CN106074981A - A kind of Chinese medicine composition treating superficial gastritis and preparation method thereof - Google Patents
A kind of Chinese medicine composition treating superficial gastritis and preparation method thereof Download PDFInfo
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- CN106074981A CN106074981A CN201610652446.1A CN201610652446A CN106074981A CN 106074981 A CN106074981 A CN 106074981A CN 201610652446 A CN201610652446 A CN 201610652446A CN 106074981 A CN106074981 A CN 106074981A
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/67—Piperaceae (Pepper family), e.g. Jamaican pepper or kava
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
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Abstract
The invention discloses a kind of Chinese medicine composition treating superficial gastritis, include following raw material by weight: the Radix Aucklandiae 35, Herba Belladonnae 35, Rhizoma Dioscoreae Hypoglaucae 6 18, Fructus Piperis Longi 13, Fructus Crataegi 68, Endothelium Corneum Gigeriae Galli 8 12, Herba Epimedii 13, Gypsum Fibrosum 13.
Description
Technical field
The present invention relates to application and the preparation field of pharmaceuticals, relate to a kind of Chinese medicine composition treating superficial gastritis.
Background technology
Stomachache, also known as gastric abscess, refers to pain at the nearly pit of the stomach in upper abdomen gastral cavilty portion, and the traditional Chinese medical science thinks that stomachache is that taste are impaired, QI and blood
The pain in uncomfortable caused gastral cavilty portion, how with diseases caused by exogenous pathogenic factor cold-evil, injury due to diet, feelings will is smooth and the cause of disease such as emptiness of spleen and stomach and draw
Sending out, add that modern's eating raw food is cold and cool, pressure is excessive, and the people of stomach discomfort gets more and more；The acute gastritis of doctor trained in Western medicine, chronic stomach
The above abdominal pains such as inflammation, gastric ulcer, duodenal ulcer, functional digestive obstacle are cardinal symptom, belong to the shallow table of Chinese medicine
Property gastritis scope.The method for the treatment of superficial gastritis has Chinese traditional treatment and western medical treatment at present, and western medical treatment is typically with A Moxi
Woods+omeprazole+metronidazole, i.e. triple therapy, antacid infection is main, substantially can only alleviate or release symptom, and long
Phase takes antibiotic, and injure one's stomach gas, causes patient's anorexia, malnutrition, and health is weaker.The traditional Chinese medical science with cold and heat and asthenia and sthenia,
Coldheat complex, relatively common, but ignore taste prolonged deficiency, long-pending silt is not smooth, and only balance taste negative and positive are not enough.Therefore cause treating
Imitating the best, Most patients feedback is only stomachache transference cure, but dietary amount does not increases, and digests and assimilates and do not improved.
Summary of the invention
It is an object of the invention to provide one and treat stomachache, and appetite and the Chinese medicine composition digested and assimilated can be improved.
The present invention is achieved through the following technical solutions:
A kind of Chinese medicine composition treating superficial gastritis, including the raw material of following weight portion: Radix Aucklandiae 3-5, Herba Belladonnae 3-
5, Rhizoma Dioscoreae Hypoglaucae 6-18, Fructus Piperis Longi 1-3, Fructus Crataegi 6-8, Endothelium Corneum Gigeriae Galli 8-12, Herba Epimedii 1-3, Gypsum Fibrosum 1-3.
Preferably, including the raw material of following weight portion: the Radix Aucklandiae 4, Herba Belladonnae 4, Rhizoma Dioscoreae Hypoglaucae 7, Fructus Piperis Longi 2, Fructus Crataegi 7, Endothelium Corneum Gigeriae Galli
10, Herba Epimedii 2, Gypsum Fibrosum 2.
The present invention also provides for the preparation method of a kind of Chinese medicine composition treating superficial gastritis: comprise following process step
Rapid: take the Radix Aucklandiae of each weight portion, Herba Belladonnae, Rhizoma Dioscoreae Hypoglaucae, Fructus Piperis Longi, Fructus Crataegi, Endothelium Corneum Gigeriae Galli, Herba Epimedii, Gypsum Fibrosum by proportion relation；Add
70% ethanol soaks 15 minutes at 60～65 DEG C, reflux, extract, 2-3 time, each 1 hour, and 100 mesh filters filter, and obtain extracting solution；
United extraction liquid, recovered under reduced pressure in input concentrating under reduced pressure tank, ethanol, to without alcohol taste, obtains concentrated solution；By concentrated solution at 70-100 DEG C
Being spray-dried or dry, be ground into the fine powder of 70-100 mesh, after granulation, Conventional compression or encapsulated, to obtain final product.
Prescription of the present invention is exquisite, each component synergism, warming spleen and stomach for dispelling cold, analgesia of releiving, and warming the stomach spleen invigorating, desilting helps digestion, right
Especially suitable in cold syndrome of the stomach person with Spleen Deficiency.
Detailed description of the invention
Embodiment 1
(1) take the Radix Aucklandiae 3 parts, Herba Belladonnae 3 parts, Rhizoma Dioscoreae Hypoglaucae 6 parts, Fructus Piperis Longi 1 part, Fructus Crataegi 6 parts, Endothelium Corneum Gigeriae Galli 8 parts, Herba Epimedii 1 part,
1 part of Gypsum Fibrosum is standby；
(2) adding 70% ethanol to soak 15 minutes at 60 DEG C, reflux, extract, 2 times, each 1 hour, 100 mesh filters filter,
Extracting solution；United extraction liquid, recovered under reduced pressure in input concentrating under reduced pressure tank, ethanol, to without alcohol taste, obtains concentrated solution；By concentrated solution 70
DEG C be spray-dried or dry, be ground into the fine powder of 70 mesh, encapsulated after granulation, specification 0.45g/ grain. each 3 times of morning, noon and afternoon, ante cibum
Take, each 3-5 grain.
Embodiment 2
(1) Radix Aucklandiae 5 parts, Herba Belladonnae 5 parts, Rhizoma Dioscoreae Hypoglaucae 8 parts, Fructus Piperis Longi 3 parts, Fructus Crataegi 8 parts, Endothelium Corneum Gigeriae Galli 12 parts, Herba Epimedii 3 are taken
Part, 3 parts of Gypsum Fibrosum standby；
(2) adding 70% ethanol to soak 15 minutes at 65 DEG C, reflux, extract, 3 times, each 1 hour, 100 mesh filters filter,
Extracting solution；United extraction liquid, recovered under reduced pressure in input concentrating under reduced pressure tank, ethanol, to without alcohol taste, obtains concentrated solution；Concentrated solution is existed
100 DEG C are spray-dried or dry, are ground into the fine powder of 100 mesh, encapsulated after granulation, specification 0.45g/ grain.
Embodiment 3
(1) Radix Aucklandiae 4 parts, Herba Belladonnae 4 parts, Rhizoma Dioscoreae Hypoglaucae 7 parts, Fructus Piperis Longi 2 parts, Fructus Crataegi 7 parts, Endothelium Corneum Gigeriae Galli 10 parts, Herba Epimedii 2 are taken
Part, 2 parts of Gypsum Fibrosum standby；
(2) adding 70% ethanol to soak 15 minutes at 62 DEG C, reflux, extract, 2 times, each 1 hour, 100 mesh filters filter,
Extracting solution；United extraction liquid, recovered under reduced pressure in input concentrating under reduced pressure tank, ethanol, to without alcohol taste, obtains concentrated solution；By concentrated solution 80
DEG C be spray-dried or dry, be ground into the fine powder of 90 mesh, encapsulated after granulation, specification 0.45g/ grain.
Clinical efficacy data
1, the effect observation that has a stomach-ache is treated
1.1 objects: superficial gastritis observes 500 people, with gastralgia, hyperchlorhydria and the chronic dietary stagnation of QI, defecate first
Half congealed, belch after hard.
1.2 medicine compositions: the Radix Aucklandiae 400 grams, Herba Belladonnae 400 grams, Rhizoma Dioscoreae Hypoglaucae 900 grams, Fructus Piperis Longi 200 grams, Fructus Crataegi 700
Gram, Endothelium Corneum Gigeriae Galli 1000 grams, Herba Epimedii 200 grams, 200 grams of Gypsum Fibrosum.
Said medicine adds 70% ethanol soak 15 minutes at 62 DEG C, reflux, extract, 2 times, each 1 hour, 100 mesh filters
Filter, obtain extracting solution；United extraction liquid, recovered under reduced pressure in input concentrating under reduced pressure tank, ethanol, to without alcohol taste, obtains concentrated solution；By dense
Contracting liquid is spray-dried at 80 DEG C or dries, and is ground into the fine powder of 90 mesh, and encapsulated after granulation, specification 0.45g/ grain, the morning, noon and afternoon are each
Once, bfore meals, each 3-5 grain.
1.3 curative effect judging standards:
Cure: gastralgia and other transference cures, x line, canel barium meal contrast examination or gastroscopy are normal.
Taking a turn for the better: stomachache is alleviated, outbreak reduces, other symptoms alleviate.
Not healing: x line, canel barium meal contrast examination or gastroscopy are the same with premorbid, symptom is without improving
And improvement.
Treatment stomachache 500 example effects
After using 30 days, 500 examples effective 358 examples of stomachache, take a turn for the better 99 examples, invalid 43 examples, obvious effective rate 72%, improvement rate
20%, total effective rate 92%.In use, all user all reflect that appetite improves, appetite increase, and stool form and
Color makes moderate progress.
Claims (3)
1. the Chinese medicine composition treating superficial gastritis, it is characterised in that include the raw material of following weight portion: Radix Aucklandiae 3-5,
Herba Belladonnae 3-5, Rhizoma Dioscoreae Hypoglaucae 6-8, Fructus Piperis Longi 1-3, Fructus Crataegi 6-8, Endothelium Corneum Gigeriae Galli 8-12, Herba Epimedii 1-3, Gypsum Fibrosum 1-3.
A kind of Chinese medicine composition treating superficial gastritis the most according to claim 1, it is characterised in that include following heavy
The raw material of amount part: the Radix Aucklandiae 4, Herba Belladonnae 4, Rhizoma Dioscoreae Hypoglaucae 7, Fructus Piperis Longi 2, Fructus Crataegi 7, Endothelium Corneum Gigeriae Galli 10, Herba Epimedii 2, Gypsum Fibrosum 2.
The preparation method of a kind of Chinese medicine composition treating superficial gastritis the most according to claim 1 and 2: its feature exists
In comprising following process steps: take the Radix Aucklandiae of each weight portion by proportion relation, Herba Belladonnae, Rhizoma Dioscoreae Hypoglaucae, Fructus Piperis Longi, Fructus Crataegi, Endothelium Corneum Gigeriae Galli,
Herba Epimedii, Gypsum Fibrosum；Add 70% ethanol to soak 15 minutes at 60～65 DEG C, reflux, extract, 2-3 time, each 1 hour, 100 mesh filters
Filter, obtain extracting solution；United extraction liquid, recovered under reduced pressure in input concentrating under reduced pressure tank, ethanol, to without alcohol taste, obtains concentrated solution；By dense
Contracting liquid is spray-dried at 70-100 DEG C or dries, and is ground into the fine powder of 70-100 mesh, Conventional compression or encapsulated after granulation, i.e.
?.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106389990A (en) * | 2016-10-26 | 2017-02-15 | 黔西南州神力中草药应用开发研究所 | Medicine for treating chronic superficial gastritis and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1768844A (en) * | 2005-10-19 | 2006-05-10 | 邱会恒 | Gastropathy dedicated Chinese medicine |
| CN104667052A (en) * | 2013-11-27 | 2015-06-03 | 邵艳艳 | Traditional Chinese medicinal formula for treating superficial gastritis |
| CN105343434A (en) * | 2015-12-11 | 2016-02-24 | 李建敏 | Traditional Chinese medicine composition for curing stomachache and preparation method thereof |
-
2016
- 2016-08-10 CN CN201610652446.1A patent/CN106074981A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1768844A (en) * | 2005-10-19 | 2006-05-10 | 邱会恒 | Gastropathy dedicated Chinese medicine |
| CN104667052A (en) * | 2013-11-27 | 2015-06-03 | 邵艳艳 | Traditional Chinese medicinal formula for treating superficial gastritis |
| CN105343434A (en) * | 2015-12-11 | 2016-02-24 | 李建敏 | Traditional Chinese medicine composition for curing stomachache and preparation method thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106389990A (en) * | 2016-10-26 | 2017-02-15 | 黔西南州神力中草药应用开发研究所 | Medicine for treating chronic superficial gastritis and preparation method thereof |
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