CN104815208A - Traditional Chinese medicine preparation for treating chronic obstructive pulmonary diseases and production method of traditional Chinese medicine preparation - Google Patents

Traditional Chinese medicine preparation for treating chronic obstructive pulmonary diseases and production method of traditional Chinese medicine preparation Download PDF

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CN104815208A
CN104815208A CN201510213339.4A CN201510213339A CN104815208A CN 104815208 A CN104815208 A CN 104815208A CN 201510213339 A CN201510213339 A CN 201510213339A CN 104815208 A CN104815208 A CN 104815208A
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radix
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刘伟
范晓娟
李宗霞
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Abstract

The invention discloses a traditional Chinese medicine preparation for treating chronic obstructive pulmonary diseases. The traditional Chinese medicine preparation is prepared from Chinese thorowax root, chrysanthemum, dwarf lilyturf tuber, figwort root, rehmannia root, ephedra herb, cassia twig, white peony root, reddish orange, platycodon root, fineleaf schizonepeta herb, divaricate saposhnikovia root, honeysuckle flower, baikal skullcap root, heartleaf houttuynia herb, danshen, Chinese honeylocust spine, safflower, fried peach seed, earthworm, prepared leech, medicinal cyathula root, milkvetch root, manyflower solomonseal rhizome, reed rhizome, Chinese angelica and honey-fried liquorice root in a certain weight ratio. The traditional Chinese medicine preparation has the effects of moistening lung and nourishing yin, removing heat to cool blood, freeing lung and relieving asthma, and relieving sore-throat and expelling pus, and is capable of effectively treating the chronic obstructive pulmonary diseases.

Description

A kind of Chinese medicine preparation for the treatment of chronic obstructive pulmonary disease and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine preparation, be specifically related to a kind of Chinese medicine preparation for the treatment of chronic obstructive pulmonary disease.The invention still further relates to the preparation method of this Chinese medicine preparation.
Background technology
Chronic obstructive pulmonary disease is a kind of important chronic respiratory system diseases, and number of patients is many, and case fatality rate is high.Due to its slow Progressive symmetric erythrokeratodermia development, have a strong impact on work capacity and the quality of life of patient.Patients with chronic obstructive pulmonary diseases is after acute attack stage, though clinical symptoms is alleviated to some extent, its pulmonary function still worsens in continuation, and due to self-defense and the reduction of immunologic function and the impact of extraneous various harmful factor, frequent recurrent exerbation, and produce various Cardiopulmonary Complications gradually.This disease is a kind of destructive pulmonary disease, is the disease that is feature with not exclusively reversible flow limitation, the flow limitation development react relevant with the abnormal inflammatory of lung to deleterious particle or gas in Progressive symmetric erythrokeratodermia usually.Although chronic obstructive pulmonary disease is the disease of air flue, the systematic influence of whole body also be can not be ignored.The cardinal symptom performance taste of this disease is l, chronic cough.Normal daystart cough obviously, has apasm of coughing or expectoration night.2, expectoration.Be generally white slimy or serosity frothy sputum, occasionally can be with the blood streak, early morning, expectoration was more.Acute attack stage amount of expectoration increases, and can have purulent sputum.3, to breathe hard or dyspnea.Occur when labour in early days, after increase the weight of gradually so that daily routines even rest time also feel to breathe hard.It is the significant symptom of chronic obstructive pulmonary disease.4, to pant and uncomfortable in chest.Some patients particularly severe patient or acute exacerbation time occur panting.5, other.Patients with terminal has weight loss, loss of appetite etc.
Mostly the medicine of current treatment chronic obstructive pulmonary disease is that index is not effected a permanent cure, although clinical symptoms is alleviated to some extent, but pulmonary function is still continuous worsening, and due to self-defense and the reduction of immunologic function and the impact of extraneous various harmful factor, frequent recurrent exerbation, great misery is brought to patient, the traditional Chinese medical science is often good at dialectical treating in treatment chronic disease, removes focus, based on nourishing YIN and moistening the lung, improving inspiration by invigorating the kidney from root, alleviate the slight illness of patient, thus reach the effect for the treatment of.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine preparation, this Chinese medicine preparation has evident in efficacy for treatment chronic obstructive pulmonary disease, cheap, easy to use, has no side effect, the feature of no dependence.
Another object of the present invention is to provide the preparation method of the Chinese medicine preparation of this treatment chronic obstructive pulmonary disease.
Inventor is in clinical treatment practice for many years, observe the misery that chronic obstructive pulmonary disease is brought to patient, according to the law of development of this disease, and the combination principle of Chinese medicine, and by a large amount of clinical verifications, Exploration and conclusion goes out a kind of new formula for the treatment of the Chinese medicine preparation of chronic obstructive pulmonary disease repeatedly, the present invention selects Radix Bupleuri, Flos Chrysanthemi, Radix Ophiopogonis, Radix Scrophulariae, Radix Rehmanniae, Herba Ephedrae, Ramulus Cinnamomi, the Radix Paeoniae Alba, Fructus Citri tangerinae is red, Radix Platycodonis, Herba Schizonepetae, Radix Saposhnikoviae, Flos Lonicerae, Radix Scutellariae, Herba Houttuyniae, Radix Salviae Miltiorrhizae, Spina Gleditsiae, Flos Carthami, Semen Persicae (parched), Pheretima, Hirudo (processed), Radix Cyathulae, the Radix Astragali, Rhizoma Polygonati, Rhizoma Phragmitis, Radix Angelicae Sinensis, Radix Glycyrrhizae Preparata combines, each efficacy of drugs is made by these drug regimens to produce synergism, make it that there is nourishing lung-YIN, clearing away heat and cooling blood, depressed lung-energy dispersing, effect of sore-throat relieving evacuation of pus, thus effectively can treat chronic obstructive pulmonary disease.
The effect of Chinese medicine of the present invention:
Wherein:
Radix Bupleuri: be Umbelliferae herbaceos perennial Radix Bupleuri Bupleurum chinense DC.(Radix Bupleuri) or Radix Bupeuri Scorzonerfolii. Bupleurum scorzonerifolium Willd.(Radix Bupleuri Scorzonerifolii) root or herb.Nature and flavor: bitter, pungent, be slightly cold.Return liver, gallbladder meridian.Effect: reducing fever by reconciliation, dispersing the stagnated live-QI to relieve the stagnation of QI, ascending up spleen-Qi and Yang.Modern pharmacological research proves: " medicineization justice ": Radix Bupleuri, and property is gently clear, and main liter falls apart, mildly bitter flavor, main soothing the liver." book on Chinese herbal medicine is through separating ": Radix Bupleuri, stagnation of QI person in its main trusted subordinate's the intestines and stomach, trusted subordinate's the intestines and stomach, five hide six mansions also, and Zang Fu is totally ten two warps, gallbladder is all depended in all 11 Tibetan, and Radix Bupleuri is gently clear, and rise and reach courage, courage bar reaches, then 11 hide from Xuanhua, therefore in trusted subordinate's the intestines and stomach, all have stagnation of QI, all can fall apart also.Its main diet accumulator, lid diet enters stomach, the spleen transporting essential substances to the liver, the evacuation of liver, borrow again few positive gallbladder be the master of hair growth promoting also, Radix Bupleuri liter reaches courage, then liver can fall apart essence, and diet gathers from lower.Shaoyang channel row half exterior and half interior, few sun, by evil, evilly also then to be trembled with fear in the moon, evil and in Yang Zere, Radix Bupleuri treating SHAO YANG disease by mediation, therefore the pathogen of main cold and heat also.
Flos Chrysanthemi: be the dry capitulum of feverfew chrysanthemum Chrysanthemum morifolium Ramat..Nature and flavor: sweet, bitter, are slightly cold.Return lung, Liver Channel.Effect: loose wind heat clearing away, suppressing the hyperactive liver improving eyesight.For anemopyretic cold, have a headache dizzy, conjunctival congestion and swelling pain, eyes is dim-sighted.Because this product can clearing away liver-fire, wind heat of faling apart again, can treat the various diseases caused by high liver fire.
Radix Ophiopogonis: be the dried root of liliaceous plant Radix Ophiopogonis (dwarf lilyturf) Ophiopogon japonicus (Thunb.) Ker-Gawl..Nature and flavor: sweet, micro-hardship, to be slightly cold.GUIXIN, lung, stomach warp.Effect: reinforcing stomach reg fluid, nourishing lung-YIN, clear away heart-fire relieving restlessness.Radix Ophiopogonis can clear away heart-fire in yin nourishing, and relieving restlessness is calmed the nerves.The heart-nutriment, fever aggravated at night is entered with controlling warm febrile disease.
Radix Scrophulariae: be the dry root of goatweed Radix Scrophulariae Scrophularia ningpoensis Hemsl..Nature and flavor: sweet, bitter, salty, are slightly cold.Return lung, stomach, kidney channel.Effect: clearing away heat and cooling blood, eliminating fire and detoxication, YIN nourishing.There is slight hypoglycemic activity.To join the army for: warm febrile disease the card of blood, consumption of YIN caused by febrile disease.There is clearing away heat and cooling blood, effect of removing toxic substances YIN nourishing.Control warm febrile disease to join the army blood, impairment of YIN robs the fever of the body excessive thirst caused by liquid.
Radix Rehmanniae: be the fresh or dried root of scrophulariaceae rehmannia glutinosa plant Rehmannia glutinosa Libosch..Nature and flavor: sweet, cold.GUIXIN, liver, kidney channel.Effect: clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting.Can be used for Tianjin wound thirsty, interior-heat is quenched one's thirst.This product is sweet cold, can among heat clearing away YIN nourishing and the production of body fluid promoting, cold in nature and enter blood system, can not only the heat of clearing heat in YING system blood system and removing heat from blood, and sweet in the mouth is cold in nature can promote the production of body fluid, and has the effect of nourishing YIN and clearing away heat.
Herba Ephedrae: be the dry herb stem of Ephedraceae plant plait Herba Ephedrae Ephedra sinica Stapf, epheday intermedia Ephedra intermedia Schrenk et C. A. Mey. or ephedra equisetina Ephedra equisetina Bge..Nature and flavor: pungent, micro-hardship, temperature.Return lung, urinary bladder channel.Effect: diaphoresis cold expelling, depressed lung-energy dispersing, inducing diuresis to remove edema.For anemofrigid cold, uncomfortable in chestly to breath with cough, edema due to wind pathogen edema; Bronchial asthma.Herba Ephedrae is warm in nature pungent loose, can diaphoresis cold expelling and inducing sweat, wind rash of can faling apart again.With the fever with chills controlled caused by affection of exogenous wind-cold, the disease such as lossless, normal and Ramulus Cinnamomi mutual reinforcement between is use, has the effect of relieving the exterior syndrome by diaphoresis.Thoroughly sending out smooth as controlled measles, when having cough symptom out of breath concurrently, can drink and adding Herba Ephedrae in letting eruptions out with drugs of pungent flavor and cool nature medicine, because of lung governing skin and hair, this product can lung qi dispersing, can disperse again, the effect of can receive rash, relievining asthma.Therefore clinical often with controlling the smooth caused throat itching and cough of exopathogen invasion and attack, lung qi, the diseases such as not well or urgent, uncomfortable in chest, the asthma of coughing of coughing up phlegm.
Ramulus Cinnamomi: be the dry twig of canella Cortex Cinnamomi Cinnamomum cassia Presl.Nature and flavor: acrid, sweet, warm.GUIXIN, lung, urinary bladder channel.Effect: diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins.Cure mainly exterior syndrome due to wind-cold; Arthralgia due to cold-dampnes; WEIJIA is lumpd; The thoracic obstruction; Cardiopalmus; Phlegm retention." Changsha medicine solution " carries: " enter liver man and promoting the circulation of blood divides, determine meridians and reach Rong Yu.Kind solution ailment said due to cold or exposure, adjusts wood gas most.The detrapping of sending up the lucid YANG, the punching of the turbid descending the moon is inverse, the anxious contraction of relaxing muscles and tendons feeling pulse; The heap soil or fertilizer over and around the roots resistance in profit joint, fall apart and suppress, pain relieving Chu, the meridian dredging, opens numbness puckery, very dries cold.Only renal mass, more pacifies palpitation with fear." modern medicine study confirm, Ramulus Cinnamomi can effectively blood vessel dilating, promote diaphoresis, contained cinnamic aldehyde, natrium cinnamicum have antipyretic, analgesia, calmness, anticonvulsant action, in addition Ramulus Cinnamomi antibacterial, antiviral effect in addition.Ramulus Cinnamomi is warm in nature, and the kind gas that activates yang, can change YIN-cold, temperature three-way meridian, for all pain cards of congealing cold with blood stasis.
The Radix Paeoniae Alba: be the dry root of dicotyledon ranunculaceae plant Radix Paeoniae Paeonia lactiflora Pall..Nature and flavor: cool, picric acid, is slightly cold.Effect: easing the affected liver of enriching blood, suppressing the hyperactive liver pain relieving, yin fluid astringing receives antiperspirant.Research shows: the paeoniflorin contained in the Radix Paeoniae Alba has antibacterial, antipyretic, antiinflammatory, increase coronary flow, improves the effect of myocardial nutritional flow, blood vessel dilating, antagonism acute myocardial ischemia, anticoagulant, calmness, analgesia, spasmolytic, antiulcer, adjustment blood glucose.Radix Paeoniae Alba decoct can suppress dysentery bacterium, streptococcus pneumoniae, escherichia coli, Bacillus typhi, Hemolytic streptococcus, bacillus pyocyaneus etc.This product energy nourishing the liver blood, holding back liver-yin, subduing the hyperfunction of the liver sun, dispersing liver-energy, can delay again that contraction is anxious, relieve the pain pain, is the good medicine of the various pain for the treatment of Liver Channel.
Exocarpium Citri Rubrum: be the dry outside rind of rutaceae Huazhou Fructus Citri tangerinae Citrus grandis Osbeck var. tomentosa Hort. or Fructus Citri tangerinae Citrus reticulata Blanco and variety thereof.Nature and flavor: pungent, bitter, temperature.Return lung, spleen channel.Effect: cold expelling, dampness, promoting the circulation of QI, expectorant.For cough due to wind and cold, itching of the throat abundant expectoration, food stagnation is got sick from drinking too much wine, and vomiting and nausea painful abdominal mass is vexed." medicineization justice ": Exocarpium Citri Rubrum, pungently can walk crosswise eliminating stagnation, and bitter decline of keeping straight on is promoting the circulation of QI key medicine.Lid is controlled expectorant and must be regulated the flow of vital energy, the spontaneous recovery of diarrhea due to disorder of QI expectorant, therefore with entering lung spleen, all expectorant main are sick, and merit occupies on all expectorant medicines.Assistant Caulis Bambusae In Taenia, to treat heat-hiccup, helps Pericarpium Citri Reticulatae Viride with intestinal stasis relieving gas, real in the flat stomach of same Rhizoma Atractylodis, Cortex Magnoliae Officinalis, and the heresy that conjunction Bulbus Allii Fistulosi, Herba Ephedrae exterior cold are wet, rapid digestion of food gas, alcoholic intoxication, anti-nausea, opens chest and diaphragm painful abdominal mass plug, can push away Chen Zhixin, and the power that all pungent loose hardship is fallen also.
Radix Platycodonis: be the root of dicotyledon campanulaceae Campanulaceae Radix Platycodonis Platycodon grandiflorum (Jacq.) A. DC..Nature and flavor are bitter, pungent, tepor.Enter lung meridian.Effect: lung qi dispersing, eliminate the phlegm, sore-throat relieving, evacuation of pus, sharp the five internal organs, fill blood, mend five kinds of over strain, foster the spirit of nobility.Radix Platycodonis is lung meridian edema caused by disorder of QI medicine, and pains are put down, and namely rises and falls, being good at a surname and opening lung qi, therefore exopathogen violates lung, cough with copious phlegm, and disease such as grade uncomfortable in chest of having a stuffy nose, no matter cold and heat all can adapted.
Herba Schizonepetae: be the dry aerial parts of labiate Herba Schizonepetae Schizonepeta tenuifolia Briq..Nature and flavor: pungent, bitter, micro-wet.Return lung, Liver Channel.Effect: dispel the wind; Induce sweat; Rash; Hemostasis.Main cold, fever; Headache; Eye itching; Cough; Laryngopharynx swelling and pain; Measles; Carbuncle; Skin ulcer scabies; Epistaxis; Spit blood; Have blood in stool; Metrorrhagia; Puerperal blood faints.This product Chhnang is loose thoroughly, can dispelling wind for relieving itching, and the loose measles toxin of a surname, can be used for measles without adequate eruption, rubella pruritus, in addition Herba Schizonepetae also can be used for skin infection from the beginning of, relatively wind heat this, compatibility Flos Loniceraes etc., Herba Schizonepetae and Radix Saposhnikoviae mutual reinforcement between are use, strengthen expelling pathogenic wind from the body surface effect.
Radix Saposhnikoviae: be the dry root of umbelliferae Saposhnikovia divaricata Saposhnikovia divaricata (Turcz.) Schischk..Nature and flavor: pungent, sweet, tepor.Return bladder, lung, spleen, Liver Channel.Effect: expelling pathogenic wind from the body surface, removing dampness to relieve pain, spasmolytic, antipruritic.For diseases caused by exogenous pathogenic factor exterior syndrome or rubella pruritus.This product slightly warm in nature and not dry, sweet slow and not high, there is the title of " the profit agent in wind medicine ", no matter wind and cold, wind heat exterior syndrome all can be applied.This product also can be used for tetanus, gnathospasma, opisthotonus.Radix Saposhnikoviae controls tetanus, has the effect of expellingging wind and relieving convulsion.
Flos Lonicerae: the flower that dry flower or band for caprifoliaceae plant Radix Ophiopogonis Lonicera japonica Thunb., Flos Lonicerae Lonicera hypoglauca Miq., Flos Lonicerae (hair calyx Radix Ophiopogonis) Lonicera confusa DC. or hair style Radix Ophiopogonis Lonicera dasystyla Rehd. are just opened.Nature and flavor: sweet, cold.Return lung, the heart, stomach warp.Effect: heat-clearing and toxic substances removing, wind-dispelling heat-dissipating.This product is sweet in flavor and cold in property, can heat-clearing and toxic substances removing, again kind loose carbuncle detumescence, for treating the key medicine of all YANG syndrome carbuncle furuncle.Clinically for carbuncle furunculosis: be often equal to use with Herba Violae, Flos Chrysanthemi Indici, can antipyretic and antidote functions be strengthened, can in order to carbuncle furunculosis, congestion and swelling pain.Flos Lonicerae sweet in the mouth is cold in nature, fragrant odour, both can relieving the exterior syndrome clearly thoroughly, can separate noxious heat in the blood system again, particularly control the key medicine of positive skin infection.
Radix Scutellariae: be the dry root of labiate Radix Scutellariae Scutellaria baicalensis Georgi.Nature and flavor: bitter, cold.Return lung, gallbladder, spleen, stomach, large intestine, small intestine meridian.Effect: heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive, blood pressure lowering.The clinical practice of Radix Scutellariae is antibacterial relatively good, and does not develop immunity to drugs.This product has the merit of clearing away heat and cooling blood hemostasis, intimately flourishing with controlling, the haematemesis etc. of the absurd row of forcing blood.
Herba Houttuyniae: be the drying water upper part of Saururaceae herbaceos perennial Herba Houttuyniae Houttuynia cordata Thunb..Property: be slightly cold, bitter in the mouth.Return lung meridian, bladder, large intestine channel.Effect: heat-clearing and toxic substances removing; Removing pus and relieving carbuncle; Inducing diuresis for treating stranguria syndrome.Raise a kind of yellow oil in Herba Houttuyniae, all have inhibitory action to various microorganism (especially yeast and mycete), have obvious inhibitory action to the streptococcus of hemolytic, staphylococcus aureus, hemophilus influenza, micrococcus catarrhalis, streptococcus pneumoniae.Also effect is had to escherichia coli, dysentery bacterium, Bacillus typhi.In vitro tests proves, Herba Houttuyniae decoct all has inhibitory action in various degree to multiple gram-positive bacteria and negative bacteria such as staphylococcus aureus, Staphylococcus albus, Hemolytic streptococcus, Diplococcus pneumoniae, micrococcus catarrhalis, diphtheria corynebacterium, Bacillus proteus, will he, Amur, Fu Shi and bacterium sonnei, bacillus enteritidis etc.
Radix Salviae Miltiorrhizae: be the dry root and rhizome of dicotyledon Labiatae Labiatae salvia Radix Salviae Miltiorrhizae Salvia/miltiorrhizaBge.Nature and flavor: bitter, are slightly cold.Gui Jing: enter the heart, Liver Channel.Effect: promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, clear away heart-fire relieving restlessness, nourishing blood to tranquillize the mind.For costa sternales hypochondriac pain, rheumatic arthralgia, lump in the abdomen lumps." Japan hanako materia medica ": sedate of reposing, tonneau GUAN-pulse.Control cold and hot labor, arthralgia, extremity are unsuccessful; Evacuation of pus pain relieving, granulation promoting is put on flesh; Broken stagnated blood, mends new hemopoietic; Peaceful tire, fall stillborn fetus; Under hemostasis metrorrhagia and leukorrhagia, adjust married woman's passages through which vital energy circulates irregular, blood evil thought is tired of; Malignant boil scabies, wart is gone to live in the household of one's in-laws on getting married toxic swelling, erysipelas; Headache, acute conjunctivitis, hot temperature is mad vexed.
Spina Gleditsiae: be the dry Spina jujubae of leguminous plant Fructus Gleditsia Gleditsia sinensis Lam..Nature and flavor: pungent, temperature.Return lung, Liver Channel.Effect: detumescence and apocenosis, promoting blood circulation by removing wind.Tcm clinical practice is used for swollen ulcer drug all good therapeutic effect, generally shows as the non-Cheng Zheke of pus and disappears, and formed pus person can make it speed and burst.Modern anticancer pharmacological research shows, Spina Gleditsiae has anticancer tumor-suppression activity.Modern pharmacology is studied its decoct flat board and to be burrowed method, has inhibitory action to staphylococcus aureus and micrococcus catarrhalis.It is up that Spina Gleditsiae can draw all medicines, the kind disease controlling the part of the body cavity above the diaphragm housing the heart and lungs.
Flos Carthami: be the tubular corolla of feverfew Flos Carthami Carthamus tinctorius L..Nature and flavor: temperature, pungent.GUIXIN, Liver Channel.Effect: promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.The pungent loose temperature of Flos Carthami is led to, and specially enters blood system, can blood circulation promoting and blood stasis dispelling, and stimulate the menstrual flow pulse-taking, and the mutual reinforcements between such as normal and Semen Persicae, Radix Angelicae Sinensis, Rhizoma Chuanxiong are for use.Flos Carthami has blood vessel dilating effect.Carthamus yellow can obviously extend blood plasma recalcification time, prothrombin time and clotting time." Amplification on Materia Medica addendum ": Flos Carthami, broken stagnant blood, nourishes blood.Multiplex then removing blood stasis is few with then nourishing blood.
Semen Persicae (parched): be the dry mature seed of rosaceous plant Fructus Persicae Prunus persica (L.) Batsch or Prunus davidiana Prunus davidiana (Carr.) Franch..Nature and flavor: bitter, sweet, flat.GUIXIN, liver, large intestine channel.Effect: blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, relieving cough and asthma.The power of Semen Persicae blood stasis dispelling is comparatively strong, also known as stasis-breaking drug, is used for the treatment of blood stasis, WEIJIA, often joins Flos Carthami, Radix Angelicae Sinensis.Semen Persicae is improved effect to blood flow retardance, blood obstacle, and each internal organs can be made respectively to organize functional recovery normal.
Pheretima: be the dry body of Ju Yin section animal Pheretima aspergillum Pheretima aspergillum (E. Perrier), popular Pheretimatschiliensis Pheretima vulgaris Chen, power simulation Pheretima guillelmi (Michaelsen) or comb blind Pheretimatschiliensis Pheretima pectinifera Michaelsen.Nature and flavor: salty, cold.Return liver, spleen, urinary bladder channel.Effect: heat clearing away is calmed the frightened, dredge the meridian passage, clearing heat and relieving dyspnea, relieving stranguria by diuresis.
Hirudo (processed): be the dry body of Hirudinidae animal whitmania Whitmania pigra Whitman, Hirudo Hirudo nipponica Whitman or Folium Salicis Babylonicae Hirudo Whit-mania acranulata Whitman.Nature and flavor: salty, bitter, flat, slightly poisonous.Return Liver Channel.There is removing blood stasis, removing blood stasis, the effect of stimulating the menstrual flow, Yong Yu mass in the abdomen mass in the abdomen, blood stasis amenorrhea, injury from falling down.The salty hardship of Hirudo enters blood system, is good at removing blood stasis by silt, and the high effect of power is grand, and modern age is clinical in controlling thrombocytosis, and decoction in short-term has certain curative effect, controls cerebral hemorrhage, intracranial hematoma, has good curative effect.
Radix Cyathulae: be the dry root of amaranthaceous plant Radix Cyathulae Cyathula officinalis Kuan.Nature and flavor: sweet, micro-hardship, flat.Return liver, kidney channel.Effect: eliminating blood stasis and inducing menstruation, easing joint movement, inducing diuresis for treating stranguria syndrome.For amenorrhea lump in the abdomen, retention of placenta, arthralgia, flaccidity of the lower limbs clonic spasm of the muscle, hematuria stranguria with blood, injury from falling down.
The Radix Astragali: be the dry root of leguminous plant Radix Astagali Astragalus membranaceus (Fisch.) Bge. var. mongholicus (Bge.) Hsiao or Radix Astragali Astragalus membranaceus (Fisch.) Bge..Nature and flavor: sweet, tepor.Return lung, spleen, liver, kidney channel.Effect: tonifying Qi and lifting yang, consolidating superficial resistance arresting sweating, inducing diuresis to remove edema, the evacuation of pus of holder skin ulcer, regulating fluid apssage.On the books in " book on Chinese herbal medicine converges and says ": " Radix Astragali, tonifying the lung spleen invigorating defend arresting sweating in fact, and the medicine of wind dispelling fortune poison also.Therefore the people of yang deficiency, spontaneous perspiration frequently comes, be exterior deficiency and interspaces of skin and muscles being loose also, he the Radix Astragali can be defended and arresting sweating in fact; The card of typhoid fever, row is delivered and evil no sweating, and be interior deficiency and also weary in healthy energy, the Radix Astragali can help Tianjin to help antiperspirant; The disease of harmful wind, inclined invasion of vessels and brothers are not with person, and the Radix Astragali can flourish muscles and bones; The card of carbuncle and ulcer, pus and blood internal ulceration, deficiency of YANG QI and do not hold back person, the Radix Astragali can granulation promoting meat, and the erosion of vulva can not rise and send out again, deficiency of YANG QI and unhealed, and the Radix Astragali can granulation promoting meat." this product all has inhibitory action to dysentery bacterium, anthrax bacillus, α-hemolytic streptococcus, beta hemolytic streptococcus, diphtheria corynebacterium, bacillus pseudodiphthericus, Diplococcus pneumoniae, staphylococcus aureus, Staphylococcus citreus, bacillus subtilis etc. in vitro.
Rhizoma Polygonati: be the dry rhizome of liliaceous plant P. kingianum Polygonatum kingianum Coll.et Hemsl., Rhizoma Polygonati Polygonatum sibiricum Red. or Polygonatum cyrtonema Hua Polygonatum cyrtonema Hua.Nature and flavor: sweet are flat.Return spleen, lung, kidney channel.Effect: boosting qi and nourishing yin, spleen invigorating, lung moistening, kidney tonifying.For weakness of the spleen and stomach, fatigue and asthenia, xerostomia lack of appetite, deficiency of the lung cough caused by dryness, asthenia of essence and blood, interior-heat is quenched one's thirst." book on Chinese herbal medicine is just read ": Rhizoma Polygonati, for growing greasy product, clothes of a specified duration make us not hungry, have wet person if insufficiency of the spleen, should not take it, and probably its greasy diaphragm also.These flavour of a drug are sweet as maltosemalt sugar, and the flat matter profit of property is the certified products of tonic spleen the moon.
Rhizoma Phragmitis: be the fresh or dry rhizome of grass phragmites communis Phragmites communis Trin..Nature and flavor: sweet, cold.Return lung meridian, stomach warp.Function: clearing away heat and promoting production of body fluid, relieving restlessness, preventing or arresting vomiting, diuresis.Cure mainly: for calentura excessive thirst, gastropyretic vomiting, cough due to lung-heat, lung abscess vomiting pus, the puckery pain of pyretic stranguria.Rhizoma Phragmitis one medicine, is mainly used in following two aspects clinically, can clearing away lung-heat and evacuation of pus of eliminating the phlegm, again can clearing away stomach-heat and the preventing or arresting vomiting that promotes the production of body fluid.Though its attribute is trembled with fear, slightly sweet flavor and power use lung heat clearing stomach, can only as auxiliary medicine.But, it has an advantage, and namely property is not grown greasy, promotes the production of body fluid and does not love heresy, and all epidemic febrile disease deep loves are defended, gas, or if any the syndrome that impairment of body fluid is thirsty after calentura, all can apply.
Radix Angelicae Sinensis: be the dry root of umbelliferae angelica Angelica sinensis (Oliv.) Diels.Nature and flavor: sweet, pungent, bitter, temperature.Return liver, the heart, spleen channel.Effect: enrich blood; Invigorate blood circulation; Menstruction regulating and pain relieving; Moisturize laxation.Radix Angelicae Sinensis has inhibitory action to central nervous system, and volatile oil has the effects such as calmness, hypnosis, analgesia, anesthesia.For blood deficiency and yellow complexion, dizzy cardiopalmus, asthenia cold abdominalgia, rheumatic arthralgia, injury from falling down, ulcer sores.Carry according to " book on Chinese herbal medicine is just ": " its sweet in the mouth and weigh, therefore specially can enrich blood, its gas is light and pungent, therefore again can promoting the circulation of blood, can support nutrition blood, QI invigorating spermatogenesis, settling five organs, strong body, beneficial mind, all tangible deficient diseases, nothing unsuitable." modern medicine study confirmation, Radix Angelicae Sinensis has antibacterial, antiinflammation, and Radix Angelicae Sinensis hot water extract has obvious inhibitory action to during chronic articular rheumatism acute attack.
Radix Glycyrrhizae Preparata: be the dry root and rhizome of glycyrrhizic legume Glycyrrhiza uralensis Fisch., Glycyrrhiza inflata Bat. Glycyrrhiza Inflata Bat. or Glycyrrhiza glabra L. Glycyrrhiza Glabra L..Radix Glycyrrhizae Preparata is that processed goods smoked by the honey of Radix Glycyrrhizae.Nature and flavor: sweet are flat.GUIXIN, lung, spleen, stomach warp.Effect: spleen reinforcing stomach function regulating, Yiqi and vein recovery." Japan hanako materia medica ": peace soul determines soul.Mend five kinds of strain and seven kinds of impairment, all be deficient, palpitation with fear, unhappy, forgetful.Logical nine orifices, sharp hundred arteries and veins, beneficial intensive culture gas, strengthening bone and muscle, separates cold and hot.
Side's solution of the present invention is: Radix Bupleuri dispersing the stagnated live-QI to relieve the stagnation of QI, ascending up spleen-Qi and Yang in side, the heat clearing away of chrysanthemum powder forimproving wind, Radix Ophiopogonis nourishing lung-YIN, clear away heart-fire relieving restlessness, Radix Scrophulariae clearing away heat and cooling blood, eliminating fire and detoxication, Radix Rehmanniae clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting, Herba Ephedrae diaphoresis cold expelling, depressed lung-energy dispersing, above Six-element is monarch drug altogether, mainly play the effect of YIN nourishing and the production of body fluid promoting, diaphoresis cold expelling, fundamentally carry out nourishing lungs from patient body, repair impaired lungs, also there is effect of clearing away heat and cooling blood, dispersing the stagnated live-QI to relieve the stagnation of QI simultaneously, the hypopnea of patient therefore caused by disease can be treated, the symptoms such as heart failure.Ramulus Cinnamomi is supporing yang activating QI, the flat gas that spins, enrich blood easing the affected liver, yin fluid astringing of the Radix Paeoniae Alba receives antiperspirant, the expectorant of Exocarpium Citri Rubrum promoting the circulation of QI, Radix Platycodonis lung qi dispersing eliminates the phlegm, sore-throat relieving evacuation of pus, Herba Schizonepetae, Radix Saposhnikoviae expelling pathogenic wind from the body surface, Flos Lonicerae heat-clearing and toxic substances removing, Radix Scutellariae heat clearing and damp drying, eliminating fire and detoxication, above eight tastes are ministerial drug altogether, and majority has the effect of anti-inflammation, heat-clearing and toxic substances removing, can resist exopathogen invasion, improve patient's resistance, increase monarch drug drug effect simultaneously, increase pulmonary's tension force, reduce the appearance of dyspnea symptom.Herba Houttuyniae heat-clearing and toxic substances removing, Radix Salviae Miltiorrhizae clears away heart-fire relieving restlessness, nourishing blood to tranquillize the mind, Spina Gleditsiae detumescence and apocenosis, Flos Carthami, Semen Persicae (parched) blood circulation promoting and blood stasis dispelling, Pheretima, Hirudo (processed) heat clearing away is calmed the frightened, dredge the meridian passage, Radix Cyathulae eliminating blood stasis and inducing menstruation, Radix Astragali tonifying Qi and lifting yang, inducing diuresis to remove edema, Rhizoma Polygonati boosting qi and nourishing yin, Rhizoma Phragmitis clearing away heat and promoting production of body fluid, Chinese angelica blood supplementing is invigorated blood circulation, a few taste is adjuvant drug altogether above, also there is the effect of tonifying Qi and lifting yang while tonifying the lung, this sick the kidney usually involved in chronic disease, suffer from a deficiency of the kidney and can not have lower-jiao Qi dysfunction under one's command, causing its gasification expands between punching is appointed, qi of chong channel ascending adversely, gastric qi and irritability upper punch all thereupon, the gas of suction is caused not received by the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels is amiable and compliant, and turn by part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels impulse, tonifying Qi and lifting yang thus pulmonary's improving inspiration by invigorating kidney-QI can be contributed to, thus reach the object of disease therapy.Radix Glycyrrhizae Preparata spleen reinforcing stomach function regulating, coordinating the actions of various ingredients in a prescription, priming return through, for making medicine.The all medicines of this side share, and the monarch and his subjects pull together, and assistant makes auxiliary altogether, has effect of nourishing lung-YIN, clearing away heat and cooling blood, depressed lung-energy dispersing, sore-throat relieving evacuation of pus, effectively can treat chronic obstructive pulmonary disease.
Medicine material consumption of the present invention is groped to sum up to draw through inventor in a large number, each raw material dosage is for all to have good curative effect in following weight parts scope: Radix Bupleuri 10-20 part, Flos Chrysanthemi 7-17 part, Radix Ophiopogonis 10-20 part, Radix Scrophulariae 10-20 part, Radix Rehmanniae 13-23 part, Herba Ephedrae 4-14 part, Ramulus Cinnamomi 10-20 part, Radix Paeoniae Alba 10-20 part, Exocarpium Citri Rubrum 7-17 part, Radix Platycodonis 15-25 part, Herba Schizonepetae 7-17 part, Radix Saposhnikoviae 5-15 part, Flos Lonicerae 13-23 part, Radix Scutellariae 10-20 part, Herba Houttuyniae 15-25 part, Radix Salviae Miltiorrhizae 19-29 part, Spina Gleditsiae 19-29 part, Flos Carthami 5-15 part, Semen Persicae (parched) 7-17 part, Pheretima 7-17 part, Hirudo (processed) 4-14 part, Radix Cyathulae 13-23 part, Radix Astragali 25-35 part, Rhizoma Polygonati 15-25 part, Rhizoma Phragmitis 25-35 part, Radix Angelicae Sinensis 13-23 part, Radix Glycyrrhizae Preparata 4-14 part.
Wherein be preferably: Radix Bupleuri 15 parts, Flos Chrysanthemi 12 parts, Radix Ophiopogonis 15 parts, Radix Scrophulariae 15 parts, Radix Rehmanniae 18 parts, 9 parts, Herba Ephedrae, Ramulus Cinnamomi 15 parts, the Radix Paeoniae Alba 15 parts, Exocarpium Citri Rubrum 12 parts, Radix Platycodonis 20 parts, Herba Schizonepetae 12 parts, Radix Saposhnikoviae 10 parts, Flos Lonicerae 18 parts, Radix Scutellariae 15 parts, Herba Houttuyniae 20 parts, Radix Salviae Miltiorrhizae 24 parts, Spina Gleditsiae 24 parts, 10 parts, Flos Carthami, Semen Persicae (parched) 12 parts, Pheretima 12 parts, Hirudo (processed) 9 parts, Radix Cyathulae 18 parts, the Radix Astragali 30 parts, Rhizoma Polygonati 20 parts, Rhizoma Phragmitis 30 parts, Radix Angelicae Sinensis 18 parts, Radix Glycyrrhizae Preparata 9 parts.
A kind of preparation method for the treatment of the Chinese medicine preparation of chronic obstructive pulmonary disease is as follows:
Step one: by weight proportion of the present invention, by Radix Ophiopogonis, Radix Scrophulariae, Radix Rehmanniae, the Radix Paeoniae Alba, Radix Saposhnikoviae, Radix Scutellariae, Radix Salviae Miltiorrhizae, Radix Cyathulae, the Radix Astragali, Rhizoma Phragmitis is put into marmite and is added cold water, exceed powder 3 ~ 4 centimetres, after being fried boiling with high heat, again with 20 ~ 30 minutes at a simmer, filter, obtain filtrate, the water of 3 ~ 4 centimetres is added in residue medicinal residues, then Radix Bupleuri is added, Herba Ephedrae, Ramulus Cinnamomi, Fructus Citri tangerinae is red, Radix Platycodonis, Herba Schizonepetae, Herba Houttuyniae, Spina Gleditsiae, Rhizoma Polygonati, Radix Angelicae Sinensis decocts 20 ~ 30 minutes, finally add Flos Chrysanthemi, Flos Lonicerae, Flos Carthami, Pheretima, Radix Glycyrrhizae Preparata continues decoction 10 minutes, filter, obtain filtrate, merge twice filtrate, and when filtrate being concentrated into 80 DEG C-85 DEG C, add 75% ethanol, place precipitation, filter, abandon precipitation, filtrate recycling ethanol, the thick paste of relative density 1.13 ~ 1.20 under 60 DEG C of environment,
Step 2: by weight proportion of the present invention, grinds into powder be crushed to 200 mesh sieves by Semen Persicae (parched), Hirudo (processed), for subsequent use;
Step 3: in step 2, gained fine powder adds in step one gained thick paste and is uniformly mixed, dry, be ground into fine powder, add appropriate Icing Sugar as diluent, ethanol as wetting agent and microcrystalline Cellulose as disintegrating agent, adopt dry granulation, make 10g/ bag, every bag of granule containing crude drug 5g.
Medicine of the present invention has the effects such as nourishing lung-YIN, clearing away heat and cooling blood, depressed lung-energy dispersing, sore-throat relieving evacuation of pus, and it is evident in efficacy, cheap, easy to use, have no side effect, no dependence, the mode that this Chinese medicine preparation adopts is treated and can be reduced the damage of Western medicine to patient's hepatic and renal function, accelerates the improvement of the state of an illness.According to clinical 200 routine patient view statistics, use medicine of the present invention the total effective rate course for the treatment of 90%, two the total effective rate course for the treatment of 98%.
Detailed description of the invention
Embodiment one, Radix Bupleuri 10 parts, Flos Chrysanthemi 7 parts, Radix Ophiopogonis 10 parts, Radix Scrophulariae 10 parts, Radix Rehmanniae 13 parts, 4 parts, Herba Ephedrae, Ramulus Cinnamomi 10 parts, the Radix Paeoniae Alba 10 parts, Exocarpium Citri Rubrum 7 parts, Radix Platycodonis 15 parts, Herba Schizonepetae 7 parts, Radix Saposhnikoviae 5 parts, Flos Lonicerae 13 parts, Radix Scutellariae 10 parts, Herba Houttuyniae 15 parts, Radix Salviae Miltiorrhizae 19 parts, Spina Gleditsiae 19 parts, 5 parts, Flos Carthami, Semen Persicae (parched) 7 parts, Pheretima 7 parts, Hirudo (processed) 4 parts, Radix Cyathulae 13 parts, the Radix Astragali 25 parts, Rhizoma Polygonati 15 parts, Rhizoma Phragmitis 25 parts, Radix Angelicae Sinensis 13 parts, Radix Glycyrrhizae Preparata 4 parts.
Embodiment two, Radix Bupleuri 15 parts, Flos Chrysanthemi 12 parts, Radix Ophiopogonis 15 parts, Radix Scrophulariae 15 parts, Radix Rehmanniae 18 parts, 9 parts, Herba Ephedrae, Ramulus Cinnamomi 15 parts, the Radix Paeoniae Alba 15 parts, Exocarpium Citri Rubrum 12 parts, Radix Platycodonis 20 parts, Herba Schizonepetae 12 parts, Radix Saposhnikoviae 10 parts, Flos Lonicerae 18 parts, Radix Scutellariae 15 parts, Herba Houttuyniae 20 parts, Radix Salviae Miltiorrhizae 24 parts, Spina Gleditsiae 24 parts, 10 parts, Flos Carthami, Semen Persicae (parched) 12 parts, Pheretima 12 parts, Hirudo (processed) 9 parts, Radix Cyathulae 18 parts, the Radix Astragali 30 parts, Rhizoma Polygonati 20 parts, Rhizoma Phragmitis 30 parts, Radix Angelicae Sinensis 18 parts, Radix Glycyrrhizae Preparata 9 parts.
Embodiment three, Radix Bupleuri 20 parts, Flos Chrysanthemi 17 parts, Radix Ophiopogonis 20 parts, Radix Scrophulariae 20 parts, Radix Rehmanniae 23 parts, 14 parts, Herba Ephedrae, Ramulus Cinnamomi 20 parts, the Radix Paeoniae Alba 20 parts, Exocarpium Citri Rubrum 17 parts, Radix Platycodonis 25 parts, Herba Schizonepetae 17 parts, Radix Saposhnikoviae 15 parts, Flos Lonicerae 23 parts, Radix Scutellariae 20 parts, Herba Houttuyniae 25 parts, Radix Salviae Miltiorrhizae 29 parts, Spina Gleditsiae 29 parts, 15 parts, Flos Carthami, Semen Persicae (parched) 17 parts, Pheretima 17 parts, Hirudo (processed) 14 parts, Radix Cyathulae 23 parts, the Radix Astragali 35 parts, Rhizoma Polygonati 25 parts, Rhizoma Phragmitis 35 parts, Radix Angelicae Sinensis 23 parts, Radix Glycyrrhizae Preparata 14 parts.
Here is the clinical statistics data that patient uses medicine of the present invention:
One, physical data
Accept out-patient 400 example for medical treatment.Patient is divided into observation group and matched group at random, wherein male 220 example, women 180 example, M-F 1.2:1,46 years old mean age, every basic documents such as two groups of patient ages, sex, courses of disease are substantially identical, no significant difference (P > 0.05).
Two, Therapeutic Method
1, observation group is according to Medications Example two of the present invention, and granule prepared by preferred preparation method, and boiled water is taken after mixing it with water, every day 3 times, each one bag.It within 15th, is a course for the treatment of.
2, matched group conveniently western medicine method, carries out symptomatic treatment to it, within 15 days, is an observation period.
Three, efficacy assessment standard
1, cure: dyspnea, expectoration, cough, heavy breathing toot the transference cure such as sound, cyanosis, blood gas index recovers normal, and body constitution recovers normal, and every inspection is all normal.
2, take a turn for the better: dyspnea, expectoration, cough, heavy breathing toot the symptom such as sound, cyanosis alleviate, blood gas index takes a turn for the better, and body constitution takes a turn for the better gradually, and indices recovers all to some extent.
3, do not heal: various clinical symptoms is without any improvement, even increases the weight of.
Four, observation group's result statistics
Matched group result is added up
Wherein: total effective rate=cure rate+improvement rate
Take the Comparison of therapeutic situation of two groups of patients, two courses for the treatment of
Can find that observation group is apparently higher than matched group by the treatment total effective rate contrasting two groups of patients, illustrate thus, Chinese medicine of the present invention has good clinical effectiveness in treatment chronic obstructive pulmonary disease, effectively can improve the cure rate for the treatment of, be worth promoting in clinical practice.
Model case and curative effect:
Case one, Guo, man, 53 years old, patient coughs, expectoration is had a surplus March, with the phenomenon of heating time serious, breast is had vexed after activity, the phenomenon of panting, patient goes to hospital to check, be diagnosed as chronic obstructive pulmonary disease, patient's oral western medicine about two weeks, transference cure, but how long do not have, patient coughs, expectoration, the phenomenon of breathing hard recurs again, patient determines the Therapeutic Method adopting Chinese medicine, use case two method of the present invention, after taking a course for the treatment of, patient coughs and obviously alleviates, asthma phenomenon is also eased, because patient's body constitution is poor, for consolidating drug effect, continue two courses for the treatment of of drug administration, cough, other symptoms such as expectoration disappear completely, body constitution also increases, breast is vexed, phenomenon of breathing hard disappears, remove examination in hospital, indices all shows normally, have no recurrence, recovery from illness.
Case two, in certain, man, 61 years old half, patient is because of cough, admission examination of breathing hard, and be finally diagnosed as chronic obstructive pulmonary disease, patient adopts case two method of the present invention, after taking a course for the treatment of, cough alleviates, and amount of expectoration reduces, after continue to take a course for the treatment of, patient's cough, phenomenon of breathing hard disappear completely, and body constitution also strengthens to some extent, and patient goes to hospital to check, every inspection is normal, recovery from illness.
Case three, Zhang, female, 50 years old, patient because of cough expectorant companion tachypnea have a surplus January, since patient idiopathy, the mental status is not good, body constitution also declines gradually, patient itself has chronic bronchitis history, conditions of patients increases the weight of, occur breathing hard, the phenomenon of cardiopalmus, remove examination in hospital, finally be diagnosed as chronic obstructive pulmonary disease, patient adopts case two method of the present invention, after taking a course for the treatment of, cough, phenomenon of breathing hard is clearly better, the mental status is also taken a turn for the better, continue to take a course for the treatment of, patient coughs, breathe hard, cardiopalmus phenomenon disappears completely, other clinical symptoms are also taken a turn for the better, body constitution also strengthens to some extent, hospital is gone to check, indices all shows normally, recovery from illness.

Claims (4)

1. treat the Chinese medicine preparation of chronic obstructive pulmonary disease for one kind, it is characterized in that, this Chinese medicine preparation is made up of the medicine of following weight portion: Radix Bupleuri 10-20 part, Flos Chrysanthemi 7-17 part, Radix Ophiopogonis 10-20 part, Radix Scrophulariae 10-20 part, Radix Rehmanniae 13-23 part, Herba Ephedrae 4-14 part, Ramulus Cinnamomi 10-20 part, Radix Paeoniae Alba 10-20 part, Exocarpium Citri Rubrum 7-17 part, Radix Platycodonis 15-25 part, Herba Schizonepetae 7-17 part, Radix Saposhnikoviae 5-15 part, Flos Lonicerae 13-23 part, Radix Scutellariae 10-20 part, Herba Houttuyniae 15-25 part, Radix Salviae Miltiorrhizae 19-29 part, Spina Gleditsiae 19-29 part, Flos Carthami 5-15 part, Semen Persicae (parched) 7-17 part, Pheretima 7-17 part, Hirudo (processed) 4-14 part, Radix Cyathulae 13-23 part, Radix Astragali 25-35 part, Rhizoma Polygonati 15-25 part, Rhizoma Phragmitis 25-35 part, Radix Angelicae Sinensis 13-23 part, Radix Glycyrrhizae Preparata 4-14 part.
2. the Chinese medicine preparation of the treatment chronic obstructive pulmonary disease according to claims 1, it is characterized in that, be made up of the medicine of following weight portion: Radix Bupleuri 15 parts, Flos Chrysanthemi 12 parts, Radix Ophiopogonis 15 parts, Radix Scrophulariae 15 parts, Radix Rehmanniae 18 parts, 9 parts, Herba Ephedrae, Ramulus Cinnamomi 15 parts, the Radix Paeoniae Alba 15 parts, Exocarpium Citri Rubrum 12 parts, Radix Platycodonis 20 parts, Herba Schizonepetae 12 parts, Radix Saposhnikoviae 10 parts, Flos Lonicerae 18 parts, Radix Scutellariae 15 parts, Herba Houttuyniae 20 parts, Radix Salviae Miltiorrhizae 24 parts, Spina Gleditsiae 24 parts, 10 parts, Flos Carthami, Semen Persicae (parched) 12 parts, Pheretima 12 parts, Hirudo (processed) 9 parts, Radix Cyathulae 18 parts, the Radix Astragali 30 parts, Rhizoma Polygonati 20 parts, Rhizoma Phragmitis 30 parts, Radix Angelicae Sinensis 18 parts, Radix Glycyrrhizae Preparata 9 parts.
3. the Chinese medicine preparation for the treatment of chronic obstructive pulmonary disease according to claim 1 and 2, is characterized in that: described Chinese medicine preparation is granule.
4. treat the preparation method of the Chinese medicine preparation of chronic obstructive pulmonary disease for one kind, it is characterized in that, preparation method is as follows: step one: by weight proportion of the present invention, by Radix Ophiopogonis, Radix Scrophulariae, Radix Rehmanniae, the Radix Paeoniae Alba, Radix Saposhnikoviae, Radix Scutellariae, Radix Salviae Miltiorrhizae, Radix Cyathulae, the Radix Astragali, Rhizoma Phragmitis is put into marmite and is added cold water, exceed powder 3 ~ 4 centimetres, after being fried boiling with high heat, again with 20 ~ 30 minutes at a simmer, filter, obtain filtrate, the water of 3 ~ 4 centimetres is added in residue medicinal residues, then Radix Bupleuri is added, Herba Ephedrae, Ramulus Cinnamomi, Fructus Citri tangerinae is red, Radix Platycodonis, Herba Schizonepetae, Herba Houttuyniae, Spina Gleditsiae, Rhizoma Polygonati, Radix Angelicae Sinensis decocts 20 ~ 30 minutes, finally add Flos Chrysanthemi, Flos Lonicerae, Flos Carthami, Pheretima, Radix Glycyrrhizae Preparata continues decoction 10 minutes, filter, obtain filtrate, merge twice filtrate, and when filtrate being concentrated into 80 DEG C-85 DEG C, add 75% ethanol, place precipitation, filter, abandon precipitation, filtrate recycling ethanol, the thick paste of relative density 1.13 ~ 1.20 under 60 DEG C of environment, step 2: by weight proportion of the present invention, grinds into powder be crushed to 200 mesh sieves by Semen Persicae (parched), Hirudo (processed), for subsequent use, step 3: in step 2, gained fine powder adds in step one gained thick paste and is uniformly mixed, dry, be ground into fine powder, add appropriate Icing Sugar as diluent, ethanol as wetting agent and microcrystalline Cellulose as disintegrating agent, adopt dry granulation, make 10g/ bag, every bag of granule containing crude drug 5g.
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Application publication date: 20150805