often can hear dry rale.Chest percussion pitch is bright, and lung circle is loose.The X ray examination, the bronchus shade of pulmonary increases weight and prolongs.
3. observation index
The one, observe cough, expectoration is panted and is waited clinical manifestation to improve situation, and the 2nd, observe pulmonary's wheezing sound and improve situation, the 3rd, the observation of laboratory blood gas analysis.
4. Therapeutic Method
More than 685 routine patients be divided into two groups at random, 345 examples are organized in treatment, male 145 examples, women 200 examples, 60-81 years old ages, average 70.5 years old; Observation group's 340 examples, male 138 examples, women 202 examples, 61-82 years old ages, average 71.5 years old.Two groups of patients all give penicillin or cefazolin injection intravenous drip antiinflammatory. and the treatment group adds uses above-mentioned treatment by Chinese herbs, in acute attack stage, potion clear water decoction every day, sooner or later respectively once.It is oral with crystal sugar 20 grams to get supernatant when taking, and serve on 5 days; The 6th day beginning, take pill, each 6 grams, got final product at every day 3 times in 7-10 days.
5. clinical efficacy is judged
5.1 the acute attack stage curative effect is judged:
Clinic control (facing control): symptom and pulmonary wheezing sound are not enough slight person, or cough, expectorant, asthma shape takes a turn for the better more than ninety percent.Or pulmonary's wheezing sound returns to the preceding level of acute attack.PaO2>95mmHg, PaCO2 < 34mmHg, SaO2>95%, PH is normal.
Produce effects: cough, expectorant, asthma shape takes a turn for the better more than sixty percent, or symptom and pulmonary's wheezing sound be clearly better, but do not return to level before the acute attack.PaO2 90-95mmHg, PaCO2 < 40mmHg, SaO2>90%, PH is normal.
Take a turn for the better: cough, expectorant, asthma shape takes a turn for the better more than three one-tenth, or symptom and pulmonary's wheezing sound take a favorable turn.PaO2>85mmHg, PaCO2 < 45mmHg, SaO2>85%, PH is normal or on the low side.
Invalid: symptom and pulmonary's heavy breathing toot sound do not have change, or three one-tenth persons of improvement less than, and symptom and the wheezing sound person of increasing the weight of of pulmonary.PaO2 < 60mmHg, PaCO2>45mmHg, < 85%, PH reduces SaO2.
The blood gas analysis synopsis
Curative effect is judged paO2(mmhg) PaCO2(mmhg) SaO2(%) PH
Face control >95 <34 >95 Normally
Produce effects 90-95 <40 90-95 Normally
Take a turn for the better >85 <45 >85 Normal or on the low side
Invalid <85 >45 <85 Reduce
5.2 therapeutic outcome:
In order to last scheme 2 cycles of treatment, 345 examples, the 340 routine senile chronic bronchitis patients of observation group are organized in treatment, two groups of effective percentage of result are respectively treatment group 91% and observation group 76%, two group of treatment back result, and there were significant differences (P 0.05).The treatment situation sees the following form:
Divide into groups The example number Face control Produce effects Effectively Invalid Effective percentage
The treatment group 345 71 116 126 32 91%
Matched group 340 63 91 104 82 76%
Clinical research is the result show: evident in efficacy with this Chinese prescription treatment senile chronic bronchitis, chronic obstructive emphysema, and toxic and side effects is little.
The specific embodiment
Following embodiment can further specify the present invention, but does not limit the present invention in any way.
Embodiment 1
Medical material in the raw material consists of:
Herba Houttuyniae 39 grams, Radix Isatidis 24 grams, Rhizoma Osmundae 21 restrain, Rhizoma Paridis 22 grams, windproof 27 restrain,
Folium Eriobotryae 25 grams, the Radix Astragali 42 grams, the Rhizoma Atractylodis Macrocephalae 30 grams, Radix Angelicae Sinensis 18 restrain, Fructus Schisandrae Chinensis 18 restrains,
Poria 27 grams, Rhizoma Pinelliae 12 grams, Semen Armeniacae Amarum 16 grams, Bulbus Fritillariae Cirrhosae 36 restrain, Radix Platycodonis 21 restrains,
Flos Farfarae 28 grams, tangerine 28 grams, lepidii,semen 24 grams and Radix Glycyrrhizae 18 grams.
1, decoction method for making: above crude drug is added 500 milliliters of slow fire of water by above-mentioned weight fry in shallow oil half an hour slowly, get supernatant.Subsequent use.
2, pill method for making:
A, above-mentioned 19 herbal medicines are removed impurity, dust, concoct (Semen Armeniacae Amarum peeling, microwave bake 5 minutes, other all concoct according to pharmacological method with the crude drug of concocting) after, be ground into 60-80 purpose Chinese traditional powder, fully mix thoroughly, the sealing preservation is subsequent use;
B, weighting profit require the Cortex Mori of 1/2 times of crude drug gross weight in 1, and the clear water that adds 10 times of Cortex Mori weight again decocted 50-60 minute, mix, filter, concentrate decoction liquor and get Cortex Mori filtrating;
C, Cortex Mori filtrating among Chinese traditional powder in the steps A and the step B is mixed to join in the pellet processing machine stir, pill, and under 80 ℃ constant temperature pill drying;
D, with pill pack sugar-coat, polishing among the step C, low temperature (35 ℃-40 ℃) drying, packing promptly gets.2, decoction: above 19 herbal medicines are added 500 milliliters of slow fire of water by above-mentioned weight fry in shallow oil half an hour slowly, get supernatant.Subsequent use.
Instructions of taking:
During each acute attack, potion clear water decoction every day, sooner or later respectively once.It is oral with crystal sugar 20 grams (except the glycosuria patient) to get supernatant when taking, and serve on 5 days.The 6th day beginning, take pill, each 6 grams, got final product at every day 3 times in 7-10 days.
Embodiment 2 the present invention to the body constitution element a little less than, the insufficiency of QI of the lung and kidney senile chronic bronchitis provides the medical material in the composition material of enforcement to consist of:
Herba Houttuyniae 35 grams, Radix Isatidis 21 grams, Rhizoma Osmundae 18 restrain, Rhizoma Paridis 21 grams, windproof 24 restrain,
Folium Eriobotryae 21 grams, the Radix Astragali 36 grams, the Rhizoma Atractylodis Macrocephalae 24 grams, Radix Angelicae Sinensis 15 restrain, Fructus Schisandrae Chinensis 15 restrains,
Poria 24 grams, Rhizoma Pinelliae 9 grams, Semen Armeniacae Amarum 12 grams, Bulbus Fritillariae Cirrhosae 30 restrain, Radix Platycodonis 15 restrains,
Flos Farfarae 24 grams, tangerine 25 grams, lepidii,semen 18 grams and Radix Glycyrrhizae 15 grams.
Method for making and instructions of taking are with embodiment 1.
Embodiment 3 the present invention are plain strong to body constitution, the medical material in the hot composition material that accumulates the lung senile chronic bronchitis and provide enforcement of expectorant consists of:
Herba Houttuyniae 45 grams, Radix Isatidis 27 grams, Rhizoma Osmundae 24 restrain, Rhizoma Paridis 25 grams, windproof 30 restrain,
Folium Eriobotryae 28 grams, the Radix Astragali 45 grams, the Rhizoma Atractylodis Macrocephalae 35 grams, Radix Angelicae Sinensis 21 restrain, Fructus Schisandrae Chinensis 21 restrains,
Poria 33 grams, Rhizoma Pinelliae 15 grams, Semen Armeniacae Amarum 16 grams, Bulbus Fritillariae Cirrhosae 42 restrain, Radix Platycodonis 24 restrains,
Flos Farfarae 30 grams, tangerine 30 grams, lepidii,semen 28 grams and Radix Glycyrrhizae 21 grams.
Method for making and instructions of taking are with embodiment 1.

Claims (1)

1. Chinese medicine of treating senile chronic bronchitis is characterized in that medical material in the raw material is formed and the weight portion proportioning is:
35-45 parts of Herba Houttuyniae, 21-27 parts of Radix Isatidis, 18-24 parts of Rhizoma Osmundae, 21-25 parts of Rhizoma Paridis,
Windproof 24-30 parts, 21-28 parts of Folium Eriobotryaes, 36-45 parts of the Radixs Astragali, 24-35 parts of the Rhizoma Atractylodis Macrocephalaes,
15-21 parts of Radix Angelicae Sinensis, 15-21 parts of Fructus Schisandrae Chinensis, 24-33 parts in Poria, 9-15 parts of Rhizoma Pinelliae,
12-18 parts of Semen Armeniacae Amarums, 30-42 parts of Bulbus Fritillariae Cirrhosaes, 15-24 parts of Radix Platycodoniss, 24-30 parts of Flos Farfaraees,
18-28 parts of tangerine 18-24 parts, lepidii,semen and 15-21 parts in Radix Glycyrrhizae.
2. the Chinese medicine of treatment senile chronic bronchitis according to claim 1 is characterized in that medical material composition and the weight portion proportioning in the raw material is:
39 parts of Herba Houttuyniae, 24 parts of Radix Isatidis, 21 parts of Rhizoma Osmundae, 22 parts of Rhizoma Paridis,
Windproof 27 parts, 25 parts of Folium Eriobotryaes, 42 parts of the Radixs Astragali, 30 parts of the Rhizoma Atractylodis Macrocephalaes,
18 parts of Radix Angelicae Sinensis, 18 parts of Fructus Schisandrae Chinensis, 27 parts in Poria, 12 parts of Rhizoma Pinelliae,
16 parts of Semen Armeniacae Amarums, 36 parts of Bulbus Fritillariae Cirrhosaes, 21 parts of Radix Platycodoniss, 28 parts of Flos Farfaraees,
18 parts in tangerine 21 parts, 24 parts of lepidii,semens and Radix Glycyrrhizae.
3. the Chinese medicine of treatment senile chronic bronchitis according to claim 1 and 2 is characterized in that: this Chinese medicine is any dosage form on the pharmaceutics.
4. pill method for preparing of treating the Chinese medicine of senile chronic bronchitis is characterized in that being made up of the following step:
A, get 35-45 parts of Herba Houttuyniae, 21-27 parts of Radix Isatidis, 18-24 parts of Rhizoma Osmundae, 21-25 parts of Rhizoma Paridis, windproof 24-30 parts, 21-28 parts of Folium Eriobotryaes, 36-45 parts of the Radixs Astragali, 24-35 parts of the Rhizoma Atractylodis Macrocephalaes,
15-21 parts of Radix Angelicae Sinensis, 15-21 parts of Fructus Schisandrae Chinensis, 24-33 parts in Poria, 9-15 parts of Rhizoma Pinelliae,
12-18 parts of Semen Armeniacae Amarums, 30-42 parts of Bulbus Fritillariae Cirrhosaes, 15-24 parts of Radix Platycodoniss, 24-30 parts of Flos Farfaraees,
18-28 parts of tangerine 18-24 parts, lepidii,semen and 15-21 parts in Radix Glycyrrhizae are removed impurity, dust with this 19 herbal medicine, after the process of preparing Chinese medicine, are ground into 60-80 purpose Chinese traditional powder, fully mix thoroughly, and sealing is preserved subsequent use;
B, get the Cortex Mori of 1/2 times of 19 herbal medicine gross weight in the steps A, the clear water that adds 10 times of Cortex Mori weight again decocted 50-60 minute, mixed, filters, concentrated decoction liquor and get Cortex Mori filtrating;
C, Cortex Mori filtrating among Chinese traditional powder in the steps A and the step B is mixed to join in the pellet processing machine stir, pill, and under 80 ℃ constant temperature pill drying;
D, with pill pack sugar-coat, polishing among the step C, dry under 35 ℃ of-40 ℃ of temperature, packing promptly gets.
5. pill method for preparing of treating the Chinese medicine of senile chronic bronchitis is characterized in that being made up of the following step:
18 parts in A, 39 parts of Herba Houttuyniae, 24 parts of Radix Isatidis, 21 parts of Rhizoma Osmundae, 22 parts of Rhizoma Paridis, windproof 27 parts, 25 parts of Folium Eriobotryaes, 42 parts of the Radixs Astragali, 30 parts of the Rhizoma Atractylodis Macrocephalaes, 18 parts of Radix Angelicae Sinensis, 18 parts of Fructus Schisandrae Chinensis, 27 parts in Poria, 12 parts of Rhizoma Pinelliae, 16 parts of Semen Armeniacae Amarums, 36 parts of Bulbus Fritillariae Cirrhosaes, 21 parts of Radix Platycodoniss, 28 parts of Flos Farfaraees, tangerine 21 parts, 24 parts of lepidii,semens and Radix Glycyrrhizae; This 19 herbal medicine is removed impurity, dust; After the process of preparing Chinese medicine; Be ground into 60-80 purpose Chinese traditional powder, fully mix thoroughly, sealing is preserved subsequent use;
B, get the Cortex Mori of 1/2 times of 19 herbal medicine gross weight in the steps A, the clear water that adds 10 times of Cortex Mori weight again decocted 50-60 minute, mixed, filters, concentrated decoction liquor and get Cortex Mori filtrating;
C, Cortex Mori filtrating among Chinese traditional powder in the steps A and the step B is mixed to join in the pellet processing machine stir, pill, and under 80 ℃ constant temperature pill drying;
D, with pill pack sugar-coat, polishing among the step C, dry under 35 ℃ of-40 ℃ of temperature, packing promptly gets.
CN201110031338XA 2011-01-28 2011-01-28 Chinese medicine for treating senile chronic bronchitis and method for preparing pills thereof Expired - Fee Related CN102058767B (en)

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CN104815208A (en) * 2015-04-30 2015-08-05 刘伟 Traditional Chinese medicine preparation for treating chronic obstructive pulmonary diseases and production method of traditional Chinese medicine preparation
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CN105168931A (en) * 2015-09-29 2015-12-23 济南伟传信息技术有限公司 Traditional Chinese medicine composite for treating chronic trachitis
CN113171430A (en) * 2021-04-14 2021-07-27 大方县九龙天麻开发有限公司 Gastrodia elata and polygonatum sibiricum granules and preparation method thereof
CN115025174B (en) * 2022-06-28 2023-06-02 杨永华 A Chinese medicinal composition for treating chronic obstructive pulmonary disease, and its preparation method

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